Hideki Hasegawa
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Computer Science
Hideki Hasegawa's Degrees
- PhD Computer Science Imperial University of Japan
- Masters Computer Science Kyoto University
- Bachelors Computer Science Osaka University
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(Suggest an Edit or Addition)Hideki Hasegawa's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan (2013) (587)
- TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection (2019) (493)
- Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo. (2013) (463)
- Characterization of H7N9 influenza A viruses isolated from humans (2013) (392)
- Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I (2006) (282)
- Synthetic Double-Stranded RNA Poly(I:C) Combined with Mucosal Vaccine Protects against Influenza Virus Infection (2005) (252)
- Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant (2022) (211)
- Protection Against Influenza Virus Infection in Polymeric Ig Receptor Knockout Mice Immunized Intranasally with Adjuvant-Combined Vaccines (2002) (211)
- Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2 (2022) (152)
- Highly Frequent Mutations in Negative Regulators of Multiple Virulence Genes in Group A Streptococcal Toxic Shock Syndrome Isolates (2010) (151)
- The Host Protease TMPRSS2 Plays a Major Role in In Vivo Replication of Emerging H7N9 and Seasonal Influenza Viruses (2014) (138)
- Cross-Protection against H5N1 Influenza Virus Infection Is Afforded by Intranasal Inoculation with Seasonal Trivalent Inactivated Influenza Vaccine (2007) (132)
- Efficacy of T-705 (Favipiravir) in the Treatment of Infections with Lethal Severe Fever with Thrombocytopenia Syndrome Virus (2016) (119)
- A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets. (2017) (118)
- Effects of Toll-Like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-Inactivated Severe Acute Respiratory Syndrome-Related Coronavirus Vaccine (2014) (116)
- Characterization of Quasispecies of Pandemic 2009 Influenza A Virus (A/H1N1/2009) by De Novo Sequencing Using a Next-Generation DNA Sequencer (2010) (115)
- Mucosal IgA responses in influenza virus infections; thoughts for vaccine design. (2012) (112)
- Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs (2019) (111)
- Lethal Canine Distemper Virus Outbreak in Cynomolgus Monkeys in Japan in 2008 (2012) (110)
- Reducing the global burden of HTLV‐1 infection: An agenda for research and action (2017) (102)
- Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γcnull Mice: Suppression by an Inhibitor against NF-κB (2003) (100)
- Efficacy of Antibodies and Antiviral Drugs against Omicron BA.2.12.1, BA.4, and BA.5 Subvariants (2022) (99)
- Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2 (2022) (98)
- Differential localization of neurons susceptible to enterovirus 71 and poliovirus type 1 in the central nervous system of cynomolgus monkeys after intravenous inoculation. (2004) (96)
- Intranasal immunization with H5N1 vaccine plus Poly I:Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge. (2007) (95)
- Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses. (2009) (94)
- Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia. (2003) (93)
- Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia (2010) (92)
- Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus (2015) (92)
- Protective neutralizing influenza antibody response in the absence of T follicular helper cells (2016) (92)
- LC16m8, a Highly Attenuated Vaccinia Virus Vaccine Lacking Expression of the Membrane Protein B5R, Protects Monkeys from Monkeypox (2006) (91)
- Outer Membrane Vesicles of Porphyromonas gingivalis Elicit a Mucosal Immune Response (2011) (90)
- Mouse-Passaged Severe Acute Respiratory Syndrome-Associated Coronavirus Leads to Lethal Pulmonary Edema and Diffuse Alveolar Damage in Adult but Not Young Mice (2008) (86)
- Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets (2019) (85)
- A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells. (2018) (84)
- Type 2 diabetes impairs implant osseointegration capacity in rats. (2008) (82)
- Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential. (2014) (80)
- The first autopsy case of pandemic influenza (A/H1N1pdm) virus infection in Japan: detection of a high copy number of the virus in type II alveolar epithelial cells by pathological and virological examination. (2010) (77)
- An Attenuated LC16m8 Smallpox Vaccine: Analysis of Full-Genome Sequence and Induction of Immune Protection (2005) (76)
- Human-to-Human Transmission of Influenza A(H3N2) Virus with Reduced Susceptibility to Baloxavir, Japan, February 2019 (2019) (75)
- Distribution of PrP(Sc) in cattle with bovine spongiform encephalopathy slaughtered at abattoirs in Japan. (2006) (71)
- The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion (2016) (71)
- Two autopsy cases of severe fever with thrombocytopenia syndrome (SFTS) in Japan: A pathognomonic histological feature and unique complication of SFTS (2014) (71)
- Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus (2005) (69)
- Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice. (2009) (67)
- Virulence and pathophysiology of the Congo Basin and West African strains of monkeypox virus in non-human primates. (2009) (67)
- Increased risk of rhinovirus infection in children during the coronavirus disease‐19 pandemic (2021) (67)
- Spi-B is critical for plasmacytoid dendritic cell function and development. (2012) (65)
- Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2 (2022) (64)
- Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection (2012) (64)
- PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants. (2009) (63)
- Participation of both Host and Virus Factors in Induction of Severe Acute Respiratory Syndrome (SARS) in F344 Rats Infected with SARS Coronavirus (2006) (63)
- Severe Fever with Thrombocytopenia Syndrome, Japan, 2013–2017 (2020) (62)
- Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection. (2006) (62)
- Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak (2020) (61)
- Intranasal vaccination with an inactivated whole influenza virus vaccine induces strong antibody responses in serum and nasal mucus of healthy adults (2013) (59)
- Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null) mice: suppression by an inhibitor against NF-kappaB. (2003) (59)
- Identification and molecular characterization of a new nonsegmented double-stranded RNA virus isolated from Culex mosquitoes in Japan. (2011) (59)
- Canine Distemper Virus Associated with a Lethal Outbreak in Monkeys Can Readily Adapt To Use Human Receptors (2013) (58)
- Environmental Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 During a COVID-19 Outbreak on the Diamond Princess Cruise Ship (2020) (57)
- Severe Fever with Thrombocytopenia Syndrome Phlebovirus causes lethal viral hemorrhagic fever in cats (2019) (57)
- Protection against influenza virus infection by intranasal administration of C3d-fused hemagglutinin. (2003) (57)
- Syrian Hamster as an Animal Model for the Study of Human Influenza Virus Infection (2017) (56)
- Protection against influenza virus infection by intranasal administration of hemagglutinin vaccine with chitin microparticles as an adjuvant (2005) (55)
- Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine (2010) (53)
- Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma. (2009) (53)
- Human-herpesvirus-8-encoded K8 protein colocalizes with the promyelocytic leukemia protein (PML) bodies and recruits p53 to the PML bodies. (2001) (51)
- High-throughput gene expression analysis in bone healing around titanium implants by DNA microarray. (2008) (50)
- Vaccination-infection interval determines cross-neutralization potency to SARS-CoV-2 Omicron after breakthrough infection by other variants (2022) (47)
- Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam (2013) (47)
- Loop‐mediated isothermal amplification‐based diagnostic assay for monkeypox virus infections (2009) (44)
- Innate sensors of influenza virus: clues to developing better intranasal vaccines (2008) (44)
- Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections. (2020) (44)
- Intranasal administration of adjuvant‐combined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus (2010) (43)
- Combatting infectious diseases; nanotechnology as a platform for rational vaccine design. (2014) (42)
- Herpes Simplex Virus 1 VP22 Regulates Translocation of Multiple Viral and Cellular Proteins and Promotes Neurovirulence (2012) (42)
- Profile of Exosomal and Intracellular microRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines (2016) (41)
- Induction of cross‐protective immunity against influenza A virus H5N1 by an intranasal vaccine with extracts of mushroom mycelia (2010) (39)
- The Pathogenesis of 3 Neurotropic Flaviviruses in a Mouse Model Depends on the Route of Neuroinvasion After Viremia (2015) (38)
- IgA polymerization contributes to efficient virus neutralization on human upper respiratory mucosa after intranasal inactivated influenza vaccine administration (2018) (38)
- The road to a more effective influenza vaccine: Up to date studies and future prospects. (2017) (38)
- An assessment of real-time RT-PCR kits for SARS-CoV-2 detection. (2020) (38)
- An Endoplasmic Reticulum Protein, p180, Is Highly Expressed in Human Cytomegalovirus-Permissive Cells and Interacts with the Tegument Protein Encoded by UL48 (2002) (37)
- Severe Fever with Thrombocytopenia Syndrome Virus Antigen Detection Using Monoclonal Antibodies to the Nucleocapsid Protein (2016) (36)
- Diagnosis and assessment of monkeypox virus (MPXV) infection by quantitative PCR assay: differentiation of Congo Basin and West African MPXV strains. (2008) (36)
- Cross‐reactive antigenicity of nucleoproteins of lyssaviruses recognized by a monospecific antirabies virus nucleoprotein antiserum on paraffin sections of formalin‐fixed tissues (2003) (36)
- Association of Major Histocompatibility Complex Class I Haplotypes with Disease Progression after Simian Immunodeficiency Virus Challenge in Burmese Rhesus Macaques (2012) (35)
- Excessive Cytokine Response to Rapid Proliferation of Highly Pathogenic Avian Influenza Viruses Leads to Fatal Systemic Capillary Leakage in Chickens (2013) (35)
- Preclinical efficacy of the synthetic retinoid ST1926 for treating adult T-cell leukemia/lymphoma. (2014) (34)
- Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus (2019) (33)
- A patient with severe fever with thrombocytopenia syndrome and hemophagocytic lymphohistiocytosis-associated involvement of the central nervous system. (2017) (33)
- Functional and structural characteristics of secretory IgA antibodies elicited by mucosal vaccines against influenza virus. (2017) (33)
- Viroporin activity of the JC polyomavirus is regulated by interactions with the adaptor protein complex 3 (2013) (33)
- Nucleolin and the Packaging Signal, ψ, Promote the Budding of Human Immunodeficiency Virus Type‐1 (HIV‐1) (2004) (33)
- Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine? (2016) (33)
- IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody (2019) (33)
- Next‐generation sequencing of miRNAs in clinical samples of Epstein–Barr virus‐associated B‐cell lymphomas (2017) (32)
- Neutrophil Depletion Suppresses Pulmonary Vascular Hyperpermeability and Occurrence of Pulmonary Edema Caused by Hantavirus Infection in C.B-17 SCID Mice (2014) (32)
- Transcriptional Activation of JC Virus by Human T-lymphotropic Virus Type I Tax Protein in Human Neuronal Cell Lines* (2000) (31)
- Frequent detection of Merkel cell polyomavirus DNA in sera of HIV-1-positive patients (2013) (31)
- Screening transplant donors for HTLV-1 and -2. (2016) (31)
- Protection against influenza virus infection by intranasal vaccine with surf clam microparticles (SMP) as an adjuvant (2006) (31)
- A Mutant H3N2 Influenza Virus Uses an Alternative Activation Mechanism in TMPRSS2 Knockout Mice by Loss of an Oligosaccharide in the Hemagglutinin Stalk Region (2015) (31)
- Assessment of outer membrane vesicles of periodontopathic bacterium Porphyromonas gingivalis as possible mucosal immunogen. (2016) (30)
- Combination Therapy With Neuraminidase and Polymerase Inhibitors in Nude Mice Infected With Influenza Virus (2018) (30)
- Characterization of a Feline Influenza A(H7N2) Virus (2018) (30)
- Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic (2007) (29)
- Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Returnees to Japan from Wuhan, China, 2020 (2020) (29)
- Mucosal Immunization and Adjuvants (2014) (29)
- Plasma 25-Hydroxyvitamin D Is Independently Associated with Hemoglobin Concentration in Male Subjects with Type 2 Diabetes Mellitus (2011) (29)
- Pathology of Kaposi’s Sarcoma-Associated Herpesvirus Infection (2011) (28)
- Classification of AIDS-related lymphoma cases between 1987 and 2012 in Japan based on the WHO classification of lymphomas, fourth edition (2014) (28)
- The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan (2014) (27)
- A Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito, Pretreatment in Mice Prevented Influenza Virus Replication Accompanied with GM-CSF Expression and Increase in Several Defensin mRNA Levels (2013) (27)
- Environmental sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during a coronavirus disease (COVID-19) outbreak aboard a commercial cruise ship (2020) (27)
- Intranasal Administration of Whole Inactivated Influenza Virus Vaccine as a Promising Influenza Vaccine Candidate. (2017) (27)
- Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests (2021) (26)
- Development of oligomannose-coated liposome-based nasal vaccine against human parainfluenza virus type 3 (2013) (25)
- Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice. (2009) (25)
- Estimation of the effective doses of nasal-inactivated influenza vaccine in humans from mouse-model experiments. (2010) (25)
- Development of mucosal adjuvants for intranasal vaccine for H5N1 influenza viruses (2009) (25)
- Evaluation of the effectiveness and safety of chitosan derivatives as adjuvants for intranasal vaccines. (2013) (25)
- Role of JC virus agnoprotein in virion formation (2012) (24)
- Identification of a Varicella-Zoster Virus Replication Inhibitor That Blocks Capsid Assembly by Interacting with the Floor Domain of the Major Capsid Protein (2012) (24)
- Development of a new real-time PCR system for simultaneous detection of bacteria and fungi in pathological samples. (2015) (24)
- Rabies virus dissemination in neural tissues of autopsy cases due to rabies imported into Japan from the Philippines: Immunohistochemistry (2009) (24)
- Mobile and accurate detection system for infection by the 2009 pandemic influenza A (H1N1) virus with a pocket‐warmer reverse‐transcriptase loop‐mediated isothermal amplification (2011) (23)
- Passive immune-prophylaxis against influenza virus infection by the expression of neutralizing anti-hemagglutinin monoclonal antibodies from plasmids. (2011) (23)
- Pathological Characteristics of a Patient with Severe Fever with Thrombocytopenia Syndrome (SFTS) Infected with SFTS Virus through a Sick Cat’s Bite (2021) (23)
- Mechanism of drug resistance of hemagglutinin of influenza virus and potent scaffolds inhibiting its function. (2012) (23)
- The effect of mucoadhesive excipient on the nasal retention time of and the antibody responses induced by an intranasal influenza vaccine. (2016) (22)
- Sudden death of a patient with pandemic influenza (A/H1N1pdm) virus infection by acute respiratory distress syndrome. (2010) (22)
- A Single Vaccination of Nonhuman Primates with Highly Attenuated Smallpox Vaccine, LC16m8, Provides Long-term Protection against Monkeypox. (2017) (22)
- Human immune responses elicited by an intranasal inactivated H5 influenza vaccine (2020) (22)
- An autopsy case of Balamuthia mandrillaris amoebic encephalitis, a rare emerging infectious disease, with a brief review of the cases reported in Japan (2015) (21)
- Tristetraprolin inhibits HIV-1 production by binding to genomic RNA. (2006) (21)
- Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies (2019) (20)
- Induction of protective immunity against severe acute respiratory syndrome coronavirus (SARS-CoV) infection using highly attenuated recombinant vaccinia virus DIs (2006) (20)
- Neutralizing antibody against severe acute respiratory syndrome (SARS)‐coronavirus spike is highly effective for the protection of mice in the murine SARS model (2008) (19)
- TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus (2016) (19)
- Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014 (2016) (19)
- Analysis of bronchoalveolar lavage fluid in a mouse model of bronchial asthma and H1N1 2009 infection. (2013) (19)
- Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System (2016) (18)
- Candidatus Mycoplasma haemohominis in Human, Japan (2020) (18)
- Deep-Sequence Identification and Role in Virus Replication of a JC Virus Quasispecies in Patients with Progressive Multifocal Leukoencephalopathy (2016) (18)
- Effects of the number of amino acid residues in the signal segment upstream or downstream of the NS2B-3 cleavage site on production and secretion of prM/M-E virus-like particles of West Nile virus. (2009) (18)
- Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution (2020) (18)
- Prophylactic effects of chitin microparticles on highly pathogenic H5N1 influenza virus (2007) (18)
- Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach (2021) (18)
- Pathogenesis of fulminant monkeypox with bacterial sepsis after experimental infection with West African monkeypox virus in a cynomolgus monkey. (2014) (17)
- Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles (2020) (17)
- Shape-dependent adjuvanticity of nanoparticle-conjugated RNA adjuvants for intranasal inactivated influenza vaccines (2018) (17)
- Intranasal inactivated influenza vaccines for the prevention of seasonal influenza epidemics (2018) (17)
- The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route (2018) (17)
- An outbreak of histoplasmosis among healthy young Japanese women after traveling to Southeast Asia. (2010) (17)
- Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated influenza vaccine (2012) (17)
- Seroprevalence of trichodysplasia spinulosa-associated polyomavirus in Japan. (2015) (17)
- The Microminipig as an Animal Model for Influenza A Virus Infection (2016) (16)
- Evidence for human herpesvirus-6B infection of regulatory T-cells in acute systemic lymphadenitis in an immunocompetent adult with the drug reaction with eosinophilia and systemic symptoms syndrome: a case report. (2014) (16)
- Pathology and virus dispersion in cynomolgus monkeys experimentally infected with severe acute respiratory syndrome coronavirus via different inoculation routes (2007) (16)
- A lethal mouse model for evaluating vaccine-associated enhanced respiratory disease during SARS-CoV-2 infection (2022) (16)
- High diversity of HHV‐8 molecular subtypes in the Amazon region of Brazil: Evidence of an ancient human infection (2007) (16)
- Zika virus protease induces caspase-independent pyroptotic cell death by directly cleaving gasdermin D. (2020) (15)
- Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques (2017) (15)
- Genome Recombination between Delta and Alpha Variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (2021) (15)
- Human topoisomerase I promotes HIV-1 proviral DNA synthesis: Implications for the species specificity and cellular tropism of HIV-1 infection (2003) (15)
- Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targets (2017) (15)
- cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue (2017) (14)
- BCL-6-positive Human Herpesvirus 8-associated Solid Lymphoma Arising from Liver and Spleen as Multiple Nodular Lesions (2004) (13)
- A case of X-linked agammaglobulinemia with progressive encephalitis. (2004) (13)
- Influenza A(H1N1)pdm09 virus exhibiting reduced susceptibility to baloxavir due to a PA E23K substitution detected from a child without baloxavir treatment. (2020) (13)
- A Glycolipid Adjuvant, 7DW8-5, Enhances the Protective Immune Response to the Current Split Influenza Vaccine in Mice (2019) (13)
- Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells (2021) (13)
- Protection against influenza virus infection by nasal vaccination in advance of sublethal irradiation. (2000) (13)
- Dicer and positive charge of proteins decrease the stability of RNA containing the AU-rich element of GM-CSF. (2006) (13)
- Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection. (2014) (12)
- Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan (2015) (12)
- Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi’s sarcoma–associated herpesvirus (2016) (12)
- Potency of gastrointestinal colonization and virulence of Candida auris in a murine endogenous candidiasis (2020) (12)
- Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2 (2022) (12)
- Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron BA.1 in Syrian hamsters (2022) (12)
- Pathogenic characterization of a cervical lymph node derived from a patient with Kawasaki disease. (2012) (12)
- Detection of trichodysplasia spinulosa-associated polyomavirus in a fatal case of myocarditis in a seven-month-old girl. (2014) (11)
- Efficacy of Antiviral Agents against the Omicron Subvariant BA.2.75 (2022) (11)
- Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus (2014) (11)
- CpG ODN G9.1 as a novel nasal ODN adjuvant elicits complete protection from influenza virus infection without causing inflammatory immune responses. (2019) (11)
- Topoisomerase I and ATP activate cDNA synthesis of human immunodeficiency virus type 1. (2002) (11)
- Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection (2012) (11)
- NS1-binding protein abrogates the elevation of cell viability by the influenza A virus NS1 protein in association with CRKL. (2013) (11)
- High expression of JC polyomavirus-encoded microRNAs in progressive multifocal leukoencephalopathy tissues and its repressive role in virus replication (2020) (10)
- Hochuekkito, a Japanese Herbal Medicine, Restores Metabolic Homeostasis between Mitochondrial and Glycolytic Pathways Impaired by Influenza A Virus Infection (2017) (10)
- Transient Appearance of Plasmablasts in the Peripheral Blood of Japanese Patients With Severe Fever With Thrombocytopenia Syndrome. (2019) (10)
- Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection (2017) (10)
- Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection (2018) (10)
- Serial Section Array Scanning Electron Microscopy Analysis of Cells from Lung Autopsy Specimens following Fatal A/H1N1 2009 Pandemic Influenza Virus Infection (2019) (10)
- Accumulation of cellular prion protein within β‐amyloid oligomer plaques in aged human brains (2021) (10)
- Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection (2017) (10)
- Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models (2016) (10)
- Early mortality following intracerebral infection with the Oshima strain of tick-borne encephalitis virus in a mouse model. (2010) (10)
- Experimental infection of Cynomolgus Macaques with highly pathogenic H5N1 influenza virus through the aerosol route (2018) (9)
- Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells (2021) (8)
- Conserved sequences of BART and BHRF regions encoding viral microRNAs in Epstein-Barr virus-associated lymphoma (2017) (8)
- Fumagillin, a potent angiogenesis inhibitor, induces Kaposi sarcoma-associated herpesvirus replication in primary effusion lymphoma cells. (2015) (8)
- Unusual manifestation of disseminated herpes simplex virus type 2 infection associated with pharyngotonsilitis, esophagitis, and hemophagocytic lymphohisitocytosis without genital involvement (2019) (8)
- Acute liver failure associated with influenza A virus infection: an autopsy case report. (2019) (8)
- Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice (2017) (8)
- Topoisomerase I dissociates human immunodeficiency virus type 1 reverse transcriptase from genomic RNAs. (2004) (7)
- Reconstitution of cleavage of human immunodeficiency virus type-1 (HIV-1) RNAs. (2002) (7)
- Functional analysis of an alpha-helical antimicrobial peptide derived from a novel mouse defensin-like gene. (2010) (7)
- A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase. (2011) (7)
- Comparison of acellular pertussis-based combination vaccines by Japanese control tests for toxicities and laboratory models for local reaction. (2009) (7)
- In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6 (2022) (7)
- Unusual presentation of a severely ill patient having severe fever with thrombocytopenia syndrome: a case report (2017) (7)
- Induction of lung CD8+ T cell responses by consecutive inoculations of a poly(I:C) influenza vaccine. (2017) (7)
- Binding and dissociation of human topoisomerase I with hairpin-loop RNAs: implications for the regulation of HIV-1 replication. (2002) (7)
- Establishment of a panel of in‐house polyclonal antibodies for the diagnosis of enterovirus infections (2014) (7)
- The Preventive Effect of the Traditional Japanese Herbal Medicine, Hochuekkito, against Influenza A Virus via Autophagy in vitro (2016) (7)
- Cytokine and growth factor expression by HTLV-1 Lck-tax transgenic cells in SCID mice. (2010) (6)
- SARS-CoV-2 antigen rapid diagnostic test enhanced with silver amplification technology (2021) (6)
- Immunogenicity and protective efficacy of SARS-CoV-2 recombinant S-protein vaccine S-268019-b in cynomolgus monkeys (2022) (6)
- Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils (2018) (6)
- Immune reconstitution inflammatory syndrome associated with Kaposi’s sarcoma: successful treatment with interferon-α (2007) (5)
- 2019 meeting of the global virus network (2019) (5)
- Identification and characterization of a novel Enterococcus bacteriophage with potential to ameliorate murine colitis (2021) (5)
- A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period (2014) (5)
- Virus-infected peripheral blood plasmablasts in a patient with severe fever with thrombocytopenia syndrome (2020) (5)
- Cross-protective immunity against influenza virus infections induced by intranasal vaccination together with a TLR3-mucosal adjuvant (2011) (5)
- Intranasal vaccination with HBs and HBc protein combined with carboxyl vinyl polymer induces strong neutralizing antibody, anti-HBs IgA, and IFNG response. (2019) (5)
- Herpes encephalitis and paraneoplastic limbic encephalitis (1998) (5)
- Suberoyl Bis-Hydroxamic Acid Reactivates Kaposi’s Sarcoma-Associated Herpesvirus through Histone Acetylation and Induces Apoptosis in Lymphoma Cells (2020) (5)
- Processing of the HTLV-II envelope precursor glycoprotein gp63 by furin is essential for cell fusion activity. (2002) (5)
- 2017 international meeting of the Global Virus Network (2018) (5)
- Effects of Toll-like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c 1 (2014) (5)
- Development of highly sensitive and rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor (2021) (4)
- Evaluation of Vero-cell-derived simian endogenous retrovirus infection in humans by detection of viral genome in clinicopathological samples and commercialized vaccines and by serology of Japanese general population. (2016) (4)
- Application of HTLV-1 tax transgenic mice for therapeutic intervention. (2018) (4)
- Preclinical ef fi cacy of the synthetic retinoid ST 1926 for treating adult T-cell leukemia / lymphoma (2014) (4)
- M-Sec induced by HTLV-1 mediates an efficient viral transmission (2021) (4)
- Functional analysis of trichodysplasia spinulosa-associated polyomavirus-encoded large T antigen. (2019) (4)
- Robust production of IL-33 and TSLP by lung endothelial cells in response to dsRNA stimulation. (2020) (4)
- Pathogenesis of influenza A(H7N9) virus in aged non-human primates. (2020) (4)
- Mechanism of Action of the Anti-Influenza Virus Active Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito (2017) (4)
- Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses (2019) (4)
- 2016 International meeting of the Global Virus Network (2017) (4)
- The peripheral T cell population is associated with pneumonia severity in cynomolgus monkeys experimentally infected with severe acute respiratory syndrome coronavirus 2 (2021) (3)
- Highly Attenuated Vaccinia Virus Dis as a Potential Sars Vaccine (2006) (3)
- Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8+ T-cell frequencies in a macaque AIDS model (2016) (3)
- Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing. (2019) (3)
- Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma: successful treatment with interferon-alpha. (2007) (3)
- Corrigendum to: Environmental Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 During a COVID-19 Outbreak on the Diamond Princess Cruise Ship (2020) (3)
- Cutaneous histopathology of the tick‐bite region in severe fever with thrombocytopenia syndrome (2019) (3)
- Detection of Influenza Virus with Specific Subtype by Using Localized Surface Plasmons Excited on a Flat Metal Surface (2013) (3)
- Non Susceptibility of Neonatal and Adult Rats against the Middle East Respiratory Syndrome Coronavirus. (2016) (3)
- Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology (2022) (3)
- An influenza HA stalk reactive polymeric IgA antibody exhibits anti-viral function regulated by binary interaction between HA and the antibody (2021) (2)
- Enhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection (2020) (2)
- A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza (2020) (2)
- Knowledge Obtained from an Elderly Case of Japanese Encephalitis. (2016) (2)
- Development of Corona-virus-disease-19 Vaccines (2021) (2)
- Different Starting Dominant Strain of Seasonal Influenza in China and Other Neighboring Asian Countries in 2019−2020 Winter Season (2020) (2)
- Protective antibody responses against A(H1N1)pdm09 primed by infection and recalled by intranasal vaccination. (2015) (2)
- Histopathological Findings of Lung with A/H1N1pdm09 Infection-Associated Acute Respiratory Distress Syndrome in the Post-Pandemic Season. (2017) (2)
- Immune response and protective efficacy of the SARS-CoV-2 recombinant spike protein vaccine S-268019-b in mice (2022) (2)
- Next-Generation Sequencing Analysis of the Within-Host Genetic Diversity of Influenza A(H1N1)pdm09 Viruses in the Upper and Lower Respiratory Tracts of Patients with Severe Influenza (2021) (2)
- Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses (2021) (2)
- Intracerebral Inoculation of Mouse-Passaged Saffold Virus Type 3 Affects Cerebellar Development in Neonatal Mice (2016) (2)
- Persistent infection of influenza virus in irradiated mice and its prevention by intranasal vaccination. (2002) (2)
- Pathological Characteristics of Severe Fever With Thrombocytopenia Syndrome (SFTS) Virus in a Patient Infected With Sfts Virus From a Sick Cat’s Bite (2021) (1)
- Epidemiology and Genetic Analysis of SARS-CoV-2 in Myanmar during the Community Outbreaks in 2020 (2022) (1)
- Sasaki, I. et al. Spi-B is crucial for plasmacytoid dendritic cell function and development. Blood 120, 4733-4743 (2012) (1)
- Highly Specific Monoclonal Antibodies Against SARS-CoV-2 Nucleocapsid Antigen for Accurate Diagnosis of COVID-19 (2020) (1)
- A case of Epstein–Barr virus‐associated lymphoepithelioma‐like carcinoma of the colon (2021) (1)
- Prophylactic Vaccine Targeting TLR3 on Dendritic Cells Ameliorates Eosinophilic Pneumonia in a Mouse SARS-CoV Infection Model (2022) (1)
- Double-Stranded Structure of the Polyinosinic-Polycytidylic Acid Molecule to Elicit TLR3 Signaling and Adjuvant Activity in Murine Intranasal A(H1N1)pdm09 Influenza Vaccination. (2020) (1)
- Antiviral susceptibilities of avian influenza A(H5), A(H7), and A(H9) viruses isolated in Japan. (2021) (1)
- Plasma Exchange Did Not Reduce Viral Load in a Recovered Case of Severe Fever with Thrombocytopenia Syndrome (2021) (1)
- Inefficient Tax-specific T-cell responses in mice after syngeneic transplantation with tax-transgenic mouse-derived adult T-cell leukemia cells. (2020) (1)
- Monoclonal antibody and siRNAs for topoisomerase I suppress telomerase activity. (2009) (1)
- Post-Exposure Vaccination with a Highly Attenuated Vaccinia Vaccine, LC16m8, for Protection of Nonhuman Primates from Monkeypox (2008) (1)
- Short Communication Virulence and pathophysiology of the Congo Basin and West African strains of monkeypox virus in non-human primates (2009) (1)
- Propagation of activated B cells by in vitro SFTSV infection of human peripheral blood mononuclear cells. (2021) (1)
- Meningeal large granular lymphocyte lymphoma (1998) (1)
- Detection of a peramivir-resistant influenza B/Yamagata-lineage virus imported from Indonesia in Aichi, Japan, March 2019. (2020) (1)
- Neuropathology in Neonatal Mice After Experimental Coxsackievirus B2 Infection Using a Prototype Strain, Ohio-1. (2019) (1)
- Comparative proteomic analysis of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma (2011) (1)
- Dry loop mediated isothermal amplification assay for detection of SARS-CoV-2 from clinical specimens (2020) (1)
- Frequent detection of Merkel cell polyomavirus DNA in sera of HIV-1-positive patients (2013) (1)
- Identification and analysis of commensal bacteriophage in the intestine (2017) (0)
- The Osteoclast Targeting Therapy In Bone Metastasis For a Mouse Model Of Adult T Cell Leukemia (2013) (0)
- Antiviral Susceptibilities of Distinct Lineages of Influenza C and D Viruses (2023) (0)
- Pathological and Virological Analyses of Severe Acute Respiratory Syndrome–Associated Coronavirus Infections in Experimantal Animals (2006) (0)
- When to update COVID-19 vaccine composition (2023) (0)
- Development of a Monoclonal Antibody Targeting HTLV-1 Envelope gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy (2022) (0)
- Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targets (2017) (0)
- Analysis of HTLV-II syncytium formation using recombinant cowpoxvirus expressing the evelope precursor glycoprotein,gp63. (1999) (0)
- Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection (2017) (0)
- Identification of Leukemic Stem Cells and Their Niche in Adult T Cell Leukemia Using the Tax-Transgenic Mouse Model (2012) (0)
- 130 Reinhard Kurth Honorary Lecture HTLV-I and Adult T Cell Leukemia/Lymphoma (ATLL): Cellular and Molecular Basis of Transformation (2014) (0)
- Infection Model Ameliorates Eosinophilic Pneumonia in a Mouse SARS-CoV Prophylactic Vaccine Targeting TLR3 on Dendritic Cells (2022) (0)
- A fatal case of hemophagocytic lymphohistiocytosis associated with gestational psittacosis without symptoms of pneumonia (2022) (0)
- Contents Vol. 91, 2013 (2013) (0)
- Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia (2015) (0)
- Detection of influenza viruses by localized surface plasmon sensing (2009) (0)
- Results from a preclinical study in rodents and a Phase 1/2, randomized, double-blind, placebo-controlled, parallel-group study of COVID-19 vaccine S-268019-a in Japanese adults (2022) (0)
- The Combination of Arsenic Trioxide and Interferon-Alpha Eradicates Leukemia Initiating Cells in TAX-Driven Murine Adult T Cell Leukemia/Lymphoma. (2009) (0)
- Identification of Serum Prognostic Biomarkers of Severe COVID-19 by Quantitative Proteomic Approach (2021) (0)
- Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils (2018) (0)
- Covalent bonded Gag multimers in human immunodeficiency virus type‐1 particles (2009) (0)
- Impact of Reinfection with SARS-CoV-2 Omicron Variants in Previously Infected Hamsters (2022) (0)
- Enhanced airway hyperresponsiveness in a mouse model of asthma with A(H1N1)pdm09 infection (2020) (0)
- High Expression of Polyomavirus-Encoded MicroRNAs in Progressive Multifocal Leukoencephalopathy and BK Polyomavirus-Associated Nephropathy Tissues, and Their Repressive Role in Virus Replication (2019) (0)
- Cytomegalic Inclusion Disease caused by Cytomegalovirus Infection in the Salivary Glands of an African Hedgehog (Atelerix arbiventris). (2017) (0)
- Targeted Therapy with Arsenic Trioxide and Interferon alpha Eradicates Leukemic Cells in SCID Mice Model of Adult T-Cell Leukemia/Lymphoma. (2007) (0)
- Advance Publication by J-STAGE Japanese Journal of Infectious Diseases Functional analysis of trichodysplasia spinulosa-associated polyomavirus-encoded large T antigen (2019) (0)
- SARS virus and pathology of SARS (2003) (0)
- Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi’s sarcoma–associated herpesvirus (2016) (0)
- Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection (2022) (0)
- Identification of the properties of H5 influenza vaccine viruses with high hemagglutinin yields (2023) (0)
- , H 7 N 9 and Seasonal Influenza Viruses Replication of Emerging In Vivo Role in The Host Protease TMPRSS 2 Plays a Major (2014) (0)
- Development of A Localized Surface Plasmon Sensor with A Fabricated Sensing Surface Toward Multi-Analyte Detection (2016) (0)
- Saturation time of exposure interval for cross-neutralization response to SARS-CoV-2: Implications for vaccine dose interval (2023) (0)
- Contents Vol. 99, 2017 (2017) (0)
- Use of the particle agglutination/particle agglutination inhibition test for antigenic analysis of SARS‐CoV‐2 (2022) (0)
- Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets (2019) (0)
- adjuvanticity of nanoparticle-conjugated RNA adjuvants for intranasal inactivated in fl uenza vaccines † (2018) (0)
- Conserved sequences of BART and BHRF regions encoding viral microRNAs in Epstein-Barr virus-associated lymphoma (2017) (0)
- Supplementary Material for: The Preventive Effect of the Traditional Japanese Herbal Medicine, Hochuekkito, against Influenza A Virus via Autophagy in vitro (2016) (0)
- Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia (2015) (0)
- Supplementary Material for: Hochuekkito, a Japanese Herbal Medicine, Restores Metabolic Homeostasis between Mitochondrial and Glycolytic Pathways Impaired by Influenza A Virus Infection (2017) (0)
- Adjuvant-Combined Vaccines Immunized Intranasally with in Polymeric Ig Receptor Knockout Mice Protection Against Influenza Virus Infection (2002) (0)
- Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma (2009) (0)
- Development of the vaccine of coronavirus which assumed gold nanoparticles as adjuvant (2017) (0)
- Experimental infection of Cynomolgus Macaques with highly pathogenic H5N1 influenza virus through the aerosol route (2018) (0)
- The Loop-Mediated Isothermal Amplification-Based Diagnostics for Monkeypox Virus Infection (2008) (0)
- Molecular Analysis of Phosphorylated Tyrosine-Binding Proteins in the Transduction of Proliferation and Differentiation Signals (1996) (0)
- Method for preventing influenza using a vaccine for intranasal administration (2010) (0)
- Suitability of NIID‐MDCK cells as a substrate for cell‐based influenza vaccine development from the perspective of adventitious virus susceptibility (2022) (0)
- Cytokine Profiles In Bronchoalveolar Lavage In a Mouse Model Of Bronchial Asthma During A(H1N1)pdm09 and Seasonal H1N1 Infection (2014) (0)
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What Schools Are Affiliated With Hideki Hasegawa?
Hideki Hasegawa is affiliated with the following schools:
