Henning Walczak

Q: What Schools Are Affiliated With Henning Walczak

Henning Walczak is affiliated with the following schools: University of Sheffield, University of Cologne, University of Oxford, University College London, Imperial College London, Stanford University

Henning Walczak's AcademicInfluence.com Rankings

Henning Walczak

Biology

#9220

World Rank

#12398

Historical Rank

Biotechnology

#122

World Rank

#124

Historical Rank

Molecular Biology

#1235

World Rank

#1261

Historical Rank

Biochemistry

#1385

World Rank

#1509

Historical Rank

biology Degrees

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Biology

Henning Walczak's Degrees

Bachelors Biotechnology Imperial College London

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Henning Walczak's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo (1999) (2565)
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) (1995) (1789)
Regulated necrosis: the expanding network of non-apoptotic cell death pathways (2014) (1327)
TRAIL‐R2: a novel apoptosis‐mediating receptor for TRAIL (1997) (1184)
Rethinking ovarian cancer: recommendations for improving outcomes (2011) (1148)
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120 (1995) (1039)
Cell Death (2010) (916)
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. (2000) (830)
Linear ubiquitination prevents inflammation and regulates immune signalling (2011) (824)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. (1997) (794)
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. (2003) (759)
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage (1995) (731)
Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family (1997) (701)
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. (2009) (696)
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. (2000) (661)
TRAIL signalling: decisions between life and death. (2007) (470)
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury (2013) (458)
Cell nucleus and DNA fragmentation are not required for apoptosis (1994) (439)
Caspase-8 and bid: caught in the act between death receptors and mitochondria. (2011) (433)
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation (2017) (425)
Caspase‐10 is recruited to and activated at the native TRAIL and CD95 death‐inducing signalling complexes in a FADD‐dependent manner but can not functionally substitute caspase‐8 (2002) (403)
Getting TRAIL back on track for cancer therapy (2014) (379)
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy (2017) (357)
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. (2012) (338)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. (2000) (315)
Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis (2000) (291)
Following TRAIL’s path in the immune system (2009) (287)
CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitis. (1997) (264)
The Role of APO‐1‐Mediated Apoptosis in the Immune System (1994) (253)
NF-κB-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas/FasL Is Crucial for Efficient Influenza Virus Propagation* (2004) (252)
Onto better TRAILs for cancer treatment (2016) (250)
TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis (2009) (235)
Preclinical Differentiation between Apparently Safe and Potentially Hepatotoxic Applications of TRAIL Either Alone or in Combination with Chemotherapeutic Drugs (2006) (232)
Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy. (2001) (232)
TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer (2011) (224)
The interplay between the Bcl-2 family and death receptor-mediated apoptosis. (2004) (223)
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice (2014) (219)
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes (2015) (216)
Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury (2004) (212)
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs (2004) (211)
Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4 (2008) (210)
The promise of TRAIL—potential and risks of a novel anticancer therapy (2007) (199)
Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells. (2000) (197)
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. (2008) (196)
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death. (2014) (190)
Death receptor-ligand systems in cancer, cell death, and inflammation. (2013) (179)
Generation and physiological roles of linear ubiquitin chains (2012) (177)
CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells (2001) (172)
Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL (2005) (170)
Structure of the human APO‐1 gene (1994) (169)
Ubiquitin in the immune system (2013) (167)
Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. (2008) (158)
Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma. (2009) (158)
T cells require TRAIL for optimal graft-versus-tumor activity (2002) (157)
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis. (2015) (155)
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2 (2017) (155)
Necroptosis in Immunity and Ischemia‐Reperfusion Injury (2013) (153)
Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency (2017) (153)
Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma. (2006) (152)
Linear ubiquitination: a newly discovered regulator of cell signalling. (2013) (151)
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation (2018) (147)
NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions (2016) (142)
Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter. (2002) (139)
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis (2018) (138)
Is TRAIL the holy grail of cancer therapy? (2009) (137)
Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells. (2010) (136)
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling. (2016) (127)
Bortezomib Sensitizes Primary Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis (2007) (126)
TRAIL: a multifunctional cytokine. (2007) (125)
Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing (2013) (125)
Lidocaine Induces Apoptosis via the Mitochondrial Pathway Independently of Death Receptor Signaling (2007) (124)
CD 28-dependent Rac 1 activation is the molecular target of azathioprine in primary human CD 4 + T lymphocytes (2003) (122)
Lack of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand But Presence of Its Receptors in the Human Brain (2002) (121)
Failure of Bcl‐2 to block cytochrome c redistribution during TRAIL‐induced apoptosis (2000) (121)
Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation (2003) (121)
Linear ubiquitination in immunity (2015) (116)
Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis (2008) (113)
Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells. (2014) (113)
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes (2016) (113)
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer‐specific apoptosis within a therapeutic window (2007) (112)
Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis. (2000) (111)
Poly-ubiquitination in TNFR1-mediated necroptosis (2016) (107)
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development (2017) (106)
TNF-Related Apoptosis-Inducing Ligand Mediates Tumoricidal Activity of Human Monocytes Stimulated by Newcastle Disease Virus 1 (2003) (106)
Target cell‐restricted and ‐enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma‐associated antigen EGP2 (2004) (105)
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1 (2013) (105)
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release (2001) (101)
Cell surface sialylation plays a role in modulating sensitivity towards APO-1-mediated apoptotic cell death. (1995) (95)
TRAIL and other TRAIL receptor agonists as novel cancer therapeutics. (2009) (91)
TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections. (2002) (90)
Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer (2009) (86)
Herpes Simplex Virus Type 1 Infection of Activated Cytotoxic T Cells: Induction of Fratricide as a Mechanism of Viral Immune Evasion (1999) (86)
The Emerging Role of Linear Ubiquitination in Cell Signaling (2011) (85)
Biochemistry and function of the DISC. (2001) (84)
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib (2010) (83)
Differences between CD95 type I and type II cells detected with the CD95 ligand [1] (1999) (83)
UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases (2015) (82)
The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death (2017) (79)
Biochemical analysis of the native TRAIL death-inducing signaling complex. (2008) (77)
NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2. (2008) (76)
TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: differential contribution of TRAIL receptors 1 and 2. (2003) (73)
A regulatory element in the CD95 (APO‐1/Fas) ligand promoter is essential for responsiveness to TCR‐mediated activation (1998) (72)
Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: Sensitivity of human thymocytes (2001) (71)
APO-1 (CD95)-dependent and -independent antigen receptor-induced apoptosis in human T and B cell lines. (1995) (71)
Death receptors as targets for anti-cancer therapy (2008) (70)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma (2021) (68)
Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells (2000) (67)
Polymeric substrates with tunable elasticity and nanoscopically controlled biomolecule presentation. (2010) (66)
Cell Death and Inflammation - A Vital but Dangerous Liaison. (2019) (66)
TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells (2014) (66)
Paneth cells express high levels of CD95 ligand transcripts: a unique property among gastrointestinal epithelia. (1996) (66)
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan (2000) (65)
Prognostic Value of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) and TRAIL Receptors in Renal Cell Cancer (2009) (63)
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation (2016) (63)
ICE-proteases mediate HTLV-I Tax-induced apoptotic T-cell death (1997) (63)
No one can whistle a symphony alone – how different ubiquitin linkages cooperate to orchestrate NF-κB activity (2012) (62)
Identification of PP2A as a crucial regulator of the NF-κB feedback loop: its inhibition by UVB turns NF-κB into a pro-apoptotic factor (2008) (61)
cFLIPL Inhibits Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated NF-κB Activation at the Death-inducing Signaling Complex in Human Keratinocytes* (2004) (60)
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L (2018) (58)
Caspases : their role in cell death and cell survival (2002) (57)
Caspases Target Only Two Architectural Components within the Core Structure of the Nuclear Pore Complex* (2006) (53)
The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway (2008) (53)
Linear ubiquitination at a glance (2019) (53)
Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway (2008) (53)
Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity (2013) (52)
Herpes Simplex Virus Type 1 Infection of Activated Cytotoxic T Cells (1999) (51)
Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination (2013) (51)
The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19. (1992) (51)
CD95 ligand (CD95L) immunohistochemistry: a critical study on 12 antibodies (2001) (51)
Sensitive and real-time determination of H2O2 release from intact peroxisomes. (2002) (50)
Critical role for mitochondria in B cell receptor-mediated apoptosis. (2000) (50)
Micro-nanostructured protein arrays: a tool for geometrically controlled ligand presentation. (2009) (48)
Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing. (2007) (48)
Differences between CD95 type I and II cells detected with the CD95 ligand. (1999) (48)
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila (2018) (48)
Zebrafish Model for Functional Screening of Flow-Responsive Genes (2016) (42)
CD95 ligand (CD95L) in normal human lymphoid tissues: a subset of plasma cells are prominent producers of CD95L. (1999) (41)
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis (2016) (41)
Protective effect of Mangifera indica L. polyphenols on human T lymphocytes against activation-induced cell death. (2007) (40)
Activated T killer cells induce apoptosis in lung epithelial cells and the release of pro‐inflammatory cytokine TNF‐α (2004) (40)
Apoptosis therapy: driving cancers down the road to ruin (2013) (40)
TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy. (2006) (38)
CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling (2009) (36)
Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout (2014) (35)
Cutting Edge: Resistance to Apoptosis and Continuous Proliferation of Dendritic Cells Deficient for TNF Receptor-11 (2000) (35)
The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1β secretion in macrophages. (2015) (34)
Paving TRAIL's Path with Ubiquitin. (2018) (34)
Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. (2019) (33)
In Chronic Pancreatitis, Widespread Emergence of TRAIL Receptors in Epithelia Coincides with Neoexpression of TRAIL by Pancreatic Stellate Cells of Early Fibrotic Areas (2003) (33)
The caspase family (2003) (32)
Critical role for mitochondria in B cell receptor‐mediated apoptosis (2000) (30)
Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10 (2014) (29)
Formation and removal of poly‐ubiquitin chains in the regulation of tumor necrosis factor‐induced gene activation and cell death (2016) (29)
IL-24 sensitizes tumor cells to TLR3-mediated apoptosis (2013) (29)
Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A. (2010) (27)
Transforming growth factor β can mediate apoptosis via the expression of TRAIL in human hepatoma cells (2005) (27)
Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease. (2010) (27)
Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors (2006) (25)
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells (2018) (23)
Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism (2014) (23)
Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma (2013) (22)
Monitoring of CD95 (APO-1/Fas) ligand expression in human T cells by quantitative RT-PCR. (1996) (22)
TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells (2002) (21)
Simultaneous in situ detection of mRNA and apoptotic cells by combined hybridization and TUNEL. (1996) (20)
The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis (2017) (20)
Bortezomib Sensitizes Primary Meningioma Cells to TRAIL-Induced Apoptosis by Enhancing Formation of the Death-Inducing Signaling Complex (2014) (20)
Tumor Necrosis Factor-related Apoptosis-inducing Ligand Retains Its Apoptosis-inducing Capacity on Bcl-2-or Bcl-xL-overexpressing Chemotherapy-resistant Tumor Cells 1 (2000) (19)
Opposing role of tumor necrosis factor receptor 1 signaling in T cell–mediated hepatitis and bacterial infection in mice (2016) (19)
Molecular mechanisms of APO-1/Fas(CD95)-mediated apoptosis in tolerance and AIDS. (1995) (19)
Death Receptors and Their Ligands in Inflammatory Disease and Cancer. (2020) (19)
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis (2017) (19)
Vacuolar transport of the glutathione conjugate of trans-cinnamic acid. (2000) (19)
Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis (2010) (18)
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury (2019) (17)
Mangifera indica L. extract protects T cells from activation-induced cell death. (2006) (17)
Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus (2015) (17)
Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD (2008) (17)
NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II (2016) (16)
An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer (2020) (15)
Apoptosis mediated by lentiviral TRAIL transfer involves transduction-dependent and -independent effects (2007) (14)
The two CD95 apoptosis signaling pathways may be a way of cells to respond to different amounts and/or forms of CD95 ligand produced in different tissues (2000) (14)
The linear ubiquitin chain assembly complex forms part of the TNF-R1 signalling complex and is required for effective TNF-induced gene induction and prevents TNF-induced apoptosis. (2011) (14)
Transforming growth factor beta can mediate apoptosis via the expression of TRAIL in human hepatoma cells. (2005) (14)
Helicobacter pylori‐induced apoptosis in T cells is mediated by the mitochondrial pathway independent of death receptors (2007) (14)
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis (2021) (13)
Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway (2015) (13)
WHO grade related expression of TRAIL-receptors and apoptosis regulators in meningioma. (2015) (12)
Hypochlorite-modified low-density lipoprotein induces the apoptotic machinery in Jurkat T-cell lines (2011) (11)
Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection. (2014) (10)
Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers (2021) (9)
The TRAIL Receptor‐Ligand System: Biochemistry of Apoptosis Induction, Therapeutic Potential for Cancer Treatment and Physiological Function (2008) (9)
TRAIL Dependent Fratricidal Killing of gp120 Primed Hepatocytes by HCV Core Expressing Hepatocytes (2011) (9)
Activation-induced T cell death (1996) (9)
Compound heterozygous variants in OTULIN are associated with fulminant atypical late‐onset ORAS (2022) (7)
Fluorogenic substrates as detectors of caspase activity during natural killer cell-induced apoptosis. (2000) (7)
Sterile Inflammation Fuels Gastric Cancer. (2018) (6)
Superantigen reactive Vβ6+ T cells induce perforin/granzyme B mediated caspase-independent apoptosis in tumour cells (2002) (6)
Dual Philosophy in Death Receptor Signalling (2011) (6)
From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy. (2009) (6)
Bortezomib-Mediated Up-Regulation of TRAIL-R1 and TRAIL-R2 Is Not Necessary for but Contributes to Sensitization of Primary Human Glioma Cells to TRAIL (2007) (6)
TRAIL-receptor 2—a novel negative regulator of p53 (2021) (6)
TLRs Go Linear - On the Ubiquitin Edge. (2017) (6)
CD 95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling (2009) (5)
Advances in Brief Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand Sensitivity in Primary and Transformed Human Keratinocytes 1 (2000) (5)
Thiocolchicoside a semi‐synthetic derivative of the Glory Lily: a new weapon to fight metastatic bone resorption? (2012) (5)
Activation of KIT modulates the function of tumor necrosis factor‐related apoptosis‐inducing ligand receptor (TRAIL‐R) in mast cells (2015) (5)
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries (2022) (5)
Neoadjuvant Immunotherapy in Gastrointestinal Cancers - The New Standard of Care? (2022) (4)
Rocking cell death (1999) (4)
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation (2018) (4)
Bortezomib Sensitizes Human Astrocytoma Cells to Tumor Necrosis Factor-Related Apoptosis-lnducing Ligand : Induced Apoptosis. Authors' reply (2007) (4)
Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy. (2019) (3)
Faculty Opinions recommendation of A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. (2009) (3)
The effect of simulated drought on HVA1 and SRG6 gene expression in spring barley (2011) (3)
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets (2022) (3)
Generation and physiological roles of linear ubiquitin chains (2012) (3)
Dual roles for LUBAC signaling in thymic epithelial cell development and survival (2021) (2)
Ubiquitin in the immune system (2014) (2)
Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS‐CoV‐2 mRNA vaccination (2022) (2)
APO-I-mediated apoptosis in normal and malignant lymphocytes. (1994) (2)
Apoptosis induction by TRAIL. (2003) (2)
Educational Corner: Activation-induced T cell death. (1996) (1)
CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: A pathologenetic role for the CD9S/CD95 ligand-system in ulcerative colitis (1996) (1)
An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer (2020) (1)
The seven wonders of ubiquitin: a multi‐interview (2014) (1)
Abstract B13: The impact of combined CDK9 inhibition and TRAIL treatment on NSCLC (2018) (1)
Poly-ubiquitination in TNFR1-mediated necroptosis (2016) (1)
CD4/CXCR4-mediated cell death in AIDS (2007) (1)
“ Ubiquitylation : mechanism and functions ” Review series Ubiquitin in the immune system (2014) (1)
Post-traumatic coping with the loss of a child among women and men (2015) (1)
Glory Lily ' s semi-synthetic derivative Thiocolchicoside : a new weapon to fight metastatic bone resorption ? (2013) (1)
280 Proteasome inhibition sensitises hepatocellular carcinoma cells but not primary human hepatocytes for trail-induced apoptosis through increased caspase-8 cleavage at the disc independent from NF-KB (2004) (1)
Per aspera ad astra: from early T-cell development to accelerating late T-cell apoptosis (2006) (1)
T1 Loss of BAP1 function leads to TRAIL sensitivity in mesothelioma (2018) (1)
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L (2018) (1)
The TRAIL ( APO-2 L ) Apoptosis System (2002) (1)
TWO SEPARATE PATHWAYS OF REGULATED NECROSIS CONTRIBUTE TO ISCHEMIA-REPERFUSION INJURY (2013) (0)
Fc improved fusion proteins. (2004) (0)
LUBAC-mediated signals in thymic epithelial cells prevent early thymic atrophy and immunodeficiency (2018) (0)
Physiological role of linear ubiquitination: more to it than meets the eye (2019) (0)
O47. SLE Susceptibility Gene UBE2L3 Polymorphism Controls Sensitivity of NF-KB to TNF and CD40 In Vivo (2014) (0)
Receiver fixing trail. (1998) (0)
O37. The Autoimmune Risk Gene UBE2L3 is Highly Expressed During B Cell Proliferation and is Correlated with Plasmablast and Plasma Cell Expansion in SLE (2015) (0)
Immunological fingerprint in coronavirus disease-19 convalescents with and without post-COVID syndrome (2023) (0)
Deficient for TNF Receptor-1 Continuous Proliferation of Dendritic Cells Cutting Edge: Resistance to Apoptosis and (2000) (0)
A2.10 SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation of NF-κB (2015) (0)
The receptors that bind TRAIL (1998) (0)
[ON THE TREATMENT OF DIFFERENT TYPES OF RHEUMATIC DISEASES IN PULMONARY TUBERCULOSIS AND LUNG TUMORS]. (1964) (0)
Letter to the Editor (1999) (0)
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila (2018) (0)
TNF and Ubiquitination (2017) (0)
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair (2022) (0)
P09.18 TNF induction in essential for oncolytic influenza A virus induced cancer regression and tumor associated macrophage repolarization (2022) (0)
VirusMonocytes Stimulated by Newcastle Disease Mediates Tumoricidal Activity of Human TNF-Related Apoptosis-Inducing Ligand (2003) (0)
The First European Workshop on Cell Death: (Death on the Rocks) held at Gran Sasso, Italy, 21 - 25 October 1998. Rocking cell death. (1999) (0)
Means for inhibiting apoptosis (1994) (0)
Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation (2003) (0)
Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma (2013) (0)
Correction to: Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4 (2019) (0)
Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
Receptor que fija trail. (1998) (0)
Proteine se fixant a la proteine trail (1998) (0)
Faculty Opinions recommendation of RIP3 mediates the embryonic lethality of caspase-8-deficient mice. (2011) (0)
Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis (2023) (0)
Trail-induced apoptosis in human hepatoma cell lines in regulated at the disc via increased recruitment of caspase-8 and not at the mitochondrial level (2003) (0)
Preliminary report Mangifera indica L. extract protects T cells from activation-induced cell death (2006) (0)
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis (2017) (0)
UBE2L3 genotype Influences Plasma Cell Proliferation in Systemic Lupus Erythematosus By Regulation of NF-kappa B By the Linear Ubiquitination Assembly Complex. (2014) (0)
281 TGF-β is involved in the regulation of apoptosis via trail expression in hepatoma cells (2004) (0)
Novel TRAIL-based Therapies for Pancreatic Cancer (2019) (0)
Activation of DNAse X - A new candidate enzyme mediating DNA fragmentation during apoptosis. (1996) (0)
LUBAC is required for RIG-I sensing of RNA viruses (2022) (0)
Regulation of Death Receptor-Induced Necroptosis by Ubiquitination (2014) (0)
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis (2018) (0)
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma (2012) (0)
Primary human hepatocytes are resistant to trail-induced apptosis and are not sensitised for trail-induced apoptosis by chemotherapeutic drugs (2003) (0)
Gimap4 accelerates T-cell death. Commentary (2006) (0)
Characterization of the TNFR1-SC Using "Modified Tandem Affinity Purification" in Conjunction with Liquid Chromatography-Mass Spectrometry (LC-MS). (2018) (0)
TGF-beta-induced apoptosis can be mediated via TRAIL in hepatoma cells (2005) (0)
BSR AND BHPR ORAL PRESENTATION OF ABSTRACTS DURING B AND IS CORRELATED WITH PLASMABLAST AND PLASMA CELL EXPANSION IN SLE METHOTREXATE INDUCES EPIGENETIC MODIFICATION OF THE FOXP3 LOCUS IN CD4 þ CD25 REGULATORY T CELLS FROM PATIENTS WITH RHEUMATOID ARTHRITIS (2014) (0)
The European Death Flying Circus (2002) (0)
Proteines hybrides fc ameliorees (2004) (0)
We aim to refresh science, not to rebel (1998) (0)
[Normal colon epithelium is highly sensitive to CD95-induced apoptosis. Indication for a role of cell death-induced CD95/CL95L systems under inflammatory inflammatory conditions?]. (1996) (0)
Autocrine production of IL-4 confers resistance to chemotherapy and CD-95 induced cell death in cancer cells. (2006) (0)
260 POSTER A novel paradigm for apoptosis-based therapy of pancreatic cancer: sensitizer/inducer concept of XIAP inhibitors combined with TRAIL (2008) (0)
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury (2019) (0)
Non-destructive Imaging of Pathology in Mouse Embryos Using Micro-CT: Implications for Human Fetal Autopsy Practice (2016) (0)
Inhibitors of apoptosis (1994) (0)
289 Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta-mediated induction of tnf-related apoptosis-inducing ligand (2006) (0)
Increased TRAIL-resistance of pancreatic cancer stem cells (2008) (0)
Disc analysis of drug modulated sensitivity of human hepatoma cell lines for trail-induced apoptosis (2001) (0)
A TRAIL towards tumour therapy (1999) (0)
Trail receptor binding (1998) (0)
Apoptosis: Death Domain–Containing Receptors – Decisions between Suicide and Fire (2011) (0)
TRAIL-induced apoptosis: from analysis of the death-inducing signalling complex (DISC) to clinical applicability (2007) (0)
Death Receptor-Induced Apoptotic and Nonapoptotic Signaling (2014) (0)
Title: Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation Overline: Transplantation Single sentence summary: Mesenchymal stromal cell apoptosis, induced in vivo by recipient (2018) (0)
Gold nanoparticles: Small 9/2009 (2009) (0)
Abstract B18: Characterization and therapeutic harnessing of TRAIL’s pro-tumorigenic and pro-apoptotic functions in cancer (2018) (0)
Polycythemia vera erythroblasts: too tough to die (2006) (0)

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