Helen Walden | Academic Influence

Helen Walden's AcademicInfluence.com Rankings

Helen Walden

Chemistry

#5769

World Rank

#6995

Historical Rank

chemistry Degrees

Helen Walden

Biology

#9669

World Rank

#12899

Historical Rank

Molecular Biology

#2380

World Rank

#2417

Historical Rank

Biochemistry

#2569

World Rank

#2738

Historical Rank

biology Degrees

Download Badge

Chemistry
Biology

Helen Walden's Degrees

Masters Biochemistry University of Oxford
Bachelors Chemistry University of Oxford

Why Is Helen Walden Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Helen Walden is an English structural biologist who received the Colworth medal from the Biochemical Society in 2015. She was awarded European Molecular Biology Organization membership in 2022. She is a Professor of Structural Biology at the University of Glasgow and has made significant contributions to the Ubiquitination field.

(See a Problem?)

Helen Walden's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 (2012) (744)
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. (2009) (384)
Autoregulation of Parkin activity through its ubiquitin‐like domain (2011) (310)
Ubiquitin signalling in DNA replication and repair (2010) (274)
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. (2003) (247)
Types of Ubiquitin Ligases (2016) (238)
The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder. (2014) (212)
RBR E3 ubiquitin ligases: new structures, new insights, new questions (2014) (211)
Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8 (2003) (208)
Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability. (2011) (192)
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation (2015) (168)
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations (2005) (161)
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis (2015) (152)
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease (2013) (131)
Tiny TIM: a small, tetrameric, hyperthermostable triosephosphate isomerase. (2001) (129)
Ubiquitin-like protein activation (2004) (89)
RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns (2018) (82)
Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection (2014) (78)
Selenium incorporation using recombinant techniques (2010) (77)
The Structural Basis for Substrate Promiscuity in 2-Keto-3-deoxygluconate Aldolase from the Entner-Doudoroff Pathway in Sulfolobus solfataricus* (2004) (75)
Regulation of Parkin E3 ubiquitin ligase activity (2012) (74)
Parkin-phosphoubiquitin complex reveals a cryptic ubiquitin binding site required for RBR ligase activity (2017) (69)
Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway* (2011) (58)
Structural analysis of Escherichia coli ThiF. (2005) (54)
Parkin function in Parkinson's disease (2018) (52)
Ubiquitin and Parkinson's disease through the looking glass of genetics (2017) (51)
Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 (2016) (46)
Specificity and disease in the ubiquitin system (2016) (46)
The structure of FANCL, the catalytic subunit of the Fanconi Anemia core complex (2010) (40)
Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation (2012) (36)
Structure and function of a regulated archaeal triosephosphate isomerase adapted to high temperature. (2004) (32)
Structural basis of generic versus specific E2–RING E3 interactions in protein ubiquitination (2019) (31)
University of Dundee Structure of the Human FANCL RING-Ube 2 T Complex Reveals Determinants of Cognate E 3E 2 Selection (2017) (30)
Towards a Molecular Understanding of the Fanconi Anemia Core Complex (2012) (30)
Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening (2017) (26)
RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation (2018) (25)
Characterization of FANCL variants observed in patient cancer cells (2020) (25)
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation (2018) (24)
Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA (2020) (24)
Allosteric mechanism for site-specific ubiquitination of FANCD2 (2019) (22)
The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL* (2015) (20)
Modes of allosteric regulation of the ubiquitination machinery. (2020) (19)
Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements (2017) (16)
Mechanism, specificity, and function of FANCD2‐FANCI ubiquitination and deubiquitination (2021) (14)
Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1 (2018) (13)
Structural basis of FANCD2 deubiquitination by USP1−UAF1 (2020) (13)
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits (2020) (12)
Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins. (2019) (10)
Triosephosphate isomerase of the hyperthermophile Thermoproteus tenax: thermostability is not everything. (2004) (9)
A mechanistic review of Parkin activation. (2021) (9)
Insights into the ubiquitin transfer cascade from the structure of the E1 for NEDD8. (2003) (8)
Mechanism and disease association of E 2-conjugating enzymes : lessons from UBE 2 T and UBE 2 L 3 (2016) (3)
University of Dundee Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK 1-dependent phosphorylation and activation (2015) (2)
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site (2022) (2)
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex (2003) (2)
Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin (2022) (2)
Allosteric network in Ube2T drives specificity for RING E3 catalysed ubiquitin signals (2018) (2)
Molecular replacements (2013) (1)
Crystal structure of truncated USP1-UAF1 reacted with ubiquitin-prg (2021) (0)
Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination (2022) (0)
UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin (2018) (0)
WT-Parkin and pUB complex (2017) (0)
Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase (2005) (0)
Crystal structure of tetrameric TIM from Pyrococcus woesei. (2001) (0)
Structural insights into ubiquitin-like protein transfer cascades (2005) (0)
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP (2003) (0)
Crystal structure of human Ube2T E54R mutant (2019) (0)
Triosephosphate isomerase from Thermoproteus tenax (2004) (0)
Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and FANCI (2021) (0)
Human FANCL central domain (2011) (0)
Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with pyruvate (2004) (0)
Crystal structure of truncated USP1-UAF1 (2021) (0)
University of Dundee RNF 12 X-linked intellectual disability mutations disrupt E 3 ligase activity and neural differentiation (0)
Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase (2005) (0)
2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus (2004) (0)
Regulation of Parkin E3 ubiquitin ligase activity (2012) (0)
RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns (2018) (0)
Ube2T in complex with fragment EM04 (2017) (0)
phosphorylating Serine 65 depolarization and stimulates Parkin E3 ligase activity by PINK1 is activated by mitochondrial membrane potential (2013) (0)
Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with D-KDGal, D-Glyceraldehyde and pyruvate (2004) (0)
Distinct phosphorylation signals drive acceptor versus self-ubiquitination selection by Parkin (2021) (0)
Structure of an E2-E3 complex (2014) (0)
S65DParkin and pUB complex (2017) (0)
Crystal structure of the Zn-bound ubiquitin-conjugating enzyme Ube2T (2017) (0)
Crystal Structure of FANCL (2010) (0)
Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination (2022) (0)

This paper list is powered by the following services:

Other Resources About Helen Walden

en.wikipedia.org

What Schools Are Affiliated With Helen Walden?

Helen Walden is affiliated with the following schools:

Image Attributions

Image Source for Helen Walden