Hiromitsu Nakauchi
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Biology
Hiromitsu Nakauchi's Degrees
- PhD Biology Stanford University
- Masters Biotechnology University of Tokyo
- Bachelors Biochemistry University of Tokyo
Why Is Hiromitsu Nakauchi Influential?
(Suggest an Edit or Addition)Hiromitsu Nakauchi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Transcriptional Landscape of the Mammalian Genome (2005) (3394)
- The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype (2001) (2338)
- Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell (1996) (1929)
- Frequent pathway mutations of splicing machinery in myelodysplasia (2011) (1799)
- Expression and function of c-kit in hemopoietic progenitor cells (1991) (764)
- Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche (2011) (695)
- Age-Associated Characteristics of Murine Hematopoietic Stem Cells (2000) (679)
- Side population purified from hepatocellular carcinoma cells harbors cancer stem cell–like properties (2006) (675)
- Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells (2013) (568)
- Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. (2004) (557)
- In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. (1992) (538)
- Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. (1995) (525)
- Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells (2010) (486)
- Foxo3a is essential for maintenance of the hematopoietic stem cell pool. (2007) (437)
- Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation (2006) (429)
- Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms (2009) (415)
- Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment (2010) (404)
- Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver (2002) (353)
- Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. (2015) (340)
- Development of Defective and Persistent Sendai Virus Vector (2010) (328)
- Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. (2000) (327)
- Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms (2012) (325)
- In Vitro Self-Renewal Division of Hematopoietic Stem Cells (2000) (322)
- Presence of hematopoietic stem cells in the adult liver (1996) (318)
- Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. (2013) (305)
- TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. (2009) (301)
- Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival. (1991) (299)
- Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells (2010) (298)
- Flow‐cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver (2000) (288)
- Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. (2008) (284)
- Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells. (2014) (276)
- Fcα/μ receptor mediates endocytosis of IgM-coated microbes (2000) (275)
- Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells (2006) (270)
- Hoxb5 marks long-term haematopoietic stem cells revealing a homogenous perivascular niche (2016) (254)
- Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation (1993) (244)
- Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting. (2004) (242)
- Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. (1999) (240)
- Conversion of biliary system to pancreatic tissue in Hes1-deficient mice (2004) (232)
- Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice (2006) (231)
- New ISSCR guidelines underscore major principles for responsible translational stem cell research. (2008) (230)
- CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation (2003) (229)
- Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs (2013) (228)
- Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. (1991) (226)
- De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells (2007) (218)
- Generation of osteoclasts from isolated hematopoietic progenitor cells. (1989) (218)
- Interspecies organogenesis generates autologous functional islets (2017) (216)
- A Role for Pref-1 and HES-1 in Thymocyte Development (2000) (216)
- Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. (2005) (215)
- Essential and Instructive Roles of GATA Factors in Eosinophil Development (2002) (206)
- Hair follicle stem cells provide a functional niche for melanocyte stem cells. (2011) (203)
- Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation. (2007) (202)
- The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. (2008) (201)
- Adult mouse hematopoietic stem cells: purification and single-cell assays (2006) (197)
- The dose dependence of glucocorticoid‐inducible gene expression results from changes in the number of transcriptionally active templates. (1990) (197)
- Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex* (1998) (196)
- Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer (1998) (195)
- Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls (1999) (193)
- A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage (2012) (193)
- Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis (2005) (190)
- Sal‐like protein 4 (SALL4), a stem cell biomarker in liver cancers (2013) (190)
- Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. (2013) (186)
- Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1. (2010) (184)
- Generation of kidney from pluripotent stem cells via blastocyst complementation. (2012) (183)
- Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells (2003) (180)
- Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule (1991) (179)
- Establishment of mouse expanded potential stem cells (2017) (178)
- Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. (2003) (176)
- Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis (2008) (175)
- Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton’s jelly explants of human umbilical cord (2009) (168)
- In vivo self-renewal of c-Kit+ Sca-1+ Lin(low/-) hemopoietic stem cells. (1996) (167)
- Flow cytometric isolation and clonal identification of self‐renewing bipotent hepatic progenitor cells in adult mouse liver (2008) (166)
- A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells (1992) (161)
- HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. (2003) (159)
- Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts. (2010) (157)
- Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction (2007) (155)
- A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. (2006) (153)
- Long-term ex vivo hematopoietic stem cell expansion affords nonconditioned transplantation (2019) (151)
- A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage (2014) (147)
- Human primitive hematopoietic progenitor cells are more enriched in KITlow cells than in KIThigh cells. (1993) (147)
- Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. (2010) (145)
- Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. (2008) (139)
- Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis. (2002) (139)
- Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. (2000) (137)
- Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells. (1992) (129)
- Colony formation of clone-sorted human hematopoietic progenitors. (1990) (128)
- Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation (2016) (128)
- Requirement for CD8 beta chain in positive selection of CD8-lineage T cells. (1994) (127)
- Stem cells and interspecies chimaeras (2016) (126)
- Glucagon-like peptide 1 (1–37) converts intestinal epithelial cells into insulin-producing cells (2003) (126)
- Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. (2007) (118)
- Musculin/MyoR is expressed in kidney side population cells and can regulate their function (2005) (116)
- Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment (2002) (115)
- A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non‐hematopoietic tissues (2001) (114)
- Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia (2004) (113)
- Paired Activating and Inhibitory Immunoglobulin-like Receptors, MAIR-I and MAIR-II, Regulate Mast Cell and Macrophage Activation (2003) (113)
- Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease (2014) (109)
- Developmental Epigenetic Modification Regulates Stochastic Expression of Clustered Protocadherin Genes, Generating Single Neuron Diversity (2014) (109)
- Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. (2009) (108)
- Asymmetric Division and Lineage Commitment at the Level of Hematopoietic Stem Cells (2004) (108)
- Microchimerism in Japanese women patients with systemic sclerosis (1999) (103)
- Revisiting the flight of Icarus: making human organs from PSCs with large animal chimeras. (2014) (103)
- Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment (2018) (102)
- Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice. (2009) (99)
- Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. (1997) (97)
- The Sox-2 Regulatory Regions Display Their Activities in Two Distinct Types of Multipotent Stem Cells (2004) (96)
- Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes. (2013) (94)
- Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells (2012) (93)
- Lymphokine requirement for the generation of natural killer cells from CD34+ hematopoietic progenitor cells. (1995) (93)
- CD226 Mediates Platelet and Megakaryocytic Cell Adhesion to Vascular Endothelial Cells* (2003) (93)
- Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils. (1990) (91)
- Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. (2019) (90)
- Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives (2017) (89)
- Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. (2016) (88)
- Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions (2014) (87)
- Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. (1985) (86)
- Functional characterization of hematopoietic stem cells in the spleen. (2011) (85)
- Role of SOX17 in hematopoietic development from human embryonic stem cells. (2013) (85)
- Interleukin-27 directly induces differentiation in hematopoietic stem cells. (2008) (85)
- Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. (2010) (84)
- Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo (2020) (83)
- In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling. (2012) (82)
- ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021) (82)
- Comparison of Hematopoietic Activities of Human Bone Marrow and Umbilical Cord Blood CD34 Positive and Negative Cells (1999) (82)
- Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development (2005) (81)
- Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. (2009) (80)
- Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold (2018) (75)
- Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls. (1999) (75)
- A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. (1989) (75)
- Do Pluripotent Stem Cells Exist in Adult Mice as Very Small Embryonic Stem Cells? (2013) (75)
- Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats (2019) (75)
- Haematopoietic stem cell self-renewal in vivo and ex vivo (2020) (74)
- Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver. (2000) (73)
- In vivo analysis of Fas antigen-mediated apoptosis: effects of agonistic anti-mouse Fas mAb on thymus, spleen and liver. (1997) (73)
- Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors (2019) (72)
- Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf‐dependent and ‐independent manners in Mice (2010) (72)
- Generation of Germline-Competent Rat Induced Pluripotent Stem Cells (2011) (72)
- Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. (2010) (71)
- Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone. (1985) (71)
- An In Vitro Expansion System for Generation of Human iPS Cell-Derived Hepatic Progenitor-Like Cells Exhibiting a Bipotent Differentiation Potential (2013) (71)
- Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients (2014) (69)
- Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells (2013) (69)
- Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells. (1996) (69)
- Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells (2008) (69)
- The plasminogen fibrinolytic pathway is required for hematopoietic regeneration. (2007) (69)
- Non-side-population hematopoietic stem cells in mouse bone marrow. (2006) (67)
- The Proportion of Fetal Nucleated Red Blood Cells in Maternal Blood: Stimation by FACS Analysis (1997) (67)
- Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. (2018) (67)
- Evidence for Hepatocyte Differentiation from Embryonic Stem Cells In Vitro (2002) (66)
- Targeted organ generation using Mixl1-inducible mouse pluripotent stem cells in blastocyst complementation. (2015) (66)
- IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect. (1993) (66)
- Two alternative forms of cDNA encoding CD34. (1993) (64)
- Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma (2010) (63)
- Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling. (2013) (62)
- Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules. (1992) (61)
- A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy (2015) (61)
- Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing. (2007) (60)
- Analyses of cell surface molecules on hepatic stem/progenitor cells in mouse fetal liver. (2009) (60)
- Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells. (2012) (60)
- Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice. (1996) (59)
- Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder- and Serum-Free Defined Conditions (2010) (57)
- Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase (2011) (56)
- Identification of rat Rosa26 locus enables generation of knock-in rat lines ubiquitously expressing tdTomato. (2012) (56)
- Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes. (2016) (56)
- A melanocyte–melanoma precursor niche in sweat glands of volar skin (2014) (56)
- Il-7 supports D-J but not V-DJ rearrangement of TCR-beta gene in fetal liver progenitor cells. (1996) (56)
- The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells (2013) (56)
- Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product, Bmi-1. (2004) (55)
- Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice. (2018) (55)
- Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma (2010) (55)
- Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease (2009) (54)
- Putative “Stemness” Gene Jam-B Is Not Required for Maintenance of Stem Cell State in Embryonic, Neural, or Hematopoietic Stem Cells (2006) (54)
- Prospero‐related homeobox 1 and liver receptor homolog 1 coordinately regulate long‐term proliferation of murine fetal hepatoblasts (2008) (54)
- Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells (2015) (53)
- Stepwise Development of Hematopoietic Stem Cells from Embryonic Stem Cells (2009) (53)
- Successful multilineage engraftment of human cord blood cells in pigs after in utero transplantation (2003) (53)
- Mac-1(low) early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration. (2004) (53)
- Further Characterization of CD34‐Low/Negative Mouse Hematopoietic Stem Cells (1999) (52)
- Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury (2015) (52)
- Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice. (2012) (52)
- Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells. (2002) (52)
- Beta-chain broadens range of CD8 recognition for MHC class I molecule. (1992) (51)
- Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes (2011) (51)
- Cell cycle dependence of boron uptake from two boron compounds used for clinical neutron capture therapy. (2002) (50)
- Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment (2015) (49)
- Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells (2019) (49)
- CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2017) (48)
- Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo (2006) (48)
- The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery. (2007) (48)
- Quantitative Assessment of the Stem Cell Self‐Renewal Capacity (2001) (48)
- MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells. (2012) (48)
- Induction of M-phase arrest and apoptosis after HIV-1 Vpr expression through uncoupling of nuclear and centrosomal cycle in HeLa cells. (2000) (47)
- Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation (2018) (47)
- Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells (2015) (46)
- Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation (2015) (46)
- A truncated erythropoietin receptor and cell death: a reanalysis. (1994) (46)
- Definitive proof for direct reprogramming of hematopoietic cells to pluripotency. (2009) (45)
- Reconstitution ratio is critical for alloreactive T cell deletion and skin graft survival in mixed bone marrow chimeras. (1995) (45)
- Epigenetic Regulation of Hematopoietic Stem Cell Self-Renewal by Polycomb Group Genes (2005) (45)
- Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia (2014) (44)
- Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals. (2008) (44)
- Homeodomain Transcription Factor Meis1 Is a Critical Regulator of Adult Bone Marrow Hematopoiesis (2014) (43)
- Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL. (2009) (43)
- Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice. (2001) (42)
- Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells (2014) (42)
- Hematopoietic stem cells: Are they CD34-positive or CD34-negative? (1998) (41)
- Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. (1986) (40)
- Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector (2018) (40)
- Inhibition of plasmin protects against colitis in mice by suppressing matrix metalloproteinase 9-mediated cytokine release from myeloid cells. (2015) (40)
- Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus (2016) (40)
- Changes in hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblasts during differentiation. (1993) (40)
- B220 expression by T lymphoid progenitor cells in mouse fetal liver. (1997) (40)
- Long-term ex vivo expansion of mouse hematopoietic stem cells (2020) (39)
- Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells. (2000) (39)
- A chemical probe that labels human pluripotent stem cells. (2014) (39)
- Establishment of rat embryonic stem cell lines that can participate in germline chimerae at high efficiency (2010) (39)
- Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice. (2011) (39)
- Identification and differentiation of hepatic stem cells during liver development. (2006) (38)
- Cytokine Signaling, Lipid Raft Clustering, and HSC Hibernation (2007) (38)
- Support of early B-cell differentiation in mouse fetal liver by stromal cells and interleukin-7. (1991) (38)
- Fcα/µ receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1 (2001) (38)
- Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity. (2017) (38)
- Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells (2012) (38)
- Stem cell therapy: an exercise in patience and prudence (2013) (37)
- Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions. (1987) (36)
- Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice (2020) (36)
- Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin (2014) (36)
- Stage‐Specific Roles for Cxcr4 Signaling in Murine Hematopoietic Stem/Progenitor Cells in the Process of Bone Marrow Repopulation (2014) (35)
- Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. (2016) (35)
- Sequential analysis of hematopoietic reconstitution achieved by transplantation of hematopoietic stem cells. (1993) (35)
- Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation (2019) (35)
- Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells. (2015) (35)
- Potent vaccine therapy with dendritic cells genetically modified by the gene-silencing-resistant retroviral vector GCDNsap. (2006) (35)
- Generation of Recombination Activating Gene-1-Deficient Neonatal Piglets: A Model of T and B Cell Deficient Severe Combined Immune Deficiency (2014) (34)
- Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome. (2017) (34)
- Detection of fetal HPCs in maternal circulation after delivery (2001) (33)
- T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera. (2009) (33)
- A mouse carrying genetic defect in the choice between T and B lymphocytes. (1998) (33)
- Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. (1992) (33)
- Development of an All-in-One Inducible Lentiviral Vector for Gene Specific Analysis of Reprogramming (2012) (33)
- Changing concepts in hematopoietic stem cells (2018) (32)
- Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking (2014) (32)
- Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. (2009) (32)
- An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors (2017) (32)
- Deregulated Intracellular Signaling by Mutated c-CBL in Myeloid Neoplasms (2010) (32)
- Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins (2016) (31)
- Rat transgenesis via embryonic stem cells electroporated with the Kusabira‐orange gene (2010) (31)
- Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes (2019) (30)
- Liver repopulation by c-Met-positive stem/progenitor cells isolated from the developing rat liver. (2004) (30)
- Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation (2016) (30)
- Novel strategies for liver therapy using stem cells (2014) (29)
- The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer (2012) (29)
- Long-Term Culture of Fetal Liver Cells Using a Three-Dimensional Porous Polymer Substrate (2000) (29)
- Molecular evidence that SJL reticulum cell sarcomas are derived from pre-B cell. Clonal rearrangement of heavy chain but not of light chain immunoglobulin genes. (1987) (28)
- Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies (2014) (28)
- Prospective isolation and characterization of bipotent progenitor cells in early mouse liver development. (2012) (28)
- Somatic Gene Therapy for Diabetes With an Immunological Safety System for Complete Removal of Transplanted Cells (1992) (28)
- Self-renewal and lineage restriction of hematopoietic stem cells. (2003) (27)
- TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Commentary (2009) (27)
- An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70. (1998) (26)
- iPSC-Derived Organs In Vivo: Challenges and Promise. (2018) (26)
- In Vitro Production of Functionally Mature Hepatocytes from Prospectively Isolated Hepatic Stem Cells (2003) (26)
- CD 226 ( DNAM-1 ) Is Involved in Lymphocyte Function – associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation (2003) (26)
- The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs. (2014) (26)
- Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b+/F4/80+ myeloid cell recruitment (2012) (26)
- Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns (2013) (26)
- Interspecies chimeras. (2018) (25)
- In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma (2017) (25)
- Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3 (2014) (25)
- A Comprehensive System for Generation and Evaluation of Induced Pluripotent Stem Cells Using piggyBac Transposition (2014) (25)
- The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells. (2011) (25)
- Insights into signaling and function of hematopoietic stem cells at the single-cell level (2009) (24)
- Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds (2019) (24)
- Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. (2005) (24)
- Establishment of Clonal Colony-Forming Assay System for Pancreatic Stem/Progenitor Cells (2002) (24)
- Binding of c-Myb to the core sequence of the CD4 promoter. (1993) (24)
- Recent duplication of the two human CD8 beta-chain genes. (1992) (24)
- Effects of interleukin 3, interleukin 6, and granulocyte colony-stimulating factor on sorted murine splenic progenitor cells. (1991) (24)
- CD4dull+ hematopoietic progenitor cells in murine bone marrow (1993) (23)
- Synergistic effect of IL-3 and IL-6 on highly enriched murine hemopoietic progenitors. (1992) (23)
- Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress. (2018) (23)
- Plenary Lecture (2017) (23)
- Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells (2013) (23)
- Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity (2018) (22)
- Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11. (1988) (22)
- T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung. (2015) (22)
- Full reconstitution of hematopoietic system by murine umbilical cord blood (2003) (22)
- Lessons from Interspecies Mammalian Chimeras. (2017) (22)
- Generation of Col2a1-EGFP iPS Cells for Monitoring Chondrogenic Differentiation (2013) (22)
- Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow (1993) (22)
- Establishment and functional analysis of a cloned, antigen-specific suppressor effector T cell line. (1984) (22)
- Characterization of the ICSI‐mediated gene transfer method in the production of transgenic pigs (2012) (21)
- Pre‐Transplantation Blockade of TNF‐α‐Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells (2017) (21)
- Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera. (2011) (21)
- Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells. (2012) (21)
- Interspecies chimeras for human stem cell research (2017) (21)
- Comparative structure of two duplicated T1a class I genes (T10c and 37) of the murine H-2d MHC. Implications on the evolution of the T1a region. (1990) (21)
- Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. (2013) (21)
- A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells (2008) (21)
- Efficient scarless genome editing in human pluripotent stem cells (2018) (21)
- Role of c-jun in the inhibition of erythropoietin receptor-mediated apoptosis. (1996) (21)
- Bone marrow Schwann cells induce hematopoietic stem cell hibernation (2014) (20)
- In vivo haematopoietic potential of human neural stem cells (2005) (20)
- Treatment of a genetic brain disease by CNS-wide microglia replacement (2022) (20)
- Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts (2014) (20)
- An interspecies barrier to tetraploid complementation and chimera formation (2018) (20)
- Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1 (2015) (20)
- Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras. (2020) (20)
- Identification and propagation of liver stem cells. (2002) (20)
- Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep (2018) (20)
- Parvovirus Nonstructural Proteins Induce an Epigenetic Modification through Histone Acetylation in Host Genes and Revert Tumor Malignancy to Benignancy (2005) (20)
- Lift NIH restrictions on chimera research. (2015) (19)
- In vivo stem cell function of interleukin-3-induced blast cells. (1991) (19)
- Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. (1987) (19)
- The Actin Polymerization Regulator WAVE2 Is Required for Early Bone Marrow Repopulation by Hematopoietic Stem Cells (2009) (19)
- 'Off-the-shelf' immunotherapy with iPSC-derived rejuvenated cytotoxic T lymphocytes. (2017) (19)
- Thy-1 as a negative growth regulator in ras-transformed mouse fibroblasts. (1991) (19)
- Cyclosporin A inhibits the decrease of CD4/CD8 expression induced by protein kinase C activation. (1993) (18)
- Human immunodeficiency virus type 2 envelope glycoprotein binds to CD8 as well as to CD4 molecules on human T cells (1997) (18)
- Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples. (2014) (18)
- Reprogramming adult hematopoietic cells (2010) (18)
- Modeling lethal X-linked genetic disorders in pigs with ensured fertility (2018) (18)
- Increased cell surface expression of C‐terminal truncated erythropoietin receptors in polycythemia (2001) (18)
- CD4 and CD8 regulate interleukin 2 responses of T cells. (1992) (18)
- Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats (2021) (17)
- Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain. (2006) (17)
- Constant delivery of proinsulin by encapsulation of transfected cells. (1997) (17)
- Gene Targeting Study Reveals Unexpected Expression of Brain-expressed X-linked 2 in Endocrine and Tissue Stem/Progenitor Cells in Mice* (2014) (17)
- "Homing to Niche," a new criterion for hematopoietic stem cells? (2004) (17)
- Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2017) (17)
- Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth. (2015) (17)
- Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells (2014) (17)
- Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells (2012) (16)
- Different effects of substitutions at residues 224 and 228 of MHC class I on the recognition of CD8. (1993) (16)
- Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice (2013) (16)
- Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments. (1989) (16)
- Evidence for the presence of hematopoietic stem cells in the adult liver. (1995) (16)
- Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (16)
- Enzyme augmentation therapy enhances the therapeutic efficacy of bone marrow transplantation in mucopolysaccharidosis type II mice. (2014) (16)
- Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells (1997) (15)
- A retrospective analysis of germline competence in rat embryonic stem cell lines (2013) (15)
- Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow. (1993) (15)
- Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cells. (2016) (15)
- Fc(alpha)/mu receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1. (2001) (15)
- A quantitative analysis of cell surface glycosphingolipid with a fluorescence activated cell sorter. (1983) (15)
- Transgenic Pigs with Pancreas-specific Expression of Green Fluorescent Protein (2014) (15)
- Usefulness of flow-cytometric cell sorting for enrichment of hepatic stem and progenitor cells in the liver. (2000) (15)
- Bone marrow chimerism prevents atherosclerosis in arterial walls of mice deficient in apolipoprotein E. (2002) (15)
- Generation of Mouse Functional Oocytes in Rat by Xeno-Ectopic Transplantation of Primordial Germ Cells1 (2014) (14)
- A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease (2017) (14)
- Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. (2017) (14)
- CD4dull+ hematopoietic progenitor cells in murine bone marrow. (1993) (14)
- FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells. (2010) (14)
- Non-myeloablative preconditioning with ACK2 (anti-c-kit antibody) is efficient in bone marrow transplantation for murine models of mucopolysaccharidosis type II. (2016) (14)
- Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL. (2012) (14)
- LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells (2019) (14)
- Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83. (2000) (14)
- Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system (2016) (13)
- High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis (2021) (13)
- CD3‐induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor (1996) (13)
- The basic helix-loop-helix transcription factor, Mist1, induces maturation of mouse fetal hepatoblasts (2015) (13)
- Characterization of the mouse interleukin-13 receptor α1 gene (2000) (13)
- A Comparison of the Rest Complex Binding Patterns in Embryonic Stem Cells and Epiblast Stem Cells (2014) (13)
- Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells. (2021) (13)
- Stabilizing hematopoietic stem cells in vitro. (2020) (13)
- Rapid T‐cell chimerism switch and memory T‐cell expansion are associated with pre‐engraftment immune reaction early after cord blood transplantation (2013) (13)
- Isolation and Clonal Characterization of Hematopoietic and Liver Stem Cells (2004) (13)
- Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms (2010) (12)
- New Type of Matrix Support for Bone Marrow Cell Cultures:In Vitro Culture and In Vivo Transplantation Experiments (2000) (12)
- Application of Droplet Digital PCR for Estimating Vector Copy Number States in Stem Cell Gene Therapy (2016) (12)
- Analyses of adult T-cell leukemia using the monoclonal (anti-Leu-1, anti-Leu-2a, and anti-Leu-3a) and heterologous anti-glycolipid (anti-asialo GM1) antibodies. (1982) (12)
- Impaired erythropoiesis in transgenic mice overexpressing a truncated erythropoietin receptor. (1998) (12)
- Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease (2014) (12)
- Treatment of diabetic mice with encapsulated fibroblasts producing human proinsulin. (1992) (12)
- An improved method to make sequential deletion mutants for DNA sequencing. (1989) (12)
- Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA (2018) (12)
- An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2 (2008) (12)
- The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells (2014) (12)
- Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method (2017) (12)
- Generation of B lymphocytes from a single hemopoietic progenitor cell in vitro. (1991) (12)
- Ability of tetraploid rat blastocysts to support fetal development after complementation with embryonic stem cells (2012) (12)
- CD 226 Mediates Platelet and Megakaryocytic Cell Adhesion to Vascular Endothelial Cells * (2003) (11)
- In vitro expansion and functional recovery of mature hepatocytes from mouse adult liver (2012) (11)
- Fractalkine shares signal sequence with TARC: gene structures and expression profiles of two chemokine genes. (2001) (11)
- Characterization of an antigen-specific suppressive factor derived from a cloned suppressor effector T cell line. (1984) (11)
- Recipient-derived cells after cord blood transplantation: dynamics elucidated by multicolor FACS, reflecting graft failure and relapse. (2008) (11)
- Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species (2021) (11)
- Control of cell growth and differentiation during early B-cell development by stromal cell molecules. (1989) (11)
- Role of a truncated erythropoietin receptor for erythroid differentiation. (1996) (11)
- Stable transgene expression in mice generated from retrovirally transduced embryonic stem cells. (2007) (11)
- Antigen recognition by the T cell receptor is enhanced by CD8 α-chain binding to the α3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8α (1992) (11)
- Glycosphingolipids of rat T cells. Predominance of asialo-GM1 and GD1c. (1994) (11)
- Diff erential impact of Ink 4 a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi 1-defi cient mice (2006) (11)
- Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. (2019) (11)
- Clonal Expansion of Hepatic Stem/Progenitor Cells following Flow Cytometric Cell Sorting (2001) (10)
- Hedgehog Activation Regulates Human Osteoblastogenesis (2020) (10)
- Germline development in rat revealed by visualization and deletion of Prdm14 (2020) (10)
- Use of cell type‐specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development (2014) (10)
- Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers (2020) (10)
- Sustainable Tumor-Suppressive Effect of iPSC-Derived Rejuvenated T Cells Targeting Cervical Cancers (2020) (10)
- Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo (2019) (10)
- MEK-ERK Activity Regulates the Proliferative Activity of Fetal Hepatoblasts Through Accumulation of p16/19(cdkn2a). (2015) (10)
- Isolation of Murine Hematopoietic Stem Cells and Progenitor Cells (2005) (10)
- Unique composition of polycomb repressive complex 1 in hematopoietic stem cells (2007) (10)
- Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing (2009) (10)
- Engraftment of human myelodysplastic syndrome derived cell line in transgenic severe combined immunodeficient (TG‐SCID) mice expressing human GM–CSF and IL‐3 (1998) (10)
- Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (10)
- Molecular cloning and characterization of mouse Tspan-3, a novel member of the tetraspanin superfamily, expressed on resting dendritic cells. (2001) (10)
- Multicolor Flow‐Cytometric, Morphologic, and Clonogenic Analysis of Marrow CD10‐Positive Cells in Children With Leukemia in Remission or Nonmalignant Diseases (1998) (9)
- Prolonged survival of dog kidney allografts induced by a monoclonal anti-Ia antibody. (1984) (9)
- Mouse immunoglobulin allotypes: multiple differences between the nucleic acid sequences of the IgEaand IgEballeles (2004) (9)
- ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts (2021) (9)
- New type of matrix support for bone marrow cell cultures: in vitro culture and in vivo transplantation experiments. (1999) (9)
- Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. (2019) (9)
- Immunoglobulin levels in patients on long-term hemodialysis. (1981) (9)
- Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2014) (9)
- Chimeric liver transplantation reveals interspecific graft remodelling. (2018) (9)
- Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. (2019) (9)
- Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications (2018) (9)
- Isolation of a cDNA encoding a tyrosine kinase expressed in murine skin (1997) (9)
- Practical selection methods for rat and mouse round spermatids without DNA staining by flow cytometric cell sorting (2016) (9)
- Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis. (2012) (9)
- Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6 (2018) (8)
- Polycomb gene product Bmi-1 regulates stem cell self-renewal. (2005) (8)
- Single-cell analysis of mitochondrial DNA in patients and a carrier of the tRNALeu(UUR) gene mutation (1999) (8)
- Clonogenic Colony-Forming Ability of Flow Cytometrically Isolated Hepatic Progenitor Cells in the Murine Fetal Liver (2000) (8)
- Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. (2014) (8)
- Functional primordial germ cell–like cells from pluripotent stem cells in rats (2022) (8)
- Clonal colony formation of hepatic stem/progenitor cells enhanced by embryonic fibroblast conditioning medium. (2000) (8)
- DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells (2014) (8)
- Evidence for the presence of hepatic stem cells in the murine fetal liver. (1999) (8)
- The generation and maintenance of rat induced pluripotent stem cells. (2014) (8)
- Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts (2019) (8)
- Cloning of Homozygous a1,3-Galactosyltransferase Gene Knock-Out Pigs by Somatic Cell Nuclear Transfer (2012) (8)
- Duplication of the CD8 beta-chain gene as a marker of the man-gorilla-chimpanzee clade. (1993) (7)
- A novel stromal cell-dependent B lymphoid stem-like cell line that induces immunoglobulin gene rearrangement. (1999) (7)
- Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease (2011) (7)
- Loss of ganciclovir sensitivity by exclusion of thymidine kinase gene from transplanted proinsulin-producing fibroblasts as a gene therapy model for diabetes. (1996) (7)
- Effect of donor chimerism to reduce the level of glycosaminoglycans following bone marrow transplantation in a murine model of mucopolysaccharidosis type II (2015) (7)
- Investigation of Cas9 antibodies in the human eye (2022) (7)
- Restricting Elements in the Immunological Circuitry: the Role of I Region‐Controlled Determinants (1983) (7)
- Hepatic stem/progenitor cells with high proliferative potential in liver organ formation. (2001) (7)
- T-cell subsets in patients with gastric cancer. (1985) (7)
- Differential Level in Co‐Down‐Modulation of CD4 and CXCR4 Primed by HIV‐1 gp120 in Response to Phorbol Ester, PMA, among HIV‐1 Isolates (2000) (7)
- Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. (2016) (7)
- An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils (2015) (7)
- Evidence for the existence of two parallel differentiation pathways in the thymus of MRL lpr/lpr mice. (1992) (7)
- Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses (2022) (7)
- Effective treatment against severe graft-versus-host disease with allele-specific anti-HLA monoclonal antibody in a humanized mouse model. (2015) (7)
- Anephrogenic phenotype induced by SALL1 gene knockout in pigs (2019) (7)
- Designing Motif-Engineered Receptors To Elucidate Signaling Molecules Important for Proliferation of Hematopoietic Stem Cells. (2018) (7)
- Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells (2017) (7)
- Structure and expression of the gene encoding CD8α chain (Leu-2/T8) (1989) (6)
- Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells. (2015) (6)
- Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (6)
- Clonal deletion of thymic mature T cells induced by staphylococcal enterotoxin B in murine fetal thymus organ culture (1993) (6)
- Chemically defined cytokine-free expansion of human haematopoietic stem cells (2023) (6)
- Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (6)
- Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo (2021) (6)
- Antigen recognition by the T cell receptor is enhanced by CD8 alpha-chain binding to the alpha 3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8 alpha. (1992) (6)
- Xenotransplantation and interspecies organogenesis: current status and issues (2022) (6)
- Effects of combined growth factors on clonal growth and albumin secretion of murine fetal hepatocytes in low density culture. (2000) (6)
- Clonogenic colony-forming ability of flow cytometrically isolated hepatic progenitor cells in the murine fetal liver. (2000) (6)
- Proliferative and functional ability of transplanted murine neonatal hepatocytes in adult livers. (2000) (6)
- MHC gene Q8/9d of the BALB/cJ mouse strain cannot encode a Qa-2,3 class I antigen (2004) (5)
- Principles of Hematopoietic Stem Cell Biology (2010) (5)
- Early B Cell Differentiation from Hematopoietic Stem Cells in the Presence of Stromal Cells and Interleukin-7 (IL-7) (1990) (5)
- Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma. (2021) (5)
- Immunological barriers to haematopoietic stem cell gene therapy (2022) (5)
- In vivo hematopoietic potential of human neuronal stem cells (2000) (5)
- Knock‐in of a histone H2B‐tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats (2015) (5)
- Germline development in rat revealed by visualization and deletion of Prdm14. (2020) (5)
- Identification and characterization of in vitro expanded hematopoietic stem cells (2022) (5)
- Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation (2016) (5)
- Hematopoietic Stem Cells in the Mouse Spleen (2008) (5)
- Multipotent and Committed CD34+ Cells in Bone Marrow Transplantation (1991) (5)
- An in vivo assay for retrovirally transduced human peripheral T lymphocytes using nonobese diabetic/severe combined immunodeficiency mice. (2005) (5)
- Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells. (2013) (5)
- The distinct subgroup of patients with rheumatoid arthritis shown by Ig G3-reactive rheumatoid factor. (1989) (5)
- Dominant expansion of human T cells in non-obese diabetic/severe combined immunodeficiency mice implanted with human bone fragments. (2000) (5)
- Cross-species blastocyst chimerism between nonhuman primates using iPSCs (2019) (5)
- Control of proinsulin production by sense-anti-sense regulation in response to glucocorticoids. (1996) (5)
- Molecular cloning, reconstruction and expression of the gene encoding the alpha-chain of the bovine CD8--definition of three peptide regions conserved across species. (1992) (4)
- Quantification of adult T-cell leukemia/lymphoma cells using simple four-color flow cytometry (2015) (4)
- iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma (2021) (4)
- Single amino acid substitution in the V3 domain of CD4 is responsible for OKT4 epitope deficiency (2004) (4)
- Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors (2017) (4)
- Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells (2011) (4)
- Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation (2022) (4)
- Effects of four extracellular matrices associated with growth factors on clonal culture and proliferation of murine fetal hepatocytes. (2000) (4)
- Expression of Leu M1 antigen on a monoclonal B cell line established from a patient with rheumatoid arthritis. (1989) (4)
- Advances in Allogeneic Cancer Cell Therapy and Future Perspectives on “Off-the-Shelf” T Cell Therapy Using iPSC Technology and Gene Editing (2022) (4)
- Specific amino acid environments of bone marrow are crucial for the maintenance of hematopoietic stem cells (2015) (4)
- Characterization of hematopoietic stem cells in the adult liver. (1997) (4)
- Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts (2017) (4)
- Extent of chimerism determines the mode of tolerance in mixed bone marrow chimeras. (1997) (4)
- 1107. Gene Therapy Clinical Trials for Relapsed Leukemia with Infusions of the Suicide-Gene Transduced Donor Lymphocytes in Japan (2006) (4)
- Expression and function of the transfected CD8 alpha chain in murine T cell hybridomas. (1990) (3)
- Rat Blastocysts from Nuclear Injection and Time-Lagged Enucleation and Their Commitment to Embryonic Stem Cells. (2016) (3)
- Investigation of bipotent differentiation of hepatoblasts using inducible diphtheria toxin receptor‐transgenic mice (2016) (3)
- The role of peripheral blood T and B lymphocytes in mitogen responses during human pregnancy. (1985) (3)
- Enrichment and clonal culture of hepatic stem/progenitor cells during mouse liver development. (2013) (3)
- A human cell line of chronic myelogenous leukemia releasing a novel virus-like particle. (1988) (3)
- Five-lineage clonal analysis of hematopoietic stem/progenitor cells. (2014) (3)
- Abstract 5119: Frequent splicing pathway mutations and aberrant RNA splicing in myelodysplasia (2012) (3)
- Autosomal codominant inheritance and Japanese incidence of deficiency of OKT4 epitope with lack of reactivity resulting from conformational change. (1993) (3)
- [From cell therapy to organ regeneration therapy: generation of functional organs from pluripotent stem cells]. (2011) (3)
- Expression of Rh blood group gene transcripts in human leukocytes. (1994) (3)
- [Generation of functional organs from pluripotent stem cells]. (2013) (3)
- Human Immunodeficiency Virus Type 1 Vpr Modifies Cell Proliferation via Multiple Pathways (1999) (2)
- Thy-1 inhibits mitogen-induced Ca2+ oscillation in ras-transformed mouse fibroblasts. (1992) (2)
- A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice (2007) (2)
- Reactive oxygen species in hematopoietic stem cells affect culture outcomes under inflammatory conditions (2015) (2)
- Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells (2011) (2)
- Stepwise Signaling and Low Oxygen Promote Hematopoietic Progenitor Emergence From Human Pluripotent Stem Cells (2011) (2)
- CRISPR/Cas9 + AAV-mediated Intra-embryonic Gene Knocking in Mice. (2019) (2)
- Bloodlines of haematopoietic stem cell research in Japan (2008) (2)
- Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. (2019) (2)
- Chimpanzee and pig-tailed macaque iPSCs: Improved culture and generation of primate cross-species embryos. (2022) (2)
- Single-cell analysis identifies EpCAM+/CDH6+/TROP-2− cells as human liver progenitors (2018) (2)
- A transmembrane trap method for efficient cloning of genes encoding proteins possessing transmembrane domain. (2001) (2)
- Altered Immune Responsiveness in Patients with Chronic Glomerulonephritis (1989) (2)
- 30 – Phenotype of Mouse Hematopoietic Stem Cells (2004) (2)
- Development A Role for Pref-1 and HES-1 in Thymocyte (1999) (2)
- Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice (2015) (2)
- A highly efficient reporter system for identifying and characterizing in vitro expanded hematopoietic stem cells (2021) (2)
- Establishment in Culture of Expanded Potential Stem Cells (2017) (2)
- Streamlined and quantitative detection of chimerism using digital PCR (2022) (2)
- 73 APPLICATION OF THE HOLLOW FIBER VITRIFICATION METHOD TO THE CRYOPRESERVATION OF HIGHLY CRYOSENSITIVE EMBRYOS (2015) (2)
- Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells (2020) (2)
- The cytoplasmic domain of the CD8 α-chain is required for its interaction with p56lck (1990) (2)
- [Isolation and characterization of the hematopoietic stem cell]. (1995) (2)
- Genetically engineered pigs manifesting pancreatic agenesis with severe diabetes (2020) (2)
- Structure and expression of the gene encoding CD8 alpha chain (Leu-2/T8). (1989) (2)
- 326 GENERATION OF A DOUBLE-TRANSGENIC PIG WITH PANCREAS-SPECIFIC GREEN AND LIVER-SPECIFIC RED FLUORESCENCE (2013) (1)
- Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner. (2015) (1)
- Functional Analysis of SRSF2 Mutations in Myelodysplastic Syndromes and Related Disorders (2011) (1)
- Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo. (2009) (1)
- Removal of sperm tail using trypsin and pre-activation of oocyte facilitates intracytoplasmic sperm injection in mice and rats (2022) (1)
- Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma (2011) (1)
- Characterization of the mouse interleukin-13 receptor alpha1 gene. (2000) (1)
- Evidence for the Involvement of CXCR4 Signaling in In Vivo Self-Renewal of Transplanted Hematopoietic Stem Cells (2011) (1)
- Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2020) (1)
- Generation of Blood Cells from Human Ips Cells in Vitro through the Hematopoietic Progenitors Concentrated within the Unique Structures, Ips-Sac. (2008) (1)
- Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease (2015) (1)
- In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation (2022) (1)
- Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation (2020) (1)
- Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells. (2016) (1)
- Epigenetic Memory Enables the Dominant Generation of Adult-Type Erythrocytes From Human Induced Pluripotent Stem Cells (2010) (1)
- Identification of a Novel cDNA Clone Encoding Protein Tyrosine Kinase in Murine Skin (1994) (1)
- In vivo and ex vivo haematopoietic stem cell expansion. (2020) (1)
- Streamlined and quantitative detection of chimerism in mouse tissue using digital PCR (2020) (1)
- Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation (2011) (1)
- Ex vivo mouse hematopoietic stem cell expansion using polyvinyl alcohol (2019) (1)
- Use of polyvinyl alcohol for CAR T cell expansion (2020) (1)
- A truncated erythropoietin receptor as a dominant negative regulator for cell growth and prevention of apoptosis (1994) (1)
- [Potential usefulness of human iPS cells on the generation of platelets]. (2011) (1)
- strain cannot encode a (1991) (1)
- The Cytokine Signal Inhibitor Lnk Promotes αIIbβ3 Integrin Outside-In Signaling through β3 Tyrosine Phosphorylation in Platelets. (2007) (1)
- A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice (2008) (1)
- MT1-MMP Is Required for Hematopoietic Maturation in the BM Niche. (2009) (1)
- Biological Analysis of SRSF2 Mutations in Leukemogenesis (2012) (1)
- 49 PRACTICAL APPLICATION OF THE HOLLOW FIBER VITRIFICATION METHOD FOR CRYOPRESERVATION OF MAMMALIAN EMBRYOS (2014) (1)
- In vivo clonal analysis of aging hematopoietic stem cells (2020) (1)
- Improving the safety of iPSC-derived T cell therapy (2022) (1)
- A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies. (2009) (1)
- HEMATOPOIESIS AND STEM CELLS Role of SOX 17 in hematopoietic development from human embryonic stem cells (2013) (1)
- Hematopoietic stem cell chimerism: relationships between degree of chimerism, T cell clonal deletion, and graft survival. (1994) (1)
- CD61/ Integrin β3 Ligation Contributes to the Thrombopoietin-Mediated Niche Function of Mouse Hematopoietic Stem Cells. (2009) (1)
- Characterization of the mouse CD8 beta chain-encoding gene promoter region (2007) (1)
- Hematopoietic Stem Cells for Regenerative Medicine (2009) (1)
- The cytoplasmic domain of the CD8 alpha-chain is required for its interaction with p56lck. (1990) (1)
- M2 macrophage exosomes regulate hematopoiesis & resolve inflammation in atherosclerosis via microrna cargo (2020) (1)
- Corrigendum to “Cell cycle dependence of boron uptake from two boron compounds used for clinical neutron capture therapy” [Cancer Lett. 187 (2002) 135–141] (2005) (1)
- Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells. (2009) (0)
- DOWN-REGULATION OF SALL4 INHIBITS TUMOR GROWTH IN HEPATOCELLULAR CARCINOMA (2010) (0)
- Title Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells (2019) (0)
- Twelve-color Chimerism Analysis after HLA-mismatched Hematopoietic Cell Transplantation Using Anti-HLA Antibody and Spectral Flow Cytometer (2012) (0)
- Abstract 17293: Hyperglycemia Enhances Pro-Inflammatory Properties of Macrophage-Derived Exosomes to Drive Hematopoiesis in Apolipoprotein E-Deficient Mouse (2020) (0)
- Response : A Truncated Erythropoietin Receptor and Cell Death (1993) (0)
- 3103 – DEVELOPMENT OF EX VIVO HEMATOPOIETIC STEM CELL ASSAYS USING A HIGHLY SELECTIVE EXPANSION SYSTEM (2022) (0)
- Transfusion therapy by blood platelets derived from embryonic stem cells or induced pluripotent stem cells (2008) (0)
- Expression of Endomucin, a CD34-Like Sialomucin, Marks Definitive Hematopoietic Stem Cells throughout Development. (2004) (0)
- Abstract 4602: Recurrent pathway mutations of multiple components of cohesin complex in myeloid neoplasms. (2013) (0)
- Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Patients with Down Syndrome (2010) (0)
- Analysis of Physical Characteristic of Hematopoietic Cells (2015) (0)
- Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins (2016) (0)
- Tmtsp , a Novel Gene Encoding a Cell Surface Protein Highly Specific to Hematopoietic Stem and Endothelial Cells. (2004) (0)
- Use of Animal Models for the Study of Stem Cell Biology (2009) (0)
- Abstract 408: ApoE Regulation of Hematopoiesis Suppresses Atherosclerosis by Reducing Adaptive Immunity in Hyperlipidemic Mice (2018) (0)
- Mechanical guidance of self-condensation patterns of differentiating progeny (2022) (0)
- Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes (2021) (0)
- Development of Antigen Specific T Cells After HLA-Mismatched Umbilical Cord Blood Transplantation (2011) (0)
- Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin (2010) (0)
- Selective Activation of STAT5 Unveils Its Role in the Maintenance of Hematopoietic Stem Cells and the Development of Myeloproliferative Disorder. (2004) (0)
- Lymphoid Lineage Restriction in Hematopoietic Stem Cells through Their First Division. (2004) (0)
- [Diversity of hematopoietic stem cells]. (2005) (0)
- Author Correction: Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2018) (0)
- Author Correction: Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2018) (0)
- Role Of Sf3b1 On Hematopoiesis (2013) (0)
- Maintenance and expansion of human hematopoietic stem and progenitor cells in the presence of defined factors alone (2015) (0)
- Mammalian epigenetics in biology and medicine ’ . Subject Areas : health and disease and epidemiology Keywords : stem cells , pluripotency , induced pluripotent stem cells , embryonic stem cells (2012) (0)
- In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation (2022) (0)
- Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (0)
- Efficient genaration of rabbit pluripotent stem cells (2017) (0)
- Single amino acid substitutions determine mouse CD8 allotypes: epitope mapping of mouse CD8 (2005) (0)
- 3017 – ESTABLISHMENT OF A PLATFORM FOR EX VIVO GENE EDITING IN MULTIPOTENT HEMATOPOIETIC STEM CELLS (2021) (0)
- Irradiated Bone Marrow Environment Impairs Hematopoietic Stem Cells by Exposure to Tumor Necrosis Factor a. (2010) (0)
- 3042 – CAS9-AAV6 GENE CORRECTION OF AUTOLOGOUS HSCS IMPROVES SICKLE CELL DISEASE ERYTHROPOIESIS IN MICE (2020) (0)
- Metalloproteinase Regulation Determines Integrin αIIbβ3 Function and Enhances the Capacity of ES Cell-Derived Platelets. (2006) (0)
- Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells (2016) (0)
- SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia (2020) (0)
- Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells (2016) (0)
- Haematopoietic stem cell self-renewal in vivo and ex vivo (2020) (0)
- Development and Regeneration of Hematopoietic Stem Cells (2016) (0)
- Large-scale in vivo CRISPR screens identify SAGA complex members as a key regulators of HSC lineage commitment and aging (2022) (0)
- MT1-MMP Plays a Critical Role In the Modulation of Hematopoiesis. (2010) (0)
- A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease (2017) (0)
- 31 PRODUCTION EFFICIENCY OF GENE KNOCKOUT PIGS USING GENOME EDITING AND SOMATIC CELL CLONING (2015) (0)
- Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells (2017) (0)
- 3202 – METABOLIC PROFILING OF MOUSE HEMATOPOIETIC STEM CELL SELF-RENEWAL AT SINGLE-CELL RESOLUTION (2022) (0)
- Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (0)
- 361: The Pharmacodynamic Analysis between Cyclosporine a (CsA) and Cytokine Profiles of CD4+ T Lymphocytes for the Development of Optimized Immunosuppressive Therapy with CsA after Unrelated Cord Blood Transplantation (CBT) (2008) (0)
- Identification of Fcδ/μ receptor expressed on B lymphocytes and macrophages (2001) (0)
- Mouse Full-Length cDNA Encyclopedia Targeting a Complex Transcriptome: The Construction of the (2006) (0)
- Author Correction: Investigation of Cas9 antibodies in the human eye (2022) (0)
- Large-Scale Clonal Analys is Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment Graphical (0)
- Cell Stem Cell Essential Role of Foxo 3 a in Self-Renewal of HSCs (0)
- Low Incidence of Cytomegalovirus Infection Associated with Rapid Cell-Mediated Immune Reconstitution after Cord Blood Transplantation Using Full Conditioning Regimen Containing 12Gy Total Body Irradiation. (2006) (0)
- Cytometry technologies for analysis of very small numbers of cells (LL2-5) Chairperson: Shigeo Koyasu (2010) (0)
- cells and interleukin-7 Support of early B-cell differentiation in mouse fetal liver by stromal (2011) (0)
- Running title : Generation of oocyte from xenogenic PGC (2014) (0)
- Branched-Chain Amino Acid Depletion Conditions Bone Marrow for HSCT Avoiding Amino Acid Imbalance-Associated Toxicity (2018) (0)
- Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system (2016) (0)
- Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance (2017) (0)
- [Technics of monoclonal antibody production with hybridomas and their medical application]. (1981) (0)
- Correction: A Comprehensive System for Generation and Evaluation of Induced Pluripotent Stem Cells Using piggyBac Transposition (2014) (0)
- 26 IN VIVO EXOGENIC ORGAN GENERATION WITH ORGANOGENESIS-DISABLED CLONED PIGS AS A PLATFORM (2014) (0)
- A Plasmin Inhibitor Prevents Lethal Acute Graft-Versus-Host Disease in Mice (2011) (0)
- A Chemical Approach for Ex Vivo Expansion of Human Hematopoietic Stem Cells (2011) (0)
- Title : Clock gene Bmal 1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2013) (0)
- Exploiting the Organ Niche for Interspecies Organogenesis (2018) (0)
- Cytokine-signal inhibitor Lnk upregulates integrin αIIbβ3 signaling in platelets (2006) (0)
- Hematopoietic stem cells (+iPS) (PP-010) (2010) (0)
- In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements (2011) (0)
- Development by Kinase-Inactive ZAP-70 Thymocyte - CD8 - Demonstrates Inhibition of CD4 An Improved Retroviral Gene Transfer Technique (2012) (0)
- Direct and Continuous Inhibition of ADAM17 Using a Novel Selective Inhibitor Restores Functional Platelet Yield From Human Pluripotent Stem Cells (2011) (0)
- [Recent progress in stem cell biology and its implications for future medicine]. (2008) (0)
- Organ transplantation (PP-076) (2010) (0)
- Differentiation of Mature Eosinophils From Human Embryonic and Induced Pluripotent Stem Cells. (2010) (0)
- Clonal Analysis of Progressive Maturation of Erythroid Cells from Human Embryonic Stem Cell-Derived Definitive Hematopoiesis. (2007) (0)
- PROSPECTIVE IDENTIFICATION AND PURIFICATION OF MULTI-POTENT HEPATIC STEM CELLS(Developmental Biology)Proceedings of the Seventy-First Annual Meeting of the Zoological Society of Japan (2000) (0)
- Megakaryocyte Lineage Commitment in Hematopoietic Stem Cells (2011) (0)
- colony formation and an inhibitory effect of IL-1 alpha A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B- cell (2011) (0)
- Molecular Cloning of Murine Lymphocyte Differentiation Antigen Ly- 1 and Its Predicted Structure (1986) (0)
- Long-term and multilineage bone marrow reconstitution in normal untreated recipients. (1996) (0)
- Expression and Characterization of Leucocyte Antigens (1984) (0)
- Molecular cloning ofLyt-2, amembraneglycoprotein marking a subset ofmouseTlymphocytes: Molecular homology toitshuman counterpart, Leu-2/T8, andtoimmunoglobulin variable regions (1985) (0)
- Use of cytokines for efficient introduction of foreign genes into the hematopoietic stem cell. (1994) (0)
- [Purification and characterization of the hematopoietic stem cell]. (2000) (0)
- Biological and genetic characterization of the role of SRSF2 mutations in the pathogenesis of myelodysplastic syndromes (2015) (0)
- A retrospective analysis of germline competence in rat embryonic stem cell lines (2012) (0)
- MT1-MMP Regulates Hematopoiesis Through HIF-Mediated Chemo-/Cytokine Release From the Bone Marrow Niche, (2011) (0)
- An optimized Sendai viral vector platform for reprogramming to naive pluripotency (2022) (0)
- human bone marrow Enrichment of interleukin-2-responsive natural killer progenitors in (2011) (0)
- Human hematopoietic stem/progenitor cells hibernate in vascular niche harboring GFAP-expressing cells (2013) (0)
- Clonal analysis in vivo unveils atypical dynamics of aged hematopoietic stem cells (2016) (0)
- Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML (2012) (0)
- Proof of Benefit in Multiple-Cord Blood Transplantation Evidenced By Early Hematopoietic Reconstitution (2015) (0)
- Transmission of lethal phenotype in a Mendelian fashion by genetically modified pigs that underwent blastocyst complementation (2014) (0)
- Negative Hematopoietic Scaffold Lnk Upregulates Integrin Outside-In Signaling in Platelets. (2005) (0)
- LAS Seminar 1 (2018) (0)
- Novel Functions for a Fibrinolytic Pathway in Controlling the Stem Cell Niche. (2006) (0)
- Méthode de production d'un animal chimère (2014) (0)
- Rapid Chimerism – Switch of Lymphocytes and Phenotypic Conversion of Naïve T Cells Early After Cord Blood Transplantation (2011) (0)
- Stem cells and regeneration medicine (2002) (0)
- Adaptor Protein Lnk Negatively Controls the Likelihood of Self-Renewal in Hematopoietic Stem Cells. (2006) (0)
- Kinase-Inactive ZAP-70 Thymocyte Development by - CD8 - Technique Demonstrates Inhibition of CD4 An Improved Retroviral Gene Transfer (1998) (0)
- The generation of functional organ by way of in utero transplantation (2017) (0)
- Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats (2019) (0)
- Generation of Tfap2c‐T2A‐tdTomato knock‐in reporter rats via adeno‐associated virus‐mediated efficient gene targeting (2022) (0)
- 324 PRODUCTION OF GENETICALLY MODIFIED PIGS BY ARTIFICIAL REPRODUCTIVE TECHNOLOGIES USING FROZEN EPIDIDYMAL SPERM (2013) (0)
- Dissecting the valine dependency of hematopoietic stem cell function (2017) (0)
- [Use of FACS for the isolation of stem cells]. (2003) (0)
- LASER-SCANNING FLOW CYTOMETER WITH A THREE-DIMENSIONAL MICROFLUIDIC CHIP (2008) (0)
- Conditions for the successful engraftment of hepatocyte progenitors injected into the spleen. (1996) (0)
- GENERATION OF FUNCTIONAL ORGANS FROM IPS CELLS: TOWARD THE NEXT GENERATION OF REGENERATIVE MEDICINE (INVITED SPEAKERS) (2011) (0)
- Simultaneous generation of vascular endothelial cells and hematopoietic cells from pluripotent stem cells by blastocyst complementation (2017) (0)
- Abstract 2894: Cardiac Mast Cells Cause Atrial Fibrillation Through PDGF-A-mediated Atrial Fibrosis in Pressure-overloaded Hearts (2009) (0)
- Identification of immature podocyte specific antigen using retrovirus-mediated gene transfer and cell sorting (2005) (0)
- Comprehensive Analysis of Surface Antigens on Adult T-Cell Leukemia/Lymphoma (ATL) Cells and Search for ATL-Initiating Cell Markers (2014) (0)
- Nucleic Acids Research Isolation and characterization of the gene for the marine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2 (2005) (0)
- Choice Between T and B Lymphocytes A Mouse Carrying Genetic Defect in the (0)
- [iPSC-derived rejuvenated T-cell therapy for Epstein-Barr virus-associated lymphomas]. (2018) (0)
- Physioxia improves the selectivity of hematopoietic stem cell expansion cultures. (2023) (0)
- Requirement forCD8P8 Chain inPositive Selection ofCD8-Lineage TCells (2016) (0)
- CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2017) (0)
- Epidermal Growth Factor-like Domain 7 Promotes Hematopoietic Stem Cell Expansion and Increases Myeloid-Megakaryocytic Lineage Priming through beta3 Integrin (2014) (0)
- Human iPSC Generation from Antigen-Specific T Cells. (2019) (0)
- Flow Cytometric Analysis of Donor-Recipient Chimerism Using Anti-HLA Antibody after HLA-Mismatched Cord Blood Transplantation. (2007) (0)
- Identification of CD34lo/−kit+sca+lin− cells in HOECHST33342 side population (Sp) Of the mouse bone marrow cells (2000) (0)
- An interspecies barrier to tetraploid complementation and chimera formation (2018) (0)
- Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin (2011) (0)
- Altered humoral immune reactivity in patients with chronic glomerulonephritis (1991) (0)
- Contribution of T-Cell Reconstitution during the Early Phase after Cord Blood Transplantation to Favorable Clinical Outcomes. (2004) (0)
- 255. Potent Cancer Immunotherapy with Dendritic Cells Generated from Genetically Modified Hematopoietic Stem Cells (2004) (0)
- Regenerative medicine for digestige organs and kidney (2013) (0)
- [Self-renewal potential of hematopoietic stem cells]. (2002) (0)
- Novel Therapeutic Approach To Graft-Versus-Host Disease With Allele-Specific Anti-HLA Monoclonal Antibody (2013) (0)
- Hemat opoietic Homeostasis against Diet-Induced Systemic Stress Graphical Abstract Highlights (2018) (0)
- Clock gene Bmal 1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2014) (0)
- In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects (2018) (0)
- 330. Genetic Modification of Murine Embryonic Stem Cells by the Gene Silencing Resistance Retroviral Vector GCDsap (2004) (0)
- Anephrogenic phenotype induced by SALL1 gene knockout in pigs (2019) (0)
- Identification of a novel cDNA clone encoding protein tyrosine kinase in murine skin. (1994) (0)
- Abstract of Public Open Special Lecture at Symposium (2005) (0)
- Myeloid Lineage Restriction Is Prior to and Independent of Lymphoid Lineage Restriction. (2006) (0)
- Bioluminescent Tracking of Human Induced Pluripotent Stem Cells In Vitro and In Vivo. (2022) (0)
- Integrin- (cid:1) v (cid:2) 3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells (2011) (0)
- Dietary created niche for non-myeloablative hematopoietic stem cell transplantation (2015) (0)
- Long-term ex vivo expansion of mouse hematopoietic stem cells (2020) (0)
- Efficient scarless genome editing in human pluripotent stem cells (2018) (0)
- Is donor-derived long-term and multilineage hematopoiesis established after liver transplantation? (1998) (0)
- Use of cytometry technology for the study of stem cell biology (2009) (0)
- In Vitro Myelo-Lymphoid Colony Formation by Mouse Hematopoietic Stem Cells (2008) (0)
- Control of self-renewal activity of hematopoietic stem cells by spred1 (2014) (0)
- A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells (2014) (0)
- Isolation and Characterization of CD34-Low/Negative Mouse Hematopoietic Stem Cells (2000) (0)
- Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2017) (0)
- Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep (2018) (0)
- Hematopoiesis Arises Independent of Vasculogenesis in the Early Mouse Embryos. (2006) (0)
- spreading machinery development and spreading: implications for platelet biogenesis and The WAVE2/Abi1 complex differentially regulates megakaryocyte (2013) (0)
- iPSC-derived Rejuvenated T-cell Therapy for Extranodal NK/T-cell Lymphoma, Nasal Type (2020) (0)
- LONG-TERM CULTURE OF FETAL LIVER CELLS USING THREE-DIMENSIONAL POROUS POLYMER (1999) (0)
- hematopoietic progenitors vitro via ES-sacs, VEGF-promoted structures that concentrate Generation of functional platelets from human embryonic stem cells in (2013) (0)
- Simple and efficient method of rat ICSI (2017) (0)
- Hematopoietic stem cells (+iPS) (WS-010) Chairpersons: Hiromitsu Nakauchi, Haruhiko Koseki (2010) (0)
- Prospective identification and enrichment of self-renewing multipotential hepatic stem cells by flow cytometric cell sorting (2001) (0)
- pluripotency Definitive proof for direct reprogramming of hematopoietic cells to (2009) (0)
- Proceedings of the 2nd Meeting of the Asian Cellular Therapy Organization (2011) (0)
- Results Cross-Circulatory System Is Stabilized 7 to 10 Days After Parabiotic Surgery (2015) (0)
- Molecular analysis of SJL and AKR lymphomas (1986) (0)
- In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells from Induced Pluripotent Stem Cells through Hemogenic Endothelium (2016) (0)
- The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer (2011) (0)
- Progress in Stem-Cell Research and New Medical Care (2014) (0)
- A New Strategy to Overcome the Cell Dose Barrier to Umbilical Cord Blood Transplants: A Proof of Early Hematopoietic Reconstitution By Combined Multiple Units of Allogeneic Stem/Progenitor Cells (2014) (0)
- Conversion of iPS derived hepatic progenitors into scalable, functional and developmentally relevant human organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold engineered from collagen-coated pores of defined size (2018) (0)
- Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2020) (0)
- Development of conditional hematopoietic cell abrogation system by CD45 promoter - Diphtheria Toxin Receptor (DTR) (2015) (0)
- [110th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: 1. Frontier of the regenerative medicine; 1) Regenerative medicine for digestive organs and kidney]. (2013) (0)
- Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (0)
- [Physiological and pathological roles of the truncated erythropoietin receptor]. (1997) (0)
- [Utilization of the ES/iPS cell technology for hematopoietic stem cell transplantation]. (2012) (0)
- Unique Gain-of-Function of Mutated c-CBL Tumor Suppresor in Myeloid Neoplasms. (2009) (0)
- Human Embryonic Stem Cell-Derived “NET-Like” Structure Serves as a Hematopoietic Progenitor Niche and Favors Generation of Mature Megakaryocytes and Functional Platelets. (2006) (0)
- Practice and technical barrier of intra-embryonic large cassette knock-in by Adeno-Associated Viral vector with Cas9 ribonucleoprotein electroporation. (2019) (0)
- Homeostatic regulation of hematopoietic stem cells by the interaction of niche factors (2015) (0)
- Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors (2017) (0)
- LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells (2019) (0)
- Protection of Transplanted Hematopoietic Stem Cells from Inflammatory Recipient Marrow Environment through Specific TNF-α Signal Blockade (2015) (0)
- HSC-independent lymphopoiesis (HEM1P.228) (2015) (0)
- Detection of lineage-specific STAT5A phosphorylation in peripheral blood cells from a myeloproliferative neoplasm model mouse using multicolor flow cytometry (2010) (0)
- Analysis of Lymphocyte Subsets in Human Diseases (1983) (0)
- 2001 - LONG-TERM EX VIVO EXPANSION OF FUNCTIONAL HEMATOPOIETIC STEM CELLS (2019) (0)
- Role of spred1 in the regulation of self-renewal and aging of hematopoietic stem cells (2015) (0)
- A new gene transfer system for hematopoietic stem cells under physiological condition (2015) (0)
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What Schools Are Affiliated With Hiromitsu Nakauchi?
Hiromitsu Nakauchi is affiliated with the following schools: