Hediye Erdjument‐bromage
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(Suggest an Edit or Addition)Hediye Erdjument‐bromage's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing (2002) (3621)
- SNAP receptors implicated in vesicle targeting and fusion (1993) (3178)
- mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery (2002) (2939)
- Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton (2004) (2637)
- Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals (1994) (2268)
- PRDM16 controls a brown fat/skeletal muscle switch (2008) (2115)
- Histone demethylation by a family of JmjC domain-containing proteins (2006) (1971)
- Role of histone H2A ubiquitination in Polycomb silencing (2004) (1680)
- Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. (2002) (1629)
- DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA (2007) (1483)
- RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs (1994) (1443)
- Protein S-nitrosylation: a physiological signal for neuronal nitric oxide (2001) (1395)
- Phosphorylation and Functional Inactivation of TSC2 by Erk Implications for Tuberous Sclerosisand Cancer Pathogenesis (2005) (1272)
- TLR signaling augments macrophage bactericidal activity through mitochondrial ROS (2011) (1240)
- Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. (1999) (1201)
- Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death* (1999) (1089)
- Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. (1998) (1063)
- MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex (1999) (957)
- GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. (2003) (956)
- Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. (2004) (852)
- Histone Deimination Antagonizes Arginine Methylation (2004) (839)
- Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain (2002) (823)
- JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor (2006) (797)
- Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor (2001) (787)
- The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism (1997) (784)
- IκB-β regulates the persistent response in a biphasic activation of NF-κB (1995) (773)
- Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex (1999) (761)
- Differential exoprotease activities confer tumor-specific serum peptidome patterns. (2005) (730)
- RSC, an Essential, Abundant Chromatin-Remodeling Complex (1996) (721)
- Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression (2007) (716)
- A Human Telomeric Protein (1995) (703)
- NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN (2007) (657)
- The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36 (2006) (647)
- Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein (1993) (622)
- Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex (1997) (614)
- An iron delivery pathway mediated by a lipocalin. (2002) (598)
- Conversion of Proepithelin to Epithelins Roles of SLPI and Elastase in Host Defense and Wound Repair (2002) (595)
- COMPASS: A complex of proteins associated with a trithorax-related SET domain protein (2001) (594)
- Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. (2002) (579)
- Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. (2007) (578)
- Human SWI/SNF-Associated PRMT5 Methylates Histone H3 Arginine 8 and Negatively Regulates Expression of ST7 and NM23 Tumor Suppressor Genes (2004) (574)
- Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. (2002) (554)
- PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. (2002) (548)
- Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. (2001) (527)
- The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101 (1997) (527)
- Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. (2006) (524)
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (2005) (521)
- FK506 binding protein associated with the calcium release channel (ryanodine receptor). (1992) (513)
- Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation. (1999) (498)
- PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. (2007) (484)
- A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. (1999) (483)
- Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. (2008) (454)
- The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase (2007) (432)
- A Drosophila Polycomb group complex includes Zeste and dTAFII proteins (2001) (413)
- SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation (2007) (411)
- A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system. (1998) (411)
- PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox (2001) (410)
- Siah2 Regulates Stability of Prolyl-Hydroxylases, Controls HIF1α Abundance, and Modulates Physiological Responses to Hypoxia (2004) (406)
- The Core of the Polycomb Repressive Complex Is Compositionally and Functionally Conserved in Flies and Humans (2002) (405)
- Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival* (1999) (401)
- Function in protein folding of TRiC, a cytosolic ring complex containing TCP‐1 and structurally related subunits. (1992) (400)
- Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like Protein (2002) (377)
- Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases (1999) (366)
- Protein folding in the central cavity of the GroEL–GroES chaperonin complex (1996) (364)
- Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR7 and RXRa (1994) (347)
- Interleukin‐3 signals through multiple isoforms of Stat5. (1995) (341)
- Hematopoiesis Controlled by Distinct TIF1γ and Smad4 Branches of the TGFβ Pathway (2006) (340)
- Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity* (1999) (333)
- Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. (2009) (332)
- mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. (2003) (330)
- L3MBTL1, a Histone-Methylation-Dependent Chromatin Lock (2007) (329)
- Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. (2004) (326)
- A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae (2000) (322)
- The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. (1998) (318)
- Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. (1998) (315)
- Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific Methyltransferase (2002) (311)
- Regulation of cell cycle progression and gene expression by H2A deubiquitination (2007) (308)
- Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. (2002) (306)
- The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism. (1997) (305)
- SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. (1998) (302)
- A CK2-Dependent Mechanism for Degradation of the PML Tumor Suppressor (2006) (298)
- A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. (2007) (282)
- Mesenchymal to Epithelial Conversion in Rat Metanephros Is Induced by LIF (1999) (277)
- HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation (2008) (277)
- The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila (2002) (276)
- mSin3A/Histone Deacetylase 2- and PRMT5-Containing Brg1 Complex Is Involved in Transcriptional Repression of the Myc Target Gene cad (2003) (273)
- Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus (2010) (272)
- Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo (2002) (271)
- LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs (2012) (265)
- Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14 (2004) (257)
- Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin* (2000) (256)
- Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. (2011) (255)
- WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase (2009) (254)
- A Rad26–Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage (2002) (254)
- Proteolytic Cleavage of MLL Generates a Complex of N- and C-Terminal Fragments That Confers Protein Stability and Subnuclear Localization (2003) (253)
- Multiple Mechanisms Confining RNA Polymerase II Ubiquitylation to Polymerases Undergoing Transcriptional Arrest (2005) (247)
- PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. (2005) (246)
- The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene. (1993) (245)
- Purification and Characterization of the Human Elongator Complex* (2002) (242)
- P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. (2002) (240)
- Heterogeneous Fatty Acylation of Src Family Kinases with Polyunsaturated Fatty Acids Regulates Raft Localization and Signal Transduction* (2001) (238)
- Role of the Sin3-Histone Deacetylase Complex in Growth Regulation by the Candidate Tumor Suppressor p33ING1 (2002) (236)
- Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. (2006) (236)
- MTERF3 Is a Negative Regulator of Mammalian mtDNA Transcription (2007) (234)
- The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. (1997) (232)
- A new role for Nogo as a regulator of vascular remodeling (2004) (230)
- MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. (2011) (228)
- Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. (1999) (226)
- The human PAF complex coordinates transcription with events downstream of RNA synthesis. (2005) (222)
- Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. (1999) (222)
- Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB (2009) (222)
- Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. (1998) (219)
- Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide. (1999) (215)
- Brd4 links chromatin targeting to HPV transcriptional silencing. (2006) (212)
- Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates (2001) (212)
- Examination of micro-tip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis. (1998) (206)
- The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases (2008) (205)
- BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanism (2006) (204)
- Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus. (2014) (196)
- A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. (2001) (194)
- The epichaperome is an integrated chaperome network that facilitates tumour survival (2016) (191)
- A novel Rad24 checkpoint protein complex closely related to replication factor C (2000) (190)
- Role of hPHF1 in H3K27 Methylation and Hox Gene Silencing (2007) (190)
- The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor (1994) (189)
- P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac (2002) (187)
- Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase. (1997) (186)
- Co-translational domain folding as the structural basis for the rapid de novo folding of firefly luciferase (1999) (186)
- An Ikaros-Containing Chromatin-Remodeling Complex in Adult-Type Erythroid Cells (2000) (185)
- Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity. (2008) (180)
- RNA Polymerase II Elongator Holoenzyme Is Composed of Two Discrete Subcomplexes* (2001) (178)
- A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK (1996) (178)
- A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells. (1999) (170)
- A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast* (2002) (166)
- WSTF regulates the function of H2A.X via a novel tyrosine kinase activity (2008) (163)
- Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. (2007) (162)
- I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B. (1995) (156)
- S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense. (2005) (156)
- PRC2 Complexes with JARID2, MTF2, and esPRC2p48 in ES Cells to Modulate ES Cell Pluripotency and Somatic Cell Reprograming (2011) (149)
- L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure. (2011) (145)
- Induction of Terminal Differentiation in Epithelial Cells Requires Polymerization of Hensin by Galectin 3 (2000) (144)
- Requirement of a corepressor for Dr1-mediated repression of transcription. (1996) (139)
- Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. (1994) (139)
- Adhesion signaling by a novel mitotic substrate of src kinases (2005) (131)
- The Yaf9 Component of the SWR1 and NuA4 Complexes Is Required for Proper Gene Expression, Histone H4 Acetylation, and Htz1 Replacement near Telomeres (2004) (125)
- Catalytic Properties of ADAM19* (2003) (124)
- ASAP, a Novel Protein Complex Involved in RNA Processing and Apoptosis (2003) (123)
- T‐loop phosphorylation stabilizes the CDK7–cyclin H–MAT1 complex in vivo and regulates its CTD kinase activity (2001) (120)
- The Oms66 (p66) protein is a Borrelia burgdorferi porin (1997) (120)
- Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines (2011) (119)
- Architecture of the Mediator head module (2011) (116)
- Metazoan Scc4 Homologs Link Sister Chromatid Cohesion to Cell and Axon Migration Guidance (2006) (115)
- The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase (2007) (113)
- FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments. (2001) (110)
- Nab2p and the Thp1p-Sac3p Complex Functionally Interact at the Interface between Transcription and mRNA Metabolism* (2003) (109)
- Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros. (1999) (108)
- CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis (2006) (107)
- Myoferlin Regulates Vascular Endothelial Growth Factor Receptor-2 Stability and Function* (2007) (104)
- Human Mob Proteins Regulate the NDR1 and NDR2 Serine-Threonine Kinases* (2004) (103)
- Demethylation of Histone H3K36 and H3K9 by Rph1: a Vestige of an H3K9 Methylation System in Saccharomyces cerevisiae? (2007) (102)
- Helix pomatia Lectin, an Inducer of Drosophila Immune Response, Binds to Hemomucin, a Novel Surface Mucin* (1996) (101)
- Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex. (2006) (100)
- Activated ADP-ribosylation Factor Assembles Distinct Pools of Actin on Golgi Membranes* (2000) (100)
- The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway. (2005) (100)
- Heterogeneous Nuclear Ribonucleoprotein L Is a Subunit of Human KMT3a/Set2 Complex Required for H3 Lys-36 Trimethylation Activity in Vivo* (2009) (100)
- Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection. (1998) (96)
- Mycobacterium tuberculosis appears to lack α‐ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes (2005) (95)
- NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney disease. (2012) (95)
- Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles (2005) (95)
- Isolation and mass spectrometry of transcription factor complexes. (2002) (95)
- RETRACTED: ATP Hydrolysis-Dependent Disassembly of the 26S Proteasome Is Part of the Catalytic Cycle (2005) (92)
- USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing. (2013) (92)
- Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching. (1999) (92)
- Mapping of Amino Acid Residues in the p34 Subunit of Human Single-stranded DNA-binding Protein Phosphorylated by DNA-dependent Protein Kinase and Cdc2 Kinase in Vitro * (1997) (90)
- Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome (2021) (89)
- Identification of a putative effector protein for rab11 that participates in transferrin recycling. (1999) (89)
- Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD (2007) (88)
- Enteric β-Defensin: Molecular Cloning and Characterization of a Gene with Inducible Intestinal Epithelial Cell Expression Associated with Cryptosporidium parvumInfection (1998) (87)
- Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes (2011) (87)
- Processing of autophagic protein LC3 by the 20S proteasome (2010) (84)
- Identification and Functional Characterization of the p66/p68 Components of the MeCP1 Complex (2002) (82)
- Unique Transcriptional Programs Identify Subtypes of AKI. (2017) (82)
- The H3K4 Demethylase Lid Associates with and Inhibits Histone Deacetylase Rpd3 (2008) (82)
- MTERF2 is a nucleoid component in mammalian mitochondria. (2009) (81)
- Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein. (2013) (78)
- Proteasome-Mediated Processing of Def1, a Critical Step in the Cellular Response to Transcription Stress (2013) (78)
- Methodical analysis of protein-nitrocellulose interactions to design a refined digestion protocol. (1996) (77)
- PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex. (2013) (77)
- Merlin / NF 2 Suppresses Tumorigenesis by Inhibiting the E 3 Ubiquitin Ligase CRL 4 DCAF 1 in the Nucleus (2010) (76)
- Biodiversity of apidaecin-type peptide antibiotics. Prospects of manipulating the antibacterial spectrum and combating acquired resistance. (1994) (74)
- Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3. (2008) (73)
- Parkinson's Disease-associated α-Synuclein Is a Calmodulin Substrate* (2003) (72)
- Enteric β-Defensin: Molecular Cloning and Characterization of a Gene with Inducible Intestinal Epithelial Cell Expression Associated with Cryptosporidium parvumInfection (1998) (71)
- The RSC Chromatin Remodeling Complex Bears an Essential Fungal-Specific Protein Module With Broad Functional Roles (2006) (70)
- A Multiprotein Complex That Interacts with RNA Polymerase II Elongator* (2001) (70)
- The Histone Chaperone TAF-I/SET/INHAT Is Required for Transcription In Vitro of Chromatin Templates (2005) (69)
- Improvements in Microsequencer Performance for Low Picomole Sequence Analysis (1994) (69)
- Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1 (2012) (68)
- Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies. (2013) (68)
- A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination. (2005) (68)
- The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein* (2000) (67)
- Microbore reversed-phase high-performance liquid chromatographic purification of peptides for combined chemical sequencing-laser-desorption mass spectrometric analysis. (1994) (66)
- Identification of Rox3 as a Component of Mediator and RNA Polymerase II Holoenzyme* (1997) (66)
- Cytosol‐derived proteins are sufficient for Arp2/3 recruitment and ARF/coatomer‐dependent actin polymerization on Golgi membranes (2004) (66)
- A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila (2019) (60)
- Identification of New Mediator Subunits in the RNA Polymerase II Holoenzyme from Saccharomyces cerevisiae * (1998) (59)
- Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi (1996) (59)
- Components of the Protein Synthesis and Folding Machinery Are Induced in Vascular Smooth Muscle Cells by Hypertrophic and Hyperplastic Agents (1995) (59)
- Fas-associated Death Domain (FADD) and the E3 Ubiquitin-Protein Ligase TRIM21 Interact to Negatively Regulate Virus-induced Interferon Production* (2010) (55)
- Regulation of 2-Oxoglutarate (α-Ketoglutarate) Dehydrogenase Stability by the RING Finger Ubiquitin Ligase Siah* (2004) (55)
- Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma (2017) (55)
- Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1) (1995) (54)
- Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs (2012) (53)
- Mutual Targeting of Mediator and the TFIIH Kinase Kin28* (2004) (53)
- High‐Sensitivity sequencing of large proteins: Partial structure of the rapamycin‐fkbp12 target (1994) (52)
- The Hsp70-Ydj1 Molecular Chaperone Represses the Activity of the Heme Activator Protein Hap1 in the Absence of Heme (2001) (49)
- ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi (1997) (48)
- TRIM3, a tumor suppressor linked to regulation of p21Waf1/Cip1 (2013) (48)
- Parkinson's disease-associated alpha-synuclein is a calmodulin substrate. (2003) (47)
- DAPP1 undergoes a PI 3-kinase-dependent cycle of plasma-membrane recruitment and endocytosis upon cell stimulation (2000) (47)
- A novel Rad24 checkpoint protein complex closely related to replication factor C (2000) (47)
- Phosphorylation of Thyroid Hormone Receptor-associated Nuclear Receptor Corepressor Holocomplex by the DNA-dependent Protein Kinase Enhances Its Histone Deacetylase Activity* (2007) (47)
- Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei * (2000) (46)
- Revised Subunit Structure of Yeast Transcription Factor IIH (TFIIH) and Reconciliation with Human TFIIH* (2003) (43)
- Cyclin A-dependent Phosphorylation of the ETS-related Protein, MEF, Restricts Its Activity to the G1 Phase of the Cell Cycle* (2001) (42)
- The yeast capping enzyme represses RNA polymerase II transcription. (2002) (42)
- Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells (2006) (41)
- The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form (2017) (39)
- Metal chelates as reversible stains for detection of electroblotted proteins: application to protein microsequencing and immunoblotting. (1994) (39)
- Merlin/NF2 Functions Upstream of the Nuclear E3 Ubiquitin Ligase CRL4DCAF1 to Suppress Oncogenic Gene Expression (2011) (39)
- Physical and Functional Interaction between Elongator and the Chromatin-associated Kti12 Protein* (2005) (39)
- Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart. (1992) (37)
- The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction (2020) (37)
- PR-Set 7 Is a Nucleosome-Specific Methyltransferase that Modifies Lysine 20 of Histone H 4 and Is Associated with Silent (2002) (36)
- A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta-class of GSTs. (1994) (34)
- Photoaffinity Labeling and Mass Spectrometry Identify Ribosomal Protein S3 as a Potential Target for Hybrid Polar Cytodifferentiation Agents* (1999) (32)
- Schizosaccharomyces pombe Carboxyl-terminal Domain (CTD) Phosphatase Fcp1 (2004) (32)
- A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation. (2011) (32)
- PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation (2019) (31)
- Monoubiquitination of Filamin B Regulates Vascular Endothelial Growth Factor-Mediated Trafficking of Histone Deacetylase 7 (2013) (31)
- Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells (2011) (30)
- SETDB1 Is Involved in Postembryonic DNA Methylation and Gene Silencing in Drosophila (2010) (29)
- The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation (2003) (29)
- Extramitochondrial cardiolipin suggests a novel function of mitochondria in spermatogenesis (2019) (28)
- Ubiquitylation of histone H 2 B controls RNA polymerase II transcription elongation independently of histone H 3 methylation (2007) (27)
- The laminin receptor modulates granulocyte–macrophage colony-stimulating factor receptor complex formation and modulates its signaling (2003) (27)
- The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function (2003) (27)
- Cleavage and proteasome‐mediated degradation of the basal transcription factor TFIIA (2004) (27)
- HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons (2018) (26)
- Genome-Wide Dynamics of SAPHIRE, an Essential Complex for Gene Activation and Chromatin Boundaries (2007) (25)
- Sample Preparation for Relative Quantitation of Proteins Using Tandem Mass Tags (TMT) and Mass Spectrometry (MS). (2018) (24)
- Role of integrins in the assembly and function of hensin in intercalated cells. (2008) (24)
- The overlapping host responses to bacterial cyclic dinucleotides. (2012) (24)
- Sequence analysis and recombinant expression of a 28-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp2) (1997) (22)
- Erratum: Enteric β-defensin: Molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection (Infection and Immunity 66:3 (1045)) (1998) (22)
- Phagocytosis in Macrophages Lacking Cbl Reveals an Unsuspected Role for Fcγ Receptor Signaling and Actin Assembly in Target Binding1 (2009) (22)
- The Novel Ubiquitin Ligase Complex, SCFFbxw4, Interacts with the COP9 Signalosome in an F-Box Dependent Manner, Is Mutated, Lost and Under-Expressed in Human Cancers (2013) (22)
- Quantitative Comparison of Proteomes Using SILAC (2018) (21)
- Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer (2014) (20)
- Peptide selection by an MHC H-2Kb class I molecule devoid of the central anchor ("C") pocket. (1998) (20)
- Demethylation of Histone H 3 K 36 and H 3 K 9 by Rph 1 : a Vestige of an H 3 K 9 Methylation System in Saccharomyces cerevisiae ? (2007) (19)
- Sequence analysis and characterization of a 40-kilodalton Borrelia hermsii glycerophosphodiester phosphodiesterase homolog (1997) (19)
- EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer (2017) (19)
- Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. (2020) (19)
- JAMP optimizes ERAD to protect cells from unfolded proteins. (2008) (18)
- Monomeric neutrophil gelatinase associated lipocalin is associated with tubulointerstitial damage in chronic kidney disease (2012) (18)
- The Histone Variant MacroH2A1 Regulates Target Gene Expression in Part by Recruiting the Transcriptional Coregulator PELP1 (2014) (16)
- Successful Peptide Sequencing With Femtomole Level PTH-Analysis: A Commentary (1993) (16)
- Lipidome-wide 13C flux analysis: a novel tool to estimate the turnover of lipids in organisms and cultures (2019) (16)
- Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome (2019) (16)
- Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation (2020) (16)
- CHMP 5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis (2006) (15)
- A Direct Interaction between the RAG 2 C Terminus and the Core Histones Is Required for Efficient V ( D ) J Recombination (2005) (14)
- MUC-6 mucin is a major component of "blood group substance" from human ovarian cyst fluid. (2000) (13)
- PU.1 and a TTTAAA Element in the Myeloid Defensin-1 Promoter Create an Operational TATA Box That Can Impose Cell Specificity onto TFIID Function1 (2006) (12)
- High-level expression of a full-length Eph receptor. (2013) (11)
- Abstract 3029: Biochemical evidence towards the existence of an oncogenic Hsp90 complex (2012) (10)
- Catalytic properties of ADAM 19 (2003) (10)
- Aminopeptidase activities as prospective urinary biomarkers for bladder cancer (2014) (10)
- N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis. (2016) (9)
- NGAL ( Lcn 2 ) monomer is associated with tubulointerstitial damage in chronic kidney disease (2012) (9)
- Serine phosphorylation regulates the P-type potassium pump KdpFABC (2020) (9)
- A novel requirement for DROSHA in maintenance of mammalian CG methylation (2017) (8)
- Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer’s disease mouse model (2020) (8)
- Cardiolipin remodeling enables protein crowding in the inner mitochondrial membrane (2021) (8)
- Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons (2019) (7)
- MALDI-TOF Mass Spectrometry in the Protein Biochemistry Lab: From Characterization of Cell Cycle Regulators to the Quest for Novel Antibiotics (1996) (7)
- The Hsp 70-Ydj 1 Molecular Chaperone Represses the Activity of the Heme Activator Protein Hap 1 in the Absence of Heme (2008) (5)
- Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer (2021) (5)
- Two Actin-Related Proteins Are Shared Functional (1998) (5)
- Sequence Analysis and Recombinant Expression of a 28-Kilodalton Treponema pallidum subsp . pallidum Rare Outer Membrane Protein ( Tromp 2 ) † (1997) (4)
- Lipidome-wide 13C flux analysis: a novel tool to estimate the turnover of lipids in organisms and cultures. (2020) (4)
- Physical and Functional Interaction between Elongator and the Chromatin-associated Kti 12 Protein * (2005) (3)
- Characterizing proteins from 2-DE gels by internal sequence analysis of peptide fragments. Strategies for microsample handling. (1999) (3)
- Sex-Specific Differences in Oxytocin Receptor Expression and Function for Parental Behavior (2017) (3)
- Regulation of post-Golgi vesicle production in an in vitro system. (1995) (3)
- Lysosomal dysfunction in Down Syndrome and Alzheimer mouse models is caused by selective v-ATPase inhibition by Tyr682 phosphorylated APP βCTF (2023) (2)
- Role of H2A deubiquitination in cell cycle progression and Hox gene expression (2007) (2)
- Dysregulation of the de novo proteome accompanies pathology progression in the APP/PS1 mouse model of Alzheimer’s disease (2020) (2)
- Erratum: COMPASS: A complex of proteins associated with a trithorax-related SET domain protein (Proceedings of the National Academy of Sciences of the United States of America (November 6, 2001) 98:23 (112902-12907)) (2001) (1)
- Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signaling (2021) (1)
- Cocaine perturbs mitovesicle biology in the brain (2023) (1)
- Condensed Mitochondria Assemble Into the Acrosomal Matrix During Spermiogenesis (2022) (1)
- Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer’s disease mouse model (2021) (1)
- Supplemental Data JHDM2A, a JmjC Domain-Containing H3K9 Demethylase, Facilitates Transcriptional Activation by Androgen Receptor (2006) (0)
- A CK2-Dependent Mechanism for PML Degradation upon Cellular and Oncogenic Stress. (2006) (0)
- The functional association between filamin B (FLNB) and histone deacetylase 7 (HDAC7) in endothelial cells (ECs) (2011) (0)
- Retraction Notice to: ATP Hydrolysis-Dependent Disassembly of the 26S Proteasome Is Part of the Catalytic Cycle (2018) (0)
- Structure of AhpD from Mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity. (2002) (0)
- Abstract 5463: YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells (2010) (0)
- PTK7 is a positive allosteric modulator of GPR133 (ADGRD1) signaling in GBM (2022) (0)
- The Ubiquitination of PINK 1 Is Restricted to Its Mature 52-kDa Form Graphical Abstract Highlights (2017) (0)
- PocketMolecule Devoid of the Central Anchor (''C'') Class I b Peptide Selection by an MHC H-2K (1998) (0)
- Knockout of cardiolipin synthase disrupts postnatal cardiac development by inhibiting the maturation of mitochondrial cristae (2023) (0)
- P99-T A Simple Method to Quantitate Selenomethionine Incorporation into Proteins (2007) (0)
- taylor tempst PRCA2014.Supplementary (2015) (0)
- Abstract 437: Novel function of the BAP1 nuclear deubiquitinase in the non-homologous end joining (NHEJ) pathway of double strand DNA repair (2014) (0)
- Signalling via PI3-kinases (2001) (0)
- CSIG-21. DE-ORPHANIZING GPR133 - AN ADHESION GPCR REQUIRED FOR GLIOBLASTOMA PROGRESSION (2019) (0)
- Abstract 2579: YK5, a small molecule inhibitor of Hsp70 and Hsc70, reveals a multifaceted role for the Hsp70 chaperones in regulating oncogenic and non-oncogenic addiction of tumors (2011) (0)
- Protein Micro-Characterization by Mass Spectrometry: Sample Handling and Data Flow (2000) (0)
- A novel requirement for DROSHA in maintenance of mammalian CG methylation (2017) (0)
- Adipocyte-specif ic transcription factor ARF6isa heterodimeric complex oftwonuclear hormone receptors, PPARyandRXRoe (1994) (0)
- , cad the Myc Target Gene Involved in Transcriptional Repression of PRMT 5-Containing Brg 1 Complex Is mSin 3 A / Histone Deacetylase 2-and (2003) (0)
- Abstract 1032: Identification of Ran binding protein 6 as a novel negative regulator of EGFR and candidate tumor suppressor in glioblastoma (2017) (0)
- Understanding the molecular composition of the microsporidian polar tube. (2023) (0)
- Processing of the Ubiquitin‐like Autophagic Protein LC3 by the 20S Proteasome (2010) (0)
- HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons (2018) (0)
- Abstract 1263: Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 (2012) (0)
- and Htz1 Replacement near Telomeres Gene Expression, Histone H4 Acetylation, NuA4 Complexes Is Required for Proper The Yaf9 Component of the SWR1 and (2014) (0)
- burgdorferi.membrane protein Oms28 of Borrelia Porin activity of the native and recombinant (2013) (0)
- Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells (2015) (0)
- gammaherpesvirus-associated malignancies Targeting the Hsp90-associated viral oncoproteome in (2013) (0)
- Retraction: SETDB1 Is Involved in Postembryonic DNA Methylation and Gene Silencing in Drosophila (2018) (0)
- EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer (2017) (0)
- Targeting the Hsp90 Oncoproteome in Burkitt Lymphoma (2015) (0)
- Structures of LRP2 reveal a molecular machine for endocytosis (2023) (0)
- Action and Inactivation of the Bacterial Potassium Pump KdpFABC (2020) (0)
- Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1) (2022) (0)
- SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex (2023) (0)
- Heterogeneous Nuclear Ribonucleoprotein L Is a Subunit of Human KMT3a/Set2 Complex Required for H3 Lys-36 (2009) (0)
- The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction (2020) (0)
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