Hiroshi Nakanishi

Hiroshi Nakanishi's AcademicInfluence.com Rankings

Hiroshi Nakanishi

Chemistry

#5318

World Rank

#6476

Historical Rank

Organic Chemistry

#923

World Rank

#1036

Historical Rank

chemistry Degrees

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Chemistry

Hiroshi Nakanishi's Degrees

PhD Chemistry University of Tokyo
Masters Chemistry University of Tokyo
Bachelors Chemistry University of Tokyo

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Hiroshi Nakanishi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

AMPA–Kainate Subtypes of Glutamate Receptor in Rat Cerebral Microglia (2000) (309)
Intracellular study of rat substantia nigra pars reticulata neurons in an in vitro slice preparation: electrical membrane properties and response characteristics to subthalamic stimulation (1987) (250)
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons. (2000) (207)
Cathepsin D Deficiency Induces Lysosomal Storage with Ceroid Lipofuscin in Mouse CNS Neurons (2000) (188)
Electrical membrane properties of rat subthalamic neurons in an in vitro slice preparation (1987) (173)
Age-Related Changes in Activities and Localizations of Cathepsins D, E, B, and L in the Rat Brain Tissues (1994) (161)
Reverse of Age-Dependent Memory Impairment and Mitochondrial DNA Damage in Microglia by an Overexpression of Human Mitochondrial Transcription Factor A in Mice (2008) (152)
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice (2003) (149)
Microglial functions and proteases (2003) (144)
TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia. (2015) (141)
Tryptase Inhibition Blocks Airway Inflammation in a Mouse Asthma Model1 (2002) (135)
Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice (2017) (134)
Microglia-aging: Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging (2009) (132)
The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S (2013) (119)
Neuronal and microglial cathepsins in aging and age-related diseases (2003) (115)
Involvement of Nitric Oxide Released from Microglia–Macrophages in Pathological Changes of Cathepsin D-Deficient Mice (2001) (111)
Increased Expression of Cathepsins E and D in Neurons of the Aged Rat Brain and Their Colocalization with Lipofuscin and Carboxy‐Terminal Fragments of Alzheimer Amyloid Precursor Protein (1997) (98)
Proteases involved in long-term potentiation. (2002) (94)
NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy (2017) (93)
Leptomeningeal cells activate microglia and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation (2005) (92)
Involvement of cathepsin B in the processing and secretion of interleukin‐1β in chromogranin A‐stimulated microglia (2010) (92)
Microglial Ca2+-Activated K+ Channels Are Possible Molecular Targets for the Analgesic Effects of S-Ketamine on Neuropathic Pain (2011) (91)
Potentiation of the NMDA receptor‐mediated responses through the activation of the glycine site by microglia secreting soluble factors (2006) (89)
Involvement of Cathepsin E in Exogenous Antigen Processing in Primary Cultured Murine Microglia* (2002) (87)
Two Novel Mutations in the EYS Gene Are Possible Major Causes of Autosomal Recessive Retinitis Pigmentosa in the Japanese Population (2012) (87)
Intracellular study of rat entopeduncular nucleus neurons in an in vitro slice preparation: response to subthalamic stimulation (1991) (85)
Identification of Cellular Compartments Involved in Processing of Cathepsin E in Primary Cultures of Rat Microglia (1998) (84)
Involvement of enhanced sensitivity of N-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity (2001) (83)
Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia (2013) (80)
Connection between periodontitis and Alzheimer's disease: possible roles of microglia and leptomeningeal cells. (2014) (77)
The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage (2015) (72)
Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain (2012) (72)
New Functional Aspects of Cathepsin D and Cathepsin E (2000) (70)
Transient Forebrain Ischemia Induces Increased Expression and Specific Localization of Cathepsins E and D in Rat Hippocampus and Neostriatum (1993) (67)
Involvement of caspase‐like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6‐hydroxydopamine (1998) (67)
Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation (2007) (67)
Long-Term Spatial Cognitive Impairment after Middle Cerebral Artery Occlusion in Rats: No Involvement of the Hippocampus (1995) (63)
Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice (2017) (58)
Leptomeningeal Cells Transduce Peripheral Macrophages Inflammatory Signal to Microglia in Reponse to Porphyromonas gingivalis LPS (2013) (56)
Age-dependent responses of glial cells and leptomeninges during systemic inflammation (2008) (54)
Potentiation of NMDA receptor-mediated synaptic responses by microglia. (2003) (54)
BK channels in microglia are required for morphine-induced hyperalgesia (2016) (53)
Phosphatidylserine-Containing Liposomes Inhibit the Differentiation of Osteoclasts and Trabecular Bone Loss (2010) (50)
Neostriatal evoked inhibition and effects of dopamine on globus pallidal neurons in rat slice preparations (1985) (49)
Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production by microglia (2006) (49)
Novel non-apoptotic morphological changes in neurons of the mouse hippocampus following transient hypoxic-ischemia (1999) (49)
Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy (2008) (48)
Differential involvement of perineuronal astrocytes and microglia in synaptic stripping after hypoglossal axotomy (2011) (48)
Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging (2019) (48)
Brazilian Green Propolis Suppresses the Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia (2013) (48)
Arg-Gingipain Is Responsible for the Degradation of Cell Adhesion Molecules of Human Gingival Fibroblasts and Their Death Induced by Porphyromonas gingivalis (2001) (48)
Involvement of caspase 3-like protease in methylmercury-induced apoptosis of primary cultured rat cerebral microglia (2000) (47)
Peripheral Role of Cathepsin S in Th1 Cell-Dependent Transition of Nerve Injury-Induced Acute Pain to a Chronic Pain State (2014) (47)
Phosphatidylserine-containing liposomes suppress inflammatory bone loss by ameliorating the cytokine imbalance provoked by infiltrated macrophages (2011) (46)
Inhibition of NMDA-induced outward currents by interleukin-1beta in hippocampal neurons. (2008) (45)
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats (1984) (45)
An N-methyl-d-aspartate receptor mediated excitatory postsynaptic potential evoked in subthalamic neurons in an in vitro slice preparation of the rat (1988) (45)
Increased Expression of Cathepsins E and D in Reactive Microglial Cells Associated with Spongiform Degeneration in the Brain Stem of Senescence-Accelerated Mouse (1995) (44)
Differential effects of Bcl‐2 overexpression on hippocampal CA1 neurons and dentate granule cells following hypoxic ischemia in adult mice (1999) (44)
The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells (2017) (44)
A Predominant Apoptotic Death Pathway of Neuronal PC12 Cells Induced by Activated Microglia Is Displaced by A Non-apoptotic Death Pathway Following Blockage of Caspase-3-dependent Cascade* (1999) (44)
Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice (2018) (44)
NMDA receptor-dependent formation of long-term potentiation in the rat medial amygdala neuron in an in vitro slice preparation (1993) (42)
Expression of long-term potentiation of the striatum in methamphetamine-sensitized rats (1999) (41)
Nutrients, Microglia Aging, and Brain Aging (2016) (41)
Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1β (2010) (41)
Identification of 11 novel mutations in USH2A among Japanese patients with Usher syndrome type 2 (2009) (40)
Microglial clearance of focal apoptotic synapses (2019) (39)
Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system (2016) (37)
Age-related changes in cellular localization and enzymatic activities of cathepsins B, L and D in the rat trigeminal ganglion neuron (1995) (36)
Diurnal Spatial Rearrangement of Microglial Processes through the Rhythmic Expression of P2Y12 Receptors (2013) (35)
Massively Parallel DNA Sequencing Facilitates Diagnosis of Patients with Usher Syndrome Type 1 (2014) (35)
Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice (2007) (34)
Cochlear Implant in Children with Asymptomatic Congenital Cytomegalovirus Infection (2008) (33)
Involvement of prostaglandin E2 released from leptomeningeal cells in increased expression of transforming growth factor‐β in glial cells and cortical neurons during systemic inflammation (2007) (32)
Impairment of microglial responses to facial nerve axotomy in cathepsin S–deficient mice (2007) (32)
Brazilian Green Propolis Prevents Cognitive Decline into Mild Cognitive Impairment in Elderly People Living at High Altitude. (2018) (31)
Amyloid-β fibril formation is not necessarily required for microglial activation by the peptides (2005) (30)
Expression of N-methyl-d-aspartate receptor-dependent long-term potentiation in the neostriatal neurons in an in vitro slice after ethanol withdrawal of the rat (1999) (30)
Enhancement of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials in the neostriatum after methamphetamine sensitization (2002) (30)
Excitotoxin‐Induced Neuronal Death Is Associated with Response of a Unique Intracellular Aspartic Proteinase, Cathepsin E (1998) (29)
Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse. (2010) (27)
Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D‐deficient mice (2005) (26)
Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rat (2008) (25)
The role of microglial mtDNA damage in age-dependent prolonged LPS-induced sickness behavior. (2011) (25)
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain (2019) (25)
Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer's Disease (2015) (25)
How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus? (2003) (24)
Genetic Hearing Loss Associated With Autoinflammation (2020) (24)
Enhancement of NMDA receptor-mediated synaptic potential evoked in rat medial-amygdala neuron following olfactory bulbectomy (1990) (23)
Activation of mu-calpain in developing cortical neurons following methylmercury treatment. (2003) (23)
Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation. (2007) (23)
Mutation analysis of the MYO7A and CDH23 genes in Japanese patients with Usher syndrome type 1 (2010) (23)
Cathepsin B Regulates Collagen Expression by Fibroblasts via Prolonging TLR2/NF-κB Activation (2016) (22)
The Critical Role of IL-10 in the Antineuroinflammatory and Antioxidative Effects of Rheum tanguticum on Activated Microglia (2018) (22)
Novel USH2A mutations in Japanese Usher syndrome type 2 patients: marked differences in the mutation spectrum between the Japanese and other populations (2011) (22)
Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction. (2014) (22)
Phosphatidylserine-Containing Liposomes: Potential Pharmacological Interventions Against Inflammatory and Immune Diseases Through the Production of Prostaglandin E2 After Uptake by Myeloid Derived Phagocytes (2011) (21)
Mutations of beta-amyloid precursor protein alter the consequence of Alzheimer’s disease pathogenesis (2019) (21)
The effect of ventilation tube insertion or trans-tympanic silicone plug insertion on a patulous Eustachian tube (2016) (21)
Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood–brain barrier (2015) (21)
Comprehensive analysis of syndromic hearing loss patients in Japan (2019) (20)
Cathepsin regulation on microglial function. (2020) (20)
Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat (1982) (19)
The first USH2A mutation analysis of Japanese autosomal recessive retinitis pigmentosa patients: a totally different mutation profile with the lack of frequent mutations found in Caucasian patients (2014) (19)
Cell cycle-dependent regulation of kainate-induced inward currents in microglia. (2006) (19)
Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response (2020) (18)
Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis (2017) (18)
Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia (2007) (18)
Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice. (2017) (16)
Protective effect of MK-801 on the anoxia-aglycemia induced damage in the fluorocitrate-treated hippocampal slice of the rat (1996) (15)
Arg-Gingipain Is Responsible for the Degradation of Cell Adhesion Molecules of Human Gingival Fibroblasts and Their Death Induced by Porphyromonas gingivalis (2001) (15)
Secreted gingipains from Porphyromonas gingivalis induce microglia migration through endosomal signaling by protease-activated receptor 2 (2020) (15)
Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis (2019) (14)
Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function (2018) (14)
A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain (2018) (14)
Congenital Middle Ear Cholesteatoma: Experience from 26 Surgical Cases (2013) (13)
Interferon‐α (INF‐α) and Etretinate in the Treatment of Mycosis Fungoides (1994) (13)
Hyperbaric Oxygen Therapy as Concurrent Treatment with Systemic Steroids for Idiopathic Sudden Sensorineural Hearing Loss: A Comparison of Three Different Steroid Treatments (2018) (12)
Involvement of Cathepsins in Innate and Adaptive Immune Responses in Periodontitis (2020) (12)
Pterostilbene, an active component of the dragon’s blood extract, acts as an antidepressant in adult rats (2019) (12)
Sibutramine induces potential-dependent exocytotic release but not carrier-mediated release of dopamine and 5-hydroxytryptamine. (2004) (12)
Gradual Symmetric Progression of DFNA34 Hearing Loss Caused by an NLRP3 Mutation and Cochlear Autoinflammation. (2018) (12)
Hair roots as an mRNA source for mutation analysis of Usher syndrome-causing genes (2010) (12)
An Usher syndrome type 1 patient diagnosed before the appearance of visual symptoms by MYO7A mutation analysis. (2013) (12)
Calcium-dependent hyperexcitability of hippocampal CA1 pyramidal cells in an in vitro slice after ethanol withdrawal of the rat (1994) (11)
Visual Outcomes in Japanese Patients with Retinitis Pigmentosa and Usher Syndrome Caused by USH2A Mutations (2015) (11)
Manipulation of hippocampal CA3 firing via luminopsins modulates spatial and episodic short-term memory, especially working memory, but not long-term memory (2018) (11)
Microglial Proteases: Strategic Targets for Neuroprotective Agents (2003) (10)
Relationship between tympanic membrane retraction and habitual sniffing in patients with cholesteatoma (2013) (9)
Specific Localization of Five Phosphatidylcholine Species in the Cochlea by Mass Microscopy (2010) (8)
Asymmetric distribution of acetylcholine receptors and M channels on prepyriform neurons (1983) (8)
Hyperexcitability of amygdala neurons of Senescence-Accelerated Mouse revealed by electrical and optical recordings in an in vitro slice preparation (1998) (8)
The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells (2015) (8)
[Synaptic plasticity and synaptic reorganization regulated by microglia]. (2013) (8)
Increased expression and specific localization of cathepsins E and D in vulnerable brain regions of aged and postischemic rats. (1995) (8)
Pepstatin A induces extracellular acidification distinct from aspartic protease inhibition in microglial cell lines (2003) (8)
Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE though impairment of toll-like receptor 3 cascade (2018) (7)
Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins (2022) (7)
Risk Factors and Prognostic Factors of Hearing Impairment in Neonatal Intensive Care Unit-Treated Infants (2019) (7)
Microglial cathepsin B and Porphyromonas gingivalis gingipains as potential therapeutic targets for sporadic Alzheimer's disease. (2020) (6)
Nutrients , Microglia Aging , and Brain (2016) (6)
Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling (2021) (6)
Induction of bone repair in rat calvarial defects using a combination of hydroxyapatite with phosphatidylserine liposomes. (2019) (5)
A Possible Link between Microglial Process Dysfunction and Neuropsychiatric Disorders (2014) (5)
Auditory and Vestibular Characteristics of NLRP3 Inflammasome Related Autoinflammatory Disorders: Monogenic Hearing Loss Can Be Improved by Anti-interleukin-1 Therapy (2022) (5)
Characterization of cathepsins E and D accumulated at early stages of neuronal damage in hippocampal neurons of rats. (1995) (5)
Cathepsin E in the central nervous system. (1998) (5)
Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia (2013) (4)
Stem cells from human exfoliated deciduous teeth attenuate mechanical allodynia in mice through distinct from the siglec-9/MCP-1-mediated tissue-repairing mechanism (2021) (4)
Diaphragmatic rupture due to violent cough during tracheostomy. (2010) (4)
Proteases and Synaptic Activity (2005) (4)
Hereditary isolated ossicular anomalies in two generations of patients. (2011) (4)
Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease (2022) (4)
Author Correction: Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice (2018) (4)
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications (2022) (4)
BRAZILIAN PROPOLIS IMPROVES COGNITIVE FUNCTIONS AND REGULATES SERUM CYTOKINE BALANCES IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AT HIGH ALTITUDE (2014) (3)
Interferon-alpha (INF-alpha) and etretinate in the treatment of mycosis fungoides. (1994) (3)
A case of improved hearing with cochlear implantation in Gaucher disease type 1. (2017) (3)
Experimental studies on immunogenesis of otitis media with effusion. (1985) (3)
Neural stem cell–specific ITPA deficiency causes neural depolarization and epilepsy (2020) (3)
An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons (2016) (3)
Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats (2017) (3)
Old and new inflammation and infection hypotheses of Alzheimer's disease: focus on Microglia-aging for chronic neuroinflammation. (2017) (3)
Lateral hypothalamus and local stimulation induced postsynaptic responses in zona incerta neurons in an in vitro slice preparation of the rat (1992) (3)
Ultrastructural Localization of Cochlin in the Rat Cochlear Duct (2009) (2)
Update on Findings about Sudden Sensorineural Hearing Loss and Insight into Its Pathogenesis (2022) (2)
Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury (2021) (2)
BK channel in microglia as a potent therapeutic molecular target for neuropathic pain (2015) (2)
The Dual Nature of Microglia in Alzheimer's Disease: A Microglia-Neuron Crosstalk Perspective. (2022) (2)
Therapeutic Devices for Motor Symptoms in Parkinson’s Disease: Current Progress and a Systematic Review of Recent Randomized Controlled Trials (2022) (2)
Otitis media with effusion and endotoxin. (1985) (2)
Novel roles of microglia (2014) (2)
[Involvement of proteinases produced by both neurons and microglia in neuronal lesion and death pathways]. (1998) (2)
The downward spiral of periodontitis and diabetes in Alzheimer׳s disease: Extending healthy life expectancy through oral health (2015) (2)
Involvement of Microglial Cathepsin B in Pro-Interleukin-1 Processing and Persistent Pain (2012) (1)
Regulation of myeloid derived phagocytes by phosphatidylserine-containing liposomes: Possible involvement of prostaglandin E2 and the potential therapeutic application (2011) (1)
An Ameloblastoma in the Middle Ear. (2019) (1)
[Tree pollens and nasal allergy--etiological survey of specific IgE to Japanese cedar by RAST in 50 cities, towns and villages in the Wakayama Prefecture]. (1986) (1)
A Case of Carcinoid Tumor of the Ear (2013) (1)
[A case of hypopharyngeal cancer responding to recombinant interferon-gamma (KW-2202)]. (1987) (1)
Preferential inhibitory effects of S-ketamine on both NMDA receptor currents and neuropathic pain (2010) (1)
NMDA receptor-dependent formation of long-term potentiation (LTP) in the rat amygdala (AMG) (1992) (1)
Overexpression of Cathepsin E Interferes with Neuronal Differentiation of P19 Embryonal Teratocarcinoma Cells by Degradation of N-cadherin (2017) (1)
Rat Microglia Cells: Their Culture, Isolation and Phagocytic Activity (2008) (1)
Differential pathways for the interleukin-1β production activated by chromogranin A and Aβ in microglia (2013) (1)
Tree pollen and nasal allergy. VI. Relationship between age and positive RAST reactions to Japanese cedar pollen. (1986) (1)
ETIOLOGICAL SURVEY OF SPECIFIC IgE TO JAPANESE CEDAR BY RAST IN 50 CITIES, TOWNS AND VILLAGES IN WAKAYAMA PREFECTURE (1986) (1)
[Microglia and synaptic reorganization: focus on the movement and functions of microglial processes]. (2013) (1)
A Case of Lemierre Syndrome (2008) (1)
Treatment of Patulous Eustachian Tube (2010) (1)
[Neuronal cell death and intracellular proteinase functions]. (1995) (1)
Human β-Defensin 3 Inhibits Porphyromonas Gingivalis Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L (2022) (0)
Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE though impairment of toll-like receptor 3 cascade (2018) (0)
Evaluation of Auditory Findings in Subjects with Autosomal Dominant Non-Syndromic Hearing Loss Caused by a TECTA Mutation (2021) (0)
Trabecular Bone Loss Inhibit the Differentiation of Osteoclasts and Phosphatidylserine-Containing Liposomes (2010) (0)
Editorial Note for Journal of Neurological Disorders (2020) (0)
Effect of caudal epidural blockade in patients with lumbarspinal stenosis (1990) (0)
Me 1207 in the treatment of superficial purulent diseases (1992) (0)
Multiple functions of osteoclasts and potential usefulness of phosphatidylserine-containing liposomes on bone diseases (2012) (0)
A case of branchiogenic carcinoma. (1988) (0)
A Case of Congenital Cholesteatoma within the Tympanic Membrane that Recovered through Epithelization of the Remaining Matrix (2017) (0)
Experimental Studies on Immunogenesis of Otitis Media with Effusion (1985) (0)
Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice (2017) (0)
Tree pollen and nasal allergy. (XIII). Distribution of Japanese cedar pollen in Wakayama and southern Osaka in 1988. (1989) (0)
Pleomorphic adenoma of nasal septum; A report of two cases. (1989) (0)
Clinical Analysis of Secondary Acquired Cholesteatoma (2017) (0)
Synaptic stripping and beyond: Microglia or astrocytes? (2012) (0)
Education of New Otolaryngologists Regarding Otitis Media with Effusion to Enhance Their Understanding of Eustachian Tube Dysfunction (2021) (0)
Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat. (1980) (0)
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain (2019) (0)
A Case of Temporal Bone Phosphaturic Mesenchymal Tumor That Was Treated by Surgery (2021) (0)
Author Correction: Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice (2018) (0)
Postoperative Course of Pars Flaccida Cholesteatoma Patients With Habitual Sniffing (2020) (0)
Neurons in the hippocampus of adult mice undergo novel morphological changes after transient ischemia (1998) (0)
Two Cases of Large Vestibular Aqueduct Syndrome with SLC26A4 Mutations (2009) (0)
Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury (2021) (0)
ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway (2022) (0)
Three Cases of Temporal Bone Osteoradionecrosis after Nasopharyngeal Carcinoma Treatment (2012) (0)
Neurodegeneration and intracellular proteinases (1996) (0)
Tree pollens and nasal allergy. IV. Airborne tree pollens on the roof of Wakayama Red Cross Hospital. (1986) (0)
Two Cases of Sniff-Type Patulous Eustachian Tube (2021) (0)
A Study on Cochlear Implantation (2013) (0)
[Problem and assignment for distinguishing the Usher syndrome type]. (2012) (0)
LABORATORY AND CLINICAL STUDIES OF BAY o 9867 (CIPROFLOXACIN) IN DERMATOLOGICAL FIELDS (1985) (0)
THE STUDY OF SUPPRESSION OF HYPOXIA-INDUCED INFLAMMATION BY TIBETAN MEDICINE RATANASAMPIL IN MICROGLIA CELLS (2017) (0)
Two Cases of Malignant External Otitis Treated with Surgery (2011) (0)
Assay of DP-specific IgG antibody using ELISA. (1985) (0)
18 Microglial Proteases (2007) (0)
TNF-α signaling and cathepsin B (2013) (0)
Auditory Evaluation in a Patient with HDR Syndrome (2019) (0)
Short communication A of m-calpain in developing cortical neurons following methylmercury treatment (2003) (0)
The role of BK channels in spinal microglia for the induction of neuropathic pain in mice (2019) (0)
Neural stem cell specific ITPA deficiency causes depolarization of neurons, resulting in epileptic seizure and early death in mice (2019) (0)
A Case of Multilocular Temporomandibular Joint Ganglion Manifesting as an External Auditory Canal Mass (2017) (0)
Glottic adhesion and stenosis in a patient with systemic lupus erythematosus (2019) (0)
Ratanasampil Suppresses the Hypoxia-Related Inflammatory Responses by Inhibiting Oxidative Stress and NF-kB Activation in Microglia (2018) (0)
A Case of Actinomycosis of the Middle Ear (2018) (0)
Differential pathways for the interleukin-1β production activated by chromogranin A and Aβ in microglia (2013) (0)
Concentration of cefuzonam in otorrhea discharge. (1990) (0)
Protective effects of microglia-conditioned medium (MCM) against NMDA-induced dendritc injury through an inhibition of non-selective cation conductance (2010) (0)
Inflammation in a Mouse Asthma Model Tryptase Inhibition Blocks Airway (2002) (0)
Schwannoma of cervical vagus nerve; A case report. (1990) (0)
Generation of CSF1-Independent Ramified Microglia-Like Cells from Leptomeninges In Vitro (2020) (0)
Targeting cellular gaps using Janus nanoparticles containing cationic polymers and surfactant lipids. (2023) (0)
Evaluation of the clinical findings in patients with Usher syndrome type 1 (2017) (0)
Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling (2021) (0)
Editorial: Autoinflammation of the inner ear (2022) (0)
A Case of Waardenburg Syndrome Type 1 Caused by a Novel Mutation in PAX3 (2013) (0)
A Case of Encephalocele in the Temporal Bone Repeating Intracranial Infection (2021) (0)
Cathepsin E-dependent production of elastase in neutrophils induces mechanical allodynia in experimental autoimmune encephalomyelitis (2019) (0)
Pterostilbene, an active component of the dragon’s blood extract, acts as an antidepressant in adult rats (2019) (0)
A case of tonsillar tuberculosis. (1987) (0)
ホスファチジルセリン(PS)-リポソームの抗炎症作用を用いたAlzheimer病の治療へのアプローチ(THE APPROACH TO THE TREATMENT OF ALZHEIMER'S DISEASE USING ANTI-INFLAMMATORY EFFECTS OF PHOSPIHATIDYLSERINE(PS)-LIPOSOMES) (2003) (0)
Cathepsin-dependent neuronal death pathways induced by methylmercury (2011) (0)
Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functions (2008) (0)
Mechanisms Underlying Neuronal Death Induced by Activated Microglia (2002) (0)
Skin penetration of grepafloxacin and its clinical use in the treatment of skin and skin structure infection (1995) (0)
The suppression effects of Ratanasampil on oxidative stress-induced neuronal damage and microglia-mediated neuroinflammation (2019) (0)
Bacteriological, Pharmacokinetic and Clinical Studies on Banan tab in Otorhinolaryngological Infections. (1993) (0)
Clinical effect of AA-673 nasal spray in allergic rhinitis. (1987) (0)
Possible involvement of N-methyl-D-aspartate (NMDA) receptors in activation of excitatory postsynaptic potentials evoked in rat subthalamic (STH) neurons in vitro (1987) (0)
Enhancement of NMDA receptor-mediated synaptic response following olfactory bulbectomy in rat medial-amygdala (AMG) neuron in vitro slice preparation (1990) (0)
Unusual Molecular Form of Cathepsin E Expressed at Early Stage of Excitotoxic Damage in Hippocampal Neurons of Rats (1994) (0)
Overexpression of Cathepsin E Interferes with Neuronal Differentiation of P19 Embryonal Teratocarcinoma Cells by Degradation of N-cadherin (2016) (0)
Japanese Cedar Pollinosis and its Countermeasures in Wakayama Prefecture (1989) (0)
RATANASAMPIL SUPPRESSES THE HYPOXIA-REOXYGENATION–INDUCED INFLAMMATORY RESPONSE THROUGH INHIBITING NF-KAPPA B ACTIVATION IN MICROGLIA (2018) (0)
Lessons from cathepsin deficient mice on human brain diseases (2015) (0)
An Atypical Usher Syndrome Type 2 Patient with USH2A Mutations (2010) (0)
Pathology and Treatment of Patulous Eustachian Tube in Patients with and without Habitual Sniffing (2018) (0)
A familial case of inherited autosomal-dominant non-syndromic hearing loss caused by a TECTA mutation in the zona pellucida domain of alpha-tectorin: indication of elevation of hearing thresholds in high frequencies with age (2022) (0)
Evaluation of the auditory and vestibular functions in patients with vestibular schwannoma (2021) (0)
Changes in clinical symptoms and Dermatophagoides pteronyssinus specific IgG antibodies during house dust hyposensitization therapy. (1986) (0)
[Tree pollens and nasal allergy (XI). Relationship of age to the total IgE level, Japanese cedar RAST score, Japanese cedar-specific IgG antibodies and IgG subclass]. (1989) (0)
Murine Microglia Antigen Processing in Primary Cultured Involvement of Cathepsin E in Exogenous REGULATION : ENZYME CATALYSIS (2002) (0)
Relationship between aggregational state of Aβ peptides and microglial activation (2006) (0)
A Case of Branchio-oto Syndrome Caused by EYA1 Mutation (2017) (0)
Experience of Cartilage Conduction Hearing Aids (2021) (0)
BK+ channels contribute to the cellular activation of microglia: A big channel in small glia (2013) (0)
P014: Touch Smear Cytology in Salivary Gland Tumor (2007) (0)
Mutation Analysis of the USH2A Gene in Japanese Patients with Autosomal Recessive Retinitis Pigmentosa (2014) (0)
Drip infusion therapy of antiviral agent for sudden deafness. (1988) (0)
Clinical effect of AA-673 tablets in allergic rhinitis. (1988) (0)
Preventing and Reversing ?Microglia-Aging? by Nature Materials for Slow Brain-Aging (2013) (0)
Clinical evaluation of IAP (Immunosuppressive acidic protein) in the serum of patients with malignant tumors of head and neck--with special reference to prognosis and immunological parameters. (1984) (0)
A Case of Congenital Open-Type Cholesteatoma Diagnosed by Diffusion-Weighted MRI Using the PROPELLER Technique (2021) (0)
Evaluation of FK037 in dermatolog (1994) (0)
Journal of Neurological Disorders (2020) (0)

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What Schools Are Affiliated With Hiroshi Nakanishi?

Hiroshi Nakanishi is affiliated with the following schools:

Hamamatsu University
Kyushu University
Yasuda Women's University
University of Tokyo
Institute of Science Tokyo
University of Washington
Kyoto University