Hideo Kimura
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Computer Science
Hideo Kimura's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Hideo Kimura's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The possible role of hydrogen sulfide as an endogenous neuromodulator (1996) (1844)
- The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. (1997) (1149)
- Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function (2007) (1010)
- Mechanism of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction (1997) (996)
- 3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. (2009) (799)
- Hydrogen sulfide protects neurons from oxidative stress (2004) (773)
- Brain hydrogen sulfide is severely decreased in Alzheimer's disease. (2002) (663)
- Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. (2010) (588)
- Development of a highly selective fluorescence probe for hydrogen sulfide. (2011) (563)
- Hydrogen sulfide: its production, release and functions (2011) (484)
- Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. (2000) (459)
- A source of hydrogen sulfide and a mechanism of its release in the brain. (2009) (444)
- Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. (2009) (438)
- A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells (2013) (407)
- Amyloid peptides are toxic via a common oxidative mechanism. (1995) (389)
- Hydrogen sulfide as a neuromodulator (2002) (368)
- Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor. (2000) (329)
- Hydrogen sulfide protects HT22 neuronal cells from oxidative stress. (2006) (298)
- Hydrogen sulfide induces calcium waves in astrocytes (2004) (298)
- Activin is a nerve cell survival molecule (1990) (297)
- Hydrogen sulfide: from brain to gut. (2010) (282)
- Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. (2004) (281)
- Polysulfides are possible H2S‐derived signaling molecules in rat brain (2013) (275)
- Identification of Hypoxia-inducible Factor 1 Ancillary Sequence and Its Function in Vascular Endothelial Growth Factor Gene Induction by Hypoxia and Nitric Oxide* (2001) (274)
- Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. (2003) (253)
- L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter. (2006) (250)
- Production and physiological effects of hydrogen sulfide. (2014) (247)
- Hydrogen sulfide is a signaling molecule and a cytoprotectant. (2012) (242)
- The physiological role of hydrogen sulfide and beyond. (2014) (240)
- Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide. (2011) (227)
- Physiological role of hydrogen sulfide and polysulfide in the central nervous system (2013) (223)
- Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. (2006) (222)
- Physiological roles of hydrogen sulfide: synaptic modulation, neuroprotection, and smooth muscle relaxation. (2005) (215)
- Cystathionine β‐synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS (2005) (207)
- Hydrogen Sulfide Is Produced in Response to Neuronal Excitation (2002) (171)
- Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain (2015) (161)
- Growth factors and vitamin E modify neuronal glutamate toxicity. (1992) (159)
- Hydrogen sulfide: its production and functions (2011) (148)
- Structure, expression and function of a schwannoma-derived growth factor (1990) (148)
- Abnormal Lipid Metabolism in Cystathionine β-Synthase-deficient Mice, an Animal Model for Hyperhomocysteinemia* (2004) (148)
- Polysulfide exerts a protective effect against cytotoxicity caused by t‐buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells (2013) (148)
- Signaling molecules: hydrogen sulfide and polysulfide. (2015) (146)
- Hydrogen Sulfide and Polysulfides as Biological Mediators (2014) (124)
- Hydrogen Sulfide Protects the Retina from Light-induced Degeneration by the Modulation of Ca2+ Influx* (2011) (123)
- Cystathionine β-synthase is enriched in the brains of Down’s patients (2005) (108)
- Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice. (2012) (102)
- Glucose‐induced production of hydrogen sulfide may protect the pancreatic beta‐cells from apoptotic cell death by high glucose (2009) (97)
- Hydrogen sulfide and polysulfides as signaling molecules (2015) (93)
- 3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S (2017) (90)
- Polysulfides (H2Sn) produced from the interaction of hydrogen sulfide (H2S) and nitric oxide (NO) activate TRPA1 channels (2017) (89)
- MOCA Induces Membrane Spreading by Activating Rac1* (2004) (87)
- A Novel Enhancing Mechanism for Hydrogen Sulfide-producing Activity of Cystathionine β-Synthase* (2002) (82)
- Schwannoma-derived growth factor must be transported into the nucleus to exert its mitogenic activity. (1993) (82)
- Physiological Roles of Hydrogen Sulfide and Polysulfides. (2015) (77)
- Amyloid β Toxicity Consists of a Ca2+‐Independent Early Phase and a Ca2+‐Dependent Late Phase (1996) (73)
- Cystathionine beta-synthase is enriched in the brains of Down's patients. (2005) (68)
- Autotaxin expression is enhanced in frontal cortex of Alzheimer-type dementia patients (2006) (67)
- A novel mechanism for the regulation of amyloid precursor protein metabolism (2002) (64)
- The production of hydrogen sulfide is regulated by testosterone and S‐adenosyl‐l‐methionine in mouse brain (2002) (61)
- Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide (2017) (61)
- Production of Hydrogen Sulfide from D-Cysteine and Its Therapeutic Potential (2013) (60)
- Signalling by hydrogen sulfide and polysulfides via protein S‐sulfuration (2020) (56)
- Substratum-growth factor collaborations are required for the mitogenic activities of activin and FGF on embryonal carcinoma cells (1991) (56)
- Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons (2015) (55)
- Hydrogen sulfide is produced by cystathionine γ-lyase at the steady-state low intracellular Ca(2+) concentrations. (2013) (55)
- Signaling by hydrogen sulfide (H2S) and polysulfides (H2Sn) in the central nervous system (2019) (54)
- Signaling of hydrogen sulfide and polysulfides. (2015) (53)
- Analysis of endogenous H2S and H2Sn in mouse brain by high‐performance liquid chromatography with fluorescence and tandem mass spectrometric detection (2017) (48)
- Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application. (2017) (48)
- Effects of nitric oxide donors on vascular endothelial growth factor gene induction. (2002) (47)
- Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate. (1993) (46)
- Metabolic Turnover of Hydrogen Sulfide (2012) (45)
- Hydrogen polysulfide (H2Sn) signaling along with hydrogen sulfide (H2S) and nitric oxide (NO) (2016) (44)
- Schwannoma-derived growth factor promotes the neuronal differentiation and survival of PC12 cells (1992) (43)
- Hydrogen Sulfide (H2S) and Polysulfide (H2Sn) Signaling: The First 25 Years (2021) (42)
- Alternative pathway of H2S and polysulfides production from sulfurated catalytic-cysteine of reaction intermediates of 3-mercaptopyruvate sulfurtransferase. (2018) (40)
- Two Novel Xenopus Homologs of Mammalian LPA1/EDG-2 Function as Lysophosphatidic Acid Receptors inXenopus Oocytes and Mammalian Cells* (2001) (37)
- Cadmium exposure alters metabolomics of sulfur-containing amino acids in rat testes. (2005) (37)
- Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology (2019) (37)
- Hydrogen sulfide enhances reducing activity in neurons: neurotrophic role of H2S in the brain? (2007) (35)
- Sulfite protects neurons from oxidative stress (2018) (33)
- Determination of oxidized and reduced nicotinamide adenine dinucleotide in cell monolayers using a single extraction procedure and a spectrophotometric assay. (2005) (33)
- Amyloid beta toxicity consists of a Ca(2+)-independent early phase and a Ca(2+)-dependent late phase. (1996) (25)
- Differentiated astrocytes acquire sensitivity to hydrogen sulfide that is diminished by the transformation into reactive astrocytes. (2006) (24)
- Hydrogen Sulfide and Polysulfide Signaling. (2017) (24)
- Polysulfide activates TRP channels and increases intracellular Ca2+ in astrocytes (2010) (21)
- The production of hydrogen sulfide is regulated by testosterone and S‐adenosyl‐l‐methionine in mouse brain (2005) (20)
- Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell (2012) (19)
- Presenilin‐binding protein forms aggresomes in monkey kidney COS‐7 cells (2002) (19)
- Polysulfide promotes neuroblastoma cell differentiation by accelerating calcium influx. (2015) (18)
- Hydrogen sulfide as a biological mediator. (2005) (18)
- The neurophysiology of hydrogen sulfide. (2011) (12)
- 3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S (2017) (11)
- A mechanism of retinal protection from light-induced degeneration by hydrogen sulfide (2012) (10)
- Hydrogen Sulfide and its Therapeutic Applications (2013) (9)
- H2S2014 in Kyoto: the 3rd International Conference on H2S in Biology and Medicine. (2015) (8)
- Pharmacological polysulfide suppresses glucose-stimulated insulin secretion in an ATP-sensitive potassium channel-dependent manner (2019) (7)
- 硫化水素：生合成，放出，生理機能 (2012) (6)
- Physiological roles of hydrogen sulfide and polysulfides. (2016) (6)
- Hydrogen sulfide signalling in the CNS ‐ Comparison with NO (2020) (6)
- Hydrogen Sulfide-Mediated Cellular Signaling and Cytoprotection (2013) (5)
- Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner. (2021) (5)
- [Hydrogen sulfide: production, release, and functions]. (2012) (5)
- Physiological function of hydrogen sulfide and beyond (2013) (4)
- Hydrogen sulfide signaling in the central nervous system -Comparison with nitric oxide. (2020) (4)
- P111: Inhibitor screening for 3-mercaptopyruvate sulfurtransferase (3MST) and cystathionine gamma lyase (CSE) (2014) (3)
- [Hydrogen sulfide as a physiological mediator: its function and therapeutic applications]. (2010) (3)
- Effect of metallothionein on granulocyte chemotaxis and superoxide generation. (1989) (3)
- 3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide that is stored as bound sulfane sulfur in the brain (2009) (2)
- A source of hydrogen sulfide and a mechanism of its release in the brain (2009) (2)
- A Case of Microvascular Angina Treated with Dai-kankyo-to (2003) (2)
- A Case of Respiratory Tract Infection Successfully Treated with Low-dose Daisaikotokabosho (2013) (2)
- Hydrogen Sulfide and the Regulation of Neuronal Activities (2004) (2)
- Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces H2S (2010) (2)
- Hydrogen Sulfide Is Severely Decreased in Alzheimer Disease Brains (2004) (2)
- PL-01 - Signaling molecules: hydrogen sulfide (H2S) and polysulfides (H2Sn) (2016) (2)
- Subjective Symptoms that can be indicators for Choosing Ogikeishigomotsuto (2005) (2)
- Three Cases of Fever Successfully Treated with Daijokito (2013) (2)
- Two Cases of Vomiting Successfully Treated with Daisaikoto (2011) (1)
- From neurotransmission to neuronal disorders (2021) (1)
- Hydrogen sulfide signaling in the central nervous system -Comparison with nitric oxide- (2020) (1)
- Endogenous reductants required for 3MST to produce H2S (2011) (1)
- S1-1 H2S and beyond (2014) (1)
- Physiological and Pathophysiological Functions of Hydrogen Sulfide (2012) (1)
- [Physiological functions of hydrogen sulfide (H2S) and its therapeutic applications]. (2013) (1)
- シグナル分子としての硫化水素（H2S），ポリサルファイド（H2Sn），亜硫酸（H2SO3） (2019) (1)
- Three Cases of Pneumonia Successfully Treated by Kampo Therapy (2006) (1)
- A Case of Painful Bedridden Patient with Multiple Fractures due to Osteoporosis Successfully Treated with Keishi-bushi-To (2005) (1)
- 2 Cases of Children Successfully Administered Kampo Formulae that Included Bushi or Uzu (2013) (1)
- Five Cases of Hymenoptera Stings and Centipede Bites Treated with Ourengedokuto and Inchingoreisan (2016) (1)
- Clinical Study on the Use of Seki-gan-ryo (2004) (1)
- Inactivation of Coliform Group by Pressure and Freezing Treatment (2004) (1)
- Four Patients with Calf Cramps who did not Respond to Shakuyakukanzoto but Responded well to Sokeikakketsuto (2011) (1)
- Combination therapy with tsumyakushigyakuto (tong-mai-si-ni-tang) and sekiganryo (chi-wan-liao) and the sequence of medication (2012) (1)
- The production and role of hydrogen sulfide and hydrogen polysulfides in mammalian cells (2021) (0)
- Contribution of polysulfides to the synergistic action of Hydrogen sulfide (H 2 S) and nitric oxide (NO) on TRPA1 (2018) (0)
- The production of hydrogen sulfide in glioblastoma cell lines (2022) (0)
- Laboratory animal science: Effects of polyphenols from seed shells of Japanese horse chestnut (Aesculus turbinate BLUME) on methotrexate-induced intestinal injury in rats (2011) (0)
- P79: Polysulfide exerts protective effect against cytotoxicity through Nrf2 signaling in neuronal cells (2014) (0)
- Production of hydrogen sulfide in mammalian cells (2020) (0)
- Signaling by hydrogen sulfide (H2S) and polysulfides (H2Sn) (2020) (0)
- Mechanisms of polysulfide production: enzymatic biosynthesis and chemical interaction between hydrogen sulfide and nitric oxide (2017) (0)
- Hydrogen Sulfide (H 2 S) and polysulfides (H 2 S n ) as signaling molecules (2018) (0)
- Synergistic action of hydrogen sulfide (H 2 S) and nitric oxide (NO) through generation of polysulfides (H 2 S n ) (2017) (0)
- Signaling molecules: H2S and H2Sn (2017) (0)
- 低レベル放射性廃棄物処分に対する濃度上限値評価コードGSA-GCL第2版の開発(受託研究) (2011) (0)
- A case of Megacolon Successfully Treated by Re-dosage of Kobokusanmotsuto; After an Attack of Pseudoaldosterenism induced by Chukenchuto (2006) (0)
- 硫化水素（H2S）とポリサルファイド（H2Sn）によるシグナル伝達 (2017) (0)
- 人間侵入に関する安全評価手法の開発,1; ボーリングシナリオを対象としたデータベースの整備(受託研究) (2010) (0)
- 397. TRU核種に関する野外核種移行試験,(V) (2003) (0)
- 「ひきがえる」蜻斜の正常発生過程に於ける表皮(感覚層)と網膜間に起こる水晶体誘発因に関する研究 (1980) (0)
- 4-6-1 小型機器用PEFCスタックの開発(4-6 燃料電池・改質1,Session 4 新エネルギー) (2012) (0)
- 高レベル放射性廃棄物地層処分の安全性の評価--地層処分システムの不確かさに対する確率論的解析手法の試適用(受託研究) (2009) (0)
- S9-5 Bound sulfur exerts protective effect against cytotoxicity in neuronal cells (2014) (0)
- 人間侵入に関する安全評価手法の開発,2; 放射性廃棄物処分における人間侵入シナリオ評価コードの開発(受託研究) (2010) (0)
- 地質・気候関連事象に関するFEPデータベースの整備; 隆起・沈降・地震活動・気候変動(受託研究) (2011) (0)
- IAEA SRS No. 44の評価手法に準拠したU-234, U-235及びU-238のクリアランスレベルの解析 (2010) (0)
- A Case of Inflammation of the Lips Successfully Treated with Otsujito (2013) (0)
- A Case Report of Recrudescent Cholangitis Successfully Treated with Kampo Medicine (2011) (0)
- The Meaning of \lceilFukuchukan\rfloor in the Abdominal Symptom of Daikenchuto-syo (2008) (0)
- [Signaling molecules hydrogen sulfide (H2S), polysulfides (H2Sn), and sulfite (H2SO3)]. (2019) (0)
- Hydrogen sulfide produced in mitochondria is involved in the protection of neurons from oxidative stress (2009) (0)
- A Case of Cyclic Neutropenia Satisfactorily Treated with Kampo Medicine (2004) (0)
- A Case of an Anorectic Post-gastrectomy Patient Treated with Kososan and Rikkunshito (2005) (0)
- Kampo Medicine Treatment of Acute Infection Be-treating Chronic Diseases (2010) (0)
- Usage of Ogonto to Address the High Prevalence of Vomiting and Diarrhea amongst Senior Citizens in Nursing Home (2011) (0)
- Kampo Therapies on an Isolated Island (2012) (0)
- P18 Application of fluorescence probe ’HSip-1’ to inhibitor screening for H2S producing enzyme (2012) (0)
- A Case of Ascites from Hepatocellular Carcinoma Treated with Boi-shomoku-teireki-daio-gan-ryo (2003) (0)
- Effectiveness of Syouhangekabukuryoto in Post Nasal Dripping (2011) (0)
- A Case of Cyclic Neutropenia Treated by Uzu-zai with Mengen, Unexpected Reaction (2010) (0)
- Kampo Therapy for Acute Viral Gastroenteritis (2009) (0)
- Flip Chip Attach Technology for Fine Pitch Connection by In Alloy Solder (1997) (0)
- Another pathway to produce hydrogen sulfide in the brain (2010) (0)
- Signaling molecules hydrogen sulfide (H2S), polysulfides (H2Sn) and sulfite (H2SO3) (2019) (0)
- Hydrogen trisulfide induced modulation of vascular tone in mice aorta (2018) (0)
- A Case of Subacute Thyroiditis Satisfactorily Treated with Kampo-therapy (2004) (0)
- Dihydrolipoic acid is a cofactor of 3-mercaptopyruvate sulfurtransferase for reducing 3-mercaptopyruvate to generate hydrogen sulfide (2010) (0)
- Regulation of hydrogen sulfide production and its cytoprotective effect in the retina (2011) (0)
- Another pathway to produce hydrogen sulfide in the brain (2011) (0)
- Hydrogen sulfide and polysulfides production form reaction intermediate of 3-mercaptopyruvate sulfurtransferase (2017) (0)
- The production of hydrogen sulfide and hydrogen polysulfides in mammalian cells (2017) (0)
- S9-4 Nociceptive action of hydrogen sulfide through the activation of transient receptor potential ankyrin 1 (TRPA1) (2014) (0)
- The sensitivity of differentiated astrocytes to hydrogen sulfide is diminished in the reactive astrocytes (2007) (0)
- Hydrogen Sulfide as a Synaptic Modulator (2005) (0)
- Signaling by hydrogen polysulfides (H2Sn) produced by the chemical interaction between hydrogen sulfide (H2S) and nitric oxide (NO) (2019) (0)
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What Schools Are Affiliated With Hideo Kimura?
Hideo Kimura is affiliated with the following schools:
