Hidekazu Tsukamoto
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Computer Science
Hidekazu Tsukamoto's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science Kyoto University
- Bachelors Computer Science Kyoto University
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(Suggest an Edit or Addition)Hidekazu Tsukamoto's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis (2012) (625)
- Enteric dysbiosis associated with a mouse model of alcoholic liver disease (2011) (598)
- Experimental liver cirrhosis induced by alcohol and iron. (1995) (492)
- Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation* (2000) (455)
- Current concepts in the pathogenesis of alcoholic liver injury (2001) (380)
- Alcoholic liver disease (2018) (366)
- MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. (2010) (360)
- StellaTUM: current consensus and discussion on pancreatic stellate cell research (2011) (351)
- Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression. (2009) (317)
- Stimulation of hepatic lipocyte collagen production by Kupffer cell‐derived transforming growth factor β: Implication for a pathogenetic role in alcoholic liver fibrogenesis (1990) (307)
- Exacerbation of alcoholic liver injury by enteral endotoxin in rats (2000) (283)
- Experimental models of hepatic fibrosis: a review. (1990) (279)
- Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells* (2004) (270)
- Ethanol‐induced liver fibrosis in rats fed high fat diet (1986) (269)
- Oxidative stress and liver disease. (1996) (268)
- Adipogenic Transcriptional Regulation of Hepatic Stellate Cells* (2005) (264)
- Septum transversum‐derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver (2011) (256)
- Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis. (2008) (248)
- Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. (2015) (237)
- Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet (1985) (231)
- Role of cytochrome P‐450 2E1 in ethanol‐, carbon tetrachloride— and iron‐dependent microsomal lipid peroxidation (1992) (225)
- Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide. (1999) (220)
- Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog (2009) (218)
- Steatohepatitis induced by intragastric overfeeding in mice (2005) (216)
- Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats (1992) (215)
- Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease (1995) (212)
- Epigenetic regulation of connective tissue growth factor by MicroRNA‐214 delivery in exosomes from mouse or human hepatic stellate cells (2014) (205)
- Increased 4‐hydroxynonenal levels in experimental alcoholic liver disease: Association of lipid peroxidation with liver fibrogenesis (1992) (203)
- Inflammation in Alcoholic and Nonalcoholic Fatty Liver Disease: Friend or Foe? (2016) (193)
- Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver. (2000) (192)
- Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice (2013) (184)
- Inflammatory pathways in alcoholic steatohepatitis. (2019) (181)
- Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. (2004) (176)
- Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development (2009) (176)
- Insights into the pathogenesis of alcoholic liver necrosis and fibrosis: Status report (1990) (175)
- NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. (2015) (167)
- Ethanol-induced hepatic fibrosis in the rat: role of the amount of dietary fat. (1986) (167)
- Long-term cannulation model for blood sampling and intragastric infusion in the rat. (1984) (160)
- Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. (2011) (157)
- Cytokine regulation of hepatic stellate cells in liver fibrosis. (1999) (153)
- Expression of Interleukin-10 by in Vitro and in Vivo Activated Hepatic Stellate Cells* (1998) (151)
- Mitochondrial glutathione depletion in alcoholic liver disease. (1993) (150)
- Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells. (2004) (145)
- Essential Role of Matrix Metalloproteinases in Interleukin-1-induced Myofibroblastic Activation of Hepatic Stellate Cell in Collagen* (2004) (145)
- Signaling Role of Intracellular Iron in NF-κB Activation* (2003) (145)
- Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients (2018) (139)
- Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption. (2004) (137)
- Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells. (2013) (133)
- Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK. (2011) (133)
- Ethanol-Induced Expression of ET-1 and ET-BR in Liver Sinusoidal Endothelial Cells and Human Endothelial Cells Involves Hypoxia-Inducible Factor-1α and MicroRNA-1991 (2009) (132)
- Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models (2016) (131)
- Epigenetic regulation of miR-34a expression in alcoholic liver injury. (2012) (127)
- Roles of oxidative stress in activation of Kupffer and Ito cells in liver fibrogenesis (1995) (125)
- Cyclical pattern of blood alcohol levels during continuous intragastric ethanol infusion in rats. (1985) (119)
- Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator‐activated receptor γ in hepatic stellate cells for their antifibrotic effect (2012) (111)
- Iron primes hepatic macrophages for NF-κB activation in alcoholic liver injury. (1999) (109)
- Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6. (2017) (109)
- Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation (2012) (109)
- Diminished retinoic acid signaling in hepatic stellate cells in cholestatic liver fibrosis. (1997) (108)
- Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via β‐catenin activation (2007) (108)
- Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein. (2011) (107)
- Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease. (2011) (106)
- Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1. (2009) (104)
- Iron activates NF-κB in Kupffer cells (2002) (102)
- Potentiation of ethanol-induced pancreatic injury by dietary fat. Induction of chronic pancreatitis by alcohol in rats. (1988) (101)
- Oxidative stress, antioxidants, and alcoholic liver fibrogenesis. (1993) (100)
- Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice (2015) (93)
- "Second hit" models of alcoholic liver disease. (2009) (89)
- Role of abnormal methionine metabolism in alcoholic liver injury. (2002) (89)
- Incomplete compensation of enhanced hepatic oxygen consumption in rats with alcoholic centrilobular liver necrosis (1989) (89)
- A Matrix Metalloproteinase-9 Activation Cascade by Hepatic Stellate Cells in Trans-differentiation in the Three-dimensional Extracellular Matrix* (2007) (88)
- c‐Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide–dependent impairment of oxidative DNA repair (2010) (88)
- Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells (2011) (88)
- Anti‐adipogenic regulation underlies hepatic stellate cell transdifferentiation (2006) (85)
- Hemojuvelin-Neogenin Interaction Is Required for Bone Morphogenic Protein-4-induced Hepcidin Expression* (2009) (85)
- WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes. (1998) (83)
- S‐adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model (2009) (81)
- Redox regulation of cytokine expression in Kupffer cells. (2002) (80)
- Alcoholic hepatitis: Translational approaches to develop targeted therapies (2016) (80)
- Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood (2017) (79)
- Signaling role of intracellular iron in NF-kappaB activation. (2003) (78)
- Iron-dependent activation of NF-kappaB in Kupffer cells: a priming mechanism for alcoholic liver disease. (2003) (77)
- A rat model reproducing key pathological responses of alcoholic chronic pancreatitis. (2008) (77)
- Epigenetic regulation of hepatic endoplasmic reticulum stress pathways in the ethanol‐fed cystathionine beta synthase–deficient mouse (2010) (75)
- Mouse intragastric infusion (iG) model (2012) (75)
- IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. (2019) (73)
- How is the liver primed or sensitized for alcoholic liver disease? (2001) (71)
- Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration* (2012) (71)
- Alcohol directly stimulates epigenetic modifications in hepatic stellate cells. (2015) (70)
- Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis. (2012) (69)
- Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation. (2007) (69)
- Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine. (2004) (68)
- Dynamic Adaptation of Liver Mitochondria to Chronic Alcohol Feeding in Mice (2012) (66)
- Effect of ethanol and high‐fat feeding on hepatic γ‐glutamylcysteine synthetase subunit expression in the rat (1999) (66)
- Adipogenic phenotype of hepatic stellate cells. (2005) (64)
- Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury. (1999) (64)
- Iron Causes Interactions of TAK1, p21ras, and Phosphatidylinositol 3-Kinase in Caveolae to Activate IκB Kinase in Hepatic Macrophages* (2007) (61)
- Sensitization of hepatic lipocytes by high‐fat diet to stimulatory effects of kupffer cell‐derived factors: Implication in alcoholic liver fibrogenesis (1990) (59)
- PPAR Gamma and Hepatic Stellate Cells (2004) (59)
- Tumor necrosis factor-α inhibits peroxisome proliferator-activated receptor γ activity at a posttranslational level in hepatic stellate cells (2004) (58)
- A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A (2017) (58)
- Peroxisome Proliferator-activated Receptor γ Suppresses Proximal α1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells* (2005) (57)
- Iron activates NF-kappaB in Kupffer cells. (2002) (56)
- Effect of thioacetamide on the hepatic expression of gamma-glutamylcysteine synthetase subunits in the Rat. (1999) (54)
- Changes in the expression of methionine adenosyltransferase genes and S‐adenosylmethionine homeostasis during hepatic stellate cell activation (2009) (54)
- Increased Iron Loading Induces Bmp6 Expression in the Non-Parenchymal Cells of the Liver Independent of the BMP-Signaling Pathway (2013) (53)
- Intragastric ethanol infusion model in rodents. (2008) (53)
- Expression of carboxylesterase and lipase genes in rat liver cell-types. (2008) (52)
- The Necdin-Wnt Pathway Causes Epigenetic Peroxisome Proliferator-activated Receptor γ Repression in Hepatic Stellate Cells* (2010) (51)
- Ethanol Augments RANTES/CCL5 Expression in Rat Liver Sinusoidal Endothelial Cells and Human Endothelial Cells via Activation of NF-κB, HIF-1α, and AP-11 (2009) (51)
- Baicalein Targets GTPase‐Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition (2018) (51)
- Epigenetic cell fate regulation of hepatic stellate cells (2011) (49)
- Conceptual importance of identifying alcoholic liver disease as a lifestyle disease (2007) (48)
- Is interleukin‐10 antifibrogenic in chronic liver injury? (1998) (48)
- TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I. (2009) (46)
- Low Intracellular Iron Increases the Stability of Matriptase-2* (2014) (44)
- Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis. (2008) (44)
- Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus (2012) (44)
- Effects of dietary polyunsaturated fat on ethanol-induced Ito cell activation. (1996) (42)
- The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury (2017) (42)
- Differential effects of interleukin-1 alpha, tumor necrosis factor alpha, and transforming growth factor beta 1 on cell proliferation and collagen formation by cultured fat-storing cells. (1989) (42)
- The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading (2017) (42)
- Alpha-smooth muscle actin expression in tumor and stromal cells of benign and malignant human pigment cell tumors. (1992) (41)
- IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells. (2002) (41)
- Relationship between fatty liver and subsequent development of necrosis, inflammation and fibrosis in experimental alcoholic liver disease. (1989) (39)
- Iron regulation of hepatic macrophage TNFα expression (2002) (39)
- Morphogens and hepatic stellate cell fate regulation in chronic liver disease (2012) (38)
- Fat paradox in liver disease. (2005) (37)
- Destabilization of TNF-α mRNA by retinoic acid in hepatic macrophages: implications for alcoholic liver disease (2001) (37)
- Cell Death and Liver Disease (2019) (35)
- Fat paradox of steatohepatitis (2008) (33)
- Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells. (2004) (33)
- Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. (2020) (32)
- Alcohol Induces RNA Polymerase III-dependent Transcription through c-Jun by Co-regulating TATA-binding Protein (TBP) and Brf1 Expression* (2010) (32)
- Signaling role of iron in NF-kappa B activation in hepatic macrophages (2004) (32)
- Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport. (2010) (31)
- Lack of evidence for increased lipid peroxidation in ethanol-induced centrilobular necrosis of rat liver. (2008) (31)
- Hepatic stellate cell nomenclature. (1996) (30)
- Gadolinium chloride-induced hepatocyte proliferation is prevented by antibodies to tumor necrosis factor alpha. (2001) (30)
- Stearoyl-CoA desaturase and tumorigenesis. (2019) (29)
- Destabilization of TNF-alpha mRNA by retinoic acid in hepatic macrophages: implications for alcoholic liver disease. (2001) (29)
- TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome. (2016) (28)
- Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science (2019) (26)
- Differential effects of interleukin‐1α, tumor necrosis factor α, and transforming growth factor β1 on cell proliferation and collagen formation by cultured fat‐storing cells (2008) (26)
- Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells (2014) (26)
- Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. (2020) (26)
- Iron regulation of hepatic macrophage TNFalpha expression. (2002) (24)
- Dietary modulation of alcohol-induced pancreatic injury. (1993) (24)
- Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice (2020) (24)
- Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse. (2014) (24)
- Demographic characteristics of hospitalized patients with alcoholic liver disease and pancreatitis in los angeles county. (2003) (24)
- The altered expression of α‐smooth muscle actin in basal cell epithelioma and its surrounding stroma: with special reference to proliferating cell nuclear antigen expression and adenoid differentiation (1994) (23)
- Wnt Pathway Stabilizes MeCP2 Protein to Repress PPAR-γ in Activation of Hepatic Stellate Cells (2016) (23)
- The Role of IL-17 Signaling in Regulation of the Liver–Brain Axis and Intestinal Permeability in Alcoholic Liver Disease (2016) (22)
- Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells. (2005) (22)
- Giant mitochondria induced in rat pancreatic exocrine cells by ethanol and iron (1996) (21)
- TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis. (2015) (20)
- Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis (2015) (20)
- Loss of the transforming growth factor‐β effector β2‐Spectrin promotes genomic instability (2017) (19)
- Publisher Correction: Alcoholic liver disease (2018) (19)
- Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1 (2017) (19)
- Introduction: Evolution of Intragastric Ethanol Infusion Model (1993) (18)
- Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese[S] (2016) (18)
- Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001. (2002) (18)
- Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases. (2017) (17)
- ALCOHOLIC LIVER DISEASE (ALD): A NEW DOMAIN FOR PREVENTION EFFORTS (2002) (16)
- Evolution of intragastric ethanol infusion model. (1993) (15)
- Chronic ethanol exposure combined with high fat diet up-regulates P2X7 receptors that parallels neuroinflammation and neuronal loss in C57BL/6J mice (2015) (15)
- Increased pancreatic acinar content and secretion of cationic trypsinogen following 30-day continuous ethanol intoxication in rats. (1986) (15)
- Reciprocal regulation by TLR 4 and TGF-b in tumor-initiating stem-like cells (2013) (14)
- Alcohol, TLR4-TGF-β antagonism, and liver cancer (2014) (14)
- Primary Alcohol‐Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene‐Expression Profiles (2020) (14)
- Epigenetic Regulation of Mir-34a Expression in Alcoholic Liver Injury (2011) (13)
- p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs (2020) (13)
- Ferroportin Q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption. (2008) (12)
- Metabolic reprogramming and cell fate regulation in alcoholic liver disease. (2015) (11)
- Hepatoprotective mechanisms of Yan-gan-wan. (2005) (11)
- Notch signaling and M1 macrophage activation in obesity-alcohol synergism. (2015) (11)
- Uncovering the liver’s role in immunity through RNA co-expression networks (2016) (11)
- New Approaches for Studying Alcoholic Liver Disease (2014) (10)
- Epigenetic mechanism of stellate cell trans-differentiation. (2007) (10)
- Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity (2014) (10)
- Caveosomal Oxidative Stress Causes Src-p21ras Activation and Lysine 63 TRAF6 Protein Polyubiquitination in Iron-induced M1 Hepatic Macrophage Activation* (2012) (9)
- Loss of the TGF-β Effector β2SP Promotes Genomic Instability. (2016) (9)
- Acetate reprograms gut microbiota during alcohol consumption (2022) (9)
- Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting. (2019) (8)
- A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution (2016) (8)
- Moderate Alcohol Intake Promotes Pancreatic Ductal Adenocarcinoma Development in Mice Expressing Oncogenic Kras. (2019) (8)
- ANIMAL MODELS OF ALCOHOLIC LIVER INJURY (1998) (8)
- Ethanol Diversely Alters Palmitate, Stearate, and Oleate Metabolism in the Liver and Pancreas of Rats Using the Deuterium Oxide Single Tracer (2009) (7)
- TGF-β enhances alcohol dependent hepatocyte damage via downregulation of alcohol dehydrogenase I (2009) (7)
- Hepatic origin of triglycerides in fatty livers produced by the continuous intragastric infusion of an ethanol diet (1984) (6)
- Cholecystokinin-induced secretion and synthesis of amylase and cationic trypsinogen by pancreatic acini isolated from rats given an ethanol diet. (1985) (6)
- Morphogen-related therapeutic targets for liver fibrosis. (2015) (6)
- Cell-to-Cell Communications in Alcohol-Associated Liver Disease (2022) (6)
- Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle (2023) (6)
- Differential activation of unconventional T cells, including iNKT cells, in alcohol-related liver disease. (2020) (6)
- A pilot study of an alcoholic liver disease recurrence prevention education program in hospitalized patients with advanced liver disease. (2005) (6)
- Fate and functional roles of Prominin 1+ cells in liver injury and cancer (2020) (6)
- Effects of cholecystokinin, food intake and cephalic stimuli on plasma levels of amylase, lipase, and immunoreactive cationic trypsinogen in rats. (1986) (5)
- Correlation of trypsin-plasma inhibitor complexes with mortality in experimental pancreatitis in rats (1986) (5)
- Immunoenzymometric determination of trypsin/alpha 1-protease inhibitor complex in plasma of rats with experimental pancreatitis. (1986) (5)
- Expression of TGFβ1 by Rat Kupffer Cells: Implication for a Pathogenetic Role in Alcoholic Liver Fibrosis a (1990) (5)
- Molecular mechanism of induced hepatic macrophage cytokine gene expression in experimental alcoholic liver injury. (1998) (4)
- 15th International Symposium on Cells of the Hepatic Sinusoid, 2010 (2011) (4)
- TGF-b/b2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome (2019) (2)
- Activation of Hepatic Stellate Cells: Anti-Adipogenic Differentiation? (2005) (2)
- Animal models for alcoholic liver disease (1989) (2)
- Hepatic stellate cells as a target for TZD: Can we treat liver fibrosis and type II diabetes at the same time? (2002) (2)
- Tissue distribution of an immunogenic melanoma associated antigen, D-1. (1994) (2)
- Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation (2021) (2)
- Dysplastic Nevus Syndrome: Melanoma‐prone Disease (1992) (2)
- Uncovering the liver’s role in immunity through RNA co-expression networks (2016) (1)
- Peroxisome Proliferator-Activated Receptor γ and Hepatic Stellate Cell Activation (2003) (1)
- DZNep attenuates liver fibrosis by blocking EZH2 and H3K27me3 (2012) (1)
- HIF-1 κ Cells via Activation of NF-Endothelial Cells and Human Endothelial Expression in Rat Liver Sinusoidal Ethanol Augments RANTES / CCL 5 (2009) (1)
- [Abnormal cholecystokinin-acinar function coupling in atrophied pancreatic acini from rats fed ethanol and a high-fat diet]. (1988) (1)
- PACRITAXEL AS A SECOND-LINE CHEMOTHERAPY AFTER FAILURE OF GEMCITABINE (2008) (1)
- MicroRNA-199 and α Hypoxia-Inducible Factor-1 and Human Endothelial Cells Involves ET-BR in Liver Sinusoidal Endothelial Cells Ethanol-Induced Expression of ET-1 and (2009) (1)
- Lipid peroxidation may not be important in an early stage of alcohol-induced liver injury (1986) (1)
- Notch, metabolism and macrophages (2015) (1)
- Increased hepatic JNK activation by ethanol is mediated by transcriptional suppression of mitogen‐activated protein kinase phosphatase 1 (Mkp1): role of cAMP‐specific protein kinase A (2021) (1)
- 930 Regulation of Hepatic Stellate Cell Activation by MicroRNA Let-7 Family During Alcoholic Liver Injury (2012) (1)
- Inhibitory effects of ethanol on phosphatidylinositol breakdown in pancreatic acini (1986) (1)
- Ethanol-Dependent Expression of Connective Tissue Growth Factor is Associated With Down-Regulation of MicroRNA 214 (2011) (1)
- 931 Regulation of Hepatic Stem/Progenitor Phenotype by Melatonin During Alcoholic Liver Injury (2012) (1)
- 211 Adipogenic regulation of hepatic stellate cell transdifferentiation (2003) (1)
- Mouse models of pancreatic cancer induced by chronic pancreatitis and smoking. (2014) (1)
- Emergence of highly profibrotic and proinflammatory Lrat+ Fbln2+ hepatic stellate cell subpopulation in alcoholic hepatitis. (2022) (0)
- TGF-b / b 2-spectrin / CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome (2019) (0)
- Abstract 892: Vitamin D deficiency regulates TLR7 to promote hepatocellular cancer in TGF-β/Smad3 heterozygous mice (2015) (0)
- Fatty Liver, Hepatitus, and Cirrhosis in Sub-Human Primates Fed Ethanol (1995) (0)
- 928 Deficiency of Intestinal Mucin-2 Protects From Alcoholic Liver Disease in Mice (2012) (0)
- The 14th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis (ISALPDC) (2020) (0)
- Suppression of hepatic hepcidin expression in response to acute iron deficiency is correlated with an increase of matripatase‐2 protein in the liver (2010) (0)
- Kenji Fujiwara, MD, PhD. (2013) (0)
- Tu1624 Dysregulated TGF-β Signaling Leads to Genomic Instability and Liver Cancer (2016) (0)
- Abstract 4331: Novel Wnt-SCD-LRP5/6 pathway linking liver fibrosis to cancer (2017) (0)
- 28 EPIGENETIC RELAY CONTROLS EXPRESSION OF THE MASTER FIBROGENIC AND METABOLIC REGULATOR PPARγ AND IS ESSENTIAL FOR ACTIVATION OF HEPATIC STELLATE CELLS (2009) (0)
- LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells (2023) (0)
- PPARγ AND HSC ACTIVATION (2001) (0)
- 1021 Inhibition of LPS-induced TNF-alpha promoter activity by S-adenlsylmethionine and 5′-methylthioadenosine (2003) (0)
- ASMase deficiency unmasks the dissociation between hyperhomocysteinemia and intrasgastric alcohol feeding-induced endoplasmic reticulum stress (2013) (0)
- Proceeding of the Ronald G. Thurman Memorial Symposium 2020 (2021) (0)
- Characterization of Endothelial Dysfunction in Microrna-34A Knockout Mice with Alcoholic Liver Injury (2017) (0)
- Current Understanding of Alcoholic Liver Disease: A prevalent "hidden" disease of increasing clinical importance (2018) (0)
- Abstract 4847: Alcoholic chronic pancreatitis increases tissue transformed macrophages (M2) which promote pancreatic cancer lesions in a Kras mouse model (2014) (0)
- α-Smooth muscle actin expression in stroma of basal cell epithelioma (BCE) (1991) (0)
- Expression of Intercellular Adhesion Molecule 1 by Activated Hepatic Stellate Cells (1998) (0)
- Metabolic reprogramming, cell fate decision and non-coding RNA in tumor-initiating stem-like cells (2018) (0)
- Combination of primers used to amplify open reading frame of the respective genes by real-time and semiquantitative PCR (2010) (0)
- Enhanced expression of TGFβ, collagen, and TIMP-1 genes in esophageal stricture* (2001) (0)
- Preface (2006) (0)
- Vitamin D as a Chemopreventive Agent for Hepatocellular Carcinoma in the Context of Impaired TGF-Beta Signaling Pathway (2014) (0)
- Analysis of cytotoxic activities of autologous lymphocytes activated by recombinant D-1 melanoma-associated antigen (1994) (0)
- Abstract 2540: Disruption of a TGF-β-CTCF regulated pathway leads to cancer stem cells (2016) (0)
- Reply (2015) (0)
- IRON, RETINOIC ACID AND KUPFFER CELL TNFα EXPRESSION IN ALD (2000) (0)
- Abstract 248: Vitamin D deficiency promotes hepatocellular carcinoma tumor growth in TGF-β impaired mice by Smad3 heterozygous deletion (2014) (0)
- 227 Increased liver damage in cytochrome P450 2E1 transgenic mice fed ethanol intragastrically for 4 weeks (2003) (0)
- INCREASED LIVER INJURY IN FEMALE RATS IS DUE TO HYPOXIA‐REOXYGENATION TRIGGERED BY ENDOTOXIN AND KUPFFER CELLS (1998) (0)
- Su1718 Regulation of MicroRNA-21 by Interleukin-6 During Alcoholic Liver Injury (2013) (0)
- 1283 Type I collagen and IL-1 serve as co-stimulatory signals for MMP-9 induction and hepatic stellate cell activation (2003) (0)
- 1296 Hormone sensitive lipase is a retinyl ester hydrolase in hepatic stellate cells (2003) (0)
- P0279 : SLC25A11 promotes cell proliferation in hepatocellular carcinoma spheroids and orthotopic tumor growth (2015) (0)
- S13 * MULTIPLE HITS IN THE PATHOGENESIS OF ALCOHOLIC LIVER DISEASE (2013) (0)
- Abstract 2447: Novel TLR4-Nanog stemness pathway in liver cancer stem cells confers resistance to TGF-β-mediated tumor suppression through YAP1 and IGF2BP3-AKT-mTOR (2011) (0)
- 1017 NRAMP1 mutation causes enhanced iron signaling for NF-KB activation and TNF-alpha expression in macrophages (2003) (0)
- A gene coding immunogenic melanoma-associated antigen: Characterization and tissue distribution in tumor and normal organs (1992) (0)
- New Molecular Insights Into Liver Fibrogenesis : Potential Therapies (2000) (0)
- p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs (2020) (0)
- Peroxisome Proliferator-activated Receptor (cid:1) Suppresses Proximal (cid:2) 1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells * (2005) (0)
- 387 Restoration of Intestinal Metabolic Homeostasis Results in Eubiosis and Protects Mice From Alcoholic Liver Disease (2014) (0)
- Mo1643 Diets With Subnormal Supplementation of Vitamin D Regimen Promote Hepatocellular Carcinoma Tumor Growth in TGF-β Impaired Mice With SMAD3 Heterozygous Deletion (2014) (0)
- Abstract 4893: ProtooncogenicTLR4induces NANOG-mediated oncogenic signaling via synergistic interaction with STAT3 pathway in experimental and clinical tumor-initiating cells. (2013) (0)
- Why Do Hepatic Macrophages and Stellate Cells Become Dysregulated in Alcoholic Liver Disease? (Special Issue July 2004: Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis Research Center--University of Southern California, Los Angeles, U.S.A.) (2004) (0)
- Adhesion molecules in metastatic lesions of malignant melanoma: Immunohistological analysis (1992) (0)
- Reply: (2009) (0)
- Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice (2020) (0)
- Reply: To PMID 25132354. (2015) (0)
- miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury (2023) (0)
- Conference Article (0)
- Rosmarinic acid lifts PPAR gamma epigenetic repression and restores stellate cell quiescence via induction of MIR132 and MIR137 and suppression of MeCP2 and EZH2 (2010) (0)
- 3 Downregulation of Anti-Microbial Proteins Regenerating Islet-Derived 3 Beta (Reg3b) and Gamma (Reg3g) Contributes to Enteric Dysbiosis in Alcoholic Liver Disease (2010) (0)
- Tumor necrosis factor- (cid:1) inhibits peroxisome proliferator-activated receptor (cid:2) activity at a posttranslational level in hepatic stellate cells (2004) (0)
- Abstract 5357: TLR4-dependent Nanog+ cancer stem cells exhibit defective TGF-β signaling through IGF-Akt-Yap1 pathway (2010) (0)
- Abstract 1017: ProtooncogenicTLR4generates NANOG-dependent tumor-initiating stem-like cells through LIN28-Let7 pathway in experimental and clinical carcinogenesis (2012) (0)
- O039 : Circulating extracellular vesicles with specific proteome are novel biomarkers and therapeutic targets for alcoholic liver disease (2015) (0)
- TLR4 signaling induces hepatocellular carcinomas by synergistic interactions between alcohol and hepatitis C virus (2008) (0)
- Action plan for enhancing global collaboration on alcoholic liver and pancreatic diseases: White paper (2006) (0)
- 615 Epigenetic Regulation of iNOS, PPAR-Alpha, and Dnmt1 in the Cystathionine Beta Synthase Deficient Mouse Model of Alcoholic Steatohepatitis (2013) (0)
- ALPD 2015, Preface. (2015) (0)
- Abstract 1984: Cell fate reprogramming of liver tumor-initiating stem-like cells via phosphorylated NUMB and TBC1D15 (2018) (0)
- AKT ACTIVATION IN ALCOHOLIC PANCREATITIS: ROLE OF PTEN (2006) (0)
- Abstract 3594: The TGF-β effector β2SP depletion abrogates DNA damage repair (2016) (0)
- Center Overview (Special Issue July 2004: Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis Research Center--University of Southern California, Los Angeles, U.S.A.) (2004) (0)
- Novel NOTCH-Binding Protein Directs Self-Renewal of Tumor-Initiating Stem-like Cells and HCC Development through Cell Fate Reprogramming (2018) (0)
- Sa1954 Vitamin D Deficiency Promotes Hepatocellular Cancer via Regulating TLR7 in the Context of Loss of TGF-β/Smad3 (2015) (0)
- 769 Vitamin D As a Chemopreventive Agent for Hepatocellular Carcinoma in the Context of Impaired TGF-β? Signaling Pathway (2014) (0)
- Effects of sustained ethanol intoxication and optimal nutrition on free amino acid levels in plasma, liver and muscle of the rat (1988) (0)
- 1054 EXPRESSION PROFILING OF EPIGENETIC REGULATORS IDENTIFIES ASH1 AS A KEY ACTIVATOR OF PRO-FIBROGENIC GENES (2011) (0)
- Molecular characterization and tissue distribution of novel. Immunogenic melanoma-associated antigens sythesized in vitro (1993) (0)
- Active specific immunotherapy for malignant melanoma with allogeneic melanoma vaccine dynamics of immunological parameters along with clinical response (1993) (0)
- MOLECULAR BASIS FOR THE ROLE OF IRON IN EXPERIMENTAL ALCOHOLIC LIVER INJURY (1998) (0)
- Abstract 4111: Vitamin D for prevention of liver cancer in the setting of disrupted TGF-β signaling pathway (2014) (0)
- Epigenetic regulation of pro-fibrogenic genes involved in hepatic stellate cell activation and liver fibrosis (2010) (0)
- CONTRIBUTION OF MR. GLEN LEDGER TO DEVELOPMENT OF THE INTRAGASTRIC ETHANOL INFUSION MODEL (1998) (0)
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What Schools Are Affiliated With Hidekazu Tsukamoto?
Hidekazu Tsukamoto is affiliated with the following schools:
