Hendrik Streeck
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German virologist
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Hendrik Streeckbiology Degrees
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Biology
Hendrik Streeck's Degrees
- Doctorate Medicine University of Bonn
- PhD Virology University of Bonn
Why Is Hendrik Streeck Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hendrik Streeck is a German researcher of human immunodeficiency virus, epidemiologist and clinical trialist. He is professor of virology and the director of the Institute of Virology and HIV Research at the University Bonn.
Hendrik Streeck's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation (2010) (1129)
- Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1 (2009) (526)
- Differential natural killer cell–mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes (2007) (464)
- Expansion of HIV-specific T follicular helper cells in chronic HIV infection. (2012) (408)
- A Functional Role for Antibodies in Tuberculosis (2016) (387)
- A Blueprint for HIV Vaccine Discovery. (2012) (372)
- Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection (2012) (350)
- Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines (2014) (349)
- HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1 (2006) (345)
- Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. (2005) (339)
- Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. (2013) (291)
- Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology (2015) (286)
- Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells (2008) (266)
- Infection fatality rate of SARS-CoV-2 infection in a German community with a super-spreading event (2020) (263)
- MyD88-Dependent Immune Activation Mediated by Human Immunodeficiency Virus Type 1-Encoded Toll-Like Receptor Ligands (2007) (260)
- HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome (2012) (247)
- Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells (2009) (223)
- Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence (2012) (210)
- Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality (2020) (210)
- Sex differences in vaccine-induced humoral immunity (2018) (208)
- Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection (2008) (202)
- HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function (2010) (187)
- Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. (2007) (159)
- Rapid point-of-care testing for SARS-CoV-2 in a community screening setting shows low sensitivity (2020) (159)
- Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany (2020) (155)
- Recognition of a Defined Region within p24 Gag by CD8+ T Cells during Primary Human Immunodeficiency Virus Type 1 Infection in Individuals Expressing Protective HLA Class I Alleles (2007) (145)
- Protective HLA Class I Alleles That Restrict Acute-Phase CD8+ T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1 (2008) (141)
- Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection (2010) (140)
- Cytolytic CD4+ T cells in viral immunity (2010) (134)
- The role of IFN-γ Elispot assay in HIV vaccine research (2009) (126)
- Immune-driven recombination and loss of control after HIV superinfection (2008) (125)
- T cell immunity in acute HIV-1 infection. (2010) (114)
- A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation☆ (2019) (112)
- Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination (2016) (109)
- Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells1 (2007) (109)
- Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands (2008) (102)
- HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome (2011) (100)
- Harnessing CD4+ T cell responses in HIV vaccine development (2013) (98)
- Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions. (2016) (96)
- Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control (2013) (93)
- Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. (2006) (91)
- Fc Receptor-Mediated Phagocytosis in Tissues as a Potent Mechanism for Preventive and Therapeutic HIV Vaccine Strategies (2016) (79)
- Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia (2015) (73)
- Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue. (2012) (68)
- Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement (2018) (67)
- Lack of Protection following Passive Transfer of Polyclonal Highly Functional Low-Dose Non-Neutralizing Antibodies (2014) (64)
- SARS-CoV-2 in Environmental Samples of Quarantined Households (2020) (62)
- Correlation between a quantitative anti‐SARS‐CoV‐2 IgG ELISA and neutralization activity (2021) (60)
- CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity (2016) (58)
- IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection (2015) (57)
- Effect of HIV infection and antiretroviral therapy on immune cellular functions. (2019) (56)
- Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16 (2016) (51)
- Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion (2016) (49)
- Induction of Gag-Specific CD4 T Cell Responses during Acute HIV Infection Is Associated with Improved Viral Control (2014) (46)
- Ad hoc laboratory-based surveillance of SARS-CoV-2 by real-time RT-PCR using minipools of RNA prepared from routine respiratory samples (2020) (46)
- Independent evolution of Fc‐ and Fab‐mediated HIV‐1‐specific antiviral antibody activity following acute infection (2014) (45)
- Immunodominant HIV-1 Cd4+ T Cell Epitopes in Chronic Untreated Clade C HIV-1 Infection (2009) (42)
- Rapid ex vivo isolation and long-term culture of human Th17 cells. (2008) (41)
- Emerging concepts on T follicular helper cell dynamics in HIV infection. (2014) (41)
- Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection (2006) (37)
- Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity (2020) (36)
- Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccination (2018) (36)
- CD4+ CD25+ Regulatory T Cells Impair HIV-1-Specific CD4 T Cell Responses by Upregulating Interleukin-10 Production in Monocytes (2012) (36)
- Memory B cells targeting SARS-CoV-2 spike protein and their dependence on CD4+ T cell help (2021) (35)
- Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors (2017) (33)
- Enhancing the Quality of Antibodies to HIV-1 Envelope by GagPol-Specific Th Cells (2015) (33)
- Epithelial adhesion molecules can inhibit HIV-1-specific CD8⁺ T-cell functions. (2011) (32)
- Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8+ T Cells in Human Immunodeficiency Virus Type 1 Infection (2008) (32)
- Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals (2020) (31)
- Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections (2020) (31)
- Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome (2014) (31)
- Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection (2017) (30)
- Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection (2016) (29)
- Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers (2017) (29)
- Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease (2018) (28)
- Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size. (2018) (27)
- How a single patient influenced HIV research--15-year follow-up. (2014) (26)
- TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections. (2016) (25)
- Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 (2022) (24)
- Barriers to HIV Cure (2016) (23)
- Exploiting glycan topography for computational design of Env glycoprotein antigenicity (2018) (20)
- Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection. (2011) (20)
- Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection (2017) (19)
- Induction of Strong HIV-1–Specific CD4+ T-Cell Responses Using an HIV-1 gp120/NefTat Vaccine Adjuvanted With AS02A in Antiretroviral-Treated HIV-1–Infected Individuals (2012) (19)
- Rapid loss of dendritic cell and monocyte responses to TLR ligands following venipuncture. (2008) (18)
- Mining for humoral correlates of HIV control and latent reservoir size (2020) (15)
- Characteristic Temporary Loss of Taste and Olfactory Senses in SARS-CoV-2-positive-Individuals with Mild Symptoms (2020) (15)
- Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection (2013) (15)
- Human Immunodeficiency Virus Type 1-Specific CD 8 T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD 4 T Cells † (2009) (13)
- Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression. (2007) (13)
- Pre-exposure prophylaxis failure with tenofovir disoproxil. (2017) (13)
- Predicting the Immunogenicity of T cell epitopes: From HIV to SARS-CoV-2 (2020) (12)
- Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination (2016) (12)
- HIV & Infections (2009) (10)
- Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes (2020) (10)
- AIDS virus seeks refuge in B cell follicles (2015) (9)
- Learning from HIV-1 to predict the immunogenicity of T cell epitopes in SARS-CoV-2 (2021) (9)
- IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees (2020) (9)
- Expansion of Stem Cell-Like CD4+ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression (2019) (8)
- P09-20 LB. Ultra-deep sequencing of full-length HIV-1 genomes identifies rapid viral evolution during acute infection (2009) (8)
- Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans (2018) (7)
- Low-threshold SARS-CoV-2 testing facility for hospital staff: Prevention of COVID-19 outbreaks? (2020) (7)
- Persistent Maintenance of Intermediate Memory B Cells Following SARS-CoV-2 Infection and Vaccination Recall Response (2022) (7)
- Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology (2020) (7)
- Review of tipranavir in the treatment of drug-resistant HIV (2007) (7)
- Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection. (2017) (7)
- Designing optimal HIV-vaccine T-cell responses (2016) (7)
- Case Report: Infection With SARS-CoV-2 in the Presence of High Levels of Vaccine-Induced Neutralizing Antibody Responses (2021) (6)
- Protein-based, but not viral vector alone, HIV vaccine boosting drives an IgG1-biased polyfunctional humoral immune response. (2020) (6)
- P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity (2009) (6)
- Preexposure prophylaxis failure with tenofovir disoproxil. (2017) (5)
- T-cell responses in primary HIV-1 infection (2008) (5)
- Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses. (2012) (5)
- Serological Markers of SARS-CoV-2 Reinfection (2022) (5)
- Oral abstracts of the 21st International AIDS Conference 18–22 July 2016, Durban, South Africa (2016) (4)
- HIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019 (2022) (4)
- Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome (2009) (4)
- Subdominant Gag-specific anti-HIV efficacy in an HLA-B∗57-positive elite controller (2016) (4)
- Production of HIV-1 Env-Specific Antibodies Mediating Innate Immune Functions Depends on Cognate Interleukin-21- Secreting CD4+ T Cells (2021) (4)
- Rapid Uptake of Pre-Exposure Prophylaxis (PrEP) after Significant Price Reduction in Germany Highlights Importance of PrEP Accessibility. (2020) (4)
- Suppression of SARS‐CoV‐2 Replication with Stabilized and Click‐Chemistry Modified siRNAs (2022) (3)
- A Mycobacterium tuberculosis Specific IgG3 Signature of Recurrent Tuberculosis (2021) (3)
- Factors associated with testing for HIV and hepatitis C among behaviorally vulnerable men in Germany: a cross-sectional analysis upon enrollment into an observational cohort (2021) (2)
- P16-31. Skewed HIV-1-specific CD4+ Th2 helper cell contribution in progressive HIV-1 infection (2009) (2)
- Reduction of CD8 T Cell Functionality but Not Inhibitory Capacity by Integrase Inhibitors (2022) (2)
- Detectable SARS-CoV-2 RNAemia in Critically Ill Patients, but Not in Mild and Asymptomatic Infections (2021) (2)
- Analysis of the Dynamics, Outcome, and Prerequisites of the first German SARS-CoV-2 Superspreading Event (2021) (2)
- Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5 (2020) (2)
- Strategic anti-SARS-CoV-2 serology testing in a low prevalence pandemic: The COVID-19 Contact (CoCo) Study in health care professionals (2020) (2)
- B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV: Results from the HIV-HEART study. (2019) (2)
- Challenges in the treatment of HIV and HCV coinfection (2006) (2)
- SARS-CoV-2 humoral and cellular immunity following different combinations of vaccination and breakthrough infection (2023) (2)
- Dynamics, outcomes and prerequisites of the first SARS-CoV-2 superspreading event in Germany in February 2020: a cross-sectional epidemiological study (2022) (2)
- Analysis of fatality impact and seroprevalence surveys in a community sustaining a SARS-CoV-2 superspreading event (2022) (2)
- Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity (2022) (2)
- SARS-CoV-2 seroconversions and chains of infection in healthcare professionals in a German maximum care provider (The CoSHeP study) (2021) (1)
- Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection (2017) (1)
- Paradigm-violating HLA class II-restricted CD8 T cells exist in HIV infected individuals (VIR6P.1164) (2015) (1)
- Distinct HIV-Specific Antibody Fc-Profiles in RV144 and VAX003 Vaccinees (2013) (1)
- Emerging concepts on T FH cell dynamics in HIV infection (2014) (1)
- Dissecting drivers of immune activation in chronic HIV-1 infection (2022) (1)
- Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection (2013) (1)
- The effect of age on the magnitude and longevity of Th1‐directed CD4 T‐cell responses to SARS‐CoV‐2 (2022) (1)
- Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory Viruses (2022) (1)
- OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules (2009) (1)
- Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials (2021) (1)
- Transcriptomic profiles of NK cell function indicate impaired responsiveness in chronic HIV-1 infection and enhanced functional activity post-vaccination (2017) (0)
- HIV-Specific CD 8 Control through the Modulation of Responses Contribute to Durable Viral T Cell + CD 4 + HIV-1-Specific Interleukin-21 (2010) (0)
- Immunity against SARS-CoV-2 in the German population (2023) (0)
- P16-55 LB. The role of CD4+ CD25+ regulatory T cells in the control of IL-10 mediated T cell impairment in chronic HIV Infection (2009) (0)
- Kinetics of gp41-specific antibody titers and contribution of Fc mediated gp41 specific antibody responses following SHIV-SF162P3 challenge. (2014) (0)
- THE HIV VACCINE PROBLEM : WHY HAVE PAST APPROACHES TO DEVELOP AN HIV VACCINE FAILED ? (0)
- Reconstruction of the origin of the first major SARS-CoV-2 outbreak in Germany (2022) (0)
- Human Immunodeficiency Virus Type 1-Specific CD8 (cid:1) T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4 (cid:1) T Cells (cid:1) † (2009) (0)
- Preparing for future European efficacy trials of interventions to prevent HIV and other sexually transmitted infections: Lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with men (2023) (0)
- Sites and kinetics of HLA-associated immune escape in HIV-1 integrase (2009) (0)
- Longitudinal monitoring of mRNA-vaccine-induced immunity against SARS-CoV-2 (2023) (0)
- HIV-associated microbial translocation may affect cytokine production of CD56bright NK cells via stimulation of monocytes. (2022) (0)
- Regulatory T Cells Impair HIV-1-Specific CD 4 T Cell Responses by Upregulating Interleukin-10 Production in Monocytes (2012) (0)
- Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccination (2018) (0)
- Persistent Maintenance of Atypical Memory B Cells Following SARS-CoV-2 Infection and Vaccination Recall Response (2022) (0)
- Estimates of protection against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season - the IMMUNEBRIDGE project (2023) (0)
- Impaired humoral immunity to BQ.1.1 in convalescent and vaccinated patients (2023) (0)
- P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication (2009) (0)
- P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection (2009) (0)
- Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination (2023) (0)
- Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8 (cid:1) T Cells in Human Immunodeficiency Virus Type 1 Infection (cid:1) (2008) (0)
- The viral set point in primary HIV infection is associated with specific amino acids in position 97 of MHC class I (2012) (0)
- Cell-intrinsic TGF-β receptor signaling limits virus-specific CD4 T cell responses and prevents lethal pathology during chronic viral infection. (IRC2P.450) (2014) (0)
- HIV-specific cytolytic CD4 T-cell responses effectively control HIV infection in macrophages (2012) (0)
- MyD88-Dependent Immune Activation Mediated by Human Immunodeficiency Virus Type 1-Encoded Toll-Like Receptor Ligands (cid:1) (2007) (0)
- DIRECTORATE-GENERAL FOR HEALTH AND FOOD SAFETY Public health, country knowledge, crisis management Crisis management and preparedness in health (2019) (0)
- This information is current as HIV-1 Envelope by GagPol-Specific Th Cells Enhancing the Quality of Antibodies to Nabi (2015) (0)
- T Cell Function + HIV-Specific CD8 Control through the Modulation of Responses Contribute to Durable Viral T Cell + CD4 + HIV-1-Specific Interleukin-21 (2014) (0)
- Immune Responses to Viral Infection (2017) (0)
- Su.45. Longitudinal Evaluation of CTL Responses and HIV Sequence Evolution in Optimally Described HIV-1 CTL Epitopes During Acute/Early HIV-1 Infection (2008) (0)
- The viral set point in primary HIV infection is associated with specific amino acids in position 97 of MHC class I (2012) (0)
- Sex differences in vaccine-induced humoral immunity (2018) (0)
- Smoking is Associated with Reduced Frequency of SARS-CoV-2 Infection (2021) (0)
- Front Cover: Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity (ChemMedChem 5/2022) (2022) (0)
- HIV-specific cytolytic CD4 T-cell responses effectively control HIV infection in macrophages (2012) (0)
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Hendrik Streeck is affiliated with the following schools:
