Heinrich Leonhardt
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Physics
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(Suggest an Edit or Addition)Heinrich Leonhardt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Induction of Tumors in Mice by Genomic Hypomethylation (2003) (1193)
- A guide to super-resolution fluorescence microscopy (2010) (1169)
- A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei (1992) (1067)
- Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy (2008) (1063)
- Comparative Analysis of Single-Cell RNA Sequencing Methods. (2017) (940)
- Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives (2013) (893)
- LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation (2013) (654)
- A Versatile Nanotrap for Biochemical and Functional Studies with Fluorescent Fusion Proteins*S (2008) (649)
- Targeting and tracing antigens in live cells with fluorescent nanobodies (2006) (609)
- Dynamics of DNA Replication Factories in Living Cells (2000) (569)
- Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes (2008) (486)
- Modulation of protein properties in living cells using nanobodies (2010) (478)
- Cortical Constriction During Abscission Involves Helices of ESCRT-III–Dependent Filaments (2011) (451)
- Camelid immunoglobulins and nanobody technology. (2009) (445)
- Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA (2010) (432)
- Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication (1993) (396)
- Recruitment of DNA methyltransferase I to DNA repair sites. (2005) (361)
- In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases (2012) (349)
- Heterochromatin drives compartmentalization of inverted and conventional nuclei (2019) (333)
- 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes (2012) (312)
- Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells (2007) (309)
- cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders (2017) (271)
- Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks (2006) (252)
- DNA labeling in living cells (2005) (251)
- Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA. (2014) (242)
- Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation (2007) (239)
- Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation (2005) (232)
- DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. (2002) (220)
- Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers (2012) (198)
- DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells (2007) (196)
- Recognition of 5-Hydroxymethylcytosine by the Uhrf1 SRA Domain (2011) (195)
- DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination (2015) (194)
- Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells (2009) (187)
- Nanobodies and recombinant binders in cell biology (2015) (182)
- Replication‐independent chromatin loading of Dnmt1 during G2 and M phases (2004) (177)
- Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells. (2017) (176)
- BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples (2018) (170)
- p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1 (2016) (164)
- DNA Methyltransferase Is Actively Retained in the Cytoplasm during Early Development (1999) (162)
- The multi-domain protein Np95 connects DNA methylation and histone modification (2009) (156)
- MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation (2007) (153)
- CDK9-dependent RNA polymerase II pausing controls transcription initiation (2017) (152)
- Visualization and targeted disruption of protein interactions in living cells (2013) (152)
- Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci (2014) (150)
- Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system (2014) (148)
- Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1 (2011) (143)
- Interactions within the mammalian DNA methyltransferase family (2003) (139)
- Trapped in action: direct visualization of DNA methyltransferase activity in living cells (2005) (137)
- Functional nuclear organization of transcription and DNA replication: a topographical marriage between chromatin domains and the interchromatin compartment. (2010) (135)
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex (2018) (133)
- Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation. (2017) (127)
- CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin (2012) (125)
- PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins (2005) (124)
- Identification of the elementary structural units of the DNA damage response (2017) (122)
- Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production (2014) (122)
- DNA methylation‐mediated epigenetic control (2009) (121)
- Dnmt1 Expression in Pre- and Postimplantation Embryogenesis and the Maintenance of IAP Silencing (2004) (120)
- Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51–Rad52 interaction (2013) (119)
- Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y (2010) (116)
- PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms (2011) (116)
- Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin. (2013) (114)
- Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1 (2011) (112)
- DNA methylation, nuclear structure, gene expression and cancer (2000) (112)
- Current Status: Site-Specific Antibody Drug Conjugates (2016) (108)
- Mapping and Use of a Sequence that Targets DNA Ligase I to Sites of DNA Replication In Vivo (1997) (106)
- Measurement of replication structures at the nanometer scale using super-resolution light microscopy (2009) (105)
- Stable chromosomal units determine the spatial and temporal organization of DNA replication (2004) (103)
- 4D Visualization of replication foci in mammalian cells corresponding to individual replicons (2016) (102)
- Differential recruitment of DNA Ligase I and III to DNA repair sites (2006) (101)
- Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure. (2000) (101)
- Phosphorylation of TET Proteins Is Regulated via O-GlcNAcylation by the O-Linked N-Acetylglucosamine Transferase (OGT)* (2015) (99)
- Roquin Suppresses the PI3K‐mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells (2017) (96)
- Probing Intranuclear Environments at the Single-Molecule Level (2007) (94)
- H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization (2012) (93)
- Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene. (1996) (92)
- Regulation of DNA methyltransferase 1 by interactions and modifications (2011) (90)
- TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation (2014) (89)
- The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin. (2008) (86)
- Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways (2011) (86)
- A protein assembly mediates Xist localization and gene silencing (2020) (81)
- XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions (2007) (78)
- A Fluorescent Two-hybrid Assay for Direct Visualization of Protein Interactions in Living Cells*S (2008) (77)
- MeCP2 Rett mutations affect large scale chromatin organization. (2011) (76)
- Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin (2008) (74)
- Chemical functionalization strategies and intracellular applications of nanobodies (2017) (74)
- Differentiation and large scale spatial organization of the genome. (2010) (73)
- Nanobodies: Chemical Functionalization Strategies and Intracellular Applications (2018) (70)
- Targeting and tracing of specific DNA sequences with dTALEs in living cells (2013) (69)
- Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase. (2015) (69)
- De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation (2011) (68)
- Universal Super-Resolution Multiplexing by DNA Exchange. (2017) (67)
- Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia (2011) (67)
- Role for hACF1 in the G2/M damage checkpoint (2011) (65)
- A Short DNA Methyltransferase Isoform Restores Methylation In Vivo * (1998) (63)
- Top-down de Novo protein sequencing of a 13.6 kDa camelid single heavy chain antibody by matrix-assisted laser desorption ionization-time-of-flight/time-of-flight mass spectrometry. (2010) (62)
- Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control (2014) (62)
- Structure, function and regulation of mammalian DNA methyltransferase. (1993) (62)
- Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin (2011) (61)
- Dissection of cell cycle–dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling (2013) (61)
- Magnetosome Expression of Functional Camelid Antibody Fragments (Nanobodies) in Magnetospirillum gryphiswaldense (2011) (61)
- Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver (2018) (60)
- Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen (2006) (59)
- LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells (2018) (58)
- Cell Cycle Markers for Live Cell Analyses (2005) (57)
- Analysis of centriole elimination during C. elegans oogenesis (2012) (57)
- Quantitative 3D structured illumination microscopy of nuclear structures (2017) (56)
- Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia (2017) (55)
- A novel isoform of the smooth muscle cell differentiation marker smoothelin (1999) (55)
- Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation (2020) (54)
- Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina (2013) (54)
- A mammalian myocardial cell-free system to study cell cycle reentry in terminally differentiated cardiomyocytes. (1999) (53)
- Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine (2011) (53)
- Direct and Dynamic Detection of HIV-1 in Living Cells (2012) (51)
- Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain (2009) (51)
- DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution (2014) (50)
- Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association (2019) (50)
- Histone acetylation controls the inactive X chromosome replication dynamics (2011) (50)
- Mammalian DNA methyltransferases show different subnuclear distributions (2001) (50)
- A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies. (2012) (50)
- Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites (2008) (49)
- Loss of KDM6A confers drug resistance in acute myeloid leukemia (2018) (49)
- Determination of local chromatin composition by CasID (2016) (49)
- Construction of a shuttle vector for inducible gene expression in Escherichia coli and Bacillus subtilis. (1988) (48)
- Engineering antibodies and proteins for molecular in vivo imaging. (2011) (47)
- Nucleolar marker for living cells (2007) (46)
- Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network (2016) (45)
- Intrinsic and Extrinsic Connections of Tet3 Dioxygenase with CXXC Zinc Finger Modules (2013) (45)
- FUS-dependent liquid–liquid phase separation is important for DNA repair initiation (2021) (44)
- In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells (2018) (43)
- Nuclear architecture: Is it important for genome function and can we prove it? (2007) (41)
- Cascaded Photoinduced Drug Delivery to Cells from Multifunctional Core–Shell Mesoporous Silica (2012) (41)
- Heterochromatin drives organization of conventional and inverted nuclei (2018) (39)
- Poly(ADP-ribose) Polymerase 1 (PARP1) Associates with E3 Ubiquitin-Protein Ligase UHRF1 and Modulates UHRF1 Biological Functions* (2014) (39)
- Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations. (2019) (39)
- Step-Wise Assembly, Maturation and Dynamic Behavior of the Human CENP-P/O/R/Q/U Kinetochore Sub-Complex (2012) (38)
- Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells. (2017) (38)
- Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation (2017) (38)
- A modular open platform for systematic functional studies under physiological conditions (2015) (37)
- Myb-binding Protein 1a (Mybbp1a) Regulates Levels and Processing of Pre-ribosomal RNA* (2012) (37)
- Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase (2017) (37)
- Small chromosomal regions position themselves autonomously according to their chromatin class. (2017) (36)
- Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma. (2020) (36)
- Global DNA Hypomethylation Prevents Consolidation of Differentiation Programs and Allows Reversion to the Embryonic Stem Cell State (2012) (35)
- Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals (2020) (35)
- MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos (2009) (35)
- Targeting and association of proteins with functional domains in the nucleus: the insoluble solution. (1995) (34)
- Parameters affecting plasmid stability in Bacillus subtilis. (1991) (34)
- Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time (2015) (34)
- Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure* (2016) (33)
- The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. (2013) (33)
- Spatial organization of transcribed eukaryotic genes (2020) (33)
- A unified multi-kingdom Golden Gate cloning platform (2019) (33)
- Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins. (2008) (32)
- Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters (2017) (32)
- The fluorescent two-hybrid (F2H) assay for direct analysis of protein-protein interactions in living cells. (2012) (32)
- Identification and Characterization of Novel Smoothelin Isoforms in Vascular Smooth Muscle (2001) (32)
- DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation (2017) (32)
- Uncoupling the replication machinery: Replication fork progression in the absence of processive DNA synthesis (2008) (32)
- Functional links between nuclear structure, gene expression, DNA replication, and methylation. (1999) (32)
- Novel antibody derivatives for proteome and high-content analysis (2010) (32)
- Expression of an alternative Dnmt1 isoform during muscle differentiation. (2000) (32)
- Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise (2016) (32)
- Case study on live cell apoptosis-assay using lamin-chromobody cell-lines for high-content analysis. (2012) (31)
- Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus (2020) (31)
- KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1 (2016) (31)
- Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS). (2005) (31)
- Replication and translation of epigenetic information. (2006) (30)
- A versatile non-radioactive assay for DNA methyltransferase activity and DNA binding (2009) (30)
- A novel approach to induce cell cycle reentry in terminally differentiated muscle cells (2002) (29)
- Intranuclear targeting of DNA replication factors (1998) (29)
- Direct protein transfer to terminally differentiated muscle cells (1999) (28)
- Regulation and spatial organization of PCNA in Trypanosoma brucei. (2012) (27)
- Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming (2005) (27)
- Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA (2018) (26)
- Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites (2008) (26)
- Tunable light and drug induced depletion of target proteins (2020) (26)
- Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis. (2018) (26)
- Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells (2016) (25)
- Front Cover: N ‐Hydroxysuccinimide‐Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates (ChemBioChem 1‐2/2020) (2020) (25)
- Comparative Analysis of Single-Cell RNA Sequencing Methods (2016) (25)
- Characterization of the sebocyte lipid droplet proteome reveals novel potential regulators of sebaceous lipogenesis. (2015) (25)
- CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells. (2005) (24)
- An Intracellular Nanotrap Redirects Proteins and Organelles in Live Bacteria (2015) (24)
- Diurnality and Nocturnality in Primates: An Analysis from the Rod Photoreceptor Nuclei Perspective (2014) (24)
- Expression in mammalian cells of a cloned gene encoding murine DNA methyltransferase. (1991) (24)
- Structure, function and dynamics of nuclear subcompartments. (2012) (23)
- A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle (2014) (23)
- Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering. (2017) (22)
- Chimeric PD-1:28 Receptor Upgrades Low-Avidity T cells and Restores Effector Function of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy. (2017) (22)
- Ethynylphosphonamidates for the Rapid and Cysteine‐Selective Generation of Efficacious Antibody–Drug Conjugates (2019) (22)
- Regulation of DNA methyltransferase 1. (2006) (22)
- Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies (2011) (21)
- Protein targeting to subnuclear higher order structures: A new level of regulation and coordination of nuclear processes (1998) (21)
- Twists and turns of DNA methylation (2011) (21)
- Generation and characterization of a rat monoclonal antibody specific for PCNA. (2008) (21)
- Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections (2012) (21)
- Binding of the Heterogeneous Ribonucleoprotein K (hnRNP K) to the Epstein-Barr Virus Nuclear Antigen 2 (EBNA2) Enhances Viral LMP2A Expression (2012) (21)
- Cohesin depleted cells rebuild functional nuclear compartments after endomitosis (2019) (20)
- L1 retrotransposition is activated by Ten-eleven-translocation protein 1 and repressed by methyl-CpG binding proteins (2017) (19)
- Smoothelin contains a novel actin cytoskeleton localization sequence with similarity to troponin T (2002) (18)
- Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans (2019) (18)
- Identification of a low-copy-number mutation within the pUB110 replicon and its effect on plasmid stability in Bacillus subtilis. (1990) (18)
- Functional analysis of the leading strand replication origin of plasmid pUB110 in Bacillus subtilis. (1988) (17)
- The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation (2021) (17)
- Distribution of DNA replication proteins in Drosophila cells (2007) (17)
- Generation of an alpaca-derived nanobody recognizing γ-H2AX (2015) (16)
- Controlling The Mobility Of Oligonucleotides In The Nanochannels Of Mesoporous Silica (2012) (16)
- EGFR/ERBB receptors differentially modulate sebaceous lipogenesis (2015) (15)
- Synthesis of DNA dumbbell based inhibitors for the human DNA methyltransferase Dnmt1. (2008) (15)
- Structure and function in the nucleus: Subnuclear trafficking of DNA replication factors (1999) (15)
- FLEXamers: A Double Tag for Universal Generation of Versatile Peptide-MHC Multimers (2019) (14)
- Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair (2019) (14)
- Fluorescent protein specific Nanotraps to study protein-protein interactions and histone-tail peptide binding. (2012) (13)
- Cristae-dependent quality control of the mitochondrial genome (2021) (12)
- Physical and biochemical characterization of recombination-dependent synthesis of linear plasmid multimers in Bacillus subtilis. (1991) (12)
- Identification and characterization of two novel primate-specific histone H 3 variants , H 3 . X and H 3 . Y (12)
- Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML (2021) (11)
- Immunofluorescence techniques in cell cycle studies (1996) (11)
- Energy profile of nanobody–GFP complex under force (2015) (11)
- Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency (2018) (10)
- Targeting regulatory factors to intranuclear replication sites. (2000) (10)
- An Unexpected Link Between Energy Metabolism, Calcium, Chromatin Condensation and Cell Cycle (2007) (10)
- N‐Hydroxysuccinimide‐Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates (2020) (10)
- A mutagenesis strategy combining systematic alanine scanning with larger mutations to study protein interactions. (2008) (9)
- Protein Transduction: A Novel Tool for Tissue Regeneration (2002) (9)
- Developmental differences in genome replication program and origin activation (2020) (9)
- CRISPR‐assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes (2017) (9)
- Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads (2020) (9)
- Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer (2020) (8)
- Parallel Force Assay for Protein-Protein Interactions (2014) (8)
- The CENP-T C-Terminus Is Exclusively Proximal to H3.1 and not to H3.2 or H3.3 (2015) (8)
- Differentiation, development and programmed cell death (1999) (8)
- Lipids and function of etiochloroplasts after ultraviolet, blue and red light-illumination. (1977) (8)
- Intranuclear targeting of DNA replication factors. (1998) (8)
- Synthesis and Functionalization of Ordered Large-Pore Mesoporous Silica Nanoparticles for Biomedical Applications (2017) (7)
- Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency (2021) (7)
- FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair (2019) (7)
- Visualization of Genomic Loci in Living Cells with a Fluorescent CRISPR/Cas9 System. (2016) (7)
- An Xist-dependent protein assembly mediates Xist localization and gene silencing (2020) (7)
- Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress (2021) (6)
- IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network. (2022) (6)
- TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation (2022) (6)
- HP1β carries an acidic linker domain and requires H3K9me3 for phase separation (2021) (6)
- Nanoparticle mediated delivery and small molecule triggered activation of proteins in the nucleus (2018) (6)
- TuPPL: Tub-tag mediated C-terminal protein-protein-ligation using complementary click-chemistry handles. (2019) (6)
- Cohesin depleted cells pass through mitosis and reconstitute a functional nuclear architecture (2019) (5)
- Publisher Correction: Heterochromatin drives compartmentalization of inverted and conventional nuclei (2019) (5)
- A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies (2016) (5)
- Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells (2020) (5)
- Restriction of AID activity and somatic hypermutation by PARP-1 (2019) (5)
- Tubulin Tyrosine Ligase-Mediated Modification of Proteins. (2019) (5)
- TET1 drives global DNA demethylation via DPPA3-mediated inhibition of maintenance methylation (2018) (5)
- Visualization and Measurement of DNA Methyltransferase Activity in Living Cells (2008) (4)
- Author response: CDK9-dependent RNA polymerase II pausing controls transcription initiation (2017) (4)
- Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals (2020) (4)
- S1 mapping of the pC194 encoded chloramphenicol acetyltransferase gene in Bacillus subtilis. (1988) (4)
- Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci (2014) (4)
- recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen (2006) (3)
- Synthese von hantelförmigen DNA‐Inibitoren für die humane DNA‐Methyltransferase Dnmt1 (2008) (3)
- Generation of an alpaca-derived nanobody recognizing c-H 2 AX (2015) (3)
- Heterochromatin drives compartmentalization of inverted and conventional nuclei (2019) (3)
- Targeting and Tracing of Antigens in Living Cells with Fluorescent Nanobodies (2007) (3)
- Poly(ADP-ribosyl)ation of methyl CpG binding protein 2 regulates chromatin structure. (2016) (3)
- Visualization and characterization of RNA–protein interactions in living cells (2021) (2)
- MeCP2-induced heterochromatin organization is driven by oligomerization-based liquid–liquid phase separation and restricted by DNA methylation (2022) (2)
- Tub-Tag Labeling; Chemoenzymatic Incorporation of Unnatural Amino Acids. (2018) (2)
- 361 GROWTH HORMONE RECEPTOR MUTANT PIGS PRODUCED BY USING THE CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR) AND CRISPR-ASSOCIATED SYSTEMS IN IN VITRO-PRODUCED ZYGOTES (2015) (2)
- Deciphering the regulatory logic of a Drosophila enhancer through systematic sequence mutagenesis and quantitative image analysis (2020) (2)
- MBD 4 and MLH 1 are required for apoptotic induction in xDNMT 1-depleted embryos (2009) (2)
- A Short DNA Methyltransferase Isoform Restores Methylation (1998) (2)
- Histone glutamine methylation afFACTing rDNA transcription (2014) (2)
- Linker Molecules Convert Commercial Fluorophores into Tailored Functional Probes during Biolabelling (2022) (2)
- Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy (2020) (2)
- Locus-Specific Chromatin Proteome Revealed by Mass Spectrometry-Based CasID. (2020) (2)
- Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm (2022) (2)
- KDM 2 A integrates DNA and histone modification signals through a CXXC / PHD module and direct interaction with HP 1 (2016) (1)
- DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution (2014) (1)
- Photo-induced Drug Delivery: Cascaded Photoinduced Drug Delivery to Cells from Multifunctional Core–Shell Mesoporous Silica (Adv. Healthcare Mater. 3/2012) (2012) (1)
- Studies of Mechanisms Controlling Dna Methyltransferase 1 Studies of Mechanisms Controlling Dna Methyltransferase 1 (1)
- LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells (2018) (1)
- POSTER VIEWING SESSION - REPRODUCTIVE ENDOCRINOLOGY (2011) (1)
- TARGETING FLT3 BY NEW-GENERATION ANTIBODY-DRUG-CONJUGATE IN COMBINATION WITH KINASE INHIBITORS FOR TREATMENT OF AML. (2022) (1)
- Camel antibodies for therapeutic and research applications. (2007) (1)
- Crystal structure of the N-terminal domain of HIV-1 capsid in complex with an assembly-inhibiting nanobody (2011) (1)
- Fluorescence microscopy-based high-throughput screening for factors involved in gene silencing. (2013) (1)
- 2. DNA Methylation (2011) (1)
- CPT 1 a over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293 T cells q (2005) (1)
- Investigation of Dnmt1-DNA Interaction using Fluorescence Fluctuation Spectroscopy (2009) (1)
- Tyrosin Kinase Inhibition Restores the Membrane Localization of FLT3-ITD (2015) (1)
- Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger (2022) (1)
- Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation (2020) (1)
- Biomedical Applications: Controlling The Mobility Of Oligonucleotides In The Nanochannels Of Mesoporous Silica (Adv. Funct. Mater. 1/2012) (2012) (1)
- Differences in nanoscale organization of regulatory active and inactive human chromatin (2022) (1)
- Green fluorescent protein bound to enhancer nanobody (2009) (1)
- Tunable light and drug induced depletion of target proteins (2020) (0)
- Lothar Schermelleh , Microscopy Periphery with 3 D Structured Illumination Subdiffraction Multicolor Imaging of the Nuclear (2008) (0)
- Live-cell imaging reveals dynamics and distribution of Tet1 in mouse embryonic stem cells (2016) (0)
- Comparative Analysis of S ingle-Cell RNA Sequencing Methods Graphical (2017) (0)
- 543-Pos Board B422 Probing Nucleocytoplasmic Transport with Fluorescence Fluctuation Spectroscopy and Two-photon Activation of Photoactivable GFP (2009) (0)
- Diurnality and Nocturnality in Primates: An Analysis from the Rod Photoreceptor Nuclei Perspective (2013) (0)
- Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 231) in complex with a camelid VHH. (2011) (0)
- Lothar Schermelleh Structured Illumination Microscopy Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3 D (2012) (0)
- KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1. (2016) (0)
- Green fluorescent protein bound to minimizer nanobody (2009) (0)
- Maintenance of IAP Silencing Postimplantation Embryogenesis and the Dnmt 1 Expression in Pre-and (2004) (0)
- Replisome loading reduces chromatin motion independent of DNA synthesis (2023) (0)
- Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation (2021) (0)
- Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and <italic>C. elegans</italic> (2019) (0)
- Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina (2013) (0)
- Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA (2018) (0)
- Premier Lecture Series (2005) (0)
- Deletion of the ZnF motif does not abolish recruitment of DNA Ligase III (2011) (0)
- olerance of tubulin tyrosine ligase enables one-step site-speci fi c enzymatic protein labeling † (2017) (0)
- Characterization of H 3 K 56 me 3 , a novel histone core modification (2014) (0)
- P04.04 Multifunctional antibody construct for in vivo targeting of dendritic cells as a therapeutic vaccination strategy in AML (2020) (0)
- Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells (2016) (0)
- Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 220) in complex with a camelid VHH. (2011) (0)
- Publisher Correction: A protein assembly mediates Xist localization and gene silencing (2020) (0)
- Discontinous Movement of mRNPs in Nucleoplasmic Regions Devoid of Chromatin (2009) (0)
- JCB_201404160 1..18 (2014) (0)
- Cover Feature: Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy (7/2021) (2021) (0)
- Model for selective targeting of DNA Ligase I and III to DNA replication and different repair pathways (2011) (0)
- Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML. (2023) (0)
- Addressing and monitoring antigens in live cells (2006) (0)
- Heterochromatin organization and phase separation (2023) (0)
- 3034 – CYTOSTATIC STRESS CAUSES DEFECTS IN ACTIN-DEPENDENT AUTOPHAGY OF WNT5A-DELETED STROMAL CELLS (2020) (0)
- Release kinetics of DNA Ligase I and III at DNA repair sites (2011) (0)
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex (2018) (0)
- Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections (2012) (0)
- Crystal structure of the HIV-1 capsid protein C-terminal domain in complex with a camelid VHH and the CAI peptide. (2011) (0)
- Protein therapy: Applications in tissue regeneration and stem cell research (2002) (0)
- Expression of Concern: Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. (2022) (0)
- Crystal structure of a camelid VHH raised against the HIV-1 capsid protein C-terminal domain. (2011) (0)
- Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency (2020) (0)
- A unified multi-kingdom Golden Gate cloning platform (2019) (0)
- Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma (2019) (0)
- P09.03 Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma (2020) (0)
- Probing protein ubiquitination in live cells (2022) (0)
- DNA replication machinery clamps down on chromatin mobility (2011) (0)
- (Recombinant DNA; shuttle vector; cytosine methylation assay; CpG dinucleotides) (2002) (0)
- Functional analysis oftheleading strand replication origin ofplasmid pUBllOinBacillus subtilis (1988) (0)
- Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome (2018) (0)
- The targeting and detection of antigens in live cells (2006) (0)
- Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase (2017) (0)
- Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters (2017) (0)
- P433: ADAPTER HOLIDAYS MAINTAIN IN-VITRO ADCAR-T CELL FUNCTIONALITY AGAINST AML (2022) (0)
- ARID1A Controls a Novel Transcriptional Network Regulating FAS in Follicular Lymphoma (2021) (0)
- Law and order in the nucleus: dynamics of replication factories in living cells (2000) (0)
- Current Status: Site-Specific Antibody Drug Conjugates (2016) (0)
- Effects of selective degradation of the cohesin complex on higher order chromatin structures studied with live cell and super-resolved fluorescence microscopy (2019) (0)
- One-Step Fluorescent Protein Labeling by Tubulin Tyrosine Ligase. (2019) (0)
- Differences in nanoscale organization of DNase I hypersensitive and insensitive chromatin in single human cells (2021) (0)
- Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components (2022) (0)
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What Schools Are Affiliated With Heinrich Leonhardt?
Heinrich Leonhardt is affiliated with the following schools:
