Hiromitsu Nakauchi

Hiromitsu Nakauchi's AcademicInfluence.com Rankings

Hiromitsu Nakauchi

Biology

#6334

World Rank

#9024

Historical Rank

Biotechnology

#57

World Rank

#58

Historical Rank

Molecular Biology

#640

World Rank

#655

Historical Rank

Genetics

#585

World Rank

#665

Historical Rank

biology Degrees

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Biology

Hiromitsu Nakauchi's Degrees

PhD Biology Stanford University
Masters Biotechnology University of Tokyo
Bachelors Biochemistry University of Tokyo

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Hiromitsu Nakauchi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Transcriptional Landscape of the Mammalian Genome (2005) (3394)
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype (2001) (2338)
Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell (1996) (1929)
Frequent pathway mutations of splicing machinery in myelodysplasia (2011) (1799)
Expression and function of c-kit in hemopoietic progenitor cells (1991) (764)
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche (2011) (695)
Age-Associated Characteristics of Murine Hematopoietic Stem Cells (2000) (679)
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell–like properties (2006) (675)
Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells (2013) (568)
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. (2004) (557)
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. (1992) (538)
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. (1995) (525)
Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells (2010) (486)
Foxo3a is essential for maintenance of the hematopoietic stem cell pool. (2007) (437)
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation (2006) (429)
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms (2009) (415)
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment (2010) (404)
Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver (2002) (353)
Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. (2015) (340)
Development of Defective and Persistent Sendai Virus Vector (2010) (328)
Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. (2000) (327)
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms (2012) (325)
In Vitro Self-Renewal Division of Hematopoietic Stem Cells (2000) (322)
Presence of hematopoietic stem cells in the adult liver (1996) (318)
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. (2013) (305)
TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. (2009) (301)
Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival. (1991) (299)
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells (2010) (298)
Flow‐cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver (2000) (288)
Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. (2008) (284)
Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells. (2014) (276)
Fcα/μ receptor mediates endocytosis of IgM-coated microbes (2000) (275)
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells (2006) (270)
Hoxb5 marks long-term haematopoietic stem cells revealing a homogenous perivascular niche (2016) (254)
Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation (1993) (244)
Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting. (2004) (242)
Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. (1999) (240)
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice (2004) (232)
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice (2006) (231)
New ISSCR guidelines underscore major principles for responsible translational stem cell research. (2008) (230)
CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation (2003) (229)
Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs (2013) (228)
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. (1991) (226)
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells (2007) (218)
Generation of osteoclasts from isolated hematopoietic progenitor cells. (1989) (218)
Interspecies organogenesis generates autologous functional islets (2017) (216)
A Role for Pref-1 and HES-1 in Thymocyte Development (2000) (216)
Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. (2005) (215)
Essential and Instructive Roles of GATA Factors in Eosinophil Development (2002) (206)
Hair follicle stem cells provide a functional niche for melanocyte stem cells. (2011) (203)
Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation. (2007) (202)
The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. (2008) (201)
Adult mouse hematopoietic stem cells: purification and single-cell assays (2006) (197)
The dose dependence of glucocorticoid‐inducible gene expression results from changes in the number of transcriptionally active templates. (1990) (197)
Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex* (1998) (196)
Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer (1998) (195)
Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls (1999) (193)
A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage (2012) (193)
Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis (2005) (190)
Sal‐like protein 4 (SALL4), a stem cell biomarker in liver cancers (2013) (190)
Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. (2013) (186)
Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1. (2010) (184)
Generation of kidney from pluripotent stem cells via blastocyst complementation. (2012) (183)
Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells (2003) (180)
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule (1991) (179)
Establishment of mouse expanded potential stem cells (2017) (178)
Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. (2003) (176)
Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis (2008) (175)
Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton’s jelly explants of human umbilical cord (2009) (168)
In vivo self-renewal of c-Kit+ Sca-1+ Lin(low/-) hemopoietic stem cells. (1996) (167)
Flow cytometric isolation and clonal identification of self‐renewing bipotent hepatic progenitor cells in adult mouse liver (2008) (166)
A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells (1992) (161)
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. (2003) (159)
Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts. (2010) (157)
Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction (2007) (155)
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. (2006) (153)
Long-term ex vivo hematopoietic stem cell expansion affords nonconditioned transplantation (2019) (151)
A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage (2014) (147)
Human primitive hematopoietic progenitor cells are more enriched in KITlow cells than in KIThigh cells. (1993) (147)
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. (2010) (145)
Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. (2008) (139)
Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis. (2002) (139)
Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. (2000) (137)
Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells. (1992) (129)
Colony formation of clone-sorted human hematopoietic progenitors. (1990) (128)
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation (2016) (128)
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells. (1994) (127)
Stem cells and interspecies chimaeras (2016) (126)
Glucagon-like peptide 1 (1–37) converts intestinal epithelial cells into insulin-producing cells (2003) (126)
Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. (2007) (118)
Musculin/MyoR is expressed in kidney side population cells and can regulate their function (2005) (116)
Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment (2002) (115)
A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non‐hematopoietic tissues (2001) (114)
Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia (2004) (113)
Paired Activating and Inhibitory Immunoglobulin-like Receptors, MAIR-I and MAIR-II, Regulate Mast Cell and Macrophage Activation (2003) (113)
Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease (2014) (109)
Developmental Epigenetic Modification Regulates Stochastic Expression of Clustered Protocadherin Genes, Generating Single Neuron Diversity (2014) (109)
Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. (2009) (108)
Asymmetric Division and Lineage Commitment at the Level of Hematopoietic Stem Cells (2004) (108)
Microchimerism in Japanese women patients with systemic sclerosis (1999) (103)
Revisiting the flight of Icarus: making human organs from PSCs with large animal chimeras. (2014) (103)
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment (2018) (102)
Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice. (2009) (99)
Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. (1997) (97)
The Sox-2 Regulatory Regions Display Their Activities in Two Distinct Types of Multipotent Stem Cells (2004) (96)
Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes. (2013) (94)
Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells (2012) (93)
Lymphokine requirement for the generation of natural killer cells from CD34+ hematopoietic progenitor cells. (1995) (93)
CD226 Mediates Platelet and Megakaryocytic Cell Adhesion to Vascular Endothelial Cells* (2003) (93)
Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils. (1990) (91)
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. (2019) (90)
Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives (2017) (89)
Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. (2016) (88)
Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions (2014) (87)
Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. (1985) (86)
Functional characterization of hematopoietic stem cells in the spleen. (2011) (85)
Role of SOX17 in hematopoietic development from human embryonic stem cells. (2013) (85)
Interleukin-27 directly induces differentiation in hematopoietic stem cells. (2008) (85)
Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. (2010) (84)
Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo (2020) (83)
In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling. (2012) (82)
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021) (82)
Comparison of Hematopoietic Activities of Human Bone Marrow and Umbilical Cord Blood CD34 Positive and Negative Cells (1999) (82)
Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development (2005) (81)
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. (2009) (80)
Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold (2018) (75)
Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls. (1999) (75)
A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. (1989) (75)
Do Pluripotent Stem Cells Exist in Adult Mice as Very Small Embryonic Stem Cells? (2013) (75)
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats (2019) (75)
Haematopoietic stem cell self-renewal in vivo and ex vivo (2020) (74)
Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver. (2000) (73)
In vivo analysis of Fas antigen-mediated apoptosis: effects of agonistic anti-mouse Fas mAb on thymus, spleen and liver. (1997) (73)
Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors (2019) (72)
Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf‐dependent and ‐independent manners in Mice (2010) (72)
Generation of Germline-Competent Rat Induced Pluripotent Stem Cells (2011) (72)
Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. (2010) (71)
Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone. (1985) (71)
An In Vitro Expansion System for Generation of Human iPS Cell-Derived Hepatic Progenitor-Like Cells Exhibiting a Bipotent Differentiation Potential (2013) (71)
Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients (2014) (69)
Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells (2013) (69)
Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells. (1996) (69)
Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells (2008) (69)
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration. (2007) (69)
Non-side-population hematopoietic stem cells in mouse bone marrow. (2006) (67)
The Proportion of Fetal Nucleated Red Blood Cells in Maternal Blood: Stimation by FACS Analysis (1997) (67)
Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. (2018) (67)
Evidence for Hepatocyte Differentiation from Embryonic Stem Cells In Vitro (2002) (66)
Targeted organ generation using Mixl1-inducible mouse pluripotent stem cells in blastocyst complementation. (2015) (66)
IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect. (1993) (66)
Two alternative forms of cDNA encoding CD34. (1993) (64)
Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma (2010) (63)
Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling. (2013) (62)
Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules. (1992) (61)
A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy (2015) (61)
Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing. (2007) (60)
Analyses of cell surface molecules on hepatic stem/progenitor cells in mouse fetal liver. (2009) (60)
Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells. (2012) (60)
Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice. (1996) (59)
Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder- and Serum-Free Defined Conditions (2010) (57)
Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase (2011) (56)
Identification of rat Rosa26 locus enables generation of knock-in rat lines ubiquitously expressing tdTomato. (2012) (56)
Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes. (2016) (56)
A melanocyte–melanoma precursor niche in sweat glands of volar skin (2014) (56)
Il-7 supports D-J but not V-DJ rearrangement of TCR-beta gene in fetal liver progenitor cells. (1996) (56)
The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells (2013) (56)
Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product, Bmi-1. (2004) (55)
Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice. (2018) (55)
Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma (2010) (55)
Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease (2009) (54)
Putative “Stemness” Gene Jam-B Is Not Required for Maintenance of Stem Cell State in Embryonic, Neural, or Hematopoietic Stem Cells (2006) (54)
Prospero‐related homeobox 1 and liver receptor homolog 1 coordinately regulate long‐term proliferation of murine fetal hepatoblasts (2008) (54)
Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells (2015) (53)
Stepwise Development of Hematopoietic Stem Cells from Embryonic Stem Cells (2009) (53)
Successful multilineage engraftment of human cord blood cells in pigs after in utero transplantation (2003) (53)
Mac-1(low) early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration. (2004) (53)
Further Characterization of CD34‐Low/Negative Mouse Hematopoietic Stem Cells (1999) (52)
Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury (2015) (52)
Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice. (2012) (52)
Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells. (2002) (52)
Beta-chain broadens range of CD8 recognition for MHC class I molecule. (1992) (51)
Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes (2011) (51)
Cell cycle dependence of boron uptake from two boron compounds used for clinical neutron capture therapy. (2002) (50)
Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment (2015) (49)
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells (2019) (49)
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2017) (48)
Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo (2006) (48)
The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery. (2007) (48)
Quantitative Assessment of the Stem Cell Self‐Renewal Capacity (2001) (48)
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells. (2012) (48)
Induction of M-phase arrest and apoptosis after HIV-1 Vpr expression through uncoupling of nuclear and centrosomal cycle in HeLa cells. (2000) (47)
Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation (2018) (47)
Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells (2015) (46)
Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation (2015) (46)
A truncated erythropoietin receptor and cell death: a reanalysis. (1994) (46)
Definitive proof for direct reprogramming of hematopoietic cells to pluripotency. (2009) (45)
Reconstitution ratio is critical for alloreactive T cell deletion and skin graft survival in mixed bone marrow chimeras. (1995) (45)
Epigenetic Regulation of Hematopoietic Stem Cell Self-Renewal by Polycomb Group Genes (2005) (45)
Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia (2014) (44)
Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals. (2008) (44)
Homeodomain Transcription Factor Meis1 Is a Critical Regulator of Adult Bone Marrow Hematopoiesis (2014) (43)
Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL. (2009) (43)
Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice. (2001) (42)
Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells (2014) (42)
Hematopoietic stem cells: Are they CD34-positive or CD34-negative? (1998) (41)
Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. (1986) (40)
Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector (2018) (40)
Inhibition of plasmin protects against colitis in mice by suppressing matrix metalloproteinase 9-mediated cytokine release from myeloid cells. (2015) (40)
Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus (2016) (40)
Changes in hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblasts during differentiation. (1993) (40)
B220 expression by T lymphoid progenitor cells in mouse fetal liver. (1997) (40)
Long-term ex vivo expansion of mouse hematopoietic stem cells (2020) (39)
Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells. (2000) (39)
A chemical probe that labels human pluripotent stem cells. (2014) (39)
Establishment of rat embryonic stem cell lines that can participate in germline chimerae at high efficiency (2010) (39)
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice. (2011) (39)
Identification and differentiation of hepatic stem cells during liver development. (2006) (38)
Cytokine Signaling, Lipid Raft Clustering, and HSC Hibernation (2007) (38)
Support of early B-cell differentiation in mouse fetal liver by stromal cells and interleukin-7. (1991) (38)
Fcα/µ receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1 (2001) (38)
Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity. (2017) (38)
Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells (2012) (38)
Stem cell therapy: an exercise in patience and prudence (2013) (37)
Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions. (1987) (36)
Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice (2020) (36)
Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin (2014) (36)
Stage‐Specific Roles for Cxcr4 Signaling in Murine Hematopoietic Stem/Progenitor Cells in the Process of Bone Marrow Repopulation (2014) (35)
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. (2016) (35)
Sequential analysis of hematopoietic reconstitution achieved by transplantation of hematopoietic stem cells. (1993) (35)
Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation (2019) (35)
Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells. (2015) (35)
Potent vaccine therapy with dendritic cells genetically modified by the gene-silencing-resistant retroviral vector GCDNsap. (2006) (35)
Generation of Recombination Activating Gene-1-Deficient Neonatal Piglets: A Model of T and B Cell Deficient Severe Combined Immune Deficiency (2014) (34)
Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome. (2017) (34)
Detection of fetal HPCs in maternal circulation after delivery (2001) (33)
T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera. (2009) (33)
A mouse carrying genetic defect in the choice between T and B lymphocytes. (1998) (33)
Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. (1992) (33)
Development of an All-in-One Inducible Lentiviral Vector for Gene Specific Analysis of Reprogramming (2012) (33)
Changing concepts in hematopoietic stem cells (2018) (32)
Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking (2014) (32)
Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. (2009) (32)
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors (2017) (32)
Deregulated Intracellular Signaling by Mutated c-CBL in Myeloid Neoplasms (2010) (32)
Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins (2016) (31)
Rat transgenesis via embryonic stem cells electroporated with the Kusabira‐orange gene (2010) (31)
Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes (2019) (30)
Liver repopulation by c-Met-positive stem/progenitor cells isolated from the developing rat liver. (2004) (30)
Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation (2016) (30)
Novel strategies for liver therapy using stem cells (2014) (29)
The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer (2012) (29)
Long-Term Culture of Fetal Liver Cells Using a Three-Dimensional Porous Polymer Substrate (2000) (29)
Molecular evidence that SJL reticulum cell sarcomas are derived from pre-B cell. Clonal rearrangement of heavy chain but not of light chain immunoglobulin genes. (1987) (28)
Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies (2014) (28)
Prospective isolation and characterization of bipotent progenitor cells in early mouse liver development. (2012) (28)
Somatic Gene Therapy for Diabetes With an Immunological Safety System for Complete Removal of Transplanted Cells (1992) (28)
Self-renewal and lineage restriction of hematopoietic stem cells. (2003) (27)
TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Commentary (2009) (27)
An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70. (1998) (26)
iPSC-Derived Organs In Vivo: Challenges and Promise. (2018) (26)
In Vitro Production of Functionally Mature Hepatocytes from Prospectively Isolated Hepatic Stem Cells (2003) (26)
CD 226 ( DNAM-1 ) Is Involved in Lymphocyte Function – associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation (2003) (26)
The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs. (2014) (26)
Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b+/F4/80+ myeloid cell recruitment (2012) (26)
Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns (2013) (26)
Interspecies chimeras. (2018) (25)
In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma (2017) (25)
Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3 (2014) (25)
A Comprehensive System for Generation and Evaluation of Induced Pluripotent Stem Cells Using piggyBac Transposition (2014) (25)
The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells. (2011) (25)
Insights into signaling and function of hematopoietic stem cells at the single-cell level (2009) (24)
Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds (2019) (24)
Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. (2005) (24)
Establishment of Clonal Colony-Forming Assay System for Pancreatic Stem/Progenitor Cells (2002) (24)
Binding of c-Myb to the core sequence of the CD4 promoter. (1993) (24)
Recent duplication of the two human CD8 beta-chain genes. (1992) (24)
Effects of interleukin 3, interleukin 6, and granulocyte colony-stimulating factor on sorted murine splenic progenitor cells. (1991) (24)
CD4dull+ hematopoietic progenitor cells in murine bone marrow (1993) (23)
Synergistic effect of IL-3 and IL-6 on highly enriched murine hemopoietic progenitors. (1992) (23)
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress. (2018) (23)
Plenary Lecture (2017) (23)
Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells (2013) (23)
Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity (2018) (22)
Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11. (1988) (22)
T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung. (2015) (22)
Full reconstitution of hematopoietic system by murine umbilical cord blood (2003) (22)
Lessons from Interspecies Mammalian Chimeras. (2017) (22)
Generation of Col2a1-EGFP iPS Cells for Monitoring Chondrogenic Differentiation (2013) (22)
Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow (1993) (22)
Establishment and functional analysis of a cloned, antigen-specific suppressor effector T cell line. (1984) (22)
Characterization of the ICSI‐mediated gene transfer method in the production of transgenic pigs (2012) (21)
Pre‐Transplantation Blockade of TNF‐α‐Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells (2017) (21)
Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera. (2011) (21)
Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells. (2012) (21)
Interspecies chimeras for human stem cell research (2017) (21)
Comparative structure of two duplicated T1a class I genes (T10c and 37) of the murine H-2d MHC. Implications on the evolution of the T1a region. (1990) (21)
Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. (2013) (21)
A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells (2008) (21)
Efficient scarless genome editing in human pluripotent stem cells (2018) (21)
Role of c-jun in the inhibition of erythropoietin receptor-mediated apoptosis. (1996) (21)
Bone marrow Schwann cells induce hematopoietic stem cell hibernation (2014) (20)
In vivo haematopoietic potential of human neural stem cells (2005) (20)
Treatment of a genetic brain disease by CNS-wide microglia replacement (2022) (20)
Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts (2014) (20)
An interspecies barrier to tetraploid complementation and chimera formation (2018) (20)
Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1 (2015) (20)
Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras. (2020) (20)
Identification and propagation of liver stem cells. (2002) (20)
Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep (2018) (20)
Parvovirus Nonstructural Proteins Induce an Epigenetic Modification through Histone Acetylation in Host Genes and Revert Tumor Malignancy to Benignancy (2005) (20)
Lift NIH restrictions on chimera research. (2015) (19)
In vivo stem cell function of interleukin-3-induced blast cells. (1991) (19)
Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. (1987) (19)
The Actin Polymerization Regulator WAVE2 Is Required for Early Bone Marrow Repopulation by Hematopoietic Stem Cells (2009) (19)
'Off-the-shelf' immunotherapy with iPSC-derived rejuvenated cytotoxic T lymphocytes. (2017) (19)
Thy-1 as a negative growth regulator in ras-transformed mouse fibroblasts. (1991) (19)
Cyclosporin A inhibits the decrease of CD4/CD8 expression induced by protein kinase C activation. (1993) (18)
Human immunodeficiency virus type 2 envelope glycoprotein binds to CD8 as well as to CD4 molecules on human T cells (1997) (18)
Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples. (2014) (18)
Reprogramming adult hematopoietic cells (2010) (18)
Modeling lethal X-linked genetic disorders in pigs with ensured fertility (2018) (18)
Increased cell surface expression of C‐terminal truncated erythropoietin receptors in polycythemia (2001) (18)
CD4 and CD8 regulate interleukin 2 responses of T cells. (1992) (18)
Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats (2021) (17)
Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain. (2006) (17)
Constant delivery of proinsulin by encapsulation of transfected cells. (1997) (17)
Gene Targeting Study Reveals Unexpected Expression of Brain-expressed X-linked 2 in Endocrine and Tissue Stem/Progenitor Cells in Mice* (2014) (17)
"Homing to Niche," a new criterion for hematopoietic stem cells? (2004) (17)
Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2017) (17)
Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth. (2015) (17)
Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells (2014) (17)
Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells (2012) (16)
Different effects of substitutions at residues 224 and 228 of MHC class I on the recognition of CD8. (1993) (16)
Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice (2013) (16)
Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments. (1989) (16)
Evidence for the presence of hematopoietic stem cells in the adult liver. (1995) (16)
Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (16)
Enzyme augmentation therapy enhances the therapeutic efficacy of bone marrow transplantation in mucopolysaccharidosis type II mice. (2014) (16)
Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells (1997) (15)
A retrospective analysis of germline competence in rat embryonic stem cell lines (2013) (15)
Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow. (1993) (15)
Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cells. (2016) (15)
Fc(alpha)/mu receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1. (2001) (15)
A quantitative analysis of cell surface glycosphingolipid with a fluorescence activated cell sorter. (1983) (15)
Transgenic Pigs with Pancreas-specific Expression of Green Fluorescent Protein (2014) (15)
Usefulness of flow-cytometric cell sorting for enrichment of hepatic stem and progenitor cells in the liver. (2000) (15)
Bone marrow chimerism prevents atherosclerosis in arterial walls of mice deficient in apolipoprotein E. (2002) (15)
Generation of Mouse Functional Oocytes in Rat by Xeno-Ectopic Transplantation of Primordial Germ Cells1 (2014) (14)
A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease (2017) (14)
Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. (2017) (14)
CD4dull+ hematopoietic progenitor cells in murine bone marrow. (1993) (14)
FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells. (2010) (14)
Non-myeloablative preconditioning with ACK2 (anti-c-kit antibody) is efficient in bone marrow transplantation for murine models of mucopolysaccharidosis type II. (2016) (14)
Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL. (2012) (14)
LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells (2019) (14)
Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83. (2000) (14)
Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system (2016) (13)
High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis (2021) (13)
CD3‐induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor (1996) (13)
The basic helix-loop-helix transcription factor, Mist1, induces maturation of mouse fetal hepatoblasts (2015) (13)
Characterization of the mouse interleukin-13 receptor α1 gene (2000) (13)
A Comparison of the Rest Complex Binding Patterns in Embryonic Stem Cells and Epiblast Stem Cells (2014) (13)
Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells. (2021) (13)
Stabilizing hematopoietic stem cells in vitro. (2020) (13)
Rapid T‐cell chimerism switch and memory T‐cell expansion are associated with pre‐engraftment immune reaction early after cord blood transplantation (2013) (13)
Isolation and Clonal Characterization of Hematopoietic and Liver Stem Cells (2004) (13)
Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms (2010) (12)
New Type of Matrix Support for Bone Marrow Cell Cultures:In Vitro Culture and In Vivo Transplantation Experiments (2000) (12)
Application of Droplet Digital PCR for Estimating Vector Copy Number States in Stem Cell Gene Therapy (2016) (12)
Analyses of adult T-cell leukemia using the monoclonal (anti-Leu-1, anti-Leu-2a, and anti-Leu-3a) and heterologous anti-glycolipid (anti-asialo GM1) antibodies. (1982) (12)
Impaired erythropoiesis in transgenic mice overexpressing a truncated erythropoietin receptor. (1998) (12)
Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease (2014) (12)
Treatment of diabetic mice with encapsulated fibroblasts producing human proinsulin. (1992) (12)
An improved method to make sequential deletion mutants for DNA sequencing. (1989) (12)
Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA (2018) (12)
An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2 (2008) (12)
The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells (2014) (12)
Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method (2017) (12)
Generation of B lymphocytes from a single hemopoietic progenitor cell in vitro. (1991) (12)
Ability of tetraploid rat blastocysts to support fetal development after complementation with embryonic stem cells (2012) (12)
CD 226 Mediates Platelet and Megakaryocytic Cell Adhesion to Vascular Endothelial Cells * (2003) (11)
In vitro expansion and functional recovery of mature hepatocytes from mouse adult liver (2012) (11)
Fractalkine shares signal sequence with TARC: gene structures and expression profiles of two chemokine genes. (2001) (11)
Characterization of an antigen-specific suppressive factor derived from a cloned suppressor effector T cell line. (1984) (11)
Recipient-derived cells after cord blood transplantation: dynamics elucidated by multicolor FACS, reflecting graft failure and relapse. (2008) (11)
Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species (2021) (11)
Control of cell growth and differentiation during early B-cell development by stromal cell molecules. (1989) (11)
Role of a truncated erythropoietin receptor for erythroid differentiation. (1996) (11)
Stable transgene expression in mice generated from retrovirally transduced embryonic stem cells. (2007) (11)
Antigen recognition by the T cell receptor is enhanced by CD8 α-chain binding to the α3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8α (1992) (11)
Glycosphingolipids of rat T cells. Predominance of asialo-GM1 and GD1c. (1994) (11)
Diff erential impact of Ink 4 a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi 1-defi cient mice (2006) (11)
Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. (2019) (11)
Clonal Expansion of Hepatic Stem/Progenitor Cells following Flow Cytometric Cell Sorting (2001) (10)
Hedgehog Activation Regulates Human Osteoblastogenesis (2020) (10)
Germline development in rat revealed by visualization and deletion of Prdm14 (2020) (10)
Use of cell type‐specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development (2014) (10)
Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers (2020) (10)
Sustainable Tumor-Suppressive Effect of iPSC-Derived Rejuvenated T Cells Targeting Cervical Cancers (2020) (10)
Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo (2019) (10)
MEK-ERK Activity Regulates the Proliferative Activity of Fetal Hepatoblasts Through Accumulation of p16/19(cdkn2a). (2015) (10)
Isolation of Murine Hematopoietic Stem Cells and Progenitor Cells (2005) (10)
Unique composition of polycomb repressive complex 1 in hematopoietic stem cells (2007) (10)
Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing (2009) (10)
Engraftment of human myelodysplastic syndrome derived cell line in transgenic severe combined immunodeficient (TG‐SCID) mice expressing human GM–CSF and IL‐3 (1998) (10)
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (10)
Molecular cloning and characterization of mouse Tspan-3, a novel member of the tetraspanin superfamily, expressed on resting dendritic cells. (2001) (10)
Multicolor Flow‐Cytometric, Morphologic, and Clonogenic Analysis of Marrow CD10‐Positive Cells in Children With Leukemia in Remission or Nonmalignant Diseases (1998) (9)
Prolonged survival of dog kidney allografts induced by a monoclonal anti-Ia antibody. (1984) (9)
Mouse immunoglobulin allotypes: multiple differences between the nucleic acid sequences of the IgEaand IgEballeles (2004) (9)
ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts (2021) (9)
New type of matrix support for bone marrow cell cultures: in vitro culture and in vivo transplantation experiments. (1999) (9)
Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. (2019) (9)
Immunoglobulin levels in patients on long-term hemodialysis. (1981) (9)
Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2014) (9)
Chimeric liver transplantation reveals interspecific graft remodelling. (2018) (9)
Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. (2019) (9)
Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications (2018) (9)
Isolation of a cDNA encoding a tyrosine kinase expressed in murine skin (1997) (9)
Practical selection methods for rat and mouse round spermatids without DNA staining by flow cytometric cell sorting (2016) (9)
Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis. (2012) (9)
Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6 (2018) (8)
Polycomb gene product Bmi-1 regulates stem cell self-renewal. (2005) (8)
Single-cell analysis of mitochondrial DNA in patients and a carrier of the tRNALeu(UUR) gene mutation (1999) (8)
Clonogenic Colony-Forming Ability of Flow Cytometrically Isolated Hepatic Progenitor Cells in the Murine Fetal Liver (2000) (8)
Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. (2014) (8)
Functional primordial germ cell–like cells from pluripotent stem cells in rats (2022) (8)
Clonal colony formation of hepatic stem/progenitor cells enhanced by embryonic fibroblast conditioning medium. (2000) (8)
DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells (2014) (8)
Evidence for the presence of hepatic stem cells in the murine fetal liver. (1999) (8)
The generation and maintenance of rat induced pluripotent stem cells. (2014) (8)
Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts (2019) (8)
Cloning of Homozygous a1,3-Galactosyltransferase Gene Knock-Out Pigs by Somatic Cell Nuclear Transfer (2012) (8)
Duplication of the CD8 beta-chain gene as a marker of the man-gorilla-chimpanzee clade. (1993) (7)
A novel stromal cell-dependent B lymphoid stem-like cell line that induces immunoglobulin gene rearrangement. (1999) (7)
Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease (2011) (7)
Loss of ganciclovir sensitivity by exclusion of thymidine kinase gene from transplanted proinsulin-producing fibroblasts as a gene therapy model for diabetes. (1996) (7)
Effect of donor chimerism to reduce the level of glycosaminoglycans following bone marrow transplantation in a murine model of mucopolysaccharidosis type II (2015) (7)
Investigation of Cas9 antibodies in the human eye (2022) (7)
Restricting Elements in the Immunological Circuitry: the Role of I Region‐Controlled Determinants (1983) (7)
Hepatic stem/progenitor cells with high proliferative potential in liver organ formation. (2001) (7)
T-cell subsets in patients with gastric cancer. (1985) (7)
Differential Level in Co‐Down‐Modulation of CD4 and CXCR4 Primed by HIV‐1 gp120 in Response to Phorbol Ester, PMA, among HIV‐1 Isolates (2000) (7)
Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. (2016) (7)
An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils (2015) (7)
Evidence for the existence of two parallel differentiation pathways in the thymus of MRL lpr/lpr mice. (1992) (7)
Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses (2022) (7)
Effective treatment against severe graft-versus-host disease with allele-specific anti-HLA monoclonal antibody in a humanized mouse model. (2015) (7)
Anephrogenic phenotype induced by SALL1 gene knockout in pigs (2019) (7)
Designing Motif-Engineered Receptors To Elucidate Signaling Molecules Important for Proliferation of Hematopoietic Stem Cells. (2018) (7)
Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells (2017) (7)
Structure and expression of the gene encoding CD8α chain (Leu-2/T8) (1989) (6)
Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells. (2015) (6)
Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (6)
Clonal deletion of thymic mature T cells induced by staphylococcal enterotoxin B in murine fetal thymus organ culture (1993) (6)
Chemically defined cytokine-free expansion of human haematopoietic stem cells (2023) (6)
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (6)
Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo (2021) (6)
Antigen recognition by the T cell receptor is enhanced by CD8 alpha-chain binding to the alpha 3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8 alpha. (1992) (6)
Xenotransplantation and interspecies organogenesis: current status and issues (2022) (6)
Effects of combined growth factors on clonal growth and albumin secretion of murine fetal hepatocytes in low density culture. (2000) (6)
Clonogenic colony-forming ability of flow cytometrically isolated hepatic progenitor cells in the murine fetal liver. (2000) (6)
Proliferative and functional ability of transplanted murine neonatal hepatocytes in adult livers. (2000) (6)
MHC gene Q8/9d of the BALB/cJ mouse strain cannot encode a Qa-2,3 class I antigen (2004) (5)
Principles of Hematopoietic Stem Cell Biology (2010) (5)
Early B Cell Differentiation from Hematopoietic Stem Cells in the Presence of Stromal Cells and Interleukin-7 (IL-7) (1990) (5)
Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma. (2021) (5)
Immunological barriers to haematopoietic stem cell gene therapy (2022) (5)
In vivo hematopoietic potential of human neuronal stem cells (2000) (5)
Knock‐in of a histone H2B‐tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats (2015) (5)
Germline development in rat revealed by visualization and deletion of Prdm14. (2020) (5)
Identification and characterization of in vitro expanded hematopoietic stem cells (2022) (5)
Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation (2016) (5)
Hematopoietic Stem Cells in the Mouse Spleen (2008) (5)
Multipotent and Committed CD34+ Cells in Bone Marrow Transplantation (1991) (5)
An in vivo assay for retrovirally transduced human peripheral T lymphocytes using nonobese diabetic/severe combined immunodeficiency mice. (2005) (5)
Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells. (2013) (5)
The distinct subgroup of patients with rheumatoid arthritis shown by Ig G3-reactive rheumatoid factor. (1989) (5)
Dominant expansion of human T cells in non-obese diabetic/severe combined immunodeficiency mice implanted with human bone fragments. (2000) (5)
Cross-species blastocyst chimerism between nonhuman primates using iPSCs (2019) (5)
Control of proinsulin production by sense-anti-sense regulation in response to glucocorticoids. (1996) (5)
Molecular cloning, reconstruction and expression of the gene encoding the alpha-chain of the bovine CD8--definition of three peptide regions conserved across species. (1992) (4)
Quantification of adult T-cell leukemia/lymphoma cells using simple four-color flow cytometry (2015) (4)
iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma (2021) (4)
Single amino acid substitution in the V3 domain of CD4 is responsible for OKT4 epitope deficiency (2004) (4)
Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors (2017) (4)
Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells (2011) (4)
Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation (2022) (4)
Effects of four extracellular matrices associated with growth factors on clonal culture and proliferation of murine fetal hepatocytes. (2000) (4)
Expression of Leu M1 antigen on a monoclonal B cell line established from a patient with rheumatoid arthritis. (1989) (4)
Advances in Allogeneic Cancer Cell Therapy and Future Perspectives on “Off-the-Shelf” T Cell Therapy Using iPSC Technology and Gene Editing (2022) (4)
Specific amino acid environments of bone marrow are crucial for the maintenance of hematopoietic stem cells (2015) (4)
Characterization of hematopoietic stem cells in the adult liver. (1997) (4)
Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts (2017) (4)
Extent of chimerism determines the mode of tolerance in mixed bone marrow chimeras. (1997) (4)
1107. Gene Therapy Clinical Trials for Relapsed Leukemia with Infusions of the Suicide-Gene Transduced Donor Lymphocytes in Japan (2006) (4)
Expression and function of the transfected CD8 alpha chain in murine T cell hybridomas. (1990) (3)
Rat Blastocysts from Nuclear Injection and Time-Lagged Enucleation and Their Commitment to Embryonic Stem Cells. (2016) (3)
Investigation of bipotent differentiation of hepatoblasts using inducible diphtheria toxin receptor‐transgenic mice (2016) (3)
The role of peripheral blood T and B lymphocytes in mitogen responses during human pregnancy. (1985) (3)
Enrichment and clonal culture of hepatic stem/progenitor cells during mouse liver development. (2013) (3)
A human cell line of chronic myelogenous leukemia releasing a novel virus-like particle. (1988) (3)
Five-lineage clonal analysis of hematopoietic stem/progenitor cells. (2014) (3)
Abstract 5119: Frequent splicing pathway mutations and aberrant RNA splicing in myelodysplasia (2012) (3)
Autosomal codominant inheritance and Japanese incidence of deficiency of OKT4 epitope with lack of reactivity resulting from conformational change. (1993) (3)
[From cell therapy to organ regeneration therapy: generation of functional organs from pluripotent stem cells]. (2011) (3)
Expression of Rh blood group gene transcripts in human leukocytes. (1994) (3)
[Generation of functional organs from pluripotent stem cells]. (2013) (3)
Human Immunodeficiency Virus Type 1 Vpr Modifies Cell Proliferation via Multiple Pathways (1999) (2)
Thy-1 inhibits mitogen-induced Ca2+ oscillation in ras-transformed mouse fibroblasts. (1992) (2)
A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice (2007) (2)
Reactive oxygen species in hematopoietic stem cells affect culture outcomes under inflammatory conditions (2015) (2)
Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells (2011) (2)
Stepwise Signaling and Low Oxygen Promote Hematopoietic Progenitor Emergence From Human Pluripotent Stem Cells (2011) (2)
CRISPR/Cas9 + AAV-mediated Intra-embryonic Gene Knocking in Mice. (2019) (2)
Bloodlines of haematopoietic stem cell research in Japan (2008) (2)
Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. (2019) (2)
Chimpanzee and pig-tailed macaque iPSCs: Improved culture and generation of primate cross-species embryos. (2022) (2)
Single-cell analysis identifies EpCAM+/CDH6+/TROP-2− cells as human liver progenitors (2018) (2)
A transmembrane trap method for efficient cloning of genes encoding proteins possessing transmembrane domain. (2001) (2)
Altered Immune Responsiveness in Patients with Chronic Glomerulonephritis (1989) (2)
30 – Phenotype of Mouse Hematopoietic Stem Cells (2004) (2)
Development A Role for Pref-1 and HES-1 in Thymocyte (1999) (2)
Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice (2015) (2)
A highly efficient reporter system for identifying and characterizing in vitro expanded hematopoietic stem cells (2021) (2)
Establishment in Culture of Expanded Potential Stem Cells (2017) (2)
Streamlined and quantitative detection of chimerism using digital PCR (2022) (2)
73 APPLICATION OF THE HOLLOW FIBER VITRIFICATION METHOD TO THE CRYOPRESERVATION OF HIGHLY CRYOSENSITIVE EMBRYOS (2015) (2)
Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells (2020) (2)
The cytoplasmic domain of the CD8 α-chain is required for its interaction with p56lck (1990) (2)
[Isolation and characterization of the hematopoietic stem cell]. (1995) (2)
Genetically engineered pigs manifesting pancreatic agenesis with severe diabetes (2020) (2)
Structure and expression of the gene encoding CD8 alpha chain (Leu-2/T8). (1989) (2)
326 GENERATION OF A DOUBLE-TRANSGENIC PIG WITH PANCREAS-SPECIFIC GREEN AND LIVER-SPECIFIC RED FLUORESCENCE (2013) (1)
Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner. (2015) (1)
Functional Analysis of SRSF2 Mutations in Myelodysplastic Syndromes and Related Disorders (2011) (1)
Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo. (2009) (1)
Removal of sperm tail using trypsin and pre-activation of oocyte facilitates intracytoplasmic sperm injection in mice and rats (2022) (1)
Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma (2011) (1)
Characterization of the mouse interleukin-13 receptor alpha1 gene. (2000) (1)
Evidence for the Involvement of CXCR4 Signaling in In Vivo Self-Renewal of Transplanted Hematopoietic Stem Cells (2011) (1)
Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2020) (1)
Generation of Blood Cells from Human Ips Cells in Vitro through the Hematopoietic Progenitors Concentrated within the Unique Structures, Ips-Sac. (2008) (1)
Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease (2015) (1)
In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation (2022) (1)
Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation (2020) (1)
Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells. (2016) (1)
Epigenetic Memory Enables the Dominant Generation of Adult-Type Erythrocytes From Human Induced Pluripotent Stem Cells (2010) (1)
Identification of a Novel cDNA Clone Encoding Protein Tyrosine Kinase in Murine Skin (1994) (1)
In vivo and ex vivo haematopoietic stem cell expansion. (2020) (1)
Streamlined and quantitative detection of chimerism in mouse tissue using digital PCR (2020) (1)
Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation (2011) (1)
Ex vivo mouse hematopoietic stem cell expansion using polyvinyl alcohol (2019) (1)
Use of polyvinyl alcohol for CAR T cell expansion (2020) (1)
A truncated erythropoietin receptor as a dominant negative regulator for cell growth and prevention of apoptosis (1994) (1)
[Potential usefulness of human iPS cells on the generation of platelets]. (2011) (1)
strain cannot encode a (1991) (1)
The Cytokine Signal Inhibitor Lnk Promotes αIIbβ3 Integrin Outside-In Signaling through β3 Tyrosine Phosphorylation in Platelets. (2007) (1)
A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice (2008) (1)
MT1-MMP Is Required for Hematopoietic Maturation in the BM Niche. (2009) (1)
Biological Analysis of SRSF2 Mutations in Leukemogenesis (2012) (1)
49 PRACTICAL APPLICATION OF THE HOLLOW FIBER VITRIFICATION METHOD FOR CRYOPRESERVATION OF MAMMALIAN EMBRYOS (2014) (1)
In vivo clonal analysis of aging hematopoietic stem cells (2020) (1)
Improving the safety of iPSC-derived T cell therapy (2022) (1)
A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies. (2009) (1)
HEMATOPOIESIS AND STEM CELLS Role of SOX 17 in hematopoietic development from human embryonic stem cells (2013) (1)
Hematopoietic stem cell chimerism: relationships between degree of chimerism, T cell clonal deletion, and graft survival. (1994) (1)
CD61/ Integrin β3 Ligation Contributes to the Thrombopoietin-Mediated Niche Function of Mouse Hematopoietic Stem Cells. (2009) (1)
Characterization of the mouse CD8 beta chain-encoding gene promoter region (2007) (1)
Hematopoietic Stem Cells for Regenerative Medicine (2009) (1)
The cytoplasmic domain of the CD8 alpha-chain is required for its interaction with p56lck. (1990) (1)
M2 macrophage exosomes regulate hematopoiesis & resolve inflammation in atherosclerosis via microrna cargo (2020) (1)
Corrigendum to “Cell cycle dependence of boron uptake from two boron compounds used for clinical neutron capture therapy” [Cancer Lett. 187 (2002) 135–141] (2005) (1)
Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells. (2009) (0)
DOWN-REGULATION OF SALL4 INHIBITS TUMOR GROWTH IN HEPATOCELLULAR CARCINOMA (2010) (0)
Title Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells (2019) (0)
Twelve-color Chimerism Analysis after HLA-mismatched Hematopoietic Cell Transplantation Using Anti-HLA Antibody and Spectral Flow Cytometer (2012) (0)
Abstract 17293: Hyperglycemia Enhances Pro-Inflammatory Properties of Macrophage-Derived Exosomes to Drive Hematopoiesis in Apolipoprotein E-Deficient Mouse (2020) (0)
Response : A Truncated Erythropoietin Receptor and Cell Death (1993) (0)
3103 – DEVELOPMENT OF EX VIVO HEMATOPOIETIC STEM CELL ASSAYS USING A HIGHLY SELECTIVE EXPANSION SYSTEM (2022) (0)
Transfusion therapy by blood platelets derived from embryonic stem cells or induced pluripotent stem cells (2008) (0)
Expression of Endomucin, a CD34-Like Sialomucin, Marks Definitive Hematopoietic Stem Cells throughout Development. (2004) (0)
Abstract 4602: Recurrent pathway mutations of multiple components of cohesin complex in myeloid neoplasms. (2013) (0)
Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Patients with Down Syndrome (2010) (0)
Analysis of Physical Characteristic of Hematopoietic Cells (2015) (0)
Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins (2016) (0)
Tmtsp , a Novel Gene Encoding a Cell Surface Protein Highly Specific to Hematopoietic Stem and Endothelial Cells. (2004) (0)
Use of Animal Models for the Study of Stem Cell Biology (2009) (0)
Abstract 408: ApoE Regulation of Hematopoiesis Suppresses Atherosclerosis by Reducing Adaptive Immunity in Hyperlipidemic Mice (2018) (0)
Mechanical guidance of self-condensation patterns of differentiating progeny (2022) (0)
Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes (2021) (0)
Development of Antigen Specific T Cells After HLA-Mismatched Umbilical Cord Blood Transplantation (2011) (0)
Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin (2010) (0)
Selective Activation of STAT5 Unveils Its Role in the Maintenance of Hematopoietic Stem Cells and the Development of Myeloproliferative Disorder. (2004) (0)
Lymphoid Lineage Restriction in Hematopoietic Stem Cells through Their First Division. (2004) (0)
[Diversity of hematopoietic stem cells]. (2005) (0)
Author Correction: Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2018) (0)
Author Correction: Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2018) (0)
Role Of Sf3b1 On Hematopoiesis (2013) (0)
Maintenance and expansion of human hematopoietic stem and progenitor cells in the presence of defined factors alone (2015) (0)
Mammalian epigenetics in biology and medicine ’ . Subject Areas : health and disease and epidemiology Keywords : stem cells , pluripotency , induced pluripotent stem cells , embryonic stem cells (2012) (0)
In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation (2022) (0)
Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation (2019) (0)
Efficient genaration of rabbit pluripotent stem cells (2017) (0)
Single amino acid substitutions determine mouse CD8 allotypes: epitope mapping of mouse CD8 (2005) (0)
3017 – ESTABLISHMENT OF A PLATFORM FOR EX VIVO GENE EDITING IN MULTIPOTENT HEMATOPOIETIC STEM CELLS (2021) (0)
Irradiated Bone Marrow Environment Impairs Hematopoietic Stem Cells by Exposure to Tumor Necrosis Factor a. (2010) (0)
3042 – CAS9-AAV6 GENE CORRECTION OF AUTOLOGOUS HSCS IMPROVES SICKLE CELL DISEASE ERYTHROPOIESIS IN MICE (2020) (0)
Metalloproteinase Regulation Determines Integrin αIIbβ3 Function and Enhances the Capacity of ES Cell-Derived Platelets. (2006) (0)
Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells (2016) (0)
SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia (2020) (0)
Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells (2016) (0)
Haematopoietic stem cell self-renewal in vivo and ex vivo (2020) (0)
Development and Regeneration of Hematopoietic Stem Cells (2016) (0)
Large-scale in vivo CRISPR screens identify SAGA complex members as a key regulators of HSC lineage commitment and aging (2022) (0)
MT1-MMP Plays a Critical Role In the Modulation of Hematopoiesis. (2010) (0)
A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease (2017) (0)
31 PRODUCTION EFFICIENCY OF GENE KNOCKOUT PIGS USING GENOME EDITING AND SOMATIC CELL CLONING (2015) (0)
Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells (2017) (0)
3202 – METABOLIC PROFILING OF MOUSE HEMATOPOIETIC STEM CELL SELF-RENEWAL AT SINGLE-CELL RESOLUTION (2022) (0)
Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (0)
361: The Pharmacodynamic Analysis between Cyclosporine a (CsA) and Cytokine Profiles of CD4+ T Lymphocytes for the Development of Optimized Immunosuppressive Therapy with CsA after Unrelated Cord Blood Transplantation (CBT) (2008) (0)
Identification of Fcδ/μ receptor expressed on B lymphocytes and macrophages (2001) (0)
Mouse Full-Length cDNA Encyclopedia Targeting a Complex Transcriptome: The Construction of the (2006) (0)
Author Correction: Investigation of Cas9 antibodies in the human eye (2022) (0)
Large-Scale Clonal Analys is Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment Graphical (0)
Cell Stem Cell Essential Role of Foxo 3 a in Self-Renewal of HSCs (0)
Low Incidence of Cytomegalovirus Infection Associated with Rapid Cell-Mediated Immune Reconstitution after Cord Blood Transplantation Using Full Conditioning Regimen Containing 12Gy Total Body Irradiation. (2006) (0)
Cytometry technologies for analysis of very small numbers of cells (LL2-5) Chairperson: Shigeo Koyasu (2010) (0)
cells and interleukin-7 Support of early B-cell differentiation in mouse fetal liver by stromal (2011) (0)
Running title : Generation of oocyte from xenogenic PGC (2014) (0)
Branched-Chain Amino Acid Depletion Conditions Bone Marrow for HSCT Avoiding Amino Acid Imbalance-Associated Toxicity (2018) (0)
Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system (2016) (0)
Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance (2017) (0)
[Technics of monoclonal antibody production with hybridomas and their medical application]. (1981) (0)
Correction: A Comprehensive System for Generation and Evaluation of Induced Pluripotent Stem Cells Using piggyBac Transposition (2014) (0)
26 IN VIVO EXOGENIC ORGAN GENERATION WITH ORGANOGENESIS-DISABLED CLONED PIGS AS A PLATFORM (2014) (0)
A Plasmin Inhibitor Prevents Lethal Acute Graft-Versus-Host Disease in Mice (2011) (0)
A Chemical Approach for Ex Vivo Expansion of Human Hematopoietic Stem Cells (2011) (0)
Title : Clock gene Bmal 1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2013) (0)
Exploiting the Organ Niche for Interspecies Organogenesis (2018) (0)
Cytokine-signal inhibitor Lnk upregulates integrin αIIbβ3 signaling in platelets (2006) (0)
Hematopoietic stem cells (+iPS) (PP-010) (2010) (0)
In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements (2011) (0)
Development by Kinase-Inactive ZAP-70 Thymocyte - CD8 - Demonstrates Inhibition of CD4 An Improved Retroviral Gene Transfer Technique (2012) (0)
Direct and Continuous Inhibition of ADAM17 Using a Novel Selective Inhibitor Restores Functional Platelet Yield From Human Pluripotent Stem Cells (2011) (0)
[Recent progress in stem cell biology and its implications for future medicine]. (2008) (0)
Organ transplantation (PP-076) (2010) (0)
Differentiation of Mature Eosinophils From Human Embryonic and Induced Pluripotent Stem Cells. (2010) (0)
Clonal Analysis of Progressive Maturation of Erythroid Cells from Human Embryonic Stem Cell-Derived Definitive Hematopoiesis. (2007) (0)
PROSPECTIVE IDENTIFICATION AND PURIFICATION OF MULTI-POTENT HEPATIC STEM CELLS(Developmental Biology)Proceedings of the Seventy-First Annual Meeting of the Zoological Society of Japan (2000) (0)
Megakaryocyte Lineage Commitment in Hematopoietic Stem Cells (2011) (0)
colony formation and an inhibitory effect of IL-1 alpha A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B- cell (2011) (0)
Molecular Cloning of Murine Lymphocyte Differentiation Antigen Ly- 1 and Its Predicted Structure (1986) (0)
Long-term and multilineage bone marrow reconstitution in normal untreated recipients. (1996) (0)
Expression and Characterization of Leucocyte Antigens (1984) (0)
Molecular cloning ofLyt-2, amembraneglycoprotein marking a subset ofmouseTlymphocytes: Molecular homology toitshuman counterpart, Leu-2/T8, andtoimmunoglobulin variable regions (1985) (0)
Use of cytokines for efficient introduction of foreign genes into the hematopoietic stem cell. (1994) (0)
[Purification and characterization of the hematopoietic stem cell]. (2000) (0)
Biological and genetic characterization of the role of SRSF2 mutations in the pathogenesis of myelodysplastic syndromes (2015) (0)
A retrospective analysis of germline competence in rat embryonic stem cell lines (2012) (0)
MT1-MMP Regulates Hematopoiesis Through HIF-Mediated Chemo-/Cytokine Release From the Bone Marrow Niche, (2011) (0)
An optimized Sendai viral vector platform for reprogramming to naive pluripotency (2022) (0)
human bone marrow Enrichment of interleukin-2-responsive natural killer progenitors in (2011) (0)
Human hematopoietic stem/progenitor cells hibernate in vascular niche harboring GFAP-expressing cells (2013) (0)
Clonal analysis in vivo unveils atypical dynamics of aged hematopoietic stem cells (2016) (0)
Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML (2012) (0)
Proof of Benefit in Multiple-Cord Blood Transplantation Evidenced By Early Hematopoietic Reconstitution (2015) (0)
Transmission of lethal phenotype in a Mendelian fashion by genetically modified pigs that underwent blastocyst complementation (2014) (0)
Negative Hematopoietic Scaffold Lnk Upregulates Integrin Outside-In Signaling in Platelets. (2005) (0)
LAS Seminar 1 (2018) (0)
Novel Functions for a Fibrinolytic Pathway in Controlling the Stem Cell Niche. (2006) (0)
Méthode de production d'un animal chimère (2014) (0)
Rapid Chimerism – Switch of Lymphocytes and Phenotypic Conversion of Naïve T Cells Early After Cord Blood Transplantation (2011) (0)
Stem cells and regeneration medicine (2002) (0)
Adaptor Protein Lnk Negatively Controls the Likelihood of Self-Renewal in Hematopoietic Stem Cells. (2006) (0)
Kinase-Inactive ZAP-70 Thymocyte Development by - CD8 - Technique Demonstrates Inhibition of CD4 An Improved Retroviral Gene Transfer (1998) (0)
The generation of functional organ by way of in utero transplantation (2017) (0)
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats (2019) (0)
Generation of Tfap2c‐T2A‐tdTomato knock‐in reporter rats via adeno‐associated virus‐mediated efficient gene targeting (2022) (0)
324 PRODUCTION OF GENETICALLY MODIFIED PIGS BY ARTIFICIAL REPRODUCTIVE TECHNOLOGIES USING FROZEN EPIDIDYMAL SPERM (2013) (0)
Dissecting the valine dependency of hematopoietic stem cell function (2017) (0)
[Use of FACS for the isolation of stem cells]. (2003) (0)
LASER-SCANNING FLOW CYTOMETER WITH A THREE-DIMENSIONAL MICROFLUIDIC CHIP (2008) (0)
Conditions for the successful engraftment of hepatocyte progenitors injected into the spleen. (1996) (0)
GENERATION OF FUNCTIONAL ORGANS FROM IPS CELLS: TOWARD THE NEXT GENERATION OF REGENERATIVE MEDICINE (INVITED SPEAKERS) (2011) (0)
Simultaneous generation of vascular endothelial cells and hematopoietic cells from pluripotent stem cells by blastocyst complementation (2017) (0)
Abstract 2894: Cardiac Mast Cells Cause Atrial Fibrillation Through PDGF-A-mediated Atrial Fibrosis in Pressure-overloaded Hearts (2009) (0)
Identification of immature podocyte specific antigen using retrovirus-mediated gene transfer and cell sorting (2005) (0)
Comprehensive Analysis of Surface Antigens on Adult T-Cell Leukemia/Lymphoma (ATL) Cells and Search for ATL-Initiating Cell Markers (2014) (0)
Nucleic Acids Research Isolation and characterization of the gene for the marine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2 (2005) (0)
Choice Between T and B Lymphocytes A Mouse Carrying Genetic Defect in the (0)
[iPSC-derived rejuvenated T-cell therapy for Epstein-Barr virus-associated lymphomas]. (2018) (0)
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures. (2023) (0)
Requirement forCD8P8 Chain inPositive Selection ofCD8-Lineage TCells (2016) (0)
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2017) (0)
Epidermal Growth Factor-like Domain 7 Promotes Hematopoietic Stem Cell Expansion and Increases Myeloid-Megakaryocytic Lineage Priming through beta3 Integrin (2014) (0)
Human iPSC Generation from Antigen-Specific T Cells. (2019) (0)
Flow Cytometric Analysis of Donor-Recipient Chimerism Using Anti-HLA Antibody after HLA-Mismatched Cord Blood Transplantation. (2007) (0)
Identification of CD34lo/−kit+sca+lin− cells in HOECHST33342 side population (Sp) Of the mouse bone marrow cells (2000) (0)
An interspecies barrier to tetraploid complementation and chimera formation (2018) (0)
Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin (2011) (0)
Altered humoral immune reactivity in patients with chronic glomerulonephritis (1991) (0)
Contribution of T-Cell Reconstitution during the Early Phase after Cord Blood Transplantation to Favorable Clinical Outcomes. (2004) (0)
255. Potent Cancer Immunotherapy with Dendritic Cells Generated from Genetically Modified Hematopoietic Stem Cells (2004) (0)
Regenerative medicine for digestige organs and kidney (2013) (0)
[Self-renewal potential of hematopoietic stem cells]. (2002) (0)
Novel Therapeutic Approach To Graft-Versus-Host Disease With Allele-Specific Anti-HLA Monoclonal Antibody (2013) (0)
Hemat opoietic Homeostasis against Diet-Induced Systemic Stress Graphical Abstract Highlights (2018) (0)
Clock gene Bmal 1 is dispensable for intrinsic properties of murine hematopoietic stem cells (2014) (0)
In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects (2018) (0)
330. Genetic Modification of Murine Embryonic Stem Cells by the Gene Silencing Resistance Retroviral Vector GCDsap (2004) (0)
Anephrogenic phenotype induced by SALL1 gene knockout in pigs (2019) (0)
Identification of a novel cDNA clone encoding protein tyrosine kinase in murine skin. (1994) (0)
Abstract of Public Open Special Lecture at Symposium (2005) (0)
Myeloid Lineage Restriction Is Prior to and Independent of Lymphoid Lineage Restriction. (2006) (0)
Bioluminescent Tracking of Human Induced Pluripotent Stem Cells In Vitro and In Vivo. (2022) (0)
Integrin- (cid:1) v (cid:2) 3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells (2011) (0)
Dietary created niche for non-myeloablative hematopoietic stem cell transplantation (2015) (0)
Long-term ex vivo expansion of mouse hematopoietic stem cells (2020) (0)
Efficient scarless genome editing in human pluripotent stem cells (2018) (0)
Is donor-derived long-term and multilineage hematopoiesis established after liver transplantation? (1998) (0)
Use of cytometry technology for the study of stem cell biology (2009) (0)
In Vitro Myelo-Lymphoid Colony Formation by Mouse Hematopoietic Stem Cells (2008) (0)
Control of self-renewal activity of hematopoietic stem cells by spred1 (2014) (0)
A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells (2014) (0)
Isolation and Characterization of CD34-Low/Negative Mouse Hematopoietic Stem Cells (2000) (0)
Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse (2017) (0)
Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep (2018) (0)
Hematopoiesis Arises Independent of Vasculogenesis in the Early Mouse Embryos. (2006) (0)
spreading machinery development and spreading: implications for platelet biogenesis and The WAVE2/Abi1 complex differentially regulates megakaryocyte (2013) (0)
iPSC-derived Rejuvenated T-cell Therapy for Extranodal NK/T-cell Lymphoma, Nasal Type (2020) (0)
LONG-TERM CULTURE OF FETAL LIVER CELLS USING THREE-DIMENSIONAL POROUS POLYMER (1999) (0)
hematopoietic progenitors vitro via ES-sacs, VEGF-promoted structures that concentrate Generation of functional platelets from human embryonic stem cells in (2013) (0)
Simple and efficient method of rat ICSI (2017) (0)
Hematopoietic stem cells (+iPS) (WS-010) Chairpersons: Hiromitsu Nakauchi, Haruhiko Koseki (2010) (0)
Prospective identification and enrichment of self-renewing multipotential hepatic stem cells by flow cytometric cell sorting (2001) (0)
pluripotency Definitive proof for direct reprogramming of hematopoietic cells to (2009) (0)
Proceedings of the 2nd Meeting of the Asian Cellular Therapy Organization (2011) (0)
Results Cross-Circulatory System Is Stabilized 7 to 10 Days After Parabiotic Surgery (2015) (0)
Molecular analysis of SJL and AKR lymphomas (1986) (0)
In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells from Induced Pluripotent Stem Cells through Hemogenic Endothelium (2016) (0)
The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer (2011) (0)
Progress in Stem-Cell Research and New Medical Care (2014) (0)
A New Strategy to Overcome the Cell Dose Barrier to Umbilical Cord Blood Transplants: A Proof of Early Hematopoietic Reconstitution By Combined Multiple Units of Allogeneic Stem/Progenitor Cells (2014) (0)
Conversion of iPS derived hepatic progenitors into scalable, functional and developmentally relevant human organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold engineered from collagen-coated pores of defined size (2018) (0)
Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep (2020) (0)
Development of conditional hematopoietic cell abrogation system by CD45 promoter - Diphtheria Toxin Receptor (DTR) (2015) (0)
[110th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: 1. Frontier of the regenerative medicine; 1) Regenerative medicine for digestive organs and kidney]. (2013) (0)
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (0)
[Physiological and pathological roles of the truncated erythropoietin receptor]. (1997) (0)
[Utilization of the ES/iPS cell technology for hematopoietic stem cell transplantation]. (2012) (0)
Unique Gain-of-Function of Mutated c-CBL Tumor Suppresor in Myeloid Neoplasms. (2009) (0)
Human Embryonic Stem Cell-Derived “NET-Like” Structure Serves as a Hematopoietic Progenitor Niche and Favors Generation of Mature Megakaryocytes and Functional Platelets. (2006) (0)
Practice and technical barrier of intra-embryonic large cassette knock-in by Adeno-Associated Viral vector with Cas9 ribonucleoprotein electroporation. (2019) (0)
Homeostatic regulation of hematopoietic stem cells by the interaction of niche factors (2015) (0)
Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors (2017) (0)
LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells (2019) (0)
Protection of Transplanted Hematopoietic Stem Cells from Inflammatory Recipient Marrow Environment through Specific TNF-α Signal Blockade (2015) (0)
HSC-independent lymphopoiesis (HEM1P.228) (2015) (0)
Detection of lineage-specific STAT5A phosphorylation in peripheral blood cells from a myeloproliferative neoplasm model mouse using multicolor flow cytometry (2010) (0)
Analysis of Lymphocyte Subsets in Human Diseases (1983) (0)
2001 - LONG-TERM EX VIVO EXPANSION OF FUNCTIONAL HEMATOPOIETIC STEM CELLS (2019) (0)
Role of spred1 in the regulation of self-renewal and aging of hematopoietic stem cells (2015) (0)
A new gene transfer system for hematopoietic stem cells under physiological condition (2015) (0)

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