Hergen Spits

Q: What Schools Are Affiliated With Hergen Spits

Hergen Spits is affiliated with the following schools: University of Amsterdam, University of Turin, Kyoto University, Harvard University

Hergen Spits's AcademicInfluence.com Rankings

Hergen Spits

Biology

#5014

World Rank

#7392

Historical Rank

Immunology

#221

World Rank

#230

Historical Rank

biology Degrees

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Biology

Hergen Spits's Degrees

PhD Immunology University of Amsterdam
Doctorate Medicine University of Amsterdam

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Hergen Spits's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Innate lymphoid cells — a proposal for uniform nomenclature (2013) (2061)
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression (1991) (2036)
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy (2006) (1381)
The biology of innate lymphoid cells (2015) (1247)
Innate Lymphoid Cells: 10 Years On (2018) (1139)
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161 (2011) (1060)
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells (2009) (1000)
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. (1997) (971)
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. (1988) (885)
Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues (2013) (855)
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling (2011) (842)
Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus (2013) (687)
Innate lymphoid cells: emerging insights in development, lineage relationships, and function. (2012) (675)
Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells (2009) (663)
Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products. (1986) (594)
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma (2014) (579)
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. (2012) (564)
Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. (1990) (544)
IL-15 trans-presentation promotes human NK cell development and differentiation in vivo (2009) (529)
Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones. (1988) (496)
Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria. (2015) (494)
Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones. (1984) (436)
IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells. (1992) (415)
Human Thymic Stromal Lymphopoietin Preferentially Stimulates Myeloid Cells1 (2001) (410)
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking (2008) (406)
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells☆ (2014) (404)
Development of human T and natural killer cells. (1995) (401)
IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs (2016) (357)
Human innate lymphoid cells. (2016) (357)
Neoantigen landscape dynamics during human melanoma–T cell interactions (2016) (355)
Development of human lymphoid cells. (2006) (340)
NK cells and type 1 innate lymphoid cells: partners in host defense (2016) (334)
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones (1991) (330)
Innate lymphoid cells in inflammation and immunity. (2014) (330)
Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3 (1997) (320)
IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. (1988) (310)
Id2 and Id3 Inhibit Development of Cd34+ Stem Cells into Predendritic Cell (Pre-Dc)2 but Not into Pre-Dc1 (2000) (309)
Functional expression of B7/BB1 on activated T lymphocytes (1993) (300)
Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients. (2014) (284)
Selection of a human T helper type 1-like T cell subset by mycobacteria (1991) (284)
CD40 is functionally expressed on human thymic epithelial cells. (1992) (281)
Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells (2010) (262)
Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon,delta proteins (1992) (262)
A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction (1997) (260)
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation (1992) (258)
Evidence of innate lymphoid cell redundancy in humans (2016) (252)
Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen. (1985) (243)
Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2. (2010) (239)
Recombinant interleukin 4 promotes the growth of human T cells. (1987) (237)
STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation1 (2008) (226)
The developmental relationship between NK cells and T cells. (1992) (221)
Humanized mice for modeling human infectious disease: challenges, progress, and outlook. (2009) (221)
Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. (1999) (219)
Differential effects of IL-4 and IL-10 on IL-2-induced IFN-gamma synthesis and lymphokine-activated killer activity. (1992) (216)
Functional characterization of human IL-10. (1992) (209)
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells. (2004) (208)
Deficiency of a leukocyte surface glycoprotein (LFA-1) in two patients with Mo1 deficiency. Effects of cell activation on Mo1/LFA-1 surface expression in normal and deficient leukocytes. (1984) (208)
CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells. (1996) (202)
Development of αβ T cells in the human thymus (2002) (200)
Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease. (2014) (196)
A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice. (2003) (195)
Early stages in the development of human T, natural killer and thymic dendritic cells (1998) (195)
Molecular Biology of Interleukin 4 and Interleukin 5 Genes and Biology of their Products that Stimulate B Cells, T Cells and Hemopoietic Cells (1988) (193)
The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development (2004) (191)
Experimental Models to Study Development and Function of the Human Immune System In Vivo (2006) (190)
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression (2005) (187)
Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development (1993) (185)
Expression of pTalpha mRNA in a committed dendritic cell precursor in the human thymus. (1999) (181)
Antigen‐specific cytotoxic T cell and antigen‐specific proliferating T cell clones can be induced to cytolytic activity by monoclonal antibodies against T3 (1985) (181)
Immortalization of Human CD8+ T Cell Clones by Ectopic Expression of Telomerase Reverse Transcriptase1 (2000) (179)
Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair? (2009) (178)
IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures. (1988) (175)
Interleukin-4 mediates CDS induction on human CD4+ T-cell clones (1988) (173)
Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo (2011) (173)
HLA‐DC antigens can serve as recognition elements for human cytotoxic T lymphocytes (1984) (169)
Development and activation of regulatory T cells in the human fetus (2005) (164)
Characterization of monoclonal antibodies against cell surface molecules associated with cytotoxic activity of natural and activated killer cells and cloned CTL lines. (1983) (162)
Human innate lymphoid cells. (2014) (160)
High-throughput identification of antigen-specific TCRs by TCR gene capture (2013) (158)
A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. (2002) (155)
Plasticity of innate lymphoid cell subsets (2020) (153)
Biochemical and functional characteristics of the human leukocyte membrane antigen family LFA‐1, Mo‐1 and p!50,95 (1985) (152)
A common solution to group 2 influenza virus neutralization (2013) (151)
Cloned human cytotoxic T lymphocyte (CTL) lines reactive with autologous melanoma cells. I. In vitro generation, isolation, and analysis to phenotype and specificity. (1984) (146)
Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells. (1986) (145)
Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes. (1992) (143)
Generation of stable monoclonal antibody-producing BCR+ human memory B cells by genetic programming (2009) (142)
Development of alphabeta T cells in the human thymus. (2002) (141)
The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. (1996) (139)
The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development. (2003) (137)
Telomerase levels control the lifespan of human T lymphocytes. (2003) (135)
IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis. (2008) (135)
Functional Differences between Human NKp44− and NKp44+ RORC+ Innate Lymphoid Cells (2012) (133)
A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production (1990) (128)
Induction of nonspecific cytotoxicity by monoclonal anti-T3 antibodies. (1985) (125)
Functionally distinct subsets of human γ/δ T cells (1991) (118)
Establishment of human T lymphocyte clones highly cytotoxic for an EBV-transformed B cell line in serum-free medium: isolation of clones that differ in phenotype and specificity. (1982) (118)
T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells (2008) (118)
The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling (2004) (117)
Human natural killer cell committed thymocytes and their relation to the T cell lineage (1993) (116)
Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo. (2002) (115)
CD70 represents the human ligand for CD27. (1994) (114)
Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. (2005) (113)
The low-affinity receptor for IgE (CD23) on B lymphocytes is spatially associated with HLA-DR antigens (1988) (111)
Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR. (1999) (110)
c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies (2019) (110)
Diversity and organization of human T cell receptor delta variable gene segments (1989) (110)
Both Fc receptors and lymphocyte‐function‐associated antigen 1 on human Tγ lymphocytes are required for antibody‐dependent cellular cytotoxicity (killer cell activity) (1984) (109)
Stem Cells into Predendritic Cell (Pre-DC)2 but Not into Pre-DC1: Evidence for a Lymphoid Origin of Pre-DC2 (2000) (109)
Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B. (2006) (107)
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. (2009) (107)
Changing T cell specificity by retroviral T cell receptor display. (2000) (107)
Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis. (2003) (107)
The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens. (1982) (106)
TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation. (1999) (105)
Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q (2011) (104)
Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4. (1990) (103)
Disruption of αβ but not of γδ T cell development by overexpression of the helix–loop–helix protein Id3 in committed T cell progenitors (1999) (99)
IL-6 triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells (2012) (99)
Characterization of melanoma‐associated surface antigens involved in the adhesion and motility of human melanoma cells (1986) (97)
Particle-bound enzymes in the bloodstream form of Trypanosoma brucei. (1977) (93)
Genomic organization of the human T-cell antigen-receptor alpha/delta locus. (1988) (91)
Use of a Novel Chimeric Mouse Model with a Functionally Active Human Immune System To Study Human Immunodeficiency Virus Type 1 Infection (2007) (91)
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia (2014) (90)
Human T4+ and T8+ cytotoxic T lymphocyte clones directed at products of different class II major histocompatibility complex loci. (1983) (90)
Clonal analysis of differential lymphokine production in peptide and superantigen induced T cell anergy. (1991) (90)
Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3. (1999) (89)
IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2−/−IL-2Rγc−/− Mice without Affecting Peripheral T Cell Homeostasis1 (2009) (89)
Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in "human immune system" Rag2(-/-)gammac(-/-) mice. (2006) (88)
Corrigendum: Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming (2016) (88)
Natural killer or dendritic: what's in a name? (2007) (87)
Endogenous IFN-α Production by Plasmacytoid Dendritic Cells Exerts an Antiviral Effect on Thymic HIV-1 Infection1 (2004) (86)
Lymphoid and myeloid differentiation of fetal liver CD34+lineage- cells in human thymic organ culture (1994) (86)
Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells. (1997) (85)
Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells. (1999) (84)
Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development (1993) (83)
Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates (2017) (81)
IL-1, IL-4, and IFN-gamma differentially regulate cytokine production and cell surface molecule expression in cultured human thymic epithelial cells. (1991) (81)
Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response. (2021) (80)
IL-15 transpresentation promotes both human T-cell reconstitution and T-cell–dependent antibody responses in vivo (2011) (80)
Natural killer cell clones can efficiently process and present protein antigens. (1991) (79)
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation (2019) (79)
Developmental stages in the human thymus. (1999) (79)
Complex rearrangements within the human J delta‐C delta/J alpha‐C alpha locus and aberrant recombination between J alpha segments. (1988) (78)
Downregulation of CD1 Marks Acquisition of Functional Maturation of Human Thymocytes and Defines a Control Point in Late Stages of Human T Cell Development (1997) (76)
Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes. (1999) (76)
Interleukin-7 improves T-cell recovery after experimental T-cell-depleted bone marrow transplantation in T-cell-deficient mice by strong expansion of recent thymic emigrants. (2003) (75)
Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis (2015) (75)
Characterization of a third form of the human T cell receptor gamma/delta (1988) (74)
Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression. (2008) (74)
KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3 (2019) (74)
Properties of a panel of monoclonal antibodies which react with the human T cell antigen receptor on the leukemic line HPB-ALL and a subset of normal peripheral blood T lymphocytes. (1986) (73)
Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood (1997) (71)
Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage. (1997) (69)
Antigen recognition by MHC-incompatible cells of a human mismatched chimera (1988) (69)
Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes (2009) (69)
Generation of Human Antigen-Specific Monoclonal IgM Antibodies Using Vaccinated “Human Immune System” Mice (2010) (68)
Thymic stromal lymphopoietin induces early human B‐cell proliferation and differentiation (2010) (68)
Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model (2009) (68)
T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus (2008) (67)
A Novel Mouse Model for Stable Engraftment of a Human Immune System and Human Hepatocytes (2015) (67)
IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter (2009) (67)
Transcriptional control of innate lymphoid cells (2012) (66)
Early stages in human and mouse T-cell development. (1994) (65)
Analysis of cytokine production by Mycobacterium-reactive T cells. Failure to explain Mycobacterium leprae-specific nonresponsiveness of peripheral blood T cells from lepromatous leprosy patients. (1993) (65)
The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells. (2013) (64)
Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice (1999) (64)
TCR Gene Rearrangements and Expression of the Pre-T Cell Receptor Complex During Human T-Cell Differentiation (1999) (64)
Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity (2014) (63)
Distinct signals control the hematopoiesis of lymphoid-related dendritic cells. (2000) (63)
A Distinct Wave of Human T Cell Receptor y / b Lymphocytes in the Early Fetal Thymus : Evidence for Controlled Gene Rearrangement and Cytokine Production (1990) (62)
Identification of a novel human thymocyte subset with a phenotype of CD3- CD4+ CD8 alpha + beta-1. Possible progeny of the CD3- CD4- CD8- subset. (1991) (62)
Quantitative events determine the differentiation and function of helper T cells (2011) (62)
A cloned human T cell line cytotoxic for autologous and allogeneic B lymphoma cells (1984) (62)
Novel Staphylococcal Glycosyltransferases SdgA and SdgB Mediate Immunogenicity and Protection of Virulence-Associated Cell Wall Proteins (2013) (62)
CD2/LFA‐3 or LFA‐l/ICAM‐1 but not CD28/B7 interactions can augment cytotoxicity by virus‐specific CD8+ cytotoxic T lymphocytes (1993) (61)
Human T cell leukemia/lymphoma virus type I infection of a CD4+ proliferative/cytotoxic T cell clone progresses in at least two distinct phases based on changes in function and phenotype of the infected cells. (1989) (61)
Constitutively Active β-Catenin Promotes Expansion of Multipotent Hematopoietic Progenitors in Culture1 (2006) (61)
Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases (2017) (61)
Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156. (1990) (61)
Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection. (2004) (60)
Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors1 (2007) (59)
IL-4 induces LFA-1 and LFA-3 expression on Burkitt's lymphoma cell lines. Requirement of additional activation by phorbol myristate acetate for induction of homotypic cell adhesions. (1989) (56)
SnapShot: innate lymphoid cells. (2013) (55)
Functional and phenotypic differences between CD4+ and CD4- T cell receptor-gamma delta clones from peripheral blood. (1991) (55)
Inducible, Site-Specific Protein Labeling by Tyrosine Oxidation–Strain-Promoted (4 + 2) Cycloaddition (2017) (54)
Innate lymphoid cells in inflammatory bowel diseases. (2016) (54)
New insights into the function, development, and plasticity of type 2 innate lymphoid cells (2018) (53)
Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse. (1991) (53)
Tracing the expression of CD7 and other antigens during T- and myeloid-cell differentiation in the human fetal liver and thymus. (1995) (52)
Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera (1988) (52)
Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2 (2013) (51)
A comparative study of four cytochemical detection methods of concanavalin A binding sites on the cell membrane. (1975) (51)
Flt3 Ligand Expands Lymphoid Progenitors Prior to Recovery of Thymopoiesis and Accelerates T Cell Reconstitution after Bone Marrow Transplantation1 (2007) (50)
Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer. (2002) (50)
APRIL Induces a Novel Subset of IgA+ Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1 (2019) (50)
The role of ILC2 in pathology of type 2 inflammatory diseases. (2014) (49)
NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells. (2000) (49)
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons y and a and prostaglandin E 2 ( IgE regulation / lymphokines / IgE-binding factors / CD 23 ) JMR 6 (49)
A novel Flt3‐deficient HIS mouse model with selective enhancement of human DC development (2016) (48)
Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up (2020) (48)
Type 2 innate lymphoid cells–new members of the “type 2 franchise” that mediate allergic airway inflammation (2012) (47)
IL‐22‐producing CD4+ T cells: Middle‐men between the immune system and its environment (2010) (45)
Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas. (2013) (45)
Human ILC1: To Be or Not to Be (2017) (45)
Human T cell leukemia virus type I prevents cell surface expression of the T cell receptor through down-regulation of the CD3-gamma, -delta, -epsilon, and -zeta genes. (1990) (45)
The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line. (1991) (44)
The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model (2018) (44)
Triggering of cytotoxic T lymphocytes and NK cells via the Tp103 pathway is dependent on the expression of the T cell receptor/CD3 complex. (1988) (44)
Interplay between the TCR/CD3 Complex and CD4 or CD8 in the Activation of Cytotoxic T Lymphocytes (1989) (43)
Human NKp 44 + IL-22 + cells and LTi-like cells constitute a stable RORC + lineage distinct from conventional natural killer cells (2010) (43)
Clonal analysis of human CD4-CD8-CD3- thymocytes highly purified from postnatal thymus. (1991) (43)
Staphylococcal exotoxins deliver activation signals to human T-cell clones via major histocompatibility complex class II molecules. (1991) (43)
Human Telomerase Reverse Transcriptase-Transduced Human Cytotoxic T Cells Suppress the Growth of Human Melanoma in Immunodeficient Mice (2004) (43)
Synergy between IL-15 and Id2 Promotes the Expansion of Human NK Progenitor Cells, Which Can Be Counteracted by the E Protein HEB Required To Drive T Cell Development (2010) (41)
The T-cell receptor gamma chain-CD3 complex: implication in the cytotoxic activity of a CD3+ CD4- CD8- human natural killer clone. (1987) (41)
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) αβ or TcR γδ induce IgE synthesis by human B cells in the presence of interleukin‐4 (1992) (41)
Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1 (2013) (40)
Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T lymphocytes. (1984) (40)
Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases (2021) (40)
Highly efficient gene transfer in naive human T cells with a murine leukemia virus-based vector. (2000) (40)
Th1‐ and Th2‐like subsets of innate lymphoid cells (2013) (38)
Recognition of HLA-A2 by cytotoxic T lymphocytes after DNA transfer into human and murine cells. (1984) (38)
Experimental model for the study of the human immune system: production and monitoring of "human immune system" Rag2-/-gamma c-/- mice. (2008) (38)
Chimerism and tolerance to host and donor in severe combined immunodeficiencies transplanted with fetal liver stem cells. (1993) (38)
A permanent human cytotoxic T-cell line with high killing capacity against a lymphoblastoid B-cell line shows preference for HLA A, B target antigens and lacks spontaneous cytotoxic activity. (1981) (38)
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis (2020) (38)
Human thymus regeneration and T cell reconstitution. (2007) (38)
Stable long‐term cultures of self‐renewing B cells and their applications (2016) (38)
Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance (2016) (37)
Stimulated plasmacytoid dendritic cells impair human T-cell development. (2006) (36)
In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells. (1994) (35)
Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors. (1999) (35)
The modified FACS calcein AM retention assay: A high throughput flow cytometer based method to measure cytotoxicity. (2016) (34)
Comparative analysis of CD8 expressed on mature CD4+ CD8+ T cell clones cultured with IL-4 and that on CD8+ T cell clones: implication for functional significance of CD8 beta. (1991) (34)
Reactivity of cloned, expressed human FcγRIII isoforms with monoclonal antibodies which distinguish cell-type-specific and allelic forms of FcγRIII (1990) (33)
Human CD5+ Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34+ Progenitor Cells Is Regulated by Id2 (2017) (33)
The role of T8 in the cytotoxic activity of cloned cytotoxic T lymphocyte lines specific for class II and class I major histocompatibility complex antigens. (1985) (33)
Evidence for a regulatory role of the T8 (CD8) antigen in antigen‐specific and anti‐T3‐(CD3)‐induced lytic activity of allospecific cytotoxic T lymphocyte clones (1986) (32)
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation (2020) (32)
T cell precursors in man and mice. (1998) (32)
Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens (2019) (31)
Complex rearrangements within thehuman J- CI/J.- Calocus andaberrant recombination between J.segments (1988) (31)
A combination of anti-CD3 and anti-CD7 ricin A-immunotoxins for the in vivo treatment of acute graft versus host disease. (2000) (31)
Critical assessment of human antibody generation in humanized mouse models. (2014) (31)
Antigen specific and MHC nonrestricted cytotoxicity of T cell receptor alpha beta+ and gamma delta+ human T cell clones isolated in IL-4. (1989) (30)
Expression of the major histocompatibility antigens HLA-A2 and HLA-B7 by DNA-mediated gene transfer. (1983) (30)
Complexity of T cell receptor recognition sites for defined alloantigens. (1987) (29)
Expansion of Interleukin‐22– and Granulocyte–Macrophage Colony‐Stimulating Factor–Expressing, but Not Interleukin‐17A–Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis (2019) (29)
Innate lymphoid cells: from helper to killer. (2020) (29)
T cell clones which share T cell receptor epitopes differ in phenotype, function and specificity (1986) (28)
Developmental origin of pre-DC2. (2002) (28)
Genetic manipulation of B cells for the isolation of rare therapeutic antibodies from the human repertoire. (2014) (28)
CD40 expressed on thymic epithelial cells provides costimulation for proliferation but not for apoptosis of human thymocytes. (1996) (28)
Use of bicistronic retroviral vectors encoding the LacZ gene together with a gene of interest: a method to select producer cells and follow transduced target cells. (1996) (28)
The role of the T cell receptor, CD8, and LFA-1 in different stages of the cytolytic reaction mediated by alloreactive T lymphocyte clones. (1987) (27)
Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development. (1993) (27)
Regulation by anti-CD2 monoclonal antibody of the activation of a human T cell clone induced by anti-CD3 or anti-T cell receptor antibodies. (1987) (26)
Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs (2020) (26)
Induction of phenotypic differentiation, interleukin 2 production, and PHA responsiveness of "immature" human thymocytes by interleukin 1 and phorbol ester. (1983) (26)
Functionally distinct subsets of human gamma/delta T cells. (1991) (25)
Innate Lymphoid Cells (ILCs): Cytokine Hubs Regulating Immunity and Tissue Homeostasis. (2018) (24)
Untransfected and SV40-transfected fetal and postnatal human thymic stromal cells. Analysis of phenotype, cytokine gene expression and cytokine production. (1993) (24)
Comparison of target antigens of monoclonal reagents OKT5, OKT8, and Leu2A, which inhibit effector function of human cytotoxic T lymphocytes. (1983) (24)
Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming (vol 16, pg 123, 2010) (2010) (23)
Generation and Characterization of Anti–Citrullinated Protein Antibody–Producing B Cell Clones From Rheumatoid Arthritis Patients (2019) (23)
Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance. (2019) (23)
The replacement of monocytes and interleukin-1 by phorbol ester in lectin-induced proliferation of human thymocytes and T cells. (1982) (22)
In vivo modulation of gene expression by lentiviral transduction in "human immune system" Rag2-/- gamma c -/- mice. (2010) (22)
Human fetal liver-derived CD7+CD2lowCD3-CD56- clones that express CD3 gamma, delta, and epsilon and proliferate in response to interleukin-2 (IL-2), IL-3, IL-4, or IL-7: implications for the relationship between T and natural killer cells. (1992) (21)
A family of T-cell receptor molecules expressed on T-cell clones with different specificities for allomajor histocompatibility antigens. (1986) (21)
Coexpression of the human HLA-A2 or HLA-B7 heavy chain gene and human beta 2-microglobulin gene in L cells. (1984) (21)
HLA Class‐II‐restricted Mycobacterium lepraereactive T‐Cell Clones from Leprosy Patients Established with a Minimal Requirement for Autologous Mononuclear Cells (1986) (20)
Introduction of T cell receptor (TCR)-alpha cDNA has differential effects on TCR-gamma delta/CD3 expression by PEER and Lyon-1 cells. (1989) (20)
Generation and Maintenance of Cloned Human T Cell Lines (2005) (20)
Reciprocal hybrid joints demonstrate successive V-J rearrangements on the same chromosome in the human TCR gamma locus. (1991) (19)
Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease. (2019) (19)
Patient-derived antibody recognizes a unique CD43 epitope expressed on all AML and has antileukemia activity in mice. (2017) (19)
Accelerated thymopoiesis and improved T‐cell responses in HLA‐A2/‐DR2 transgenic BRGS‐based human immune system mice (2019) (19)
Autonomous and extrinsic regulation of thymopoiesis inhuman immune system (HIS) mice (2011) (18)
CD4 is involved in a post-binding event in the cytolytic reaction mediated by human CD4+ cytotoxic T lymphocyte clones. (1988) (18)
Comparison of lymphokine secretion and responsiveness of human T cell clones isolated in IL-4 and in IL-2. (1991) (18)
Heterogeneity of type 2 innate lymphoid cells (2022) (18)
A cloned cytotoxic T-lymphocyte (CTL) line recognizing a subtype of HLA B27. (1984) (18)
Preparation of bispecific antibody-protein adducts by site-specific chemo-enzymatic conjugation. (2019) (17)
Isolation of Human Innate Lymphoid Cells (2018) (17)
Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells (2021) (17)
Development of retrovirally marked human T progenitor cells into mature thymocytes. (1995) (17)
Do human TH1 and TH2 CD4+ clones exist? (1991) (16)
Stimulation through CD50 (ICAM-3) induces both activation and programmed cell death of human thymocytes. (1996) (16)
Identification of human cytotoxic ILC3s (2020) (16)
Presence of Host‐Reactive and MHC‐Restricted T Cells in a Transplanted Severe Combined Immunodeficient (SCID) Patient Suggest Positive Selection and Absence of Clonal Deletion (1990) (16)
A novel beta 4, alpha 6 integrin-associated epithelial cell antigen involved in natural killer cell and antigen-specific cytotoxic T lymphocyte cytotoxicity (1991) (16)
CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease (2021) (16)
CD 34 + CD 38 dim Cells in the Human Thymus Can Differentiate Into T , Natural Killer , and Dendritic Cells But Are Distinct From Pluripotent Stem Cells (2002) (15)
Ontogeny of Human Natural Killer (NK) Cells: Fetal NK Cells Mediate Cytolytic Function and Express Cytoplasmic CD3e,~ Proteins (2003) (15)
AML-specific cytotoxic antibodies in patients with durable graft-versus-leukemia responses. (2018) (15)
Production of IL4 by human T cells and regulation of differentiation of T-cell subsets by IL4. (1993) (15)
Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies (2015) (14)
The Role of the Common Gamma Chain of the IL-2, IL-4, IL-7 and IL-15 Receptors in Development of Lymphocytes. Constitutive Expression of Bcl-2 does not Rescue the Developmental Defects in Gamma Common-Deficient Mice (1997) (14)
Stem Cell Factor Consistently Improves Thymopoiesis after Experimental Transplantation of Murine or Human Hematopoietic Stem Cells in Immunodeficient Mice (2011) (14)
A chemo-enzymatically linked bispecific antibody retargets T cells to a sialylated epitope on CD43 in acute myeloid leukemia. (2019) (13)
Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria. (1990) (13)
Antigen-specific, but not natural killer, activity of T cell receptor-gamma delta cytotoxic T lymphocyte clones involves secretion of N alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine esterase and influx of Ca2+ ions. (1989) (12)
Functional Expression of B7/BB1 on Activated (1993) (12)
IL-4: Structure and Function (1992) (12)
Differential recognition by human cytotoxic T cell clones of human M1 fibroblasts transfected with an HLA-B7 gene (JY150) suggests the existence of two different HLA-B7 alleles in the cell line JY (HLA-A2,2;B7,7;Cw-,-;DR4,w6). (1988) (12)
Innate lymphoid cells: The missing part of a puzzle in food allergy (2020) (12)
Distribution and functional analysis of a 120- to 130-kDa T-cell surface antigen. (1987) (12)
In vitro-isolated human cytotoxic T-lymphocyte clones detect variations in serologically defined HLA antigens (2004) (11)
Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition (2016) (11)
Human T cell receptor gamma delta + T cells. (1991) (11)
BOB.1 controls memory B-cell fate in the germinal center reaction. (2019) (10)
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4. (1992) (10)
Isolation of human thymocytes differing in maturation state and function by centrifugal elutriation. (1982) (10)
Polymorphisms within the HLA-DRw6 haplotype. I. Restriction fragment length variation and its correlation with serology. (1985) (10)
Reactivity of cloned, expressed human Fc gamma RIII isoforms with monoclonal antibodies which distinguish cell-type-specific and allelic forms of Fc gamma RIII. (1990) (10)
Polymorphism of Human Fc-Receptors for Mouse Igg1 and Igg2b (1985) (10)
PJA-BP expression and TCR delta deletion during human T cell differentiation. (1998) (9)
The Transcriptional Coactivator Bob1 Is Associated With Pathologic B Cell Responses in Autoimmune Tissue Inflammation (2017) (9)
Human T cell lines differing in phenotype and specificity are reactive with the same anti-idiotypic antibody. (1986) (9)
Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit. (2014) (9)
A SCID patient reconstituted with HLA-incompatible fetal stem cells as a model for studying transplantation tolerance. (1991) (8)
REGULATION OF HUMAN NK ACTIVITY AGAINST ADHERENT TUMOR TARGET CELLS BY MONOCYTE SUBPOPULATIONS, INTERLEUKIN-1, AND INTERFERONS (1982) (8)
PIM1 Reconstitutes Thymus Cellularity in Interleukin 7– and Common (cid:103) Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not CD3 (cid:103) -deﬁcient Mice (1999) (8)
Interleukin‐33 improves local immunity during Gram‐negative pneumonia by a combined effect on neutrophils and inflammatory monocytes (2020) (8)
Group 2 innate lymphoid cells show up in the skin (2013) (8)
Regulation of M-CSF production by cultured human thymic epithelial cells. (1993) (8)
AML relapse after rituximab treatment for GvHD: crucial role for B cells in GvL responses (2016) (7)
AB0049 Human Type 1 Innate Lymphoid Cells Accumulate in the Inflamed Synovium in Spondyloarthritis (2015) (7)
Differentiation to Control Human Plasma Cell Is Coordinated with BCL 6 Down-Regulation STAT 3-Mediated Up-Regulation of BLIMP 1 (2008) (7)
Therapeutic potential of genetically modified T-lymphocytes in Crohn's disease (2000) (7)
Reclassifying plasmacytoid dendritic cells as innate lymphocytes (2022) (7)
The role of Ca2+ and Mg2+ in the cytotoxic T lymphocyte reaction and in the secretion of N alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester-serine esterase by human T cell clones. (1989) (7)
Isolation and in vitro generation of gene-manipulated human plasmacytoid and conventional dendritic cells. (2010) (7)
T lymphocytes from human chimeras do recognize antigen in the context of allogeneic determinants of the major histocompatibility complex. (1993) (6)
The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut. (2012) (6)
T cell receptor‐dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity (2000) (6)
CD45RA+CD62L− ILCs in human tissues represent a quiescent local reservoir for the generation of differentiated ILCs (2022) (6)
Analysis of antigen specificity of human TCR gamma delta + T cells. (1990) (6)
Correction: Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma (2016) (6)
Another armament in gut immunity: lymphotoxin-mediated crosstalk between innate lymphoid and dendritic cells. (2011) (6)
The cell-mediated lympholysis-inducing capacity of highly purified human monocytes and T lymphocytes in primary and secondary mixed leukocyte cultures. (1981) (6)
Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo (2020) (5)
Multiplex flow cytometry-based assay to study the breadth of antibody responses against E1E2 glycoproteins of hepatitis C virus. (2017) (5)
Phosphoinositide 3-kinase (PI3K) and nutrient sensing mTOR (mammalian target of rapamycin) pathways control T lymphocyte trafficking (2011) (5)
TOX sets the stage for innate lymphoid cells (2015) (5)
New models of human immunity (2014) (5)
Identification of human pre-T/NK cell-associated genes. (1993) (5)
Antigen-Specific Monoclonal Antibodies Isolated from B Cells Expressing Constitutively Active STAT5 (2011) (5)
The T cell receptor/T3 complex. (1986) (4)
A combination of anti-CD 3 and anti-CD 7 ricin A-immunotoxins for the in vivo treatment of acute graft versus host disease (4)
CHARACTERIZATION OF A THIRD FORM OF THE HUMAN T CELL RECEPTOR y/S (2003) (4)
Correction: KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3 (2019) (4)
Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1. (2013) (4)
Techniques for studying development of human natural killer cells and T cells. (2000) (4)
γδ T cells in coeliac disease. Discussion (1990) (3)
PJA-BP expression and T cell receptor-δ (TCRD) deletion during human T cell differentiation (1997) (3)
Heterogeneity of HLA-B7 as Detected by Cytotoxic T Cell Clones (1984) (3)
Characterization of CD34+ thymic stromal cells located in the subcapsular cortex of the human thymus. (1998) (3)
Cloning, expression, and crystallization of the Vδ domain of a human γδ T‐cell receptor (1996) (3)
Innate immunity — phagocytes, natural killer cells and the complement system (2005) (3)
Human IL23R R381Q Genetic Variant Implicated in Crohn's Disease Pathogenesis is Hypomorphic Resulting in Reduced Function of the Receptor (2011) (3)
Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3. (1991) (3)
Immunomodulation following vaccination with autologous, GM-CSF transduced and irradiated tumor cells in patients with advanced melanoma (1997) (2)
Author Correction: c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies (2019) (2)
Testing for HLA/peptide tetramer-binding to the T cell receptor complex on human T lymphocytes. (2012) (2)
IL-7-mediated protection against minor-antigen-mismatched allograft rejection is associated with enhanced recovery of regulatory T cells. (2007) (2)
AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia (2019) (2)
Altered Frequencies and Functions of Innate Lymphoid Cells in Melanoma Patients Are Modulated by Immune Checkpoints Inhibitors (2022) (2)
Modeling human lung infections in mice (2019) (2)
Tolerance to Alloantigens and Recognition for “Allo + X” Induced in Humans by Fetal Stem Cell Transplantation (1994) (2)
GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation (2022) (2)
Target antigen of monoclonal reagent S5.7: comparison with T3 antigen. (1983) (2)
Immunotherapy for Upper Airway Disease Generates IL-10-Producing KLRG1 + ILC2s that are Associated with Clinical Benefit (2020) (1)
582P Preclinical development of AT1412, a patient derived CD9 antibody that does not induce thrombosis for treatment of precursor B ALL (2020) (1)
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice (2022) (1)
Early events in human intrathymic T-cell development. (1994) (1)
580P AT1412, a patient-derived CD9 antibody promotes tumour immune infiltration and induces tumour rejection (2020) (1)
A2.13 Phenotypic and Molecular Profile of Innate Lymphoid Cells in Chronic Synovial Inflammation (2013) (1)
Tumor Specific Glycosylated CD43 Is a Novel and Highly Specific Target for Acute Myeloid Leukemia and Myelodysplastic Syndrome (2016) (1)
Structural and functional aspects of the T-cell differentiation antigens T3, T6, and T8. (1983) (1)
Regulatory role of the CD8 antigen in both CD3 and CD2 monoclonal antibody‐induced nonspecific cytotoxicity of class I‐ and class II‐allospecific cytotoxic T cell clones (1988) (1)
bHLH transcription factors play a critical role in T cell development (1997) (1)
PROPERTIES OF A PANEL OF MONOCLONAL ANTIBODIES WHICH REACT WITH THE HUMAN T CELL ANTIGEN RECEPTOR ON THE LEUKEMIC LINE T LYMPHOCYTES' HPB-ALL AND A SUBSET OF NORMAL PERIPHERAL BLOOD (1986) (1)
CD34+ Thy-1+ thymic stromal cells are located in the subcapsular cortex of the human thymus (1997) (1)
The role of ILC subsets in cancer. (2022) (1)
Preferentially Stimulates Myeloid Cells Human Thymic Stromal Lymphopoietin (2012) (1)
PS971 AT1413 ANTIBODY DERIVED FROM A CURED AML PATIENT RECOGNIZES A UNIQUE CD43 EPITOPE SHARED BY AML, MDS AND MELANOMA AND HAS IN VIVO ACTIVITY AS UNMODIFIED ANTIBODY AND AS BISPECIFIC T CELL ENGAGER (2019) (1)
Donor-Derived B Cells Produce Potent AML-Specific Antibodies That Recognize Novel Tumor-Specific Antigens and Mediate Graft-Versus-Leukemia Immunity (2015) (1)
14 A patient derived antibody targeting the tetraspanin CD9 inhibits tumour progression and metastasis (2018) (1)
Corrigendum: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking (2008) (1)
A new edge to immune surveillance by the neural system (2016) (1)
Acceleration and Enhancement of T-Cell Recovery and Immune Competence by Flt3-Ligand (Flt3L) Following BMT with Low Numbers of Progenitor Cells in Immune Deficient Mice. (2004) (1)
susceptibility to graft-versus-host disease Activated innate lymphoid cells are associated with a reduced (2014) (1)
Human T-Cell Biology in a Mouse Environment (2014) (1)
Neuropilin-1 flags lung-resident type 2 innate lymphoid cells (2022) (1)
Characterization of triple negative clones isolated from post-natal human thymus. (1991) (1)
Role of human innate lymphoid cells in IMID (2012) (1)
Tumour-reactive B cells and antibody responses after allogeneic haematopoietic cell transplantation (2020) (1)
Abstract A026: Tumor-specific glycosylated CD43 is a novel and highly specific target for acute myeloid leukemia and myelodysplastic syndrome (2016) (1)
Progenitors in Culture Expansion of Multipotent Hematopoietic -Catenin Promotes b Constitutively Active (2006) (1)
Author Correction: c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies (2019) (0)
Vaccination with GM-CSF transduced melanoma cells: A promising treatment (1997) (0)
Plasticity of innate lymphoid cell subsets (2020) (0)
Preclinical Development of AT1412, a Patient Derived CD9 Antibody That Does Not Induce Thrombosis for Treatment of B ALL (2020) (0)
Karakterisering van antigeen specificiteiten en biologische responsen van CD4+ melanoom-specifieke T cellen. (1999) (0)
Peripheral T Cell Homeostasis Mice without Affecting - / - c g IL-2R - / - Rag2 Development in ''Human Immune System'' IL-7 Enhances Thymic Human T Cell (2009) (0)
Effective Inhibition of Bone Morphogenetic ProteinFunctionbyHighlySpeci fi cLlama-Derived Antibodies (2015) (0)
and Spi-B dendritic cell versus T-cell lineage decision through control of GATA-3 Delta-like1-induced Notch1 signaling regulates the human plasmacytoid (2012) (0)
Tissue-Specific Functions of Innate Lymphoid Cells 1. Development and Heterogeneity of Innate Lymphoid Cells (2013) (0)
Characterization of antigen specificities and biological responses of CD4+ melanoma specific T cells. (1999) (0)
998 Immunotherapy with autologous, irradiated melanoma cells transduced with the GM-CSF gene (1995) (0)
The role of interleukin 10 in immunosuppression of tumor responses. (1999) (0)
OP0200 Circulating, Auto-Reactive B Cells Specific for Citrullinated Antigens in Patients with Rheumatoid Arthritis Display An Activated, Proliferative Phenotype (2016) (0)
The role of Bob1 in rheumatoid arthritis: potential implications for autoimmunity (2012) (0)
Abstract LB-200: A patient derived antibody targeting the tetraspanin CD9 synergistically inhibits tumor growth with an anti PD1 antibody (2017) (0)
An antibody derived from a cured AML patient to identify a unique epitope on CD43 (CD43s) as a novel target for acute myeloid leukemia and myelodysplastic syndrome. (2017) (0)
PO-436 Retargeting T-cell cytotoxicity to a unique sialylated epitope on CD43 expressed by acute myeloid leukaemia (2018) (0)
Experimental timeframe and analysis of human hepatocyte engraftment in HUHEP and HIS-HUHEP mice. (2015) (0)
Author response for "Accelerated thymopoiesis and improved T cell responses in HLA‐A2/‐DR2 transgenic BRGS‐based human immune system mice" (2019) (0)
Abstract A061: Acute myeloid leukemia patients cured after allogeneic hematopoietic stem cell transplantation generate tumor-specific cytotoxic antibodies that kill AML blasts (2016) (0)
Faculty Opinions recommendation of Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. (2003) (0)
Induction and Enhancement of Lymphokine Gene Expression in Human T Cell Clones Transfected with HTLV-I pX cDNA (1988) (0)
Anticorps anti-cd9 thérapeutique (2017) (0)
expansion of recent thymic emigrants bone marrow transplantation in T-cell-deficient mice by strong Interleukin-7 improves T-cell recovery after experimental T-cell-depleted (2013) (0)
AML Relapse after Rituximab Treatment for Graft-Versus-Host Disease: Crucial Role for B Cells in Graft-Versus-Host and Graft-Versus-Leukemia (2015) (0)
CHAPTER 2 – Dendritic cells in the thymus (2001) (0)
stem cells natural killer, and dendritic cells but are distinct from pluripotent CD34+CD38dim cells in the human thymus can differentiate into T, (2011) (0)
Marrow Transplantation Accelerates T Cell Reconstitution after Bone Prior to Recovery of Thymopoiesis and Flt3 Ligand Expands Lymphoid Progenitors (2007) (0)
stress-induced apoptosis and regulatory T cell clones and confers resistance to oxidative Ectopic hTERT expression extends the life span of human CD4+ helper (2013) (0)
Cell Reconstitution after Bone Prior to Recovery of Thymopoiesis and Flt 3 Ligand Expands Lymphoid Progenitors (2007) (0)
Dispositifs et procédé de production d'anticorps à haute affinité (2011) (0)
cell precursors in vivo Intrathymic and extrathymic development of human plasmacytoid dendritic (2013) (0)
Reconstitution of Innate Lymphoid Cells After Hematopoietic Stem Cell Transplantation (2012) (0)
HTLV-I Infection of a Human Antigen Specific Proliferating/Cytotoxic T Cell Clone Results in a Loss of Cytotoxicity but does not Affect the T Cell Receptor (1988) (0)
In Vivo and Function of the Human Immune System Experimental Models to Study Development (2006) (0)
Crystal structure of CD9 large extracellular loop (2020) (0)
Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs (2020) (0)
Evidence of innate lymphoid cell redundancy in humans (2016) (0)
double-mutant mice-/-c γ-/-transfer of human peripheral blood mononuclear cells in RAG 2 A new xenograft model for graft-versus-host disease by intravenous (2003) (0)
35TH FORUM IN IMMUNOLOGY - DISCUSSION (1991) (0)
Evidence for controlled gene rearrangements and cytokine production during development of human TCR gamma delta+ lymphocytes. (1991) (0)
HUMAN T CELL LINES DIFFERING IN REACTIVE WITH THE SAME PHENOTYPE AND SPECIFICITY ARE ANTI-IDIOTYPIC ANTIBODY' (1986) (0)
Cell Surface Determinants Associated with the Interaction of Human CTL Clones and Autologous Tumor Cells (1985) (0)
Generation of human tumor specific T cells with high affinity T cell receptors (2008) (0)
The Loss of PTEN Allows TCR (cid:1)(cid:2) Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling (2004) (0)
Procedure for generating and proliferating cell lines that differ (2002) (0)
McLellan Respiratory Syncytial Virus Structure-Based Design of a Fusion Glycoprotein Vaccine for (2014) (0)
Unique and Potent Tumor Specific Antibodies in Graft Versus Leukemia Responses (2014) (0)
Reply to ‘Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature’ (2023) (0)
cells Distinct signals control the hematopoiesis of lymphoid-related dendritic (2013) (0)
Preclinical test of a lentivirus-mediated RNAi gene therapy against HIV-AIDS in the humanized mouse model (2011) (0)
Down-Regulatory Role of CD8 Molecules in CD2 MAb and CD3 MAb Induced Nonspecific Cytotoxicity of Cytotoxic T Lymphocyte Clones (1989) (0)
PO-402 Establishment of human monoclonal anti tumour antibodies with high affinity to CD9 using an in vitro B cell affinity maturation platform (2018) (0)
Crystal structure of AT1412dm Fab fragment (2021) (0)
Changes in cytotoxic precursorT cell frequencies after vaccination with GM-CSF-transduced, autologous melanoma cells: 493 (1997) (0)
THE STABILITY OF CELLS (2017) (0)
The use of interleukin-10 analogs or antagonists for the treatment of endotoxin-induced toxicity taisuperantigeenin (1994) (0)
Abstract B052: Donor derived cytotoxic antibodies from transplanted AML patients targeting a cell surface expressed nuclear antigen (2016) (0)
Cytokine accelerated T-cell recovery after allogeneic stem cell transplantation: experimental studies in mice with an emphasis on IL-7 (2002) (0)
435 Human group 2 innate lymphoid cells differentiate into interleukin-17A producing cells in psoriasis (2019) (0)
Production of MAGE-3 positive APC using a retroviral vector for the stimulation of TCR transduced T cells. (1998) (0)
CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease (2021) (0)
Mouse to man (SY5-5) Chairpersons: Kazuhiko Yamamoto, Riitta Lahesmaa (2010) (0)
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation (2019) (0)
Stem Cell Factor (SCF) Improves Thymopoiesis After Experimental Hematopoietic Stem Cell Transplantation In Both a Murine BMT Model and In “human Immune system” (HIS) Mice, Receiving a Human Stem Cell Graft. (2010) (0)
Role of human innate lymphoid cells in IMID (2012) (0)
Suitability of a cocktail of CD3 and CD7 ricin A-immunotoxins for in vivo treatment of acute graft-versus-host-disease (1997) (0)
Antigen receptors in lymphoid cell development and lymphocyte activation. (1998) (0)
Erratum to: 'Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance' (J Hepatol 2019; 71(1): 14-24). (2020) (0)
Abstract 542: T-cell engager bispecific formats of an AML patient-derived antibody targeting a unique sialylated CD43 epitope induce kill of melanoma cellsin vitroandin vivo (2020) (0)
721 AT1412, a patient-derived CD9 antibody in preclinical development promoting tumor immune infiltration and inducing tumor rejection (2020) (0)
Abstract 531: AT1412, a patient-derived antibody in development for the treatment of CD9-positive precursor B-acute lymphoblastic leukemia (2020) (0)
Lymphocyte development. (2013) (0)
A Novel B4,ce6 htegrin-associated Epithelial Cell Antigen Involved in Natural Killer Cell and Antigen-specific Cytotoxic T Lymphocyte Cytotoxicity (2003) (0)
Human reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient (2008) (0)
A Dual Function of the T4 Molecule in the Cytolytic Activity of Human T Cell Clones (1988) (0)
Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites (1993) (0)
Regulation of cellular life span of antigen-specific T cells and application of immortalized CTL for therapy of melanoma (2002) (0)
Issue Information (2021) (0)
Modulation of Lymphonkine Activated Killer Activity of Lymphocytes Isolated from Human Peripheral Blood and Bone Marrow by Recombinant IL4 (1988) (0)
PO-434 AT1413 antibody derived from a cured AML patient recognisesa unique sialylated CD43 epitope shared by AML, MDS and melanoma cells (2018) (0)
In search of T-cell progenitors in the human foetal liver. (1994) (0)
OP0239 Phenotypic and Molecular Profile of Innate Lymphoid Cells in Chronic Synovial Inflammation (2013) (0)
Changes in cytotoxic precursor T cell frequencies after vaccination with GM-CSF-transduced, autologous melanoma cells (1997) (0)
Author response for "Identification of human cytotoxic ILC3s" (2020) (0)
Establishment of diagnostic and therapeutic monoclonal anti tumor antibodies from B cells of cancer patients (2010) (0)
Tpa mimics Interleukin-1 in the induction of mitogen responsiveness and maturation of immature human thymocytes (1981) (0)
Rsv-specific binding molecules and means for preparation thereof (2008) (0)
Progenitors Receptor Transfer into Hematopoietic Produced In Vitro Using Retroviral T Cell Functional Human Antigen-Specific T Cells (2007) (0)
NK cell cytotoxicity mediated by CD40 and CD80 recognition (1997) (0)
c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies (2019) (0)
ID: 172: Role of innate lymphoid cells in pathology of type 2 inflammatory diseases (2015) (0)
The role of Bob1 in rheumatoid arthritis: potential implications for autoimmunity (2012) (0)
Abstract 532: A patient-derived anti-CD9 antibody induces tumor rejection and synergistically enhances anti-PD1 activity (2020) (0)
Mechanisms of allergen-specific B cell tolerance in children with cow’s milk-oral immunotherapy and natural outgrowth of milk allergy (2021) (0)
Human lymphoid tissue inducer (LTi) cells are CD127+RORc+ and can be expanded ex vivo (91.11) (2009) (0)
GAMMA DELTA T CELLS IN COELIAC DISEASE. DISCUSSION (1990) (0)
SAT0021 Innate lymphoid cells are not a main source of il-17a in the inflamed spondyloarthritis joint (2018) (0)
Means and methods to influence the stability of antibody producing cells (2006) (0)
Required To Drive T Cell Development Which Can Be Counteracted by the E Protein Expansion of Human NK Progenitor Cells , Synergy between IL-15 and Id 2 Promotes the Yasuda (2010) (0)
Cloning, expression, and crystallization of the VS domain of a human y6 T-cell receptor (1996) (0)
The induction of T cell-mediated cytolysis by monoclonal antibodies against the T cell receptor/CD3 complex. (1989) (0)
Faculty Opinions recommendation of Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. (2004) (0)
313 IL-17A–producing type 3 innate lymphoid cells derive from type 2 innate lymphoid cells (2017) (0)
UvA-DARE ( Digital Academic Repository ) Antigen-Specific Monoclonal Antibodies Isolated from B Cells Expressing Constitutively Active STAT 5 (2011) (0)
Abstract PR11: Neo-antigen landscape dynamics during human melanoma-T cell interactions (2016) (0)
Human NaturalKillerCellCommitted Thymocytes and TheirRelationtotheT CellLineage (1993) (0)
Means and procedures to influence the stability of the antibody producing cells (2006) (0)
and XBP-1 expression Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 (2013) (0)
A Novel Human Effector B cell Subset (2017) (0)
that activated STAT5 is required for Hodgkin lymphomagenesis IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence (2008) (0)
PJA-BP expression and TCR δ deletion during human T cell differentiation (1998) (0)
Abstract 5163: A colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin (2020) (0)
P035 The transcriptional co-activator bob.1 prevents terminal differentiation and induces costimulatory capacity of B cells in GC-like environment (2018) (0)
development Stimulated plasmacytoid dendritic cells impair human T-cell (2013) (0)
OP0205 April induces a novel subset of iga+ regulatory b cells that suppress inflammation through the expression of il-10 and pd-l1 (2018) (0)
499 AT1636, a colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin (2020) (0)
New Insights in Development and Function of Human Innate Lymphoid Cells (2012) (0)
The Road from Mouse to Human ILCs: A Perspective of Understanding the Roles of ILCs in Disease. (2022) (0)
myeloid-cell development fetal liver and thymus: CD7 expression in the early stages of T- and Phenotypic and functional analysis of T-cell precursors in the human (2011) (0)
A5.31 The Role of BOB1 in Rheumnatoid Arthritis: Potential Implications for Autoimmunity (2013) (0)

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