Hiromu Sakurai
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Chemistry
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(Suggest an Edit or Addition)Hiromu Sakurai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Antidiabetic vanadium(IV) and zinc(II) complexes (2002) (441)
- An antitumor promoter from Moringa oleifera Lam. (1999) (382)
- Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. (2002) (327)
- Hypervalent Iodine-Induced Nucleophilic Substitution of para-Substituted Phenol Ethers. Generation of Cation Radicals as Reactive Intermediates (1994) (314)
- Active-oxygen scavenging activity of plant extracts. (1995) (205)
- Orally active and long-term acting insulin-mimetic vanadyl complex:bis(picolinato)oxovanadium (IV). (1995) (184)
- Detection of hydrogen peroxide and hydroxyl radicals in murine skin fibroblasts under UVB irradiation. (1995) (181)
- Chemiluminescent detection and imaging of reactive oxygen species in live mouse skin exposed to UVA. (2000) (173)
- Current state for the development of metallopharmaceutics and anti-diabetic metal complexes. (2008) (150)
- Mechanism on insulin-like action of vanadyl sulfate: studies on interaction between rat adipocytes and vanadium compounds. (1995) (149)
- Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats. (1990) (149)
- A new concept: the use of vanadium complexes in the treatment of diabetes mellitus. (2002) (147)
- Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice. (1999) (144)
- Biospeciation of antidiabetic VO(IV) complexes (2008) (135)
- Development of new insulinomimetic zinc(II) picolinate complexes with a Zn(N2O2) coordination mode: structure characterization, in vitro, and in vivo studies (2002) (106)
- Mechanism for a new antitumor vanadium complex: hydroxyl radical-dependent DNA cleavage by 1,10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide. (1995) (101)
- SOD activities of the copper complexes with tripodal polypyridylamine ligands having a hydrogen bonding site (2001) (99)
- Insulin-Mimetic Action of Vanadyl Complexes (1990) (94)
- Long-term acting and orally active vanadyl-methylpicolinate complex with hypoglycemic activity in streptozotocin-induced diabetic rats (1997) (93)
- Oral administration of a zinc complex improves type 2 diabetes and metabolic syndromes. (2006) (92)
- Age‐dependent generation of reactive oxygen species in the skin of live hairless rats exposed to UVA light (2003) (91)
- Inhibition of HIV-1 infection by zinc group metal compounds. (1999) (91)
- Possible mode of action for insulinomimetic activity of vanadyl(IV) compounds in adipocytes. (2006) (91)
- An orally active antidiabetic vanadyl complex, bis(1-oxy-2-pyridinethiolato)oxovanadium(IV), with VO(S2O2) coordination mode; in vitro and in vivo evaluations in rats. (2000) (88)
- A new orally active insulin-mimetic vanadyl complex: bis(pyrrolidine-N-carbodithioato)oxovanadium (IV). (1994) (83)
- Detection of oxovanadium (IV) and characterization of its ligand environment in subcellular fractions of the liver of rats treated with pentavalent vanadium(V). (1980) (83)
- Detection of reactive oxygen species in the skin of live mice and rats exposed to UVA light: a research review on chemiluminescence and trials for UVA protection. (2005) (80)
- Ternary complex formation between VO(IV)-picolinic acid or VO(IV)-6-methylpicolinic acid and small blood serum bioligands. (2000) (80)
- Speciation of insulin-mimetic VO(IV)-containing drugs in blood serum. (2000) (80)
- Separation of vanadocytes: Determination and characterization of vanadium ion in the separated blood cells of the ascidian, Ascidia ahodori (1987) (79)
- Insulinomimetic bis(maltolato)zinc(II) complex: blood glucose normalizing effect in KK-A(y) mice with type 2 diabetes mellitus. (2001) (76)
- Estimation of the age of human bloodstains by electron paramagnetic resonance spectroscopy: long-term controlled experiment on the effects of environmental factors. (2005) (75)
- Generation of active oxygen species from advanced glycation end-products (AGEs) during ultraviolet light A (UVA) irradiation and a possible mechanism for cell damaging. (1999) (75)
- The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes. (2004) (74)
- Structure-dependent metallokinetics of antidiabetic vanadyl-picolinate complexes in rats: studies on solution structure, insulinomimetic activity, and metallokinetics. (2002) (71)
- Enhancement by streptozotocin of O− 2 radical generation by the xanthine oxidase system of pancreatic β‐cells (1988) (71)
- Chemistry and Biochemistry of Insulin-Mimetic Vanadium and Zinc Complexes. Trial for Treatment of Diabetes Mellitus (2006) (69)
- Antidiabetic copper(II)-picolinate: impact of the first transition metal in the metallopicolinate complexes. (2007) (69)
- New Vanadium(V) Complexes with Salicylaldehyde Semicarbazone Derivatives: Synthesis, Characterization, and in vitro Insulin‐Mimetic Activity − Crystal Structure of [VvO2(salicylaldehyde semicarbazone)] (2004) (69)
- New Insulin-Mimetic Zinc (II) Complexes; Bis-maltolato Zinc(II) and Bis-(2-hydroxypyridine-N-oxido) Zinc(II) with Zn(O4) Coordination Mode (2000) (69)
- The Pharmacology of the Insulinomimetic Effect of Zinc Complexes (2005) (69)
- In vitro study of the insulin-like action of vanadyl-pyrone and -pyridinone complexes with a VO(O4) coordination mode (2001) (68)
- Differential role of catalase and glutathione peroxidase in cultured human fibroblasts under exposure of H2O2 or ultraviolet B light (1998) (68)
- Orally active antioxidative copper(II) aspirinate: synthesis, structure characterization, superoxide scavenging activity, and in vitro and in vivo antioxidative evaluations (2005) (67)
- A new type of orally active anti-diabetic Zn(II)-dithiocarbamate complex. (2007) (67)
- Structural and redox requirements for the action of anti-diabetic vanadium compounds. (2014) (66)
- Orally administrated aluminum-maltolate complex enhances oxidative stress in the organs of mice. (2004) (65)
- A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. (2006) (64)
- Possible involvement of singlet oxygen species as multiple oxidants in p450 catalytic reactions. (2005) (61)
- A new insulin-mimetic bis(allixinato)zinc(II) complex: structure–activity relationship of zinc(II) complexes (2004) (61)
- Bis(allixinato)oxovanadium(IV) complex is a potent antidiabetic agent: studies on structure-activity relationship for a series of hydroxypyrone-vanadium complexes. (2006) (61)
- A new diagnostic method for chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma based on serum metallothionein, copper, and zinc levels. (2002) (60)
- A new halogenated antidiabetic vanadyl complex, bis(5-iodopicolinato)oxovanadium(IV): in vitro and in vivo insulinomimetic evaluations and metallokinetic analysis (2001) (59)
- The therapeutic potential of insulin-mimetic vanadium complexes (2003) (58)
- A new family of insulin-mimetic vanadium complexes derived from 5-carboalkoxypicolinates. (2003) (57)
- In vivo coordination structural changes of a potent insulin-mimetic agent, bis(picolinato)oxovanadium(IV), studied by electron spin-echo envelope modulation spectroscopy. (1999) (56)
- Increased generation of hydrogen peroxide possibly from mitochondrial respiratory chain after UVB irradiation of murine fibroblasts. (1997) (56)
- Synthesis and insulin-mimetic activities of metal complexes with 3-hydroxypyridine-2-carboxylic acid. (2005) (55)
- Molecular mechanism of antidiabetic zinc–allixin complexes: regulations of glucose utilization and lipid metabolism (2008) (54)
- Metallokinetic analysis of disposition of vanadyl complexes as insulin-mimetics in rats using BCM-ESR method. (2000) (54)
- Action mechanism of bis(allixinato)oxovanadium(IV) as a novel potent insulin-mimetic complex: regulation of GLUT4 translocation and FoxO1 transcription factor (2007) (54)
- New insulinomimetic zinc(II) complexes of alpha-amino acids and their derivatives with Zn(N2O2) coordination mode. (2001) (54)
- Amelioration of insulin resistance in diabetic ob/ob mice by a new type of orally active insulin-mimetic vanadyl complex: bis(1-oxy-2-pyridinethiolato)oxovanadium(IV) with VO(S(2)O(2)) coordination mode. (2001) (52)
- Insulin-mimetic vanadyl—dithiocarbamate complexes (1998) (52)
- Reaction of β-Alkannin (Shikonin) with Reactive Oxygen Species: Detection of β-Alkannin Free Radicals (2000) (52)
- Scavenging effects of dihydric and polyhydric phenols on superoxide anion radicals, studied by electron spin resonance spectrometry (1992) (51)
- Unusual generation of hydroxyl radicals in hepatic copper-metallothionein of LEC (Long-Evans cinnamon) rats in the presence of hydrogen peroxide. (1994) (51)
- Vanadium distribution in rats and DNA cleavage by vanadyl complex: implication for vanadium toxicity and biological effects. (1994) (51)
- Synthesis and Properties of Octaethylporphinato(arenethiolato)iron(III) Complexes with Intramolecular NH···S Hydrogen Bond: Chemical Function of the Hydrogen Bond (1998) (51)
- Synthesis and insulinomimetic activities of novel mono- and tetranuclear oxovanadium(IV) complexes with 3-hydroxypyridine-2-carboxylic acid. (2004) (50)
- New antidiabetic vanadyl–pyridone complexes: effect of equivalent transformation of coordinating atom in the ligand (2003) (50)
- Metallo-allixinate complexes with anti-diabetic and anti-metabolic syndrome activities. (2010) (49)
- Direct reaction between shikonin and thiols induces apoptosis in HL60 cells. (2002) (49)
- Uptake of hexavalent chromium by bovine erythrocytes and its interaction with cytoplasmic components; the role of glutathione. (1982) (47)
- Pharmacokinetic analysis of free radicals by in vivo BCM (Blood Circulation Monitoring)-ESR method. (1997) (47)
- Improvement of diabetes, obesity and hypertension in type 2 diabetic KKAy mice by bis(allixinato)oxovanadium(IV) complex. (2006) (47)
- EPR study on the interaction of hexavalent chromium with glutathione or cysteine: Production of pentavalent chromium and its stability (1988) (46)
- Partition of divalent and total manganese in organs and subcellular organelles of MnCl2-treated rats studied by ESR and neutron activation analysis. (1985) (46)
- Insulinomimetic Zn complex (Zn(opt)2) enhances insulin signaling pathway in 3T3-L1 adipocytes. (2007) (45)
- Metallokinetic study of zinc in the blood of normal rats given insulinomimetic zinc(II) complexes and improvement of diabetes mellitus in type 2 diabetic GK rats by their oral administration. (2002) (44)
- Aluminum compounds enhance lipid peroxidation in liposomes: insight into cellular damage caused by oxidative stress. (2007) (44)
- Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers. (2002) (43)
- Syntheses of vanadyl and zinc(II) complexes of 1-hydroxy-4,5,6-substituted 2(1H)-pyrimidinones and their insulin-mimetic activities. (2006) (43)
- Chemical structure-dependent differential effects of flavonoids on the catalase activity as evaluated by a chemiluminescent method. (2007) (43)
- A novel drug delivery system for type 1 diabetes: insulin-mimetic vanadyl-poly(gamma-glutamic acid) complex. (2006) (43)
- Insulin-mimetic vanadyl(IV) complexes as evaluated by both glucose-uptake and inhibition of free fatty acids (FFA)-release in isolated rat adipocytes. (2004) (42)
- Copper-metallothionein distribution in the liver of Long-Evans cinnamon rats: studies on immunohistochemical staining, metal determination, gel filtration and electron spin resonance spectroscopy. (1993) (42)
- Enhancement by streptozotocin of O2- radical generation by the xanthine oxidase system of pancreatic beta-cells. (1988) (42)
- Antioxidative Compounds in the Extracts of Black Rice Brans (2006) (42)
- Microscopic acid dissociation constants of 3,4-dihydroxyphenylpropionic acid and related compounds, and 3,4-dihydroxyphenylalanine (DOPA). (1977) (42)
- Microionization constants of sulphonamides. (1980) (42)
- Role of vanadium in treating diabetes (1999) (41)
- Anti-diabetes effect of Zn(II)/carnitine complex by oral administration. (2003) (40)
- Vanadium in Ascidians (1990) (40)
- Protective activity of hamamelitannin on cell damage of murine skin fibroblasts induced by UVB irradiation. (1995) (39)
- Unusual accumulation of copper related to induction of metallothionein in the liver of LEC rats. (1992) (39)
- Generation of active oxygen species from advanced glycation end-products (AGE) under ultraviolet light A (UVA) irradiation. (1997) (39)
- Generation of nitric oxide from streptozotocin (STZ) in the presence of copper(II) plus ascorbate: implication for the development of STZ-induced diabetes. (1998) (38)
- ESR analysis with long-chain alkyl spin labels in bovine blood platelets. Relationship between the increase in membrane fluidity by alcohols and phenolic compounds and their inhibitory effects on aggregation. (1990) (38)
- α-Tocopherol Increases the Intracellular Glutathione Level in HaCaT Keratinocytes (2002) (38)
- Protective effects of baicalein against cell damage by reactive oxygen species. (1998) (37)
- A new nitric oxide (NO) releaser: spontaneous NO release from FK409. (1995) (37)
- Reduction of vanadate(V) to oxovanadium(IV) by cysteine and mechanism and structure of the oxovanadium(IV)–cysteine complex subsequently formed (1981) (37)
- Hamamelitannin as a new potent active oxygen scavenger (1994) (36)
- Bis(6-ethylpicolinato)oxovanadium(IV) complex with normoglycemic activity in KK-A(y) mice. (2002) (36)
- Dysfunction of dermal fibroblasts induced by advanced glycation end-products (AGEs) and the contribution of a nonspecific interaction with cell membrane and AGEs. (2002) (36)
- Photocontrol of spatial orientation and DNA cleavage activity of copper(II)-bound dipeptides linked by an azobenzene derivative. (2008) (36)
- Direct evidence of heme-tert-butyl peroxide adduct formation demonstrated by simultaneous ESR and optical measurements (1989) (34)
- Peroxyl radical scavenging activities of hamamelitannin in chemical and biological systems. (1995) (34)
- A new candidate for insulinomimetic vanadium complex: synergism of oxovanadium(IV)porphyrin and sodium ascorbate. (2004) (34)
- Pharmacokinetic study and trial for preparation of enteric-coated capsule containing insulinomimetic vanadyl compounds: implications for clinical use. (2003) (34)
- Aminoacid-derivatised picolinato-oxidovanadium(IV) complexes: characterisation, speciation and ex vivo insulin-mimetic potential. (2009) (34)
- Binding constant of VIVO to transferrin (2006) (33)
- Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes. (2006) (33)
- Generation of alloxan free radicals in chemical and biological systems: implication in the diabetogenic action of alloxan. (1989) (33)
- Solution equilibrium characterization of insulin-mimetic Zn(II) complexes. (2006) (33)
- Pharmacokinetic study on gastrointestinal absorption of insulinomimetic vanadyl complexes in rats by ESR spectroscopy (2001) (32)
- Syntheses, structures, stability, and insulin-like activities of peroxovanadium(V) complexes with a heteroligand. (2001) (32)
- Evidence for the improvement of noninsulin-dependent diabetes mellitus in KKAy mice with daily oral administration of bis(6-methylpicolinato)oxovanadium(IV) complex. (1999) (32)
- Visualization and characterization of UVB-induced reactive oxygen species in a human skin equivalent model (2008) (32)
- Alpha-glucosidase inhibitory effect of anti-diabetic metal ions and their complexes. (2009) (31)
- Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential. (2009) (31)
- Suppressive Effect of Caffeic Acid and its Derivatives on the Generation of UVA-induced Reactive Oxygen Species in the Skin of Hairless Mice and Pharmacokinetic Analysis on Organ Distribution of Caffeic Acid in ddY Mice (2006) (31)
- Characterization and Insulin-Mimetic Potential of Oxidovanadium(IV) Complexes Derived from Monoesters and -carboxylates of 2,5-Dipicolinic Acid (2006) (31)
- Anion-exchange resin modified with bismuthiol-II, as a new functional resin for the selective collection of selenium(IV). (1984) (30)
- Investigation of the insulin-like properties of zinc(II) complexes of 3-hydroxy-4-pyridinones: identification of a compound with glucose lowering effect in STZ-induced type I diabetic animals. (2011) (30)
- Identification of free radical species derived from caffeic acid and related polyphenols (2007) (30)
- Metallokinetic characteristics of antidiabetic bis(allixinato)oxovanadium(IV)-related complexes in the blood of rat (2007) (30)
- Copper-metallothionein induction in the liver of LEC rats. (1992) (29)
- New Zinc(II) Complexes with Tetradentate Amino Acid Derivatives: Structure Characterization, Solution Chemistry, and in vitro Insulinomimetic Activity (2002) (29)
- STEREOSPECIFIC AND STRUCTURE-DEPENDENT INSULIN-MIMETIC OXOVANADIUM(IV) COMPLEXES WITH N, N'-ETHYLENEBIS(AMINO ACIDS) (1999) (29)
- Memory Deficit in Mice Administered Aluminum–maltolate Complex (2006) (29)
- Protective effects of hydroxybenzoic acids and their esters on cell damage induced by hydroxyl radicals and hydrogen peroxides. (1997) (29)
- A New Type of Orally Active Insulin-Mimetic Vanadyl Complex: Bis(1-oxy-2-pyridinethiolato)oxovanadium(IV) with VO(S2O2) Coordination Mode (1999) (28)
- Potential insulinominetic agents of zinc(II) complexes with picolinamide derivatives: preparations of complexes, in vitro and in vivo studies. (2002) (28)
- Glucose lowering activity by oral administration of bis(allixinato)oxidovanadium(IV) complex in streptozotocin-induced diabetic mice and gene expression profiling in their skeletal muscles (2009) (28)
- Gem-bis(disubstitutedphosphinyl)alkanes—II: Extraction of uranium(VI) with bis(di-n-hexylphosphinyl)methane (1963) (28)
- Challenge of studies on the development of new Zn complexes (Zn(opt)₂) to treat diabetes mellitus. (2011) (28)
- Novel 3-hydroxy-4-pyridinonato oxidovanadium(IV) complexes to investigate structure/activity relationships. (2009) (28)
- Metal- and photo-induced cleavage of DNA by podophyllotoxin, etoposide, and their related compounds. (1991) (28)
- New Bioactive Zinc(II) Complexes with Peptides and Their Derivatives: Synthesis, Structure, and In Vitro Insulinomimetic Activity (2004) (28)
- Reaction of biological phenolic antioxidants with superoxide generated by cytochrome P-450 model system. (1983) (28)
- Crystal structure of an L-cysteine methyl ester-vanadyl(IV) complex (1988) (27)
- Overview and Frontier for the Development of Metallopharmaceutics (2010) (26)
- HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone), an anti-lipid-peroxidative compound: its chemical and biochemical characterizations. (1998) (26)
- Chemical speciation of insulinomimetic VO(IV) complexes of pyridine-N-oxide derivatives: binary and ternary systems. (2003) (26)
- DNA cleavage by hydroxyl radicals generated in a vanadyl ion-hydrogen peroxide system. (1992) (26)
- Purification of vanadium binding substance from the blood cells of the tunicate, Ascidia sydneiensis samea. (1986) (26)
- Cell to cell interaction between mesangial cells and macrophages induces the expression of monocyte chemoattractant protein-1 through nuclear factor-kappaB activation. (2000) (26)
- Novel vanadyl complexes with quinoxaline N(1),N(4)-dioxide derivatives as potent in vitro insulin-mimetic compounds. (2006) (25)
- Antidiabetic zinc(II)‐N ‐acetyl‐L‐cysteine complex: Evaluations of in vitro insulinomimetic and in vivo blood glucose‐lowering activities (2007) (25)
- SYNTHESES, STRUCTURES, AND INSULIN-LIKE ACTIVITIES OF TWO VANADYL COMPLEXES; VO(GEG)(H2O) AND VO(MEM)(H2O) (1998) (25)
- Insulinomimetic zinc(II) complexes with natural products: in vitro evaluation and blood glucose lowering effect in KK-Ay mice with type 2 diabetes mellitus. (2003) (25)
- Evaluation of insulin-mimetic activities of vanadyl and zinc(II) complexes from the viewpoint of heterocyclic bidentate ligands. (2009) (25)
- Essential role of singlet oxygen species in cytochrome P450-dependent substrate oxygenation by rat liver microsomes. (2005) (25)
- Coordination-dependent ESR spectra of copper(II) complexes with a CuN4 type coordination mode : Relationship between ESR parameters and stability constants or redox potentials of the complexes (1996) (25)
- Detection of vanadyl‐nitrogen interaction in organs of the vanadyl‐treated rat: electron spin echo envelope modulation study (1995) (24)
- Oral administration of Bis(aspirinato)zinc(II) complex ameliorates hyperglycemia and metabolic syndrome-like disorders in spontaneously diabetic KK-A(y) mice: structure-activity relationship on zinc-salicylate complexes. (2011) (24)
- Protective activity of hamamelitannin on cell damage induced by superoxide anion radicals in murine dermal fibroblasts. (1995) (24)
- In vitro alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide. (2005) (24)
- Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn(II) and Mo(VI). Thermodynamic stability and insulin-mimetic activity. (2010) (24)
- Anti-inflammatory, antimutagenicity, and antitumor-promoting activities of mahogany seeds, Swietenia macrophylla (Meliaceae) (1996) (24)
- Real-time chemiluminescent imaging and detection of reactive oxygen species generated in the UVB-exposed human skin equivalent model. (2006) (23)
- A Zinc(II)/poly(gamma-glutamic acid) complex as an oral therapeutic for the treatment of type-2 diabetic KKAy mice. (2009) (23)
- Scavenging Activities of α-, β- and γ-Thujaplicins against Active Oxygen Species (1997) (23)
- ATP(adenosine triphosphate)-vanadyl complex. (1982) (23)
- ESR characterization and metallokinetic analysis of Cr(V) in the blood of rats given carcinogen chromate(VI) compounds. (1999) (23)
- Pentosidine in advanced glycation end-products (AGEs) during UVA irradiation generates active oxygen species and impairs human dermal fibroblasts. (2001) (23)
- Implication of the differential roles of metallothionein 1 and 2 isoforms in the liver of rats as determined by polyacrylamide-coated capillary zone electrophoresis. (2004) (23)
- An improved diagnostic method for chronic hepatic disorder: analyses of metallothionein isoforms and trace metals in the liver of patients with hepatocellular carcinoma as determined by capillary zone electrophoresis and inductively coupled plasma-mass spectrometry. (2006) (22)
- Cysteine methyl ester-oxovanadium(IV) complex, preparation and characterization (1980) (22)
- A New Anti-diabetic Zn(II)–Hinokitiol (β-Thujaplicin) Complex with Zn(O4) Coordination Mode (2005) (22)
- An Extremely High Insulin-Mimetic Activity of Bis(1,4-dihydro-2-methyl-1-phenyl- 4-thioxo-3-pyridinolato)zinc(II) Complex (2002) (22)
- Amelioration of Hyperglycemia and Metabolic Syndromes in Type 2 Diabetic KKAy Mice by Poly(γ‐glutamic acid)oxovanadium(IV) Complex (2007) (22)
- Microscopic Acid Dissociation Constants of 3, 4-Dihydroxyphenethylamine (Dopamine) (1978) (21)
- Dating of human blood by electron spin resonance spectroscopy (2004) (21)
- A Highly Potent Insulin–mimetic Zinc(II) Complex with a Zn(S2O2) Coordination Mode: Bis(1,6-dimethyl-3-hydroxy-5-methoxy-2-pentyl-1,4-dihydropyridine-4-thionato)zinc(II) (2005) (21)
- Superoxide dismutase mimetic activities of metal complexes of L-2(2-pyridyl)-1-pyrroline-5-carboxylic acid (pyrimine). (1993) (21)
- Optical absorption and EPR studies on a six-coordinate iron(III)–tetramesitylporphyrin–hydrogen peroxide complex having a nitrogenous axial ligand (1995) (21)
- A family of insulinomimetic zinc(II) complexes of amino ligands with Zn(Nn) (n=3 and 4) coordination modes. (2005) (21)
- Models for coordination site of cytochrome P-450, characterization of hemin-thiolato complexes with S, O, and N donor ligands by electronic absorption and electron spin resonance spectra. (1985) (21)
- Syntheses, Structures, and Insulin-like Activities of Oxovanadium(IV) Complexes with Tetra- and Penta-dentate Histidine Derivatives (1998) (21)
- Novel Mn(II)Mn(III)Mn(II) trinuclear complexes with carbohydrate bridges derived from seven-coordinate manganese(II) complexes with N-glycoside. (2000) (20)
- Oxovanadium(IV)–Porphyrin Complex as a Potent Insulin-Mimetic. Treatment of Experimental Type 1 Diabetic Mice by the Complex [meso-Tetrakis(4-sulfonatophenyl)porphyrinato]oxovanadate(IV)(4−) (2006) (19)
- A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders. (2002) (19)
- alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes. (2002) (19)
- Synthesis of nitrated oligo-N-methylpyrrole carboxamide derivatives and their photochemical DNA cleaving activities (1990) (19)
- Cytochrome P-450-butyl peroxide complex detected by ESR. (1993) (18)
- A possible model of hemoprotein-peroxide complexes formed in an iron-tetraphenylporphyrin system. (1986) (18)
- A New Insulin‐mimetic Vanadyl Complex, (N‐Pyridylmethylaspartate)oxovanadium(IV) with VO(N2O2) Coordination Mode, and Evaluation of its Effect on Uptake of D‐Glucose by Ehrlich Ascites Tumour Cells (1999) (18)
- Mechanism of hepatorenal syndrome in rats of Long-Evans Cinnamon strain, an animal model of fulminant Wilson's disease. (1999) (18)
- Glutathione-hemin complex as a cytochrome P-450 model characterization of the complex and its aromatic oxidation activities. (1981) (18)
- A zinc(II)-glycine complex is an effective inducer of metallothionein and removes oxidative stress. (2007) (18)
- Evaluation of superoxide scavenging activities of hamamelis extract and hamamelitannin. (1993) (18)
- Generation and distribution of reactive oxygen species in the skin of hairless mice under UVA: studies on in vivo chemiluminescent detection and tape stripping methods (2006) (17)
- Characterization of aniline hydroxylation by a cytochrome P-450 model and a possible hydroxylation mechanism. (1980) (17)
- The interaction of aliphatic nitro compounds with the liver microsomal monooxygenase system. (1980) (17)
- Isolation, characterization and thiol exchange reaction of penicillamine selenotrisulfides. (1986) (17)
- Insulinomimetic Zn(II) complexes as evaluated by both glucose-uptake activity and inhibition of free fatty acids release in isolated rat adipocytes. (2008) (17)
- 31p- and 13C-NMR study of the ATP(adenosine triphosphate)-vanadyl complex. (1982) (17)
- EPR characterization of vanadyl (IV) species in blood cells of ascidians. (1987) (17)
- In vivo L-band ESR and quantitative pharmacokinetic analysis of stable spin probes in rats and mice. (1999) (17)
- Investigation of a CuII–Poly(γ‐Glutamic Acid) Complex in Aqueous Solution and its Insulin‐Mimetic Activity (2007) (17)
- Enteric‐coating capsulation of insulinomimetic vanadyl sulfate enhances bioavailability of vanadyl species in rats (2002) (16)
- Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex. (2008) (16)
- Mononuclear to Tetranuclear Structural Transformation in Vanadyl Complexes of 3-Hydroxypyridine-2-carboxylic Acid (H2hpic) (2002) (16)
- Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats. (2005) (16)
- Occurrence of aromatic methyl migration (NIH-shift) during oxidation of p-methylanisole by hemin-thiolester complex as a cytochrome P-450 model. (1982) (16)
- Development of functional resins by modification of ion-exchange resins and their application to analytical chemistry (1987) (15)
- Determination of Four Active Oxygen Species Such as H2O2, •OH, •O2 −, and 1O2 by Luminol and CLA-Chemiluminescence Methods and Evaluation of Antioxidative Effects of Hydroxybenzoic Acids (1997) (15)
- Evidence for singlet oxygen involvement in rat and human cytochrome P450-dependent substrate oxidations. (2002) (15)
- Specific binding of vanadyl ion (VO2+) with thiolate of the cysteine-34 residue in serum albumin, demonstrated by CD spectroscopy and kinetic property (2003) (15)
- Absorption of mercury by solutions containing oxidants (1983) (15)
- Alterations in manganese and iodide contents in human thyroid tumors; a correlation between the contents of essential trace elements and the states of malignancy. (1990) (15)
- Action mechanism of metallo-allixin complexes as antidiabetic agents (2008) (15)
- Generation of superoxide in a cobalt(II) tetraphenylporphyrin-thiolate-oxygen system (1982) (15)
- A Zn(II)–glycine complex suppresses UVB‐induced melanin production by stimulating metallothionein expression (2008) (15)
- Inhibitory effect of CuSO₄ on α-glucosidase activity in ddY mice. (2010) (14)
- SUPEROXIDE DISMUTASE MIMETIC COMPLEX OF MN(II)/N, N-BIS(2-PYRIDYLMETHYL)-(S)-HISTIDINE (1999) (14)
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- Antidiabetic activity of Zn(II) complexes with a derivative of L-glutamine (2005) (13)
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- A model system for drug metabolism in isolated hepatocytes. Oxidation of cyclohexene by metalloporphyrin complexes (1985) (12)
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- Ethyl oleate oxygenation by cytochrome P-450 models (1988) (11)
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- Synthesis, structure analysis, solution chemistry, and in vitro insulinomimetic activity of novel oxovanadium(IV) complexes with tripodal ligands containing an imidazole group derived from amino acids (2003) (11)
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- ORTHO-and PARA-selectivity in aromatic hydroxylation by iron-thiol and hemin-thiol complexes. (1975) (0)
- Improvement of aging-associated cardiac and endothelial dysfunction by the copper (II) aspirinate complex (2009) (0)
- Antidiabeti czinc(II)- N-acetyl-L-cysteine complex :Evaluation so fi nvitro insulinomimeti can di nviv oblood glucose-lowering activities (2007) (0)
- Current State for the Development of Metallopharmaceutics and Antidiabetic Metal Complexes (2009) (0)
- THE DECREMENTS OF SERUM ZINC AND COPPER LEVELS IN ELDERLY INPATIENTS (1997) (0)
- Copper-metallothionein induction and free radical formation in LEC rats (1997) (0)
- VII-C-3 Evidence for the Improvement of Noninsulin-Dependent Diabetes Mellitus in KKAy Mice with Daily Oral Administration of Bis ( 6-methylpicolinato ) oxovanadium ( IV ) Complex FUJISAWA (2001) (0)
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What Schools Are Affiliated With Hiromu Sakurai?
Hiromu Sakurai is affiliated with the following schools:
