Helle Krogh Johansen

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#16339

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Ecology

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#849

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Biology

Helle Krogh Johansen's Degrees

PhD Biology University of Copenhagen
Masters Biology University of Copenhagen

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Helle Krogh Johansen's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The clinical impact of bacterial biofilms (2011) (651)
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective (2012) (622)
Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis (2014) (451)
Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB‐oprM genes (2008) (431)
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth. (2001) (371)
Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. (2010) (350)
Evolutionary dynamics of bacteria in a human host environment (2011) (339)
Rupture in small abdominal aortic aneurysms. (1998) (255)
Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr−/− Mice (2007) (255)
Ghost Authorship in Industry-Initiated Randomised Trials (2007) (254)
Environmental Study of Azole-Resistant Aspergillus fumigatus and Other Aspergilli in Austria, Denmark, and Spain (2010) (232)
National Surveillance of Fungemia in Denmark (2004 to 2009) (2010) (220)
Molecular Epidemiology and Dynamics of Pseudomonas aeruginosa Populations in Lungs of Cystic Fibrosis Patients (2007) (213)
In Situ Growth Rates and Biofilm Development of Pseudomonas aeruginosa Populations in Chronic Lung Infections (2007) (211)
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection (2011) (200)
Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators (2013) (199)
Seasonal onset of initial colonisation and chronic infection with Pseudomonas aeruginosa in patients with cystic fibrosis in Denmark. (1992) (199)
Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme. (2013) (192)
PhoQ Mutations Promote Lipid A Modification and Polymyxin Resistance of Pseudomonas aeruginosa Found in Colistin-Treated Cystic Fibrosis Patients (2011) (185)
Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia (2011) (175)
Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis (2005) (171)
PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients (2011) (170)
House dust mite control measures for asthma: systematic review (2008) (167)
Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients. (2008) (166)
Aspergillus Species and Other Molds in Respiratory Samples from Patients with Cystic Fibrosis: a Laboratory-Based Study with Focus on Aspergillus fumigatus Azole Resistance (2011) (164)
National Surveillance of Fungemia in Denmark 2010-11 (2012) (162)
Severity of cystic fibrosis in patients homozygous and heterozygous for ΔF508 mutation (1991) (152)
Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa (2014) (150)
Comparing Whole-Genome Sequencing with Sanger Sequencing for spa Typing of Methicillin-Resistant Staphylococcus aureus (2014) (145)
Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography. (2011) (142)
Long-term social dynamics drive loss of function in pathogenic bacteria (2015) (141)
Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility. (2008) (133)
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis (2020) (128)
Antibiofilm Properties of Acetic Acid. (2014) (126)
Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice (1997) (125)
Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts. (2010) (124)
Problems in the design and reporting of trials of antifungal agents encountered during meta-analysis. (1999) (122)
House dust mite control measures for asthma. (2001) (116)
Coexistence and Within-Host Evolution of Diversified Lineages of Hypermutable Pseudomonas aeruginosa in Long-term Cystic Fibrosis Infections (2014) (105)
Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections (2018) (105)
House dust mite control measures for asthma. (2008) (104)
Meta-analysis of short term low dose prednisolone versus placebo and non-steroidal anti-inflammatory drugs in rheumatoid arthritis (1998) (103)
Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response. (2012) (101)
Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia (1997) (101)
Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone (2017) (96)
Polymyxin Resistance of Pseudomonas aeruginosa phoQ Mutants Is Dependent on Additional Two-Component Regulatory Systems (2013) (91)
Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: A marker of therapeutic success?—A 30‐year Cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection (2004) (85)
Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis (2019) (85)
Constraints on publication rights in industry-initiated clinical trials. (2006) (85)
Update from a 12-Year Nationwide Fungemia Surveillance: Increasing Intrinsic and Acquired Resistance Causes Concern (2017) (84)
Interferon‐gamma (IFN‐γ) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats (1996) (83)
A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility (2011) (82)
Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients (2003) (82)
Long-term survival and nutritional data in patients with cystic fibrosis treated in a Danish centre. (1996) (80)
Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media (2009) (78)
A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. (2015) (77)
Emergence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Bloodstream Infections in Denmark (2017) (76)
Ginseng treatment reduces bacterial load and lung pathology in chronic Pseudomonas aeruginosa pneumonia in rats (1997) (75)
Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease. (2016) (72)
Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. (2000) (72)
Pre‐adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates (2016) (71)
Evolutionary highways to persistent bacterial infection (2019) (71)
Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction (2015) (71)
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs (2018) (70)
Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis (2014) (68)
Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation. (2010) (67)
Antagonism between penicillin and erythromycin against Streptococcus pneumoniae in vitro and in vivo. (2000) (66)
P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs. (2013) (64)
Effects of Ginseng Treatment on Neutrophil Chemiluminescence and Immunoglobulin G Subclasses in a Rat Model of Chronic Pseudomonas aeruginosa Pneumonia (1998) (63)
The Effect of Sinus Surgery with Intensive follow-up on Pathogenic Sinus Bacteria in Patients with Cystic Fibrosis (2013) (63)
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients (2015) (59)
Pseudomonas aeruginosa and Burkholderia cepacia infection in cystic fibrosis patients treated in Toronto and Copenhagen (1998) (57)
In vivo emergence of Aspergillus terreus with reduced azole susceptibility and a Cyp51a M217I alteration. (2012) (57)
Defining antimicrobial resistance in cystic fibrosis. (2018) (56)
Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed? (2013) (56)
Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization. (2013) (56)
Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats (1993) (55)
Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. (2005) (54)
Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study (2015) (53)
Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry (2016) (53)
Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections. (2019) (52)
House dust mite control measures for asthma. (2001) (52)
Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa (2018) (52)
Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts (2018) (51)
Stepwise Development of a Homozygous S80P Substitution in Fks1p, Conferring Echinocandin Resistance in Candida tropicalis (2012) (51)
Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection (1994) (51)
Increased incidence of Mycoplasma pneumoniae infections detected by laboratory-based surveillance in Denmark in 2010. (2010) (51)
Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis. (2011) (51)
Cross-reactive antigens shared by Pseudomonas aeruginosa, Helicobacter pylori, Campylobacter jejuni, and Haemophilus influenzae may cause false-positive titers of antibody to H. pylori (1995) (50)
Severity of cystic fibrosis in patients homozygous and heterozygous for delta F508 mutation. (1991) (49)
Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients. (2015) (49)
Early treatment with inhaled antibiotics postpones next occurrence of Achromobacter in cystic fibrosis. (2013) (48)
Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats. (1995) (48)
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis. (2008) (48)
Voriconazole versus amphotericin B in cancer patients with neutropenia. (2006) (48)
Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice (2009) (48)
Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis. (2011) (48)
Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients. (2009) (47)
Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection. (2010) (47)
Ginseng treatment enhances bacterial clearance and decreases lung pathology in athymic rats with chronic P. aeruginosa pneumonia (1997) (47)
Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing. (2015) (46)
Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections. (2016) (44)
Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia (2017) (44)
Clinical care of children with primary ciliary dyskinesia (2017) (42)
Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates. (2012) (42)
Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment (2019) (42)
CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients. (2012) (42)
Nystatin prophylaxis and treatment in severely immunodepressed patients. (2014) (41)
Sinus surgery postpones chronic Gram-negative lung infection: cohort study of 106 patients with cystic fibrosis. (2017) (41)
Evaluation of Caspofungin Susceptibility Testing by the New Vitek 2 AST-YS06 Yeast Card Using a Unique Collection of FKS Wild-Type and Hot Spot Mutant Isolates, Including the Five Most Common Candida Species (2012) (40)
Pseudomonas aeruginosa Adaptation to Lungs of Cystic Fibrosis Patients Leads to Lowered Resistance to Phage and Protist Enemies (2013) (38)
Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia (2015) (38)
Excretion of β-Lactam Antibiotics in Sweat—a Neglected Mechanism for Development of Antibiotic Resistance? (2000) (38)
Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa (2018) (38)
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19 (2021) (37)
Bacteriocin-mediated competition in cystic fibrosis lung infections (2015) (37)
Mutations in 23S rRNA Confer Resistance against Azithromycin in Pseudomonas aeruginosa (2012) (36)
Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients (2015) (35)
Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients (2019) (34)
Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics. (1996) (33)
Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia. (2014) (33)
Towards quantitative SERS detection of hydrogen cyanide at ppb level for human breath analysis (2015) (32)
Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients (2019) (31)
Emergence of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of two CTX-M-15 clones with multilocus sequence types 15 and 16 in Zealand. (2011) (31)
Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia. (2000) (31)
Achromobacter species in cystic fibrosis: cross-infection caused by indirect patient-to-patient contact. (2013) (31)
Nystatin prophylaxis and treatment in severely immunodepressed patients. (2002) (30)
Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa. (2006) (30)
The Immune Response to Bacterial Biofilms (1995) (30)
Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus. (2001) (28)
Differentiation of Candida glabrata, C. nivariensis and C. bracarensis based on fragment length polymorphism of ITS1 and ITS2 and restriction fragment length polymorphism of ITS and D1/D2 regions in rDNA (2011) (28)
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study. (2015) (27)
Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection. (2015) (27)
Frequency of the delta F508 mutation on cystic fibrosis chromosomes in Denmark. (1990) (26)
Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis (2017) (26)
Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate (2019) (25)
Potential of preventing Pseudomonas aeruginosa lung infections in cystic fibrosis patients: Experimental studies in animals (1996) (25)
Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis. (2001) (25)
Routine versus selective antifungal administration for control of fungal infections in patients with cancer. (2000) (25)
Bacterial evolution in PCD and CF patients follows the same mutational steps (2016) (24)
Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs (2017) (24)
Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link? (2017) (24)
Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis (2020) (24)
Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. (2002) (24)
Privatisation rescues function following loss of cooperation (2018) (24)
Linezolid as rescue treatment for left-sided infective endocarditis: an observational, retrospective, multicenter study (2012) (23)
A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF. (2013) (23)
SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients (2017) (22)
Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease. (2010) (21)
Is parotid saliva sterile on entry to the oral cavity? (2017) (21)
A novel knee prosthesis model of implant-related osteo- myelitis in rats (2013) (21)
The Small RNA ErsA of Pseudomonas aeruginosa Contributes to Biofilm Development and Motility through Post-transcriptional Modulation of AmrZ (2018) (21)
Experimental immunization with Pseudomonas aeruginosa alginate induces IgA and IgG antibody responses (1991) (21)
Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients. (2014) (20)
Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats. (2017) (20)
Increasing prevalence of group B streptococcal infection among pregnant women. (2014) (20)
Unusual Distribution of Burkholderia cepacia Complex Species in Danish Cystic Fibrosis Clinics May Stem from Restricted Transmission between Patients (2010) (20)
Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis (2021) (19)
Vaccines for preventing infection with Pseudomonas aeruginosa in people with cystic fibrosis. (1999) (19)
High incidence of candidaemia in a nationwide cohort: Underlying diseases, risk factors and mortality. (2018) (19)
Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia. (2014) (18)
Inter-species interactions alter antibiotic efficacy in bacterial communities (2021) (18)
Routine versus selective antifungal administration for control of fungal infections in patients with cancer. (2014) (18)
Pseudomonas aeruginosa diversity in distinct paediatric patient groups. (2008) (18)
Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia (2018) (17)
Intravenous alpha-1 antitrypsin augmentation therapy: systematic review. (2010) (17)
Hypermutation as an Evolutionary Mechanism for Achromobacter xylosoxidans in Cystic Fibrosis Lung Infection (2020) (17)
Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations (2006) (17)
Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle. (1997) (17)
Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms (2020) (16)
Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples. (2020) (16)
Ciprofloxacin in sweat and antibiotic resistance (1995) (16)
Effects of Radix Angelicae sinensis and shuanghuanglian on a rat model of chronic Pseudomonas aeruginosa pneumonia. (2000) (15)
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis. (2015) (15)
Local IgA and IgG response to intratracheal immunization with Pseudomonas aeruginosa antigens (1992) (15)
Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways (2020) (15)
An exploratory study of microbial diversity in sinus infections of cystic fibrosis patients by molecular methods. (2014) (15)
Relative Increase in IgG Antibodies to Pseudomonas aeruginosa 60-kDa GroEL in Prediabetic Patients with Cystic Fibrosis (2001) (14)
Mannan‐binding lectin is a determinant of survival in infective endocarditis (2007) (14)
Extensive Endoscopic Image‐Guided Sinus Surgery Decreases BPI‐ANCA in Patients with Cystic Fibrosis (2012) (14)
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis.. (2013) (14)
Frequency of the ΔF508 mutation on cystic fibrosis chromosomes in Denmark (1990) (14)
Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments (2020) (13)
Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H (2020) (13)
[Constraints on publication rights in industry-initiated clinical trials--secondary publication]. (2006) (13)
Characterization of carbapenem nonsusceptible Pseudomonas aeruginosa in Denmark: a nationwide, prospective study. (2014) (13)
The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy. (2018) (13)
Effects of Chinese medicinal herbs on a rat model of chronic Pseudomonas aeruginosa lung infection (1996) (12)
Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways? (2016) (12)
Omics-based tracking of Pseudomonas aeruginosa persistence in “eradicated” cystic fibrosis patients (2020) (12)
Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective (2021) (11)
Rat Model of Chronic Pseudomonas aeruginosa Lung Infection (1999) (11)
Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. (2014) (11)
Clearance of Pseudomonas aeruginosa from normal rat lungs after immunization with somatic antigens or toxin A (1994) (11)
Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. (2001) (9)
Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis. (1996) (9)
Misleading statements in industry-sponsored meta-analysis of itraconazole. (2005) (9)
Bacterial Re-Colonization Occurs Early after Lung Transplantation in Cystic Fibrosis Patients (2021) (9)
[Biofilm, foreign bodies and chronic infections]. (1994) (9)
High persister phenotype of Pseudomonas Aeruginosa is associated with increased fitness in cystic fibrosis airways (2018) (9)
Low incidence of pulmonary Pseudomonas cepacia infection in Danish cystic fibrosis patients (1992) (9)
Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed? (2015) (9)
Ciprofloxacin in sweat and antibiotic resistance. The Copenhagen Study Group on Antibiotics in Sweat. (1995) (8)
House dust mite control measures for asthma. (2004) (8)
Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients (2011) (8)
Routine versus selective antifungal administration for control of fungal infections in patients with cancer. (2000) (8)
Nystatin prophylaxis and treatment in severely immunodepressed patients. (2000) (8)
Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review? (2007) (8)
Adaptive Interactions of Achromobacter spp. with Pseudomonas aeruginosa in Cystic Fibrosis Chronic Lung Co-Infection (2021) (7)
Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients. (2002) (7)
Effect of Long-Term Voluntary Exercise Wheel Running on Susceptibility to Bacterial Pulmonary Infections in a Mouse Model (2013) (7)
House dust mite control measures for asthma. (2008) (7)
Oropharyngeal Candidiasis in Palliative Care Patients in Denmark. (2015) (7)
Experimental chronic Pseudomonas aeruginosa lung infection in rats (1995) (7)
Gene loss and acquisition in lineages of bacteria evolving in a human host environment (2020) (7)
Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment (2018) (7)
Developmental stability in a cystic fibrosis mouse model (2004) (7)
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs (2018) (7)
The high persister phenotype ofPseudomonas aeruginosais associated with increased fitness and persistence in cystic fibrosis airways (2019) (7)
International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives (2021) (6)
[Ginseng modulates the immune response via its effect on cytokine production--secondary publication]. (2005) (6)
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double‐blind, placebo‐controlled Phase 2 trial (2022) (6)
Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis. (2004) (6)
Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy (2013) (6)
Response to multimodal treatment in advanced neuroblastomas. Factors associated with complete remission induction, and factors associated with prolonged survival. (1989) (6)
Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients (2017) (6)
Clinical Relevance of Pseudomonas aeruginosa: A Master of Adaptation and Survival Strategies (2008) (5)
[Foreign body infections--biofilms and quorum sensing]. (2007) (5)
Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution (2022) (5)
Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs (2020) (4)
Achromobacter spp. genetic adaptation in cystic fibrosis (2021) (4)
High‐throughput dilution‐based growth method enables time‐resolved exo‐metabolomics of Pseudomonas putida and Pseudomonas aeruginosa (2021) (4)
Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease. (2022) (4)
Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study (2018) (4)
Changes in T1 relaxation processes in the bone marrow following treatment in children with acute lymphoblastic leukemia (1990) (4)
Bio¢lms in chronic infections ^ a matter of opportunity ^ monospecies bio¢lms in multispecies infections (2010) (4)
Routine versus selective antifungal administration for control of fungal infections in patients with cancer. (2002) (3)
Fungal infection-related mortality versus total mortality as an outcome in trials of antifungal agents (2006) (3)
SERS spectroscopy for detection of hydrogen cyanide in breath from children colonised with P. aeruginosa (2017) (3)
Are encasings effective in asthma caused by house dust mite allergens? (2003) (3)
Core and accessory effectors of type VI secretion systems contribute differently to the intraspecific diversity of Pseudomonas aeruginosa (2022) (3)
Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance (2022) (3)
PmrB mutations promote polymyxin resistance of Pseudomonas (2011) (3)
Amphotericin B vs fluconazole for controlling fungal infections in neutropenic cancer patients. (2000) (3)
A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia (2021) (3)
Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs (2022) (3)
Author’s reply on: ‘House dust mite control measures for asthma’ (2009) (2)
The relation of biofilms to chronic otitis media and other ear related chronic infections (2011) (2)
[Effects of subcutaneous injection with different doses of ginseng on the rat model of chronic Pseudomonas aeruginosa pneumonia]. (1998) (2)
Achromobacter genetic adaptation in cystic fibrosis (2021) (2)
WS24.2 Extensive sinus surgery and follow-up can eradicate pathogenic bacterial sinusitis in patients with cystic fibrosis (CF) (2012) (2)
Use of inhaled antibiotics among Danish patients with cystic fibrosis (2022) (2)
Achromobacter spp. in a Cohort of Non-Selected Pre- and Post-Lung Transplant Recipients (2022) (2)
Evolutionary dynamics of pseudomonas aeruginosa in CF (2012) (2)
Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study (2022) (2)
[Epiglottitis with an abscess caused by Haemophilus parainfluenzae]. (2014) (2)
Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone (2017) (2)
Anatomy of the Cochrane Review (2001) (2)
What Makes Pseudomonas Aeruginosa Persist in the Lungs of CF Patients (2015) (2)
Aspergillus species and other moulds in respiratory samples from cystic fibrosis patients: A laboratory-based study with focus on azole-resistance in Aspergillus fumigatus (2019) (2)
Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis (2005) (2)
Evolutionary highways to persistent bacterial infection (2018) (2)
Erratum to “Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization” [J Cyst Fibros 12 (1) (2013) 81–7] (2013) (2)
Genetic adaptation and transmission of Achromobacter in cystic fibrosis (2020) (1)
WS16.3 Rethinking Pseudomonas aeruginosa (PA) lung infection: using molecular microbiology rather than culture and antibodies (2014) (1)
Author’s reply on: ‘House dust mite control measures for asthma’ (2009) (1)
353 Achromobacter xylosoxidans in cystic fibrosis: indirect patient-to-patient contact can lead to cross-infection (2012) (1)
[Microbial biofilm in rhinosinusitis and cystic fibrosis]. (2011) (1)
National Surveillance of Fungaemia in Denmark 2004-2009 (2010) (1)
Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with COPD (2020) (1)
In Situ Growth Rates and Bioﬁlm Development of Pseudomonas aeruginosa Populations in Chronic Lung Infections (cid:1) (2008) (1)
EPS3.06 Ceftolozane/tazobactam: a new drug with superior effect against resistant P. aeruginosa (2021) (1)
Centrifugal microfluidic platform for optical monitoring and treatment of biofilms (2018) (1)
Microdevices: Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms (Adv. Healthcare Mater. 10/2020) (2020) (1)
New concepts in antimicrobial resistance in cystic fibrosis respiratory infections. (2022) (1)
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients (2015) (1)
Pseudomonas aeruginosa 50s ribosome from a clinical isolate with a mutation in uL6 (2019) (1)
The paranasal sinuses are focus for colonisation and chronic biofilm lung infection in CF patients (2008) (1)
Evolutionary highways to persistent infection by Pseudomonas aeruginosa (2018) (1)
Intermittent low dose prednisolone is safe in rheumatoid arthritis (1998) (1)
'Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance' Author's reply. (2022) (1)
Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae. (1999) (1)
Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment. (2021) (1)
Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways? (2016) (1)
[Acute infections of the hand]. (2009) (1)
HEAVY VEHICLES AND TRAFFIC SAFETY. SEMINAR IN SOEDERTAELJE 20-21 SEPTEMBER 1989 (1989) (0)
SystemsTwo-Component Regulatory Mutants Is Dependent on aeruginosa phoQ Pseudomonas Polymyxin Resistance of (2013) (0)
Microbial diversity in the lung S 41 WS 21 . 1 The genetic basis of Pseudomonas aeruginosa pathoadaptation to the airways of cystic fibrosis patients (2014) (0)
Paper811-14 march 1998 (1998) (0)
Early genetic adaptation associated with chronic pseudomonas aeruginosa airways infection (2012) (0)
122 Characterization of Pseudomonas aeruginosa populations in sputum from CF lungs using FISH, various staining methods and confocal microscopy (2006) (0)
ePS6.05 Combat of resistance development with collateral sensitivity of Pseudomonas aeruginosa cystic fibrosis lung isolates (2019) (0)
Pseudomonas aeruginosa 50s ribosome from a clinical isolate (2019) (0)
ePS3.02 Deciphering the adaptive evolution of successful Pseudomonas aeruginosa lineages within persistent bacterial infections (2022) (0)
Early Detection Of Bacterial Infections By Electrochemistry (2015) (0)
Development of a Biorefinery concept for integrated production of Biomedicals, Biochemicals, Food, Feed and Fuels from selected plant materials (BIOREF). (2011) (0)
127 Collateral sensitivity cycling of antibiotics for cystic fibrosis airway infections (2016) (0)
132 Molecular epidemiology and dynamics of chronic Pseudomonas aeruginosa populations in Cystic Fibrosis lungs (2006) (0)
[Has the new technology made Gram's staining method redundant? The Danish Society of Clinical Microbiology]. (2008) (0)
Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre (2010) (0)
P145 Monitoring of pulmonary infections in the Danish cystic fibrosis cohort during CFTR modulator therapy implementation (2022) (0)
Achromobacter xylosoxidans in patients with primary ciliary dyskinesia (2019) (0)
Characterisation of carbapenem non-susceptible Pseudomonas aeruginosa isolates in Danish hospitals: a nationwide study (2012) (0)
Pseudomonas aeruginosa 70s ribosome from an aminoglycoside resistant clinical isolate (2019) (0)
Nystatin prophylaxis and treatment in severely immunodepressed patients. (2014) (0)
55 Investigation of the RetS–GacAS regulatory network in clinical Pseudomonas aeruginosa isolates reveals evolutionary adaptation (2014) (0)
The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence (2022) (0)
The evolution and adaptation of clinical Pseudomonas aeruginosa isolates from early cystic fibrosis infections (2016) (0)
Unusual species distribution of Burkholderia isolates from Danish cystic fibrosis patients (2008) (0)
[The 2nd white coat revolution?]. (2008) (0)
WS5.3 Wide pharmacokinetic variability of ciprofloxacin in patients with cystic fibrosis (CF) – a reason of treatment failure? (2012) (0)
[Diagnosis of infectious diseases. Pneumonia]. (2001) (0)
Characterization of antibiotic resistance in clinical isolates of Klebsiella pneumoniae in Denmark (2021) (0)
Author response: Privatisation rescues function following loss of cooperation (2018) (0)
68 The physiological state of Pseudomonas aeruginosa populations in lungs of Cystic Fibrosis (CF) patients (2006) (0)
P1262 Ongoing semi-national surveillance of fungaemia in Denmark: species distribution and antifungal susceptibility (2007) (0)
Respiratory syncytial virus (RSV) enhances Pseudomonas aeruginosa lung infection in mice (2008) (0)
106 Pharmacokinetic variability of clarithromycin is due to differences in CYP3A4 activity in patients with cystic fibrosis (CF) – a reason for treatment failure? (2011) (0)
Microcontainers for improved treatment of Pseudomonas aeruginosa biofilm infections (2019) (0)
Establishing bacterial cell cultures on a centrifugal platform for monitoring of antibiotic resistance and biofilm development (2018) (0)
151* Sino-pulmonary pairs of mucoid and non-mucoid Pseudomonas aeruginosa isolates from cystic fibrosis patients with chronic airways infection have similar gene expression profiles (2011) (0)
Pseudomonas aeruginosa 70s ribosome from a clinical isolate (2019) (0)
Emergence of ESBL-producing Klebsiella pneumoniae in Danish hospitals: this is in part explained by spread of one CTX-M-15 clone in Zealand (2010) (0)
156 Adaptive metabolic changes in Pseudomonas aeruginosa during cystic fibrosis lung infection (2011) (0)
Early Detection Of Chronic Bacterial Infections By Microsensors (2015) (0)
[Is new prescription of antibiotics after treatment with sulfonamide or pivmecillinam a validated method for assessment of treatment failure?]. (2002) (0)
WS21.1 The genetic basis of Pseudomonas aeruginosa pathoadaptation to the airways of cystic fibrosis patients (2014) (0)
Diagnosis of bacterial biofilms in chronic sinusitis and pneumonia (2010) (0)
A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis (2023) (0)
100 Microbial physiology and persistence of Pseudomonas aeruginosa airway infections (2017) (0)
Achromobacter genetic adaptation in cystic fibrosis Running title Achromobacter genetic adaptation Authors and affiliations (2021) (0)
A decade of nation-wide fungaemia surveillance in Denmark: Current status and major trends (2015) (0)
80 Persistence of Pseudomonas aeruginosa in early stages of airway infection (2016) (0)
53 Genome changes leading to persistence of Pseudomonas aeruginosa in the airways of CF patients (2014) (0)
Long-term evolution of antibiotic persistence in P. aeruginosa lung infections (2021) (0)
78 Pharmacokinetic variability of clarithromycin and ciprofloxacin in patients with cystic fibrosis (CF) (2013) (0)
76 Sinus surgery postpones chronic Gram-negative lung infection: cohort study of 106 patients with cystic fibrosis (2016) (0)
I3-YP-028Longitudinal study of Pseudomonas aeruginosa isolates from cystic fibrosis lungs (2008) (0)
P084 Counteracting inflammation triggered by Pseudomonas aeruginosa-ctivated lung-infiltrating Th1/17 cells: a novel approach for precision medicine in cystic fibrosis (2022) (0)
Immunization withPseudomonas aeruginosa Vaccines andAdjuvant CanModulate theTypeofInflammatory Response Subsequent toInfection (1994) (0)
Pseudomonas aeruginosa 30s ribosome from a clinical isolate (2019) (0)
92 Early treatment with inhaled antibiotics postpones recurrence of Achromobacter species in cystic fibrosis (2013) (0)
P138 Biochemical detection of Pseudomonas aeruginosa in sputum and urine from children with cystic fibrosis (2022) (0)
WS13.06 Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient (2022) (0)
Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient (2021) (0)
WS19.6 Diversity of Pseudomonas aeruginosa in cystic fibrosis airways (2015) (0)
Antibiotics as initial treatment for children with acute otitis media. Use of odds ratio in calculation of number needed to treat was inappropriate. (1997) (0)
116 Pharmacokinetic variability of ciprofloxacin in cystic fibrosis – is CYP3A4 involved? (2015) (0)
LIST OF PAPERS INCLUDED IN THIS THESIS I) Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia (2017) (0)
Investigation Of Contingent Mutations In The Rets-gacas Regulatory System In Clinical Pseudomonas Aeruginosa Isolates From Cystic Fibrosis Patients (2015) (0)
ePS5.01 Cystic fibrosis (CF) patients chronically infected with Pseudomonas aeruginosa have widespread alterations in both innate and adaptive immunity (2022) (0)
WS1.1 Evolutionary pathways in two dominant clinical Pseudomonas aeruginosa clones (2013) (0)
Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate (2019) (0)
Country-wide prevalence of ESBL-producing Enterobacteriaceae in 2009 (2011) (0)
P124 Collateral sensitivity in multidrug-resistant Pseudomonas aeruginosa (2022) (0)
Is The Ribosome Targeted By Adaptive Mutations (2015) (0)
EPS3.03 Using airway organoids and Air Liquid Interface cultures to profile the spatial and temporal dynamics of Pseudomonas aeruginosa infections (2021) (0)
112 Telithromycin inhibits the production of virulence factors and biofilm formation of P. aeruginosa without affecting its proliferation in vitro (2006) (0)
Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis (2010) (0)
ePS3.03 Using patient-derived airway models to study Pseudomonas aeruginosa colonisation and infection (2022) (0)
WS08.5 Omics-based surveillance of Pseudomonas aeruginosa infection identifies clonal persistence despite ‘eradication’ (2020) (0)
Treatment of Candidaemia in a nationwide setting: adherence to guidelines and effect (2017) (0)
Corrigendum to “CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients” [J Cyst Fibros 11(2012)93–99] (2013) (0)
A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis (2020) (0)
82 Increasing levels of precipitating antibodies to Achromobacter xylosoxidans and Burkholderia multivorans reflect more aggressive pulmonary disease in chronically infected Cystic Fibrosis patients (2006) (0)
Molecular Epidemiology and Dynamics of Pseudomonas aeruginosa Populations in Lungs of Cystic Fibrosis Patients (cid:1) (2007) (0)
University of Groningen Phamiacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis (2014) (0)
124 Saliva IgA antibodies is a diagnostic tool for sinusitis caused by Pseudomonas aeruginosa in patients with cystic fibrosis (2011) (0)
P132 Reduced systemic immune responses in cystic fibrosis patients (2021) (0)
Paranasal sinuses are a focus for P. aeruginosa (PA) lung infection in CF (2009) (0)
Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts (2018) (0)
Inflammatoriske og infektiøse tilstande i næse-bihuler (2012) (0)
Escherichia coli and Klebsiella pneumoniae ESBL genotype distribution in Denmark: CTX-M-15 prevails countrywide also in hospital epidemics (2011) (0)
Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa CF clinical isolates (2023) (0)
Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis in the Copenhagen CF Centre (2010) (0)
Linezolid in infective endocarditis - it seems to work (2010) (0)
Linezolid as rescue treatment for left-sided infective endocarditis: an observational, retrospective, multicenter study (2012) (0)
Dissecting the role of the small RNA ErsA in Pseudomonas aeruginosa motility and biofilm regulation (2017) (0)

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