Hermann Koepsell

Q: What Schools Are Affiliated With Hermann Koepsell

Hermann Koepsell is affiliated with the following schools: University of California, Berkeley, Stanford University, University of Würzburg

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Hermann Koepsell

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Hermann Koepsell

Computer Science

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Engineering
Computer Science

Hermann Koepsell's Degrees

Masters Electrical Engineering Stanford University
Bachelors Computer Engineering University of California, Berkeley

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Hermann Koepsell's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cloning and expression of a rat brain L-glutamate transporter (1992) (1213)
Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications (2007) (957)
Drug excretion mediated by a new prototype of polyspecific transporter (1994) (654)
Cloning and characterization of two human polyspecific organic cation transporters. (1997) (637)
Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion (2011) (545)
The SLC22 drug transporter family (2004) (504)
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. (2005) (413)
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. (2014) (394)
Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. (2010) (382)
Maintenance of Serotonin in the Intestinal Mucosa and Ganglia of Mice that Lack the High-Affinity Serotonin Transporter: Abnormal Intestinal Motility and the Expression of Cation Transporters (2001) (374)
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver (2009) (348)
Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy. (2011) (347)
The SLC22 family with transporters of organic cations, anions and zwitterions. (2013) (344)
Organic cation transporters in intestine, kidney, liver, and brain. (1998) (331)
The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin (2009) (326)
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. (1998) (319)
The Role of SGLT1 and GLUT2 in Intestinal Glucose Transport and Sensing (2014) (314)
Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. (2013) (312)
A glucose sensor hiding in a family of transporters (2003) (309)
Drug specificity and intestinal membrane localization of human organic cation transporters (OCT). (2005) (247)
Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene (2001) (238)
Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences. (2002) (224)
Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. (2014) (223)
Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. (2005) (222)
Drug uptake systems in liver and kidney. (2003) (222)
Electrogenic Properties and Substrate Specificity of the Polyspecific Rat Cation Transporter rOCT1* (1996) (221)
Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (2014) (207)
Organic cation transporters. (2003) (199)
Localization of organic cation transporters OCT1 and OCT2 in rat kidney. (2000) (199)
Polyspecific organic cation transporters: their functions and interactions with drugs. (2004) (199)
Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion (2012) (192)
Functional expression of sodium-glucose transporters in cancer (2015) (182)
Glucose transporters in brain in health and disease (2020) (171)
SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy (2017) (171)
A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters (2005) (166)
Molecular Pharmacology of Organic Cation Transporters in Kidney (1999) (159)
Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. (2012) (150)
DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma (2011) (147)
Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody. (2008) (144)
Acetylcholine and molecular components of its synthesis and release machinery in the urothelium. (2007) (142)
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. (2001) (138)
Amino Acids Critical for Substrate Affinity of Rat Organic Cation Transporter 1 Line the Substrate Binding Region in a Model Derived from the Tertiary Structure of Lactose Permease (2005) (134)
Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells. (2002) (133)
Organic Cation Transporters in Health and Disease (2020) (132)
Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3 (2009) (128)
Membrane localization of the electrogenic cation transporter rOCT1 in rat liver. (1998) (121)
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. (1999) (120)
Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (117)
The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation. (2000) (117)
Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1 (1996) (116)
Reaction of monoclonal antibodies with plasma membrane proteins after binding on nitrocellulose: renaturation of antigenic sites and reduction of nonspecific antibody binding. (1987) (116)
Expression of the Na+‐d‐Glucose Cotransporter SGLT1 in Neurons (1997) (109)
Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus (2016) (108)
Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter. (1993) (107)
Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. (2001) (101)
Subtype-Specific Affinity for Corticosterone of Rat Organic Cation Transporters rOCT1 and rOCT2 Depends on Three Amino Acids within the Substrate Binding Region (2005) (101)
Organic cation transporter capable of transporting serotonin is up‐regulated in serotonin transporter‐deficient mice (2003) (98)
A Reevaluation of Substrate Specificity of the Rat Cation Transporter rOCT1* (1997) (98)
Mechanism of Electrogenic Cation Transport by the Cloned Organic Cation Transporter 2 from Rat* (2000) (97)
Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases. (2003) (92)
Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation. (2005) (89)
The Na+‐D‐glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer (2017) (82)
Regulation of the human organic cation transporter hOCT1 (2004) (82)
Glucose transporters in the small intestine in health and disease (2020) (81)
Role of organic cation transporters in drug–drug interaction (2015) (79)
Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse (2006) (78)
Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2. (2003) (77)
The structural organization of the mouse kidney (2004) (77)
The position of short and long loops of Henle in the rat kidney (2004) (77)
The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26. (1997) (75)
Transport of the new chemotherapeutic agent beta-D-glucosylisophosphoramide mustard (D-19575) into tumor cells is mediated by the Na+-D-glucose cotransporter SAAT1. (1998) (74)
ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. (2009) (73)
SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1. (2019) (72)
Substrate recognition and translocation by polyspecific organic cation transporters (2011) (70)
Characterization of regulatory mechanisms and states of human organic cation transporter 2. (2006) (70)
Localization of the Na+-d-glucose cotransporter SGLT1 in the blood-brain barrier (2004) (70)
Drug uptake transporters in antiretroviral therapy. (2011) (70)
The Large Extracellular Loop of Organic Cation Transporter 1 Influences Substrate Affinity and Is Pivotal for Oligomerization* (2011) (70)
Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. (2009) (69)
Down‐regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis (2004) (68)
INHIBITION OF OAT3-MEDIATED RENAL UPTAKE AS A MECHANISM FOR DRUG-DRUG INTERACTION BETWEEN FEXOFENADINE AND PROBENECID (2006) (67)
Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. (2007) (66)
Cell free expression and functional reconstitution of eukaryotic drug transporters. (2008) (65)
Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1) (2013) (61)
Mice without the Regulator Gene Rsc1A1 Exhibit Increased Na+-d-Glucose Cotransport in Small Intestine and Develop Obesity (2005) (60)
Cloning and expression of a rat brain L-glutamate transporter (1992) (59)
Osmotic diuresis by SGLT2 inhibition stimulates vasopressin‐induced water reabsorption to maintain body fluid volume (2020) (59)
Sodium‐glucose co‐transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes (2017) (58)
Five Amino Acids in the Innermost Cavity of the Substrate Binding Cleft of Organic Cation Transporter 1 Interact with Extracellular and Intracellular Corticosterone (2009) (58)
Human Organic Cation Transporter 1 Is Expressed in Lymphoma Cells and Increases Susceptibility to Irinotecan and Paclitaxel (2012) (58)
High-Affinity Cation Binding to Organic Cation Transporter 1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modeled Interaction Domain between Two Helices (2008) (57)
Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice (2016) (56)
Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule. (2009) (55)
The impact of high-fat diet on metabolism and immune defense in small intestine mucosa. (2015) (54)
Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart (2017) (52)
Transport of small organic cations in the rat liver (1996) (52)
Role of the renal sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats (2015) (49)
The Organic Cation Transporters rOCT1 and hOCT2 Are Inhibited by cGMP (2002) (49)
RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1. (2006) (48)
Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia. (2019) (48)
Alkali Cation Binding and Permeation in the Rat Organic Cation Transporter rOCT2* (2005) (47)
Rat renal glucose transporter SGLT1 exhibits zonal distribution and androgen-dependent gender differences. (2006) (47)
Downregulation of the Na+-D-glucose Cotransporter SGLT1 by Protein RS1 (RSC1A1) is Dependent on Dynamin and Protein Kinase C (2003) (47)
A Renal Olfactory Receptor Aids in Kidney Glucose Handling (2016) (47)
The Cation Transporters rOCT1 and rOCT2 Interact with Bicarbonate but Play Only a Minor Role for Amantadine Uptake into Rat Renal Proximal Tubules (2002) (47)
Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+. (2013) (45)
Reconstitution and partial purification of several Na+ cotransport systems from renal brush-border membranes. Properties of the L-glutamate transporter in proteoliposomes. (1984) (44)
SGLT1 sugar transporter/sensor is required for post-oral glucose appetition. (2016) (41)
An improved method for real-time monitoring of membrane capacitance in Xenopus laevis oocytes. (2002) (41)
3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3 (2007) (40)
Measurements of exponential gradients of sodium and chlorine in the rat kidney medulla using the electron microprobe (2004) (40)
Purification and functional reconstitution of the rat organic cation transporter OCT1. (2005) (39)
Sucrose- and H+-Dependent Charge Movements Associated with the Gating of Sucrose Transporter ZmSUT1 (2010) (39)
Mechanistic aspects of the cytotoxic activity of glufosfamide, a new tumour therapeutic agent (2000) (39)
Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. (2018) (38)
Methodological aspects of purification and reconstitution of transport proteins from mammalian plasma membranes. (1986) (37)
A Substrate Binding Hinge Domain Is Critical for Transport-related Structural Changes of Organic Cation Transporter 1* (2012) (35)
Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent (2009) (35)
Chronic Pressure Overload Induces Cardiac Hypertrophy and Fibrosis via Increases in SGLT1 and IL-18 Gene Expression in Mice. (2018) (34)
Addition of NMDA-receptor antagonist MK801 during oxygen/glucose deprivation moderately attenuates the upregulation of glucose uptake after subsequent reoxygenation in brain endothelial cells (2012) (34)
Duodenal-Jejunal Bypass Improves Glycemia and Decreases SGLT1-Mediated Glucose Absorption in Rats With Streptozotocin-Induced Type 2 Diabetes (2013) (34)
Partial purification and reconstitution of the Na+-D-glucose cotransport protein from pig renal proximal tubules. (1983) (34)
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat. (2018) (34)
Na(+)-D-glucose cotransporter in muscle capillaries increases glucose permeability. (2004) (34)
The Plasma Membrane-associated Protein RS1 Decreases Transcription of the Transporter SGLT1 in Confluent LLC-PK1 Cells* (2001) (34)
Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus. (2006) (34)
Tripeptides of RS1 (RSC1A1) Inhibit a Monosaccharide-dependent Exocytotic Pathway of Na+-d-Glucose Cotransporter SGLT1 with High Affinity* (2007) (33)
Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters. (2003) (33)
Multiple binding sites in organic cation transporters require sophisticated procedures to identify interactions of novel drugs (2018) (33)
Expression profiling and immunolocalization of Na+-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats (2017) (32)
Voltage and substrate dependence of the inverse transport mode of the rabbit Na+/glucose cotransporter (SGLT1) (2000) (30)
Electron microscopic immunohistochemical localization of components of Na+-cotransporters along the rat nephron. (1989) (30)
Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse (2007) (30)
Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug–drug interactions (2015) (29)
Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron. (2016) (29)
Cloning and characterization of the transport modifier RS1 from rabbit which was previously assumed to be specific for Na+-D-glucose cotransport. (1999) (28)
The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium (2012) (28)
The human gene of a protein that modifies Na(+)-D-glucose co-transport. (1996) (28)
Targeting of sodium-glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han:SPRD rats. (2013) (28)
Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity. (2007) (27)
Structure and Function of Renal Organic Cation Transporters. (1998) (27)
Knockout of Na-glucose-cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase-1 in macula densa and glomerular hyperfiltration (2019) (27)
Characterization and histochemical localization of the rat intestinal Na(+)-D-glucose cotransporter by monoclonal antibodies. (1990) (27)
Liver X receptor-activating ligands modulate renal and intestinal sodium-phosphate transporters. (2011) (26)
Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion. (2019) (25)
Pattern of luminal diameter changes along the descending and ascending thin limbs of the loop of Henle in the inner medullary zone of the rat kidney (2004) (25)
The transport modifier RS1 is localized at the inner side of the plasma membrane and changes membrane capacitance. (2000) (25)
Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression. (2003) (25)
Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy (2017) (24)
Comparison of a Na+/D-glucose cotransporter from rat intestine expressed in oocytes of Xenopus laevis with the endogenous cotransporter. (1991) (24)
A simple liposomal system to reconstitute and assay highly efficient Na+/D-glucose cotransport from kidney brush-border membranes. (1983) (24)
Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice (2015) (24)
Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine. (2009) (24)
Rat Organic Cation Transporter 1 Contains Three Binding Sites for Substrate 1-Methyl-4-phenylpyridinium per Monomer (2018) (24)
Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model. (2019) (24)
Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA‐methyltransferase inhibitors (2014) (23)
Polyspecific organic cation transporters and their biomedical relevance in kidney (2013) (23)
Monoclonal antibodies against the renal Na+-D-glucose cotransporter. Identification of antigenic polypeptides and demonstration of functional coupling of different Na+-cotransport systems. (1988) (22)
Phosphorylation of RS1 (RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption (2016) (22)
Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced in vitro testing (2021) (22)
The Würzburg Anatomical Institute and its supply of corpses (1933-1945). (2012) (21)
Different classes of nucleotide binding sites in the (Na+ + K+)-ATPase studied by affinity labeling and nucleotide-dependent SH-group modifications. (1982) (20)
Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine uptake and cytotoxicity in chronic lymphocytic leukemia (CLL) cells (2015) (20)
Cyclosporin binding to a protein component of the renal Na(+)-D-glucose cotransporter. (1990) (18)
Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake (2018) (18)
Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1 (2020) (18)
Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions (2016) (17)
Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin. (2018) (17)
SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice (2017) (17)
Absolute protein quantification allows differentiation of cell‐specific metabolic routes and functions (2015) (17)
Endogenous L-glutamate transport in oocytes of Xenopus laevis. (1991) (17)
A monoclonal antibody against a Na(+)-L-glutamate cotransporter from rat brain. (1992) (16)
Nitric oxide-induced regulation of renal organic cation transport after renal ischemia-reperfusion injury. (2011) (16)
Identification of the D‐glucose binding polypeptide of the renal Na+‐D‐glucose cotransporter with a covalently binding D‐glucose analog (1985) (15)
General Overview of Organic Cation Transporters in Brain. (2021) (15)
Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions (2017) (15)
RECONSTITUTION OF D‐GLUCOSE TRANSPORT AND HIGH‐AFFINITY PHLORIZIN BINDING AFTER SOLUBILIZATION OF KIDNEY BRUSH BORDER PROTEINS (1980) (15)
Function and presumed molecular structure of Na+-D-glucose cotransport systems (1994) (15)
Reconstitution and fractionation of renal brush border transport proteins. (1990) (15)
Channels in planar bilayers made from commercially available lipids (1984) (15)
Identification of D-glucose-binding polypeptides which are components of the renal Na+-D-glucose cotransporter. (1987) (14)
Novel Shuttling Domain in a Regulator (RSC1A1) of Transporter SGLT1 Steers Cell Cycle‐Dependent Nuclear Location (2009) (14)
Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes (2016) (14)
Role of the Transporter Regulator Protein (RS1) in the Modulation of Concentrative Nucleoside Transporters (CNTs) in Epithelia (2012) (14)
Structure and function of the sodium and potassium-coupled glutamate transporter from rat brain. (1993) (13)
Identification of an Mr 75000 component of the H+/D-glucose cotransporter from Zea mays with monoclonal antibodies directed against the mammalian Na+/D-glucose cotransporter. (1989) (12)
Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity? (2014) (12)
Synthesis of 18F-fluoroalkyl-beta-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters. (2003) (12)
New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans. (2021) (11)
RS 1 ( RSC 1 A 1 ) regulates the exocytotic pathway of Na-D-glucose cotransporter SGLT 1 (2006) (11)
Ileal Interposition in Rats with Experimental Type 2 Like Diabetes Improves Glycemic Control Independently of Glucose Absorption (2015) (11)
Polyspecific cation transporters in the proximal tubule. (2000) (11)
Two substrate sites in the renal Na+-d-glucose cotransporter studied by model analysis of phlorizin binding and-d-glucose transport measurements (1990) (10)
Analysis of Na+-D-glucose cotransporter and other renal brush border proteins in human urine. (1991) (10)
Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis (2014) (9)
Interaction of phlorizin with the Na+―D-glucose cotransporter from intestine and kidney (1987) (9)
Protein kinase C–dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells (2009) (9)
Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet (2018) (8)
PHOTOAFFINITY LABELING OF MEMBRANE PROTEINS FROM RAT LIVER AND PIG KIDNEY WITH CYCLOSPORINE DIAZIRINE (1988) (8)
RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury (2018) (8)
Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase (2016) (8)
In vivo two-photon fluorescence microscopy opens a new area for investigation of the excretion of cationic drugs in the kidney. (2007) (7)
Characteristics of antibody inhibition of rat kidney (Na+−K+)-ATPase (1978) (6)
Giant MDCK cells: a novel expression system. (1990) (5)
SGLT1 participates in the development of vascular cognitive impairment in a mouse model of small vessel disease (2020) (5)
Erratum: Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (5)
Response to Comment on: Gorboulev et al. Na+-d-glucose Cotransporter SGLT1 Is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion. Diabetes 2012;61:187–196 (2012) (5)
A special issue on glucose transporters in health and disease (2020) (5)
Response to “Tenofovir Disoproxil Fumarate Is Not an Inhibitor of Human Organic Cation Transporter 1” (2017) (5)
Oxidative stress and Na+-glucose cotransporters Sglt1 and Sglt2 in kidneys of ochratoxin A-treated rats (2011) (4)
Role of the macula densa sodium glucose cotransporter type 1-nitric oxide synthase 1-tubuloglomerular feedback pathway in diabetic hyperfiltration. (2021) (4)
Sequence analysis of the catalytic subunit of H(+)-ATPase from porcine renal brush-border membranes. (1992) (4)
Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD (2018) (4)
An analysis of biphasic time courses: the inactivation of (Na+ + K+)-ATPase and Ca2+-ATPase by ATP-analogs. (1983) (4)
Erratum to the report of the third international workshop on human Y chromosome mapping 1997 (1997) (4)
Absence of the Na‐Glucose Cotransporter SGLT1 Ameliorates Kidney Recovery in a Murine Model of Acute Kidney Injury (2018) (3)
Conformational changes of membrane-bound (Na+−K+)-ATPase as revealed by antibody inhibition (1979) (3)
A Modified Tripeptide Motif of RS1 (RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose (2018) (3)
Measurement of Na K ATPase activity in segments of proximal tubules from superficial and juxtamedullary rat nephrons during antidiuresis (1976) (3)
SGLT 2 and SGLT 1 renal expression in patients with type 2 diabetes (2017) (3)
Roct1, a rat polyspecific transporter gene for the excretion of cationic drugs, maps to Chromosome 1q11-12 (1996) (3)
Characterization of p-aminohippurate transport from rat kidney which is expressed after injection of size-selected mRNA into oocytes of Xenopus laevis. (1993) (2)
Organic Anion and Cation Transporters in Renal Elimination of Drugs (2013) (2)
What makes SGLT2 inhibition so effective in lowering blood glucose in diabetes? (689.5) (2014) (2)
Organic Cation and Zwitterion Transporters (OCTs, OCTNs) (2014) (2)
Antidiabetic Effects of a Tripeptide That Decreases Abundance of Na+-d-glucose Cotransporter SGLT1 in the Brush-Border Membrane of the Small Intestine (2020) (2)
Conformational changes of membrane-bound (Na+−K+)-ATPase as revealed by trypsin digestion (1979) (2)
Structure of Na+-D-Glucose Cotransport Systems (1994) (2)
Functional Properties of Organic Cation Transporter OCT1, Binding of Substrates and Inhibitors, and Presumed Transport Mechanism (2016) (2)
High-affinity Cation Binding to Transporter OCT 1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modelled Interaction Domain between Two Helices (2007) (2)
Contribution of SGLT1 in cardiac glucose uptake (2018) (1)
Molecular pharmacology of organic cation transport (2000) (1)
A radioimmunoassay to screen for antibodies to native conformational antigens and analyse ligand-induced structural states of antigenic proteins. (1988) (1)
The SGLT2 Inhibitor, Empagliflozin, Attenuates Some Markers of Renal Fibrosis without Improving Albuminuria in Diabetic Db/Db Mice (2016) (1)
Assignment of the membrane-associated modulator of the Na(+)-sugar cotransport systems gene RSC1A1 to human chromosome 1p36.1 by in situ hybridization. (1996) (1)
Monoclonal antibodies against luminal membranes of renal proximal tubules which are kidney-specific. (1993) (1)
CHAPTER 73 – Organic Anion and Cation Transporters in Renal Elimination of Drugs (2008) (1)
Attempts to purify the renal Na+-D-glucose cotransport protein (1985) (1)
Plenary Lectures, Oral Sessions, Poster Sessions and Symposia (2002) (1)
Substructure of membrane-bound Na+−K+-ATPase protein (1979) (1)
Immunological characterization of Na+ and K+ mediated structural states of rat kidney Na+-k+-ATPase. (1977) (1)
907 - Deficits in Apical Sodium and Water Transporters Along with Maintenance of CFTR Account for Diarrheal Pathology in MYO5B Ko Mice and Patients with MVID (2018) (1)
Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes (2023) (1)
Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis (2014) (1)
No extrarenal expression of SGLT2 and sex differences in renal expression (2012) (1)
Real-time monitoring of plasma membrane dynamics in Xenopus oocytes using a simple and robust method to measure capacitance (2001) (0)
Immunodetection of Na+-D-glucose cotransporters hSGLT1 and hSGLT2 in human organs (2008) (0)
by PKA, PI3K, and calmodulin-dependent kinases Regulation of human organic cation transporter hOCT2 (2016) (0)
Functional expression of human organic cation transporter 3 in renal cancer cells (2008) (0)
SFB 35 tranSmembrane tranSporterS In HeaLtH and dISeaSe (2010) (0)
Contents, Vol. 4, 1994 (1994) (0)
Salvia fruticosa tea drinking reduces the expression of sodium/glucose cotransporter 1 in enterocytes brush-border membrane of streptozotocin-induced diabetic rats (2007) (0)
Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (2014) (0)
A08 Deficiency in Sodium-Dependent Glucose Transporter 1 has no Effect on Brain Edema Formation after Traumatic Brain Injury (2012) (0)
OCT-2, Organic Cation Transporter 2 (2008) (0)
SODIUM-D-GLUCOSE COTRANSPORTER SGLT1 (SLC5A1) IN MOUSE (2013) (0)
3 2 DRUG UPTAKE SYSTEMS IN LIVER AND KIDNEY (2001) (0)
Hepatocellular uptake of organic cations by the organic anion transporting polypeptides (Oatp1, Oatp2 and OATP-A) and the organic cation transporters (rOCT1 and hOCT1) (2000) (0)
Cancer Therapy : Preclinical Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 ( OCT 1 ) (2014) (0)
Gender differences in rat renal Na+-glucose cotransporter SGLT1 (2005) (0)
The binding of drugs to organic cation transporters and their translocation across the plasma membrane (2005) (0)
Expression profiling and immunolocalization of Na+-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats (2017) (0)
[Cortico-medullary water distribution in rat kidneys during anti- and water-diuresis]. (1976) (0)
Already published in CDM) Drug Uptake Systems in Liver and Kidney (2004) (0)
differences and androgen-dependent gender Rat renal glucose transporter SGLT1 exhibits zonal (2006) (0)
Leptin mediates downregulation of intestinal SGLT1 and hyperplasia in obese type 2 diabetic mice (2016) (0)
Interaction of antihypertensives and antibiotics with hepatic (hOCT1) and renal (hOCT2) human organic cation transporters (2006) (0)
OCTN-2, Organic Cation-Sodium Transporter 2 (2008) (0)
Expression of sodium-D-glucose cotranspotre SGLT1 (SLC5A1) in murine organs (2013) (0)
OCT-3, Organic Cation Transporter 3 (2008) (0)
TripeptidesofRS1(RSC1A1)InhibitaMonosaccharide-dependent Exocytotic Pathway of Na-D-Glucose Cotransporter SGLT1 (2007) (0)
Chapter 2 Functional Properties of Organic Cation Transporter OCT 1 , Binding of Substrates and Inhibitors , and Presumed Transport Mechanism (2017) (0)
Subject Index, Vol. 79, 1997 (1997) (0)
antibody SGLT1 in rat organs with an improved Revised immunolocalization of the Na+-D-glucose (2008) (0)
Brush-border and basolateral transporters of organic compounds in acute and subchronic models of experimental cadmium nephrotoxicity in rats (2013) (0)
Transport of mutagenic vital dye ethidium bromide by the human organic cation transporters hOCT2 and hOCT3 (2008) (0)
Design of Nanohydrogels for Targeted Intracellular Drug Transport to the Trans-Golgi Network. (2023) (0)
26 Obstructive cholestasis results in down-regulation and functional impairment of the organic cation transporter 1 (OCT1) in rat (2003) (0)
Proximal Tubular Transport of Organic Compounds Polyspecific cation transporters in the proximal tubule (2000) (0)
The A BC o f S olute C arriers (2004) (0)
G-protein coupled receptors for succinate (GPR91)and alpha ketoglutarate (GPR99) are differently localized in the human and mouse nephron (2007) (0)
Contribution of SGLT1 in cardiac glucose transport (2019) (0)
IDENTIFICATION OF COMPONENTS OF NA+-D-GLUCOSE COTRANSPORT PROTEINS IN BRUSH-BORDER MEMBRANES FROM RENAL CORTEX (1987) (0)
Monoclonal Antibodies against the Renal Na +-D-Glucose Cotransporter IDENTIFICATION OF ANTIGENIC POLYPEPTIDES AND DEMONSTRATION OF FUNCTIONAL COUPLING OF (2001) (0)
Impaired Regulation of Renal K Elimination in Mice Lacking SGLT1 (2012) (0)
Na+-glucose co-transporter SGLT2 in rat kidney (2007) (0)
Regulation of the Na +-D-glucose cotransporter SGLT 1 in small intestine in response to bariatric surgery and peptides derived from protein RS 1 ( RSC 1 A 1 ) (2015) (0)
Knockout of Na‐glucose transporter SGLT1 lowers GFR and kidney weight in non‐diabetic and Akita diabetic mice (2016) (0)
Lack of SGLT1 enhances renal oxidative stress, reduces kidney weight, and blunts diabetic glomerular hyperfiltration (2011) (0)
Urinary excretion of renal tubular cell proteins after cisplatinum therapy (1993) (0)
Age-related expression of organic compound and water transporters in rat kidneys (2013) (0)
Will inhibitors of glucose transport in the diabetes therapy act specifically in the kidneys (2015) (0)
Abstract 885: Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine cytotoxic action. (2013) (0)
Subject Index, Vol. 4, 1994 (1994) (0)
Membrane transporters of organic compounds in experimental cadmium nephrotoxicity (2012) (0)
Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg (1990) (0)
Subject Index, Vol. 73, 1996 (1996) (0)
[Electron probe microanalysis determination of the corticomedullary gradient of sodium and chlorine in the rat kidney]. (1974) (0)
Inhibitors of glucose transporter SGLT1 in the treatment of diabetes mellitus will not act only in the kidneys ; the transporter is also present in other rodent and human organs (2015) (0)
Contents, Vol. 79, 1997 (1997) (0)
A Single Dose of Oral Metformin Reduces the Post-Prandial Glucose Response Through a Transient Modulation of Apical Sodium-Glucose Co-Transporter (2019) (0)
Structurally Different Nucleotide Binding Sites in Na,K-ATPase (1983) (0)
The human organic cation transporter 2 (hOCT2) transports cadmium (Cd2+) and mediates Cd2+ induced cell death (2008) (0)
Evaluation of the Influence of Biosurface Design on the Interaction between the Regulatory Peptide RS1‐reg and ODC1 Reveals a Membrane‐Dependent Affinity Increase (2022) (0)
Leptin but not its long form receptor regulates intestinal membrane expression of sodium/glucose transporter‐1 and intestinal hyperplasia (2013) (0)
Deficits in Enterocyte Apical Transporters Associated with Loss of Myosin VB (2017) (0)
Transport proteins that determines the transport of xenobiotics and / or cationic drugs, DNA sequences encoding same and its use. (1995) (0)
Evidence for three atp binding sites in the (Na+ + K+)-ATPase (1979) (0)
MEMBRANE TRANSPORTERS IN EXPERIMENTAL CADMIUM NEPHROTOXICITY (2012) (0)
Potential Harmful Effects of The Novel Anti-Diabetics, Inhibitors of Sodium-Glucose Cotransporters SGLT1 and SGLT2 (2016) (0)
CELLULAR LOCALIZATION AND SEX-RELATED PROTEIN EXPRESSION OF ORGANIC CATION TRANSPORTERS OCT1 AND OCT2 IN MOUSE KIDNEYS AND LIVER (2014) (0)
Interaction of drugs at organic cation transporters in the plasma membrane: Mechanistics, risks and benefits (2013) (0)
Renal Olfactory Receptor 1393 Contributes to the Progression of Diabetes (2018) (0)
Sodium-glucose cotransporter Sglt1 (Slc5a1) is present in various murine organs : sex-related expression in kidneys (2015) (0)
Gender and species differences in the mammalian organic cation transporters (2010) (0)
Acute kidney injury - Experimental models (2011) (0)
Identiﬁcation of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate afﬁnity (2007) (0)
Immunochemical characterization of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidneys, small intestine and liver (2009) (0)
Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy (2017) (0)
Transcriptional and post-transcriptional regulation of SGLT1 by RS1 (2005) (0)
Renal expression and localization of sodium-d-glucose cotransporter 1 (SGLT1) is different in rats and mice (2012) (0)
EXPRESSION OF SODIUM-D-GLUCOSE COTRANSPORTER 1 IN MURINE TISSUES ; SEX-DEPENDENT EXPRESSION IN KIDNEYS (2014) (0)
Indications of several nucleotide binding sites on the Na+ -K+-ATPase molecule. (1980) (0)
Species differences in the expression of sodium-D-glucose cotransporter 1 (SGLT1/SLC5A1), a potential therapeutic target in diabetes (2016) (0)
OCT-1, Organic Cation Transporter 1 (2008) (0)
Immunolocalization of the Na+-Glucose Cotransporter SGLT1 in Male and Female Rats with an Improved Antibody (2007) (0)

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