Henning Beck‐nielsen
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Biology
Henning Beck‐nielsen's Degrees
- Bachelors Biology University of Copenhagen
- Masters Biotechnology University of Copenhagen
- PhD Neuroscience University of Copenhagen
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(Suggest an Edit or Addition)Henning Beck‐nielsen's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial (2009) (1317)
- Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis. (2007) (800)
- Heritability of Type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance – a population-based twin study (1999) (606)
- Mitochondrial Respiration Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes (2007) (535)
- Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. (1994) (375)
- Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins (1995) (363)
- Insulin Action and Age: European Group for the Study of Insulin Resistance (EGIR) (1996) (351)
- Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women. (2003) (350)
- Outcomes in Type 1 Diabetic Pregnancies: A nationwide, population-based study (2004) (349)
- Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus. (1992) (319)
- Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs (1997) (315)
- Randomised controlled trial of structured personal care of type 2 diabetes mellitus (2001) (311)
- Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins. (2004) (301)
- The LiP (Lifestyle in Pregnancy) Study (2011) (290)
- Genetic versus environmental aetiology of the metabolic syndrome among male and female twins (2001) (251)
- GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease? (2001) (247)
- Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial (2010) (231)
- Prevalence and Mortality of Acute Myocardial Infarction in Patients with Diabetes (1985) (231)
- Proteome Analysis Reveals Phosphorylation of ATP Synthase β-Subunit in Human Skeletal Muscle and Proteins with Potential Roles in Type 2 Diabetes* (2003) (224)
- Prevalence of micro- and macroalbuminuria, arterial hypertension, retinopathy and large vessel disease in European Type 2 (non-insulin-dependent) diabetic patients (1991) (219)
- The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c (2011) (219)
- Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance. (1999) (201)
- Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus. (1995) (201)
- Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism. (1987) (190)
- Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes. (2004) (182)
- Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects. (1980) (181)
- Lumbar vertebral body compressive strength evaluated by dual-energy X-ray absorptiometry, quantitative computed tomography, and ashing. (1999) (179)
- Insulin resistance, insulin response, and obesity as indicators of metabolic risk. (2007) (176)
- Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials (2010) (173)
- Gestational weight gain and pregnancy outcomes in 481 obese glucose-tolerant women. (2005) (172)
- Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes (2012) (172)
- Peri-Conceptional A1C and Risk of Serious Adverse Pregnancy Outcome in 933 Women With Type 1 Diabetes (2009) (170)
- Increased insulin receptors after exercise in patients with insulin-dependent diabetes mellitus. (1980) (169)
- Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome (2007) (168)
- Insulin resistance in growth hormone-deficient adults: defects in glucose utilization and glycogen synthase activity. (1996) (168)
- Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins. (2005) (167)
- Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women - results of the Danish Osteoporosis Prevention Study. (2000) (167)
- Total and regional fat distribution is strongly influenced by genetic factors in young and elderly twins. (2005) (166)
- The new Danish Twin Register: establishment and analysis of twinning rates. (1995) (165)
- Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. (2016) (164)
- Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)--evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins. (1996) (158)
- Clinical impact of mild carbohydrate intolerance in pregnancy: a study of 2904 nondiabetic Danish women with risk factors for gestational diabetes mellitus. (2001) (155)
- Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects. (2005) (154)
- The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. (2002) (154)
- Identification of the Oxidized Low-Density Lipoprotein Scavenger Receptor CD36 in Plasma: A Novel Marker of Insulin Resistance (2006) (152)
- Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene. (2005) (146)
- Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide. (1979) (141)
- Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol (2005) (140)
- Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study. (1990) (135)
- A cellular model system of differentiated human myotubes (2001) (135)
- Concentration‐response relationship in imipramine treatment of diabetic neuropathy symptoms (1990) (135)
- Age‐ and Gender‐Related Differences in Vertebral Bone Mass, Density, and Strength (1999) (132)
- Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts (2016) (132)
- Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes (2010) (130)
- Classification of Newly Diagnosed Diabetic Patients as Insulin-Requiring or Non—Insulin-Requiring Based on Clinical and Biochemical Variables (1988) (127)
- Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus. (1991) (124)
- Impaired Insulin-Stimulated Phosphorylation of Akt and AS160 in Skeletal Muscle of Women With Polycystic Ovary Syndrome Is Reversed by Pioglitazone Treatment (2008) (123)
- Increased glucose effectiveness in normoglycemic but insulin-resistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism. (1994) (123)
- Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes. (2003) (123)
- Reduced glycogen synthase activity in skeletal muscle from obese patients with and without Type 2 (non-insulin-dependent) diabetes mellitus (1991) (122)
- A flow cytometric method for characterization of circulating cell-derived microparticles in plasma (2014) (119)
- Hormone Replacement Therapy Dissociates Fat Mass and Bone Mass, and Tends to Reduce Weight Gain in Early Postmenopausal Women: A Randomized Controlled 5‐Year Clinical Trial of the Danish Osteoporosis Prevention Study (2003) (117)
- Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes. (1989) (117)
- Cross calibration of QDR-2000 and QDR-1000 dual-energy X-ray densitometers for bone mineral and soft-tissue measurements. (1995) (116)
- Maternal and perinatal outcomes in 143 Danish women with gestational diabetes mellitus and 143 controls with a similar risk profile (2000) (116)
- Left Ventricular Diastolic Function in Type 2 Diabetes Mellitus: Prevalence and Association With Myocardial and Vascular Disease (2010) (115)
- Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes. (2005) (115)
- Risk and mechanism of dexamethasone-induced deterioration of glucose tolerance in non-diabetic first-degree relatives of NIDDM patients (1997) (114)
- Screening for gestational diabetes mellitus by a model based on risk indicators: a prospective study. (2003) (113)
- Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training (2010) (113)
- Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway. (2005) (113)
- A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene. (2004) (113)
- Mitochondrial dysfunction in type 2 diabetes and obesity. (2008) (113)
- Outcomes in type 1 diabetic pregnancies: a nationwide, population-based study. (2005) (112)
- Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients (1996) (111)
- Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis. (2003) (110)
- Impact of hemodialysis on dual X-ray absorptiometry, bioelectrical impedance measurements, and anthropometry. (1996) (110)
- Impaired beta cell glucose sensitivity rather than inadequate compensation for insulin resistance is the dominant defect in glucose intolerance (2010) (106)
- Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes (2001) (105)
- Correlations between insulin sensitivity and bone mineral density in non‐diabetic men (2000) (102)
- Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique. (1996) (99)
- Triglyceride-induced diabetes associated with familial lipoprotein lipase deficiency. (1999) (99)
- Direct evidence of fiber type-dependent GLUT-4 expression in human skeletal muscle. (2000) (98)
- Cytokines and Bone Loss in a 5‐Year Longitudinal Study—Hormone Replacement Therapy Suppresses Serum Soluble Interleukin‐6 Receptor and Increases Interleukin‐1‐Receptor Antagonist: The Danish Osteoporosis Prevention Study (2000) (93)
- Decreased binding of insulin to its receptor in patients with congenital generalized lipodystrophy. (1977) (92)
- Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. (2005) (91)
- The Pathogenic Role of an Insulin-receptor Defect in Diabetes Mellitus of the Obese (1978) (89)
- Age-dependent impact of zygosity and birth weight on insulin secretion and insulin action in twins (2002) (89)
- Effect of Insulin Pump Treatment for One Year on Renal Function and Retinal Morphology in Patients with IDDM (1985) (88)
- Effect of insulin analogues on risk of severe hypoglycaemia in patients with type 1 diabetes prone to recurrent severe hypoglycaemia (HypoAna trial): a prospective, randomised, open-label, blinded-endpoint crossover trial. (2014) (88)
- Rosiglitazone RECORD study: glucose control outcomes at 18 months (2007) (88)
- First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes (2018) (87)
- AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes. (2004) (86)
- Microalbuminuria, Preeclampsia, and Preterm Delivery in Pregnant Women With Type 1 Diabetes (2009) (86)
- Rising prevalence of diabetes: evidence from a Danish pharmacoepidemiological database. (2003) (84)
- Variation in Absorption of NPH Insulin Due to Intramuscular Injection (1990) (83)
- Increased Risk of Type 2 Diabetes in Elderly Twins (2009) (83)
- Adverse pregnancy outcome in women with mild glucose intolerance: is there a clinically meaningful threshold value for glucose? (2008) (81)
- Effects of insulin on kidney function and sodium excretion in healthy subjects (1989) (80)
- The Danish Osteoporosis Prevention Study (DOPS): project design and inclusion of 2000 normal perimenopausal women. (1999) (80)
- Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects--experiences from relatives and twin studies. (2003) (80)
- Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both? (2003) (79)
- On the determination of basal glucose production rate in patients with Type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion (1990) (79)
- Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting. (2001) (78)
- Increased expression of 11β‐hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes (2005) (77)
- Expression of insulin regulatable glucose transporters in skeletal muscle from Type 2 (non-insulin-dependent) diabetic patients (1990) (77)
- Pioglitazone Enhances Mitochondrial Biogenesis and Ribosomal Protein Biosynthesis in Skeletal Muscle in Polycystic Ovary Syndrome (2008) (76)
- Mechanism of Action of Sulphonylureas with Special Reference to the Extrapancreatic Effect: An Overview (1988) (76)
- Left atrial volume index: relation to long-term clinical outcome in type 2 diabetes. (2013) (76)
- Assessment of hepatic insulin action in obese type 2 diabetic patients. (2001) (75)
- Free rather than total circulating insulin-like growth factor-I determines the feedback on growth hormone release in normal subjects. (2005) (75)
- Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population (2012) (74)
- OAS1 splice site polymorphism controlling antiviral enzyme activity influences susceptibility to type 1 diabetes. (2005) (74)
- Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity. (1983) (74)
- General characteristics of the insulin resistance syndrome: prevalence and heritability. European Group for the study of Insulin Resistance (EGIR). (1999) (73)
- The combined effect of triple therapy with rosiglitazone, metformin, and insulin aspart in type 2 diabetic patients. (2003) (73)
- Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: the RISC Study (2011) (73)
- Proliferation conditions for human satellite cells The fractional content of satellite cells (2001) (72)
- Insulin Resistance in Skeletal Muscles in Patients With NIDDM (1992) (72)
- Proposed diagnostic thresholds for gestational diabetes mellitus according to a 75‐g oral glucose tolerance test. Maternal and perinatal outcomes in 3260 Danish women (2003) (71)
- Incretin-Based Therapy and Risk of Acute Pancreatitis: A Nationwide Population-Based Case-Control Study (2015) (70)
- Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort. (2018) (69)
- A gene–gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin (2013) (69)
- Postpartum weight retention and breastfeeding among obese women from the randomized controlled Lifestyle in Pregnancy (LiP) trial (2014) (68)
- Normalization of the insulin sensitivity and the cellular insulin binding during treatment of obese diabetics for one year. (1979) (67)
- Efficacy and safety of the PPARγ partial agonist balaglitazone compared with pioglitazone and placebo: a phase III, randomized, parallel‐group study in patients with type 2 diabetes on stable insulin therapy (2011) (66)
- Insulin signalling in skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease (2002) (65)
- Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes (2006) (65)
- Diurnal variation in insulin binding to human monocytes. (1978) (65)
- Insulin Increases Renal Magnesium Excretion: A Possible Cause of Magnesium Depletion in Hyperinsulinaemic States (1995) (65)
- Plasma FGF21 displays a circadian rhythm during a 72‐h fast in healthy female volunteers (2011) (64)
- Increased insulin binding to adipocytes and monocytes and increased insulin sensitivity of glucose transport and metabolism in adipocytes from non-insulin-dependent diabetics after a low-fat/high-starch/high-fiber diet. (1983) (63)
- Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well‐being in patients with Type 1 diabetes mellitus (1999) (63)
- Effects of lifestyle intervention in pregnancy and anthropometrics at birth on offspring metabolic profile at 2.8 years: results from the Lifestyle in Pregnancy and Offspring (LiPO) study. (2015) (63)
- Vertebral bone density evaluated by dual-energy X-ray absorptiometry and quantitative computed tomography in vitro. (1998) (62)
- Automated detection of hypoglycemia-induced EEG changes recorded by subcutaneous electrodes in subjects with type 1 diabetes--the brain as a biosensor. (2010) (62)
- Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus. (2009) (61)
- Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period. (1994) (61)
- Improved In Vivo Insulin Effect During Continuous Subcutaneous Insulin Infusion in Patients with IDDM (1984) (60)
- Prednisone increases the number of insulin receptors on monocytes from normal subjects. (1980) (60)
- Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome. (2006) (60)
- The effect of metformin in overweight patients with type 1 diabetes and poor metabolic control. (2009) (59)
- Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity. (1980) (58)
- Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle (2010) (58)
- The effects of capillary dysfunction on oxygen and glucose extraction in diabetic neuropathy (2014) (57)
- The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes (2012) (57)
- Does zygosity influence the metabolic profile of twins? A population based cross sectional study (1999) (57)
- The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits (2015) (57)
- Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes (2008) (56)
- A novel oral dual amylin and calcitonin receptor agonist (KBP-042) exerts antiobesity and antidiabetic effects in rats. (2014) (55)
- β‐Cell function and glucose and lipid oxidation in Graves’ disease (1996) (55)
- Assessment of Glucose Turnover Rates in Euglycaemic Clamp Studies using Primed‐constant [3‐3H]‐glucose Infusion and Labelled or Unlabelled Glucose Infusates (1992) (55)
- Intramuscular Versus Subcutaneous Injection of Unmodified Insulin: Consequences for Blood Glucose Control in Patients with Type 1 Diabetes Mellitus (1990) (55)
- Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes (2014) (54)
- Concentration‐Response Relationship in Paroxetine Treatment of Diabetic Neuropathy Symptoms: A Patient‐Blinded Dose‐Escalation Study (1991) (54)
- Glucose transporter expression in human skeletal muscle fibers. (2000) (53)
- Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators of insulin resistance in type 2 diabetes? (2006) (53)
- Skeletal changes in osteoprotegerin and receptor activator of nuclear factor-kappab ligand mRNA levels in primary hyperparathyroidism: effect of parathyroidectomy and association with bone metabolism. (2004) (52)
- Insulin dependent diabetes mellitus in twins. (1996) (52)
- Insulin analogues and severe hypoglycaemia in type 1 diabetes. (2012) (52)
- Prostaglandin E2 receptor binding and action in human fat cells. (1984) (52)
- Decreased Activation of Skeletal Muscle Glycogen Synthase by Mixed-Meal Ingestion in NIDDM (1988) (51)
- The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes (2010) (50)
- Multiple defects of both hepatic and peripheral intracellular glucose processing contribute to the hyperglycaemia of NIDDM (1995) (48)
- Structured personal care of type 2 diabetes: a 19 year follow-up of the study Diabetes Care in General Practice (DCGP) (2013) (47)
- Effect of moderate improvement in metabolic control on magnesium and lipid concentrations in patients with type 1 diabetes. (1999) (47)
- Cytokines and T-lymphocyte subsets in healthy post-menopausal women: estrogen retards bone loss without affecting the release of IL-1 or IL-1ra. (1997) (47)
- Impact of Glycemic Control on Risk of Infections in Patients With Type 2 Diabetes: A Population-Based Cohort Study (2017) (46)
- Maximal lipid oxidation in patients with type 2 diabetes is normal and shows an adequate increase in response to aerobic training (2009) (46)
- Insulin Receptor Binding and Tyrosine Kinase Activity in Skeletal Muscle From Normal Pregnant Women and Women With Gestational Diabetes (1993) (46)
- Anthropometrics and Body Composition by Dual Energy X-Ray in Children of Obese Women: A Follow-Up of a Randomized Controlled Trial (the Lifestyle in Pregnancy and Offspring [LiPO] Study) (2014) (45)
- No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910–1989 (2011) (45)
- Aspects of glucose homeostasis in uremia as assessed by the hyperinsulinemic euglycemic clamp technique. (1985) (45)
- Decreased insulin binding to monocytes from normal pregnant women. (1979) (44)
- Outcomes in Type 1 Diabetic Pregnancies (2004) (44)
- Hyperglycaemia normalises insulin action on glucose metabolism but not the impaired activation of AKT and glycogen synthase in the skeletal muscle of patients with type 2 diabetes (2012) (44)
- Detection of hypoglycemia associated EEG changes during sleep in type 1 diabetes mellitus. (2012) (43)
- Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers (2015) (43)
- Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes. (2018) (43)
- Effects of hyperglycaemia on kidney function, atrial natriuretic factor and plasma renin in patients with insulin-dependent diabetes mellitus. (1991) (42)
- Effects of prolonged Acipimox treatment on glucose and lipid metabolism and on in vivo insulin sensitivity in patients with non-insulin dependent diabetes mellitus. (1992) (42)
- Effect of insulin on renal sodium handling in hyperinsulinaemic Type 2 (non-insulin-dependent) diabetic patients with peripheral insulin resistance (1991) (41)
- A novel oral form of salmon calcitonin improves glucose homeostasis and reduces body weight in diet‐induced obese rats (2011) (41)
- Elevated Atherosclerosis-Related Gene Expression, Monocyte Activation and Microparticle-Release Are Related to Increased Lipoprotein-Associated Oxidative Stress in Familial Hypercholesterolemia (2015) (41)
- Metabolic effects of lifestyle intervention in obese pregnant women. Results from the randomized controlled trial ‘Lifestyle in Pregnancy’ (LiP) (2014) (41)
- Characterization of Human Myotubes From Type 2 Diabetic and Nondiabetic Subjects Using Complementary Quantitative Mass Spectrometric Methods* (2011) (41)
- Risk of lactic acidosis in type 2 diabetes patients using metformin: A case control study (2018) (40)
- The reduced insulin-mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin--evidence from cultured myotubes. (2004) (40)
- Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with Type 2 (non-insulin-dependent) diabetes mellitus (2004) (40)
- Insulin Sensitivity and Carotid Intima-Media Thickness: Relationship Between Insulin Sensitivity and Cardiovascular Risk Study (2013) (40)
- Increased metabolic risk in adolescent offspring of mothers with type 1 diabetes: the EPICOM study (2015) (39)
- Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations. (1994) (39)
- Multiple insulin injections using a pen injector versus insulin pump treatment in young diabetic patients. (1987) (39)
- Population based study of prevalence of islet cell autoantibodies in monozygotic and dizygotic Danish twin pairs with insulin dependent diabetes mellitus (1997) (38)
- A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance (2014) (38)
- Absorption of NPH (Isophane) Insulin in Resting Diabetic Patients: Evidence for Subcutaneous Injection in the Thigh as the Preferred Site (1991) (38)
- OAS 1 Splice Site Polymorphism Controlling Antiviral Enzyme Activity Influences Susceptibility to Type 1 Diabetes (2005) (37)
- Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: A randomized controlled trial (the RECORD study) (2008) (37)
- Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes. (2004) (36)
- Pathophysiology‐based phenotyping in type 2 diabetes: A clinical classification tool (2018) (36)
- Rising prevalence of diabetes: evidence from a Danish pharmaco-epidemiological database. Commentary (2003) (36)
- Insulin resistance, but normal basal rates of glucose production in patients with newly diagnosed mild diabetes mellitus. (1991) (36)
- Glucose uptake and pulsatile insulin infusion: euglycaemic clamp and [3-3H]glucose studies in healthy subjects. (1986) (36)
- Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment. (2008) (36)
- Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project cohort of newly diagnosed patients with type 2 diabetes: a cohort profile (2018) (36)
- Is hepatic glucose production increased in type 2 diabetes mellitus? (2002) (36)
- Rates of Community-based Antibiotic Prescriptions and Hospital-treated Infections in Individuals With and Without Type 2 Diabetes: A Danish Nationwide Cohort Study, 2004-2012. (2016) (36)
- Plasma osteoprotegerin is related to carotid and peripheral arterial disease, but not to myocardial ischemia in type 2 diabetes mellitus (2011) (35)
- Effect of insulin on protein phosphatase 2A expression in muscle in type 2 diabetes (2002) (35)
- The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure. (2001) (35)
- Osteoprotegerin Levels in Primary Hyperparathyroidism: Effect of Parathyroidectomy and Association with Bone Metabolism (2003) (35)
- Insulin Resistance and Insulin-Dependent Diabetes Mellitus (1987) (35)
- Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects. (2006) (35)
- The Effects of Metformin on Adipocyte Insulin Action and Metabolic Control in Obese Subjects with Type 2 Diabetes (1989) (35)
- Pharmacological Treatment of the Pathogenetic Defects in Type 2 Diabetes (2010) (34)
- Insulin Receptors on Monocytes from Patients with Ketosis-prone Diabetes Mellitus (1978) (34)
- Insulin receptor binding and receptor-mediated insulin degradation in human adipocytes (1981) (34)
- Glucose-mediated glucose disposal in insulin-resistant normoglycemic relatives of type 2 diabetic patients. (2000) (34)
- Biological variation of serum and urinary magnesium in apparently healthy males. (1995) (33)
- Effect of short-term hyperglycemia per se on nociceptive and non-nociceptive thresholds (1994) (33)
- Cytokine RNA levels in transiliac bone biopsies from healthy early postmenopausal women. (2000) (32)
- Evidence-based insulin treatment in type 1 diabetes mellitus. (2009) (32)
- The antiviral 2',5'-oligoadenylate synthetase is persistently activated in type 1 diabetes. (2000) (32)
- A prospective study of twinning and perinatal mortality in urban Guinea-Bissau (2012) (32)
- Intracellular skeletal muscle glucose metabolism is differentially altered by dexamethasone treatment of normoglycemic relatives of type 2 diabetic patients. (1999) (32)
- Lack of effect of mianserin on the symptoms of diabetic neuropathy (2006) (32)
- GLUT11, but not GLUT8 or GLUT12, is expressed in human skeletal muscle in a fibre type-specific pattern (2004) (32)
- Mechanisms of Insulin Resistance in Non-Oxidative Glucose Metabolism: The Role of Glycogen Synthase (1998) (31)
- Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with Type 2 (non-insulin-dependent) diabetes mellitus (1993) (31)
- The Role of the Liver in Type 2 Diabetes (2004) (31)
- The role of genetic variants in CYP2C8, LPIN1, PPARGC1A and PPAR&ggr; on the trough steady-state plasma concentrations of rosiglitazone and on glycosylated haemoglobin A1c in type 2 diabetes (2013) (31)
- Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes. (2002) (31)
- Changes in patient weight and the impact of antidiabetic therapy during the first 5 years after diagnosis of diabetes mellitus (2006) (31)
- Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes. (2010) (30)
- Insulin resistance in skeletal muscles of patients with diabetes mellitus. (1989) (30)
- Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project (2015) (30)
- Long-term Cognitive Implications of Intrauterine Hyperglycemia in Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study) (2016) (30)
- The epidemic of type 2 diabetes is a statistical artefact (2005) (30)
- [Insulin resistance: organ manifestations and cellular mechanisms]. (2002) (30)
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- GLUT4 expression in human muscle fibres is not correlated with intracellular triglyceride (TG) content. Is TG a maker or a marker of insulin resistance? (2003) (16)
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- Antithrombin III activity, von Willebrand factor antigen and platelet function in young diabetic patients treated with multiple insulin injections versus insulin pump treatment (1989) (8)
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- No difference in insulin stimulated AKT and AS160 phosphorylation but decreased insulin effect on FoxO4 abundance in skeletal muscle of obese and obese type 2-diabetic subjects (2014) (1)
- Increased alanine aminotransferase levels and associated characteristics among newly diagnosed type 2 diabetes patients: Results from the DD2 study (2013) (0)
- University of Southern Denmark Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age (2016) (0)
- [New actors in type 2 diabetes]. (2002) (0)
- JAMA Peer Reviewers for 2003 (2017) (0)
- STATUS: THE DANISH CENTER FOR STRATEGIC REASEARCH IN TYPE 2 DIABETIS - THE DD2 STUDY (2013) (0)
- Pioglitazone, but not balaglitazone, negatively affects bone formation rates in male dio rats (2009) (0)
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- [Insulin receptors and the effect of insulin. Possible pathogenetic significance of abnormalities of insulin receptors and post-receptor function in diabetes mellitus and other insulin-resistant conditions]. (1986) (0)
- Hepatic Glucose Production Increases in Response to Metformin Treatment in the Glycogen-depleted State (2015) (0)
- Genetically Determined Insulin Resistance is Characterized by Down-Regulation of Mitochondrial Oxidative Metabolism in Human Skeletal Muscle (2010) (0)
- [Low-carbohydrate diet for patients with Type 2 diabetes]. (2016) (0)
- High prevalence of the metabolic syndrome among newly diagnosed type 2 diabetes patients in Denmark (2013) (0)
- The role of Parental and Family Support for Emerging Adults with Type 1 Diabetes: A Scoping Review (2020) (0)
- Interleukin-1β and interleukin-1 receptor antagonist gene expression in bone: Correlation with bone loss in healthy postmenopausal women (2006) (0)
- Lifestyle, pregnancy and off-spring; the Lipo Study (2011) (0)
- Statement of Retraction. The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes. Diabetes 2010;59:1870–1878. DOI: 10.2337/db09-1503. PMID: 20460426 (2017) (0)
- The role of parental support for emergineg adults with type 1 diabetes: A qualitative interview study (2020) (0)
- [Pseudohyperparathyreoidism in adenocarcinoma of the ovary. The diagnostic value of bone biopsy]. (1975) (0)
- [Genetic research--a research field in progress]. (2000) (0)
- Genetic characterisation of type II diabetic patients with prognostic markers (2007) (0)
- Retraction Note: Abstracts of the 47th Annual Meeting of the EASD, Lisbon 2011. ‘Reduced syntaxin-5 in skeletal muscle of patients with type 2 diabetes is linked to increased diacylglycerol, activation of PKCtheta and impaired insulin signalling’ (2014) (0)
- Insulin resistance: a risk factor for diabetic complications. (1990) (0)
- [Diabetic renal disease--is prevention possible? A review based on studies of renal function]. (1984) (0)
- Diagnosing or determining predisposition of a disease relating to diabetes in a human, by measuring level of a protein e.g. ATP synthase (-subunit, phosphoglucomutase 1, in biological sample: Publication documents (2003) (0)
- Genetic and environmental effects on body mass index from infancy until the onset of adulthood: A global perspective based on an individual-level analysis of 45 twin cohorts in the CODATwins study (2017) (0)
- Comparison of Treatment with Insulin Degludec and Glargine U100 in Patients with Type 1 Diabetes Prone to Nocturnal Severe Hypoglycaemia (HypoDeg): A Prospective, Randomized, Open-Label, Crossover Trial (2020) (0)
- The Combined Effect of Triple Therapy with Rosiglitazone, Metformin, and Insulin Aspart in Type 2 Diabetic Patients: Response to Davidson and Mikhail (2004) (0)
- P-80: The effect of insulin on phosphotyrosine phosphatase activity in skeletal muscle fractions from NIDDM patients and control subjects (2009) (0)
- Carotid Artery Stiffness Decreases with Habitual Physical Activity in a Healthy Adult Population (2005) (0)
- A reduced-carbohydrate diet high in monounsaturated fats in type 2 diabetes: A six-month study of changes in metabolism, liver- and cardiovascular function (reduction) (2016) (0)
- Do Genetic Factors Contribute to Variation in Insulin and Glucose Levels (2001) (0)
- Monocyte-derived microparticles are elevated in patients with familial hypercholesterolemia: a potential atherosclerosis risk marker (2013) (0)
- P283 THE ROLE OF SNARE PROTEINS IN HUMAN INSULIN RESISTANCE (2010) (0)
- Pathogenesis of non-insulin dependent diabetes mellitus (1983) (0)
- [The effect of captopril, metoprolol and hydrochlorothiazide therapy in patients with non-insulin-dependent diabetes (NIDDM) and primary hypertension. A double-blind, randomized cross-over study]. (1993) (0)
- Diabetes diagnosis leads to weight loss (2019) (0)
- glycogen contents uptake and glycogen synthase in muscle with different Additive effect of contraction and insulin on glucose (2015) (0)
- Prevalence of elevated C-reactive protein among newly diagnosed type 2 diabetes patients in Denmark: Results from the population-based DD2 study (2013) (0)
- P-78 Estimates of the bioactivity of IGF-II in serum from healthy subjects, obese subjects and obese type 2 diabetic patients (2008) (0)
- P-116: Physical fitness, body composition and intraabdominal fat: Relation to insulin resistance and insulin secretion in relatives of patients with NIDDM (2009) (0)
- Natural history of non-insulin dependent diabetes mellitus (1983) (0)
- Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers (2015) (0)
- [Thiazolidinediones- - new class of oral antidiabetics]: Thiazolidinedioner- en ny klasse af orale antidiabetika (2001) (0)
- Elevated endothelial-derived microparticles in patients with familial hypercholesterolemia: potential marker of endothelial dysfunction (2013) (0)
- Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment. (2023) (0)
- [Animal experiments in medical research]. (1999) (0)
- Mannose-binding lectin and risk of infections in type 2 diabetes: A Danish cohort study. (2021) (0)
- Study of phenotypic characteristics of patients with latent autoimmune diabetes in adults (LADA) in a Danish population (2012) (0)
- Patients with latent autoimmune diabetes: Studies on phenotypic characteristics, treatment and outcome (2015) (0)
- Comparison of insulin degludec and glargine U100 in patients with type 1 diabetes prone to severe nocturnal hypoglycaemia (2020) (0)
- Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of twin (2016) (0)
- Farmakoøkonomiske evalueringer af osteoporosebehandling (2002) (0)
- [Diabetes mellitus and acute myocardial infarction]. (1983) (0)
- P-119: Etiology of NIDDM: Genetics versus pre- or post natal environments? Results from twin studies (2009) (0)
- [Injection site for quick-acting insulin. Significance for glycemic control in basal bolus insulin regimen]. (1994) (0)
- [Give them a pill?]. (2000) (0)
- Detection of spontanewous, insulin induced and nocturnal hypoglycaemia by automated analysis of EEG in patients with type 1 diabetes (2009) (0)
- Insulin stimulates FoxO4 protein abundance in human skeletal muscle in lean healthy but not in obese subjects with or without type 2 diabetes (2014) (0)
- [Insulin receptors. A new understanding of the physiopathological mechanisms in the development of insulin resistance in overweight persons]. (1981) (0)
- Urinary tract problems among aged women in nursing homes can often be treated by educational measures (1991) (0)
- Abstract: Outcomes in type-1 diabetic pregnancies: A nationwide population based Study (2002) (0)
- The effect of controlled hyperglycemia on pain and sensory thresholds (1991) (0)
- Fatty Liver Disease among Adolescent Offspring Born to Women with Pregestational Type 1 Diabetes (The EPICOM Study) (2018) (0)
- Vaegtanamnesen for patienter med nyopdaget type 2-diabetes--sekundaerpublikation (2008) (0)
- [Rising prevalence and decreasing mortality of diabetes in the county of Funen]. (2004) (0)
- CRP, C-Peptide, and Risk of First-Time Cardiovascular Events and Mortality in Early Type 2 Diabetes: A Danish Cohort Study. (2023) (0)
- Epigenetic Differences in Monozygotic Twins Discordant for Type 2 Diabetes (2009) (0)
- Cardiovascular disease in type 2 diabetes mellitus: prevalence of ischemic heart, carotid, and peripheral arterial disease (2008) (0)
- Syddansk Universitet The Impact of Lipoprotein-Associated Oxidative Stress on Cell-Specific Microvesicle Release in Patients with Familial Hypercholesterolemia (2016) (0)
- Mutation in the Human Insulin Receptor Gene A Novel Syndrome of Autosomal-Dominant Hyperinsulinemic Hypoglycemia Linked to a (2015) (0)
- Maternal weight retention two years postpartum – results from the LiP and LiPO study (2012) (0)
- Authors' reply (1996) (0)
- A novel oral form of salmon Calcitonin improves glucose homeostasis and preserves pancreatic secretory function in Zucker diabetic fatty rats (2012) (0)
- Increased insulin mediated glycogen synthase activation in skeletal muscle is not responsible for the elevated glucose storage seen in type 2 diabetic patients treated with troglitazone (2000) (0)
- [Islet transplantation in type 1 diabetes. Status and perspectives]. (2003) (0)
- Evidence for an association between diabetes and birth weight still exists (1999) (0)
- University of Southern Denmark Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age (2015) (0)
- PP131—Interaction between polymorphisms in Oct2 and mate1 and metformin renal clearance (2013) (0)
- Abstract: Outcomes in type-1 diabetic pregnancies: A nationwide population based Study (2002) (0)
- Prediction of Nonsevere Hypoglycemia—The Influence of Glycemic Variability in the HypoAna Study (2018) (0)
- PHARMACOGENETICS OF METFORMIN (2010) (0)
- Erratum (2012) (0)
- CD36 positive microparticles in plasma are derived from several cell-types (2012) (0)
- Effect of insulin degludec versus insulin glargine U100 on nocturnal glycaemia assessed by plasma glucose profiles in people with type 1 diabetes prone to nocturnal severe hypoglycaemia (2023) (0)
- Treatment of the Metabolic Syndrome in Daily Clinical Practice: Algorithms (2013) (0)
- Association between routine laboratory tests and long-term mortality among acutely admitted older medical patients (2018) (0)
- National normative curves for abdominal circumference and weight at birth adjusted for maternal pregestational BMI and smoking (2012) (0)
- Congenital Generalized lipodystrophy (2018) (0)
- Clinical metabolic data for type 2 diabetic and obese patients and sedentary control subjects (2000) (0)
- Metformin associated lactic acidosis-incidence in the years of 2004-2012 (2015) (0)
- South Danish Diabetes Study: Effect of antidiabetic treatment on cardiovascular risk factors (2007) (0)
- EValuaTioN of ThE iNfluENCE of CyToCromE P 450 oxidorEduCTaSE ( Por ) iN ThE STablE doSE of aCENoCoumarol (2013) (0)
- [Prevention of non-insulin-dependent diabetes mellitus]. (1997) (0)
- Twin Studies in Metabolic Disease: Type 2 Diabetes and the Metabolic Syndrome (2001) (0)
- Mechanism of action of thiazolidinediones in type II diabetes: Insulin Resistance,Metabolic Diseases and Diabetic Complications (1999) (0)
- Endurance exercise training rescues impaired TBC1D4 phosphorylation in skeletal muscle of T2D patients (2009) (0)
- [Weight changes and the effect of anti-diabetes treatment in the first 5 years after diabetes diagnosis - secondary publication]. (2006) (0)
- [Insulin treatment--its physiological principle]. (1992) (0)
- The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Study Cohort: Presentation of 5,870 Patients with New Type 2 Diabetes Enrolled from 2010 Through 2014 (2016) (0)
- O.19 Triglyceride induced diabetes mellitus (1997) (0)
- Analysis of eeg signals for detection hypoglycaemia (2007) (0)
- Lavkulhydratdiæt til patienter med type 2-diabetes (2016) (0)
- [The metabolic syndrome in the daily clinic]. (2010) (0)
- Akt influences glycogen synthase in skeletal muscle through regulation of NH2-terminal phosphorylation (2010) (0)
- Elevated Monocyte-derived microparticles in patients with familial hypercholesterolemia: A potential atherosclerosis risk marker (2013) (0)
- A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle (2022) (0)
- Thirty-day mortality following admission with lactic acidosis in diabetes patients using metformin: a Danish nationwide study (2018) (0)
- [Endocrinology--toward the next century]. (1999) (0)
- [Weight history of patients with newly diagnosed type 2 diabetes--secondary publication]. (2008) (0)
- Syddansk Universitet Assessment of Attention Deficits in Adolescent Offspring Exposed to Maternal Type 1 (2017) (0)
- [A 20-year prospective study of osteoporosis--is it necessary?]. (1991) (0)
- Mannan-binding lectin and cardiovascular events and mortality in type 2 diabetes: a cohort study of 7,307 patients in the Danish DD2 cohort (2019) (0)
- Using the Brain as a Biosensor to Detect Hypoglycaemia (2011) (0)
- Treatment of a patient with diabetes and severe hypoglycaemia (2015) (0)
- Oscillations of C-peptide and insulin in insulin resistant first-degree realtives of NIDDM patients are conserved (1999) (0)
- Proceedingsof the 7th European Symposium on Metabolism (1999) (0)
- University of Southern Denmark The Impact of Lipoprotein-Associated Oxidative Stress on Cell-Specific Microvesicle Release in Patients with Familial Hypercholesterolemia (2016) (0)
- Noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) caused by an activating glucokinase mutation (2006) (0)
- [Metformin and surgery before general anaesthesia]. (2018) (0)
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