Hermann Koepsell
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Engineering Computer Science
Hermann Koepsell's Degrees
- Masters Electrical Engineering Stanford University
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Hermann Koepsell's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cloning and expression of a rat brain L-glutamate transporter (1992) (1213)
- Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications (2007) (957)
- Drug excretion mediated by a new prototype of polyspecific transporter (1994) (654)
- Cloning and characterization of two human polyspecific organic cation transporters. (1997) (637)
- Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion (2011) (545)
- The SLC22 drug transporter family (2004) (504)
- Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. (2005) (413)
- SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. (2014) (394)
- Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. (2010) (382)
- Maintenance of Serotonin in the Intestinal Mucosa and Ganglia of Mice that Lack the High-Affinity Serotonin Transporter: Abnormal Intestinal Motility and the Expression of Cation Transporters (2001) (374)
- Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver (2009) (348)
- Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy. (2011) (347)
- The SLC22 family with transporters of organic cations, anions and zwitterions. (2013) (344)
- Organic cation transporters in intestine, kidney, liver, and brain. (1998) (331)
- The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin (2009) (326)
- Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. (1998) (319)
- The Role of SGLT1 and GLUT2 in Intestinal Glucose Transport and Sensing (2014) (314)
- Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. (2013) (312)
- A glucose sensor hiding in a family of transporters (2003) (309)
- Drug specificity and intestinal membrane localization of human organic cation transporters (OCT). (2005) (247)
- Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene (2001) (238)
- Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences. (2002) (224)
- Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. (2014) (223)
- Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. (2005) (222)
- Drug uptake systems in liver and kidney. (2003) (222)
- Electrogenic Properties and Substrate Specificity of the Polyspecific Rat Cation Transporter rOCT1* (1996) (221)
- Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (2014) (207)
- Organic cation transporters. (2003) (199)
- Localization of organic cation transporters OCT1 and OCT2 in rat kidney. (2000) (199)
- Polyspecific organic cation transporters: their functions and interactions with drugs. (2004) (199)
- Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion (2012) (192)
- Functional expression of sodium-glucose transporters in cancer (2015) (182)
- Glucose transporters in brain in health and disease (2020) (171)
- SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy (2017) (171)
- A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters (2005) (166)
- Molecular Pharmacology of Organic Cation Transporters in Kidney (1999) (159)
- Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. (2012) (150)
- DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma (2011) (147)
- Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody. (2008) (144)
- Acetylcholine and molecular components of its synthesis and release machinery in the urothelium. (2007) (142)
- Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. (2001) (138)
- Amino Acids Critical for Substrate Affinity of Rat Organic Cation Transporter 1 Line the Substrate Binding Region in a Model Derived from the Tertiary Structure of Lactose Permease (2005) (134)
- Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells. (2002) (133)
- Organic Cation Transporters in Health and Disease (2020) (132)
- Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3 (2009) (128)
- Membrane localization of the electrogenic cation transporter rOCT1 in rat liver. (1998) (121)
- Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. (1999) (120)
- Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (117)
- The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation. (2000) (117)
- Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1 (1996) (116)
- Reaction of monoclonal antibodies with plasma membrane proteins after binding on nitrocellulose: renaturation of antigenic sites and reduction of nonspecific antibody binding. (1987) (116)
- Expression of the Na+‐d‐Glucose Cotransporter SGLT1 in Neurons (1997) (109)
- Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus (2016) (108)
- Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter. (1993) (107)
- Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. (2001) (101)
- Subtype-Specific Affinity for Corticosterone of Rat Organic Cation Transporters rOCT1 and rOCT2 Depends on Three Amino Acids within the Substrate Binding Region (2005) (101)
- Organic cation transporter capable of transporting serotonin is up‐regulated in serotonin transporter‐deficient mice (2003) (98)
- A Reevaluation of Substrate Specificity of the Rat Cation Transporter rOCT1* (1997) (98)
- Mechanism of Electrogenic Cation Transport by the Cloned Organic Cation Transporter 2 from Rat* (2000) (97)
- Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases. (2003) (92)
- Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation. (2005) (89)
- The Na+‐D‐glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer (2017) (82)
- Regulation of the human organic cation transporter hOCT1 (2004) (82)
- Glucose transporters in the small intestine in health and disease (2020) (81)
- Role of organic cation transporters in drug–drug interaction (2015) (79)
- Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse (2006) (78)
- Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2. (2003) (77)
- The structural organization of the mouse kidney (2004) (77)
- The position of short and long loops of Henle in the rat kidney (2004) (77)
- The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26. (1997) (75)
- Transport of the new chemotherapeutic agent beta-D-glucosylisophosphoramide mustard (D-19575) into tumor cells is mediated by the Na+-D-glucose cotransporter SAAT1. (1998) (74)
- ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. (2009) (73)
- SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1. (2019) (72)
- Substrate recognition and translocation by polyspecific organic cation transporters (2011) (70)
- Characterization of regulatory mechanisms and states of human organic cation transporter 2. (2006) (70)
- Localization of the Na+-d-glucose cotransporter SGLT1 in the blood-brain barrier (2004) (70)
- Drug uptake transporters in antiretroviral therapy. (2011) (70)
- The Large Extracellular Loop of Organic Cation Transporter 1 Influences Substrate Affinity and Is Pivotal for Oligomerization* (2011) (70)
- Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. (2009) (69)
- Down‐regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis (2004) (68)
- INHIBITION OF OAT3-MEDIATED RENAL UPTAKE AS A MECHANISM FOR DRUG-DRUG INTERACTION BETWEEN FEXOFENADINE AND PROBENECID (2006) (67)
- Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. (2007) (66)
- Cell free expression and functional reconstitution of eukaryotic drug transporters. (2008) (65)
- Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1) (2013) (61)
- Mice without the Regulator Gene Rsc1A1 Exhibit Increased Na+-d-Glucose Cotransport in Small Intestine and Develop Obesity (2005) (60)
- Cloning and expression of a rat brain L-glutamate transporter (1992) (59)
- Osmotic diuresis by SGLT2 inhibition stimulates vasopressin‐induced water reabsorption to maintain body fluid volume (2020) (59)
- Sodium‐glucose co‐transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes (2017) (58)
- Five Amino Acids in the Innermost Cavity of the Substrate Binding Cleft of Organic Cation Transporter 1 Interact with Extracellular and Intracellular Corticosterone (2009) (58)
- Human Organic Cation Transporter 1 Is Expressed in Lymphoma Cells and Increases Susceptibility to Irinotecan and Paclitaxel (2012) (58)
- High-Affinity Cation Binding to Organic Cation Transporter 1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modeled Interaction Domain between Two Helices (2008) (57)
- Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice (2016) (56)
- Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule. (2009) (55)
- The impact of high-fat diet on metabolism and immune defense in small intestine mucosa. (2015) (54)
- Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart (2017) (52)
- Transport of small organic cations in the rat liver (1996) (52)
- Role of the renal sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats (2015) (49)
- The Organic Cation Transporters rOCT1 and hOCT2 Are Inhibited by cGMP (2002) (49)
- RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1. (2006) (48)
- Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia. (2019) (48)
- Alkali Cation Binding and Permeation in the Rat Organic Cation Transporter rOCT2* (2005) (47)
- Rat renal glucose transporter SGLT1 exhibits zonal distribution and androgen-dependent gender differences. (2006) (47)
- Downregulation of the Na+-D-glucose Cotransporter SGLT1 by Protein RS1 (RSC1A1) is Dependent on Dynamin and Protein Kinase C (2003) (47)
- A Renal Olfactory Receptor Aids in Kidney Glucose Handling (2016) (47)
- The Cation Transporters rOCT1 and rOCT2 Interact with Bicarbonate but Play Only a Minor Role for Amantadine Uptake into Rat Renal Proximal Tubules (2002) (47)
- Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+. (2013) (45)
- Reconstitution and partial purification of several Na+ cotransport systems from renal brush-border membranes. Properties of the L-glutamate transporter in proteoliposomes. (1984) (44)
- SGLT1 sugar transporter/sensor is required for post-oral glucose appetition. (2016) (41)
- An improved method for real-time monitoring of membrane capacitance in Xenopus laevis oocytes. (2002) (41)
- 3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3 (2007) (40)
- Measurements of exponential gradients of sodium and chlorine in the rat kidney medulla using the electron microprobe (2004) (40)
- Purification and functional reconstitution of the rat organic cation transporter OCT1. (2005) (39)
- Sucrose- and H+-Dependent Charge Movements Associated with the Gating of Sucrose Transporter ZmSUT1 (2010) (39)
- Mechanistic aspects of the cytotoxic activity of glufosfamide, a new tumour therapeutic agent (2000) (39)
- Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. (2018) (38)
- Methodological aspects of purification and reconstitution of transport proteins from mammalian plasma membranes. (1986) (37)
- A Substrate Binding Hinge Domain Is Critical for Transport-related Structural Changes of Organic Cation Transporter 1* (2012) (35)
- Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent (2009) (35)
- Chronic Pressure Overload Induces Cardiac Hypertrophy and Fibrosis via Increases in SGLT1 and IL-18 Gene Expression in Mice. (2018) (34)
- Addition of NMDA-receptor antagonist MK801 during oxygen/glucose deprivation moderately attenuates the upregulation of glucose uptake after subsequent reoxygenation in brain endothelial cells (2012) (34)
- Duodenal-Jejunal Bypass Improves Glycemia and Decreases SGLT1-Mediated Glucose Absorption in Rats With Streptozotocin-Induced Type 2 Diabetes (2013) (34)
- Partial purification and reconstitution of the Na+-D-glucose cotransport protein from pig renal proximal tubules. (1983) (34)
- Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat. (2018) (34)
- Na(+)-D-glucose cotransporter in muscle capillaries increases glucose permeability. (2004) (34)
- The Plasma Membrane-associated Protein RS1 Decreases Transcription of the Transporter SGLT1 in Confluent LLC-PK1 Cells* (2001) (34)
- Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus. (2006) (34)
- Tripeptides of RS1 (RSC1A1) Inhibit a Monosaccharide-dependent Exocytotic Pathway of Na+-d-Glucose Cotransporter SGLT1 with High Affinity* (2007) (33)
- Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters. (2003) (33)
- Multiple binding sites in organic cation transporters require sophisticated procedures to identify interactions of novel drugs (2018) (33)
- Expression profiling and immunolocalization of Na+-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats (2017) (32)
- Voltage and substrate dependence of the inverse transport mode of the rabbit Na+/glucose cotransporter (SGLT1) (2000) (30)
- Electron microscopic immunohistochemical localization of components of Na+-cotransporters along the rat nephron. (1989) (30)
- Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse (2007) (30)
- Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug–drug interactions (2015) (29)
- Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron. (2016) (29)
- Cloning and characterization of the transport modifier RS1 from rabbit which was previously assumed to be specific for Na+-D-glucose cotransport. (1999) (28)
- The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium (2012) (28)
- The human gene of a protein that modifies Na(+)-D-glucose co-transport. (1996) (28)
- Targeting of sodium-glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han:SPRD rats. (2013) (28)
- Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity. (2007) (27)
- Structure and Function of Renal Organic Cation Transporters. (1998) (27)
- Knockout of Na-glucose-cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase-1 in macula densa and glomerular hyperfiltration (2019) (27)
- Characterization and histochemical localization of the rat intestinal Na(+)-D-glucose cotransporter by monoclonal antibodies. (1990) (27)
- Liver X receptor-activating ligands modulate renal and intestinal sodium-phosphate transporters. (2011) (26)
- Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion. (2019) (25)
- Pattern of luminal diameter changes along the descending and ascending thin limbs of the loop of Henle in the inner medullary zone of the rat kidney (2004) (25)
- The transport modifier RS1 is localized at the inner side of the plasma membrane and changes membrane capacitance. (2000) (25)
- Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression. (2003) (25)
- Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy (2017) (24)
- Comparison of a Na+/D-glucose cotransporter from rat intestine expressed in oocytes of Xenopus laevis with the endogenous cotransporter. (1991) (24)
- A simple liposomal system to reconstitute and assay highly efficient Na+/D-glucose cotransport from kidney brush-border membranes. (1983) (24)
- Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice (2015) (24)
- Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine. (2009) (24)
- Rat Organic Cation Transporter 1 Contains Three Binding Sites for Substrate 1-Methyl-4-phenylpyridinium per Monomer (2018) (24)
- Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model. (2019) (24)
- Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA‐methyltransferase inhibitors (2014) (23)
- Polyspecific organic cation transporters and their biomedical relevance in kidney (2013) (23)
- Monoclonal antibodies against the renal Na+-D-glucose cotransporter. Identification of antigenic polypeptides and demonstration of functional coupling of different Na+-cotransport systems. (1988) (22)
- Phosphorylation of RS1 (RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption (2016) (22)
- Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced in vitro testing (2021) (22)
- The Würzburg Anatomical Institute and its supply of corpses (1933-1945). (2012) (21)
- Different classes of nucleotide binding sites in the (Na+ + K+)-ATPase studied by affinity labeling and nucleotide-dependent SH-group modifications. (1982) (20)
- Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine uptake and cytotoxicity in chronic lymphocytic leukemia (CLL) cells (2015) (20)
- Cyclosporin binding to a protein component of the renal Na(+)-D-glucose cotransporter. (1990) (18)
- Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake (2018) (18)
- Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1 (2020) (18)
- Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions (2016) (17)
- Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin. (2018) (17)
- SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice (2017) (17)
- Absolute protein quantification allows differentiation of cell‐specific metabolic routes and functions (2015) (17)
- Endogenous L-glutamate transport in oocytes of Xenopus laevis. (1991) (17)
- A monoclonal antibody against a Na(+)-L-glutamate cotransporter from rat brain. (1992) (16)
- Nitric oxide-induced regulation of renal organic cation transport after renal ischemia-reperfusion injury. (2011) (16)
- Identification of the D‐glucose binding polypeptide of the renal Na+‐D‐glucose cotransporter with a covalently binding D‐glucose analog (1985) (15)
- General Overview of Organic Cation Transporters in Brain. (2021) (15)
- Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions (2017) (15)
- RECONSTITUTION OF D‐GLUCOSE TRANSPORT AND HIGH‐AFFINITY PHLORIZIN BINDING AFTER SOLUBILIZATION OF KIDNEY BRUSH BORDER PROTEINS (1980) (15)
- Function and presumed molecular structure of Na+-D-glucose cotransport systems (1994) (15)
- Reconstitution and fractionation of renal brush border transport proteins. (1990) (15)
- Channels in planar bilayers made from commercially available lipids (1984) (15)
- Identification of D-glucose-binding polypeptides which are components of the renal Na+-D-glucose cotransporter. (1987) (14)
- Novel Shuttling Domain in a Regulator (RSC1A1) of Transporter SGLT1 Steers Cell Cycle‐Dependent Nuclear Location (2009) (14)
- Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes (2016) (14)
- Role of the Transporter Regulator Protein (RS1) in the Modulation of Concentrative Nucleoside Transporters (CNTs) in Epithelia (2012) (14)
- Structure and function of the sodium and potassium-coupled glutamate transporter from rat brain. (1993) (13)
- Identification of an Mr 75000 component of the H+/D-glucose cotransporter from Zea mays with monoclonal antibodies directed against the mammalian Na+/D-glucose cotransporter. (1989) (12)
- Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity? (2014) (12)
- Synthesis of 18F-fluoroalkyl-beta-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters. (2003) (12)
- New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans. (2021) (11)
- RS 1 ( RSC 1 A 1 ) regulates the exocytotic pathway of Na-D-glucose cotransporter SGLT 1 (2006) (11)
- Ileal Interposition in Rats with Experimental Type 2 Like Diabetes Improves Glycemic Control Independently of Glucose Absorption (2015) (11)
- Polyspecific cation transporters in the proximal tubule. (2000) (11)
- Two substrate sites in the renal Na+-d-glucose cotransporter studied by model analysis of phlorizin binding and-d-glucose transport measurements (1990) (10)
- Analysis of Na+-D-glucose cotransporter and other renal brush border proteins in human urine. (1991) (10)
- Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis (2014) (9)
- Interaction of phlorizin with the Na+―D-glucose cotransporter from intestine and kidney (1987) (9)
- Protein kinase C–dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells (2009) (9)
- Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet (2018) (8)
- PHOTOAFFINITY LABELING OF MEMBRANE PROTEINS FROM RAT LIVER AND PIG KIDNEY WITH CYCLOSPORINE DIAZIRINE (1988) (8)
- RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury (2018) (8)
- Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase (2016) (8)
- In vivo two-photon fluorescence microscopy opens a new area for investigation of the excretion of cationic drugs in the kidney. (2007) (7)
- Characteristics of antibody inhibition of rat kidney (Na+−K+)-ATPase (1978) (6)
- Giant MDCK cells: a novel expression system. (1990) (5)
- SGLT1 participates in the development of vascular cognitive impairment in a mouse model of small vessel disease (2020) (5)
- Erratum: Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (5)
- Response to Comment on: Gorboulev et al. Na+-d-glucose Cotransporter SGLT1 Is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion. Diabetes 2012;61:187–196 (2012) (5)
- A special issue on glucose transporters in health and disease (2020) (5)
- Response to “Tenofovir Disoproxil Fumarate Is Not an Inhibitor of Human Organic Cation Transporter 1” (2017) (5)
- Oxidative stress and Na+-glucose cotransporters Sglt1 and Sglt2 in kidneys of ochratoxin A-treated rats (2011) (4)
- Role of the macula densa sodium glucose cotransporter type 1-nitric oxide synthase 1-tubuloglomerular feedback pathway in diabetic hyperfiltration. (2021) (4)
- Sequence analysis of the catalytic subunit of H(+)-ATPase from porcine renal brush-border membranes. (1992) (4)
- Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD (2018) (4)
- An analysis of biphasic time courses: the inactivation of (Na+ + K+)-ATPase and Ca2+-ATPase by ATP-analogs. (1983) (4)
- Erratum to the report of the third international workshop on human Y chromosome mapping 1997 (1997) (4)
- Absence of the Na‐Glucose Cotransporter SGLT1 Ameliorates Kidney Recovery in a Murine Model of Acute Kidney Injury (2018) (3)
- Conformational changes of membrane-bound (Na+−K+)-ATPase as revealed by antibody inhibition (1979) (3)
- A Modified Tripeptide Motif of RS1 (RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose (2018) (3)
- Measurement of Na K ATPase activity in segments of proximal tubules from superficial and juxtamedullary rat nephrons during antidiuresis (1976) (3)
- SGLT 2 and SGLT 1 renal expression in patients with type 2 diabetes (2017) (3)
- Roct1, a rat polyspecific transporter gene for the excretion of cationic drugs, maps to Chromosome 1q11-12 (1996) (3)
- Characterization of p-aminohippurate transport from rat kidney which is expressed after injection of size-selected mRNA into oocytes of Xenopus laevis. (1993) (2)
- Organic Anion and Cation Transporters in Renal Elimination of Drugs (2013) (2)
- What makes SGLT2 inhibition so effective in lowering blood glucose in diabetes? (689.5) (2014) (2)
- Organic Cation and Zwitterion Transporters (OCTs, OCTNs) (2014) (2)
- Antidiabetic Effects of a Tripeptide That Decreases Abundance of Na+-d-glucose Cotransporter SGLT1 in the Brush-Border Membrane of the Small Intestine (2020) (2)
- Conformational changes of membrane-bound (Na+−K+)-ATPase as revealed by trypsin digestion (1979) (2)
- Structure of Na+-D-Glucose Cotransport Systems (1994) (2)
- Functional Properties of Organic Cation Transporter OCT1, Binding of Substrates and Inhibitors, and Presumed Transport Mechanism (2016) (2)
- High-affinity Cation Binding to Transporter OCT 1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modelled Interaction Domain between Two Helices (2007) (2)
- Contribution of SGLT1 in cardiac glucose uptake (2018) (1)
- Molecular pharmacology of organic cation transport (2000) (1)
- A radioimmunoassay to screen for antibodies to native conformational antigens and analyse ligand-induced structural states of antigenic proteins. (1988) (1)
- The SGLT2 Inhibitor, Empagliflozin, Attenuates Some Markers of Renal Fibrosis without Improving Albuminuria in Diabetic Db/Db Mice (2016) (1)
- Assignment of the membrane-associated modulator of the Na(+)-sugar cotransport systems gene RSC1A1 to human chromosome 1p36.1 by in situ hybridization. (1996) (1)
- Monoclonal antibodies against luminal membranes of renal proximal tubules which are kidney-specific. (1993) (1)
- CHAPTER 73 – Organic Anion and Cation Transporters in Renal Elimination of Drugs (2008) (1)
- Attempts to purify the renal Na+-D-glucose cotransport protein (1985) (1)
- Plenary Lectures, Oral Sessions, Poster Sessions and Symposia (2002) (1)
- Substructure of membrane-bound Na+−K+-ATPase protein (1979) (1)
- Immunological characterization of Na+ and K+ mediated structural states of rat kidney Na+-k+-ATPase. (1977) (1)
- 907 - Deficits in Apical Sodium and Water Transporters Along with Maintenance of CFTR Account for Diarrheal Pathology in MYO5B Ko Mice and Patients with MVID (2018) (1)
- Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes (2023) (1)
- Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis (2014) (1)
- No extrarenal expression of SGLT2 and sex differences in renal expression (2012) (1)
- Real-time monitoring of plasma membrane dynamics in Xenopus oocytes using a simple and robust method to measure capacitance (2001) (0)
- Immunodetection of Na+-D-glucose cotransporters hSGLT1 and hSGLT2 in human organs (2008) (0)
- by PKA, PI3K, and calmodulin-dependent kinases Regulation of human organic cation transporter hOCT2 (2016) (0)
- Functional expression of human organic cation transporter 3 in renal cancer cells (2008) (0)
- SFB 35 tranSmembrane tranSporterS In HeaLtH and dISeaSe (2010) (0)
- Contents, Vol. 4, 1994 (1994) (0)
- Salvia fruticosa tea drinking reduces the expression of sodium/glucose cotransporter 1 in enterocytes brush-border membrane of streptozotocin-induced diabetic rats (2007) (0)
- Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (2014) (0)
- A08 Deficiency in Sodium-Dependent Glucose Transporter 1 has no Effect on Brain Edema Formation after Traumatic Brain Injury (2012) (0)
- OCT-2, Organic Cation Transporter 2 (2008) (0)
- SODIUM-D-GLUCOSE COTRANSPORTER SGLT1 (SLC5A1) IN MOUSE (2013) (0)
- 3 2 DRUG UPTAKE SYSTEMS IN LIVER AND KIDNEY (2001) (0)
- Hepatocellular uptake of organic cations by the organic anion transporting polypeptides (Oatp1, Oatp2 and OATP-A) and the organic cation transporters (rOCT1 and hOCT1) (2000) (0)
- Cancer Therapy : Preclinical Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 ( OCT 1 ) (2014) (0)
- Gender differences in rat renal Na+-glucose cotransporter SGLT1 (2005) (0)
- The binding of drugs to organic cation transporters and their translocation across the plasma membrane (2005) (0)
- Expression profiling and immunolocalization of Na+-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats (2017) (0)
- [Cortico-medullary water distribution in rat kidneys during anti- and water-diuresis]. (1976) (0)
- Already published in CDM) Drug Uptake Systems in Liver and Kidney (2004) (0)
- differences and androgen-dependent gender Rat renal glucose transporter SGLT1 exhibits zonal (2006) (0)
- Leptin mediates downregulation of intestinal SGLT1 and hyperplasia in obese type 2 diabetic mice (2016) (0)
- Interaction of antihypertensives and antibiotics with hepatic (hOCT1) and renal (hOCT2) human organic cation transporters (2006) (0)
- OCTN-2, Organic Cation-Sodium Transporter 2 (2008) (0)
- Expression of sodium-D-glucose cotranspotre SGLT1 (SLC5A1) in murine organs (2013) (0)
- OCT-3, Organic Cation Transporter 3 (2008) (0)
- TripeptidesofRS1(RSC1A1)InhibitaMonosaccharide-dependent Exocytotic Pathway of Na-D-Glucose Cotransporter SGLT1 (2007) (0)
- Chapter 2 Functional Properties of Organic Cation Transporter OCT 1 , Binding of Substrates and Inhibitors , and Presumed Transport Mechanism (2017) (0)
- Subject Index, Vol. 79, 1997 (1997) (0)
- antibody SGLT1 in rat organs with an improved Revised immunolocalization of the Na+-D-glucose (2008) (0)
- Brush-border and basolateral transporters of organic compounds in acute and subchronic models of experimental cadmium nephrotoxicity in rats (2013) (0)
- Transport of mutagenic vital dye ethidium bromide by the human organic cation transporters hOCT2 and hOCT3 (2008) (0)
- Design of Nanohydrogels for Targeted Intracellular Drug Transport to the Trans-Golgi Network. (2023) (0)
- 26 Obstructive cholestasis results in down-regulation and functional impairment of the organic cation transporter 1 (OCT1) in rat (2003) (0)
- Proximal Tubular Transport of Organic Compounds Polyspecific cation transporters in the proximal tubule (2000) (0)
- The A BC o f S olute C arriers (2004) (0)
- G-protein coupled receptors for succinate (GPR91)and alpha ketoglutarate (GPR99) are differently localized in the human and mouse nephron (2007) (0)
- Contribution of SGLT1 in cardiac glucose transport (2019) (0)
- IDENTIFICATION OF COMPONENTS OF NA+-D-GLUCOSE COTRANSPORT PROTEINS IN BRUSH-BORDER MEMBRANES FROM RENAL CORTEX (1987) (0)
- Monoclonal Antibodies against the Renal Na +-D-Glucose Cotransporter IDENTIFICATION OF ANTIGENIC POLYPEPTIDES AND DEMONSTRATION OF FUNCTIONAL COUPLING OF (2001) (0)
- Impaired Regulation of Renal K Elimination in Mice Lacking SGLT1 (2012) (0)
- Na+-glucose co-transporter SGLT2 in rat kidney (2007) (0)
- Regulation of the Na +-D-glucose cotransporter SGLT 1 in small intestine in response to bariatric surgery and peptides derived from protein RS 1 ( RSC 1 A 1 ) (2015) (0)
- Knockout of Na‐glucose transporter SGLT1 lowers GFR and kidney weight in non‐diabetic and Akita diabetic mice (2016) (0)
- Lack of SGLT1 enhances renal oxidative stress, reduces kidney weight, and blunts diabetic glomerular hyperfiltration (2011) (0)
- Urinary excretion of renal tubular cell proteins after cisplatinum therapy (1993) (0)
- Age-related expression of organic compound and water transporters in rat kidneys (2013) (0)
- Will inhibitors of glucose transport in the diabetes therapy act specifically in the kidneys (2015) (0)
- Abstract 885: Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine cytotoxic action. (2013) (0)
- Subject Index, Vol. 4, 1994 (1994) (0)
- Membrane transporters of organic compounds in experimental cadmium nephrotoxicity (2012) (0)
- Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg (1990) (0)
- Subject Index, Vol. 73, 1996 (1996) (0)
- [Electron probe microanalysis determination of the corticomedullary gradient of sodium and chlorine in the rat kidney]. (1974) (0)
- Inhibitors of glucose transporter SGLT1 in the treatment of diabetes mellitus will not act only in the kidneys ; the transporter is also present in other rodent and human organs (2015) (0)
- Contents, Vol. 79, 1997 (1997) (0)
- A Single Dose of Oral Metformin Reduces the Post-Prandial Glucose Response Through a Transient Modulation of Apical Sodium-Glucose Co-Transporter (2019) (0)
- Structurally Different Nucleotide Binding Sites in Na,K-ATPase (1983) (0)
- The human organic cation transporter 2 (hOCT2) transports cadmium (Cd2+) and mediates Cd2+ induced cell death (2008) (0)
- Evaluation of the Influence of Biosurface Design on the Interaction between the Regulatory Peptide RS1‐reg and ODC1 Reveals a Membrane‐Dependent Affinity Increase (2022) (0)
- Leptin but not its long form receptor regulates intestinal membrane expression of sodium/glucose transporter‐1 and intestinal hyperplasia (2013) (0)
- Deficits in Enterocyte Apical Transporters Associated with Loss of Myosin VB (2017) (0)
- Transport proteins that determines the transport of xenobiotics and / or cationic drugs, DNA sequences encoding same and its use. (1995) (0)
- Evidence for three atp binding sites in the (Na+ + K+)-ATPase (1979) (0)
- MEMBRANE TRANSPORTERS IN EXPERIMENTAL CADMIUM NEPHROTOXICITY (2012) (0)
- Potential Harmful Effects of The Novel Anti-Diabetics, Inhibitors of Sodium-Glucose Cotransporters SGLT1 and SGLT2 (2016) (0)
- CELLULAR LOCALIZATION AND SEX-RELATED PROTEIN EXPRESSION OF ORGANIC CATION TRANSPORTERS OCT1 AND OCT2 IN MOUSE KIDNEYS AND LIVER (2014) (0)
- Interaction of drugs at organic cation transporters in the plasma membrane: Mechanistics, risks and benefits (2013) (0)
- Renal Olfactory Receptor 1393 Contributes to the Progression of Diabetes (2018) (0)
- Sodium-glucose cotransporter Sglt1 (Slc5a1) is present in various murine organs : sex-related expression in kidneys (2015) (0)
- Gender and species differences in the mammalian organic cation transporters (2010) (0)
- Acute kidney injury - Experimental models (2011) (0)
- Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity (2007) (0)
- Immunochemical characterization of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidneys, small intestine and liver (2009) (0)
- Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy (2017) (0)
- Transcriptional and post-transcriptional regulation of SGLT1 by RS1 (2005) (0)
- Renal expression and localization of sodium-d-glucose cotransporter 1 (SGLT1) is different in rats and mice (2012) (0)
- EXPRESSION OF SODIUM-D-GLUCOSE COTRANSPORTER 1 IN MURINE TISSUES ; SEX-DEPENDENT EXPRESSION IN KIDNEYS (2014) (0)
- Indications of several nucleotide binding sites on the Na+ -K+-ATPase molecule. (1980) (0)
- Species differences in the expression of sodium-D-glucose cotransporter 1 (SGLT1/SLC5A1), a potential therapeutic target in diabetes (2016) (0)
- OCT-1, Organic Cation Transporter 1 (2008) (0)
- Immunolocalization of the Na+-Glucose Cotransporter SGLT1 in Male and Female Rats with an Improved Antibody (2007) (0)
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