Hironobu Ihn

Q: What Schools Are Affiliated With Hironobu Ihn

Hironobu Ihn is affiliated with the following schools: University of Tokyo, Kumamoto University

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Hironobu Ihn

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#7875

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#11151

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#4909

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#6247

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Philosophy

Hironobu Ihn's Degrees

PhD Medical Science University of Tokyo
Doctorate Medicine University of Tokyo

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Hironobu Ihn's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. (1996) (438)
Characterization of SIS3, a Novel Specific Inhibitor of Smad3, and Its Effect on Transforming Growth Factor-β1-Induced Extracellular Matrix Expression (2006) (400)
Pathogenesis of fibrosis: role of TGF-β and CTGF (2002) (305)
Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. (1995) (292)
Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype (1998) (235)
Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts. (2004) (212)
A randomized double-blind trial of intravenous immunoglobulin for pemphigus. (2009) (209)
Increased Expression of Integrin αvβ3 Contributes to the Establishment of Autocrine TGF-β Signaling in Scleroderma Fibroblasts1 (2005) (195)
Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment. (2018) (192)
Impaired IL-17 Signaling Pathway Contributes to the Increased Collagen Expression in Scleroderma Fibroblasts (2012) (188)
The circulating microRNA-221 level in patients with malignant melanoma as a new tumor marker. (2011) (183)
Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor β receptors (2001) (180)
Pathogenesis of fibrosis: role of TGF-beta and CTGF. (2002) (178)
Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis (2010) (170)
Myasthenic crisis and polymyositis induced by one dose of nivolumab (2016) (165)
Transcriptional regulation of the human alpha2(I) collagen gene. Combined action of upstream stimulatory and inhibitory cis-acting elements. (1996) (150)
Oncostatin M Stimulates Transcription of the Human α2(I) Collagen Gene via the Sp1/Sp3-binding Site* (1997) (149)
Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts (2006) (146)
Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis. (1998) (144)
Efficacy and safety of ixekizumab treatment for Japanese patients with moderate to severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis: Results from a 52‐week, open‐label, phase 3 study (UNCOVER‐J) (2016) (140)
The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma (2013) (133)
TGF-β–Mediated Downregulation of MicroRNA-196a Contributes to the Constitutive Upregulated Type I Collagen Expression in Scleroderma Dermal Fibroblasts (2012) (130)
Antihistone antibodies in systemic sclerosis. Association with pulmonary fibrosis. (1994) (123)
Tenascin-C upregulation by transforming growth factor-β in human dermal fibroblasts involves Smad3, Sp1, and Ets1 (2004) (121)
Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis. (2011) (121)
miR-150 down-regulation contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3. (2013) (116)
Autocrine TGF- signaling in the pathogenesis of systemic sclerosis (2008) (116)
Involvement of αvβ5 integrin–mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts (2005) (116)
Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts. (2005) (114)
Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype. (1998) (112)
Down-Regulation of mir-424 Contributes to the Abnormal Angiogenesis via MEK1 and Cyclin E1 in Senile Hemangioma: Its Implications to Therapy (2010) (110)
Sp3 is a transcriptional activator of the human α2(I) collagen gene (1997) (107)
Antihistone antibodies in patients with localized scleroderma. (1993) (105)
microRNA‐mediated keratinocyte hyperproliferation in psoriasis vulgaris (2011) (104)
Growth regulation in scleroderma fibroblasts: increased response to transforming growth factor-beta 1. (1995) (101)
Increased production of interleukin 6 and interleukin 8 in scleroderma fibroblasts. (1998) (100)
Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma (2016) (98)
Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts1 (2003) (96)
Circulating miR‐142‐3p levels in patients with systemic sclerosis (2012) (92)
Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. (1999) (91)
Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblasts via the ERK1/2 and JNK pathways (2009) (91)
microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. (2012) (91)
Characterization of autoantibodies to endothelial cells in systemic sclerosis (SSc): association with pulmonary fibrosis (2000) (91)
Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK (2012) (89)
Demonstration of interleukin-2, interleukin-4 and interleukin-6 in sera from patients with localized scleroderma (1995) (89)
Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma (2009) (89)
IL-4 Up-Regulates the Expression of Tissue Inhibitor of Metalloproteinase-2 in Dermal Fibroblasts Via the p38 Mitogen-Activated Protein Kinase-Dependent Pathway1 (2002) (88)
Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma (2017) (88)
Interleukin-13 Stimulates the Transcription of the Human α2(I) Collagen Gene in Human Dermal Fibroblasts* (2004) (87)
Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts. (2006) (86)
HPGCD Outperforms HPBCD as a Potential Treatment for Niemann‐Pick Disease Type C During Disease Modeling with iPS Cells (2015) (86)
Phosphatidylinositol 3-Kinase Is Involved in α2(I) Collagen Gene Expression in Normal and Scleroderma Fibroblasts1 (2004) (85)
Regulation of fibrogenic/fibrolytic genes by platelet‐derived growth factor C, a novel growth factor, in human dermal fibroblasts (2005) (84)
Involvement of αvβ5 Integrin in the Establishment of Autocrine TGF-β Signaling in Dermal Fibroblasts Derived from Localized Scleroderma (2006) (79)
Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis. (2008) (77)
Increased serum levels of soluble vascular cell adhesion molecule-1 and E-selectin in patients with systemic sclerosis. (1998) (71)
Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-beta signaling in cultured scleroderma fibroblasts. (2005) (70)
Increased Expression Levels of Integrin αvβ5 on Scleroderma Fibroblasts (2004) (70)
Prevention of UVB Radiation-induced Epidermal Damage by Expression of Heat Shock Protein 70* (2009) (70)
Clinical characteristics associated with antihistone antibodies in patients with localized scleroderma. (1994) (69)
A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid. (2017) (69)
Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis (2017) (68)
Oncostatin M Stimulates the Growth of Dermal Fibroblasts Via a Mitogen-Activated Protein Kinase-Dependent Pathway1 (2000) (68)
Involvement of alphavbeta5 integrin-mediated activation of latent transforming growth factor beta1 in autocrine transforming growth factor beta signaling in systemic sclerosis fibroblasts. (2005) (64)
Long non‐coding RNA TSIX is upregulated in scleroderma dermal fibroblasts and controls collagen mRNA stabilization (2016) (63)
Phase 1b study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced melanoma (KEYNOTE-041) (2017) (63)
Constitutive phosphorylation of focal adhesion kinase is involved in the myofibroblast differentiation of scleroderma fibroblasts. (2005) (62)
Clinical and laboratory features of scleroderma patients developing skeletal myopathy (2005) (61)
Ultrasound measurement of skin thickness in systemic sclerosis. (1995) (61)
Sensitive detection of melanoma metastasis using circulating microRNA expression profiles (2013) (59)
Increased transcriptional activities of transforming growth factor beta receptors in scleroderma fibroblasts. (2002) (59)
Efficacy and safety of nivolumab in Japanese patients with previously untreated advanced melanoma: A phase II study (2017) (59)
The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma. (2002) (56)
Angiopoietin-like Protein 2 Accelerates Carcinogenesis by Activating Chronic Inflammation and Oxidative Stress (2013) (55)
Upregulated expression of transforming growth factor-beta receptors in dermal fibroblasts of skin sections from patients with systemic sclerosis. (2002) (55)
Prognostic Significance of CD169+ Lymph Node Sinus Macrophages in Patients with Malignant Melanoma (2015) (55)
microRNA-7 down-regulation mediates excessive collagen expression in localized scleroderma (2012) (54)
Circulating miR-29a levels in patients with scleroderma spectrum disorder. (2011) (54)
A randomized, double-blind, placebo-controlled trial: intravenous immunoglobulin treatment in patients with diffuse cutaneous systemic sclerosis. (2013) (53)
Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts. (2006) (53)
Serum levels of tissue inhibitor of metalloproteinases 2 in patients with systemic sclerosis. (2000) (52)
Clinical and histopathological characteristics and survival analysis of 4594 Japanese patients with melanoma (2019) (52)
Increased accumulation of extracellular thrombospondin-2 due to low degradation activity stimulates type I collagen expression in scleroderma fibroblasts. (2012) (52)
Serum long non‐coding RNA, snoRNA host gene 5 level as a new tumor marker of malignant melanoma (2016) (51)
Serum aldolase level is a useful indicator of disease activity in eosinophilic fasciitis. (1995) (50)
Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1 (2005) (50)
Clinical usefulness of anti-RNA polymerase III antibody measurement by enzyme-linked immunosorbent assay. (2009) (50)
Serum levels of soluble CD163 in patients with systemic sclerosis (2012) (49)
Increased serum levels of miR-1266 in patients with psoriasis vulgaris. (2012) (48)
Effects of hepatocyte growth factor on the expression of type I collagen and matrix metalloproteinase-1 in normal and scleroderma dermal fibroblasts. (2005) (48)
Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma. (2006) (48)
Increased phosphorylation and activation of mitogen-activated protein kinase p38 in scleroderma fibroblasts. (2005) (48)
Adiponectin expression is decreased in the involved skin and sera of diffuse cutaneous scleroderma patients (2011) (47)
Altered expression of CD63 and exosomes in scleroderma dermal fibroblasts. (2016) (46)
Diagnostic criteria, severity classification and guidelines of localized scleroderma (2018) (46)
Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptions. (2014) (46)
Circulating intercellular adhesion molecule-1 in the sera of patients with systemic sclerosis: enhancement by inflammatory cytokines. (1997) (45)
Antagonistic effects of TNF-alpha on TGF-beta signaling through down-regulation of TGF-beta receptor type II in human dermal fibroblasts. (2003) (45)
Circulating levels of soluble CD30 are increased in patients with localized scleroderma and correlated with serological and clinical features of the disease. (2000) (44)
The wound/burn guidelines – 6: Guidelines for the management of burns (2016) (44)
Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis (1997) (43)
Tsukushi controls the hair cycle by regulating TGF-β1 signaling. (2012) (42)
CD109 expression levels in malignant melanoma. (2010) (42)
α2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts (2005) (42)
Clinical significance of serum levels of soluble interleukin‐2 receptor in patients with localized scleroderma (1996) (40)
Diagnostic criteria, severity classification and guidelines of eosinophilic fasciitis (2018) (40)
Clinical evaluation of scleroderma spectrum disorders using a points system (1992) (40)
Detection of hair-microRNAs as the novel potent biomarker: evaluation of the usefulness for the diagnosis of scleroderma. (2013) (40)
Increased levels of circulating intercellular adhesion molecule-1 in patients with localized scleroderma. (1994) (40)
Scleroderma, fibroblasts, signaling, and excessive extracellular matrix (2005) (39)
Epidermal Growth Factor Induces Fibronectin Expression in Human Dermal Fibroblasts via Protein Kinase C δ Signaling Pathway (2004) (39)
Expression of matrix metalloproteinase-13 is controlled by IL-13 via PI3K/Akt3 and PKC-δ in normal human dermal fibroblasts. (2011) (39)
Suppression of Melanin Production by Expression of HSP70* (2010) (39)
Discoidin domain receptor 2-microRNA 196a-mediated negative feedback against excess type I collagen expression is impaired in scleroderma dermal fibroblasts. (2013) (38)
Platelet derived growth factor induced tenascin‐C transcription is phosphoinositide 3‐kinase/Akt‐dependent and mediated by Ets family transcription factors (2006) (38)
High seroprevalence of Helicobacter pylori infection in patients with systemic sclerosis: association with esophageal involvement. (1998) (38)
The human histocompatibility leukocyte antigen (HLA) haplotype is associated with the onset of postherpetic neuralgia after herpes zoster (2004) (37)
The role of angiopoietin-like protein 2 in pathogenesis of dermatomyositis. (2012) (36)
Epidemiological survey of Vibrio vulnificus infection in Japan between 1999 and 2003 (2008) (35)
Increased expression levels of integrin alphavbeta5 on scleroderma fibroblasts. (2004) (35)
Demonstration of interleukin 8 in serum samples of patients with localized scleroderma. (1994) (34)
Kinesin family member 20A is a novel melanoma-associated antigen. (2012) (34)
Eosinophilic fasciitis: From pathophysiology to treatment. (2019) (34)
Serum Adhesion Molecule Levels as Prognostic Markers in Patients with Early Systemic Sclerosis: A Multicentre, Prospective, Observational Study (2014) (34)
Serum chemokine levels as prognostic markers in patients with early systemic sclerosis: a multicenter, prospective, observational study (2012) (34)
The Successful Treatment of Prurigo pigmentosa with Macrolide Antibiotics (2001) (34)
The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma (2013) (33)
Investigation of FOXM1 as a Potential New Target for Melanoma (2015) (32)
Amelanotic metastatic melanoma in a patient with oculocutaneous albinism. (1993) (32)
CD163 expression is increased in the involved skin and sera of patients with systemic lupus erythematosus. (2012) (32)
Evaluation of sentinel node biopsy for cutaneous squamous cell carcinoma (2014) (31)
Antigen specificity of antihistone antibodies in localized scleroderma. (1994) (30)
Translationally Controlled Tumor Protein Is a Novel Biological Target for Neurofibromatosis Type 1-associated Tumors* (2014) (30)
Serum levels of soluble interleukin 6 receptor and soluble gp130 are elevated in patients with localized scleroderma. (2000) (30)
NUP160-SLC43A3 is a novel recurrent fusion oncogene in angiosarcoma. (2015) (30)
Upregulation of tenascin-C expression by IL-13 in human dermal fibroblasts via the phosphoinositide 3-kinase/Akt and the protein kinase C signaling pathways. (2006) (29)
Decreased miR-7 expression in the skin and sera of patients with dermatomyositis. (2013) (29)
Serum levels of soluble vascular endothelial growth factor receptor‐2 in patients with systemic sclerosis (2009) (29)
Hair miR‐29a levels are decreased in patients with scleroderma (2013) (28)
The prevalence and clinical significance of anti-U1 RNA antibodies in patients with systemic sclerosis. (2003) (28)
Adult-onset neurological degeneration in a patient with Cockayne syndrome and a null mutation in the CSB gene. (2008) (28)
Antibodies to centromere and centriole in scleroderma spectrum disorders. (1994) (28)
Sp3 is a transcriptional activator of the human alpha2(I) collagen gene. (1997) (28)
Effects of the immunosuppressant rapamycin on the expression of human α2(I) collagen and matrix metalloproteinase 1 genes in scleroderma dermal fibroblasts. (2014) (28)
Multiple Antigen-targeted Immunotherapy With α-Galactosylceramide–loaded and Genetically Engineered Dendritic Cells Derived From Embryonic Stem Cells (2009) (27)
The prevalence of melanocytic nevi on the soles in the Japanese population. (2009) (27)
Immunohistochemical characterization of the cellular infiltrate in localized scleroderma (2008) (27)
Phase II study of i.v. interferon‐gamma in Japanese patients with mycosis fungoides (2014) (27)
Efficacy and safety of dose escalation of infliximab therapy in Japanese patients with psoriasis: Results of the SPREAD study (2016) (27)
Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblasts. (2003) (26)
Diagnostic criteria, severity classification and guidelines of systemic sclerosis (2018) (26)
The expression of HER-2 in extramammary Paget's disease. (2011) (26)
Epidermal growth factor affects the synthesis and degradation of type I collagen in cultured human dermal fibroblasts. (2006) (26)
Down-regulation of miR-223 contributes to the formation of Gottron's papules in dermatomyositis via the induction of PKCɛ. (2013) (26)
Long‐term follow up of nivolumab in previously untreated Japanese patients with advanced or recurrent malignant melanoma (2019) (25)
Immune checkpoint inhibitors in the onset of myasthenia gravis with hyperCKemia (2018) (25)
Expression analysis of multiple microRNAs in each patient with scleroderma (2013) (25)
Scleroderma dermal fibroblasts overexpress vascular endothelial growth factor due to autocrine transforming growth factor β signaling (2013) (25)
Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice. (2013) (25)
Prediction of additional lymph node positivity and clinical outcome of micrometastases in sentinel lymph nodes in cutaneous melanoma: A multi‐institutional study of 450 patients in Japan (2012) (25)
The expression of miR-124 increases in aged skin to cause cell senescence and it decreases in squamous cell carcinoma. (2016) (24)
Dysregulated interleukin-23 signalling contributes to the increased collagen production in scleroderma fibroblasts via balancing microRNA expression (2017) (24)
Plasma plasmin–α2‐plasmin inhibitor complex levels are increased in systemic sclerosis patients with pulmonary hypertension (2003) (24)
Measurement of anticardiolipin antibodies by ELISA using beta 2-glycoprotein I (beta 2-GPI) in systemic sclerosis. (1996) (24)
Down-regulation of microRNA-196a in the sera and involved skin of localized scleroderma patients (2014) (24)
EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin (2015) (23)
Association of Linear IgA Bullous Disease with Ulcerative Colitis: A Case of Successful Treatment with Infliximab (2013) (23)
Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy. (2008) (23)
Long‐term efficacy and safety results from an open‐label phase III study (UNCOVER‐J) in Japanese plaque psoriasis patients: impact of treatment withdrawal and retreatment of ixekizumab (2018) (23)
Tinea nigra showing a parallel ridge pattern on dermoscopy (2015) (23)
Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients (2016) (23)
Fixed food eruption caused by cashew nut. (2008) (22)
Tofacitinib for the treatment of moderate to severe chronic plaque psoriasis in Japanese patients: Subgroup analyses from a randomized, placebo‐controlled phase 3 trial (2017) (22)
Serum levels of interleukin‐1α in patients with systemic sclerosis (2013) (22)
Soluble CD4 and CD8 in serum from patients with localized scleroderma (1996) (22)
Serum concentration of procollagen type I carboxyterminal propeptide in localized scleroderma. (1994) (21)
Intravenous immunoglobulin treatment recovers the down-regulated levels of Th1 cytokines in the sera and skin of scleroderma patients. (2013) (21)
Clinical relevance of serum levels of matrix metallopeptidase‐2, and tissue inhibitor of metalloproteinase‐1 and ‐2 in patients with malignant melanoma (2008) (21)
Detection of hair root miR-19a as a novel diagnostic marker for psoriasis. (2013) (21)
miR‐424 levels in hair shaft are increased in psoriatic patients (2014) (21)
Transcription factor LSF (TFCP2) inhibits melanoma growth (2015) (21)
Expression of Let-7 family microRNAs in skin correlates negatively with severity of pulmonary hypertension in patients with systemic scleroderma☆ (2015) (20)
The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation (2017) (20)
Knockout of Endothelial Cell-Derived Endothelin-1 Attenuates Skin Fibrosis but Accelerates Cutaneous Wound Healing (2014) (20)
Prevalence of 52-kd and 60-kd Ro/SS-A autoantibodies in Japanese patients with polymyositis/dermatomyositis. (2002) (20)
Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors (2014) (20)
Submental perforator flap: Location and number of submental perforating vessels (2008) (20)
Spl phosphorylation induced by serum stimulates the human alpha2(I) collagen gene expression. (2001) (20)
Autoantibodies to pyruvate dehydrogenase complex in patients with systemic sclerosis. Possible role of anti-E1 alpha antibody as a serologic indicator for development of primary biliary cirrhosis. (1995) (20)
Analysis of expression pattern of serum microRNA levels in patients with psoriasis. (2014) (20)
Recurrent cutaneous eosinophilic vasculitis presenting as annular urticarial plaques. (2005) (19)
High-dose intravenous immunoglobulin infusion in polyarteritis nodosa (2006) (18)
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells. (2019) (18)
Oculocutaneous albinism type 3: a Japanese girl with novel mutations in TYRP1 gene. (2011) (18)
Rheumatoid factor isotypes in mixed connective tissue disease (2006) (18)
Tinea unguium caused by terbinafine‐resistant Trichophyton rubrum successfully treated with fosravuconazole (2019) (18)
[Cutaneous Cryptococcosis]. (2019) (17)
Differential expression of heat shock protein 105 in melanoma and melanocytic naevi (2008) (17)
Circulating microRNA associated with TNF-α signaling pathway in patients with plaque psoriasis. (2011) (17)
Transforming growth factor β‐inhibitor Repsox downregulates collagen expression of scleroderma dermal fibroblasts and prevents bleomycin‐induced mice skin fibrosis (2017) (17)
The wound/burn guidelines – 4: Guidelines for the management of skin ulcers associated with connective tissue disease/vasculitis (2016) (17)
Potential regulatory elements of the constitutive up-regulated alpha2(I) collagen gene in scleroderma dermal fibroblasts. (2006) (17)
Clinical features of scleroderma patients with contracture of phalanges (2007) (17)
The expression of human high molecular weight melanoma-associated antigen in acral lentiginous melanoma. (2010) (17)
Immunohistochemical characterization of the cellular infiltrate in discoid lupus erythematosus. (2011) (17)
Crizotinib-associated erythema multiforme in a lung cancer patient. (2015) (16)
MIRSNP rs2910164 of miR‐146a is associated with the muscle involvement in polymyositis/dermatomyositis (2014) (16)
Transglutaminase1 preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis. (2010) (16)
Identification and characterization of the novel centrosomal protein centlein. (2008) (16)
Autoantibodies to mitochondrial 2‐oxo‐acid dehydrogenase complexes in localized scleroderma (1996) (16)
Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C delta signaling pathway. (2004) (16)
Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis (2018) (16)
Decreased Interleukin‐20 Expression in Scleroderma Skin Contributes to Cutaneous Fibrosis (2014) (16)
Detection of antiribosomal P protein antibodies in patients with systemic sclerosis. (1995) (15)
Systemic lupus erythematosus associated with myasthenia gravis, pemphigus foliaceus and chronic thyroiditis after thymectomy (2017) (15)
The role of PSMB9 upregulated by interferon signature in the pathophysiology of cutaneous lesions of dermatomyositis and systemic lupus erythematosus (2016) (15)
Markedly increased levels of IL-6 and CA125 in pleural fluid of an elderly person with overlap syndrome of systemic sclerosis and systemic lupus erythematosus. (2001) (15)
Immunotherapy against Metastatic Melanoma with Human iPS Cell–Derived Myeloid Cell Lines Producing Type I Interferons (2015) (15)
Case report of cutaneous protothecosis caused by Prototheca wickerhamii designated as genotype 2 and current status of human protothecosis in Japan (2018) (15)
Achieved good response of S‐1 and docetaxel combination chemotherapy in two patients with metastatic extramammary Paget's disease (2017) (14)
Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway (2017) (14)
Skin microbiome in acral melanoma: Corynebacterium is associated with advanced melanoma (2020) (14)
The wound/burn guidelines – 3: Guidelines for the diagnosis and treatment for diabetic ulcer/gangrene (2016) (14)
Diagnostic and prognostic value of subcutaneous tissue biopsy in patients with cardiac amyloidosis. (2012) (14)
Serum levels of tenascin‐C in collagen diseases (2013) (14)
Serum concentrations of HGF are correlated with response to anti-PD-1 antibody therapy in patients with metastatic melanoma. (2019) (14)
Serum levels of matrix metalloproteinase‐13 in patients with eosinophilic fasciitis (2014) (14)
Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblasts. (2010) (14)
Serum miR-124 up-regulation as a disease marker of toxic epidermal necrolysis (2015) (14)
Multiple Eruptive Dermatofibromas with CD34+ Cells in a Patient with Hypertriglyceridemia (2003) (14)
Mitogenic activity of dermatofibrosarcoma protuberans is mediated via an extracellular signal related kinase dependent pathway. (2002) (14)
miR-205 down-regulation promotes proliferation of dermatofibrosarcoma protuberans tumor cells by regulating LRP-1 and ERK phosphorylation (2014) (13)
Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency[S] (2018) (13)
Differential effects of the immunosuppressant FK-506 on human alpha2(I) collagen gene expression and transforming growth factor beta signaling in normal and scleroderma fibroblasts. (2005) (13)
Activation of the extracellular signal-regulated kinases signaling pathway in squamous cell carcinoma of the skin. (2007) (13)
Anti-p53 antibodies in patients with dermatomyositis/polymyositis (2007) (13)
Regulatory mechanisms of collagen expression by interleukin-22 signaling in scleroderma fibroblasts. (2017) (13)
Overexpression of hepatocyte growth factor receptor in scleroderma dermal fibroblasts is caused by autocrine transforming growth factor β signaling. (2012) (13)
Fungal melanonychia caused by Candida parapsilosis successfully treated with oral fosravuconazole (2019) (13)
Cutaneous lymphoma in Japan, 2012-2017: A nationwide study. (2020) (13)
Investigation of prognostic factors for skin sclerosis and lung function in Japanese patients with early systemic sclerosis: a multicentre prospective observational study. (2012) (13)
Safety and tolerability of bosentan for digital ulcers in Japanese patients with systemic sclerosis: Prospective, multicenter, open‐label study (2017) (12)
A case of leg cellulitis caused by multidrug-resistant Streptococcus pseudoporcinus. (2018) (12)
Cutaneous hyalohyphomycosis by Scedosporium apiospermum in an immunocompromised patient (2011) (12)
IL-16 expression is increased in the skin and sera of patients with systemic sclerosis. (2019) (12)
The wound/burn guidelines – 2: Guidelines for the diagnosis and treatment for pressure ulcers (2016) (12)
Specific inhibition of human skin fibroblast chemotaxis to platelet-derived growth factor A-chain homodimer by transforming growth factor-β1 (2002) (12)
Serum miR-21 levels in patients with dermatomyositis. (2013) (12)
Altered dynamics of transforming growth factor β (TGF-β) receptors in scleroderma fibroblasts (2010) (12)
Juvenile pustular psoriasis associated with steroid withdrawal syndrome due to topical corticosteroid (2008) (12)
Differential predictive factors for cardiovascular events in patients with or without cancer history (2019) (12)
Adjuvant therapy with nivolumab versus ipilimumab after complete resection of stage III/IV melanoma: Japanese subgroup analysis from the phase 3 CheckMate 238 study (2019) (12)
Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus (2018) (12)
Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure. (2018) (12)
Photosensitivity and Acute Liver Insufficiency in Late-Onset Erythropoietic Protoporphyria with a Chromosome 18q Abnormality (2012) (11)
Significance of 5-S-Cysteinyldopa as a Marker for Melanoma (2020) (11)
The expression of SnoN in normal human skin and cutaneous keratinous neoplasms (2009) (11)
MicroRNAs that predict the effectiveness of anti-PD-1 therapies in patients with advanced melanoma. (2019) (11)
Correlated expression levels of endothelin receptor B and Plexin C1 in melanoma. (2015) (11)
Hypoxia accelerates the progression of angiosarcoma through the regulation of angiosarcoma cells and tumor microenvironment. (2019) (11)
Linear Connective Tissue Nevus (2007) (11)
Serum concentration of procollagen type I carboxyterminal propeptide in systemic sclerosis (1994) (11)
Cell division cycle‐associated protein 1 as a new melanoma‐associated antigen (2016) (11)
Serum levels of leptin receptor in patients with malignant melanoma as a new tumor marker (2013) (11)
Chronic sun exposure-related fusion oncogenes EGFR-PPARGC1A in cutaneous squamous cell carcinoma (2017) (11)
Circulating tumor necrosis factor-α DNA are elevated in psoriasis. (2020) (11)
Secukinumab‐induced interstitial pneumonia in a patient with psoriasis vulgaris (2017) (11)
Heliotrope‐like eruption mimicking dermatomyositis in a patient treated with imatinib mesylate for chronic myeloid leukemia (2006) (10)
Case of disseminated cutaneous Mycobacterium chelonae infection mimicking cutaneous vasculitis (2014) (10)
A Case of Fingernail Onychomycosis due to Aspergillus flavus. (2016) (10)
Case of neuro‐Behçet's disease successfully maintained a remission using infliximab for 2 years (2013) (10)
Decreased serum IL-7 levels in patients with systemic sclerosis. (2009) (10)
Antiubiquitin antibody in localised and systemic scleroderma. (1996) (10)
Serum cell‐free DNA levels are a useful marker for extramammary Paget disease (2019) (10)
Classification of 3097 patients from the Japanese melanoma study database using the American joint committee on cancer eighth edition cancer staging system. (2019) (10)
Case of paraneoplastic pemphigus with follicular lymphoma treated with rituximab (2013) (10)
Elevated soluble CD23 levels in the sera from patients with localized scleroderma (1996) (10)
Role of c‐Jun N‐terminal kinase isoforms in the cellular activity of melanoma cell lines (2013) (10)
Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts. (2007) (10)
High-dose intravenous immunoglobulin infusion in polyarteritis nodosa: report on one case and review of the literature. (2006) (10)
The expression profile of the toll-like receptor family in scleroderma dermal fibroblasts. (2014) (10)
Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis (2016) (10)
Successful treatment of dermatomyositis with high-dose intravenous immunoglobulin. (2006) (9)
Epidermal growth factor up-regulates transforming growth factor-β receptor type II in human dermal fibroblasts via p38 mitogen-activated protein kinase pathway (2007) (9)
Mice overexpressing integrin αv in fibroblasts exhibit dermal thinning of the skin. (2015) (9)
Eccrine angiomatous hamartoma with massive mucin deposition. (2005) (9)
Serum cytokine profiles are altered in patients with progressive infantile hemangioma. (2018) (9)
The proportion of lymphocytic inflammation with CD123-positive cells in lupus erythematous profundus predict a clinical response to treatment. (2014) (9)
Fascia lata onlay patch for repairing infected incisional hernias (2014) (9)
Combination chemotherapy with S-1 and docetaxel for cutaneous angiosarcoma resistant to paclitaxel. (2015) (9)
Ungual hyalohyphomycosis caused by Fusarium proliferatum in an immunocompetent patient (2017) (9)
Treatment of psoriasis with ustekinumab improved skin tightening in systemic sclerosis. (2017) (9)
Distribution of anti‐p80‐coilin autoantibody in collagen diseaseand various skin diseases (1997) (9)
Serum matrix metalloproteinase-3 in systemic sclerosis (2004) (9)
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity Via XCR1 + Dendritic Cells (2019) (9)
Clinical features of 80 cases of tinea faciei treated at a rural clinic in Japan. (2014) (8)
Biweekly gemcitabine therapy induces complete remission in cutaneous angiosarcoma resistant to multiple anticancer drugs (2015) (8)
GENERALIZED ERUPTIVE SYRINGOMA (2005) (8)
Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-β signaling in angiosarcoma. (2020) (8)
Improving Sun Protection Behaviour in Children: Study Design and Baseline Results of a Randomized Trial in Italian Elementary Schools (2003) (8)
Cell type‐specific regulation of the TGF‐β‐responsive α2(I) collagen gene by CpG methylation (2005) (8)
Expression of CD1a and CD86 on scleroderma Langerhans cells. (2008) (8)
Dots/globules on dermoscopy in nail‐apparatus melanoma (2014) (8)
Increased CCL22 expression in psoriatic skin predicts a good response to infliximab therapy (2014) (8)
Final results from phase II of combination with canerpaturev (formerly HF10), an oncolytic viral immunotherapy, and ipilimumab in unresectable or metastatic melanoma in second-or later line treatment (2019) (8)
Expression pattern of VEGFR-1, -2, -3 and D2-40 protein in the skin of patients with systemic sclerosis. (2011) (8)
Overexpression of cyclin‐dependent kinase 4 protein in extramammary Paget's disease (2019) (8)
Non-dermatophyte Mould Onychomycosis in Japan. (2020) (8)
Serum levels of soluble CD21 in patients with systemic sclerosis (2012) (8)
Pathogenesis of fibrosis: role of TGF-&bgr; and CTGF (2002) (8)
Impaired lymphangiogenesis due to excess vascular endothelial growth factor‐D/Flt‐4 signalling in the skin of patients with systemic sclerosis (2010) (8)
Quick detection of herpes viruses from skin vesicles and exudates without nucleic acid extraction using multiplex PCR. (2008) (8)
Bullous pemphigoid induced by furosemide (1993) (8)
This study was supported in part by a grant for scientific research from the Japanese Ministry of Education, Science, Sports and Culture, and by project research on intractable diseases from the Japanese Ministry of Health, Labour and Welfare. (2012) (7)
Proliferating tricholemmal cystic carcinoma: a case containing differentiated and dedifferentiated parts (2008) (7)
Enhanced CCR9 expression levels in psoriatic skin are associated with poor clinical outcome to infliximab treatment (2016) (7)
The wound/burn guidelines – 1: Wounds in general (2016) (7)
Cytokine expression profiles in the sera of cutaneous squamous cell carcinoma patients. (2016) (7)
Autoantibodies against calpastatin in sera from patients with systemic sclerosis. (1998) (7)
The wound/burn guidelines – 5: Guidelines for the management of lower leg ulcers/varicose veins (2016) (7)
Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets 1 and Fli 1 (2005) (7)
Cutaneous type adult T‐cell leukaemia/lymphoma successfully treated with narrowband ultraviolet B phototherapy (2012) (7)
S100A7 expression levels in coordination with interleukin‐8 indicate the clinical response to infliximab for psoriasis patients (2017) (7)
The stimulatory effects of PDGF and TGF-beta 1 on dermal fibroblast attachment. (1995) (7)
Case of blastic plasmacytoid dendritic cell neoplasm (2012) (7)
A case of systemic sclerosis with anticentromere, antitopoisomerase I, and anti-U1RNP antibodies. (1993) (7)
Wound, pressure ulcer and burn guidelines - 2: Guidelines for the diagnosis and treatment of pressure ulcers, second edition. (2018) (7)
Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation. (2005) (7)
Serum TARC/CCL17 levels are increased in dermatomyositis associated with interstitial lung disease. (2010) (7)
A Novel Protein Highly Expressed in Testis Is Overexpressed in Systemic Sclerosis Fibroblasts and Targeted by Autoantibodies 1 (2003) (7)
Nation-wide survey of advanced non-melanoma skin cancers treated at dermatology departments in Japan. (2018) (7)
Topical efinaconazole: A promising therapeutic medication for tinea unguium (2018) (7)
Establishment and gene expression analysis of disease-derived induced pluripotent stem cells of scleroderma. (2016) (6)
[A case of very late onset overlap syndrome of systemic sclerosis and systemic lupus erythematosus]. (2000) (6)
Subcutaneous cystic phaeohyphomycosis due to Pleurostomophora richardsiae (2017) (6)
Autoantibodies to the heat-shock protein hsp73 in localized scleroderma (1995) (6)
Diagnosis of nail psoriasis: evaluation of nail-derived microRNAs as potential novel biomarkers (2017) (6)
A case of anaplastic large cell lymphoma of skeletal muscle (2014) (6)
Localized Cutaneous Cryptococcosis: Summary of Reported Cases in Japan. (2016) (6)
Onychomycosis caused by Aspergillus subramanianii (2018) (6)
Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma. (2020) (6)
Non-small-cell Lung Cancer with Severe Skin Manifestations Related to Radiation Recall Dermatitis after Atezolizumab Treatment (2020) (6)
Clinical Evaluation of Moisturizers with Physiological Analysis of Stratum Corneum TARC and TSLP (2014) (6)
Transcriptional Regulation of the Human α2(I) Collagen Gene (1996) (6)
Platelet-rich plasma therapy is effective for the treatment of refractory skin ulcers in patients with systemic sclerosis (2015) (6)
Effect of topical immunotherapy with squaric acid dibutylester for alopecia areata in Japanese patients. (2019) (6)
Psoriasis guttata in association with hepatocellular carcinoma. (2003) (6)
A potential significance of circ_0024169 down regulation in angiosarcoma tissue. (2019) (6)
Angiogenin expression in the sera and skin of patients with rheumatic diseases. (2012) (5)
Increased CD27 expression in the skins and sera of patients with systemic sclerosis. (2020) (5)
Exome sequence analysis of Kaposiform hemangioendothelioma: identification of putative driver mutations* (2016) (5)
Subcutaneous cystic phaeohyphomycosis caused by Exophiala jeanselmei (2019) (5)
miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma (2020) (5)
Royal jelly regulates the proliferation of human dermal microvascular endothelial cells through the down-regulation of a photoaging-related microRNA. (2019) (5)
Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma (2015) (5)
Fosravuconazole to treat severe onychomycosis in the elderly (2020) (5)
Serum angiopoietin-like protein 3 concentrations in rheumatic diseases. (2012) (5)
Expression of aurora kinase A expression in dermatofibrosarcoma protuberans (2018) (5)
[Anti-inflammatory Effect of Sacran on Atopic Dermatitis]. (2018) (5)
Serum levels of manganese superoxide dismutase in patients with localized scleroderma (2004) (5)
Small bowel perforation due to indistinguishable metastasis of angiosarcoma: case report and brief literature review (2016) (5)
Elevated procollagen type I carboxyterminal propeptide production in cultured scleroderma fibroblasts. (1995) (5)
Wound, pressure ulcer and burn guidelines - 1: Guidelines for wounds in general, second edition. (2020) (5)
AT-rich Interaction Domain-containing Protein 3B is a New Tumour Marker for Melanoma. (2017) (5)
Non‐radioisotope method for diagnosing photosensitive genodermatoses and a new marker for xeroderma pigmentosum variant (2009) (5)
Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma (2021) (4)
Induced pluripotent stem cell-derived myeloid cells expressing OX40 ligand amplify antigen-specific T cells in advanced melanoma. (2020) (4)
Wound, pressure ulcer and burn guidelines – 6: Guidelines for the management of burns, second edition (2020) (4)
A mechanism of cooling hot tumors: Lactate attenuates inflammation in dendritic cells (2021) (4)
Hidradenocarcinoma showing prominent mucinous and squamous differentiation and associated pagetoid cells (2013) (4)
Infliximab improved the refractory cutaneous involvement in a patient with dermatomyositis (2019) (4)
The expression levels of thrombospondin-1 in dermatofibroma and dermatofibrosarcoma protuberans. (2011) (4)
Liquid biopsy-based analysis by ddPCR and CAPP-Seq in melanoma patients. (2021) (4)
Fungal Melanonychia: Ungual Phaeohyphomycosis caused by Botryosphaeria dothidea. (2017) (4)
Elevated circulating cell‐free DNA levels in autoimmune bullous diseases (2020) (4)
The growth of Vibrio vulnificus and the habitat of infected patients in Kumamoto. (2007) (4)
Immunoglobulin G4‐related disease in a psoriasis vulgaris patient treated with ustekinumab (2014) (4)
Serum levels of soluble carbonic anhydrase IX are decreased in patients with diffuse cutaneous systemic sclerosis compared to those with limited cutaneous systemic sclerosis. (2014) (4)
The expression of EpCAM in extramammary Paget's disease. (2019) (4)
Evaluation of usefulness of 3D views for clinical photography. (2011) (4)
p38 MAPK inhibitors in dermatology (2007) (4)
Serum concentrations of Flt-3 ligand in rheumatic diseases. (2015) (3)
RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis. (2017) (3)
Dabrafenib and trametinib combination therapy safely performed in a patient with metastatic melanoma after severe liver toxicity due to vemurafenib (2018) (3)
Case of metastatic extramammary Paget's disease treated with trastuzumab‐biosimilar monotherapy after S‐1 and docetaxel combination chemotherapy (2020) (3)
Rosai-Dorfman disease presenting as large pigmented indurated plaques. (2003) (3)
Wound, pressure ulcer and burn guidelines – 4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers (2020) (3)
Amelanotic malignant melanoma where primary lesion was discovered 5 years after metastasis in the lymph node (2010) (3)
Epidermal growth factor up-regulates transforming growth factor-beta receptor type II in human dermal fibroblasts via p38 mitogen-activated protein kinase pathway. (2007) (3)
Initial predictors of skin thickness progression in patients with diffuse cutaneous systemic sclerosis: Results from a multicentre prospective cohort in Japan (2020) (3)
Clinical significance of antinuclear matrix antibody in serum from patients with anti-U1RNP antibody (2000) (3)
Square‐shaped scleredema in the back: probably induced by mechanical stress (2005) (3)
Elevated serum levels of manganese superoxide dismutase in patients with eosinophilic fasciitis (2003) (3)
Bromoderma in a pituitary adenoma patient treated with bromocriptine (2017) (3)
Successful treatment of skin fistulas in systemic sclerosis patients with the combination of topical negative pressure therapy and split-thickness skin grafting (2013) (3)
CEA (Carcinoembryonic Antigen) and CEACAM6 (CEA-Related Cell Adhesion Molecul 6) are Expressed in Psoriasis Vulgaris (2013) (3)
Serum anti-p53 autoantibodies in angiosarcoma. (2020) (3)
Recurrent Fusion Gene ADCK4-NUMBL in Cutaneous Squamous Cell Carcinoma Mediates Cell Proliferation. (2019) (3)
A new disorder in UV-induced skin cancer with defective DNA repair distinct from xeroderma pigmentosum or Cockayne syndrome. (2008) (3)
Existence of Staphylococcus aureus correlates with the progression of extramammary Paget’s disease: potential involvement of interleukin-17 and M2-like macrophage polarization (2021) (3)
Exosome expression in the skin and sera of systemic sclerosis patients, and its possible therapeutic application against skin ulcer (2016) (3)
CXCL17-mediated downregulation of type I collagen via MMP1 and miR-29 in skin fibroblasts possibly contributes to the fibrosis in systemic sclerosis. (2020) (3)
Serum epidermal growth factor receptor levels in patients with malignant melanoma (2013) (3)
Decreased IL-20 expression in scleroderma skin contributes to cutaneous fibrosis (2016) (3)
Ungual aspergillosis successfully treated with topical efinaconazole (2017) (3)
Do scleroderma patients look young?: Evaluation by using facial imaging system. (2017) (3)
RADIATION-INDUCED EPIDERMAL DAMAGE BY EXPRESSION OF HEAT SHOCK PROTEIN 70 * (2009) (3)
Fibroblasts Signaling in Scleroderma b Autocrine TGF-Contributes to the Establishment of 3 b v a Increased Expression of Integrin (2005) (3)
1 SUPPRESSION OF MELANIN PRODUCTION BY EXPRESSION OF HSP 70 * (2010) (3)
A novel COL1A1 exon 14/PDGFB fusion gene in dermatofibrosarcoma protuberans. (2010) (2)
Prognostic Signi fi cance of CD 169 þ Lymph Node Sinus Macrophages in Patients with Malignant Melanoma (2015) (2)
Papulonecrotic tuberculid after Bacillus Calmette–Guérin (BCG) vaccination with lung infiltration that mimics disseminated BCG infection (2019) (2)
Circulating miR-1423 p levels in patients with systemic sclerosis (2011) (2)
A Case of Lichen Sclerosus et Atrophicus with Marked Fibrosis in the Dermis: Analysis of Fibrogenetic Cytokines by Reverse Transcriptase‐Polymerase Chain Reaction (2004) (2)
Clinical Significance of Serum Vascular Endothelial-Cadherin Levels in Inflammatory Skin Diseases (2014) (2)
microRNA level is raised in the hair shafts of patients with dematomyositis in comparison with normal subjects and patients with scleroderma (2016) (2)
Eosinophilic Pustular Folliculitis with a Butterfly Rash-Like Distribution (2004) (2)
Multiple subcutaneous Candida abscesses on the palm and finger in an immunocompetent patient (2017) (2)
Anti‐p53 antibodies in patients with systemic sclerosis (2007) (2)
Retrospective study of COL1A1‐PDGFB fusion gene‐positive dermatofibrosarcoma protuberans in Kumamoto University (2020) (2)
Natural course of epidermolysis bullosa simplex with mottled pigmentation in a Japanese family with the p.P25L mutation in KRT5 (2019) (2)
Onychomycosis caused by Trichosporon cacaoliposimilis (2020) (2)
Genomic mutational profiling of circulating tumour DNA in metastatic angiosarcoma (2020) (2)
Impact of a new simplified disability scoring system for adult patients with localized scleroderma (2018) (2)
Retrospective study of clinical and laboratory features in Japanese scleroderma patients with cardiac involvement. (2009) (2)
BATF2 expression as a novel marker for invasive phenotype in malignant melanoma (2020) (2)
The down-regulation of miR-223 contributes to the formation of Gottron's eruption via the induction of PKCɛ in dermatomyositis (2013) (2)
A case of scleroderma associated with interstitial neutrophilic granulomatous reaction (2019) (2)
Clinical course of Japanese patients with early systemic sclerosis: A multicenter, prospective, observational study (2020) (2)
[The pathogenesis of fibrosis in scleroderma]. (2003) (2)
Using the smallest skin excision without dog-ear formations: utilizing histopathology on the face. (2008) (1)
Serum levels of genomic DNA of α1(I) collagen are elevated in scleroderma patients (2017) (1)
Dyskeratosis congenita associated with congenital hypothyroidism (2018) (1)
3325 Safety and efficacy of Pembrolizumab (MK-3475) for Japanese patients (pts) with advanced melanoma: Preliminary results from KEYNOTE-041 Phase 1b study (2015) (1)
Brain abscess in an angiosarcoma patient during a disease-free interval. (2019) (1)
Severe bacterial sepsis results in delayed diagnosis of tuberculous lymphadenitis in a rheumatoid arthritis patient treated with adalimumab. (2018) (1)
A case of pemphigus vulgaris that transitioned from pemphigus foliaceus (2008) (1)
Early phase dynamics of traceable mCherry fluorescent protein‐carrying HIV‐1 infection in human peripheral blood mononuclear cells‐transplanted NOD/SCID/Jak3‐/‐ mice (2017) (1)
KERATINOCYTE APOPTOSIS ON TYPE I COLLAGEN GEL CAUSED BY A LACK OF LAMININ 5 AND 10/11 DEPOSITION (2002) (1)
First Aid for Skin Tears by Mini Patch Grafting from the Flap Edge. (2018) (1)
[A female case of hyper-IgM immunodeficiency syndrome with uncommon skin manifestations]. (2004) (1)
Basic (PS01–PS58) (2012) (1)
Overexpression of MUC16 (CA125) in extramammary Paget's disease. (2020) (1)
Transcriptional regulation of type I collagen gene (2001) (1)
Ungual hyalohyphomycosis caused by Fusarium proliferatum successfully treated with fosravuconazole (2020) (1)
The pathogenesis of scleroderma: The role of autocrine TGF-β signaling (2004) (1)
The Lesional Skin of Linear IgA Bullous Dermatosis Expresses Growth‐Regulated Peptide (GRO)‐α (2004) (1)
A Case of Lichen Nitidus Induced by Amlodipine Besylate (2018) (1)
Interleukin-23 signaling contributes to the increased collagen production in scleroderma fibroblasts (2013) (1)
Case of pigmented lipofibromatosis in a 27‐year‐old woman (2018) (1)
Serious disseminated intravascular coagulation associated with combination therapy of nivolumab and ipilimumab in advanced melanoma (2020) (1)
Characteristics of Japanese patients with eosinophilic fasciitis: A brief multicenter study (2020) (1)
Psoriasis vulgaris associated with superior vena cava syndrome due to lung cancer metastasis (2007) (1)
Excessive expression of type I collagen in systemic and localized scleroderma is caused by the down-regulation of microRNA let-7a (2013) (1)
Constitutive phosphorylated Smad3 interacts with Sp1 and p300/CBP in scleroderma fibroblasts (2004) (1)
Sweet's syndrome with laryngoparalysis due to laryngitis (2018) (1)
Bullous dermatosis on legs of elderly: A new clinical entity? (2017) (1)
Successful treatment of skin fistulas in systemic sclerosis patients with the combination of topical negative pressure therapy and split-thickness skin grafting (2013) (1)
Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells. (2021) (1)
Expression of Let-7 Family microRNAs in Skin Correlates Negatively with Severity of Pulmonary Hypertension in Patients with Systemic Scleroderma (2015) (1)
Nivolumab‐induced colitis in a patient with malignant melanoma: A case report and immunological analysis (2019) (1)
A successful case of lupus myelitis treated with intravenous pulse methylprednisolone and pulse cyclophosphamide therapy. (2020) (1)
Efficacy and safety of adalimumab in Japanese patients with psoriatic arthritis and inadequate response to non-steroidal anti-inflammatory drugs (NSAIDs): A prospective, observational study (2020) (1)
Overexpression of Janus kinase 2 protein in extramammary Paget's disease. (2021) (1)
Clinical Usefulness of Immunostaining with CEA in Distinction between Malignant Melanoma and Spitz Nevus (2016) (1)
Clinical Usefulness of Immunostaining with CEA in Distinction between Malignant Melanoma and Spitz Nevus (2016) (1)
Case of cutaneous myoepithelioma managed with surgical resection without recurrence for 4 years (2019) (1)
Serum levels of leptin receptor in patients with systemic sclerosis. (2013) (1)
Effect of adalimumab on axial manifestations in Japanese patients with psoriatic arthritis: a 24 week prospective, observational study. (2021) (1)
A case of overlap syndrome (scleroderma and polymyositis) associated with the development of sudden chest pain due to myocardial damage. (2019) (1)
Cutaneous spindle cell adenolipoma on the nose: A rare variant of lipoma (2017) (1)
A case of psoriasis accompanied by arthritis after delivery. (2014) (1)
In Memoriam / Announcements (1999) (1)
Pyodermatitis vegetans associated with multiple myeloma (2013) (1)
Status of microsatellite stability in angiosarcoma: Angiosarcoma is a microsatellite stable tumor (2021) (1)
Simple and effective modification of the axial frontonasal flap to prevent flap distortion (2018) (1)
Treatment for recurrent and metastatic melanoma (2006) (1)
Immune cell therapy against disseminated melanoma by utilizing induced pluripotent stem cell-derived myeloid cell lines producing interferon-beta or interleukin-15/interleukin-15 receptor alpha. (2021) (1)
Intratumor dihydropyrimidine dehydrogenase mRNA expression levels are decreased in extramammary Paget's disease. (2017) (1)
A Case of 3-mm-Sized Superficial Spreading Melanoma in Situ (1993) (0)
467 Immunotherapy with 4-1BBL-expressing iPScell-derived myeloid lines (2019) (0)
Putative driver mutations of Kaposiform hemangioendothelioma detected by exome sequence analysis (2017) (0)
Single-Nucleotide Polymorphisms and Haplotypes in the VEGF Receptor 3 Gene and the Haplotype GC in the VEGFA Gene Are Associated with Psoriasis in Koreans (2010) (0)
Altered expression and function of exosomes in scleroderma dermal fibroblasts (2016) (0)
Breakage of Growth Hormone Needle in Subcutaneous Tissue of a Six-Year-Old Child's Buttock (2017) (0)
Subcutaneous cystic phaeohyphomycosis caused by Phaeoacremonium minimum (2021) (0)
[Cancer immunotherapy by utilizing dedritic cells derived from pluripotent stem cells]. (2011) (0)
A case of systemic sclerosis with interstitial lung disease successfully treated with intravenous cyclophosphamide pulse therapy and oral azathioprine (2016) (0)
A case of bloch-sulzberger syndrome (2016) (0)
Fluorescence in situ hybridization for diagnosis of malignant melanoma using RREB1, MYB, Cep6, and CCND1 probes in Japanese patients (2017) (0)
Ungual hyalohyphomycosis caused by Fusarium cugenangense (2020) (0)
Corrigendum: HPGCD Outperforms HPBCD as a Potential Treatment for Niemann‐Pick Disease Type C During Disease Modeling with iPS Cells (2015) (0)
Aurora kinase A protein expression in dermatofibrosarcoma protuberans. (2016) (0)
and Scleroderma Fibroblasts 2(I) Collagen Gene Expression in Normal a Phosphatidylinositol 3-Kinase Is Involved in (2004) (0)
A case of recurrent extramammary Paget’s disease treated with several chemotherapies (2019) (0)
Palm eccrine porocarcinoma with deep cubital lymph nodes identified as sentinel lymph nodes (2007) (0)
microRNA150 contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrinβ3 (2013) (0)
Chronic sun exposure-related fusion oncogenes EGFR-PPARGC1A in cutaneous squamous cell carcinoma (2017) (0)
Overexpression of heat shock protein 90 as a potential therapeutic target for angiosarcoma (2017) (0)
Psoriasis arthropathica accompanied with severe bone deformity (1993) (0)
Clinical significance of cobblestone appearance on the skin of patients with systemic sclerosis (2012) (0)
dysregulated interleukin-37 signaling contributes to the increased collagen production in scleroderma skin : Mo-p11-8 (2017) (0)
Serum levels of desmoglein‐1 DNA copies in cell‐free DNA of patients with pemphigus (2020) (0)
Reducing regional lymph node dissections in skin cancers (2007) (0)
The effect of IL‐17 on the extracellular matrix expression in dermal fibroblasts (2013) (0)
Aesthetic reconstruction of defects in the lateral side wall of the nose using a local V‐Y flap (2014) (0)
Constitutive Thrombospondin-1 Overexpression Contributes to the Autocrine TGF-β Signaling in Cultured Scleroderma Fibroblasts (2006) (0)
A Follow-up Study of Skin Thickness in a Patient with Systemic Sclerosis Using an Ultrasound Apparatus. (1996) (0)
Fibroblasts Expression in Scleroderma Dermal Constitutive Upregulated Type I Collagen MicroRNA-196 a Contributes to the Mediated Downregulation of − β (2012) (0)
Two cases with cutaneous melanoma who experienced acute myocardial infarction related to chemotherapy (2006) (0)
Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle (2018) (0)
Fulminant Type 1 Diabetes Mellitus Associated with Drug Induced Hypersensitivity Syndrome by Zonisamide (Excegran) (2008) (0)
1241 Pretreatment serum CTLA-4 is a potential biomarker of a risk of immune-related adverse events in metastatic melanoma (2018) (0)
articleCharacterization of monocyte / macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis (2015) (0)
Genomic landscape of circulating tumour DNA in metastatic extramammary Paget’s disease (2021) (0)
Effect of endothelial cell-derived endothelin-1 on wound healing (2015) (0)
Drug eruption induced by imatinib mesylate (Glivec (2007) (0)
Cell division cycle associated gene 1 as a new therapeutic target for melanoma (2016) (0)
Two cases of mixed connective tissue disease initially diagnosed as rheumatoid arthritis (1993) (0)
A simple and effective reconstructive technique for repairing defects of the upper lip using a hatchet flap (2014) (0)
A case of primary penile malignant melanoma (2007) (0)
Contents Vol. 227, 2013 (2014) (0)
Upregulated Tenascin-C Expression in Stroma around Basal Cell Carcinoma;Induction by Interleukin-13 in Human Dermal Fibroblasts via PI3-K/Akt and PKC pathway (2003) (0)
Fibroblasts and Targeted by Autoantibodies Overexpressed in Systemic Sclerosis A Novel Protein Highly Expressed in Testis Is (2003) (0)
Methyl-CpG binding domain protein 3: a new diagnostic marker and potential therapeutic target of melanoma. (2020) (0)
A Male Case of Systemic Sclerosis with Anti Th/To Antibody (2001) (0)
Clinical aspects of cutaneous fibrotic diseases and molecular mechanism of skin fibrosis (the last part) - Molecular mechanism of skin fibrosis (2009) (0)
Phenothrin Lotion Treatment in 5 Cases of 2 or 3 Year Old Children with Scabies (2017) (0)
Expression in Scleroderma Fibroblasts Contributes to the Increased Collagen Impaired IL-17 Signaling Pathway (2012) (0)
Amicrobial Pustulosis Associated with Autoimmune Disease の 1 例 (2015) (0)
270 A novel small compound HPH-15 antagonizes TGF-β/Smad signaling and ameliorates experimental skin fibrosis (2017) (0)
Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors (2014) (0)
402 Serum levels of genomic DNA of α1(I) collagen are detectable and elevated in scleroderma patients (2017) (0)
463 Heat shock protein 90 is a novel therapeutic target for angiosarcoma (2016) (0)
Identification of disease-specific molecules in the skin of dermatomyositis and lupus erythematosus by proteomics analysis using LC–MS/MS (2016) (0)
Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK (2012) (0)
Clinical aspects of cutaneous fibrotic diseases and molecular mechanism of skin fibrosis (the second part) - Localized scleroderma, lupus erythematosus profundus, lichen sclerosis et atrophicus, sclerosing panniculitis, and keloid/hypertrophic scar (2009) (0)
470 Endoglin enhances the progression of angiosarcoma through the regulation of non-Smad TGF-β signaling (2019) (0)
THU0006 Trans-ethnic meta-analysis of genome-wide association studies identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis (2017) (0)
A case of malignant proliferating trichilemmal cyst (MPTC) presenting as a cancer en cuirasse (2011) (0)
Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle (2017) (0)
Symptomless Pulmonary Cryptococcosis in a Psoriatic Arthritis Patient during Infliximab Therapy (2016) (0)
A novel small compound that antagonizes TGF-β/Smad signaling ameliorates bleomycin-induced skin fibrosis (2017) (0)
A case of malignant melanoma on the anal lesion (2010) (0)
456 Secreted Protein Acidic and Rich in Cysteine, a new biomarker of localized scleroderma (2017) (0)
470 Putative driver mutations of Kaposiform hemangioendothelioma detected by exome sequence analysis (2016) (0)
Geographical Flushing of the Children's Face: A New Clinical Entity? (2013) (0)
Single administration of avelumab induced a complete response in thyroid transcription factor 1‐positive combined Merkel cell carcinoma (2020) (0)
A case of malignant melanoma observed to an eye skin albinism patient with various complications. (1992) (0)
IL-13 UPREGULATES TENASCIN SYNTHESIS IN DERMAL FIBROBLASTS (2002) (0)
Up-regulation of miR-18a contributes to the epidermal necrolysis in severe drug eruptions (2013) (0)
Protein Kinase-Dependent Pathway Dermal Fibroblasts Via a Mitogen-Activated Oncostatin (2000) (0)
Anorectal malignant melanoma with extensive intraepithelial extension: report of a case (2015) (0)
453 T cell receptor repertoire analysis in the melanoma patient with myasthenic crisis and polymyositis induced by nivolumab (2016) (0)
AT-rich interaction domain-containing protein 3B has a potential to be a new stem cell marker of melanoma (2016) (0)
CCR9 expression levels in psoriatic skin negatively correlates with clinical outcome to infliximab (2017) (0)
546 Immune biomarkers to predict response of nivolumab, intratumoral gene expression and T cell receptor repertoire analysis (2017) (0)
[Systemic sclerosis]. (2019) (0)
A Case of Obstructive Arteriosclerosis with Successful Autologous Peripheral Blood Mononuclear Cell Transplantation for Intractable Cutaneous Ulcers (2019) (0)
Spontaneous regression of genital warts at untreated sites following electrocoagulation treatment for lesions at the other sites (2019) (0)
DNA Damage and Repair Angiopoietin-like Protein 2 Accelerates Carcinogenesis by Activating Chronic In fl ammation and Oxidative Stress (2014) (0)
Increased CCL22 expression levels in psoriatic skin predict the good response to infliximab (2016) (0)
Interdigital Hyalohyphomycosis Caused by Members of the Fusarium solani Species Complex. (2019) (0)
The contribution of microRNA let-7a to the excessive production of type I collagen in systemic sclerosis (2017) (0)
Successful prednisolone treatment of peripartum Behçet disease associated with HLA‐A26 (2020) (0)
SclerodermaType I Collagen in Systemic and Localized Contributes to the Excessive Expression of The Downregulation of microRNA let-7a (2013) (0)
Erratum: HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C during Disease Modeling with iPS Cells (Stem Cells (2015) 33:4 (1075) DOI: 10.1002/stem.1917) (2015) (0)
Search of the skin constancy maintenance factor using the proteomics method (2016) (0)
479 Verification of the AT-rich interaction domain-containing protein 3B as a potent stem cell marker of melanoma comparing with CD271 (2016) (0)
bFGF stimulates the proliferation of cultured human dermal fibroblasts (2009) (0)
Successful treatment of occult pancreatic melanoma using BRAF/MEK inhibitors (2019) (0)
Abstract 1276: CD169-positive sinus macrophages in regional lymph nodes are associated with better survival in patients with malignant melanoma (2015) (0)
Lupus erythematosus profundus: Clinical and pathological features of 23 cases (2013) (0)
371 The antitumor effect of basic leucine zipper transcription factor ATF-like 2 through IL-12 p40 upregulation (2017) (0)
Decreased adiponectin levels in the patients with diffuse cutaneous systemic sclerosis (2013) (0)
Clinical significance of CD169-positive lymph node macrophages in human malignant tumors. (2014) (0)
The mechanisms involved in the bFGF-mediated proliferative activation of cultured human dermal fibroblasts (2012) (0)
188 The novel diagnostic system to distinguish melanoma from nevus using droplet digital PCR (2018) (0)
539 Immunotherapy against metastatic melanoma with iPS cell-derived myeloid cell lines producing IFN-β or IL-15 (2017) (0)
Clinicopathological demographics of malignant melanoma of the vulva and vagina in Japan: Japanese Gynecologic Oncology Group (JGOG)/Japanese Skin Cancer Society (JSCS)—Intergroup Study. (2020) (0)
Two cases of anaphylactoid purpura that led to the diagnosis of malignancy (2006) (0)
Hair shaft miRNA-221 levels as a new tumor marker of melanoma (2016) (0)
[Treatment of skin ulcers in collagen vascular diseases]. (2008) (0)
A Case of Atopic Dermatitis with Infective Endocarditis (2008) (0)
Abstract 3213: Combination of anti-IL-6 and anti-PD-L1 antibodies synergistically reinvigorates cancer immunity by activating both CTL and Th1 cells in mice (2019) (0)
124 Analysis of the prevalence of fusion oncogenes in cutaneous angiosarcoma (2017) (0)
667 A novel TGF-beta/Smad signaling inhibitor ameliorates bleomycin-induced skin fibrosis (2017) (0)
Raltegravir blocks the infectivity of red‐fluorescent‐protein (mCherry)‐labeled HIV‐1JR‐FL in the setting of post‐exposure prophylaxis in NOD/SCID/Jak3−/− mice transplanted with human PBMCs (2018) (0)
Serum leptin receptor as a tumor marker of melanoma (2016) (0)
Clinical aspects of cutaneous fibrotic diseases and molecular mechanism of skin fibrosis (the first part) - Systemic sclerosis (2009) (0)

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What Schools Are Affiliated With Hironobu Ihn?

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