Hirofumi Hamada
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Hirofumi Hamada's AcademicInfluence.com Rankings
Hirofumi Hamadaphilosophy Degrees
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#7625
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#10866
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Logic
#4671
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#5990
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Hirofumi Hamadabiology Degrees
Biology
#10305
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#13622
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Immunology
#642
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#663
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Philosophy Biology
Hirofumi Hamada's Degrees
- PhD Immunology University of Tokyo
- Doctorate Medicine University of Tokyo
Why Is Hirofumi Hamada Influential?
(Suggest an Edit or Addition)Hirofumi Hamada's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. (1993) (2825)
- Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. (1987) (2758)
- p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload (2007) (848)
- Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion. (2005) (632)
- Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein. (1989) (611)
- Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model (2004) (587)
- Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. (1986) (561)
- Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16. (1988) (478)
- Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model. (2005) (400)
- BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model. (2004) (336)
- Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase. (1988) (304)
- Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy (2006) (273)
- Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia. (2006) (271)
- Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. (1986) (258)
- BDNF-Hypersecreting Human Mesenchymal Stem Cells Promote Functional Recovery, Axonal Sprouting, and Protection of Corticospinal Neurons after Spinal Cord Injury (2009) (255)
- Proteasome Inhibitors Induce Cytochrome c–Caspase-3-Like Protease-Mediated Apoptosis in Cultured Cortical Neurons (2000) (243)
- Therapeutic Benefits by Human Mesenchymal Stem Cells (hMSCs) and Ang-1 Gene-Modified hMSCs after Cerebral Ischemia (2008) (236)
- Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy (2005) (219)
- Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters. (1987) (215)
- Intravenous administration of glial cell line‐derived neurotrophic factor gene‐modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat (2006) (208)
- Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome (2010) (206)
- Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease (2004) (203)
- A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload. (2001) (194)
- In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene. (1997) (192)
- Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo. (2004) (181)
- Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells. (1988) (181)
- High Level Calcineurin Activity Predisposes Neuronal Cells to Apoptosis* (1999) (169)
- Immunocytochemical localization of P170 at the plasma membrane of multidrug-resistant human cells. (1987) (152)
- A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells. (1987) (145)
- Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells. (2012) (139)
- Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT)-transfected human stromal cells. (2003) (138)
- Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia (2009) (137)
- ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells. (1988) (130)
- Gene therapy for α‐fetoprotein‐producing human hepatoma cells by adenovirus‐mediated transfer of the herpes simplex virus thymidine kinase gene (1996) (125)
- Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. (1998) (120)
- Neurorescue effects of VEGF on a rat model of Parkinson's disease (2005) (116)
- Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro. (1996) (115)
- An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives (2008) (114)
- Intensified antitumor immunity by a cancer vaccine that produces granulocyte-macrophage colony-stimulating factor plus interleukin 4. (1996) (113)
- Generation of fiber-mutant recombinant adenoviruses for gene therapy of malignant glioma. (1998) (112)
- Ex Vivo Large‐Scale Generation of Human Platelets from Cord Blood CD34+ Cells (2006) (110)
- Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. (1996) (110)
- Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber (2003) (109)
- Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil. (1998) (108)
- Expression level of Bcl-2 determines anti- or proapoptotic function. (1999) (107)
- Highly augmented cytopathic effect of a fiber-mutant E1B-defective adenovirus for gene therapy of gliomas. (1999) (105)
- Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages (2008) (105)
- Mesenchymal stem cells derived from peripheral blood protects against ischemia. (2007) (104)
- Efficient BMP2 gene transfer and bone formation of mesenchymal stem cells by a fiber-mutant adenoviral vector. (2003) (103)
- Adenovirus-mediated inducible gene expression through tetracycline-controllable transactivator with nuclear localization signal. (1997) (102)
- Telomerized human multipotent mesenchymal cells can differentiate into hematopoietic and cobblestone area-supporting cells. (2003) (102)
- Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism (2007) (97)
- Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies (1989) (97)
- Adenovirus-mediated transfer of p33ING1 with p53 drastically augments apoptosis in gliomas. (1999) (90)
- Specialized Localization of P‐Glycoprotein Recognized by MRK 16 Monoclonal Antibody in Endothelial Cells of the Brain and the Spinal Cord (1990) (90)
- Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. (2004) (90)
- In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma. (1997) (87)
- Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. (1998) (85)
- Detection of multidrug resistance markers, P-glycoprotein and mdr1 mRNA, in human leukemia cells. (1987) (80)
- Tumor-specific gene expression in carcinoembryonic antigen--producing gastric cancer cells using adenovirus vectors. (1996) (80)
- Gene Therapy for Pancreatic Cancer Using an Adenovirus Vector Encoding Soluble flt-1 Vascular Endothelial Growth Factor Receptor (2002) (79)
- Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia (2010) (78)
- Adenoviral-delivered angiopoietin-1 reduces the infarction and attenuates the progression of cardiac dysfunction in the rat model of acute myocardial infarction. (2003) (76)
- Experimental gene therapy for brain tumors using adenovirus-mediated transfer of cytosine deaminase gene and uracil phosphoribosyltransferase gene with 5-fluorocytosine. (2000) (75)
- Adoptive immunotherapy with murine tumor-specific T lymphocytes engineered to secrete interleukin 2. (1994) (74)
- The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model (2005) (73)
- Overexpression of CD82 on human T cells enhances LFA‐1 / ICAM‐1‐mediated cell‐cell adhesion: functional association between CD82 and LFA‐1 in T cell activation (1999) (73)
- Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax (1999) (72)
- In vivo efficacy and toxicity of 5-fluorocytosine/cytosine deaminase gene therapy for malignant gliomas mediated by adenovirus (2000) (72)
- Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice. (1998) (71)
- Enhanced therapeutic efficacy of tumor RNA-pulsed dendritic cells after genetic modification with lymphotactin. (1999) (69)
- Apparent stronger expression in the human adrenal cortex than in the human adrenal medulla of Mr 170,000-180,000 P-glycoprotein. (1988) (67)
- Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury (1999) (66)
- Enhanced antitumor effect of RGD fiber-modified adenovirus for gene therapy of oral cancer (2003) (66)
- Local tumor irradiation augments the antitumor effect of cytokine-producing autologous cancer cell vaccines in a murine glioma model (2002) (64)
- Human corneal endothelial cells expressing programmed death-ligand 1 (PD-L1) suppress PD-1+ T helper 1 cells by a contact-dependent mechanism. (2009) (63)
- E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor. (2002) (62)
- Therapeutic effect of suicide gene-transferred mesenchymal stem cells in a rat model of glioma (2012) (62)
- Purification of the Mr 22,000 calcium-binding protein (sorcin) associated with multidrug resistance and its detection with monoclonal antibodies. (1988) (62)
- Differential regulation of Fas-mediated apoptosis of rheumatoid synoviocytes by tumor necrosis factor alpha and basic fibroblast growth factor is associated with the expression of apoptosis-related molecules. (2000) (62)
- Pre‐administration of angiopoietin‐1 followed by VEGF induces functional and mature vascular formation in a rabbit ischemic model (2003) (62)
- Adult neural stem and progenitor cells modified to secrete GDNF can protect, migrate and integrate after intracerebral transplantation in rats with transient forebrain ischemia (2007) (61)
- Periostin and bone marrow fibrosis (2008) (61)
- Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus. (2000) (60)
- Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta2m-/- repopulating cells. (2004) (59)
- Transduction of Soluble Flt-1 Gene to Peritoneal Mesothelial Cells Can Effectively Suppress Peritoneal Metastasis of Gastric Cancer (2004) (58)
- Human beta-defensin-2 induction in Helicobacter pylori-infected gastric mucosal tissues: antimicrobial effect of overexpression. (2003) (57)
- Bcl-xL gene transfer protects the heart against ischemia/reperfusion injury. (2003) (57)
- Novel gene therapy for rheumatoid arthritis by FADD gene transfer: induction of apoptosis of rheumatoid synoviocytes but not chondrocytes (2000) (56)
- In vivo transfer of hepatocyte growth factor gene accelerates proliferation of hepatic oval cells in a 2‐acetylaminofluorene/partial hepatectomy model in rats (2000) (55)
- Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia. (2005) (54)
- Therapeutic time window of mesenchymal stem cells derived from bone marrow after cerebral ischemia (2010) (54)
- Adenovirus-mediated delivery of the PTEN gene inhibits cell growth by induction of apoptosis in endometrial cancer. (1999) (53)
- Successful adoptive immunotherapy of murine poorly immunogenic tumor with specific effector cells generated from gene-modified tumor-primed lymph node cells. (1999) (52)
- Adenovirus-mediated ex vivo gene transfer of basic fibroblast growth factor promotes collateral development in a rabbit model of hind limb ischemia (2001) (50)
- Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors. (2002) (49)
- Carcinoembryonic Antigen–Targeted Selective Gene Therapy for Gastric Cancer through FZ33 Fiber-Modified Adenovirus Vectors (2006) (47)
- Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber‐mutant adenoviral BMP2 gene (2005) (47)
- Facilitation of adenoviral wild-type p53-induced apoptotic cell death by overexpression of p33ING1 in T.Tn human esophageal carcinoma cells (2002) (47)
- E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. (2003) (46)
- Enhancement of voltage-gated Na+ channel current associated with multidrug resistance in human leukemia cells. (1987) (46)
- Adenovirus mediated p53 tumour suppressor gene therapy for human gastric cancer cells in vitro and in vivo (1999) (45)
- Adenovirus-mediated transfer of Bax with caspase-8 controlled by myelin basic protein promoter exerts an enhanced cytotoxic effect in gliomas (2000) (44)
- Adeno-retroviral chimeric viruses as in vivo transducing agents (1999) (44)
- Functional analysis of CD82 in the early phase of T cell activation: roles in cell adhesion and signal transduction (1998) (43)
- Adenovirus-mediated transfer of caspase-8 augments cell death in gliomas: implication for gene therapy. (2000) (43)
- Target gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by E1B55k-attenuated adenovirus. (2001) (43)
- Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of Escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine (2000) (41)
- Adenovirus-mediated gene therapy of gastric carcinoma using cancer-specific gene expression in vivo. (1997) (41)
- Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. (2000) (41)
- Generation of reactive oxygen species and activation of NF‐κB by non‐Aβ component of Alzheimer's disease amyloid (2002) (40)
- Bcl-xL Gene Transfer Inhibits Bax Translocation and Prolongs Cardiac Cold Preservation Time in Rats (2005) (39)
- Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression. (2000) (39)
- Enhanced brain angiogenesis in chronic cerebral hypoperfusion after administration of plasmid human vascular endothelial growth factor in combination with indirect vasoreconstructive surgery. (2005) (38)
- Vaccine effect of granulocyte–macrophage colony-stimulating factor or CD80 gene-transduced murine hematopoietic tumor cells and their cooperative enhancement of antitumor immunity (1998) (37)
- Mouse-human chimeric antibody against the multidrug transporter P-glycoprotein. (1990) (36)
- VSV-G-pseudotyped retroviral packaging through adenovirus-mediated inducible gene expression. (1997) (36)
- Adenovirus-mediated transfer of p53 and Fas ligand drastically enhances apoptosis in gliomas (2000) (36)
- Monoclonal Anti‐P‐glycoprotein Antibody‐dependent Killing of Multidrug‐resistant Tumor Cells by Human Mononuclear Cells (1990) (35)
- Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration. (2005) (35)
- Metalloprotease inhibitors block release of soluble CD27 and enhance the immune stimulatory activity of chronic lymphocytic leukemia cells. (2007) (34)
- Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells. (1997) (34)
- In vivo Adenovirus‐mediated Prodrug Gene Therapy for Carcinoembryonic Antigen‐producing Pancreatic Cancer (1998) (33)
- Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas (2000) (33)
- Superiority of interleukin-12-transduced murine lung cancer cells to GM-CSF or B7-1 (CD80) transfectants for therapeutic antitumor immunity in syngeneic immunocompetent mice. (1998) (33)
- Induction of potent antitumor response by vaccination with tumor lysate-pulsed macrophages engineered to secrete macrophage colony-stimulating factor and interferon-γ (2000) (33)
- Transplantation of sendai viral angiopoietin-1-modified mesenchymal stem cells for ischemic limb disease (2010) (32)
- Datopotamab Deruxtecan, a Novel TROP2-directed Antibody–drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells (2021) (32)
- Mr 85,000 membrane protein specifically expressed in adriamycin-resistant human tumor cells. (1988) (32)
- Efficient Retrovirus‐mediated Cytokine‐gene Transduction of Primary‐cultured Human Glioma Cells for Tumor Vaccination Therapy (1997) (32)
- Effect of Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells on Mice Infected with Prions (2009) (31)
- Adenovirus-mediated GM-CSF gene and cytosine deaminase gene transfer followed by 5-fluorocytosine administration elicit more potent antitumor response in tumor-bearing mice (1998) (31)
- Lymphotactin cotransfection enhances the therapeutic efficacy of dendritic cells genetically modified with melanoma antigen gp100 (2002) (30)
- Involvement of the SKP2–p27KIP1 pathway in suppression of cancer cell proliferation by RECK (2012) (30)
- Apoptosis Induction With 5-Fluorocytosine/Cytosine Deaminase gene Therapy for Human Malignant Glioma Cells Mediated by Adenovirus (2004) (30)
- Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells. (2006) (30)
- Modulation of Motility and Proliferation of Glioma Cells by Hepatocyte Growth Factor (1997) (30)
- Gene therapy using an adenovirus vector for apoptosis-related genes is a highly effective therapeutic modality for killing glioma cells. (2003) (29)
- Development of an oncolytic HSV vector fully retargeted specifically to cellular EpCAM for virus entry and cell-to-cell spread (2016) (29)
- Adenoviral-mediated transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil. (2000) (29)
- Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma (2019) (29)
- Cellular and Tissue Distribution of MRK20 Murine Monoclonal Antibody‐defined 85‐kDa Protein in Adriamycin‐resistant Cancer Cell Lines*1 (1988) (29)
- Adenovirus-mediated lymphotactin gene transfer improves therapeutic efficacy of cytosine deaminase suicide gene therapy in established murine colon carcinoma (2000) (29)
- CD40 Ligand Promotes Priming of Fully Potent Antitumor CD4+ T Cells in Draining Lymph Nodes in the Presence of Apoptotic Tumor Cells (2001) (28)
- Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas (2002) (28)
- Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region (2006) (28)
- Over‐expression of APAF‐1 and caspase‐9 augments radiation‐induced apoptosis in U‐373MG glioma cells (2001) (28)
- Epigenetic Modulation Enhances the Therapeutic Effect of Anti–IL-13Rα2 Antibody in Human Mesothelioma Xenografts (2011) (27)
- The Antiangiogenesis Effect of Interleukin 12 During Early Growth of Human Pancreatic Cancer in SCID Mice (2000) (27)
- Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system (2001) (27)
- Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes (2002) (27)
- Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity (2000) (26)
- Evaluation of selective tumor detection by clinical magnetic resonance imaging using antibody-conjugated superparamagnetic iron oxide. (2012) (26)
- High-level expression of MRK 16 and MRK 20 murine monoclonal antibody-define proteins (170,000-180,000 P-glycoprotein and 85,000 protein) in leukaemias and malignant lymphomas. (1989) (26)
- Determination of membrane antigens by a covalent crosslinking method with monoclonal antibodies. (1987) (25)
- GM‐CSF and B7‐1 (CD80) co‐stimulatory signals co‐operate in the induction of effective anti‐tumor immunity in syngeneic mice (1997) (25)
- Local tumour irradiation enhances the anti‐tumour effect of a double‐suicide gene therapy system in a murine glioma model (2003) (24)
- Adenovirus-mediated transfer of Bcl-X(L) protects neuronal cells from Bax-induced apoptosis. (2000) (24)
- Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis. (2000) (24)
- Multidrug Resistance in Cultured Human Leukemia and Lymphoma Cell Lines Detected by a Monoclonal Antibody, MRK16 (1989) (24)
- EpCAM‐ and EGFR‐targeted selective gene therapy for biliary cancers using Z33‐fiber‐modified adenovirus (2011) (24)
- Adenovirus-mediated transfection of caspase-8 augments anoikis and inhibits peritoneal dissemination of human gastric carcinoma cells. (2001) (24)
- Contribution of KChIP2 to the developmental increase in transient outward current of rat cardiomyocytes. (2003) (24)
- E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer (2009) (23)
- E1A, E1B Double-Restricted Adenovirus with RGD-Fiber Modification Exhibits Enhanced Oncolysis for CAR–Deficient Biliary Cancers (2007) (23)
- Liver retransplantation in children. (1995) (23)
- Progress reports on immune gene therapy for stage IV renal cell cancer using lethally irradiated granulocyte-macrophage colony-stimulating factor-transduced autologous renal cancer cells (2000) (22)
- Mutated focal adhesion kinase induces apoptosis in a human glioma cell line, T98G. (2002) (22)
- Activated dendritic cells from bone marrow cells of mice receiving cytokine-expressing tumor cells are associated with the enhanced survival of mice bearing syngeneic tumors. (1999) (22)
- Construction, propagation, and titer estimation of recombinant adenoviruses carrying proapoptotic genes. (1998) (22)
- Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid. (2002) (21)
- 5‐Fluorouracil efficiently enhanced apoptosis induced by adenovirus‐mediated transfer of caspase‐8 in DLD‐1 colon cancer cells (2003) (21)
- Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration. (2005) (20)
- Effector Cell Analysis of Human Multidrug‐resistant Cell Killing by Mouse‐Human Chimeric Antibody against P‐Glycoprotein (1992) (20)
- Bystander effect in uracil phosphoribosyltransferase/5-fluorouracil-mediated suicide gene therapy is correlated with the level of intercellular communication. (2001) (20)
- Oncolytic viral therapy by bladder instillation using an E1A, E1B double-restricted adenovirus in an orthotopic bladder cancer model. (2006) (20)
- In vivo antitumor effect of cytotoxic T lymphocytes engineered to produce interferon-gamma by adenovirus-mediated genetic transduction. (1996) (20)
- Gene therapy for intraperitoneally disseminated pancreatic cancers by Escherichia coli uracil phosphoribosiltransferase (UPRT) gene mediated by restricted replication‐competent adenoviral vectors (2002) (19)
- Co‐transduction of Apaf‐1 and Caspase‐9 Augments Etoposide‐induced Apoptosis in U‐373MG Glioma Cells (2001) (18)
- Circumvention of 5‐Fluorouracil Resistance in Human Stomach Cancer Cells by Uracil Phosphoribosyltransferase Gene Transduction (1999) (18)
- Adenovirus-mediated gene transfer of Bcl-xL prevents cell death in primary neuronal culture of the rat (1999) (18)
- Enhanced antitumoral effect of adenovirus-mediated cytosine deaminase gene therapy by induction of antigen-presenting cells through stem cell factor/granulocyte-macrophage colony-stimulating factor gene transfer (2000) (18)
- Establishment and characterization of a simian virus 40-immortalized rat pancreatic stellate cell line. (2002) (18)
- Gene transfer of CD40-ligand to dendritic cells stimulates interferon-γ production to induce growth arrest and apoptosis of tumor cells (2008) (18)
- Wnt3 modulates the characteristics and cobblestone area-supporting activity of human stromal cells. (2004) (17)
- Cancer-targeting gene therapy using tropism-modified adenovirus. (2007) (17)
- Oncolytic Herpes Simplex Virus Vectors Fully Retargeted to Tumor- Associated Antigens. (2018) (17)
- Oncolytic virotherapy for prostate cancer by E1A, E1B mutant adenovirus. (2007) (17)
- Recombinant human soluble thrombomodulin for the treatment of hepatic sinusoidal obstructive syndrome post allogeneic hematopoietic SCT (2012) (17)
- A new delivery system for 5-fluorouracil using prodrug and converting enzyme (2002) (17)
- Transduction of KAI1/CD82 cDNA promotes hematogenous spread of human lung‐cancer cells in natural killer cell–depleted SCID mice (2001) (17)
- Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. (2014) (17)
- Enhancement of retrovirus-mediated gene transduction efficiency by transient overexpression of the amphotropic receptor, GLVR-2. (1995) (17)
- In situ generation of pseudotyped retroviral progeny by adenovirus‐mediated transduction of tumor cells enhances the killing effect of HSV‐tk suicide gene therapy in vitro and in vivo (2004) (17)
- Adenovirus‐mediated Transfer of Fas Ligand Gene Augments Radiation‐induced Apoptosis in U‐373MG Glioma Cells (2000) (16)
- Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. (2009) (16)
- Erratum to “BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model” [Molecular Therapy 9: 189–197 (2004), doi:10.1016/j.ymthe.2003.10.012] (2004) (16)
- Amelioration of murine dextran sulfate sodium‐induced colitis by ex vivo extracellular superoxide dismutase gene transfer (2006) (16)
- Inhibition of type I procollagen production by tRNAVal CTE‐HSP47 ribozyme (2003) (16)
- Ex vivo expansion of G-CSF-mobilized peripheral blood CD133+ progenitor cells on coculture with human stromal cells. (2006) (16)
- Further Characterization of the Human Adrenal‐derived P‐GIycoprotein Recognized by Monoclonal Antibody MRK 16 Reacting with Only Human P‐Glycoprotein (1989) (16)
- Short-fiber protein of ad40 confers enteric tropism and protection against acidic gastrointestinal conditions. (2013) (15)
- Caspase-8 gene transduction augments radiation-induced apoptosis in DLD-1 cells. (2002) (15)
- Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter. (2004) (15)
- Adjuvant immunotherapy using fibroblasts genetically engineered to secrete interleukin 12 prevents recurrence after surgical resection of established tumors in a murine adenocarcinoma model. (1999) (15)
- Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limb disease (2009) (15)
- Gene transfer of the CD40‐ligand to human dendritic cells induces NK‐mediated antitumor effects against human carcinoma cells (2007) (15)
- Immunocytochemical Identification and Localization of the Mr 22,000 Calcium‐binding Protein (Sorcin) in an Adriamycin‐resistant Myelogenous Leukemia Cell Line (1989) (15)
- Evidence that the adenoviral vector containing the CTLA4-Ig gene improves transgene expression and graft survival. (1997) (15)
- Comparison of glutathione S-transferase activity between drug-resistant and-sensitive human tumor cells: Is glutathione S-transferase associated with multidrug resistance? (2004) (15)
- Enhanced growth suppression in esophageal carcinoma cells using adenovirus-mediated fusion gene transfer (uracil phosphoribosyl transferase and herpes simplex virus thymidine kinase) (2001) (15)
- Neural cell adhesion molecule 2 as a target molecule for prostate and breast cancer gene therapy (2011) (15)
- Upregulation of p21WAF1/CIP1 leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1 (2001) (14)
- Elimination of drug-resistant myeloma tumor cell lines by monoclonal anti-P-glycoprotein antibody and rabbit complement. (1989) (14)
- Exploration of target molecules for prostate cancer gene therapy (2007) (14)
- IKAROS isoform 6 enhances BCR-ABL1-mediated proliferation of human CD34+ hematopoietic cells on stromal cells. (2011) (14)
- Overexpression of Basic Fibroblast Growth Factor and Bcl-xL with Adenoviral Vectors Protects Primarily Cultured Neurons against Glutamate Insult (2002) (14)
- Myocardial injection of CA promoter‐based plasmid mediates efficient transgene expression in rat heart (2003) (14)
- Oncolytic Virotherapy as a Novel Strategy for Pancreatic Cancer (2004) (14)
- Inhibition of the antigen‐induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI‐P131 and WHI‐P154 in a Janus kinase 3‐independent manner (2005) (14)
- Antitumor effect induced by granulocyte/macrophage-colony-stimulating factor gene-modified tumor vaccination: Comparison of adenovirus- and retrovirus-mediated genetic transduction (2005) (14)
- Changes in N-glycosylation of human stromal cells by telomerase expression. (2003) (14)
- Generation of a Considerable Number of Functional Mast Cells with a High Basal Level of FcɛRI Expression from Cord Blood CD34+ Cells by Co‐culturing Them with Bone Marrow Stromal Cell Line Under Serum‐free Conditions (2007) (14)
- Elevated expression of P-glycoprotein in kidney and urinary bladder cancers. (1991) (14)
- A Novel Multidrug Resistance in Cultured Leukemia and Lymphoma Cells Detected by a Monoclonal Antibody to 85‐kDa Protein, MRK20 (1989) (14)
- Gene therapy for hepatic micrometastasis of murine colon carcinoma. (1998) (13)
- Molecular Cloning and Characterization of the Complementary DNA for the Mr 85,000 Protein Overexpressed in Adriamycin-resistant Human Tumor Cells (1993) (13)
- In vivo retention of endothelial cells adenovirally transduced with tissue-type plasminogen activator and seeded onto expanded polytetrafluoroethylene. (2000) (13)
- Treatment of hepatocellular carcinoma by AdAFPep/rep, AdAFPep/p53, and 5‐fluorouracil in mice (2008) (13)
- Telomerized human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture. (2005) (13)
- Changes in Markers, Receptors and Adhesion Molecules Expressed on Murine Hemopoietic Stem Cells After a Single Injection of 5‐Fluorouracil (1996) (13)
- Human bone marrow stromal cells simultaneously support B and T/NK lineage development from human haematopoietic progenitors: a principal role for flt3 ligand in lymphopoiesis (2012) (13)
- Pr1E11, a novel anti-TROP-2 antibody isolated by adenovirus-based antibody screening, recognizes a unique epitope. (2015) (13)
- Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand. (2005) (12)
- Up-regulation of p21(WAF1/CIP1) levels leads to growth suppression of prostate cancer cell lines. (2002) (12)
- Adenovirus‐mediated Gene Transduction of IkB or IkB Plus Bax Gene Drastically Enhances Tumor Necrosis Factor (TNF)‐induced Apoptosis in Human Gliomas (2000) (12)
- Mouse‐Human Chimeric Antibody MH171 against the Multidrug Transporter P‐Glycoprotein (1992) (12)
- Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients. (1996) (11)
- Transduction of a Fiber‐mutant Adenovirus for the HSVtk Gene Highly Augments the Cytopathic Effect towards Gliomas (2000) (11)
- Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven by a CAG promoter associated with 5-fluorocytosine administration. (2000) (11)
- Expansion of CD34+ Cells on Telomerized Human Stromal Cells without Losing Erythroid-Differentiation Potential in a Serum-Free Condition (2005) (11)
- An advanced strategy of enhanced specific gene expression for hepatocellular carcinoma. (2003) (10)
- E1B-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis. (2005) (10)
- Keratinocyte growth factor regulates proliferation and differentiation of hematopoietic cells expressing the receptor gene K-sam. (2002) (10)
- Adenovirus-mediated transfer of caspase-8 in combination with superrepressor of NF-kappaB drastically induced apoptosis in gliomas. (2000) (10)
- ATP / Mg 2 +-dependent Binding of Vincristine to the Plasma Membrane of Multidrug-resistant K 562 Cells * (2001) (10)
- Tumor-specific chemo-radio-gene therapy for colorectal cancer cells using adenovirus vector expressing the cytosine deaminase gene. (2001) (9)
- E1A, E1B double-restricted adenovirus enhances the cytotoxicity and antitumor activity of gemcitabine to renal cell carcinoma. (2011) (9)
- The potent antitumor effects of combined p16 gene and GM-CSF gene therapy through efficient induction of antitumor immunity (2001) (8)
- Local tumor irradiation augments the anti-tumor effect of cytokine producing autologous cancer cell vaccines in a murine glioma model (2001) (8)
- Caspase-9 Transduction Overrides the Resistance Mechanism against p53-mediated Apoptosis in U-87MG Glioma Cells (2001) (8)
- Spontaneous mutations in the human gene for p53 in recombinant adenovirus during multiple passages in human embryonic kidney 293 cells. (2003) (8)
- Ex Vivo Large Scale Generation of Human Platelets from Cord Blood CD34+ Cells. (2005) (8)
- Growth Inhibition of Multidrug-Resistant Cells by Monoclonal Antibodies against P-Glycoprotein (1991) (8)
- Adenovirus-mediated Transfer of p 33 ING 1 with p 53 Drastically Augments Apoptosis in Gliomas 1 (1999) (8)
- Dual effects of adenovirus-mediated thrombopoietin gene transfer on hepatic oval cell proliferation and platelet counts. (2005) (7)
- Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters (2013) (7)
- Pediatric liver transplantation: effect of the site of arterial inflow on the incidence of hepatic artery thrombosis according to recipient weight. (1994) (7)
- Degree of apoptosis induced by adenovirus-mediated transduction of p53 or p73alpha depends on the p53 status of glioma cells. (2000) (7)
- Gene Transfer of Noncleavable Cell Surface Mutants of Human CD154 Induces the Immune Response and Diminishes Systemic Inflammatory Reactions (2007) (7)
- Dose of Adenoviral Vectors Expressing Interleukin‐2 Plays an Important Role in Combined Gene Therapy with Cytosine Deaminase/5–Fluorocytosine: Preclinical Consideration (2002) (7)
- Adenovirus-Mediated Transduction of Escherichia coli Uracil Phosphoribosyltransferase Gene Increases the Sensitivity of Esophageal Cancer Cells to 5-Fluorouracil (2001) (7)
- Modification of the Rb-binding domain of replication-competent adenoviral vector enhances cytotoxicity against human esophageal cancers via NF-kappaB activity. (2007) (7)
- Adenovirus-mediated gene transfer of CTLA4Ig gene results in prolonged survival of heart allograft (2000) (6)
- Syncytial Mutations Do Not Impair the Specificity of Entry and Spread of a Glycoprotein D Receptor-Retargeted Herpes Simplex Virus (2016) (6)
- Adenovirus-mediated transfer of tissuetype plasminogen activator gene to human endothelial cells (1997) (6)
- Transduction of the human deoxycytidine kinase gene in rodent tumor cells induces in vivo growth retardation in syngeneic hosts. (2000) (6)
- Optimal dose of plasmid vascular endothelial growth factor for enhancement of angiogenesis in the rat brain ischemia model. (2010) (6)
- Co-transduction of p27Kip1 strongly augments Fas ligand- and caspase-8-mediated apoptosis in U-373MG glioma cells. (2001) (6)
- Brain tumor treatment with IL-2 and IL-12 producing autologous cancer cell vaccines. (2001) (6)
- Adenovirus‐mediated gene transfer of basic fibroblast growth factor promotes the survival of primary‐cultured rat neuronal cells (2000) (6)
- Adenovirus-mediated tissue-specific cytosine deaminase gene therapy for human hepatocellular carcinoma with different AFP expression levels. (2002) (6)
- Reduced transduction efficiency of adenoviral vectors expressing human p53 gene by repeated transduction into glioma cells in vitro. (2002) (6)
- Cell Surface Antibody Retention Influences In Vivo Antitumor Activity Mediated by Antibody-dependent Cellular Cytotoxicity. (2016) (6)
- Anti-tumor effect of murine renal cell carcinoma cells genetically modified to express B7-1 combined with cytokine secreting fibroblasts. (2000) (5)
- Gene therapy for murine renal cell carcinoma using genetically engineered tumor cells to secrete interleukin-12. (2000) (5)
- Effects of immunization with tumor cells double transfected with interleukin-2 (IL-2) and interleukin-12 (IL-12) genes on artificial metastasis of colon26 cells in BALB/c mice (1999) (5)
- Adenovirus-mediated gene transfer of CTLA4Ig gene results in prolonged survival of heart allograft. (1998) (5)
- Adenovirus mediated p 53 tumour suppressor gene therapy for human gastric cancer cells in vitro and in vivo (1999) (5)
- Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells. Commentaries (2001) (5)
- A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank (2005) (5)
- Detection of 300-kilodalton membrane protein in adriamycin-resistant human tumor cells by a monoclonal antibody MRK18. (1990) (5)
- De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor‐2 protein (2009) (4)
- Biliary atresia: results of long-term conservative treatment and of liver transplantation. (1993) (4)
- Selective gene transfer into neurons via Na,K‐ATPase β1. Targeting gene transfer with monoclonal antibody and adenovirus vector (2008) (4)
- Molecular cloning and characterization of the complementary DNA for the M(r) 85,000 protein overexpressed in adriamycin-resistant human tumor cells. (1993) (4)
- Adenovirus-mediated transfer of tissue-type plasminogen activator gene to human endothelial cells. (1997) (4)
- Cytokine-gene-modified tumor vaccination intensified by a streptococcal preparation OK-432 (1995) (4)
- Adenovirus-mediated gene transfer of antisense ribozyme for alpha (1,3)galactosyltransferase gene and alpha (1,2)fucosyltransferase gene in xenotransplantation. (1996) (4)
- Prevention of recurrent but not spontaneous autoimmune diabetes by transplanted NOD islets adenovirally transduced with immunomodulating molecules. (2008) (4)
- Effect of antisense ribozyme to alpha (1,3)galactosyl transferase gene on the expression of Gal alpha (1,3)Gal epitope. (1997) (4)
- Effect of glucose and oxygen on the structure of the plasma membrane of Staphylococcus aureus. (1979) (4)
- Chemo-radio-gene therapy for colorectal cancer cells using Escherichia coli uracil phosphoribosyltransferase gene. (2003) (3)
- [Immunological diagnosis of multidrug resistant cancer in urological malignancies]. (1990) (3)
- Polyadenylation signal facilitates the expression of foreign gene that is driven by an internal promoter located in the reverse orientation to long terminal repeat of retrovirus. (2000) (3)
- [Effects of medium chain triglyceride administration on liver regeneration after partial hepatectomy in rats]. (1993) (3)
- Biocompatibility Study of Hemoglobin Vesicles, Cellular-Type Artificial Oxygen Carriers, with Human Umbilical Cord Hematopoietic Stem/Progenitor Cells Using an In Vitro Expansion System (2009) (3)
- Bone Marrow Stromal Cell Line Promotes the Proliferation of Mast Cell Progenitors Derived from Cord Blood CD34+ Cells under Serum-free Conditions with a Combination of Both Cell-cell Interaction and Soluble Factors (2011) (3)
- Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells. (2002) (3)
- Effect of CTLA4-Ig gene transfer using adenoviral vector in organ and cell transplantation. (1997) (3)
- Adenovirus-Mediated Bcl-Xl Gene Therapy Combined with Pronase Treatment Protects the Small Intestine from Radiation-Induced Enteritis in Mouse Model (2014) (3)
- Inhibitory effect of α(1,2) fucosyltransferase recombinant adenoviral vector on αGal expression (1998) (2)
- 12. Therapeutic Potential of the Chimeric Adenovirus 5/40 as Vector for Intestine-Directed Gene Therapy (2006) (2)
- Effectiveness of adenovirus-mediated gene transfer with CTLA4Ig in allo and xeno-transplantation. (2000) (2)
- Adenovirus-mediated gene transfer of antisense ribozyme for α(1,3)galactosyltransferase gene and α(1,2)fucosyltransferase gene in xenotransplantation (1997) (2)
- Manipulation of human early T lymphopoiesis by coculture on human bone marrow stromal cells: potential utility for adoptive immunotherapy. (2013) (2)
- Effect of adenovirus-mediated gene transfer with CTLA4-Ig gene in organ transplantation. (1999) (2)
- Adenovirus-mediated enzyme-prodrug therapy for cancer (1997) (2)
- [Immunogene therapy of cancer using cytokine genes]. (1995) (1)
- [Expression and function of proteins associated with multidrug resistance]. (1989) (1)
- Nucleotide sequences of the variable regions of a mouse monoclonal antibody MRK16. (1990) (1)
- Choledochojejunostomy without stent in pediatric liver transplantation. (1994) (1)
- 771. Adenovirus-Mediated siRNA Against Survivin Enhanced Sensitivity to Paclitaxel-Induced Apoptosis in MCF-7 Cells (2004) (1)
- A novel antitumor effect of water extract from Pleurotus cornucopia that promotes dendritic cell activation and down-regulation of regulatory T cells in tumor-bearing mice (2005) (1)
- A speedy method to detect inserted DNA fragment in cell lines transfected with retroviral vectors (2000) (1)
- Wnt3 Augments Adhesion Mediated Drug Resistance of Myeloma Cells Via Wnt/RhoA Pathway. (2005) (1)
- Therapeutic Implication of Monoclonal Antibodies against Multidrug-Resistant Tumor Cells (1990) (1)
- Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses. (2005) (1)
- Antibody Screening System Using a Herpes Simplex Virus (HSV)-Based Probe To Identify a Novel Target for Receptor-Retargeted Oncolytic HSVs (2021) (1)
- [Detection of multidrug resistant phenotype in leukemia and lymphoma by monoclonal antibodies]. (1988) (1)
- Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-ß2m -/- repopulating cells. Short title for running head: Stem cell expansion by Indian hedgehog (2017) (1)
- Treatment of brain tumors with autologous cancer cell vaccines and radiotherapy (1999) (1)
- 5-Fluorouracil Administration Phosphoribosyltransferase : Significance of Timing of Conditionally Replicative Adenovirus Expressing Uracil Effective Gene Therapy of Biliary Tract Cancers by a (2005) (1)
- Nouvel gene therapy for rheumatoid arthritis by FADD gene transfer (2000) (0)
- Gene Transfer of CD40-Ligand to Human Dendritic Cells Induces Growth Arrest and Apoptosis of Tumor Cells Mediated by Up-Regulated TRAIL and its Receptors. (2004) (0)
- 190. Myocardial Gene Therapy by Naked Angiopoietin-1 Plasmid Injection Efficiently Induces Angiogenesis and Prevents the Remodeling Following Acute Myocardial Infarction (2004) (0)
- Important Role for flt3 Ligand In the Generation of Early B and T Cell Precursors From Human Primitive Hematopoietic Progenitors, Revealed by Telomerized Human Stromal Cells. (2010) (0)
- cancer Pancreas cancer Renal cancer Malignant lymphoma Gastric cancer Neuroblastoma Malignant fibrous histiocytoma Osteogenic sarcoma Lung cancer Ovarian cancer Uterine cervical cancer Smooth muscle sarcoma of the uterus Breast cancer Thymoma (2006) (0)
- RELATIONSHIP BETWEEN KCHIP2 AND TRANSIENT OUTWARD CURRENT OF DEVELOPING RAT HEART (2005) (0)
- Vaccination withirradiated tumorcells engineered tosecrete murinegranulocyte-macrophage colony-stimulati ng factor stimulates potent, specific, andlong-lasting anti-tumor immunity (tumor immunology/gene transfer) GLENNDRANOFF*tt, ELIZABETH JAFFEE§, AUDREYLAZENBY¶, PAULGOLUMBEK§, HYAMLEVITSKY§, (1993) (0)
- 897. Na,K-ATPase β1-Mediated Selective Gene Transfer into Neurons (2006) (0)
- Effect of CTLA4-Ig gene transfer using adenoviral vector in organ and cell transplantation (1996) (0)
- Advances in Brief Adenovirus-mediated Transfection of Caspase-8 Augments Anoikis and Inhibits Peritoneal Dissemination of Human Gastric Carcinoma Cells 1 (2001) (0)
- Wnt3/RhoA/ROCK Signaling Pathway Is Involved in VLA6-Dependent Adhesion-Mediated Drug Resistance of Multiple Myeloma. (2007) (0)
- [Gene therapy and regenerative medicine]. (2002) (0)
- Intracranial murine glioma 261 model to study the antitumor activity of autologous cancer vaccines, producing various cytokines (1997) (0)
- 926. Bcl-xL Gene Transfer Improves Graft Survival and Prolongs the Cold-Preservation Time in the Heart Transplantation (2004) (0)
- P.35 Gene transfer of CD40-ligand to human dendritic cells induces growth arrest and apoptosis of oral squamous cell carcinoma mediated by up-regulated trail and its receptors (2005) (0)
- GENE-MODIFIED MESENCHYMAL STEM CELLS AS CYTOREAGENTS FOR REGENERATIVE THERAPY (2005) (0)
- Soluble Factors Secreted from CD40 Ligand-Transfected Dendritic Cells Enhance TRAIL-Induced Apoptosis of Multiple Myeloma. (2004) (0)
- 938. Myocardial Administration of Adenoviral Vector Encoding VEGF Induces Severe Pleural and Pericardial Effusion in Rat (2004) (0)
- Adenovirus-mediated gene therapy for a murine model of mucopolysaccharidosis type VII : Involvement of in vivo cross-correction of transgene β-glucuronidase and long-term effect of CTLA-4Ig co-expression (1999) (0)
- Indian Hedgehog Stimulates Proliferation of Short-Term NOD/SCID-ß2m null Repopulating Cells on Coculture with Human Stromal Cells. (2004) (0)
- [Gene therapy vector: retroviral vector]. (1997) (0)
- 617 Preclinical animal model of immunogene therapy for lung cancer (1997) (0)
- Suicide gene therapy of gallbladder cancer using a cancer-selectively replicating adenovirus carrrying uracil phosphoribosyltransferase (UPRT) gene (2003) (0)
- 1034 SUPPRESSION OF NEOINTIMA FORMATION AND PDGF RECEPTOR ACTIVITY BY ADENOVIRUS-MEDIATED LOCAL EXPRESSION OF AN EXTRACELLULAR DOMAIN OF PDGF β RECEPTOR (1997) (0)
- INTENSIFIED ANTITUMOR IMMUNOTHERAPY BY CYTOKINE-GENE-MODIFIED TUMOR VACCINES AND CYTOTOXIC LYMPHOCYTES (1995) (0)
- Successful allo-HSCT with a minimal myeloablative conditioning regimen in an adult patient with Fanconi’s anemia (2012) (0)
- 933. Sendai Virus Vector Can Efficiently Introduce Transgene into Cardiomyocytes In Vitro and In Vivo (2004) (0)
- Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID– cells. (2004) (0)
- [Tumor-targeting gene therapy: Ras-dependent oncolytic viral vectors]. (2003) (0)
- Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma (2019) (0)
- Detection of drug resistance in human hematologic malignancy by monoclonal antibodies. (1988) (0)
- 834. Protective Effect of Bcl-XL Gene Expression on the Radiation-Induced Acute Intestinal Injuries (2006) (0)
- Targeting vectors for cancer gene therapy. (2009) (0)
- 189. Sendai Virus Mediated Angiopoietin-1 Gene Therapy for Cardiovascular Diseases (2004) (0)
- Immunological association in anti-tumor effects of thymidine kinase gene therapy in a tumor bearing mouse model with metastasis to lung and liver (1996) (0)
- 587. Artificial Viral-Like Gene Delivery System Multifunctional Envelope-type Nano Device Equipped with Transferrin and a pH-Sensitive Fusogenic Peptide (2005) (0)
- Strategies for specific targeting in cancer gene therapy. (1998) (0)
- Selective gene delivery into target cells by fiber-modified adenovirus (2007) (0)
- Adenovirus-mediated drug-sensitivity gene therapy for hepatocellular carcinoma. (2000) (0)
- [Gene transduction for experimental brain tumors using recombinant adenovirus vector]. (1998) (0)
- Combination Therapy of Humanized Chimeric-Anti-Human VLA4 Monoclonal Antibodies and Anti-Cancer Drugs for AML. (2004) (0)
- Construction and expression of the replication-deficient adenonirus vector of human GM-CSF (1997) (0)
- Tumor Cells Lymph Nodes in the Presence of Apoptotic T Cells in Draining + Potent Antitumor CD4 CD40 Ligand Promotes Priming of Fully (2001) (0)
- Adenovirus‐mediated gene transfer of CTLA4lg gene results in prolonged survival of heart allograft (2000) (0)
- A Novel Non-Cleavable Cell Surface Mutant of CD40-Ligand Induces Anti-Leukemic Immune Response and Prevent Systemic Inflammatory Reaction. (2004) (0)
- CD82 regulates LFA1 activity: Physical and functional association between CD82 and LFA1 (1998) (0)
- Augmented anti-tumor effects of cytotoxic T lymphocytes (CTL) induced by TNF-gene transduced autologous human cancer cells (1995) (0)
- Preparative and Clinical Studies of Immunogene Therapy Using Autologous GM-CSF Transduced Tumor Vaccines for Stage IV Renal Cell Cancer (1999) (0)
- O-9-130 Development of a novel vaccination therapy against malignant gliomas utilizing cytokine-gene transduced tumor cells (1997) (0)
- Bcl-xL gene transfer reduced apoptosis and preseved cardiac function after rat ischemia/reperfusion injury (2004) (0)
- Antitumor Immunity for Peptide Delivery to Induce Specific Dendritic Cells Act as More Potent Adjuvants Lymphotactin Gene-Modified Bone Marrow (1998) (0)
- 19 Transplantation of Sendai Viral Angiopoietin-1-Modified Mesenchymal Stem Cells for Ischemic Heart Disease (2018) (0)
- Angiogenesis and Cardiovascular Regeneration Therapy (2004) (0)
- Target gene therapy for alpha-fetoprotein producing hepatocellular carcinoma by E1B55k-attenuated adenovirus (2001) (0)
- P087 Biosafety and Biodistribution of Chimeric Adenoviruses to the Gastrointestinal Tract: A New Approach to Selective Gene Delivery to the Intestine (2007) (0)
- Gene-Modified Tumor-Primed Lymph Node Specific Effector Cells Generated from Tumor with Poorly Immunogenic Murine Successful Adoptive Immunotherapy (1999) (0)
- [Retrovirus vector]. (1995) (0)
- An E1B-deleted Adenovirus Selectively Kills p53-Deficient Lung Cancer Cells. (1999) (0)
- 300. Gene Therapy for Gastric Cancer Cells Via CEA-Targeted Adv-FZ33 (2006) (0)
- O1-06 Myocardial gene therapy by naked angiopoietin-1 plasmid injection efficiently induces angiogenesis and prevents the remodeling following acute myocardial infarction (2004) (0)
- [Methodology of gene therapy: adverse events and further technological developments]. (2010) (0)
- Selective and Efficient Gene Delivery of CD40-Ligand by a Fiber-Modified Adenovirus Vector with Specific Antibody to Human Leukemia and Myeloma. (2004) (0)
- Inhibitory effect of alpha(1,2) fucosyltransferase recombinant adenoviral vector on alpha Gal expression. (1998) (0)
- Adenoviral Vector-Mediated Transfer of the Indian Hedgehog Gene Modulates Lymphomyelopoiesis In Vivo. (2007) (0)
- Adoptive Immunotherapy with Cytokine Gene-modified Cytotoxic T Lymphocytes (1996) (0)
- Evaluation of Role for flt3L in Human Early B and T/NK Lymphopoiesis in a Novel Stromal Cell Culture System (2011) (0)
- Modulation of Hepatic Sinusoidal Cell Function by Transduction of Genes in the Liver: Gene Therapy for Hepatic Micro-Metastasis (1999) (0)
- Substance de therapie genique contre le cancer, composition medicale et methode therapeutique (1995) (0)
- [Gene program regulating differentiation of embryonal carcinoma cells]. (1996) (0)
- O-2 TARGETED GENE THERAPY FOR CANCERS BY USING Z 33 FIBER MODIFIED ADENOVIRUS VECTOR WITH TUMOR SPECIFIC ANTIBODIES (2009) (0)
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What Schools Are Affiliated With Hirofumi Hamada?
Hirofumi Hamada is affiliated with the following schools: