Hiroshi Mori
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Hiroshi Moribiology Degrees
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Philosophy Biology
Hiroshi Mori's Degrees
- PhD Neuroscience University of Tokyo
- Doctorate Medicine University of Tokyo
Why Is Hiroshi Mori Influential?
(Suggest an Edit or Addition)Hiroshi Mori's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. (2006) (2228)
- Ubiquitin is a component of paired helical filaments in Alzheimer's disease. (1987) (703)
- Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013) (661)
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) (487)
- Mass spectrometry of purified amyloid beta protein in Alzheimer's disease. (1992) (456)
- A new amyloid β variant favoring oligomerization in Alzheimer's‐type dementia (2008) (398)
- Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome (2002) (360)
- A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo (2010) (359)
- Amyloid β-protein deposition in tissues other than brain in Alzheimer's disease (1989) (332)
- Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography (2007) (293)
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease (2020) (252)
- The car☐yl third of tau is tightly bound to paired helical filaments (1988) (229)
- TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. (2007) (212)
- Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo (2011) (199)
- Lewy bodies are ubiquitinated (1988) (192)
- Aluminum Promotes the Aggregation of Alzheimer′s Amyloid β-Protein in Vitro (1994) (184)
- Human neprilysin is capable of degrading amyloid β peptide not only in the monomeric form but also the pathological oligomeric form (2003) (181)
- Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for α-synuclein (1998) (180)
- Isoaspartate formation and neurodegeneration in Alzheimer's disease. (2000) (175)
- Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy (2006) (171)
- High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types. (2009) (163)
- Subcellular Distribution and Turnover of Presenilins in Transfected Cells* (1998) (148)
- Rifampicin prevents the aggregation and neurotoxicity of amyloid beta protein in vitro. (1994) (148)
- Racemization of Asp23 residue affects the aggregation properties of Alzheimer amyloid beta protein analogues. (1994) (144)
- Isoforms changes of tau protein during development in various species. (2003) (136)
- Amyloid β protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease (1997) (132)
- Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. (1994) (129)
- In Vivo Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders (2011) (123)
- Association between severity of alcoholism and the A1 allele of the dopamine D2 receptor gene TaqI A RFLP in Japanese (1993) (120)
- Ubiquitin is a component of paired helical filaments in Alzheimerʼs disease (1987) (119)
- The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. (2009) (116)
- Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study. (1999) (110)
- Presenilin-1 Mutations Reduce Cytoskeletal Association, Deregulate Neurite Growth, and Potentiate Neuronal Dystrophy and Tau Phosphorylation (2001) (110)
- Aβ‐peptide length aid apolipoprotein E genotype in Alzheimer's disease (1996) (109)
- Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′s disease (1994) (103)
- Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease. (1989) (103)
- β-Amyloid (Aβ) Deposition in the Brains of Aged Orangutans (1997) (100)
- Occurrence of the diffuse amyloid β‐protein (Aβ) deposits with numerous Aβ‐containing glial cells in the cerebral cortex of patients with Alzheimer's disease (1999) (97)
- Aβ 40 is a major form of β-amyloid in nonhuman primates (1996) (96)
- Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers. (2016) (94)
- Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains. (2006) (90)
- Intraneuronal amyloid-beta oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo (2011) (90)
- Aβ1–40 but not Aβ1–42 levels in cortex correlate with apolipoprotein E ϵ4 allele dosage in sporadic Alzheimer's disease (1997) (84)
- Apolipoprotein E allele–dependent antioxidant activity in brains with Alzheimer’s disease (2000) (77)
- Aβ−42 deposition precedes other changes in PS-1 Alzheimer's disease (1998) (77)
- Tau‐4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/ knockout mice (2007) (76)
- Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis. (1989) (76)
- Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis (1990) (74)
- Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein (1996) (74)
- Novel chalcones as probes for in vivo imaging of beta-amyloid plaques in Alzheimer's brains. (2007) (72)
- Radioiodinated Flavones for in Vivo Imaging of β-Amyloid Plaques in the Brain (2005) (71)
- Amyloid β protein 1–42/43 (Aβ 1–42/43) in cerebellar diffuse plaques: enzyme-linked immunosorbent assay and immunocytochemical study (1995) (70)
- Amyloid Beta Peptide‐Induced Cerebral Neuronal Loss Is Mediated By Caspase‐3 In Vivo (2004) (69)
- Synthesis, aggregation, and neurotoxicity of the Alzheimer's Abeta1-42 amyloid peptide and its isoaspartyl isomers. (1999) (67)
- Contrasting Role of Presenilin-1 and Presenilin-2 in Neuronal Differentiation In Vitro (1999) (66)
- Caspase-3-deficiency induces hyperplasia of supporting cells and degeneration of sensory cells resulting in the hearing loss (2001) (66)
- Tau protein is a potential biological marker for normal pressure hydrocephalus (2000) (64)
- Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimer's disease. (1999) (63)
- Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice. (2012) (63)
- Amyloid beta protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease. (1997) (62)
- Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains. (2011) (61)
- Aurones serve as probes of β-amyloid plaques in Alzheimer’s disease (2007) (59)
- Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation (2005) (57)
- Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice (2014) (57)
- Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus (2007) (57)
- A beta40 is a major form of beta-amyloid in nonhuman primates. (1996) (55)
- Mutation (D472Y) in the type 3 repeat domain of cartilage oligomeric matrix protein affects its early vesicle trafficking in endoplasmic reticulum and induces apoptosis. (2003) (54)
- Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons (2015) (51)
- Modified Amyloid β Protein Ending at 42 or 40 with Different Solubility Accumulates in the Brain of Alzheimer′s Disease (1995) (50)
- Deposition of beta-amyloid subtypes 40 and 42 differentiates dementia with Lewy bodies from Alzheimer disease. (1999) (49)
- Racemization: its biological significance on neuropathogenesis of Alzheimer's disease. (1994) (49)
- Increased Aβ 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 gene (1997) (47)
- A subset of senile dementia with high incidence of the apolipoprotein E ϵ2 allele (1997) (47)
- Immunocytochemical and ultrastructural study of Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis (2004) (45)
- A distinct form of tau is selectively incorporated into Alzheimer's paired helical filaments. (1989) (45)
- Naturally occurring and experimentally induced beta-amyloid deposits in the brains of marmosets (Callithrix jacchus). (2000) (45)
- Increased CSF tau protein in corticobasal degeneration (1997) (44)
- Structure-activity relationship of chalcones and related derivatives as ligands for detecting of beta-amyloid plaques in the brain. (2007) (44)
- Identification and characterization of presenilin I-467, I-463 and I-374 (1996) (44)
- Missense point mutations of tau to segregate with FTDP‐17 exhibit site‐specific effects on microtubule structure in COS cells: A novel action of R406W mutation (2000) (43)
- beta-Amyloid (A beta) deposition in the brains of aged orangutans. (1997) (43)
- A novel presenilin-1 mutation (Leu85Pro) in early-onset Alzheimer disease with spastic paraparesis. (2004) (43)
- Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice (2015) (43)
- Proteomic analysis of the hippocampus in Alzheimer's disease model mice by using two-dimensional fluorescence difference in gel electrophoresis (2013) (42)
- Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. (2021) (41)
- The tau mutation (val337met) disrupts cytoskeletal networks of microtubules. (1999) (38)
- Pattern of tau isoforms expression during development in vivo (2009) (38)
- Plasma levels of amyloid beta 40 and 42 are independent from ApoE genotype and mental retardation in Down syndrome. (2000) (38)
- Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin‐1‐deficient mice (2002) (36)
- Characterization of antisera to paired helical filaments and tau. Implication for the extent of tau tightly bound to paired helical filaments. (1990) (36)
- Proteolytic processing of presenilin‐1 (PS‐1) is not associated with Alzheimer's disease with or without PS‐1 mutations (1997) (36)
- Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production. (2004) (35)
- Carboxyl end-specific monoclonal antibodies to amyloid β protein (Aβ) subtypes (Aβ40 and Aβ42(43)) differentiate Aβ in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys (1995) (35)
- Absence of synaptophysin near cortical neurons containing oligomer Aβ in Alzheimer's disease brain (2006) (35)
- Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains (2011) (34)
- Clinical Course of Patients with Familial Early-Onset Alzheimer’s Disease Potentially Lacking Senile Plaques Bearing the E693Δ Mutation in Amyloid Precursor Protein (2011) (34)
- Platelet 3H-paroxetine binding in control subjects and depressed patients: Relationship to serotonin uptake and age (1994) (34)
- Naturally occurring and experimentally induced β-amyloid deposits in the brains of marmosets (Callithrix jacchus) (2000) (33)
- Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes. (2003) (33)
- Inverse correlation between amyloid precursor protein and synaptic plasticity in transgenic mice (2007) (33)
- α-Synuclein aggregation in pathological aging and Alzheimer's disease: The impact of ß-amyloid plaque level (2005) (32)
- Abnormal cytoskeletal pathology peculiar to corticobasal degeneration is different from that of Alzheimer's disease or progressive supranuclear palsy (2004) (32)
- Aluminum promotes the aggregation of Alzheimer's amyloid beta-protein in vitro. (1994) (31)
- Amyloid-&bgr; E22Δ variant induces synaptic alteration in mouse hippocampal slices (2008) (31)
- Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease. (1996) (30)
- Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. (2019) (30)
- Embryonic genes expressed in Alzheimer's disease brains (1996) (30)
- Neurodegenerative disorder FTDP-17-related tau intron 10 +16C → T mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice. (2013) (29)
- Abeta-42 deposition precedes other changes in PS-1 Alzheimer's disease. (1998) (29)
- The amino-terminally truncated forms of amyloid β-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients (1996) (29)
- Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease. (1994) (29)
- Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of βAPP in neuronal cells (2005) (28)
- Ubiquitinated αB-crystallin in glial cytoplasmic inclusions from the brain of a patient with multiple system atrophy (1995) (28)
- Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner (2017) (26)
- Sigma receptors in schizophrenic cerebral cortices (1992) (26)
- Mutant presenilin (A260V) affects Rab8 in PC12D cell (2004) (26)
- A subset of senile dementia with high incidence of the apolipoprotein E epsilon2 allele. (1997) (25)
- Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease (2021) (25)
- Protein l-isoaspartyl methyltransferase: developmentally redulated gene expression and protein localization in the central nervous system of aged rat (1995) (25)
- Antibodies to amyloid β protein (Aβ) crossreact with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (1996) (24)
- Glial tau-positive structures lack the sequence encoded by exon 3 of the tau protein gene (1997) (24)
- Triple Immunofluorolabeling with Two Rabbit Polyclonal Antibodies and a Mouse Monoclonal Antibody Allowing Three-dimensional Analysis of Cotton Wool Plaques in Alzheimer Disease (2003) (24)
- A high incidence of apolipoprotein E ε4 allele in middle-aged non-demented subjects with cerebral amyloid β protein deposits (1999) (23)
- Molecular pathogenesis of apolipoprotein E-mediated amyloidosis in late-onset Alzheimer’s disease (1999) (23)
- Amyloid-β-protein isoforms in brain of subjects with PS1-linked, βAPP-linked and sporadic Alzheimer disease (1998) (23)
- Seizures as an early symptom of autosomal dominant Alzheimer's disease (2019) (23)
- Zinc enhances synthesis of presenilin 1 in mouse primary cortical culture. (2001) (22)
- Protein disulfide isomerase P5-immunopositive inclusions in patients with Alzheimer's disease. (2013) (22)
- Sequence of Alzheimer disease biomarker changes in cognitively normal adults (2020) (22)
- Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease. (2005) (21)
- Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease. (1997) (21)
- Proteomic analysis of the brain tissues from a transgenic mouse model of amyloid β oligomers (2012) (21)
- Distinguishable effects of Presenilin-1 and APP717 mutations on amyloid plaque deposition (2001) (21)
- Alpha-Synuclein aggregation in pathological aging and Alzheimer's disease: the impact of beta-amyloid plaque level. (2005) (20)
- Regulation of cholesterol efflux by amyloid β secretion (2010) (20)
- Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer’s disease: analysis of Osaka mutation-knockin mice (2017) (19)
- Neuronal expression of αB crystallin in cerebral infarction (2003) (19)
- Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons (2017) (19)
- The Syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of {beta}-amyloid precursor protein. (2009) (18)
- Pittsburgh Compound B-Negative Dementia—A Possibility of Misdiagnosis of Patients With Non-Alzheimer Disease-Type Dementia as Having AD (2011) (18)
- Increased GADD34 in oligodendrocytes in Alzheimer’s disease (2015) (18)
- Chrysamine G and its derivative reduce amyloid β-induced neurotoxicity in mice (2002) (18)
- Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study (2021) (17)
- Lack of amyloid plaque formation in the central nervous system of a patient with Werner syndrome (2003) (17)
- Molecular interactions between presenilin and calpain: inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain. (2000) (17)
- Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study (2022) (17)
- Cerebral vascular accumulation of Dutch‐type Aβ42, but not wild‐type Aβ42, in hereditary cerebral hemorrhage with amyloidosis, Dutch type (2007) (15)
- [Alzheimer's Disease Cooperative Study (ADCS)]. (2014) (15)
- The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol‐mediated intracellular amyloid β toxicity via its impaired cholesterol efflux (2013) (14)
- DCP-LA neutralizes mutant amyloid β peptide-induced impairment of long-term potentiation and spatial learning (2010) (14)
- Abnormal gel-electrophoretic behavior of presenilin 1 and it's fragment. (1996) (14)
- Clinical features of Pittsburgh compound-B–negative dementia (2012) (13)
- E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity (2010) (13)
- Ubiquitinated alpha B-crystallin in glial cytoplasmic inclusions from the brain of a patient with multiple system atrophy. (1995) (13)
- A second pedigree with amyloid-less familial Alzheimer's disease harboring an identical mutation in the amyloid precursor protein gene (E693delta). (2015) (12)
- Characterization of amyloid beta protein species in cerebral amyloid angiopathy of a squirrel monkey by immunocytochemistry and enzyme-linked immunosorbent assay. (1997) (12)
- Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease (2022) (12)
- Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease (2021) (12)
- A high incidence of apolipoprotein E epsilon4 allele in middle-aged non-demented subjects with cerebral amyloid beta protein deposits. (1999) (12)
- Carboxyl end-specific monoclonal antibodies to amyloid beta protein (A beta) subtypes (A beta 40 and A beta 42(43)) differentiate A beta in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys. (1995) (12)
- Cerebrovascular Amyloidosis and Dementia (2003) (11)
- Modeling autosomal dominant Alzheimer's disease with machine learning (2021) (11)
- Characterization of amyloid β protein species in cerebral amyloid angiopathy of a squirrel monkey by immunocytochemistry and enzyme-linked immunosorbent assay (1997) (11)
- Enhanced Aβ40 Deposition Was Associated with Increased Aβ42/43 in Cerebral Vasculature with Dutch‐Type Hereditary Cerebral Hemorrhage with Amyloidosis (HCHWA‐D) (2002) (11)
- Immunohistochemical localization of amyloid β-protein with amino-terminal aspartate in the cerebral cortex of patients with Alzheimer's disease (1999) (11)
- Neuronal expression of alphaB crystallin in cerebral infarction. (2003) (11)
- Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning (2020) (11)
- Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. (2005) (11)
- Untangling Alzheimer's disease from fibrous lesions of neurofibrillary tangles and senile plaques (2000) (10)
- Amyloid beta protein 1-42/43 (A beta 1-42/43) in cerebellar diffuse plaques: enzyme-linked immunosorbent assay and immunocytochemical study. (1995) (10)
- Presenilin 1 Cleavage is a Universal Event in Human Organs (1998) (10)
- Modified amyloid beta protein ending at 42 or 40 with different solubility accumulates in the brain of Alzheimer's disease. (1995) (10)
- The distributions of tau short and long isoforms fused with EGFP in cultured cells. (2004) (10)
- The Relationship Between Medial Temporal Lobe Atrophy and Cognitive Impairment in Patients With Dementia With Lewy Bodies (2015) (10)
- Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain (2018) (9)
- Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease (2017) (9)
- Antibodies to amyloid beta protein (A beta) crossreact with glyceraldehyde-3-phosphate dehydrogenase (GAPDH). (1996) (9)
- AMY plaques in familial AD (2000) (9)
- Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer’s disease (2020) (8)
- Aurones serve as probes of beta-amyloid plaques in Alzheimer's disease. (2007) (8)
- Okadaic acid enhances abnormal phosphorylation on tau proteins (1993) (8)
- Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer’s disease (2017) (7)
- High Soluble Amyloid-β42 Predicts Normal Cognition in Amyloid-Positive Individuals with Alzheimer’s Disease-Causing Mutations (2022) (7)
- Derlin‐1‐immunopositive inclusions in patients with Alzheimer's disease (2012) (7)
- Curly fibers are tau-positive strands in the pre- and post-synaptic neurites, consisting of paired helical filaments: observations by the freeze-etch and replica method (2004) (7)
- Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN) (2020) (7)
- Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. (2022) (6)
- Presenilin-1 exists in the axoplasm fraction in the brains of aged Down's syndrome subjects and non-demented individuals (1999) (6)
- Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach. (2022) (6)
- Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. (1998) (6)
- [Alzheimer's Therapeutic Research Institute]. (2017) (6)
- Corrigendum to “DCP-LA neutralizes mutant amyloid β peptide-induced impairment of long-term potentiation and spatial learning” [Behav. Brain Res. 206 (1) (2010) 151–154] (2010) (5)
- Proteomic analysis involved with synaptic plasticity improvement by GABAA receptor blockade in hippocampus of a mouse model of Alzheimer’s disease (2020) (5)
- Assignment of Alzheimer's presenilin-2 (PS-2) gene to 1q42.1 by fluorescence in situ hybridization (1996) (5)
- Clinical Features of Pittsburgh Compound-B-Negative Dementia (2012) (4)
- Correlation between right medial temporal lobe atrophy and persecutory delusions in patients with dementia of the Alzheimer's type demonstrated on VSRAD advance. (2014) (4)
- Oligomeric amyloid beta-protein as a therapeutic target in Alzheimer's disease: its significance based on its distinct localization and the occurrence of a familial variant form. (2009) (4)
- Learning Deficits in N279K Tau Transgenic Mice and an Assembly Model of Tau Protein (2004) (4)
- 605 Senile dementia with abundant neurofibrillary tangles without accompanying senile plaques. A new disease entity separable from SDAT? (1996) (3)
- Assignement of Alzheimer's presenilin-2 (PS-2) gene to 1q42.1 by fluorescence in situ hybridization (1997) (3)
- Regulation of tau exon 10 splicing by a double stem–loop structure in mouse intron 10 (2005) (3)
- A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer’s Disease (2021) (3)
- Chrysamine G and its derivative reduce amyloid beta-induced neurotoxicity in mice. (2002) (3)
- DEMENTIA WITH LEWY BODIES: INFLUENCE OF APOE GENOTYPE ON Aβ40 AND Aβ42 DEPOSITION (1998) (3)
- Neuroimaging within the Dominantly Inherited Alzheimer’s Network (DIAN): PET and MRI (2022) (3)
- Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study (2022) (2)
- Different rates of cognitive decline in autosomal dominant and late‐onset Alzheimer disease (2021) (2)
- Regulation of cholesterol efflux by amyloid β secretion (2010) (2)
- The Biological Significance of Neuropathological Lesions in Alzheimer’s Disease (1997) (2)
- An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations (2019) (2)
- Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells (2001) (2)
- 689 Amyloid β protein 42/43 (Aβ42/43) in cerebellar diffuse plaques: Enzyme-linked immunosorbent assays (ELISAs) and immunocytochemical study (1996) (2)
- Pattern of A{beta} deposition in familial Alzheimer's disease is irrespective of mutation type or cognitive status (2008) (1)
- Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner (2017) (1)
- EXTRACEREBRAL DEPOSITION OF ??-AMYLOID PROTEIN (??AP) IN ALZHEIMER??S DISEASE: 144 (1990) (1)
- Intravenous immunoglobulin improved cognitive functions in patients with Alzheimer's disease without any changes in PIB retention in the brain (2011) (1)
- CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease (2022) (1)
- Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling (2022) (1)
- Modeling Alzheimer's disease using iPS cells reveals stress phenotypes associated with intracellular beta-amyloid oligomer and differential drug responsiveness (2013) (1)
- Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease (2022) (1)
- Use of a carrier for quantitation of a new dihydropyridine calcium antagonist (OPC-13340) in human plasma by highly sensitive gas chromatography with negative-ion chemical ionization mass spectrometry. (1992) (1)
- Erratum: Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons (2016) (1)
- Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition. (2022) (1)
- UBIQUITIN IN ALZHEIMER'S PAIRED HELICAL FILAMENTS: 2 (1987) (1)
- DIFFERENT IMMUNOREACTTVITIES OF SYNTHETIC AND “NATIVE” β-AMYLOID PROTEIN (βAP) ANTISERA: 16 (1990) (1)
- The association of PS1 with the neuronal cytoskeleton and its role in Notch signaling and the regulation of neurite outgrowth (2000) (0)
- Axonal damage and astrocytosis are biological correlates of grey matter network integrity loss: a cohort study in autosomal dominant Alzheimer disease (2023) (0)
- 11C-PIB-PET imaging and cognitive statement in Alzheimer’s disease, mild cognitive impairment and healthy aging: 1-1.5 Year follow-up Study (2009) (0)
- P2-240 The neuropsychological conditions in the patients with diabetes mellitus (2006) (0)
- ＜Symposium IV＞Oligomeric Aβ is the sole culprit molecule to cause Alzheimer's disease? (2010) (0)
- The adult rodent hippocampus as a model for studying shifts in tau isoform expression (2007) (0)
- O4-06-08: Identification and characterization of a novel APP mutation (E693Δ) in familial Alzheimer's disease (2008) (0)
- PiB negative dementia: Pitfall of clinical diagnosis of Alzheimer's disease (2009) (0)
- Biology and genetics of the presenilin proteins associated with alzheimer disease (1997) (0)
- AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains. (2022) (0)
- Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons (2015) (0)
- AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains (2022) (0)
- Comparison of amyloid accumulation between Down syndrome and autosomal‐dominant Alzheimer disease (2022) (0)
- PiB negative dementia: Pitfall of clinical diagnosis of AD (2009) (0)
- [The molecular base for dementia]. (2011) (0)
- [The lessons from dementia science]. (2011) (0)
- Ubiquitin: A Newly Identified Component of Paired Helical Filaments (1988) (0)
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease (2020) (0)
- A transgenic mouse model of amyloid β oligomers: Pathological effects of the E693Δ mutation in amyloid precursor protein in vivo (2009) (0)
- Biomarker clustering in autosomal dominant Alzheimer's disease (2022) (0)
- MOTOR SYMPTOMS IN FAMILIAL ALZHEIMER’S DISEASE: FREQUENCY, SEVERITY AND PREDICTIVE VALUE (2017) (0)
- Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer’s disease: analysis of Osaka mutation-knockin mice (2017) (0)
- [A perspective on acetylcholine]. (2014) (0)
- Interaction between Presenilin holoproteins and Syntaxin isoforms (2004) (0)
- The location of PSEN1 pathogenic variants in transmembrane vs. cytoplasmic domains may alter neurodegenerative and cognitive trajectories: Findings from the DIAN study (2021) (0)
- A Study of Neuronal Expression of αB Crystallin in Autopsied Cases with Cerebral Infarction (2002) (0)
- Progressive white matter injury in autosomal dominant Alzheimer’s disease is strongly associated with cerebral microbleeds and neurodegeneration (2022) (0)
- [For the Future Study on Alzheimer's Disease in Japan]. (2017) (0)
- Rearrangement of microtubule networks by tau bearing missense mutations (2001) (0)
- Modeling Alzheimer's disease using induced pluripotent stem cells from familial and sporadic Alzheimer's disease patients (2013) (0)
- Synaptic plasticity improved by GABAA receptor blockade are based on the changed protein expression in hippocampus of a mouse model of Alzheimer‘s disease. (2022) (0)
- P4-258: Amyloid imaging of a patient with Alzheimer's disease harboring a novel APP mutation (E693Δ) (2008) (0)
- Aß Monomer, Oligomer and Fibril in Alzheimer’s Disease (2011) (0)
- Parahippocampal Atrophy is Associated with Depressive Symptoms in Alzheimer's Disease. (2016) (0)
- Author response: Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease (2021) (0)
- 419 Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein (1996) (0)
- P2-054: Pattern of Aβ deposition in familial Alzheimer's disease is not related to mutation type or cognitive status (2008) (0)
- Comparison of amyloid accumulation between Down syndrome and autosomal‐dominant Alzheimer disease (2022) (0)
- Homozygous APP mutations and Alzheimer's disease (2009) (0)
- First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer’s disease: the Dominantly Inherited Alzheimer’s Network Study (2022) (0)
- CSF Biomarkers in Down Syndrome and Autosomal Dominant Alzheimer Disease (2021) (0)
- P-058 Comparison of amyloid deposition and biochemical markers in Alzheimer’s disease, non AD type dementia and mild cognitive impairment (2007) (0)
- [Visualization of tau isoforms by splicing-site specific antibodies]. (2001) (0)
- Syntaxin specificities in the interaction with presenilin holoproteins, the accumulation of intracellular betaAPP, and the suppression of beta-amyloid production (2005) (0)
- Intraneuronal accumulation of Aβ oligomers causes abnormal tau phosphorylation, glial activation and neuronal loss in transgenic mice with APP E693Δ mutation (2010) (0)
- Distinct functions of tau isoforms in Alzheimer's disease (2003) (0)
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) (0)
- Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network (2022) (0)
- [DIAN/DIAN-J/DIAN-TU]. (2017) (0)
- Perspective on the role of the amyloid beta oligomer in Alzheimer's disease (2011) (0)
- 729 Identification and characterization of presenilin I-467, I-463 and I-374 (1996) (0)
- P3-396 Alpha-synuclein inclusion formation in pathologic aging: how important is beta-amyloid burden? (2004) (0)
- Follow-up study of PiB negative dementia (2011) (0)
- Hypercholesterolemia accelerates memory impairment in a transgenic mouse model of Abeta oligomers (2010) (0)
- Proceedings of the 11th Annual Tokyo Institute of Psychiatry International Symposium : the molecular biology of alzheimer's disease and animal models : routes to the development of new therapies (1998) (0)
- Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study. (2023) (0)
- Processing mechanism of amyloid precursor protein (APP) to produce beta/A4 protein in Alzheimer's disease brain (1992) (0)
- 152 Amyloid β protein and the cerebrovascular pathology in Alzheimer's disease (1996) (0)
- 730 Preparation of poly- and monoclonal antibodies against Alzheimer's PS-1 molecule (1996) (0)
- The clinical application of optimized AT(N) classification in Alzheimer’s clinical syndrome (ACS) and non-ACS conditions (2023) (0)
- OLIGOMERIC Aβ IS THE SOLE CULPRIT MOLECULE TO CAUSE ALZHEIMER’S DISEASE? (2010) (0)
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What Schools Are Affiliated With Hiroshi Mori?
Hiroshi Mori is affiliated with the following schools:
