Helen Cooke
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Gastroenterologist and physiology researcher
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Helen Cookemedical Degrees
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Gastroenterology
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Helen Cookebiology Degrees
Biology
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Physiology
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Medical Biology
Helen Cooke's Degrees
- Bachelors Biology University of California, Berkeley
- Doctorate Medicine Stanford University
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Why Is Helen Cooke Influential?
(Suggest an Edit or Addition)According to Wikipedia, Helen J. Cooke was an American gastroenterologist who was a professor at Ohio State University. She studied intestinal mucosa and pioneered the field of neurobiology. Throughout her career, Cooke campaigned to support women and early career researchers.
Helen Cooke's Published Works
Published Works
- Neurobiology of the intestinal mucosa. (1986) (177)
- Neurotransmitters in Neuronal Reflexes Regulating Intestinal Secretion (2000) (148)
- Neuroimmune signaling in regulation of intestinal ion transport. (1994) (129)
- D-glucose releases 5-hydroxytryptamine from human BON cells as a model of enterochromaffin cells. (2001) (123)
- Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system (2001) (123)
- Role for 5-HT and ACh in submucosal reflexes mediating colonic secretion. (1995) (110)
- Neuroimmune communication in the submucous plexus of guinea pig colon after sensitization to milk antigen. (1994) (106)
- Role of the “little brain” in the gut in water and electrolyte homeostasis 1 (1989) (103)
- Neuroimmune communication in the submucous plexus of guinea pig colon after infection with Trichinella spiralis. (1994) (95)
- 5‐HT activates neural reflexes regulating secretion in the guinea‐pig colon (1997) (94)
- Mechanical stimulation activates Galphaq signaling pathways and 5-hydroxytryptamine release from human carcinoid BON cells. (2001) (86)
- Sensory mechanisms: transmitters, modulators and reflexes (2004) (81)
- ADOA3R as a Therapeutic Target in Experimental Colitis: Proof by Validated High‐density Oligonucleotide Microarray Analysis (2006) (80)
- Pharmacological analysis of 5-hydroxytryptamine actions on guinea-pig ileal mucosa. (1985) (77)
- Histamine receptors on submucous neurons in guinea pig colon. (1993) (77)
- "Enteric Tears": Chloride Secretion and Its Neural Regulation. (1998) (76)
- Influence of enteric cholinergic neurons on mucosal transport in guinea pig ileum. (1984) (74)
- Serotonin receptors on submucous neurons in guinea pig colon. (1991) (69)
- Substance P as a mediator of colonic secretory reflexes. (1997) (69)
- Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors (2004) (66)
- Effects of neuronal stimulation on mucosal transport in guinea pig ileum. (1983) (61)
- Potassium transport by rabbit descending colon. (1982) (61)
- Activation of 5-HT1P receptors on submucosal afferents subsequently triggers VIP neurons and chloride secretion in the guinea-pig colon. (1997) (61)
- Histamine augments colonic secretion in guinea pig distal colon. (1990) (59)
- Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon (2004) (58)
- Presence of NK1 receptors on a mucosal-like mast cell line, RBL-2H3 cells. (1998) (58)
- "The force be with you": ATP in gut mechanosensory transduction. (2003) (57)
- Histamine action on guinea pig ileal mucosa. (1984) (57)
- Submucosal reflexes: distension-evoked ion transport in the guinea pig distal colon. (1992) (56)
- Neuroimmune regulation of colonic secretion in guinea pigs. (1991) (51)
- Endogenous adenosine differentially modulates 5-hydroxytryptamine release from a human enterochromaffin cell model. (2004) (50)
- Epithelial responses evoked by stimulation of submucosal neurons in guinea pig distal colon. (1987) (49)
- Rabbit chronic ileitis leads to up-regulation of adenosine A1/A3 gene products, oxidative stress, and immune modulation. (2003) (46)
- Tachykinin-induced anion secretion in guinea pig distal colon: role of neural and inflammatory mediators. (1990) (46)
- Autonomic nervous system and secretion across the intestinal mucosal surface (2007) (46)
- Mucosal responses evoked by stimulation of ganglion cell somas in the submucosal plexus of the guinea‐pig ileum. (1985) (45)
- Neural 5-hydroxytryptamine receptors regulate chloride secretion in guinea pig distal colon. (1991) (45)
- Vasoactive intestinal polypeptide: a transmitter in submucous neurons mediating secretion in guinea pig distal colon. (1994) (44)
- Dual purinergic synaptic transmission in the human enteric nervous system. (2008) (43)
- Cholinergic receptors mediating secretion in guinea pig colon. (1987) (42)
- Neuropeptide modification of chloride secretion in guinea pig distal colon (1987) (42)
- H2 receptors mediate cyclical chloride secretion in guinea pig distal colon. (1990) (40)
- Coordination of Cl- secretion and contraction by a histamine H2-receptor agonist in guinea pig distal colon. (1993) (35)
- Effects of neurotransmitter release on mucosal transport in guinea pig ileum. (1983) (34)
- Elevation of cAMP facilitates noradrenergic transmission in submucous neurons of guinea pig ileum. (1993) (31)
- Neuroimmune interactions: role for cholinergic neurons in intestinal anaphylaxis. (1992) (31)
- Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon. (2009) (29)
- Acetylcholine release from colonic submucous neurons associated with chloride secretion in the guinea pig. (1992) (29)
- Activation of neuronal adenosine A1 receptors suppresses secretory reflexes in the guinea pig colon. (1999) (29)
- Purinergic Autocrine Regulation of Mechanosensitivity and Serotonin Release in a Human EC Model: ATP-gated P2X3 Channels in EC are Downregulated in Ulcerative Colitis (2013) (29)
- CHAPTER 27 – Enteric Neural Regulation of Mucosal Secretion (2006) (28)
- Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation. (2007) (28)
- Effects of tetrodotoxin on chloride secretion in rabbit distal colon: tissue and cellular studies. (1990) (28)
- Muscarinic receptor subtypes mediating the mucosal response to neural stimulation of guinea pig ileum. (1987) (26)
- Neurokinin 1 receptors mediate substance P-induced changes in ion transport in guinea-pig ileum (1992) (25)
- Transmural fluxes of 5-hydroxytryptamine in guinea pig ileum. (1983) (25)
- Vasoactive intestinal polypeptide actions on the guinea pig intestinal mucosa during neural stimulation. (1987) (25)
- Effect of hibernation and jejunal bypass on mucosal structure and function. (1991) (24)
- PACAP Induces Signaling and Stimulation of 5-Hydroxytryptamine Release and Growth in Neuroendocrine Tumor Cells (2009) (23)
- The Origin of the Makgadikgadi Pans (1979) (23)
- Transport characteristics of isolated newborn rabbit ileum. (1978) (23)
- Human α-calcitonin gene-related peptide influences colonic secretion by acting on myenteric neurons (1989) (22)
- Synaptic transmission in submucosal ganglia of guinea pig distal colon. (1991) (20)
- Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine. (2009) (20)
- The effects of cisapride on serotonin-evoked mucosal responses in guinea-pig ileum. (1984) (19)
- Loss of absorptive capacity for sodium and chloride in the colon causes diarrhoea in Potomac horse fever. (1992) (18)
- Electrophysiological properties of neurons in submucosal ganglia of guinea pig distal colon. (1991) (17)
- Cholinergic and VIP-ergic pathways mediate histamine H2 receptor-induced cyclical secretion in the guinea pig colon. (1995) (17)
- Mechanically evoked 5‐hydroxytryptamine release is mediated by caveolin‐associated cholesterol rich membrane domains (2007) (16)
- Tonic activity of submucosal neurons influences basal ion transport. (1989) (15)
- Neuro‐Modulation of Ion Secretion by Inflammatory Mediators a (1992) (14)
- Effects of enteric neural stimulation on chloride transport in human left colonin vitro (1989) (14)
- Submucosal nerves and cholera toxin-induced secretion in guinea pig ileumin vitro (1986) (13)
- Calcitonin Gene—Related Peptides: Influence on Intestinal Ion Transport a (1992) (12)
- Neuromodulation of intestinal transport in the suckling mouse. (1989) (12)
- A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon (2003) (12)
- Complexities of nervous control of the intestinal epithelium. (1988) (11)
- Thyrotropin-releasing hormone excites submucous neurons in guinea-pig ileum. (1991) (11)
- H3 receptors: modulation of histamine-stimulated neural pathways influencing electrogenic ion transport in the guinea pig colon. (1994) (10)
- Enteric Neural Reflexes and Secretion (2003) (9)
- Amino acid transport in the developing chicken kidney. (1973) (7)
- Endogenous nitric oxide inhibits endothelin-1-induced chloride secretion in guinea pig colon. (1998) (7)
- The problem of drought in Botswana (1978) (6)
- Intestinal secretion after jejunal bypass in the ground squirrel. (1992) (6)
- Correlation between the weight of gastric mucosa and maximal acid secretion. (1968) (6)
- Tryptophan transport by isolated newborn rabbit jejunum. (1980) (6)
- THE PUBLIC DEBT LIMIT (1954) (6)
- Activation of neuronal adenosine A1 receptors suppresses secretory reflexes in the guinea pig colon. (1999) (5)
- Jejunal transport properties of piebald mouse model for Hirschsprung's disease. (1980) (4)
- Nerve-mediated action of forskolin on guinea pig ileal mucosa (1985) (4)
- Effect of tryptophan on transport properties of newborn rabbit jejunum. (1982) (4)
- Effect of aspirin on sugar, amino acid, and sodium transport in rat jejunum. (1979) (3)
- Gastric emptying and small intestinal transit in the piebald mouse model for Hirschsprung's disease (1984) (3)
- Clearance and Microperfusion Study of EDTA-51 Cr Excretion by Rat Kidney (1968) (3)
- Development of glomerular filtration rate and electrolyte and osmolal clearance in the late-embryonic and newly hatched chicken (2004) (3)
- Adenosine acts at A1, A2A and A2B receptors to modulate 5-hydroxytryptamine release from human bon cells (2000) (2)
- Antisense oligonucleotide suppression of expression of VIP receptors in diverse intestinal cells (1998) (2)
- Effects of neuropeptide Y on submucous neurons in the guinea-pig small intestine (1992) (2)
- Thyrotropin-releasing hormone (TRH) evokes chloride secretion via cholinergic pathways in the guinea-pig ileum. (1989) (2)
- Gastric emptying and small intestinal transit in the piebald mouse model for Hirschsprung's disease. (1984) (2)
- Actions of 5-hydroxytryptamine on electrical and synaptic behavior of submucosal neurons in guinea pig colon. (1990) (1)
- Enhanced tissue responsiveness in colonic ion transport of cow's milk-sensitized guinea pigs (1994) (1)
- Corrigendum to “A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon” [Regul. Pept. 114 (2003) 51–60] (2003) (1)
- Adenosine A1 receptor agonist augments mechanically-evoked release of 5-Hydroxytryptamine from human bon cells (2000) (1)
- Influence of calcitonin gene-related peptide (CGRP) on intestinal transport (1991) (1)
- Amplification and immune modulation in the Ac/cAMP signaling pathway leads to hyperexcitability in intrinsic primary afferent (AH) neurons of Trichinella spiralis infected-guinea pigs* (2003) (1)
- Neural adenosine A3 receptors are negatively coupled to neuromuscular transmission in rat colon (2000) (1)
- Neuromodulation of ion secretion (1992) (0)
- The role of speleology in environmental studies (1992) (0)
- Vasoactive Intestinal Polypeptide AC on the Guinea Pig Intestinal Mucosa During Neural Stimulation tions (1987) (0)
- Coordination of secretion and contractility in the guinea pig colon: Role for histamine (1992) (0)
- Mechanosensory Transduction ' ' The Force Be with You ' ' : ATP in Gut (2003) (0)
- Modulating CL secretion by changing expression of vasoactive intestinal polypeptide-1 receptor (VIP, R) in guinea pig distal colon in vitro (2001) (0)
- Adenosine A3 receptor expression in peplidergic neural circuits of the rat distal colon (2001) (0)
- T1380 Lubiprostone Enhances Histamine H2 Receptor-Mediated Cyclical Chloride Secretion in the Guinea Pig Colon (2008) (0)
- Intestinal transport in megacolonic mice (1989) (0)
- Scientific illiteracy: impact on research and what can be done. (1993) (0)
- Cloning and expression of the guinea pig vasoactive intestinal polypeptide receptor-1 (2000) (0)
- Nucleotide activation of P2Y receptors on submucosal neurons regulates chloride secretion via prostaglandin-dependent and independent mechanisms (2003) (0)
- Caveolin-1 suppresses mechanically evoked activation of Gαq-coupled 5-HT release from BON cells (2001) (0)
- Mechanical stimulation of human BON cells: Gαq involvement in 5-HT release (2001) (0)
- Nerves and secretory mechanisms (1999) (0)
- Role for somatostatin receptors in discriminating between mechanosensitive release of 5-HT and PGE2 in the initiation of secretory reflexes in the guinea pig colon* (1998) (0)
- Role for purinergic A1 receptors in submucosal secretory reflexes in the guinea PIG colon (1998) (0)
- Effect of streptozocin‐induced hyperglycemia on 5‐hydroxytryptamine (5‐HT) evoked coordinated motility/secretory responses in colon (2006) (0)
- Ulcerative Colitis Alters Gut Expression of Purinergic Ionotropic P2X3 and Metabotropic a2B or a3 Receptors – Is P2X a Fast Mechanosensor in EC Cells? (2011) (0)
- The role of debt in the economy (1962) (0)
- Tryptophan and Intestinal Secretion (1984) (0)
- Gastrointestinal Motility Tracking the Moveable Feast: Sonomicrometry and (2015) (0)
- Over-expressed human BON cell P2Y11Rs in HEK-293 cells are coupled predominantly to a cAMP-dependent signaling pathway (2003) (0)
- Mechanical stimulation of human carcinoid BON cells leads to 5-HT release via a phospholipase C/Ca2+ signaling pathway (2003) (0)
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