Henry F. Mcfarland
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Henry F. Mcfarland's Degrees
- Doctorate Medicine Johns Hopkins University
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(Suggest an Edit or Addition)Henry F. Mcfarland's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis (2001) (6788)
- Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria” (2005) (5003)
- Multiple sclerosis: a complicated picture of autoimmunity (2007) (1028)
- Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand (2000) (809)
- Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. (1998) (632)
- Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. (2006) (599)
- Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA (1997) (478)
- Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients (2005) (466)
- Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis. (1995) (410)
- Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis (1993) (397)
- Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. (1990) (366)
- Identification of High Potency Microbial and Self Ligands for a Human Autoreactive Class II–restricted T Cell Clone (1997) (355)
- Using gadolinium‐enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis (1992) (341)
- Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. (2004) (320)
- Serial gadolinium‐enhanced magnetic resonance imaging scans in patients with early, relapsing‐remitting multiple sclerosis: Implications for clinical trials and natural history (1991) (316)
- A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis (1991) (285)
- The effect of interferon‐β on blood—brain barrier disruptions demonstrated by constrast‐enhanced magnetic resonance imaging in relapsing—remitting multiple sclerosis (1995) (251)
- Expansion and Functional Relevance of High-Avidity Myelin-Specific CD4+ T Cells in Multiple Sclerosis (2004) (247)
- CD4+CD28- costimulation-independent T cells in multiple sclerosis. (2001) (242)
- Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays (1999) (236)
- Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease (1999) (235)
- The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative (2016) (225)
- Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease. (2003) (218)
- Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens. (1984) (215)
- Changes in cerebral perfusion precede plaque formation in multiple sclerosis: a longitudinal perfusion MRI study. (2004) (211)
- Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis (2010) (200)
- HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells (1989) (197)
- Evolution of T1 black holes in patients with multiple sclerosis imaged monthly for 4 years. (2003) (188)
- Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genes (2001) (185)
- Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology. (1998) (184)
- Tissue distribution and variant characterization of human herpesvirus (HHV)-6: increased prevalence of HHV-6A in patients with multiple sclerosis. (2000) (176)
- Increases in soluble VCAM‐1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon β‐1b (1997) (174)
- Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis. (2003) (169)
- Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis. (2009) (168)
- Multiple sclerosis : clinical and pathogenetic basis (1997) (163)
- Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106. (1992) (158)
- Magnetic resonance imaging of labeled T‐cells in a mouse model of multiple sclerosis (2004) (156)
- Relationship of cortical atrophy to fatigue in patients with multiple sclerosis. (2010) (146)
- The germline repertoire of T cell receptor β-chain genes in patients with chronic progressive multiple sclerosis (1989) (145)
- Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions (2001) (145)
- T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes. (1993) (143)
- Gender differences in autoimmune demyelination in the mouse: Implications for multiple sclerosis (1996) (143)
- Age-dependent resistance to viral encephalitis: studies of infections due to Sindbis virus in mice. (1972) (138)
- Characterization of MRI response to treatment with interferon beta-1b: Contrast-enhancing MRI lesion frequency as a primary outcome measure (1997) (132)
- Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis (1993) (129)
- Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients (2000) (129)
- Interferon beta-1b and intravenous methylprednisolone promote lesion recovery in multiple sclerosis (2001) (126)
- VLA-4 expression on peripheral blood lymphocytes is downregulated after treatment of multiple sclerosis with interferon beta (1997) (123)
- Multiple sclerosis in twins (1980) (123)
- The role of MRI as a surrogate outcome measure in multiple sclerosis (2002) (117)
- Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire. (1997) (116)
- Hereditary adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. (1984) (116)
- Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS (1998) (113)
- Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity (1999) (111)
- Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis. (1997) (109)
- Training-dependent plasticity in patients with multiple sclerosis. (2004) (106)
- Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells. (1997) (104)
- The Immune Response to Viruses (1989) (104)
- Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87–99) (1996) (103)
- Blood‐brain barrier disruption on contrast‐enhanced MRI in patients with mild relapsing‐remitting multiple sclerosis (1995) (102)
- Serial contrast‐enhanced magnetic resonance imaging in patients with early relapsing–remitting multiple sclerosis: Implications for treatment trials (1994) (101)
- Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR Vβ chain locus and HLA class II genes (1993) (95)
- Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis. (2009) (94)
- In vivo detection of cortical plaques by MR imaging in patients with multiple sclerosis. (2006) (92)
- SPECIFICITY OF THE INFLAMMATORY RESPONSE IN VIRAL ENCEPHALITIS (1972) (92)
- Preferential expansion of autoreactive T lymphocytes from the memory T-cell pool by IL-7 (1999) (90)
- Megadose corticosteroids in multiple sclerosis (1994) (88)
- Immunopathogenesis of the multiple sclerosis lesion (2001) (87)
- A pilot study of recombinant insulin-like growth factor-1 in seven multiple sclerosis patients (2002) (85)
- Central nervous system disease in primary Sjögren’s syndrome: The role of magnetic resonance imaging (2004) (84)
- Analysis of gene expression in mutiple sclerosis lesions using cDNA microarrays. (1999) (83)
- Multiple sclerosis: Re‐expression of a developmental gene in chronic lesions correlates with remyelination (1997) (83)
- Intrathecal effects of daclizumab treatment of multiple sclerosis (2011) (83)
- Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease (1997) (82)
- Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. (2003) (82)
- Identification of a novel T cell epitope of human proteolipid protein (residues 40–60) recognized by proliferative and cytolytic CD4+ T cells from multiple sclerosis patients (1993) (82)
- Increased serum levels of soluble CD95 (APO‐1/Fas) in relapsing‐remitting multiple sclerosis (1998) (80)
- Interferon beta results in immediate reduction of contrast‐enhanced MRI lesions in multiple sclerosis patients followed by weekly MRI (1997) (80)
- Immunologic analysis of a spinal cord-biopsy specimen from a patient with human T-cell lymphotropic virus type I-associated neurologic disease. (1997) (80)
- Copolymer-1-induced inhibition of antigen-specific T cell activation: interference with antigen presentation (1992) (79)
- Immunotherapy of multiple sclerosis: Where are we? Where should we go? (2001) (78)
- Study of relapsing remitting experimental allergic encephalomyelitis SJL mouse model using MION‐46L enhanced in vivo MRI: Early histopathological correlation (1998) (77)
- Antiserums to neurons and to oligodendroglia from mammalian brain. (1977) (75)
- Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. (2013) (75)
- Interferon‐β1a therapy in human T‐lymphotropic virus type I–associated neurologic disease (2005) (75)
- Molecular mimicry and antigen-specific T cell responses in multiple sclerosis and chronic CNS Lyme disease. (2001) (74)
- Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency1 (2000) (73)
- VLA-4/CD49d downregulated on primed T lymphocytes during interferon-β therapy in multiple sclerosis (2000) (71)
- Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival. (2000) (71)
- A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule. (1996) (70)
- Serial whole-brain magnetization transfer imaging in patients with relapsing-remitting multiple sclerosis at baseline and during treatment with interferon beta-1b. (1998) (69)
- Reduction in HTLV‐I proviral load and spontaneous lymphoproliferation in HTLV‐I–associated myelopathy/tropical spastic paraparesis patients treated with humanized anti‐tac (1998) (68)
- In vitro studies of cell-mediated immunity in an acute viral infection. (1974) (68)
- Human Autoreactive CD4+ T Cells from Naive CD45RA+ and Memory CD45RO+ Subsets Differ with Respect to Epitope Specificity and Functional Antigen Avidity (2000) (67)
- Effect of open label pulse cyclophosphamide therapy on MRI measures of disease activity in five patients with refractory relapsing–remitting multiple sclerosis (1999) (67)
- T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects (1998) (67)
- Impaired measles virus-specific cytotoxic T cell responses in multiple sclerosis (1985) (67)
- Methylprednisolone effect on brain volume and enhancing lesions in MS before and during IFN&bgr;-1b (2002) (66)
- MRI as a marker for disease heterogeneity in multiple sclerosis (2005) (66)
- Cytokine gene expression in cells derived from CSF of multiple sclerosis patients (1998) (66)
- Age dependence of clinical and pathological manifestations of autoimmune demyelination. Implications for multiple sclerosis. (1999) (65)
- HLA-DR2a is the dominant restriction molecule for the cytotoxic T cell response to myelin basic protein in DR2Dw2 individuals. (1990) (65)
- Identification of an epitope derived from human proteolipid protein that can induce autoreactive CD8+ cytotoxic T lymphocytes restricted by HLA-A3: evidence for cross-reactivity with an environmental microorganism (1997) (63)
- Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals. (1995) (62)
- Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones (1998) (61)
- Complexities in the Treatment of Autoimmune Disease (1996) (61)
- The effect of measles virus infection on T and B lymphocytes in the mouse. I. Suppression of helper cell activity. (1974) (60)
- T cell response to myelin basic protein in the context of the multiple sclerosis-associated HLA-DR15 haplotype: peptide binding, immunodominance and effector functions of T cells (1997) (60)
- Intravenous antigen adrmnistration as a therapy for autoimmune demyelinating disease (1996) (60)
- Elevated serum and cerebrospinal fluid levels of soluble human herpesvirus type 6 cellular receptor, membrane cofactor protein, in patients with multiple sclerosis (2001) (59)
- Myelin basic protein‐specific T‐cell responses in identical twins discordant or concordant for multiple sclerosis (1993) (59)
- Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83–99) (1996) (58)
- The B cell--old player, new position on the team. (2008) (58)
- Induction of subacute murine measles encephalitis by monoclonal antibody to virus haemagglutinin (1981) (56)
- Clinical and pathological features of an autosomal dominant, adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. (1994) (55)
- Familial multiple sclerosis: Clinical, histocompatibility, and viral serological studies (1978) (55)
- Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain. (1988) (55)
- Family and Twin Studies in Multiple Sclerosis (1984) (55)
- The germline repertoire of T-cell receptor beta-chain genes in patients with multiple sclerosis. (1989) (54)
- Kinematic specificity of cortical reorganization associated with motor training (2004) (54)
- Chronic Relapsing Experimental Autoimmune Encephalomyelitis: Effects of Insulin‐like Growth Factor‐I Treatment on Clinical Deficits, Lesion Severity, Glial Responses, and Blood Brain Barrier Defects (1998) (53)
- Time series for modelling counts from a relapsing-remitting disease: application to modelling disease activity in multiple sclerosis. (1994) (53)
- Enhancing magnetic resonance imaging lesions and cerebral atrophy in patients with relapsing multiple sclerosis. (2001) (52)
- Interferon-β interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes (1997) (51)
- Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis. (1994) (50)
- Ring-enhancement in multiple sclerosis: marker of disease severity (2001) (49)
- HPRT mutant T-cell lines from multiple sclerosis patients recognize myelin proteolipid protein peptides (1997) (49)
- Use of magnetic resonance imaging in the diagnosis of multiple sclerosis (1986) (49)
- Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression (2002) (48)
- Unique Clinical and Pathological Features in HLA-DRB1*0401–restricted MBP 111–129–specific Humanized TCR Transgenic Mice (2004) (48)
- Myelin Basic Protein-Specific TCR/HLA-DRB5*01:01 Transgenic Mice Support the Etiologic Role of DRB5*01:01 in Multiple Sclerosis (2012) (47)
- FLAIR and magnetization transfer imaging of patients with post-treatment Lyme disease syndrome (2001) (47)
- Human T‐cell lymphotropic virus type II–associated myelopathy: Clinical and immunologic profiles (1996) (47)
- Computed tomography and magnetic resonance imaging in adult-onset leukodystrophy. (1988) (43)
- Human T-cell response to myelin basic protein peptide (83-99): Extensive heterogeneity in antigen recognition, function, and phenotype (1997) (43)
- Identification of a specific HLA DR2 Ia molecule as a restriction element for measles virus-specific HLA class II-restricted cytotoxic T cell clones (1985) (43)
- Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood—brain barrier disruption in multiple sclerosis (2009) (41)
- Citrulline‐containing myelin basic protein is recognized by T‐cell lines derived from multiple sclerosis patients and healthy individuals (1994) (41)
- Measles virus persistence in human lymphocytes: a role for virus-induced interferon. (1982) (39)
- T cell response to 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in multiple sclerosis patients (2002) (39)
- Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis (2005) (39)
- Selective neuronal, dendritic, and postsynaptic localization of viral antigen in measles-infected mice. (1979) (38)
- Expansion of antigen-specific T cells from cerebrospinal fluid of patients with multiple sclerosis (1983) (37)
- Relationship between inflammatory lesions and cerebral atrophy in multiple sclerosis (2006) (36)
- Multiple sclerosis: Possible immunological mechanisms☆ (1989) (36)
- Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells (1990) (35)
- Magnetic resonance techniques to monitor the long term evolution of multiple sclerosis pathology and to monitor definitive clinical trials. (1998) (34)
- Epitope spreading occurs in active but not passive EAE induced by myelin basic protein (1996) (34)
- Cellular immune response to measles, mumps, and vaccinia viruses in multiple sclerosis (1979) (33)
- Experimental allergic encephalomyelitis induced by the peptide encoded by exon 2 of the MBP gene, a peptide implicated in remyelination (1994) (33)
- Defective interfering particles modulate VSV infection of dissociated neuron cultures (1979) (33)
- 2′,3′-cyclic nucleotide 3′-phosphodiesterase: a novel candidate autoantigen in demyelinating diseases (1997) (32)
- MRI and clinical activity in MS patients after terminating treatment with interferon beta-l b (2000) (32)
- The response of human lymphocyte subpopulations to measles, mumps, and vaccinia viral antigens. (1980) (31)
- Proton MR spectroscopic imaging in multiple sclerosis (2002) (31)
- Extended observations on the association of HHV-6 and multiple sclerosis. (2000) (31)
- Effects of interferon beta-1b on black holes in multiple sclerosis over a 6-year period with monthly evaluations. (2005) (30)
- Correlation of clinical features and findings on cranial magnetic resonance imaging with urinary myelin basic protein‐like material in patients with multiple sclerosis (1994) (29)
- Central nervous system disease in primary Sjogrens syndrome: the role of magnetic resonance imaging. (2004) (29)
- A novel candidate autoantigen in a multiplex family with multiple sclerosis: prevalence of T-lymphocytes specific for an MBP epitope unique to myelination (1993) (29)
- Multiple Sclerosis: A Comprehensive Text (2008) (28)
- T1 cortical hypointensities and their association with cognitive disability in multiple sclerosis (2010) (28)
- Lessons from studies of antigen-specific T cell responses in Multiple Sclerosis. (2000) (28)
- Twin studies and multiple sclerosis (1992) (27)
- The effect of daclizumab on brain atrophy in relapsing-remitting multiple sclerosis. (2013) (27)
- The Role of T Cells in Multiple Sclerosis: Implications for Therapies Targeting the T Cell Receptor (1994) (27)
- Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis. (1994) (27)
- Heterogeneity in response to interferon beta in patients with multiple sclerosis: a 3-year monthly imaging study. (2009) (27)
- Multisequence-imaging protocols to detect cortical lesions of patients with multiple sclerosis: Observations from a post-mortem 3 Tesla imaging study (2009) (26)
- ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions (1998) (26)
- Impaired human leukocyte antigen–restricted measles virus–specific cytotoxic T‐cell response in subacute sclerosing panencephalitis (1989) (25)
- Expression pattern of activation and adhesion molecules on peripheral blood CD4+ T-lymphocytes in relapsing-remitting multiple sclerosis patients: a serial analysis (1996) (25)
- Preliminary trial of poly ICLC in chronic progressive multiple sclerosis (1986) (25)
- Response of human lymphocytes to measles virus after natural infection (1983) (24)
- Measles virus-specific cellular immunity in patients with vaccine failure (1993) (24)
- T-lymphocyte recognition of a portion of myelin basic protein encoded by an exon expressed during myelination (1993) (23)
- Humoral and cellular immune responses to matrix protein of measles virus in subacute sclerosing panencephalitis (1988) (23)
- Diseases Involving Myelin (1999) (23)
- Estimating cerebral atrophy in multiple sclerosis patients from various MR pulse sequences (2002) (23)
- Identification of a second T cell epitore of human proteolipid protein (residues 89–106) recognized by proliferative and cytolytic CD4+ T cells from multiple sclerosis patients (1994) (23)
- CNS vasculitis in a patient with MS on daclizumab monotherapy (2013) (23)
- New cases of progressive multifocal leukoencephalopathy after treatment with natalizumab (2009) (23)
- A functional basis for the association of HLA class II genes adn susceptibility to multiple sclerosis: cellular immune responses to myelin basic protein in a multiplex family (1993) (22)
- CD 4 + CD 28 – costimulation-independent T cells in multiple sclerosis (2001) (22)
- Induction of measles virus-specific human cytotoxic T cells by purified measles virus nucleocapsid and hemagglutinin polypeptides. (1987) (22)
- Differential effects of phosphodiesterase type 4-specific inhibition on human autoreactive myelin-specific T cell clones (1999) (21)
- Chronic measles encephalitis in mice. (1980) (21)
- Antibody-mediated modification of encephalitis induced by hamster neurotropic measles virus. (1983) (21)
- Immunology of Multiple Sclerosis (1988) (20)
- Guidelines for clinical trials of new therapeutic agents in multiple sclerosis: Reporting extended results from phase III clinical trials (1999) (20)
- Adrenergic dysfunction in hereditary adult‐onset leukodystrophy (1987) (19)
- Longitudinal study of myelin basic protein-specific T-cell receptors during the course of multiple sclerosis (1997) (19)
- Oral administration of the nitroxide radical TEMPOL exhibits immunomodulatory and therapeutic properties in multiple sclerosis models (2017) (19)
- Human antiidiotypic antibody against opiate receptors (1988) (18)
- The future of multiple sclerosis therapies: redesigning multiple sclerosis clinical trials in a new therapeutic eraa (2005) (18)
- Cortisol induction by poly ICLC: Implications for clinical trials of interferon (1988) (18)
- T-cell response to myelin basic protein and lipid-bound myelin basic protein in patients with multiple sclerosis and healthy donors (1998) (18)
- Correlation between MR and clinical findings of disease activity in multiple sclerosis. (1999) (17)
- Human T lymphocytes specific for the immunodominant 83–99 epitope of myelin basic protein: Recognition of golli MBP HOG 7 (1996) (17)
- Quality and Quantity of Diffuse and Focal White Matter Disease and Cognitive Disability of Patients with Multiple Sclerosis (2011) (16)
- Subacute sclerosing panencephalitis after passive immunization and natural measles infection (1982) (16)
- Effect of Anti-CD 25 Antibody Daclizumab in the Inhibition of Inflammation and Stabilization of Disease Progression in Multiple Sclerosis (2009) (16)
- Examination of the role of magnetic resonance imaging in multiple sclerosis: A problem-orientated approach (2009) (16)
- Erratum: Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β (Proceedings of the National Academy of Sciences of the United States of America (June 8, 2004) 101:23 (8705-8708)) (2004) (15)
- HLA restriction and TCR usage of T lymphocytes specific for a novel candidate autoantigen, X2 MBP, in multiple sclerosis. (1994) (15)
- Cerebrospinal fluid somatostatin, mood, and cognition in multiple sclerosis (1999) (15)
- Measles virus-polypeptide specificity of the cytotoxic T-lymphocyte response in multiple sclerosis (1989) (15)
- Induction of experimental allergic encephalomyelitis in the NIH minipig (2000) (15)
- Polypeptide specificities of measles virus-reactive T cell lines and clones derived from a patient with multiple sclerosis. (1986) (15)
- THE ROLE OF THE INFLAMMATORY RESPONSE IN VIRAL INFECTIONS (1975) (14)
- Studies of multiple sclerosis in twins (1983) (14)
- Interferon-beta-1b effects on re-enhancing lesions in patients with multiple sclerosis (2005) (13)
- DR2/DQwl Inheritance and haplotype sharing in affected siblings from multiple sclergis families (1996) (13)
- Lymphocytapheresis in chronic progressive multiple sclerosis: Results of a preliminary trial (1983) (13)
- Gene-Marked Autologous Hematopoietic Stem Cell Transplantation of Autoimmune Disease (2004) (13)
- Ring and nodular multiple sclerosis lesions (2010) (13)
- Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis (2000) (12)
- The multiple sclerosis lesion (1995) (12)
- Deficient expression in multiple sclerosis of the inhibitory transcription factor SP3 in mononuclear blood cells (1996) (12)
- Linkage analysis in spinopontine atrophy: correlation of HLA linkage with phenotypic findings in hereditary ataxia. (1987) (11)
- Recognition of Intracellular Measles Virus Antigens by HLA Class II Restricted Measles Virus‐Specific Cytotoxic T Lymphocytes (1988) (11)
- In vivo three-dimensional MR microscopy of mice with chronic relapsing experimental autoimmune encephalomyelitis after treatment with insulin-like growth factor-I. (1998) (11)
- Expression pro ® ling identi ® es responder and non-responder phenotypes to interferon-b in multiple sclerosis (2003) (11)
- Virus‐Specific Cytotoxic T Cells in Multiple Sclerosis (1988) (10)
- Clinical safety of serial monthly administrations of gadopentetate dimeglumine in patients with multiple sclerosis (1997) (10)
- ATTEMPT TO ISOLATE INFECTIOUS AGENT FROM BONE-MARROW OF PATIENTS WITH MULTIPLE SCLEROSIS (1979) (10)
- DR2/DQw1 inheritance and haplotype sharing in affected siblings from multiple sclerosis families. (1996) (10)
- Contrast-enhanced MRI lesions during treatment with interferonβ-1b predict increase in T1 black hole volume in patients with relapsing-remitting multiple sclerosis (2005) (10)
- Effects of viral infection on nervous system development. II. Attempts to modify bluetongue-virus-induced malformations with cyclophosphamide and antithymocyte serum. (1972) (10)
- Lack of over-expression of T cell receptor Vβ5.2 in myelin basic protein-specific T cell lines derived from HLA-DR2 positive multiple sclerosis patients and controls (1998) (9)
- Characterization of antigen-specific T cells in multiple sclerosis twins with elevated proliferative responses to measles virus. (1986) (8)
- National Multiple Sclerosis Society Working Group on Neuroimaging for the Medical Advisory Board (1987) (8)
- Experimental immunotherapies for multiple sclerosis (2004) (8)
- Measles virus-specific human T cell clones: Studies of alloreactivity and antigenic cross-reactivity (1988) (8)
- Impaired Measles‐Specific Cytotoxic T‐Cell Response in Subacute Sclerosing Panencephalitis (1988) (8)
- Immunofluorescent Study of Circulating Antibody in Experimental Allergic Encephalomyelitis 1 (1970) (7)
- MEASLES VIRUS INFECTION OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES: IMPORTANCE OF THE OKT4+ T-CELL SUBSET1 (1984) (7)
- Sjögren's syndrome mimicking multiple sclerosis (1990) (7)
- Contrast-enhanced magnetic resonance activity in relapsing remitting multiple sclerosis patients: a short term natural history study (2000) (7)
- In vitro modulation of human, autoreactive MBP-specific CD4+ T-cell clones by cyclosporin A (1997) (6)
- Immunological Responses to Viruses in Multiple Sclerosis: Cell-mediated Immunity (1982) (6)
- Natalizumab and immune cells. (2006) (6)
- Infection of the central nervous system produced by R1 vesicular stomatitis virus. (1979) (6)
- Acute encephalopathy caused by defective virus infection (1976) (6)
- Monitoring relapsing remitting MS patients (1999) (6)
- Multiple sclerosis: Are HLA class I molecules involved in disease pathogenesis? (1995) (6)
- Characterization of Cerebrospinal Fluid Lymphocytes in Multiple Sclerosis a (1984) (6)
- Multiple sclerosis patients have reduced HLA class II-restricted cytotoxic responses specific for both measles and herpes virus (1991) (5)
- A pilot study of recombinant insulin-like growth factor-I in seven multiple sclerosis patients (2002) (5)
- The path to damage in multiple sclerosis (1999) (5)
- How to participate in a multiple sclerosis clinical trial. (2000) (4)
- Diagnosis of multiple sclerosis. (2008) (4)
- Semi-automatic segmentation and modeling of the cervical spinal cord for volume quantification in multiple sclerosis patients from magnetic resonance images (2008) (4)
- Alemtuzumab versus interferon beta-1a: implications for pathology and trial design (2009) (4)
- Use of magnetic resonance imaging in the diagnosis of multiple sclerosis. Policy statement of the National Multiple Sclerosis Society, New York (1986) (3)
- The effect of interferon beta-1b on size of short-lived enhancing lesions in patients with multiple sclerosis (2008) (3)
- Limited repertoire of HLA-DRB1*0401-restricted MBP111–129-specific T cells in HLA-DRB1*0401 Tg mice and their pathogenic potential (2004) (3)
- Chapter 53 – Multiple Sclerosis (2003) (3)
- Different Development of Myelin Basic Protein Agonist- and Antagonist-Specific Human TCR Transgenic T Cells in the Thymus and Periphery1 (2008) (3)
- Manganese-Enhanced MRI in Patients with Multiple Sclerosis (2020) (3)
- Regulatory T Cells Are Reduced During Anti-CD 25 Antibody Treatment of Multiple Sclerosis (2009) (3)
- Virus-specific cytotoxic T lymphocytes in multiple sclerosis: a normal mumps virus response adds support for a distinct impairment in the measles virus response (1989) (3)
- Neuroimaging and the Use of Magnetic Resonance in Multiple Sclerosis (2001) (3)
- Multiple Sclerosis Therapeutics: The growing need for alternative clinical trial designs for multiple sclerosis (2011) (2)
- Significance of autoreactive T cells in diseases such as multiple sclerosis using an innovative primate model. (1994) (2)
- The Application of Magnetic Resonance Imaging to Phase II Trials in Multiple Sclerosis (1999) (2)
- EXPRESSION OF A NOVEL CANDIDATE AUTOANTIGEN, X2 MBP, IN MULTIPLE SCLEROSIS (MS) LESIONS: 214 (1995) (2)
- T‐cell Receptor Use in Multiple Sclerosis (1995) (2)
- Book Review Multiple Sclerosis as a Neuronal Disease Edited by Stephen G. Waxman. 484 pp., illustrated. San Diego, Calif., Elsevier Academic Press, 2005. $170. 0-12-738761-7 (2005) (2)
- Evaluation of magnetic resonance imaging sensitivity in patients with relapsing remitting multiple sclerosis: baseline versus Betaseron treatment trials. (1996) (2)
- New criteria for the diagnosis of multiple sclerosis (2005) (2)
- The importance of clinical trials in unraveling the mysteries of multiple sclerosis (2011) (2)
- Toxic and Nutritional Disorders of Myelin (1999) (2)
- T‐Cell Receptor α and β CDR3 Expression by Myelin Basic Protein‐Specific Human T‐Cell Clones (1995) (2)
- Correlation with disease severity in multiple sclerosis in CDR3 regions of myelin basic protein-specific T cell receptors (1994) (1)
- EFFECT OF VIRUS INFECTION OF ADULT HUMAN GLIAL CELLS ON EXPRESSION OF HLA MOLECULES: 47 (1989) (1)
- The role of immunological response in infections of the central nervous system. (1974) (1)
- Specificity and Functional Antigen Avidity Subsets Differ with Respect to Epitope + and Memory CD 45 RO + Naive CD 45 RA T Cells from + Human Autoreactive CD 4 (2000) (1)
- Introduction to the Special Issue (2005) (1)
- 65 – Multiple sclerosis (2008) (1)
- Mumps virus-specific cytotoxic T lympocyte responses can be mediated by class II MHC-restricted CD4+ cells (1987) (1)
- DIFFERENTIAL EXPRESSION OF A NOVEL CANDIDATE AUTOANTIGEN, X2 MBP, IN MULTIPLE SCLEROSIS (MS) LESIONS (1996) (1)
- T cell receptor usage in neurological disease: the case in multiple sclerosis (1992) (1)
- From specificity to degeneracy to molecular mimicry: Antigen recognition of human autoreactive and pathogen-specific CD4+ T cells (1998) (1)
- Comment on “Interleukin‐2/Interleukin‐2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation” (2012) (1)
- Examination of the role of MRI in multiple sclerosis: a problem orientated approach. (2010) (1)
- Immune mechanisms relating to viral infections of the nervous system (1988) (1)
- Corrections: Autoreactive CD8^+ T-Cell Responses to Human Myelin Protein- Derived Peptides (1995) (1)
- Clinical neuroimmunology: Multiple sclerosis (1987) (1)
- Multiple Sclerosis Support the Etiologic Role of DRB5*01:01 in TCR/HLA-DRB5*01:01 Transgenic Mice Myelin Basic Protein-Specific (2012) (0)
- Reply (1978) (0)
- Reply (1992) (0)
- Disorders Primarily Affecting Neurons with Secondary Involvement of Myelin (1999) (0)
- Thesis Abstracts 1996 (1996) (0)
- IDENTIFICATION OF INFLAMMATORY FACTORS THAT PROMOTE MYELINATION (2009) (0)
- T-cell receptor alpha and beta CDR3 expression by myelin basic protein-specific human T-cell clones. (1995) (0)
- Relapse May Serve as a Mediator Variable in Longitudinal Outcomes in Multiple Sclerosis (2016) (0)
- Impaired measles-specific cytotoxic T-cell response in SSPE (1987) (0)
- 3D double inversion recovery imaging distinguishes in vivo final stage of chronic black holes in multiple sclerosis patients (2006) (0)
- In vitro inhibition of MBP-specific T cell clones by interferon β (IFN-β) (1996) (0)
- Optic Nerve Cross-Sectional Area Measurement with High-Resolution, Isotropic MRI in Optic Neuritis (P6.159) (2015) (0)
- Detecting multiple sclerosis cortical lesions post-mortem using 7 Tesla Magnetic Resonance Imaging (2009) (0)
- Activation of human class-II restricted T cell clones by short peptides (1998) (0)
- Cerebrospinal Fluid Immunoglobulin Abnormalities in Multiple Sclerosis (1987) (0)
- A MyelinBasicProteinPeptideIsRecognizedby CytotoxicT CellsintheContextofFourHLA DR 'hypesAssociatedwithMultipleSclerosis (1991) (0)
- The Relationship Between Acute Disease Activity on MRI as Reflected by Blood-Brain Barrier Disruption and Clinical Measures of Disease Activity (2000) (0)
- White Holes and Their Impact on Physical Disability in Patients with Multiple Sclerosis (2010) (0)
- Re: GAMES issue. (2004) (0)
- Chronic murine measles encephalitis-a strain depen- dent phenomenon. Abstr. (1979) (0)
- Method for the management of multiple sclerosis (2003) (0)
- Cloned measles virus-specific T lyn multiple sclerosis (2016) (0)
- Brief Definitive Report Identification of a Specific Hla Dr2 Ia Molecule as a Restriction Element for Measles Virus- Specific Hla Class Ii-restricted Cytotoxic T Cell Clones (2003) (0)
- Differential gene expression in multiple sclerosis lesions identified using cDNA microarrays (1998) (0)
- A method for the treatment of multiple sclerosis (2003) (0)
- Immunological Aspects of Multiple Sclerosis with Emphasis on the Potential Use of Autologous Hemopoietic Stem Cell Transplantation (2019) (0)
- New aspects in the treatment of multiple sclerosis with Interferon beta-1b (1997) (0)
- The Clinical and Social Impact of Interferon-β: The First Approved Therapy in Multiple Sclerosis (1999) (0)
- IL-7 modified primary proliferation asa method for generation of antigen-specific T cell lines (TCL) preferentially from the pool of memory T cells (1998) (0)
- Sjogren's syndrome central nervous system disease (SS-CNS) mimicking multiple sclerosis (MS) (1988) (0)
- Measles virus-specific cytotoxic T cell responses to purified measles virus antigens (1985) (0)
- Use-Dependent Plasticity in Patients with Multiple Sclerosis (2004) (0)
- Alternative designs for multiple sclerosis clinical trials (2007) (0)
- Reply from the authors: Ms in twins (1981) (0)
- HIV testing in dialysis units: preventing the plague? (1989) (0)
- FAILURE OF IMMATURE MICE TO DEVELOP CLINICAL SIGNS OF ACUTE EAE CORRELATES WITH APOPTOTIC CLEARANCE OF LYMPHOCYTES FROM THE CNS: 28 (1995) (0)
- Multiple Sclerosis T Cells + High-Avidity Myelin-Specific CD 4 Expansion and Functional Relevance of (2004) (0)
- Platform Presentations (2002) (0)
- I. ADOPTIVE IMMUNIZATION OF IMNrUNOSUPPRESSED MICE [NFECTED WITH SINDBIS VIRUS* (2003) (0)
- Reply (1996) (0)
- Assessment of a “naive” vs “memory” origin of human autoreactive CD4+ T cell clones specific for myelin basic protein (MBP) (1998) (0)
- Pathologic Findings in a Newly Described, Adult‐Onset Leukodystrophy (1990) (0)
- SELECTIVE NEURONAL, DENDRITIC AND POSTSYNAPTIC LOCALIZATION OF VIRAL ANTIGEN IN MEASLES INFECTED INFECTED MICE (1978) (0)
- Acquired Disorders of Myelin (1999) (0)
- to TCR Ligand Potency Within MHC Molecule or Antigenic Peptide Contribution of Individual Amino Acids (1999) (0)
- MS in twins (1981) (0)
- Serum neurofilament light-chain levels and long-term treatment outcomes in relapsing-remitting multiple sclerosis patients: A post hoc analysis of the randomized CombiRx trial (2023) (0)
- Diversity and Function of Human Class II MHC Antigens (1988) (0)
- Oral session 30 — Multiple sclerosis (6) (2005) (0)
- Longitudinal study of T cell receptor usage to myelin basic protein in multiple sclerosis patients (1994) (0)
- Genetic Disorders of Myelin (1999) (0)
- EXPLORING THE RELATIONS BETWEEN EMOTIONAL DISABILITY AND SUBCORTICAL ATROPHY IN PATIENTS WITH MULTIPLE SCLEROSIS (2009) (0)
- Oral session 29 — Multiple sclerosis (5) (2005) (0)
- Postural control and the clinical evaluation of patients with multiple sclerosis (1993) (0)
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