Coen Hemker
#159,696
Most Influential Person Now
Dutch university teacher
Coen Hemker's AcademicInfluence.com Rankings
Coen Hemkerbiology Degrees
Biology
#14850
World Rank
#18715
Historical Rank
Biochemistry
#2609
World Rank
#2783
Historical Rank
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Chemistry Biology
Coen Hemker's Degrees
- PhD Biochemistry Leiden University
- Masters Chemistry Leiden University
Why Is Coen Hemker Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hendrik Coenraad "Coen" Hemker is a Dutch biochemist and academic administrator. He was one of the founders of Maastricht University and was its rector magnificus from 1982 to 1984. He was a professor of biochemistry from 1975 until 1999. In his research he has mainly studied thrombosis and hemostasis.
Coen Hemker's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B (2005) (314)
- The Thrombogram: Monitoring Thrombin Generation in Platelet Rich Plasma (2000) (298)
- Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article (2013) (63)
- Fixed dosage of low‐molecular‐weight heparins causes large individual variation in coagulability, only partly correlated to body weight (2006) (63)
- Thrombin-generating capacity in patients with von Willebrand’s disease (2007) (58)
- New approaches for measuring coagulation (2006) (51)
- Fibrin polymerization is crucial for thrombin generation in platelet‐rich plasma in a VWF–GPIb‐dependent process, defective in Bernard–Soulier syndrome (2004) (50)
- The balance of pro‐ and anticoagulant processes underlying thrombin generation (2015) (50)
- Is there value in kinetic modeling of thrombin generation? No (unless…) (2012) (48)
- The Effect of DDAVP Infusion on Thrombin Generation in Platelet-rich Plasma of von Willebrand Type 1 and in Mild Haemophilia A Patients (2000) (47)
- Recollections on thrombin generation (2008) (46)
- The Influence of Oral Contraceptives on the Time-Integral of Thrombin Generation (Thrombin Potential) (1993) (44)
- Measurement of thrombin generation intra-operatively and its association with bleeding tendency after cardiac surgery. (2014) (42)
- A century of heparin: past, present and future (2016) (42)
- Asthma is associated with enhanced thrombin formation and impaired fibrinolysis (2016) (40)
- The paradoxical stimulation by a reversible thrombin inhibitor of thrombin generation in plasma measured with thrombinography is caused by α2‐macroglobulin‐thrombin (2010) (39)
- Thrombin-dependent Incorporation of von Willebrand Factor into a Fibrin Network* (2014) (39)
- The technique of measuring thrombin generation with fluorogenic substrates: 3. The effects of sample dilution (2008) (35)
- Thrombin-induced Hyperactivity of Platelets of Young Stroke Patients (2002) (33)
- Differences in the mechanism of blood clot formation and nanostructure in infants and children compared with adults. (2015) (33)
- Thrombin generation is extremely sensitive to preheating conditions (2011) (32)
- Increased thrombin generation among postmenopausal women using hormone therapy: importance of the route of estrogen administration and progestogens (2011) (31)
- Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system (2007) (31)
- Inhibition of phospholipid and platelet‐dependent prothrombinase activity in the plasma of patients with lupus anticoagulants (1989) (30)
- Prothrombotic State in Asthma Is Related to Increased Levels of Inflammatory Cytokines, IL-6 and TNFα, in Peripheral Blood (2017) (28)
- Factor Xa Cleavage of Tissue Factor Pathway Inhibitor Is Associated with Loss of Anticoagulant Activity (1998) (28)
- Nomenclature of Quantities and Units in Thrombosis and Haemostasis (Recommendation 1993) (1994) (26)
- Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A (2011) (25)
- Laboratory assessment of antithrombotic therapy: what tests and if so why? (1997) (24)
- Increased blood levels of cellular fibronectin in asthma: Relation to the asthma severity, inflammation, and prothrombotic blood alterations. (2018) (19)
- A new regulatory function of activated factor V: inhibition of the activation by tissue factor/factor VII(a) of factor X (2013) (14)
- Caution in the interpretation of continuous thrombin generation assays: a rebuttal (2007) (13)
- Age-dependency of thrombin generation (2006) (13)
- Impaired fibrinolysis and lower levels of plasma α2-macroglobulin are associated with an increased risk of severe asthma exacerbations (2017) (11)
- Thrombin generation in whole blood (2008) (11)
- The contribution of α2‐macroglobulin thrombin to the endogenous thrombin potential (2007) (9)
- The contribution of alpha(2)-macroglobulin thrombin to the endogenous thrombin potential. (2007) (9)
- The Elevated Risk for Venous Thrombosis in Persons with Hyperhomocysteinemia Is not Reflected by the Endogenous Thrombin Potential (1999) (9)
- Monitoring new oral antithrombotics: what we should know before we can decide (2010) (8)
- The initiation phase – A review of old (clotting-) times (2007) (8)
- Thrombin Generation in Zebrafish Blood (2016) (7)
- Procoagulant effect of vitamin K antagonists? (2011) (6)
- An Ionic Contrast Agent Inhibits Platelet-dependent Thrombin Generation and Boosts the Effect of Abciximab (2001) (6)
- Exploring the limits of modelling thrombus formation: Comment on "Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones" by A.V. Belyaev et al. (2018) (5)
- The love of the artist for his model of thrombin generation (2004) (3)
- Mathematical and biological models of blood coagulation. A rebuttal (2006) (3)
- Alpha-2-Macroglobulin Is a Major Determinant Of a Lower Thrombin Generation In Infants and Children Compared To Adults (2013) (3)
- THE EFFECT OF DIRECT THROMBIN INHIBITORS (DTIS) IN CLOTTING PLASMA (2007) (3)
- Recombinant Porcine Factor VIII Corrects Thrombin Generation and Improves Clot Structure In Vitro in Plasma Containing Anti-Factor VIII Inhibitory Antibodies (2011) (2)
- Determination of heparin in blood (1990) (2)
- The technique of measuring thrombin generation with fluorescent substrates: 4. The H-transform, a mathematical procedure to obtain thrombin concentrations without external calibration (2009) (2)
- Aprotinin and hemostasis in cardiopulmonary bypass (1995) (1)
- Faculty Opinions recommendation of Occult cancer screening in patients with venous thromboembolism: guidance from the SSC of the ISTH. (2018) (1)
- α2Macroglobulin Fails To Compensate For Decreased Thrombin Decay In Severe Antithrombin Deficiency In Liver Cirrhosis Patients (2013) (1)
- Effect of five therapeutic strategies on the coagulation defect induced by the thrombomodulin c.1611C>A mutation (2015) (1)
- Advantages, Pitfalls, and Snags with Chromogenic Substrates (1980) (1)
- The mode of action of dermatan sulphate in plasma (1990) (1)
- Faculty Opinions recommendation of Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram: A Nordic study. (2019) (1)
- Rebalanced Thrombin Generation in Liver Cirrhosis Calls for Tailored Transfusion Protocols (2015) (1)
- Measuring the conversion of a chromogenic substrate (1983) (1)
- Fibrinogen Attentuates Thrombin Decay In a Concentration-Dependent Manner (2013) (1)
- Automotrice combine with a cutting tool in two parts. (1988) (0)
- Umbilical Vein Endothelial Cells Expression of Adhesion Molecules by Human Factor Xa Induces Cytokine Production and (1998) (0)
- In memoriam Paul Paulssen (1984) (0)
- Faculty Opinions recommendation of Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis. (2017) (0)
- Reply to Rebuttal: On the Role of EPR-1 or an EPR-1-like Molecule in Regulating Factor Xa Incorporation into Platelet Prothrombinase (2001) (0)
- Simultaneous Measurement of Thrombin Generation and Fibrin Formation in Whole Blood Applying Continuous Flow Is Predictive for the Amount of Blood Loss during/after Cardiothoracic Surgery (2014) (0)
- Thrombin-Dependent Incorporation of Von Willebrand Factor into a Fibrin Network (2014) (0)
- Low molecular weight heparin (LMWH) treatment in ulcerative colitis (1998) (0)
- Faculty Opinions recommendation of Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release. (2017) (0)
- Willebrand Factor into a Fibrin Network Thrombin-dependent Incorporation of von Protein Structure and Folding : (2014) (0)
- Wf propeptide containing pharmaceutical preparation (1998) (0)
- The mode of action of heparinin plasma (1988) (0)
- Elevated Fibrinogen Levels in Patients Treated with Vitamin K Antagonists Attenuate the Inactivation of Thrombin (2016) (0)
- C0305: A2Macroglobulin does Not Compensate for Antithrombin Deficiency in Severe Liver Cirrhosis (2014) (0)
- Restoration of Procoagulant Factor Levels after Cardiac Surgery Causes Thrombin Generation to Rise to Thrombotic Levels (2015) (0)
- In Memoriam Hymie L. Nossel (1984) (0)
- Prothrombotic State in Asthma Is Related to Increased Levels of Inflammatory Cytokines, IL-6 and TNFα, in Peripheral Blood (2017) (0)
- Antithrombotic drugs. (2014) (0)
- Impaired fibrinolysis and lower levels of plasma α2-macroglobulin are associated with an increased risk of severe asthma exacerbations (2017) (0)
- inhibition ofhumanFactor XIaby antithrombin IIIisdependent on theheparin type (1988) (0)
- Development of a Neural Network to Predict Thrombosis in the Antiphospholipid Syndrome with an Accuracy of 87% (2018) (0)
- Faculty Opinions recommendation of A systematic review and Bayesian network meta-analysis of risk of intracranial hemorrhage with direct oral anticoagulants. (2019) (0)
- Faculty Opinions recommendation of Reduced-dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta-analysis. (2018) (0)
- Kinetics oftheinhibition ofhumanfactor Xabyfull-length andtruncated recombinant tissue factor pathway inhibitor (1994) (0)
- Fixed Doses of Anticoagulants Cause Wide Variation of Thrombin Generation (2016) (0)
- The clinical usefulness of measuring thrombin generation (2023) (0)
- Thrombin Generation in Zebrafish (2014) (0)
- A method for detecting the endogenous thrombin-potentials and thrombin substrates procedure for use in these (1996) (0)
- Faculty Opinions recommendation of Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: A Population-Based Cohort Study. (2019) (0)
- Th et echnique of measuring thrombin generatio nw it hf luorescent substrates :4 .T he H-transform ,a mathematical procedur et o obtain thrombi nc oncentrations without external calibration (2009) (0)
- Self-propelled forage harvester convertable to function as a combine harvester (1986) (0)
- Self-propelled combine harvester comprising a cutting mechanism divided into two (1988) (0)
- [Thrombinoscopy: measuring thrombin generation]. (2011) (0)
- A NEW CASE OF A CONGENITAL COMBINED HYPO-DYSFIBRINOGENEMIA? (1987) (0)
- Self-propelled combine harvester, with a two-piece cutting device (1988) (0)
- Determinations that can be carried out with chromogenic substrates (1983) (0)
- Self-propelled combine harvester with a two-part cutting mechanism (1988) (0)
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What Schools Are Affiliated With Coen Hemker?
Coen Hemker is affiliated with the following schools:
