Hinrich Gronemeyer
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Computer Science
Hinrich Gronemeyer's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Hinrich Gronemeyer's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. (1990) (1536)
- A Unified Nomenclature System for the Nuclear Receptor Superfamily (1999) (1152)
- Principles for modulation of the nuclear receptor superfamily (2004) (1133)
- TIF2, a 160 kDa transcriptional mediator for the ligand‐dependent activation function AF‐2 of nuclear receptors. (1996) (1105)
- Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α (1995) (1036)
- A canonical structure for the ligand-binding domain of nuclear receptors (1996) (955)
- Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid (1995) (920)
- The nuclear receptor ligand-binding domain: structure and function. (1998) (853)
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
- The promise of retinoids to fight against cancer (2001) (752)
- The N‐terminal part of TIF1, a putative mediator of the ligand‐dependent activation function (AF‐2) of nuclear receptors, is fused to B‐raf in the oncogenic protein T18. (1995) (632)
- Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells (2005) (591)
- Senescence-associated reprogramming promotes cancer stemness (2017) (564)
- Steroid hormone receptors compete for factors that mediate their enhancer function (1989) (534)
- The coactivator TIF2 contains three nuclear receptor‐binding motifs and mediates transactivation through CBP binding‐dependent and ‐independent pathways (1998) (530)
- RAR and RXR modulation in cancer and metabolic disease (2007) (475)
- International Union of Pharmacology. LXIII. Retinoid X Receptors (2006) (472)
- Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications. (2000) (460)
- Differential ligand‐dependent interactions between the AF‐2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. (1996) (407)
- The N-terminal region of the chicken progesterone receptor specifies target gene activation (1988) (388)
- Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. (2000) (388)
- International Union of Pharmacology. LX. Retinoic Acid Receptors (2006) (375)
- Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain* (1999) (373)
- Transcription activation by estrogen and progesterone receptors. (1991) (364)
- Transcription factors 3: nuclear receptors. (1995) (355)
- Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL (2001) (349)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Cooperation of proto‐signals for nuclear accumulation of estrogen and progesterone receptors. (1992) (320)
- Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo. (1997) (320)
- Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor. (1990) (308)
- Co-regulator recruitment and the mechanism of retinoic acid receptor synergy (2002) (297)
- The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. (1989) (278)
- RAR‐specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage‐independent cell proliferation. (1995) (269)
- The Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP (2002) (263)
- The nuclear receptor factsbook (2002) (248)
- The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full‐length receptors to direct repeats. (1994) (247)
- Control of transcription activation by steroid hormone receptors (1992) (210)
- The patterns of binding of RAR, RXR and TR homo‐ and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains. (1993) (208)
- Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements. (1994) (206)
- Two distinct actions of retinoid-receptor ligands (1996) (205)
- Design of selective nuclear receptor modulators: RAR and RXR as a case study (2007) (200)
- The chicken progesterone receptor: sequence, expression and functional analysis. (1987) (200)
- Functions, therapeutic applications, and synthesis of retinoids and carotenoids. (2014) (200)
- Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. (1995) (196)
- Cell‐specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors. (1991) (190)
- Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors (1995) (172)
- Cloning of the chicken progesterone receptor. (1986) (166)
- Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers. (1997) (166)
- A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms. (1992) (164)
- Modulation of RXR function through ligand design. (2012) (160)
- Synergy between estrogen receptor α activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2 (2000) (159)
- Tumor suppressor IRF‐1 mediates retinoid and interferon anticancer signaling to death ligand TRAIL (2004) (147)
- Cross‐talk of vitamin D and glucocorticoids in hippocampal cells (2006) (141)
- Transient expression of human and chicken progesterone receptors does not support alternative translational initiation from a single mRNA as the mechanism generating two receptor isoforms. (1990) (140)
- A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor (2010) (135)
- Nuclear receptors in cell life and death (2001) (134)
- Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes (2009) (133)
- A mutation mimicking ligand‐induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers (1997) (132)
- Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function (2007) (129)
- A single amino acid that determines the sensitivity of progesterone receptors to RU486. (1992) (129)
- Conformational adaptation of agonists to the human nuclear receptor RARγ (1998) (128)
- The retinoic acid signaling pathway regulates anterior/posterior patterning in the nerve cord and pharynx of amphioxus, a chordate lacking neural crest. (2002) (127)
- Characterization of the Interaction between Retinoic Acid Receptor/Retinoid X Receptor (RAR/RXR) Heterodimers and Transcriptional Coactivators through Structural and Fluorescence Anisotropy Studies* (2005) (127)
- Single-tube linear DNA amplification (LinDA) for robust ChIP-seq (2011) (125)
- Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors (2006) (120)
- RAR‐independent RXR signaling induces t(15;17) leukemia cell maturation (1999) (117)
- Retinoids: potential in cancer prevention and therapy (2004) (114)
- Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor. (2005) (108)
- Towards novel paradigms for cancer therapy (2011) (108)
- The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer (2015) (108)
- Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation* (2011) (107)
- Mechanisms of antihormone action (1992) (104)
- Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists. (2009) (103)
- In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. (1996) (102)
- Localization of ecdysterone on polytene chromosomes of Drosophila melanogaster. (1980) (93)
- Recruitment of RXR by homotetrameric RARalpha fusion proteins is essential for transformation. (2007) (93)
- Retinoid X receptor alpha forms tetramers in solution. (1995) (93)
- DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells--toward a basis for the opposite actions elicited by two nuclear receptors? (2004) (89)
- Dissecting the retinoid-induced differentiation of F9 embryonal stem cells by integrative genomics (2011) (88)
- Rational design of RAR‐selective ligands revealed by RARβ crystal stucture (2004) (87)
- Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity. (2010) (86)
- Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. (1999) (86)
- A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors (2007) (83)
- Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor. (2007) (82)
- Retinoid X receptor-antagonistic diazepinylbenzoic acids. (1999) (81)
- Retinoid receptors and therapeutic applications of RAR/RXR modulators. (2012) (79)
- Therapeutic potential of selective modulators of nuclear receptor action. (1998) (79)
- How to finger DNA (1995) (77)
- Ligand- and DNA-induced dissociation of RXR tetramers. (1998) (75)
- Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors. (1993) (74)
- Progestin receptors: Isoforms and antihormone action (1991) (72)
- Cloning of the human glucocorticoid receptor cDNA. (1985) (69)
- Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin. (2011) (68)
- Expression of active hormone and DNA‐binding domains of the chicken progesterone receptor in E. coli. (1989) (63)
- Separation of Retinoid X Receptor Homo- and Heterodimerization Functions (2003) (62)
- HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation. (2010) (60)
- Pure and functionally homogeneous recombinant retinoid X receptor. (1994) (58)
- Homo- and heterodimers of the retinoid X receptor (RXR) activated transcription in yeast. (1994) (57)
- Aronia melanocarpa Juice Induces a Redox-Sensitive p73-Related Caspase 3-Dependent Apoptosis in Human Leukemia Cells (2012) (56)
- Molecular mechanisms of retinoid action. (2001) (55)
- Immunological similarity between the chick oviduct progesterone receptor forms A and B. (1985) (54)
- Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs (2006) (53)
- Retinoic-acid-induced apoptosis in leukemia cells. (2004) (53)
- Nuclear receptor superfamily: Principles of signaling (2003) (51)
- In vitro activity of the transcription activation functions of the progesterone receptor. Evidence for intermediary factors. (1992) (50)
- Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells. (2001) (50)
- HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway. (2007) (50)
- Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity. (1998) (50)
- Characterization of multiple mRNAs originating from the chicken progesterone receptor gene. Evidence for a specific transcript encoding form A. (1990) (50)
- Acute myeloid leukemia: therapeutic impact of epigenetic drugs. (2005) (49)
- Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerization (1993) (47)
- Death Receptor Pathway Activation and Increase of ROS Production by the Triple Epigenetic Inhibitor UVI5008 (2011) (47)
- Retinoid receptor subtype-selective modulators through synthetic modifications of RARgamma agonists. (2009) (45)
- Role of ligand in retinoid signaling. 9-cis-retinoic acid modulates the oligomeric state of the retinoid X receptor. (1995) (45)
- Epigenetic profiling of the antitumor natural product psammaplin A and its analogues. (2011) (45)
- Synthesis, Crystal Structure Analysis, and Pharmacological Characterization of Disila-bexarotene, a Disila-Analogue of the RXR-Selective Retinoid Agonist Bexarotene (2005) (45)
- Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM (2006) (44)
- Indole-derived psammaplin A analogues as epigenetic modulators with multiple inhibitory activities. (2012) (43)
- A quality control system for profiles obtained by ChIP sequencing (2013) (43)
- Allosteric Effects Govern Nuclear Receptor Action: DNA Appears as a Player (2009) (41)
- Evidence for two structurally related progesterone receptors in chick oviduct cytosol (1983) (40)
- The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation (2016) (39)
- Human cells contain natural double-stranded RNAs with potential regulatory functions (2014) (39)
- PIAS3 (protein inhibitor of activated STAT‐3) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF2 (2002) (39)
- Ligand-dependent interaction of nuclear receptors with potential transcriptional intermediary factors (mediators). (1996) (38)
- Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor. (1992) (37)
- Affinity labelling of steroid hormone receptors (1986) (37)
- Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy-3-(3-alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers. (2009) (37)
- Purification, functional characterization, and crystallization of the ligand binding domain of the retinoid X receptor. (1995) (36)
- Single-tube linear DNA amplification for genome-wide studies using a few thousand cells (2012) (36)
- Action mechanism of retinoid-synergistic dibenzodiazepines. (1997) (36)
- Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology (2009) (36)
- Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: purification, crystallization, and preliminary X-ray diffraction analysis. (2000) (35)
- Characterization of the rat liver glucocorticoid receptor purified by DNA-cellulose and ligand affinity chromatography. (1984) (35)
- Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia (2014) (34)
- CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity (2018) (32)
- The DNA Binding Pattern of the Retinoid X Receptor Is Regulated by Ligand-dependent Modulation of Its Oligomeric State* (1997) (32)
- Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells (2017) (32)
- Silicon Analogues of the Retinoid Agonists TTNPB and 3‐Methyl‐TTNPB, Disila‐TTNPB and Disila‐3‐methyl‐TTNPB: Chemistry and Biology (2007) (30)
- Growth factor-antagonized rexinoid apoptosis involves permissive PPARgamma/RXR heterodimers to activate the intrinsic death pathway by NO. (2009) (29)
- Retinoic acid receptor modulators: a perspective on recent advances and promises (2011) (29)
- Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation. (2012) (29)
- Mutation of isoleucine 747 by a threonine alters the ligand responsiveness of the human glucocorticoid receptor. (1996) (27)
- Control of transcription of the chicken progesterone receptor gene. In vitro and in vivo studies. (1991) (27)
- Retinoic acid determines life span of leukemic cells by inducing antagonistic apoptosis-regulatory programs. (2005) (27)
- Leukemia: beneficial actions of retinoids and rexinoids. (2004) (27)
- TIF2 Mediates the Synergy between RARα1 Activation Functions AF-1 and AF-2* (2002) (25)
- Transcription activation by nuclear receptors. (1993) (25)
- Quality indicators increase the reliability of microarray data. (2002) (24)
- Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}. (2010) (24)
- Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms (2010) (24)
- Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry. (2004) (23)
- C3 Halogen and C8′′ Substituents on Stilbene Arotinoids Modulate Retinoic Acid Receptor Subtype Function (2009) (23)
- Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells (2014) (23)
- Characterising ChIP-seq binding patterns by model-based peak shape deconvolution (2013) (21)
- Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities. (1997) (21)
- Synthesis and Pharmacological Characterization of Disila‐AM80 (Disila‐tamibarotene) and Disila‐AM580, Silicon Analogues of the RARα‐Selective Retinoid Agonists AM80 (Tamibarotene) and AM580 (2009) (20)
- Retinoic Acid Analogues Inhibit Human Herpesvirus 8 Replication (2008) (20)
- Retinoids and TRAIL: two cooperating actors to fight against cancer. (2004) (20)
- Insights into the mechanism of the site-selective sequential palladium-catalyzed cross-coupling reactions of dibromothiophenes/dibromothiazoles and arylboronic acids. Synthesis of PPARβ/δ agonists (2006) (20)
- Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis (2016) (20)
- Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family (2000) (19)
- Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge. (2010) (19)
- Inverse agonists and antagonists of retinoid receptors. (2010) (19)
- Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis (2016) (19)
- Genome-wide studies of nuclear receptors in cell fate decisions. (2013) (18)
- Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis (2014) (17)
- Nuclear receptors. How to finger DNA. (1995) (16)
- A new era of cancer therapy: cancer cell targeted therapies are coming of age. (2008) (16)
- CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity (2020) (15)
- TRAIL: At the Center of Drugable Anti-Tumor Pathways (2005) (15)
- Purification of the Human RARγ Ligand-Binding Domain and Crystallization of Its Complex with All-transRetinoic Acid (1997) (15)
- Modeling gene-regulatory networks to describe cell fate transitions and predict master regulators (2018) (15)
- Pyrazine Arotinoids with Inverse Agonist Activities on the Retinoid and Rexinoid Receptors (2009) (14)
- NGS-QC Generator: A Quality Control System for ChIP-Seq and Related Deep Sequencing-Generated Datasets (2016) (14)
- Highly Potent Naphthofuran‐Based Retinoic Acid Receptor Agonists (2009) (14)
- Affinity labelling and cloning of steroid and thyroid hormone receptors (1988) (14)
- Photoaffinity labelling of steroid hormone binding sites (1985) (14)
- Transformation-Dependent Silencing of Tumor-Selective Apoptosis-Inducing TRAIL by DNA Hypermethylation Is Antagonized by Decitabine (2011) (14)
- Retinoic acid-response elements with a highly repetitive structure isolated by immuno-selection from genomic DNA (1993) (14)
- Retinoic acid via RARalpha inhibits the expression of 24-hydroxylase in human prostate stromal cells. (2005) (13)
- An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist (2015) (12)
- New retinoid chemotypes: 9-cis-retinoic acid analogs with hydrophobic rings derived from terpenes as selective RAR agonists. (2008) (12)
- Decryption of the Retinoid Death Code in Leukemia (2002) (12)
- Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis (2011) (12)
- Characterization and purification of human retinoic acid receptor-gamma 1 overexpressed in the baculovirus-insect cell system. (1992) (12)
- Thioether Analogues of Disulfide‐Bridged Cyclic Peptides Targeting Death Receptor 5: Conformational Analysis, Dimerisation and Consequences for Receptor Activation (2015) (12)
- TIF2 mediates the synergy between RARalpha 1 activation functions AF-1 and AF-2. (2002) (11)
- Erratum: A canonical structure for the ligand-binding domain of nuclear receptors (1996) (11)
- Rexinoid-triggered differentiation and tumor-selective apoptosis of AML by protein kinase A-mediated de-subordination of RXR (2006) (11)
- Total synthesis of the proposed structures of the DNA methyl transferase inhibitors peyssonenynes, and structural revision of peyssonenyne B. (2011) (10)
- Sequential chromatin immunoprecipitation protocol for global analysis through massive parallel sequencing (reChIP-seq) (2012) (10)
- 9-cis-retinoic acid analogues with bulky hydrophobic rings: new RXR-selective agonists. (2004) (10)
- POLYPHEMUS: R package for comparative analysis of RNA polymerase II ChIP-seq profiles by non-linear normalization (2011) (10)
- Twenty years of nuclear receptors (2006) (9)
- RAR-RXR selectivity and biological activity of new retinoic acid analogues with heterocyclic or polycyclic aromatic systems. (2002) (9)
- The coactivator TIF 2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and-independent pathways (2013) (8)
- Epigenetic multiple modulators. (2011) (8)
- Photoinduced bonding of endogenous ecdysterone to salivary gland chromosomes of Chironomus tentans (2004) (7)
- The 12th international conference on differentiation therapy: targeting the aberrant growth, differentiation and cell death programs of cancer cells (2011) (7)
- A reappraisal of ecdysteroid binding in drosophila (1983) (7)
- Retinoid Receptor‐Selective Modulators (2015) (7)
- Versatile copurification procedure for rapid isolation of homogeneous RAR-RXR heterodimers. (1999) (6)
- Faculty Opinions recommendation of Noncoding deletions reveal a gene that is critical for intestinal function. (2019) (6)
- Complexity against current cancer research: Are we on the wrong track? (2021) (6)
- TARDIS, a targeted RNA directional sequencing method for rare RNA discovery (2015) (5)
- Assessing quality standards for ChIP-seq and related massive parallel sequencing-generated datasets: When rating goes beyond avoiding the crisis (2014) (5)
- Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity (2022) (5)
- Design and Stereoselective Synthesis of Retinoids with Ferrocene or N‐Butylcarbazole Pharmacophores that Induce Post‐Differentiation Apoptosis in Acute Promyelocytic Leukemia Cells (2011) (5)
- A comprehensive resource for retrieving, visualizing, and integrating functional genomics data (2019) (5)
- Fingering modulators of retinoic acid signaling identifies new prognostic marker for neuroblastoma. (2009) (5)
- Molecular Basis of Sex Hormone Receptor Function (1998) (5)
- Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification. (2016) (5)
- [Nuclear receptors. Hormones, anti-hormones and regulation of the transcription]. (1991) (5)
- transcripts encoding thetwo functionally different humanprogesterone receptorformsA andB (1990) (5)
- PIAS 3 ( protein inhibitor of activated STAT3 ) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF 2 (2002) (5)
- Peptide sequencing of the chick oviduct progesterone receptor form B (1987) (5)
- Surface-enhanced Raman scattering and fluorescence spectroscopy reveal molecular interactions of all-trans retinoic acid and RARγ ligand-binding domain (1998) (5)
- Gene regulatory network reconstruction incorporating 3D chromosomal architecture reveals key transcription factors and DNA elements driving neural lineage commitment (2019) (4)
- Preclinical Development Death Receptor Pathway Activation and Increase of ROS Production by the Triple Epigenetic Inhibitor UVI 5008 (2011) (4)
- Dual RXR Agonists and RAR Antagonists Based on the Stilbene Retinoid Scaffold. (2014) (4)
- A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures (2012) (4)
- Suppression of tumorigenicity in T-cell lymphoma hybrids is correlated with changes in myc expression and DNA replication of the myc chromosomal domain (2004) (3)
- Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention (2019) (3)
- 9206 POSTER Redox-sensitive P73-related Pro-apoptotic Effect of the Polyphenolic-rich Aronia Melanocarpa Juice on Human Acute Lymphoblastic Leukemia Cells (2011) (3)
- Rexinoid therapy bypasses the differentiation block associated with acute promyelocytic leukemia harboring the PLZF/RAR alpha rearrangement. (2001) (3)
- Highly dynamic chromatin interactions drive neurogenesis through gene regulatory networks (2018) (3)
- Nuclear receptor coactivators as potential therapeutical targets: the HATs on the mouse trap (1999) (3)
- 3 – Ligand binding (2002) (3)
- Integrative genomics to dissect retinoid functions. (2014) (3)
- LOGIQA: a database dedicated to long-range genome interactions quality assessment (2016) (3)
- Epimetheus - a multi-profile normalizer for epigenomic sequencing data (2017) (3)
- Structure-activity relationships of methylene or terminal side chain modified retinoids on the differentiation and cell death signaling in NB4 promyelocytic leukemia cells. (2004) (3)
- Development of biotin-retinoid conjugates as chemical probes for analysis of retinoid function. (2018) (3)
- Modulation of Retinoic Acid Receptor Subtypes by 5‐ and 8‐Substituted (Naphthalen‐2‐yl)‐based Arotinoids (2015) (2)
- Synthesis of a radiolabelled retinoid X receptor (RXR) specific ligand (1997) (2)
- Inference from RNA interference: Suggestions to our authors (2019) (2)
- Structure of the ligand binding domain of the Retinoic Acid Receptor beta (2004) (2)
- Topic 1 . 1 Nuclear receptor superfamily : Principles of signaling * (2003) (2)
- Retinobenzoic Acids. Part 8. Regulation of Retinoidal Actions by Diazepinylbenzoic Acids. Retinoid Synergists Which Activate the RXR—RAR Heterodimers. (1998) (2)
- Big Data: The good, the bad and the ugly (2021) (2)
- Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification (2016) (2)
- [Retinoic acid has an antiestrogenic effect on different regulated estrogen genes in different cellular types]. (1991) (2)
- RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis. (2004) (1)
- CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity (2018) (1)
- Receptor mechanisms: principles of agonism. 23-25 July 1998, Merano, Italy. (1998) (1)
- 4 – Molecular mechanisms of transcriptional regulation (2002) (1)
- Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC‐MEF2 complexes (2020) (1)
- 1 – General organization of nuclear receptors (2002) (1)
- Promising strategies: Combination of epigenetic inhibitors for cancer therapy (2020) (1)
- 9‐cis‐Retinoic Acid Analogues with Bulky Hydrophobic Rings: New RXR‐Selective Agonists. (2005) (1)
- Insights into the mechanism of the site-selective sequential palladium-catalyzed cross-coupling reactions of dibromothiophenes/dibromothiazoles and arylboronic acids. Synthesis of PPARbeta/delta agonists. (2006) (1)
- Nuclear Receptors as Targets for Drug Design: New Options and Old Challenges (1998) (1)
- 2 – DNA recognition by nuclear receptors (2002) (1)
- Modeling gene-regulatory networks to describe cell fate transitions and predict master regulators (2018) (1)
- Introduction to THE NUCLEAR RECEPTORS (2002) (1)
- Surface-enhanced Raman scattering and fluorescence spectroscopy reveal molecular interactions of all-trans retinoic acid and RAR gamma ligand-binding domain. (1998) (1)
- RARβ ligand‐binding domain bound to an SRC‐1 co‐activator peptide: purification, crystallization and preliminary X‐ray diffraction analysis (2004) (1)
- Synthesis of the PPARbeta/delta-selective agonist GW501516 and C4-thiazole-substituted analogs. (2006) (1)
- Faculty Opinions recommendation of Widespread and functional RNA circularization in localized prostate cancer. (2019) (1)
- Enantioselective apoptosis induction in histiocytic lymphoma cells and acute promyelocytic leukemia cells (2013) (1)
- Syddansk Universitet The KDM 5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation (2017) (1)
- Functional Domains of Steroid Hormone Receptors (1989) (1)
- Signal Transduction and Structure of Nuclear Receptors (2002) (1)
- Characterising ChIP-seq binding patterns by model-based peak shape deconvolution (2013) (1)
- Reductionism that leads to manuscript rejection (2021) (0)
- Faculty Opinions recommendation of Three-dimensional intact-tissue sequencing of single-cell transcriptional states. (2019) (0)
- Faculty Opinions recommendation of Molecular architecture of lineage allocation and tissue organization in early mouse embryo. (2019) (0)
- Enantioselective apoptosis induction in histiocytic lymphoma cells and acute promyelocytic leukemia cells (2012) (0)
- Faculty Opinions recommendation of Contact area-dependent cell communication and the morphological invariance of ascidian embryogenesis. (2020) (0)
- Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid. (1997) (0)
- Faculty Opinions recommendation of RNA proximity sequencing reveals the spatial organization of the transcriptome in the nucleus. (2019) (0)
- Retinoid and rexinoid induced apoptosis in leukaemia:towards novel option for therapy (2003) (0)
- Epimetheus - a multi-profile normalizer for epigenomic sequencing data (2017) (0)
- 90 Regulation of cell life and death by retinoids (2003) (0)
- Mechanism of nuclear receptor action: Structure and function (1999) (0)
- TP53 Mutations Negatively Impact Survival of Acute Myeloid Leukemia Patients Treated with Standard Doses of Azacitidine (2018) (0)
- Functional Analysis of the Estrogen and Progesterone Receptors (1988) (0)
- Structure and function of nuclear receptors--EMBO workshop. 25-27 May 1999, Villefranche-sur-Mer, Nice, France. (1999) (0)
- Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator (2004) (0)
- Modified glucocorticoid receptor, fusion proteins and dna and this receptor and fusion proteins coding (1997) (0)
- Synergistic activation of RARb and RARg nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARa-controlled programs (2022) (0)
- Faculty Opinions recommendation of Spatially confined sub-tumor microenvironments in pancreatic cancer. (2021) (0)
- The retinoic acid receptor system: From the mechanisms of action to the regulation of cell life and death (2004) (0)
- DAX1 and SHP (2002) (0)
- Post-maturation apoptosis of retinoid-insensitive myeloid blast cells by rexinoid-PKA crosstalk. (2002) (0)
- Facteur-2 intermediaire de la transcription (1997) (0)
- Leukemic transformation by the APL fusion protein PRKAR1A-RAR (cid:1) critically depends on recruitment of RXR (cid:1) (2010) (0)
- Molecular Basis of Sex Hormone Receptor Function: New Targets for Intervention (2013) (0)
- The comprehensive roadmaps of reprogramming and transformation unveiled antagonistic roles for bHLH transcription factors in the control of cellular plasticity (2020) (0)
- Nuclear glucocorticoid receptor alters, DNA fragments coding for said receiver and processes in which they are implemented (1996) (0)
- Coregulators of the activation function AF-2 of nuclear receptors Structure-function analysis (1999) (0)
- 266 UVI5008, a novel epigenetic enzyme inhibitor (2010) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Faculty Opinions recommendation of Decoding gene regulation in the fly brain. (2022) (0)
- DHR96 and DAF-12 (2002) (0)
- Steroids, Retinoids, and their Mode of Action (1992) (0)
- 8 – Deregulation in disease and novel therapeutic targets (2002) (0)
- Combined Knock Down of Histone Demethylases Jarid1A and Jarid1B Inhibits Adipogenesis (2011) (0)
- TR2 and TR4 (2002) (0)
- Evaluation Panel: HEALTH SCIENCES-Biomedicine and Molecular Biology (2019) (0)
- 9 – Genes and evolution (2002) (0)
- SF-1 and FTZ-F1 (2002) (0)
- LOGIQA: a database dedicated to long-range genome interactions quality assessment (2016) (0)
- FUNCTIONAL ANALYSIS OF THE ESTROGEN AND (1988) (0)
- 6 – Antagonist action (2002) (0)
- Synthesis of the PPARβ/δ-Selective Agonist GW501516 and C4-Thiazole-Substituted Analogues. (2006) (0)
- The MeDiChISeq ChIP-seq deconvolution package (2013) (0)
- 5 – RXR subordination in heterodimers (2002) (0)
- Selectivity and promiscuity of target enhancers for distinct classes of nuclear receptors (1994) (0)
- Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis (2016) (0)
- Induction of Tumor-Selective Cytotoxicity by Myrtus communis L. Extract and its Bioactive Metabolite 1, 8-cineole (2021) (0)
- Chapter 24:Retinoic Acid Receptors and their Modulators: Structural and Functional Insights (2012) (0)
- Japanese Society for Retinoid Research--tenth symposium. 17-19 November 1999, Tokyo, Japan. (2000) (0)
- Faculty Opinions recommendation of Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. (2022) (0)
- Inside Cover: Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology (ChemMedChem 7/2009) (2009) (0)
- Modelling temporal transcriptional regulatory programs activation over reconstructed gene regulatory networks describing cell fate transitions (2016) (0)
- French academic strenghts in epigenetic and cancer (2016) (0)
- Transcription factor-2 between TIF2 (1997) (0)
- Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs (2022) (0)
- Human cells contain double-stranded RNAs with key regulatory potential. (2014) (0)
- Recruitment of RXRα by Homo-Oligomeric RARα Is a Key for RARα-Mediated Transformation. (2006) (0)
- Cover Picture: A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures (ChemMedChem 12/2012) (2012) (0)
- 7 – Nuclear receptors: platforms for multiple signal integration (2002) (0)
- Exome Sequencing Identifies Mecom Missense Variant As Prognostic Marker for Overall Survival of Elderly Acute Myeloid Patients Treated with Azacitidine (2018) (0)
- About the variability, quality and reproducibility of ChIP-seq data (2016) (0)
- Issue Information (2019) (0)
- Issue Information (2019) (0)
- Contents Vol. 96, 2019 (2019) (0)
- Issue Information (2019) (0)
- Issue Information (2019) (0)
- Contents Vol. 97, 2019 (2019) (0)
- Issue Information (2019) (0)
- Issue Information (2020) (0)
- Front & Back Matter (2012) (0)
- Issue Information (2020) (0)
- Issue Information (2019) (0)
- Mechanism of action and cancer therapeutic potential of retinoids. (2006) (0)
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What Schools Are Affiliated With Hinrich Gronemeyer?
Hinrich Gronemeyer is affiliated with the following schools:
