Helmut Sies

Q: What Schools Are Affiliated With Helmut Sies

Helmut Sies is affiliated with the following schools: University of Oxford, Heinrich Heine University Düsseldorf, Hannover Medical School, University of Tübingen, King Saud University

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Helmut Sies

Biology

#845

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#1473

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Biochemistry

#52

World Rank

#68

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Helmut Sies

Philosophy

#1066

World Rank

#2010

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#130

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#307

Historical Rank

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Biology
Philosophy

Helmut Sies's Degrees

Doctorate Medicine University of Tübingen

Why Is Helmut Sies Influential?

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According to Wikipedia, Helmut Sies is a German physician, biochemist and university professor. He was the first to demonstrate the existence of hydrogen peroxide as a normal attribute of aerobic life in 1970, and he introduced the concept of Oxidative stress in 1985. He also worked on the biological strategies of antioxidant defense and the biochemistry of nutritional antioxidants .

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Helmut Sies's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Hydroperoxide metabolism in mammalian organs. (1979) (5212)
Oxidative stress: oxidants and antioxidants (1997) (4498)
Lycopene as the most efficient biological carotenoid singlet oxygen quencher. (1989) (2179)
Glutathione and its role in cellular functions. (1999) (1580)
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. (1981) (1528)
Strategies of antioxidant defense (1993) (1523)
Oxidative stress: a concept in redox biology and medicine (2015) (1492)
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents (2020) (1483)
Oxidative Stress. (2017) (1417)
Oxidative stress: from basic research to clinical application. (1991) (1249)
Chemistry of biologically important synthetic organoselenium compounds. (2001) (1206)
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress☆ (2017) (1155)
Antioxidant activity of carotenoids. (2003) (1105)
Vitamins E and C, beta-carotene, and other carotenoids as antioxidants. (1995) (1100)
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. (2006) (988)
Biochemistry of oxidative stress (1986) (883)
1 – Oxidative Stress: Introductory Remarks (1985) (830)
Bioactivity and protective effects of natural carotenoids. (2005) (785)
A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). (1984) (732)
Antioxidant Functions of Vitamins (1992) (731)
Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols. (1991) (714)
Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. (1992) (699)
Lycopene is more bioavailable from tomato paste than from fresh tomatoes. (1997) (694)
Lycopene: a biologically important carotenoid for humans? (1996) (687)
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. (1989) (644)
Sulfur and selenium: the role of oxidation state in protein structure and function. (2003) (632)
Strategies of antioxidant defense. (1993) (554)
Nutritional, dietary and postprandial oxidative stress. (2005) (548)
Vitamin E in humans: demand and delivery. (1996) (498)
Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations (1997) (478)
Protection against reactive oxygen species by selenoproteins. (2009) (467)
Oxidative stress: damage to intact cells and organs. (1985) (463)
The Redox Code (2015) (418)
Vascular effects of cocoa rich in flavan-3-ols. (2003) (415)
The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. (1988) (400)
The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established. (2011) (393)
Role of Metabolic H2O2 Generation (2014) (378)
Ebselen, a selenoorganic compound as glutathione peroxidase mimic. (1993) (371)
cis-trans isomers of lycopene and β-carotene in human serum and tissues (1992) (365)
Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. (1983) (350)
Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein (1998) (349)
Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers. (2005) (347)
Ultraviolet‐B Irradiation and Matrix Metalloproteinases (2002) (345)
Singlet Oxygen Mediates the UVA-induced Generation of the Photoaging-associated Mitochondrial Common Deletion* (1999) (336)
Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. (2008) (332)
Antioxidants in disease mechanisms and therapy (1997) (306)
Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress. (2003) (305)
Inhibition of 15-lipoxygenases by flavonoids: structure-activity relations and mode of action. (2003) (301)
Vitamins E and C are safe across a broad range of intakes. (2005) (299)
Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans. (2000) (297)
Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase. (1991) (295)
Protection against peroxynitrite (1999) (290)
Nutritional protection against skin damage from sunlight. (2004) (289)
Plasma antioxidants and longevity: a study on healthy centenarians. (2000) (288)
The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver. (1982) (288)
The biochemistry of selenium and the glutathione system. (2001) (284)
Total antioxidant capacity: appraisal of a concept. (2007) (283)
Evidence that Singlet Oxygen-induced Human T Helper Cell Apoptosis Is the Basic Mechanism of Ultraviolet-A Radiation Phototherapy (1997) (279)
Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen. (1991) (278)
Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers. (1990) (265)
Selenium, oxidative stress, and health aspects. (2005) (264)
Ebselen: prospective therapy for cerebral ischaemia (2000) (262)
Hydroperoxide-metabolizing systems in rat liver. (1975) (255)
The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors. (1973) (254)
Chemical depletion of glutathione in vivo. (1981) (248)
Quantitative assessment of antioxidant properties of natural colorants and phytochemicals: carotenoids, flavonoids, phenols and indigoids. The role of β‐carotene in antioxidant functions (2001) (246)
How do dietary flavanols improve vascular function? A position paper. (2008) (237)
Oxidation in the NADP system and release of GSSG from hemoglobin‐free perfused rat liver during peroxidatic oxidation of glutathione by hydroperoxides (1972) (234)
Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. (2002) (233)
Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems. (1997) (233)
Central Role of Ferrous/Ferric Iron in the Ultraviolet B Irradiation-mediated Signaling Pathway Leading to Increased Interstitial Collagenase (Matrix-degrading Metalloprotease (MMP)-1) and Stromelysin-1 (MMP-3) mRNA Levels in Cultured Human Dermal Fibroblasts* (1998) (230)
Increased biliary glutathione disulfide release in chronically ethanol‐treated rats (1979) (229)
Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems. (1984) (229)
Cranberries and Their Bioactive Constituents in Human Health12 (2013) (228)
Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. (1999) (225)
Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. (2003) (225)
Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. (1995) (222)
Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes. (2001) (221)
Antioxidant Defense: Vitamins E and C and Carotenoids (1997) (220)
Cocoa polyphenols and inflammatory mediators. (2005) (218)
Dietary selenium in adjuvant therapy of viral and bacterial infections. (2015) (216)
Oxidation of glutathione by the superoxide radical to the disulfide and the sulfonate yielding singlet oxygen. (1983) (216)
Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation (1981) (215)
Dietary tomato paste protects against ultraviolet light-induced erythema in humans. (2001) (215)
Preferential Relative Porphyrin Enrichment in Solar Keratoses upon Topical Application of ^‐Aminolevulinic Acid Methylester (1998) (215)
Role of reactive oxygen species in biological processes (1991) (214)
Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite. (1997) (213)
Polyphenols and health: update and perspectives. (2010) (213)
Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene. (1996) (212)
Profiles of antioxidants in human plasma. (2001) (211)
Sustained Increase in Flow-Mediated Dilation After Daily Intake of High-Flavanol Cocoa Drink Over 1 Week (2007) (210)
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. (1987) (207)
The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems. (1978) (206)
Glutathione disulfide (GSSG) efflux from cells and tissues. (1984) (203)
Peroxisomes in Biology and Medicine (1987) (195)
Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi. (1980) (188)
Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema. (2005) (187)
Cardiac transport of glutathione disulfide and S-conjugate. Studies with isolated perfused rat heart during hydroperoxide metabolism. (1984) (186)
Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: In vitro and in vivo studies (2000) (185)
Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching. (1997) (185)
β-Carotene and other carotenoids in protection from sunlight. (2012) (184)
S-nitrosylation and S-glutathiolation of protein sulfhydryls by S-nitroso glutathione. (1999) (181)
Lycopene: Antioxidant and Biological Effects and its Bioavailability in the Human (1998) (181)
Hepatic mitochondrial and cytosolic glutathione content and the subcellular distribution of GSH‐S‐transferases (1979) (179)
Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity. (1983) (178)
Carotenoids and Protection against Solar UV Radiation (2002) (174)
Stimulation of gap junctional communication: comparison of acyclo-retinoic acid and lycopene. (2000) (172)
Carotenoids in Health and Disease (2004) (170)
Glutathione Conjugation: Mechanisms and Biological Significance (1989) (170)
Role of reactive oxygen species in cell toxicity. (1992) (170)
Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence on alpha-tocopherol. (1989) (169)
Flavanol-rich cocoa drink lowers plasma F(2)-isoprostane concentrations in humans. (2004) (168)
Reduced and oxidized glutathione efflux from liver (1978) (168)
High selenium intake and increased diabetes risk: experimental evidence for interplay between selenium and carbohydrate metabolism (2010) (168)
Protection by selenoprotein P in human plasma against peroxynitrite-mediated oxidation and nitration. (1998) (168)
Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women. (2006) (165)
Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart. (1986) (165)
Singlet oxygen induced DNA damage. (1992) (164)
The reaction of ebselen with peroxynitrite. (1996) (162)
Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignancies. (1997) (161)
Functions of Glutathione in Liver and Kidney (1978) (160)
Lycopene-rich products and dietary photoprotection. (2006) (159)
Protection against peroxynitrite by cocoa polyphenol oligomers (1999) (159)
Selenium homeostasis and antioxidant selenoproteins in brain: implications for disorders in the central nervous system. (2013) (158)
DNA damage by peroxynitrite characterized with DNA repair enzymes. (1996) (158)
Low level chemiluminescence of liver microsomal fractions initiated by tert-butyl hydroperoxide. Relation to microsomal hemoproteins, oxygen dependence, and lipid peroxidation. (2005) (158)
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology (2022) (157)
State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver. (1972) (157)
The early research and development of ebselen. (2013) (156)
Kinetic study of the reaction of ebselen with peroxynitrite (1996) (155)
Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene. (1998) (155)
On the history of oxidative stress: Concept and some aspects of current development (2018) (155)
Astaxanthin, canthaxanthin and β‐carotene differently affect UVA‐induced oxidative damage and expression of oxidative stress‐responsive enzymes (2009) (154)
Carotenoids and Flavonoids Contribute to Nutritional Protection against Skin Damage from Sunlight (2007) (154)
Physical and chemical scavenging of singlet molecular oxygen by tocopherols. (1990) (154)
Lycopene oxidation product enhances gap junctional communication. (2003) (153)
Activity of thiols as singlet molecular oxygen quenchers. (1991) (153)
Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. (2006) (152)
Separation of beta-carotene and lycopene geometrical isomers in biological samples. (1993) (152)
(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase. (2007) (152)
Role of tocopherols in the protection of biological systems against oxidative damage. (1991) (152)
Singlet oxygen induces collagenase expression in human skin fibroblasts (1993) (150)
Defenses against peroxynitrite: selenocompounds and flavonoids. (2003) (148)
Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia. (2005) (147)
Singlet oxygen-induced signaling effects in mammalian cells. (2003) (147)
A novel biologically active selenoorganic compound--IV. Protective glutathione-dependent effect of PZ 51 (ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes. (1985) (146)
Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase. (2002) (141)
Singlet molecular oxygen production in the reaction of peroxynitrite with hydrogen peroxide (1994) (140)
Hepatic thiol and glutathione efflux under the influence of vasopressin, phenylephrine and adrenaline. (1985) (139)
High fruit and vegetable intake is positively correlated with antioxidant status and cognitive performance in healthy subjects. (2009) (138)
Polyphenols of Cocoa: Inhibition of Mammalian 15-Lipoxygenase (2001) (138)
Quantification of singlet oxygen generated by thermolysis of 3,3'-(1,4-naphthylene)dipropionate endoperoxide. Monomol and dimol photoemission and the effects of 1,4-diazabicyclo[2.2.2]octane (1989) (135)
Role of alcohol dehydrogenase activity and the acetaldehyde in ethanol- induced ethane and pentane production by isolated perfused rat liver. (1982) (135)
The steady state level of catalase compound I in isolated hemoglobin‐free perfused rat liver (1970) (135)
Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics. (2000) (131)
4 – Hydroperoxides and Thiol Oxidants in the Study of Oxidative Stress in Intact Cells and Organs (1985) (129)
The lag phase. (1998) (128)
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts. (2000) (127)
Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways. (2002) (127)
Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo. (2008) (127)
Glutamine Metabolism in Mammalian Tissues (1984) (127)
Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. (1999) (127)
Ebselen prevents early alcohol-induced liver injury in rats. (2001) (126)
Plasma levels of lipophilic antioxidants in very old patients with Type 2 diabetes (2000) (125)
Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation (1999) (124)
Selenoprotein P expression is controlled through interaction of the coactivator PGC‐1α with FoxO1a and hepatocyte nuclear factor 4α transcription factors (2008) (124)
Reactive oxygen species associated with cell differentiation in Neurospora crassa. (1993) (124)
Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease. (1994) (123)
Antioxidant and redox regulation of genes (1999) (122)
Plasma Antioxidant Status, Immunoglobulin G Oxidation and Lipid Peroxidation in Demented Patients: Relevance to Alzheimer Disease and Vascular Dementia (2004) (122)
Damage to plasmid DNA by singlet oxygen and its protection. (1993) (121)
Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite. (1996) (120)
ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver. (1991) (120)
Physical Quenching of Singlet Oxygen and cis‐trans Isomerization of Carotenoids a (1993) (120)
Attenuation of oxidation and nitration reactions of peroxynitrite by selenomethionine, selenocystine and ebselen. (1996) (119)
Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat. (1982) (119)
Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite. (2001) (118)
Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species (2006) (117)
Oxidative stress: excited oxygen species and enzyme activity. (1985) (115)
Xanthophyll esters in human skin. (1998) (113)
Visible-range low-level chemiluminescence in biological systems. (1990) (112)
Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity (2006) (112)
Oxidative Stress: Concept and Some Practical Aspects (2020) (111)
Non‐enzymatic triggering of the ceramide signalling cascade by solar UVA radiation (2000) (111)
Regulation of flux through glutaminase and glutamine synthetase in isolated perfused rat liver. (1983) (111)
Plasma levels of vitamin E and carotenoids are decreased in patients with nonalcoholic steatohepatitis (NASH) (2011) (111)
Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species. (2002) (110)
All-trans beta-carotene preferentially accumulates in human chylomicrons and very low density lipoproteins compared with the 9-cis geometrical isomer. (1995) (110)
Effects of 4-hydroxynonenal on isolated hepatocytes. Studies on chemiluminescence response, alkane production and glutathione status. (1983) (110)
cis-trans isomers of lycopene and beta-carotene in human serum and tissues. (1992) (109)
Cigarette smoking cessation increases plasma levels of several antioxidant micronutrients and improves resistance towards oxidative challenge (2003) (109)
Plasma Carotenoid and Malondialdehyde Levels in Ischemic Stroke Patients: Relationship to Early Outcome (2002) (109)
On the opinion of the European Commission “Scientific Committee on Food” regarding the tolerable upper intake level of vitamin E (2003) (2005) (108)
Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment. (1991) (106)
A role of mitochondrial glutathione peroxidase in modulating mitochondrial oxidations in liver. (1978) (105)
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections (2020) (105)
Photoprotection by dietary carotenoids: concept, mechanisms, evidence and future development. (2012) (105)
β-Cryptoxanthin Selectively Increases in Human Chylomicrons upon Ingestion of Tangerine Concentrate Rich in β-Cryptoxanthin Esters (1995) (105)
The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen. (1993) (104)
Selenoprotein P Protects Low-density Lipoprotein Against Oxidation (2004) (104)
Vitamin E improves the aminotransferase status of patients suffering from viral hepatitis C: a randomized, double-blind, placebo-controlled study. (1997) (104)
Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks. (1989) (104)
Infrared-A radiation-induced matrix metalloproteinase 1 expression is mediated through extracellular signal-regulated kinase 1/2 activation in human dermal fibroblasts. (2002) (104)
Myeloperoxidase/nitrite‐mediated lipid peroxidation of low‐density lipoprotein as modulated by flavonoids (2003) (104)
4 – Nonenzymatic Antioxidant Defense Systems (1994) (103)
Contribution of nitric oxide synthase to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells. (1991) (101)
Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo. (1981) (101)
Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. (1985) (101)
Singlet oxygen formation detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2. (1983) (100)
Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts (1997) (100)
Kinetic study of the reaction of glutathione peroxidase with peroxynitrite. (1998) (100)
Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver. (1979) (99)
Plasma lipophilic antioxidants and malondialdehyde in congestive heart failure patients: relationship to disease severity. (2002) (99)
Opposite Roles of Selenium-dependent Glutathione Peroxidase-1 in Superoxide Generator Diquat- and Peroxynitrite-induced Apoptosis and Signaling* (2001) (98)
Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT (2012) (97)
Carotenoids and UV protection. (2004) (97)
Anticoccidial and antiinflammatory activity of garlic in murine Eimeria papillata infections. (2011) (96)
Low-level chemiluminescence of isolated hepatocytes. (1981) (95)
Identification of an abundant S-thiolated rat liver protein as carbonic anhydrase III; characterization of S-thiolation and dethiolation reactions☆ (1991) (95)
Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin (2007) (94)
Preferential increase in chylomicron levels of the xanthophylls lutein and zeaxanthin compared to beta-carotene in the human. (1996) (93)
Glutathione efflux from perfused rat liver after phenobarbital treatment, during drug oxidations, and in selenium deficiency. (1978) (93)
Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids. (2001) (92)
Cocoa extract protects against early alcohol-induced liver injury in the rat. (2002) (91)
Hepatic role in pH regulation: role of the intercellular glutamine cycle (1984) (91)
Interaction of peroxynitrite with carotenoids in human low density lipoproteins. (2000) (91)
Inhibition of superoxide and nitric oxide release and protection from reoxygenation injury by ebselen in rat kupffer cells (1992) (90)
Inverse relationship of epidermal growth factor receptor and HER2/neu gene expression in human renal cell carcinoma. (1990) (90)
Evaluation of alpha-tocopherol antioxidant activity in microsomal lipid peroxidation as detected by low-level chemiluminescence. (1984) (89)
Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy. (1998) (89)
Inactivation of viruses by chemically and photochemically generated singlet molecular oxygen. (1995) (89)
Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles. (1984) (88)
Quantification of the α- and γ-Tocopherol Metabolites 2,5,7,8-Tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman and 2,7,8-Trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman in Human Serum (1999) (87)
Competition between transport of glutathione disulfide (GSSG) and glutathione S‐conjugates from perfused rat liver into bile (1982) (87)
Divergent Optimum Levels of Lycopene, β-Carotene and Lutein Protecting Against UVB Irradiation in Human Fibroblasts¶ (2002) (86)
Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver. (1979) (86)
Peroxisomal fatty acid oxidation as detected by H2O2 production in intact perfused rat liver. (1981) (85)
Oxidative eustress: On constant alert for redox homeostasis (2021) (85)
Incorporation of carotenoids from paprika oleoresin into human chylomicrons (2003) (85)
Human serum concentrations of all-trans β- and α-carotene but not 9-cis β-carotene increase upon ingestion of a natural isomer mixture obtained from Dunaliella salina (Betatene) (1993) (84)
Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite. (1997) (84)
Induction of gap junctional communication by 4-oxoretinoic acid generated from its precursor canthaxanthin. (1995) (82)
Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite. (2001) (82)
Loss of α‐tocopherol upon exposure to nitric oxide or the sydnonimine SIN‐1 (1993) (81)
Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of δ-aminolaevulinic acid (1999) (81)
Heme occupancy of catalase in hemoglobin-free perfused rat liver and of isolated rat liver catalase. (1973) (80)
Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies. (1984) (80)
Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci. (1999) (79)
Assessment of the kidney function in maintenance of plasma glutathione concentration and redox state in anaesthetized rats (1979) (79)
Role of plasma membrane transport in hepatic glutamine metabolism. (1985) (78)
Critical Role of l-Arginine in Endothelial Cell Survival During Oxidative Stress (2003) (78)
Epidermal Growth Factor Receptor Is a Common Mediator of Quinone-induced Signaling Leading to Phosphorylation of Connexin-43 (2003) (78)
Reduction of methionine selenoxide to selenomethionine by glutathione. (1998) (78)
Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture. (2010) (78)
Naphthalene endoperoxides as generators of singlet oxygen in biological media. (2000) (76)
Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects (2005) (76)
Comparing Nitrosative Versus Oxidative Stress toward Zinc Finger-dependent Transcription (2002) (75)
Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. (1982) (74)
Peroxynitrite does not decompose to singlet oxygen (1ΔgO2) and nitroxyl (NO (2000) (73)
Functions of intracellular glutathione in hepatic hydroperoxide and drug metabolism and the role of extracellular glutathione. (1980) (72)
The disposition of formaldehyde and formate arising from drug N-demethylations dependent on cytochrome P-450 in hepatocytes and in perfused rat liver. (1978) (71)
Prevention of singlet oxygen-induced DNA damage by lipoate. (1993) (71)
Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity (2003) (70)
Function of thioredoxin reductase as a peroxynitrite reductase using selenocystine or ebselen. (1999) (70)
Transport of glutathione, glutathione disulfide, and glutathione conjugates across the hepatocyte plasma membrane. (1989) (70)
Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver. (1970) (70)
Antioxidant depletion in aortic crossclamping ischemia: Increase of the plasma α-tocopheryl quinone/α-tocopherol ratio (1992) (70)
Inhibitors Tools in Cell Research (1969) (70)
The content of glutathione and glutathione S-transferases and the glutathione peroxidase activity in rat liver nuclei determined by a non-aqueous technique of cell fractionation. (1995) (69)
2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade. (2002) (69)
Even after UVA-exposure will nitric oxide protect cells from reactive oxygen intermediate-mediated apoptosis and necrosis (2001) (69)
Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential. (2003) (69)
Water-soluble organotellurium compounds: catalytic protection against peroxynitrite and release of zinc from metallothionein. (2000) (68)
Toward understanding success and failures in the use of selenium for cancer prevention. (2013) (68)
UVA and singlet oxygen as inducers of cutaneous signaling events. (2001) (68)
Mitochondrial and cytosolic NADPH systems and isocitrate dehydrogenase indicator metabolites during ureogensis from ammonia in isolated rat hepatocytes. (1977) (67)
Glutathione levels in human lens: regional distribution in different forms of cataract. (1990) (67)
Towards identifying novel anti-Eimeria agents: trace elements, vitamins, and plant-based natural products (2014) (67)
Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite. (2003) (67)
Interaction of the pyridoindole stobadine with peroxyl, superoxide and chromanoxyl radicals. (1993) (67)
Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin. (2007) (66)
Distinct temporal relation among oxygen uptake, malondialdehyde formation, and low-level chemiluminescence during microsomal lipid peroxidation. (1987) (66)
Reactions of peroxynitrite with cocoa procyanidin oligomers. (2000) (66)
Effects of carotenoids and retinoids on gap junctional communication (2001) (66)
Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts (1996) (65)
Nitrite, a naturally occurring precursor of nitric oxide that acts like a ‘prodrug’ (2006) (65)
A novel biologically active selenooorganic compound--VII. Biotransformation of ebselen in perfused rat liver. (1988) (63)
Endothelial Function, Nitric Oxide, and Cocoa Flavanols (2006) (63)
Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions. (2006) (63)
Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression (2007) (63)
Activation of pyruvate dehydrogenase during metabolism of ammonium ions in hemoglobin-free perfused rat liver. (1975) (62)
Protein S-thiolation and regulation of microsomal glutathione transferase activity by the glutathione redox couple. (1996) (62)
Effect of age and ambient temperature on n-pentane production in adult housefly, Musca domestica (1985) (61)
Antioxidant vitamins in prevention. (1997) (60)
Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions. (1998) (60)
Antioxidant effect of diethyldithiocarbamate on microsomal lipid peroxidation assessed by low‐level chemiluminescence and alkane production (1983) (60)
Xanthine oxidase is not responsible for reoxygenation injury in isolated-perfused rat heart. (1987) (60)
Loss of transforming activity of plasmid DNA (pBR322) in E. coli caused by singlet molecular oxygen (1987) (60)
Oxygen dependence and subcellular partitioning of hepatic menadione-mediated oxygen uptake. Studies with isolated hepatocytes, mitochondria, and microsomes from rat liver in an oxystat system. (1985) (60)
Oxygen gradients during hypoxic steady states in liver. Urate oxidase and cytochrome oxidase as intracellular O2 indicators. (1977) (60)
Biochemistry of the peroxisome in the liver cell. (1974) (59)
Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidation. (1992) (59)
Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs. (2012) (59)
Modifications of Glyceraldehyde-3-Phosphate Dehydrogenase Induced by Increasing Concentrations of Peroxynitrite: Early Recognition by 20S Proteasome (2003) (59)
Binding of Selenoprotein P to Heparin: Characterization with Surface Plasmon Resonance (2000) (58)
Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase. (2005) (58)
PHYSIOLOGICAL SOCIETY SYMPOSIUM: IMPAIRED ENDOTHELIAL AND SMOOTH MUSCLE CELL FUNCTION IN OXIDATIVE STRESS OXIDATIVE STRESS: OXIDANTS AND ANTIOXIDANTS (2011) (58)
SHORT COMMUNICATION: Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear vitamin D receptor (1996) (58)
Non-nutritive bioactive constituents of plants: lycopene, lutein and zeaxanthin. (2003) (58)
Phosphorylase and creatine kinase modification by thiol-disulfide exchange and by xanthine oxidase-initiated S-thiolation. (1990) (57)
Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence. (1998) (57)
Hepatic lipoate uptake. (1989) (57)
Distribution of the monochlorobimane-glutathione conjugate between nucleus and cytosol in isolated hepatocytes. (1993) (57)
UVA-mediated downregulation of MMP-2 and MMP-9 in human epidermal keratinocytes. (2003) (57)
Defenses against peroxynitrite. (1996) (56)
Antioxidant activity of the pyridoindole stobadine. Pulse radiolytic characterization of one-electron-oxidized stobadine and quenching of singlet molecular oxygen. (1992) (56)
Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts (1996) (56)
[40] Assay of lycopene and other carotenoids as singlet oxygen quenchers (1992) (55)
Human fibroblasts release reactive oxygen species in response to treatment with synovial fluids from patients suffering from arthritis. (1990) (55)
Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis. (2004) (55)
Plasma micronutrient status is improved after a 3-month dietary intervention with 5 daily portions of fruits and vegetables: implications for optimal antioxidant levels (2009) (54)
The use of total antioxidant capacity as surrogate marker for food quality and its effect on health is to be discouraged. (2014) (54)
Mutagenicity of nitroxide-free radicals. (1986) (53)
The role of carotenoids and retinoids in gap junctional communication. (1998) (53)
Drug oxidations dependent on cytochrome P-450 in isolated hepatocytes. The role of the tricarboxylates and the aminotransferases in NADPH supply. (1977) (53)
Efficacy of all-trans-beta-carotene, canthaxanthin, and all-trans-, 9-cis-, and 4-oxoretinoic acids in inducing differentiation of an F9 embryonal carcinoma RAR beta-lacZ reporter cell line. (1995) (53)
Energy‐linked cardiac transport system for glutathione disulfide (1986) (53)
Intervention with flaxseed and borage oil supplements modulates skin condition in women. (2008) (52)
Ebselen: a glutathione peroxidase mimic. (1994) (52)
The present status of antioxidant vitamins and beta-carotene. (1995) (52)
Divergent Optimum Levels of Lycopene, β‐Carotene and Lutein Protecting Against UVB Irradiation in Human Fibroblasts ¶ (2002) (52)
Fruit Juice Carotenol Fatty Acid Esters and Carotenoids As Identified by Matrix-Assisted Laser Desorption Ionization (MALDI) Mass Spectrometry† (1996) (51)
Direct protective effect of NAD(P)H:quinone reductase against menadione-induced chemiluminescence of postmitochondrial fractions of mouse liver. (1987) (51)
Carotenoids and intercellular communication via gap junctions. (1997) (51)
Selective para hydroxylation of phenol and aniline by singlet molecular oxygen. (1993) (51)
Human fibroblasts release low amounts of reactive oxygen species in response to the potent phagocyte stimulants, serum-treated zymosan, N-formyl-methionyl-leucyl-phenylalanine, leukotriene B4 or 12-O-tetradecanoylphorbol 13-acetate. (1990) (51)
Interaction of ebselen with glutathione S-transferase and papain in vitro. (1994) (51)
Mitochondrial Nicotinamide Nucleotide Systems: Ammonium Chloride Responses and Associated Metabolic Transitions in Hemoglobin-Free Perfused Rat Liver (2009) (50)
Responses to Peroxynitrite in Yeast: Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) as a Sensitive Intracellular Target for Nitration and Enhancement of Chaperone Expression and Ubiquitination (2000) (50)
Singlet oxygen induced single-strand breaks in plasmid pBR322 DNA: the enhancing effect of thiols. (1991) (49)
Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line. (1994) (49)
Attenuation of hepatic expression and secretion of selenoprotein P by metformin. (2009) (49)
Thioredoxin secreted upon ultraviolet A irradiation modulates activities of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in human dermal fibroblasts. (2004) (48)
Biological Redox Systems and Oxidative Stress (2007) (48)
Hormones, glutathione status and protein S-thiolation. (1987) (48)
A new parameter for sex education (1988) (48)
Irradiation of Cells with Ultraviolet-A (320-400 nm) in the Presence of Cell Culture Medium Elicits Biological Effects Due to Extracellular Generation of Hydrogen Peroxide (2003) (48)
Antioxidant activity in cells and organs. (1987) (47)
Thyroid Hormone Receptors Bind to an Element in the Connexin43 Promoter (2000) (47)
Transport of ebselen in plasma and its transfer to binding sites in the hepatocyte. (1994) (47)
Specific S-thiolation of a 30-kDa cytosolic protein from rat liver under oxidative stress. (1989) (47)
Induction of Glutathione Peroxidase 4 Expression during Enterocytic Cell Differentiation* (2011) (47)
Tetramethyl‐Ortho‐quinodimethane, First Member of a Family of Custom‐Tailored Cheletropic Spin Traps for Nitric Oxide (1992) (47)
Excited singlet molecular O2 (1Δg) is generated enzymatically from excited carbonyls in the dark (2014) (46)
Oxene donors yield low-level chemiluminescence with microsomes and isolated cytochrome P-450. (2005) (45)
Elevated Lipid Peroxidation Biomarkers and Low Antioxidant Status in Atherosclerotic Patients with Increased Carotid or Iliofemoral Intima Media Thickness (2007) (45)
Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. (1984) (45)
The presence of nitrite during UVA irradiation protects from apoptosis (2003) (45)
HuR regulates gap junctional intercellular communication by controlling β‐catenin levels and adherens junction integrity (2009) (45)
Protection against Peroxynitrite by Selenoproteins (1998) (45)
Interplay between the chalcone cardamonin and selenium in the biosynthesis of Nrf2-regulated antioxidant enzymes in intestinal Caco-2 cells. (2016) (44)
Hepatic calcium efflux during cytochrome P-450-dependent drug oxidations at the endoplasmic reticulum in intact liver. (1981) (44)
Protection against reactive oxygen species by NAD(P)H:quinone reductase induced by the dietary antioxidant butylated hydroxyanisole (BHA) (1984) (44)
Decreased flux through pyruvate dehydrogenase by thiol oxidation during t-butyl hydroperoxide metabolism in perfused rat liver. (1983) (44)
Perivascular nerve stimulation and phenylephrine responses in rat liver. Metabolic effects, Ca2+ and K+ fluxes. (1987) (44)
Singlet Oxygen Quenching Abilities of Carotenoids (1997) (44)
Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation (2004) (44)
Subcellular glutathione contents in isolated hepatocytes treated with L-buthionine sulfoximine. (1984) (43)
Antioxidant activity of 5-hydroxytryptophan, 5-hydroxyindole, and DOPA against microsomal lipid peroxidation and its dependence on vitamin E. (1989) (43)
CHAPTER 7 – Biological Basis of Detoxication of Oxygen Free Radicals* (1983) (43)
Delaying of insulin signal transduction in skeletal muscle cells by selenium compounds. (2011) (43)
Diminished plasma levels of vitamin E in patients with severe viral hepatitis. (1996) (43)
Identification of an abundant S-thiolated rat liver protein as carbonic anhydrase III; characterization of S-thiolation and dethiolation reactions. (1990) (42)
Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts. (2002) (42)
Hepatic encephalopathy: clinical aspects and pathogenetic concept. (2013) (42)
The effect of urea synthesis on extracellular pH in isolated perfused rat liver. (1986) (42)
Assay of ethane and pentane from isolated organs and cells. (1984) (42)
Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction. (2010) (42)
Disturbed Redox Homeostasis in Oxidative Distress: A Molecular Link From Chronic Psychosocial Work Stress to Coronary Heart Disease? (2017) (41)
Enhancement of gap junctional communication and connexin43 expression by thyroid hormones. (1998) (41)
Biliary transport of glutathione disulfide studied with isolated rat-liver canalicular-membrane vesicles. (1984) (41)
Low- and high-Km transport of dinitrophenyl glutathione in inside out vesicles from human erythrocytes. (1992) (40)
Singlet oxygen quenching by carotenoids. (1994) (40)
Decreased expression of the glutathione S-transferases alpha and pi genes in human renal cell carcinoma. (1990) (40)
pH control of hepatic glutamine degradation. Role of transport. (1987) (40)
Paraquat-induced chemiluminescence of microsomal fractions. (1983) (39)
Antioxidant systems : the role of carotenoids, tocopherols, and thiols (1991) (39)
Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine (2006) (39)
Analysis of carotenoids and carotenol fatty acid esters by matrix-assisted laser desorption ionization (MALDI) and MALDI-post-source-decay mass spectrometry. (1996) (39)
Expression of NAD(P)H:quinone oxidoreductase and glutathione S-transferases alpha and pi in human renal cell carcinoma and in kidney cancer-derived cell lines. (1994) (39)
Porphyrins Preferentially Accumulate in a Melanoma Following Intravenous Injection of 5-Aminolevulinic Acid (1997) (39)
COVID-19 mortality as a fingerprint of biological age (2021) (39)
Localization and regulation of pancreatic selenoprotein P. (2012) (39)
SypHer3s: a genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range. (2018) (38)
SINGLET OXYGEN INDUCED DNA DAMAGE AND MUTAGENICITY IN A SINGLE‐STRANDED SV40‐BASED SHUTTLE VECTOR (1992) (38)
Evidence for a posttranscriptional effect of retinoic acid on connexin43 gene expression via the 3′‐untranslated region (1997) (38)
Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear vitamin D receptor. (1996) (38)
Lowered amounts of the tissue-specific transcription factor LFB1 (HNF1) correlate with decreased levels of glutathione S-transferase alpha messenger RNA in human renal cell carcinoma. (1994) (37)
Singlet oxygen, UV-A, and ozone (2000) (37)
Astaxanthin diminishes gap junctional intercellular communication in primary human fibroblasts. (2005) (37)
Effect of phenylephrine on glutamate and glutamine metabolism in isolated perfused rat liver. (1984) (37)
Cytochrome P-450, reductive metabolism, and cell injury. (1989) (37)
Strategies of Antioxidant Defense: Relations to Oxidative Stress (1995) (37)
In Vitro Antioxidant Activity of 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman (α-CEHC), a Vitamin E Metabolite (2002) (36)
SINGLET MOLECULAR OXYGEN INDUCED MUTAGENICITY IN A MAMMALIAN SV40‐BASED SHUTTLE VECTOR (1990) (36)
Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7beta-hydroxycholesterol to 7-ketocholesterol ratio. (2006) (36)
Reactivity of ebselen and related selenoorganic compounds with 1,2-dichloroethane radical cations and halogenated peroxyl radicals. (1990) (36)
High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation. (2001) (35)
Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase (2005) (35)
Mitochondrial and cytosolic ATP/ADP ratios in isolated hepatocytes. A comparison of the digitonin method and the non-aqueous fractionation procedure. (1980) (35)
SYNTHETIC CAROTENOIDS, NOVEL POLYENE POLYKETONES AND NEW CAPSORUBIN ISOMERS AS EFFICIENT QUENCHERS OF SINGLET MOLECULAR OXYGEN (1992) (35)
Oxidation of cytochrome b5 by hydroperoxides in rat liver. (1975) (35)
Relation between glutathione redox changes and biliary excretion of taurocholate in perfused rat liver. (1984) (34)
Temporal relationships between the loss of vitamin E, protein sulfhydryls and lipid peroxidation in microsomes challenged with different prooxidants. (1990) (34)
Inhibition of biliary taurocholate excretion during menadione metabolism in perfused rat liver. (1988) (33)
Relationship between free radicals and vitamins: an overview. (1989) (33)
Oxidative damage to mitochondria and protection by ebselen and other antioxidants. (1990) (33)
Myeloperoxidase-mediated LDL oxidation and endothelial cell toxicity of oxidized LDL: attenuation by (−)-epicatechin (2006) (33)
The reaction of 2-(methylseleno)benzanilide with peroxynitrite. (1996) (33)
Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver. (1987) (32)
Protein S-thiolation and redox regulation of membrane-bound glutathione transferase. (1998) (32)
Glutathione Efflux from Perfused Rat Liver and Its Relation to Glutathione Uptake by the Kidney (1978) (32)
Cellular redox changes and response to drugs and toxic agents. (1983) (32)
(-)-Epicatechin effects in rat liver epithelial cells: stimulation of gap junctional communication and counteraction of its loss due to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. (2002) (32)
Microsomal formation of S-nitrosoglutathione from organic nitrites: possible role of membrane-bound glutathione transferase. (1996) (32)
Antioxidant activity of ebselen and related selenoorganic compounds in microsomal lipid peroxidation. (1990) (32)
Hydroperoxide Metabolism: An Overview (1978) (32)
Hepatic Glutamine and Ammonia Metabolism (1984) (31)
Tocopherol metabolites 2, 5, 7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman (α-CEHC) and 2, 7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (γ-CEHC) in human serum after a single dose of natural vitamin E (2002) (31)
Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum. (1999) (31)
The 5-aminolevulinic acid-induced porphyrin biosynthesis in benign and malignant cells of the skin. (2001) (31)
Organic anions exhibit distinct inhibition patterns on the low-Km and high-Km transport of S-(2,4-dinitrophenyl)glutathione through the human erythrocyte membrane. (1993) (31)
Ethane production by isolated perfused rat liver: a system to study metabolic effects related to lipid peroxidation. (1981) (31)
A process requiring mitochondrial NADPH: Urea formation from ammonia (1975) (30)
Antioxidant action of stobadine. (1994) (30)
Carotenoid-containing unilamellar liposomes loaded with glutathione: a model to study hydrophobic-hydrophilic antioxidant interaction (2000) (30)
Properties of Glutathione Disulfide (GSSG) and Glutathione-S-Conjugate Release from Perfused Rat Liver (1978) (30)
Activation of ErbB2 by 2‐methyl‐1,4‐naphthoquinone (menadione) in human keratinocytes: Role of EGFR and protein tyrosine phosphatases (2006) (30)
(-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments. (2001) (30)
The role of pH and the lack of a requirement for hydorgencarbonate in the regulation of hepatic glutamine metabolism. (1980) (30)
Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation. (2004) (30)
Adjacent guanines as preferred sites for strand breaks in plasmid DNA irradiated with 193 nm and 248 nm UV laser light. (1996) (30)
Mitogen-activated protein kinase activation by singlet oxygen and ultraviolet A. (2000) (29)
Reduction kinetics and content of cytochrome P‐450 by application of dual wavelength techniques to hemoglobin‐free perfused rat liver (1969) (29)
Myeloperoxidase‐induced lipid peroxidation of LDL in the presence of nitrite. Protection by cocoa flavanols (2005) (29)
NADPH-dependent oxidation of reduced ebselen, 2-selenylbenzanilide, and of 2-(methylseleno)benzanilide catalyzed by pig liver flavin-containing monooxygenase. (1992) (29)
Molecular Aspects of Inflammation (1992) (29)
Gene structure and regulation of expression of human glutathione S-transferases alpha. (1994) (29)
Vitamin D influences gap junctional communication in C3H/10T 1/2 murine fibroblast cells (1994) (29)
Direct evidence that (−)-epicatechin increases nitric oxide levels in human endothelial cells (2011) (29)
Ultraviolet A induced modulation of gap junctional intercellular communication by P38 MAPK activation in human keratinocytes (2008) (28)
Rise of coenzyme A-glutathione mixed disulfide during hydroperoxide metabolism in perfused rat liver. (2005) (28)
Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human skin fibroblasts. (1997) (28)
Findings in redox biology: From H2O2 to oxidative stress (2020) (28)
An Encapsulated Fruit and Vegetable Juice Concentrate Increases Skin Microcirculation in Healthy Women (2011) (28)
Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite (2004) (28)
Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes (2018) (27)
Carbon-dioxide concentration and the distribution of monocarboxylate and H+ ions between intracellular and extracellular spaces of hemoglobin-free perfused rat liver. (1973) (27)
Biological significance of active oxygen species: in vitro studies on singlet oxygen-induced DNA damage and on the singlet oxygen quenching ability of carotenoids, tocopherols and thiols. (1991) (27)
Measurement of hydrogen peroxide formation in situ. (1981) (27)
Excited species generation in horseradish peroxidase-mediated oxidation of glutathione. (1985) (26)
Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells (2005) (26)
Positive increase of redox potential of the extramitochondrial NADP(H) system by mixed function oxidations in hemoglobin‐free perfused rat liver (1970) (26)
Decomposition of S-nitrosocysteine via S- to N-transnitrosation. (2007) (25)
Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation. (2006) (25)
Eimeria papillata: upregulation of specific miRNA-species in the mouse jejunum. (2011) (25)
Biochemistry of Oxidative Stress: Recent Experimental Work (1988) (25)
Kinetic evidence for rapid oxidation of (-)-epicatechin by human myeloperoxidase. (2008) (25)
Ebselen lowers plasma interleukin-6 levels and glial heme oxygenase-1 expression after focal photothrombotic brain ischemia. (2000) (25)
The isozyme pattern of glutathione S‐transferases in rat heart (1984) (25)
Steady state relaxation of enolase in vitro and metabolic throughput in vivo of red and white rabbit muscles. (1969) (25)
Carotenoids in human skin: noninvasive measurement and identification of dermal carotenoids and carotenol esters. (2000) (24)
Hepatic Transport of Organic Substances (1989) (24)
β-Carotene serum levels in patients with erythropoietic protoporphyria on treatment with the synthetic all-trans isomer or a natural isomeric mixture of β-carotene (1996) (24)
Effect of DABCO (1,4‐diazabicyclo[2,2,2]‐octane) on singlet oxygen monomol (1270 nm) and dimol (634 and 703 nm) emission (1983) (24)
Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen. (1994) (23)
Cloning, sequencing and characterization of the human alpha glutathione S-transferase gene corresponding to the cDNA clone pGTH2. (1992) (23)
Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs (2012) (23)
Synthetic carotenoids, novel polyene polyketones and new capsorubin isomers as efficient quenchers of singlet molecular oxygen. (1992) (23)
Cholestasis and changes of portal pressure caused by chlorpromazine in the perfused rat liver (1991) (23)
Protection by flavanol-rich foods against vascular dysfunction and oxidative damage: 27th Hohenheim Consensus Conference. (2012) (23)
Mechanism and relevance of glutathione mutagenicity. (1986) (23)
Generation of excited species catalyzed by horseradish peroxidase or hemin in the presence of reduced glutathione and H2O2. (1987) (23)
One-electron reduction of selenomethionine oxide (2000) (23)
Analysis of cellular electron transport systems in liver and other organs by absorbance and fluorescence techniques. (1980) (23)
ATP-stimulated uptake of S-(2,4-dinitrophenyl)glutathione by plasma membrane vesicles from rat liver. (1989) (23)
Increase of β‐actin mRNA upon hypotonic perfusion of perfused rat liver (1991) (23)
Effects of vitamin C and aspirin in ischemic stroke‐related lipid peroxidation: Results of the AVASAS (Aspirin Versus Ascorbic acid plus Aspirin in Stroke) Study (2005) (23)
Decreased flux through pyruvate dehydrogenase during calcium ion movements induced by vasopressin, alpha-adrenergic agonists and the ionophore A23187 in perfused rat liver. (1983) (23)
Antioxidant activity of the pyridoindole stobadine in liposomal and microsomal lipid peroxidation. (1992) (23)
Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts. (2004) (22)
Ozone in arteriosclerotic plaques: searching for the "smoking gun". (2004) (22)
Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance (2010) (22)
Energy dependence of enzyme release from hypoxic isolated perfused rat heart tissue. (1988) (22)
Peroxisomal enzymes and oxygen metabolism in liver. (1977) (22)
Alcohol, aldehydes and lipid peroxidation: current notions. (1987) (22)
Hepatic uptake of cadmium and its biliary release as affected by dithioerythritol and glutathione. (1984) (21)
13 – Carotenoids: Occurrence, Biochemical Activities, and Bioavailability (1999) (21)
Glutathione S-transferases in human testicular germ cell tumors: changes of expression and activity. (1992) (21)
Post-translational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells (2007) (21)
Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation. (2005) (21)
A synthetic C22 carotenoid inhibits carcinogen-induced neoplastic transformation and enhances gap junctional communication. (1993) (20)
Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics. (2005) (20)
Quantification of Singlet Oxygen Generated by Thermolysis of 3,3′-(1,4-Naphthylidene)dipropionate. Monomol and Dimol Photoemission and the Effects of 1,4-Diazabicyclo(2.2.2)octane. (1989) (20)
Peroxynitrite Diminishes Gap Junctional Communication: Protection by Selenite Supplementation (1999) (20)
Ethane release during metabolism of aldehydes and monoamines in perfused rat liver. (1983) (19)
Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factor(s) generated by squamous tumor cells. (2003) (19)
Analysis of connexin43 gene expression induced by retinoic acid in F9 teratocarcinoma cells (1996) (19)
Selenenyl iodide: a new substrate for mammalian thioredoxin reductase. (2003) (19)
Optical spectral studies of ebselen interaction with cytochrome P-450 of rat liver microsomes. (1989) (19)
Biological activities of Apo-canthaxanthinoic acids related to gap junctional communication. (1999) (19)
Inhibition of pyruvate dehydrogenase during the metabolism of glutamine and proline in hemoglobin-free perfused rat liver. (1982) (19)
Rac upregulates tissue inhibitor of metalloproteinase‐1 expression by redox‐dependent activation of extracellular signal‐regulated kinase signaling (2006) (19)
[45] Transport of glutathione disulfide and glutathione S-conjugates in Hepatocyte plasma membrane vesicles (1994) (19)
Hepatic mercapturic acid formation: involvement of cytosolic cysteinylglycine S-conjugate dipeptidase activity. (1998) (18)
Compartmentation of high-energy phosphates in resting and working rat skeletal muscle. (1984) (18)
Osmosensing and osmosignaling (2007) (18)
Solar-simulated radiation induces secretion of IL-6 and production of isoprostanes in human skin in vivo (2006) (18)
Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide (1987) (18)
THE PEROXIDASE/OXIDASE ACTIVITY OF SOYBEAN LIPOXYGENASE – II. TRIPLET CARBONYLS AND RED PHOTOEMISSION DURING POLYUNSATURATED FATTY ACID AND GLUTATHIONE OXIDATION (1989) (18)
Predisposition towards urolithiasis associated with the NQO1 null-allele. (1998) (18)
Active oxygen metabolites and their action in the hepatocyte. Studies on chemiluminescence responses and alkane production. (1982) (18)
Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome (2007) (18)
Formation of electronically excited states during the oxidation of arachidonic acid by prostaglandin endoperoxide synthase. (2000) (17)
Ultraviolet-A irradiation but not ultraviolet-B or infrared-A irradiation leads to a disturbed zinc homeostasis in cells. (2008) (17)
Formation of singlet oxygen in the thermal decomposition of 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane, a chemical source of triplet-excited ketones. (1996) (17)
Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs. (1987) (17)
Assessment of the C-525 laser dye as a chemiluminescence sensitizer for lipid peroxidation in biological membranes: a comparison with chlorophyll-a. (1996) (17)
Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells. (2007) (17)
Protein S-Thiolation, S-Nitrosylation, and Irreversible Sulfhydryl Oxidation: Roles in Redox Regulation (2003) (17)
On the state of mitochondria in perfused liver: Action of sodium azide on respiratory carriers and respiration (1969) (16)
Hypochlorite destroys carotenoids in low density lipoproteins thus decreasing their resistance to peroxidative modification. (1997) (16)
Radiation Hormesis: The Link to Nanomolar Hydrogen Peroxide. (2017) (16)
Ca2+ mobilization by vasopressin and glucagon in perfused livers. Effect of prior intoxication with bromotrichloromethane. (1989) (16)
Separation of retinoic acid all-trans, mono-cis and poly-cis isomers by reversed-phase high-performance liquid chromatography (1993) (16)
Dietary selenium affects intestinal development of Eimeria papillata in mice (2013) (15)
Inhibition of ethanol- and aldehyde-induced release of ethane from isolated perfused rat liver by pargyline and disulfiram (1983) (15)
Chapter 16 – Metabolism of Organic Hydroperoxides (1982) (15)
Oxidative eustress and oxidative distress: Introductory remarks (2020) (15)
Gluthione transferases and gamma-glutamyl transpeptidases (2005) (15)
Limited availability of l-arginine increases DNA-binding activity of NF-κB and contributes to regulation of iNOS expression (2007) (15)
The major isozyme of rat cardiac glutathione transferases. Its correspondence to hepatic transferase X. (1986) (15)
The reaction of peroxynitrite with tert-butyl hydroperoxide produces singlet molecular oxygen. (1997) (15)
Mutagenic fingerprint of ozone in human cells. (2002) (15)
The properties of the secondary catalase—peroxide complex (Compound II) in the hemoglobin-free perfused rat liver (1973) (15)
The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver. (1995) (15)
Role of carotenoids in antioxidant defense. (1994) (15)
THE PEROXIDASE/OXIDASE ACTIVITY OF SOYBEAN LIPOXYGENASE ‐ I. TRIPLET EXCITED CARBONYLS FROM THE REACTION WITH ISOBUTANAL AND THE EFFECT OF GLUTATHIONE (1989) (15)
Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation. (2008) (15)
Cytochrome oxidase and urate oxidase as intracellular O2 indicators in studies of O2 gradients during hypoxia in liver. (1977) (15)
Intact organ spectrophotometry and single-photon counting (2004) (14)
Antioxidant Effects of Carotenoids: Implication in Photoprotection in Humans (2001) (14)
Cellular Generation of Oxidants: Relation to Oxidative Stress (2009) (14)
Oxygen Radicals and Hydroperoxides in Mammalian Organs: Aspects of Redox Cycling and Hydrogen Peroxide Metabolism (1983) (14)
Generation of photoemissive species during quinone redox cycling. (1986) (14)
Peroxynitrite does not decompose to singlet oxygen ( 1 D gO 2 ) and nitroxyl ( NO 2 ) (2000) (14)
Sulfur-to-nitrogen transnitrosation: transfer of nitric oxide from S-nitroso compounds to diethanolamine and the role of intermediate sulfur-to-sulfur transnitrosation. (2001) (14)
Antioxidant depletion in aortic crossclamping ischemia: increase of the plasma alpha-tocopheryl quinone/alpha-tocopherol ratio. (1992) (14)
Cis/trans ISOMERIZATION OF CAROTENOIDS BY THE TRIPLET CARBONYL SOURCE 3‐HYDROXYMETHYL‐3,4,4‐TRIMETHYL‐1,2‐DIOXETANE * (1993) (14)
Intestinal selenoprotein P in epithelial cells and in plasma cells. (2014) (13)
Functional foods for health promotion: state-of-the-science on dietary flavonoids. Extended abstracts from the 12th Annual Conference on Functional Foods for Health Promotion, April 2009. (2009) (13)
Human serum concentrations of all-trans beta- and alpha-carotene but not 9-cis beta-carotene increase upon ingestion of a natural isomer mixture obtained from Dunaliella salina (Betatene). (1993) (13)
Microsomal metabolism of 2-(methylseleno) benzanilide. (1990) (13)
Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimide. (1993) (13)
Accumulation of the xanthophyll lutein in skin amyloid deposits of systemic amyloidosis (al type). (2001) (13)
CONTROL OF MITOCHONDRIAL ACTIVITY BY METABOLITES IN THE HEMOGLOBIN-FREE PERFUSED LIVER (1972) (13)
Upregulation of the thioredoxin-dependent redox system during differentiation of 3T3-L1 cells to adipocytes (2014) (13)
Enhanced Gamma-Glutamyl Transpeptidase Expression and Superoxide Production in Mpv17-/-Glomerulosclerosis Mice (2001) (13)
beta-Cryptoxanthin selectively increases in human chylomicrons upon ingestion of tangerine concentrate rich in beta-cryptoxanthin esters. (1995) (13)
Metabolism and Disposition of Ebselen (1989) (12)
De novo methylation of transfected CAT gene plasmid constructs in F9 mouse embryonal carcinoma cells. (1992) (12)
[37] Reaction of peroxynitrite and hydrogen peroxide to produce singlet molecular oxygen (1Δg) (1996) (12)
Formation of singlet oxygen in the deoxygenation of heteroarene N-oxides by dimethyldioxirane (1995) (12)
1 - Signaling by Singlet Oxygen in Biological Systems (2000) (12)
Interaction of albumin-bound ebselen with rat liver glutathione S-transferase and microsomal proteins. (1994) (12)
The Concept of Oxidative Stress After 30 Years (2016) (12)
Separation of geometrical isomers of beta-carotene and lycopene. (1994) (12)
Diversity of Selenium Functions in Health and Disease (2015) (12)
Loss of alpha-tocopherol upon exposure to nitric oxide or the sydnonimine SIN-1. (1993) (12)
4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/2 cells. (1996) (12)
Identification of the precursor of singlet oxygen (1O2, 1Δg) involved in the disproportionation of hydrogen peroxide catalyzed by calcium hydroxide (1998) (12)
Action of amobarbital on microsomal and mitochondrial respiratory state in perfused rat liver with and without phenobarbital induction (1969) (12)
Glutathione conjugation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide in the perfused rat liver. (1983) (11)
Alpha‐Tocopherol in Microsomal Lipid Peroxidation a (1989) (11)
Quenching of singlet molecular oxygen by natural furan diterpenes (1997) (11)
b-Carotene and other carotenoids in protection from sunlight 1 – 3 (2012) (11)
Tocopherols, Carotenoids and The Glutathione System (1992) (11)
Effects of 5-azacytidine and methyl-group deficiency on NAD(P)H: quinone oxidoreductase and glutathione S-transferase in liver. (1988) (11)
Chemistry of Biologically Important Synthetic Organoselenium Compounds (2001) (11)
Alkane production by isolated rat heart and lung. (1988) (11)
Oxidative stress: from basic research to clinical medicine. (1994) (11)
Quinones and quinone enzymes (2004) (11)
Positive and negative regulatory regions in promoters of human glutathione transferase alpha genes. (1996) (11)
Ascorbate-dependent capacity of dialysed rat liver cytosol to prevent nonenzymatic lipid peroxidation. (1992) (11)
Carotenoids and tocopherols as antioxidants and singlet oxygen quenchers. (1992) (10)
Flow-mediated dilation reference values for evaluation of endothelial function and cardiovascular health. (2022) (10)
S-(4-azidophenacyl)[35S]glutathione photoaffinity labeling of rat liver plasma membrane-associated proteins. (1989) (10)
Localization of strand breaks in plasmid DNA treated with reactive oxygen species. (1994) (10)
From enzymology in vitro to physiological chemistry in vivo (1980) (10)
Arginase-1 overexpression induces cationic amino acid transporter-1 in psoriasis. (2005) (10)
Chapter 29 - Protection against solar radiation — protective properties of antioxidants (2001) (10)
Lack of effect of long-term glutathione administration on aflatoxin B1-induced hepatoma in male rats. (1985) (10)
Physiological evolution: Genomic redox footprints (2017) (10)
How I Became a Biochemist (2007) (10)
PLASMA LIPID PEROXIDATION AND VITAMIN C STATUS IN HEALTHY CENTENARIANS (1999) (10)
Turnover of glutathione S-transferase alpha mRNAs is accelerated by 12-O-tetradecanoyl phorbol-13-acetate in human hepatoma and colon carcinoma cell lines. (1995) (9)
Purification of rat liver plasma membrane glutathione transferase. (1994) (9)
Direct measurement of the state of the lactate dehydrogenase system in hemoglobin-free perfused rat liver. (1972) (9)
Recent Advances in Nutritional Sciences Nutritional, Dietary and Postprandial Oxidative Stress 1,2 (2005) (9)
Methionine and thyroid hormone effects on 14CO2 exhalation from [dimethylamino‐14 C]aminopyrine in intact phenobarbital‐pretreated rats (1979) (9)
Hepatic glutathione release upon decreases of extracellular calcium concentration. (1986) (9)
Antioxidants and Human Health (1998) (9)
Generation of photoemissive species by mitomycin C redox cycling in rat liver microsomes. (1987) (9)
Subunit specificity and organ distribution of glutathione transferase-catalysed S-nitrosoglutathione formation from alkyl nitrites in the rat. (1997) (9)
Sensitization of Peroxynitrite Chemiluminescence by the Triplet Carbonyl Sensitizer Coumarin‐525. Effect of CO2 (1998) (9)
New Horizons in Carotenoid Research (2005) (8)
REDOX COMPARTMENTATION; A SURVEY WITH EMPHASIS ON CURRENT PROBLEMS (1977) (8)
Effects of hormones on mitochondrial processes. (1989) (8)
Peroxynitrite does not decompose to singlet oxygen ((1)Delta (g)O(2)) andnitroxyl (NO(-)). (2000) (8)
Function dependent changes in the subcellular distribution of high energy phosphates in fast and slow rat skeletal muscles (2004) (8)
[Biochemistry of thiol groups: the role of glutathione]. (1989) (8)
Homeostatic control of redox status and health (2021) (8)
Oxidative stress: impact in redox biology and medicine (2015) (8)
Identification of two activating elements in the proximal promoter region of the human glutathione transferase-A1 and -A2 genes. (1998) (7)
Vitamin C: Its Chemistry and Biochemistry. (Reihe: Royal Society of Chemistry Paperbacks.) Von M. B. Davies, J. Austin und D. A. Partridge. The Royal Society of Chemistry, London, 1991, X, 154 S., Broschur $ 13.50. – ISBN 0‐85186‐333‐7 (1992) (7)
Vitamins and Polyphenols in Systemic Photoprotection (2006) (7)
Quenching of singlet molecular oxygen by tocopherols. (1990) (7)
Generation of low-level chemiluminescence during the metabolism of 1-naphthol by rat liver microsomes. (1984) (7)
Cellular levels of all-trans-beta-carotene under the influence of 9-cis-beta-carotene in FU-5 rat hepatoma cells. (1993) (7)
Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human fetal skin fibroblasts (HFFF2) and in rat liver epithelial cells (WB-F344). (2001) (7)
Biological singlet oxygen quenchers assessed by monomol light emission. (2000) (7)
Comparative toxicology of ozone and t-butyl hydroperoxide on isolated rat lung. (1989) (7)
Reversible conversion of nitroxyl anion to nitric oxide. (2002) (7)
BIOAVAILABILITY OF LYCOPENE (1999) (7)
Catabolism of 5-aminolevulinic acid to CO2 by rat liver mitochondria. (1994) (6)
Free radicals in toxicology: redox cycling and NAD(P)H:quinone oxidoreductase. (1996) (6)
Mitochondrial and cytosolic glutathione after depletion by phorone in isolated hepatocytes (1984) (6)
Arginase-1 overexpression induces Cationic Amino Acid Transporter-1 in Psoriasis (2005) (6)
PEROXISOMAL FUNCTION IN PERFUSED LIVER AS STUDIED BY ORGAN PHOTOMETRY * (1982) (6)
The role of glutathione in hepatic hydroperoxide metabolism. (1982) (6)
Gel electrofocusing method for studying protein S-nitrosylation. (1999) (6)
Heat shock but not cold shock leads to disturbed intracellular zinc homeostasis (2009) (6)
Selectively Addressing Mitochondrial Glutathione and Thioredoxin Redox Systems. (2019) (6)
25 – GLUTATHIONE CONJUGATES: TRANSPORT FROM THE CELL AND INTRACELLULAR EFFECTS (1989) (6)
Proton movement accompanying monocarboxylate permeation in hemoglobin‐free perfused rat liver (1972) (6)
NICOTINAMIDE NUCLEOTIDE SYSTEMS AND DRUG OXIDATION IN THE LIVER CELL (1977) (6)
Carotenoids in Systemic Protection Against Sunburn (2004) (5)
Chemiluminescence : approaches to detecting and determining reactive oxygen species (1990) (5)
Mechanisms of Antioxidant Defense against Nitric Oxide/Peroxynitrite (2000) (5)
Increase of beta-actin mRNA upon hypotonic perfusion of perfused rat liver. (1991) (5)
Increased biliary glutathione disulfide (GSSG) release in chronically ethanol-treated rats. (1980) (5)
Hydroperoxide-induced chemiluminescence in rabbit lungs: role of arachidonic acid enzymes. (1988) (5)
Geometrical isomers of β-carotene and lycopene: in vivo studies with humans. (1994) (5)
[35] Matrix-assisted laser desorption ionization-postsource decay-mass spectrometry (1999) (5)
Phase II conjugation enzymes and transport systems (2005) (5)
Transport of glutathione disulfide and glutathione S-conjugates in hepatocyte plasma membrane vesicles. (1994) (5)
On the Possible Role of Cytochrome B-Type Pigments in Redox Relations Between Mitochondria and Endoplasmic Reticulum (1969) (5)
Enzymatic measurement of adenine and guanine(plus inosine) triphosphates and diphosphates in isolated cells and the mitochondrial matrix compartment obtained from rat liver (1979) (5)
Special Issue: "Polyphenols and health". (2014) (5)
Nutritional protection against photooxidative stress in human skin and eye (2020) (5)
Free radicals in toxicology: Redox cycling and nad(P)H: quinone oxidoreductase (1995) (4)
Superoxide release in fibroblasts by an NADPH oxidase is related to cell cycle and proliferation (1990) (4)
Activation of protein kinase CK 2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase ( matrix metalloproteinase-1 ; MMP-1 ) and stromelysin-1 ( MMP-3 ) protein levels in human dermal fibroblasts (4)
BIOLOGICAL ACTIVITY OF CAROTENOIDS AND THEIR BIOAVAILABILITY IN THE HUMAN ORGANISM (1996) (4)
Beta-carotene serum levels in patients with erythropoietic protoporphyria on treatment with the synthetic all-trans isomer or a natural isomeric mixture of beta-carotene. (1996) (4)
Use of repair endonucleases to assess DNA damage by peroxynitrite. (1999) (4)
Hepatic inositol release upon hormonal stimulation of perfused rat liver. (1988) (4)
Se and Non-Se Glutathione Peroxidases: Enzymology and Cell Physiology (1982) (4)
The state of NADPH-NADP + during mixed-function oxidation of hexobarbital in hemoglobin-free perfused rat liver. (1971) (4)
Selenoprotein P. (2002) (3)
Oxygen biology and hypoxia (2007) (3)
Interorgan Glutathione Transport (1992) (3)
Carotenoids, tocopherols and thiols as biological singlet oxygen quenchers (1990) (3)
The effect of tris(2-chloroethyl)amine on human hemoglobin (1976) (3)
Intracellular and intercellular liver heterogeneity: an overview. (1987) (3)
Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin. (2005) (3)
German-Japanese relationships in biochemistry: a personal perspective (2016) (3)
REACTIVE OXYGEN SPECIES FORMED IN VITRO AND IN CELLS: ROLE OF THIOLS(GSH). (1986) (3)
Reactive oxygen species formed in vitro and in cells: role of thiols (GSH). Model studies with xanthine oxidase and horseradish peroxidase. (1986) (3)
DETOXICATION OF OXYGEN FREE RADICALS (1984) (3)
PORPHYRINS PREFERENTIALLY ACCUMULATION IN A MELANOMA FOLLOWING INTRAVENOUSINJECTION OF 5-AMINOLEVULINIC ACID (1997) (3)
Gap Junctional Intercellular Communication: Carotenoids and Retinoids (2005) (3)
6th COSTAM/SFRR (ASEAN/Malaysia) International Workshop on Micronutrients, Oxidative Stress, and the Environment. (2006) (3)
Restriction of hexobarbital metabolism by t-butyl hydroperoxide in perfused rat liver. (1980) (3)
Oxidative eustress and oxidative distress (2021) (3)
Protein Sensors and Reactive Oxygen Species : Vol. 348, Pt. B: Thiol Enzymes and Proteins (2002) (3)
Electronically excited intermediate from peroxynitrite: evaluation by chemiluminescence and by the isomerization of β-carotene (1998) (2)
82 – Epicatechin and Its Role in Protection of LDL and of Vascular Endothelium (2009) (2)
Cellular hydroperoxide metabolism: the roles of glutathione peroxidases and of catalase in liver. (1981) (2)
Reaction of peroxynitrite and hydrogen peroxide to produce singlet molecular oxygen (1deltag). (1996) (2)
Cloning , sequencing and characterization of the human Alpha glutathione S-transferase gene corresponding to the cDNA clone pGTH 2 (2005) (2)
Singlet oxygen (1O2) mediates the UV-induced synthesis of interstitial collagenase (1994) (2)
Optimum porphyrin formation in skin tumors and psoriatic lesions after topical application of δ-aminolevulinic acid (1998) (2)
Some basic properties of ascorbate-dependent antioxidative-defence factors from rat liver cytosol. (1995) (2)
A New Organ Spectrophotometer for Sensitive Dual-Wavelength Absorbance Measurement and Spectral Scanning of Intact Perfused Organs (1978) (2)
Metabolism of estradiol in isolated perfused rat liver. (1973) (2)
Proceedings: Lack of urea formation by rat liver in hydrogen carbonate-free media. (1974) (2)
Highlight: Oxidative Stress (2002) (2)
Future Directions in Preclinical Vitamin E Research: Panel Discussion A (2004) (2)
Oxidative stress: reactive oxygen species in toxicology and pharmacology (1990) (2)
The 15-kDa Selenoprotein (SEP15) (2015) (2)
Organ absorbance and fluorescence spectrophotometry and its application to oxygen-dependent parameters. (1977) (2)
H2O2 as a central redox signaling molecule in physiological oxidative stress (2018) (2)
A tribute to Lars Ernster (1999) (2)
Induction of mitochondrial (MT) DNA mutations in human fibroblasts by in-vitro ultraviolet a (UVA) irradiation (1998) (2)
Mechanism of arachidonic acid stimulated singlet oxygen formation by prostaglandin endo per oxide synthase (1984) (2)
Highlight: Molecular and Cellular Mechanisms of Memory (2009) (2)
Induction of mouse embryonal carcinoma cell differentiation and activation of the retinoic acid receptor beta 2 promoter by 1,25-dihydroxyvitamin D3. (1996) (2)
Lycopene and β-Carotene (1998) (2)
Selenoproteins and thioredoxin (2002) (1)
Sensitized Chemiluminescence and Fluorescence Methods in Studies of Oxidative Stress (1999) (1)
Carotenoids: modes of action and bioavailability of lycopene in the human. (1999) (1)
Two centuries since discovery of dawn-of-life molecule (2018) (1)
Activation of JNK and P38 but not ERK map kinases in human skin cells by 5-aminolevulinate PDT, UVA and singlet oxygen (1998) (1)
Book Review: Biological Oxidation of Nitrogen in Organic Molecules Chemistry, Toxicology and Pharmacology. Edited by J. W. Gorrod and L. A. Damani (1986) (1)
Dietary Flavanols: Biochemical Basis of Short‐Term and Longer‐Term Vascular Responses (2009) (1)
6 – A New Function for Selenoproteins: Peroxynitrite Reduction (1999) (1)
Strategies for Controlling Oxidative Stress: Protection Against Peroxynitrite and Hydroperoxides by Selenoproteins and Selenoorganic Compounds (2002) (1)
Total Antioxidant Capacity : Appraisal of a Concept 1 , 2 (2007) (1)
Oxidative Stress: Impact in Neuroscience Research (2013) (1)
Effects of singlet oxygen on the biological activity of DNA and its involvement in single strand-break formation. (1988) (1)
Plasma longitudinal changes of carotenoids and malondialdehyde in stroke patients: relationship to outcome (2001) (1)
Free radicals in biotechnology and medicine (1990) (1)
[Oxidation in glutathione and NADP system and GSSG liberation in extracellular spaces using hydroperoxide in the hemoglobin-free perfused rat liver]. (1972) (1)
Editorial Note (1987) (1)
A 47-amino-acid fragment of SV40 T antigen represses transcription from human GSTalpha promoters. (1998) (1)
Cocoa flavanols lower arginase activity in human endothelial cells in vitro (2007) (1)
Lipid Peroxidation and Its Measurement (1987) (1)
Sulfur and Selenium: The Role of Oxidation State in Protein Structure and Function (2004) (1)
Memories of a Senior Scientist Biological Redox Systems and Oxidative Stress (2007) (1)
[Glutathione content of the lens in various forms of cataract]. (1982) (1)
Excited oxygen species, pyridine nucleotides and calcium transport (1984) (1)
Carotenoids: Looking Forward (2004) (1)
A New Function for Selenoproteins (1999) (1)
Special issue "polyphenols and health". (2014) (1)
Extreme longevity: the role of antioxidant enzymes, vitamins, and micronutrients. (2001) (1)
ITS INVOLVEMENT IN SINGLE STRAND-BREAK FORMATION (1988) (0)
IN STUDIES OF 02 GRADIENTS DURING HYPOXIA IN LIVER (1978) (0)
Studies on the redox state of cytochrome oxidase in intact rat skeletal muscle (perfused hindlimb) by Dual-Wavelength Spectrophotometry (1982) (0)
O27. Dietary flavanols and vascular responses: Attenuation of NADPH oxidase and preservation of NO (2008) (0)
[Mechanism of liver damage. Pathogenesis of primary hemochromatosis and auxiliary liver transplantation]. (1995) (0)
Hypolipidemic agents : Edited by D. Kritchevsky Springer-Verlag, Berlin, Heidelberg, New York, 1975 xvi + 490 pages. Cloth DM 178., $ 73.00 (1977) (0)
Singlet oxygen induced mutagenicity in epissomal sv-40 derived shuttle vector (1989) (0)
Genetic Polymorphisms in Selenoprotein Genes: Functionality and Disease Risk (2015) (0)
Two centuries since discovery of dawn-of-life molecule (2018) (0)
Triplet Carbonyl Species Generated from 3-Hidroxymethyl-3,4,4-trimethyl-1,2-dioxetane (HTMD) Induce on cis,trans Isomerization of Carotenóids (1993) (0)
Mercaptan derivatives, processes for their preparation and pharmaceutical compositions containing them (1984) (0)
Activation of Gene Expression of Collagenase and ICAM-1 by UVA Radiation and by Exposure to Singlet Oxygen (1998) (0)
Book Reviews : New Comprehensive Biochemistry Volume 28: Free Radical Damage and its Control General Editors: A.Neuberger & L.L.M. Van Deenen Edited by C.A. Rice-Evans & R.H. Burdon Elsevier, The Netherlands, 1994, pp. 392. US $ 177.25 (1995) (0)
Glutathione Conjugate Transport in Hepatic Elimination of Electrophiles (1989) (0)
Quinone Redox Cycling and the Protective Effect of DT Diaphorase (1990) (0)
Menadione) in Perfused Rat Liver (1989) (0)
Contents Index (2003) (0)
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents (2020) (0)
Activation of EGF receptor-dependent signaling pathways by alkylating and redox-cycling quinones (2002) (0)
Highlight: Redox signaling – mechanisms and biological impact (2006) (0)
60 The metabolism of 4-methoxy-β-chloro styrene by liver microsomal monooxygenases (1978) (0)
SINGLET OXYGEN- AND UVA-INDUCED GENE EXPRESSION (1996) (0)
Proceedings: Monooxygenase activity and nicotinamide nucleotide systems in perfused rat liver. (1975) (0)
Editor's Note (2006) (0)
P071. NO-mediated inhibition of androgen receptor activity: Possible implications for prostate cancer progression (2006) (0)
Editorial Year-end Note (2008) (0)
ROLE OF GLUTATHIONE AND NAD(P)H:QUINONE OXIDOREDUCTASE (DT-DIAPHORASE) IN DETERMINING LOW-LEVEL CHEMILUMINESCENCE DURING REDOX CYCLING OF MENADIONE (1984) (0)
Antioxidant Systems in Biological Material (1988) (0)
Oxygen Free Radicals and Tissue Damage. Ciba Foundation Symposium 65 (new series). Excerpta Medica, Amsterdam 1979. VIII, 381 S., geb. $ 52.75 (1980) (0)
Proceedings of the 1st International Conference of Collaborative Research Center 974: Liver Damage and Regeneration (2014) (0)
Physiological redox balance: Oxidative eustress (2022) (0)
Targets of chemotherapy at the molecular level (1984) (0)
Se Compounds with Specific Functions (2015) (0)
Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia (2005) (0)
Dietary selenium affects intestinal development of Eimeria papillata in mice (2013) (0)
Ozone in Arteriosclerotic Plaques: Searching for the “Smoking Gun” (2004) (0)
Se Compounds as a Source for Selenoprotein Biosynthesis (2015) (0)
Highlight: GBM Meeting ‘Molecular Life Sciences 2011’ (2012) (0)
Contents Vol. 18, 2004 (2004) (0)
Editorial (2009) (0)
Farewell to Hans Fritz, Executive Editor (2008) (0)
Decreased expression of the gluntatMoee S-tramsferases genes in humairn remal cell carcinoma (2005) (0)
Highlight issue: enzymology of drug metabolism and toxicology. (2007) (0)
APPLICATION TO OXYGEN-DEPENDENT PARAMETERS (1978) (0)
Role of Key Defense Systems in Target Organ Toxicity (2019) (0)
Immunopharmacology of free radical species: edited by David Blake and Paul G Winyard. Academic Press, 1995, 301 pages. $45.00 hardcover (ISBN 0-12-103520-4) (1995) (0)
Biomembranes : Pt. F,Vol. 55: Bioenergetics - Oxidative Phosphorylation (1979) (0)
Oxidative stress and redox signalling: an update (2011) (0)
Formation of reactive oxygen species: Introductory overview (1988) (0)
Organ-photometric analysis of metabolic functions in subcellular compartments (1982) (0)
BILIARY TAUROCHOLATE RELEASE DURING REDOX CYCLING IN PERFUSED RAT LIVER (1984) (0)
Preface (2014) (0)
Tetramethyl-ortho-quinodimethane, First Member of a Family of Custom- Tailored Cheletropic Spin Traps for Nitric Oxide. (1992) (0)
COMPARATIVE TOXICOLOGY OF OZONE AND LUNG t-BUTYL HYDROPEROXIDE ON ISOLATED RAT (1989) (0)
Editor's Note (2008) (0)
Hydroperoxide metabolism in hemoglobin-free perfused rat liver. (1973) (0)
Mercaptanderivater, process for their preparation and pharmaceutical compositions containing same (1985) (0)
Glimpse of metabolic coordination (1983) (0)
Decrease of flux through pyruvate dehydrogenase and branched-chain 2-oxo-acid dehydrogenase by nitrofurantoin in perfused rat liver. (1983) (0)
Book reviews (2005) (0)
Plasma vitamin E levels are lowered in patients with severe viral hepatitis (1995) (0)
Ethane production of isolated perfused rat liver (0)
ORGAN SPECTROPHOTOMETRY OF CYTOCHROME P-450 AND OF CATALASE LIGAND COMPLEXES IN INTACT PERFUSED LIVER (1978) (0)
Biliary Taurocholate Excretion During the Metabolism of 2-Methyl-1, 4-Naphthoquinone (Menadione) in Perfused Rat Liver (1989) (0)
Book Review: Vitamin C: Its Chemistry and Biochemistry. By M. B. Davies, J. Austin, and D. A. Partridge (1992) (0)
Selenium Mediates a Switch in Macrophage Polarization (2015) (0)
Tribute to Professor Minor J. Coon. (2011) (0)
Highlight: 'regenerative hepatology'. (2009) (0)
Towards identifying novel anti-Eimeria agents: trace elements, vitamins, and plant-based natural products (2014) (0)
Mechanisms of cell injury: Implications for human health. Dahlem Conference: Life Sciences Research Report 37, B. A. Fowler (ed.). John Wiley and Sons: Chichester, New York, Brisbane, Toronto, Singapore, 466 pages, £50·00 (1987). ISBN 0 471 91629 3 (1988) (0)
Formation of Singlet Oxygen in the Deoxygenation of Heteroarene N‐ Oxides by Dimethyldioxirane. (1996) (0)
L-arginine availability contributes to expression pattern of proinflammatory genes (2006) (0)
NO-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression (2006) (0)
P91. Modulation of NO metabolism in vascular endothelial cells by oxidized LDL (2008) (0)
List of Participants (2012) (0)
Nutrition and Disease Long-Term Ingestion of High Flavanol Cocoa Provides Photoprotection against UV-Induced Erythema and Improves Skin Condition in Women 1 (2006) (0)
LOW-LEVEL CHEMILUMINESCENCE, ALKANE PRODUCTION AND GLUTATHIONE DEPLETION IN ISOLATED HEPATOCYTES CAUSED BY A DIFFUSIBLE PRODUCT OF LIPID PEROXIDATION, 4-HYDROXYNONENAL (1984) (0)
LESTER PACKER: ON HIS LIFE AND HIS LEGACY. (2018) (0)
Effects of4-hydroxynonenal onisolated hepatocytes Studies onchemiluminescence response, alkane production andglutathione status (1983) (0)
Redox Cycling and the Toxicity of Selenium Compounds: A Historical View (2015) (0)
Antioxidant and radical scavenging abilities of ebselen and relation to vitamin E (1990) (0)
To our authors, readers and subscribers ‘Just Accepted’ feature at http://www.atypon-link.com/WDG/loi/bchm (2007) (0)
FOOD-CHAIN SELENIUM AND HUMAN HEALTH: EMPHASIS ON INTAKE (2008) (0)
Editors' Note (2003) (0)
Editors' Note (2008) (0)
[Redox status of the mitochondrial respiratory chain in the perfused rat liver]. (1969) (0)
Issue Information (2021) (0)
Selenite in Cancer Therapy (2015) (0)
Mechanisms involved in down-regulation of glutathione s-transferases alpha in human cancer cells (2007) (0)
Medical Applications of Antioxidants: An Update of Current Problems (1993) (0)
OxLDL signaling in endothelial cells and counteracting effects of (-)-epicatechin (2006) (0)
Subject Index Vol. 18, 2004 (2004) (0)
Cocoa polyphenols and inflammatory mediators 1 – 4 (2004) (0)
Differentiation Expression during Enterocytic Cell Induction of Glutathione Peroxidase 4 Gene Regulation (2011) (0)
Induction of the human heme oxygenase-1 (HO-1) gene by ultraviolet a radiation (UVAR) and osmotic stress (1998) (0)
Selenoprotein P protects human astrocytes from oxidative cell death (2006) (0)
Oxidative Stress in Skeletal Muscle. Edited by A. Z. Reznick, L. Packer, C. K. Sen, J. O. Holloszy and M. J. Jackson. Birkhaüser Verlag, Basel, Boston, Berlin, 346 pages, hardback. ISBN 3‐7643‐5820‐3 (1998) (1999) (0)
Issue Information (2020) (0)
Selenium-containing compounds inactivate peroxynitrite and protect DNA from single-strand breaks more effectively than their sulfur analogs (1996) (0)
Glutathione peroxidases as peroxynitrite reductases (1998) (0)
Concepts of membranes in regulation and excitation : Edited by Rocha e Silva and G. Suarez-Kurtz Raven Press, Publishers, New York 1975 xi + 226 pages. Dfl. 45.00, $ 18.75 (1977) (0)
Schrödingers Koffer (2020) (0)
SELENIUM AND THE PROTECTION AGAINST PEROXYNITRITE (2002) (0)
Role of specific protein S-thiolation under oxidative stress (1990) (0)
(-)-Epicatechin Is Taken up by Cells and Protects against Peroxynitrite-Induced Oxidation and Nitration. (2002) (0)
Author index and subject index (1976) (0)
Thiol enzymes and proteins (2002) (0)
Molecular mechanisms underlying disruption of gap junctional intercellular communication in tumor cells (2005) (0)
Chocolate: Modern Science Investigates an Ancient Medicine Reactions of Peroxynitrite with Cocoa Procyanidin Oligomers (2000) (0)
Oxidative Stress : Antioxidants in Degenerative Neurologic and Ophthalmologic Diseases (2006) (0)
In memoriam: Emeritus Professor Robin L. Willson (2022) (0)
Protective function of Selenoprotein P in human astrocytes (2005) (0)
Using inhibitors of gamma-GT for the treatment of chronic degenerativerkrankungen (2002) (0)
Use of isolated liver perfusion in metabolic studies: ground-laying work in experimental hepatology. (2011) (0)
Thiol Redox Regulation : A Brief Historical Overview (2021) (0)
Positive and Negative Regulatory Regions in Promoters of Human GlutathioneTransferase Alpha Genes (2009) (0)
Singlet molecular oxygen induced changes in DNA: Single-strand breaks, loss of biological activity and mutagenicity (1990) (0)
Reactive oxygen species-dependent transdifferentiation of skin fibroblasts enhances invasive capacity of tumor cells (2005) (0)

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