Hiroshi Okamoto

Q: What Schools Are Affiliated With Hiroshi Okamoto

Hiroshi Okamoto is affiliated with the following schools: Kyoto University, Hokkaido University, Tohoku University, Kobe Gakuin University, University of Oxford, Kanazawa University, Shonan Institute of Technology, University of Tokyo, Institute of Science Tokyo, University of Florence, Osaka University

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Hiroshi Okamoto

Philosophy

#5709

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#8592

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Logic

#2940

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#4019

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Hiroshi Okamoto

Biology

#7680

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#10637

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Cell Biology

#286

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#294

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Molecular Biology

#906

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#929

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Biochemistry

#1065

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#1180

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biology Degrees

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Philosophy
Biology

Hiroshi Okamoto's Degrees

PhD Molecular Biology University of Tokyo
Doctorate Medicine University of Tokyo

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Hiroshi Okamoto's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. (2003) (666)
Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27 (1983) (641)
CD38 is critical for social behaviour by regulating oxytocin secretion (2007) (609)
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets (1981) (578)
A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits (2000) (534)
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. (2001) (479)
A novel gene activated in regenerating islets. (1988) (450)
Cyclic ADP-ribose in insulin secretion from pancreatic beta cells. (1993) (429)
Translational control of proinsulin synthesis by glucose (1980) (294)
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP. (1993) (267)
Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis. (1982) (266)
Effect of Antisense Oligonucleotides against Cholesteryl Ester Transfer Protein on the Development of Atherosclerosis in Cholesterol-fed Rabbits* (1998) (243)
Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene. (1990) (236)
RAGE Control of Diabetic Nephropathy in a Mouse Model (2006) (235)
CD38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose, [Ca2+] i , and Insulin Secretion* (1999) (222)
Nucleotide sequence divergence and functional constraint in VIP precursor mRNA evolution between human and rat (1985) (220)
Altered Stoichiometry of FKBP12.6 Versus Ryanodine Receptor as a Cause of Abnormal Ca2 Leak Through Ryanodine Receptor in Heart Failure (2000) (218)
Cyclic ADP-ribose Binds to FK506-binding Protein 12.6 to Release Ca2+ from Islet Microsomes* (1997) (207)
The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. (1997) (205)
The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells. (1999) (204)
Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function (2012) (181)
Septic Shock Is Associated with Receptor for Advanced Glycation End Products Ligation of LPS (2011) (180)
Amelioration of Diabetes Mellitus in Partially Depancreatized Rats by Poly(ADP-ribose) Synthetase Inhibitors: Evidence of Islet B-Cell Regeneration (1984) (174)
ADP ribosyl cyclase activity of a novel bone marrow stromal cell surface molecule, BST‐1 (1994) (173)
Identification of a Receptor for Reg (Regenerating Gene) Protein, a Pancreatic β-Cell Regeneration Factor* (2000) (171)
Increased Expression of HIP/PAP and Regenerating Gene III in Human Inflammatory Bowel Disease and a Murine Bacterial Reconstitution Model (2003) (162)
Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport[S] (2010) (161)
Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation. (2001) (158)
Isolation and structure of T-kinin. (1983) (157)
Transgenic Mice Overexpressing Type 2 Nitric-oxide Synthase in Pancreatic β Cells Develop Insulin-dependent Diabetes without Insulitis* (1998) (156)
Cyclic ADP-ribose modulates Ca2+ release channels for activation by physiological Ca2+ entry in bullfrog sympathetic neurons (1994) (152)
Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells. (2002) (149)
Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy. (2007) (149)
Structure, chromosomal localization, and expression of mouse reg genes, reg I and reg II. A novel type of reg gene, reg II, exists in the mouse genome. (1993) (141)
Amelioration of vasospasm after subarachnoid hemorrhage in transgenic mice overexpressing CuZn-superoxide dismutase. (1999) (139)
Molecular basis of experimental diabetes: Degeneration, oncogenesis and regeneration of pancreatic B‐cells of islets of Langerhans (1985) (133)
Cyclic ADP-ribose and Inositol 1,4,5-Trisphosphate as Alternate Second Messengers for Intracellular Ca2+ Mobilization in Normal and Diabetic β-Cells* (1998) (130)
Human lens epithelial cell line. (1998) (128)
Generation of Nicotinic Acid Adenine Dinucleotide Phosphate and Cyclic ADP-Ribose by Glucagon-Like Peptide-1 Evokes Ca2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets (2008) (126)
Advanced glycation endproduct-induced calcium handling impairment in mouse cardiac myocytes. (2002) (123)
Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice. (2002) (123)
Reg gene expression is increased in rat gastric enterochromaffin-like cells following water immersion stress. (1996) (119)
Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice (2007) (116)
Cloning and characterization of cDNA encoding rat ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (homologue to human CD38) from islets of Langerhans. (1994) (110)
Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38. (1994) (107)
Muscarinic Receptor-mediated Dual Regulation of ADP-ribosyl Cyclase in NG108-15 Neuronal Cell Membranes* (1997) (107)
Requirement of Calmodulindependent Protein Kinase II in Cyclic ADP-ribose-mediated Intracellular Ca2+ Mobilization (*) (1995) (106)
Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIIIα, RegIIIβ, RegIIIγ (1997) (102)
Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). (2006) (98)
Autoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin- dependent diabetes patients. (1998) (97)
T-kininogen--the major plasma kininogen in rat adjuvant arthritis. (1985) (96)
Identification of Cyclic ADP-ribose-dependent Mechanisms in Pancreatic Muscarinic Ca2+ Signaling Using CD38 Knockout Mice* (2001) (95)
DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin. (1981) (95)
Autoantibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: effects on insulin release from human islets. (1999) (93)
On the submitochondrial localization of l-kynurenine-3-hydroxylase. (1967) (93)
Effect of Poly(ADP-ribose) Synthetase Inhibitor Administration to Rats Before and After Injection of Alloxan and Streptozotocin on Islet Proinsulin Synthesis (1983) (93)
Nicotinamide prolongs survival of primary cultured hepatocytes without involving loss of hepatocyte-specific functions. (1989) (92)
CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues. (2002) (92)
Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. (1996) (91)
Important role of heparan sulfate in postnatal islet growth and insulin secretion. (2009) (89)
Angiotensin II Stimulates Endothelial NO Synthase Phosphorylation in Thoracic Aorta of Mice With Abdominal Aortic Banding Via Type 2 Receptor (2006) (88)
REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer. (2005) (87)
Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly(adenosine diphosphate ribose) synthetase inhibitors. (1985) (86)
Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing. (1997) (86)
Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets. (1980) (85)
Kininogen substrates for trypsin and cathepsin D in human, rabbit and rat plasmas. (1983) (85)
Anti-Inflammatory Activity of PYNOD and Its Mechanism in Humans and Mice (2010) (84)
Angiotensin II-induced vasodilation via type 2 receptor: role of bradykinin and nitric oxide. (2008) (81)
A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro (1998) (79)
Expression of reg protein in rat regenerating islets and its co-localization with insulin in the Beta cell secretory granules (1990) (79)
Angiotensin Type 2 Receptor–Mediated Phosphorylation of eNOS in the Aortas of Mice With 2-Kidney, 1-Clip Hypertension (2005) (75)
Anti‐CD38 autoimmunity in patients with chronic autoimmune thyroiditis or Graves' disease (2001) (74)
Cyclin D1 activation through ATF‐2 in Reg‐induced pancreatic β‐cell regeneration (2006) (74)
Roles of the AGE‐RAGE System in Vascular Injury in Diabetes a (2000) (73)
Autoimmunity to CD38 and GAD in Type I and Type II diabetes: CD38 and HLA genotypes and clinical phenotypes (2002) (73)
Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region. (2000) (72)
Purification and characterization of proinsulin mRNA from rat B-cell tumor. (1979) (71)
Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III. (2004) (71)
Displays of paternal mouse pup retrieval following communicative interaction with maternal mates (2013) (69)
Up-Regulation of Angiotensin II Type 2 Receptor in Rat Thoracic Aorta by Pressure-Overload (2004) (68)
Human REG I gene is up‐regulated in intrahepatic cholangiocarcinoma and its precursor lesions (2001) (67)
Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages (2004) (66)
Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice (2008) (64)
bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer protein. (2000) (62)
Two enzymes concerned in peptide hormone α-amidation are synthesized from a single mRNA (1990) (61)
Lysine 129 of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) Participates in the Binding of ATP to Inhibit the Cyclic ADP-ribose Hydrolase* (1997) (60)
Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1. (2001) (59)
The CD38-cyclic ADP-ribose signalling system in insulin secretion: molecular basis and clinical implications (1997) (58)
Nucleotide sequence determination of chicken glucagon precursor cDNA (1990) (58)
Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas. (2006) (57)
Stimulation of Cyclic GMP Production via AT2 and B2 Receptors in the Pressure-Overloaded Aorta After Banding (2004) (56)
Pancreatic Regenerating Gene Overexpression in the Nonobese Diabetic Mouse During Active Diabetogenesis (1996) (56)
Liposomal membranes. 2. Synthesis of a novel pyrene-labeled lecithin and structural studies on liposomal bilayers (1980) (56)
Reg protein is overexpressed in gastric cancer cells, where it activates a signal transduction pathway that converges on ERK1/2 to stimulate growth (2002) (56)
Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes (1981) (55)
RelA-Associated Inhibitor Blocks Transcription of Human Immunodeficiency Virus Type 1 by Inhibiting NF-κB and Sp1 Actions (2002) (55)
Immunohistochemical Expression of Chromogranins A and B, Prohormone Convertases 2 and 3, and Amidating Enzyme in Carcinoid Tumors and Pancreatic Endocrine Tumors (2000) (54)
Transgenic CuZn-Superoxide Dismutase Inhibits NO Synthase Induction in Experimental Subarachnoid Hemorrhage (2001) (54)
Expression of regenerating gene I in gastric adenocarcinomas (2004) (53)
Isolation, structural determination and expression of a novel reg gene, human regI beta. (1994) (53)
Reg I-knockout mice reveal its role in regulation of cell growth that is required in generation and maintenance of the villous structure of small intestine (2007) (53)
Glucose stimulation of the proinsulin synthesis in isolated pancreatic islets without increasing amount of proinsulin mRNA (1978) (52)
Cyclic AMP regulation of pro-vasoactive intestinal polypeptide/PHM-27 synthesis in human neuroblastoma cells. (1984) (52)
Human REG family genes are tandemly ordered in a 95‐kilobase region of chromosome 2p12 (1995) (52)
rig encodes ribosomal protein S15 The primary structure of mammalian ribosomal protein S15 (1991) (51)
Identification of mouse orthologue of endogenous secretory receptor for advanced glycation end-products: structure, function and expression. (2006) (51)
REG gene expression is associated with the infiltrating growth of gastric carcinoma (2003) (51)
Expression of Reg/PAP family members during motor nerve regeneration in rat. (2005) (50)
AP-1B-mediated protein sorting regulates polarity and proliferation of intestinal epithelial cells in mice. (2013) (50)
Advanced Glycation End Products Increase Collagen-specific Chaperone Protein in Mouse Diabetic Nephropathy* (2004) (50)
Effect of HDL, from Japanese white rabbit administered a new cholesteryl ester transfer protein inhibitor JTT-705, on cholesteryl ester accumulation induced by acetylated low density lipoprotein in J774 macrophage. (2002) (49)
Neutrophil chemoattractant 2 beta regulates expression of the Reg gene in injured gastric mucosa in rats. (2000) (49)
Tissue kallikrein is synthesized and secreted by human vascular endothelial cells. (2003) (47)
NAD(+)-glycohydrolase from Streptococcus pyogenes shows cyclic ADP-ribose forming activity. (1995) (46)
Pharmacological properties of T-kinin (isoleucyl-seryl-bradykinin) from rat plasma. (1983) (46)
Expression of REG Protein During Cell Growth and Differentiation of Two Human Colon Carcinoma Cell Lines (1999) (46)
In vivo glycyrrhizin accelerates liver regeneration and rapidly lowers serum transaminase activities in 70% partially hepatectomized rats. (2008) (45)
Alterations of the plasma selenium concentrations and the activities of tissue peroxide metabolism enzymes in streptozotocin-induced diabetic rats. (1988) (45)
Adenylate cyclase from Brevibacterium liquefaciens. I. Purification, crystallization, and some properties. (1974) (45)
Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetes. (1999) (44)
Detection of carcinogen-induced DNA breaks by nick translation in permeable cells. (1983) (44)
Autoantibodies to REG, a beta‐cell regeneration factor, in diabetic patients (2004) (44)
Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma. (1997) (44)
Pancreatic β-Cell Death, Regeneration and Insulin Secretion: Roles of Poly(ADP-Ribose) Polymerase and Cyclic ADP-Ribose (2002) (44)
Mosaic evolution of prepropancreatic polypeptide. (1986) (44)
Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNβ (2006) (43)
Inducible nitric oxide synthase following hypoxia in rat cultured glial cells (1996) (43)
Nicotinamide‐adenine dinucleotide regulates muscarinic receptor‐coupled K+ (M) channels in rodent NG108‐15 cells. (1995) (43)
A novel ryanodine receptor expressed in pancreatic islets by alternative splicing from type 2 ryanodine receptor gene. (2010) (43)
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production. (2011) (43)
CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice (2013) (42)
Receptor for Advanced Glycation End Products Is a Promising Target of Diabetic Nephropathy (2005) (42)
NF-κB is required for CD38-mediated induction of Cγ1 germline transcripts in murine B lymphocytes (2002) (42)
Complete Nucleotide Sequence of Human Vasoactive Intestinal Peptide/PHM‐27 Gene and Its Inducible Promoter a (1988) (42)
CD 38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose (1999) (42)
Deficit of CD38/cyclic ADP-ribose is differentially compensated in hearts by gender. (2003) (41)
Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic beta cells. Evidence for improved glucose tolerance and enhanced insulin secretion by VIP and PHM-27 in vivo. (1994) (41)
Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37. (2000) (40)
Structural determination and characterization of a 40 kDa protein isolated from rat 40 S ribosomal subunit (1994) (40)
Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells. (1999) (39)
Molecular Biology of the Islets of Langerhans: Index (1990) (38)
Upregulation of REG Iα accelerates tumor progression in pancreatic cancer with diabetes (2010) (38)
Reproductive Experience Affects Parental Retrieval Behaviour Associated with Increased Plasma Oxytocin Levels in Wild‐Type and Cd38‐Knockout Mice (2011) (37)
Synergistic stimulation of VIPPHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells (1985) (37)
Expression Profile of the REG Gene Family in Colorectal Carcinoma (2011) (36)
Interleukin-8 Regulates Expression of Reg Protein in Helicobacter pylori-Infected Gastric Mucosa (2005) (36)
Flavin adenine dinucleotide requirement for kynurenine hydroxylase of rat liver mitochondria. (1967) (36)
Molecular cloning of cDNAs for mouse low-molecular-weight and high-molecular-weight prekininogens. (1997) (36)
CD38 positively regulates postnatal development of astrocytes cell‐autonomously and oligodendrocytes non‐cell‐autonomously (2017) (35)
Islet β-Cell Regeneration and Reg Genes (1992) (35)
Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice (2016) (35)
FKBP12.6 disruption impairs glucose-induced insulin secretion. (2008) (35)
The role of poly(ADP-ribose) synthetase in the development of insulin-dependent diabetes and islet B-cell regeneration. (1985) (35)
Inhibition of lipoxygenase by phenolic compounds. (1991) (34)
CD38 gene disruption inhibits the contraction induced by alpha-adrenoceptor stimulation in mouse aorta. (2003) (34)
Molecular Biology of the Islets of Langerhans: The molecular basis of experimental diabetes (1990) (34)
Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes. (1990) (34)
Nicotinamide Inhibits IRF-1 mRNA Induction and Prevents IL-1β-Induced Nitric Oxide Synthase Expression in Pancreatic β Cells (1995) (34)
Mosaic evolution of prepropancreatic polypeptide. II. Structural conservation and divergence in pancreatic polypeptide gene. (1988) (33)
The immunohistochemical evaluation of PSP/reg-protein in normal and diseased human pancreatic tissues (1993) (33)
Effect of JTT-705 on cholesteryl ester transfer protein and plasma lipid levels in normolipidemic animals. (2003) (32)
Temporal changes of neurogenesis in the mouse hippocampus after experimental subarachnoid hemorrhage (2003) (32)
Evolutionary conservation of the insulinoma gene rig and its possible function. (1987) (32)
Cyclin D1 activation through ATF-2 in Reg-induced pancreatic beta-cell regeneration. (2006) (32)
Role of Cyclic ADP-Ribose in ATP-activated Potassium Currents in Alveolar Macrophages* (1997) (31)
Prevention of Reg I-induced β-cell apoptosis by IL-6/dexamethasone through activation of HGF gene regulation. (2013) (31)
Fiber-modified adenovirus vectors containing the TAT peptide derived from HIV-1 in the fiber knob have efficient gene transfer activity (2007) (31)
Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination (2019) (30)
Stimulation of angiotensinogen production in primary cultures of rat hepatocytes by glucocorticoid, cyclic adenosine 3',5'-monophosphate, and interleukin-6. (1992) (30)
Activation of regenerating gene Reg in rat and human hearts in response to acute stress. (2005) (30)
Regional Distribution of Kininase in Rat Brain (1981) (30)
The CD38-cyclic ADP-ribose signaling system in insulin secretion. (1999) (30)
Regulation of interleukin-1 synthesis by histamine produced by mouse peritoneal macrophages per se. (1990) (29)
Intraductal papillary mucinous neoplasm originating from a jejunal heterotopic pancreas: report of a case (2014) (28)
Expression of kininogen, kallikrein and kinin receptor genes by rat cardiomyocytes. (2000) (28)
Angiotensinogen production by rat hepatoma cells is stimulated by B cell stimulatory factor 2/interleukin‐6 (1989) (28)
A diurnal variation of vasoactive intestinal peptide (VIP) mRNA under a daily light-dark cycle in the rat suprachiasmatic nucleus (2004) (28)
Angiotensin-converting enzyme inhibitor enhances liver regeneration following partial hepatectomy: involvement of bradykinin B2 and angiotensin AT1 receptors. (2007) (28)
New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose. (1995) (28)
Solubilization and partial purification of kynurenine hydroxylase from mitochondrial outer membrane and its electron donors. (1969) (27)
Poly(ADP‐ribose) synthetase inhibitors enhance streptozotocin‐induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks (1982) (27)
Pancreatic regenerating protein (reg I) and reg I receptor mRNA are upregulated in rat pancreas after induction of acute pancreatitis. (2006) (27)
Novel Gene Activated in Rat Insulinomas (1986) (27)
DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors. (1983) (26)
Attenuation of nitric oxide synthase induction in IRF-1-deficient glial cells (1997) (26)
Perfluorinated Aryls in the Design of Chiral Brønsted Acid Catalysts: Catalysis of Enantioselective [4 + 2] Cycloadditions and Ene Reactions of Imines with Alkenes by Chiral Mono-Phosphoric Acids with Perfluoroaryls (2016) (26)
Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system. (2000) (25)
Dynamic changes in AP-1 transcription factor DNA binding activity in rat brain following administration of antidepressant amitriptyline and brain-derived neurotrophic factor (2003) (25)
Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans. (1995) (25)
Amino acids and peptides. XXXV. Facile preparation of p-nitroanilide analogs by the solid-phase method. (2000) (25)
All‐trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL‐60 cells: possible involvement of protein kinase C‐δ (2011) (25)
Influence of L-thyroxine on kynurenine 3-hydroxylase, monoamine oxidase, and rotenone-insensitive NADH-cytochrome c reductase in mitochondrial outer membrane. (1971) (25)
Formation of Silver Nanoparticles in Poly(methyl methacrylate) by UV Irradiation (2001) (24)
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: inhibition of hydrolysis by ATP and physiological significance. (1997) (24)
Thiazolidinediones inhibit REG Ialpha gene transcription in gastrointestinal cancer cells. (2009) (24)
Kininogen expression by rat vascular smooth muscle cells: stimulation by lipopolysaccharide and angiotensin II. (1998) (24)
Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors. (1992) (23)
Effects of low-dose γ-irradiation on the cell cycle duration of barley roots (1995) (23)
Interleukin-6 as a mediator responsible for inflammation-induced increase in plasma angiotensinogen. (1993) (23)
Changes in activity of the renin-angiotensin system of the rat by induction of acute inflammation. (1989) (23)
Kynurenine metabolism in hyperthyroidism. A biochemical basis for the low NAD(P) level in hyperthyroid rat liver. (1971) (22)
REG I Expression Predicts Long-term Survival among Locally Advanced Thoracic Squamous Cell Esophageal Cancer Patients Treated with Neoadjuvant Chemoradiotherapy Followed by Esophagectomy (2006) (22)
Acute phase responses of plasma angiotensinogen and T-kininogen in rats. (1987) (22)
Islet beta-cell regeneration and reg genes. (1992) (22)
REG I as a marker for human pancreatic acinoductular cells. (2004) (22)
Intramitochondrial localization of kynurenine aminotransferase. (1970) (22)
Cholesteryl ester transfer protein promotes the formation of cholesterol-rich remnant like lipoprotein particles in human plasma. (2007) (22)
Cloning and structural determination of human peptide YY cDNA and gene. (1993) (22)
Deletion of platelet-derived growth factor receptor-β improves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice (2011) (21)
Complete Nucleotide Sequence of Human reg Gene and Its Expression in Normal and Tumoral Tissues (2001) (21)
Measurement of serum PSP/reg-protein concentration in various diseases with a newly developed enzyme-linked immunosorbent assay (1995) (21)
Inhibition by kynurenine metabolites of proinsulin synthesis in isolated pancreatic islets (1978) (21)
[24] T-kinin and T-kininogen (1988) (21)
Lipid Alterations in Renal Membrane of Stroke‐Prone Spontaneously Hypertensive Rats (1989) (20)
A Macrocyclic Enzyme Model System. Substrate Specificity for the Inclusion into Paracyclophane Oxime and the Subsequent Acyl Transfer Reaction (1975) (20)
Development of a human mammary epithelial cell culture model for evaluation of drug transfer into milk (2006) (20)
Effects of phenolic dental medicaments on prostaglandin synthesis by microsomes of bovine tooth pulp and rabbit kidney medulla. (1988) (20)
Amplification of c-Ki-ras gene and aberrant expression of c-myc in WI-38 cells transformed in vitro by gamma-irradiation. (1985) (20)
Tumor necrosis factor (TNF) receptor-2-mediated DNA synthesis and proliferation in primary cultures of adult rat hepatocytes: The involvement of endogenous transforming growth factor-alpha. (2009) (19)
Induction of islet B-cell regeneration in partially pancreatectomized rats by poly(ADP-ribose) synthetase inhibitors (1988) (19)
The anti-inflammatory effects of phenolic dental medicaments as determined by mouse ear edema assay. (1989) (19)
Significant effects of Z-Gln-Val-Val-OME, common sequences of thiol proteinase inhibitors on thiol proteinases. (1987) (19)
Isolation and characterization of human reg protein produced in Saccharomyces cerevisiae (1990) (19)
Isolation and functional expression of pituitary peptidylglycine alpha-amidating enzyme mRNA. A variant lacking the transmembrane domain. (1990) (19)
Identification of a novel 65-kDa cell surface receptor common to pancreatic polypeptide, neuropeptide Y and peptide YY. (1990) (18)
Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells. (2003) (18)
Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca2+ signalling in rodent NG108-15 neuroblastoma cells (2007) (18)
Effects of poly (ADP-ribose) synthetase inhibitor on b-cells of a canine pancreas after massive pancreatectomy (1991) (18)
Identification of the five essential histidine residues for peptidylglycine monooxygenase. (1996) (17)
Requirement of Calmodulin- dependent Protein Kinase II in Cyclic ADP-ribose-mediated (1995) (17)
Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide‐induced microglial and astrocytic neuroinflammation by increasing NAD+ (2021) (17)
Involvement of leukocyte and glucocorticoid in the acute-phase response of angiotensinogen. (1987) (17)
Sequence-independent inhibition of RNA transcription by DNA dumbbells and other decoys. (1997) (17)
Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells. (1985) (17)
Dup 753 prevents the development of puromycin aminonucleoside-induced nephrosis. (1993) (17)
Detection of bikunin mRNA in limited portions of rat brain. (1999) (16)
Secretion of preβ HDL increases with the suppression of cholesteryl ester transfer protein in Hep G2 cells (1999) (16)
Pancreatic Regenerating Protein I in Chronic Pancreatitis and Aging: Implications for New Therapeutic Approaches to Diabetes (2008) (16)
Na(+)/H(+) exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2(+) mobilization. (2013) (16)
The CD38-Cyclic ADP-Ribose System in Mammals: Historical Background, Pathophysiology and Perspective (2014) (16)
Synthesis of preproinsulin with RNA preparation of streptozotocin‐nicotinamide induced B‐cell tumor (1977) (16)
Isolation and properties of two rat plasma T-kininogens. (1986) (16)
Identification of T-kininogen in rat urine. (1987) (16)
Cyclic ADP-ribose-mediated insulin secretion and Reg, regenerating gene (1999) (16)
Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD) (2019) (15)
HIV-1 replication is inhibited by a pseudo-substrate peptide that blocks Tat transactivation. (2000) (15)
Enhancement of Glucose‐induced Insulin Secretion in Transgenic Mice Overexpressing Human VIP Gene in Pancreatic β Cells 1 (1996) (15)
Expression of kininogen mRNAs and plasma kallikrein mRNA by cultured neurons, astrocytes and meningeal cells in the rat brain. (1999) (15)
Sexual dimorphism of urine angiotensinogen excretion in the rat. (1994) (15)
Murine fibroblasts synthesize and secrete kininogen in response to cyclic-AMP, prostaglandin E2 and tumor necrosis factor. (1995) (15)
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils. (1996) (15)
The reversibility of the adenylate cyclase reaction. (1971) (15)
Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors. (2019) (15)
Angiotensin II regulates liver regeneration via type 1 receptor following partial hepatectomy in mice. (2008) (15)
Effect of quinaldic acid and its relatives on insulin-release from isolated Langerhans islets. (1975) (14)
[57] Kynurenine 3-monooxygenase (hydroxylase) (rat liver) (1970) (14)
n-hexane-induced synthesis of hepatic metallothionein is mediated by IL-6 in mouse. (1994) (14)
Regulatory Role of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) in Insulin Secretion by Glucose in Pancreatic βCells (1995) (14)
Role of angiotensin II in the transforming growth factor-beta 1 expression of rat kidney in anti-glomerular basement membrane antiserum-induced glomerulonephritis. (1995) (14)
Lipopolysaccharide injection into the cerebral ventricle evokes kininogen induction in the rat brain (2003) (14)
S-(2-(acylamino)phenyl) 2,2-dimethylpropanethioates as CETP inhibitors. (2004) (14)
Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death (2007) (14)
Genomic organization, chromosomal localization, and promoter of human gene for FK506-binding protein 12.6. (2005) (14)
Rat fibroblasts synthesize T-kininogen in response to cyclic-AMP, prostaglandin E2 and cytokines. (1995) (13)
IP receptor agonist-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes: the involvement of endogenous transforming growth factor-alpha. (2009) (13)
Enhancement of Cell Viability in Cryopreserved Rat Vascular Grafts by Administration of Regenerating Gene (Reg) Inducers (2003) (13)
Adenylate cyclase from Brevibacterium liquefaciens. Reversibility and thermodynamic studies. (1974) (13)
Structure determination and evolution of the chicken cDNA and gene encoding prepropancreatic polypeptide. (1993) (13)
[Molecular mechanism of degeneration, oncogenesis and regeneration of pancreatic beta-cells of islets of Langerhans]. (1988) (13)
F10BINOL-derived chiral phosphoric acid-catalyzed enantioselective carbonyl-ene reaction: theoretical elucidation of stereochemical outcomes (2018) (13)
Efficient amidation of C-peptide deleted NPY precursors by non-endocrine cells is affected by the presence of Lys-Arg at the C-terminus (1993) (13)
The Photochemical Reaction of p-Benzoquinone in Water (1972) (12)
Localization of vasoactive intestinal peptide (VIP) messenger RNA (mRNA) in amacrine cells of rat retina. (1992) (12)
A novel model of insulin‐dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIα (Thr286Asp) in pancreatic β‐cells (2008) (12)
Synthetic Method for 2,2'-Disubstituted Fluorinated Binaphthyl Derivatives and Application as Chiral Source in Design of Chiral Mono-Phosphoric Acid Catalyst. (2015) (12)
Expression of Ins1 and Ins2 genes in mouse fetal liver (2014) (12)
Nucleotide sequence determination of mouse, chicken and Xenopus laevis rig cDNAs: the rig-encoded protein is extremely conserved during vertebrate evolution. (1990) (12)
Possible involvement of adenosine 3':5'-cyclic monophosphate and extracellular calcium ions in histamine stimulation of interleukin-1 release from macrophage-like P388D1 cells. (1990) (12)
A role of sulfhydryl groups in imidazoleacetate monooxygenase. (1968) (12)
Structure‐specific effects of lipidated oxytocin analogs on intracellular calcium levels, parental behavior, and oxytocin concentrations in the plasma and cerebrospinal fluid in mice (2017) (12)
Chromosomal assignment of human VIP/PHM-27 gene to 6q26----q27 region by spot blot hybridization and in situ hybridization. (1988) (11)
MARCO, a macrophage scavenger receptor highly expressed in rodents, mediates dalcetrapib-induced uptake of lipids by rat and mouse macrophages. (2010) (11)
Expression of the insulinoma gene rig during liver regeneration and in primary cultured hepatocytes. (1988) (11)
Thiol proteinase inhibitor in the ascitic fluid of sarcoma 180 tumor-bearing mice. (1987) (11)
NF-kappaB is required for CD38-mediated induction of C(gamma)1 germline transcripts in murine B lymphocytes. (2002) (11)
Cysteine proteinase inhibitor in the ascitic fluid of sarcoma 180 tumor-bearing mice is a low molecular weight kininogen. Partial NH2- and COOH-terminal sequences and susceptibility to various glandular kallikreins. (1990) (11)
Down-regulation of bradykinin B2-receptor mRNA in the heart in pressure-overload cardiac hypertrophy in the rat. (2003) (11)
Transcriptional activity of nuclei from WI‐38 cells at various passages (1980) (10)
The CD38-cyclic ADP-ribose signaling system in insulin secretion (2004) (10)
Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils. (1994) (10)
Expression of low-molecular-weight kininogen in mouse vascular smooth muscle cells. (1998) (10)
Role of the kidney in the plasma clearance of angiotensinogen in the rat: plasma clearance and tissue distribution of 125I-angiotensinogen. (1995) (10)
Orthovanadate-induced vasocontraction is mediated by the activation of Rho-kinase through Src-dependent transactivation of epidermal growth factor receptor (2014) (10)
Elevation of plasma angiotensinogen in rats with experimentally induced nephrosis. (1993) (10)
Some properties of gingival 12-lipoxygenase activity in human and dog. (1990) (10)
Stimulation of hepatic T‐kininogen production by interferon (1988) (10)
From insulin synthesis to secretion: Alternative splicing of type 2 ryanodine receptor gene is essential for insulin secretion in pancreatic β cells. (2017) (10)
Expressions of bradykinin B2-receptor, kallikrein and kininogen mRNAs in the heart are altered in pressure-overload cardiac hypertrophy in mice. (2001) (10)
Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging (2020) (9)
Na+/H+ exchanger inhibitor augments hyperosmolarity-induced vasoconstriction by enhancing actin polymerization. (2013) (9)
Expression and localization of regenerating gene I in a rat liver regeneration model. (2009) (9)
Characterization of the 5'-regulatory region of rat Reg I gene. (1994) (9)
Recent advances in physiological and pathological significance of NAD+ metabolites: roles of poly(ADP-ribose) and cyclic ADP-ribose in insulin secretion and diabetogenesis (2003) (9)
Tissue-Specific expression of rat kininogen mRNAs. (2000) (9)
Inhibition of angiotensin converting enzyme of rat brain with bradykinin and its fragments. (1981) (9)
New Aspects to the Functioning and Regeneration of Pancreatic β-Cells (1997) (9)
Anti-CD38 Autoimmunity in Children with Newly Diagnosed Type 1 Diabetes Mellitus (2005) (9)
Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca2+ mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration (2021) (8)
REG Iα protein expression in Barrett's esophagus (2008) (8)
Lipopolysaccharide activates the kallikrein–kinin system in mouse choroid plexus cell line ECPC4 (2008) (8)
Activation of the renin-angiotensin system in anti-glomerular basement membrane antibody-induced glomerulonephritis. (1995) (8)
Structural determination of Saccharomyces cerevisiae rig gene and identification of its product as ribosomal protein S21 (1992) (8)
Localization of am3 using EL Congenic Mouse Strains (2005) (8)
Labelled-calcium release from rat mandibles exposed to prostaglandins in vitro. (1983) (8)
Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice. (2009) (8)
Effect of 12-hydroxyeicosatetraenoic acid on cytosolic calcium in human neutrophils. (1994) (8)
Activation of Mitogen-Activated Protein Kinase by Hepatocyte Growth Factor Is Stimulated by Both α1- and β2-Adrenergic Agonists in Primary Cultures of Adult Rat Hepatocytes (2007) (8)
PHOTOCHEMISTRY OF 3-OXIDOPYRIDAZINIUM BETAINES ISOLATION AND REACTION OF NEW FUSED DIAZIRIDINES (1977) (8)
Localization and some properties of kynurenine-3-hydroxylase and kynurenine aminotransferase. (1971) (8)
Generation of NAADP and cADPR by Glucagon-Like Peptide-1 Evokes Ca 2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets (2008) (7)
The primary structure of rat rig/ribosomal protein S15 gene. (1992) (7)
Three-dimensional imaging of a thoracic duct cyst before thoracoscopic surgery. (2014) (7)
Studies on silyl furans. II. Halodesilylation of 2‐trimethylsilyl‐3,4‐bis(methoxycarbonyl)furans (1991) (7)
Angiotensinogen excretion in rat urine: effects of lipopolysaccharide treatment and sodium balance. (1991) (7)
p38 mitogen-activated protein kinase mediates hyperosmolarity-induced vasoconstriction through myosin light chain phosphorylation and actin polymerization in rat aorta. (2013) (7)
Loss of RegI in conjunction with gastrin deficiency in mice facilitates efficient gastric ulcer healing but is dispensable for hyperplasia and tumourigenesis (2010) (6)
Inhibition of lipoxygenase of rat dental pulp and human platelets by phenolic dental medicaments. (1990) (6)
Nicotinamide inhibits IRF-1 mRNA induction and prevents IL-1 beta-induced nitric oxide synthase expression in pancreatic beta cells. (1995) (6)
Liposomal Membranes. III. Permeation of Pyrene-labeled Lecithin into Matrix of Liposomal Bilayers (1980) (6)
A bifunctional enzyme model. Proximity effect of a functional detergent in the deacylation of p-nitrophenyl carboxylates incorporated into the macrocyclic cavity (1975) (6)
Angiotensinogen synthesis in the liver is independent of physiological estrogen levels. (1995) (6)
Endotoxin-induced enhancement of angiotensinogen synthesis in the liver: decreased response following repeated endotoxin exposure. (1993) (6)
Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate (2012) (6)
Significant effects of synthetic Gln-Val-Val-Ala-Gly and its derivatives, common sequences of thiol proteinase inhibitors, on thiol proteinase. (1985) (6)
Enzymic oxidation of reduced α-nicotinamide adenine dinucleotide (1967) (6)
Increased plasma level of T-kininogen in rats treated with Freund's adjuvant. (1986) (6)
Structure and expression of a novel rat RegIII gene. (1994) (6)
Oxytocin and CD38 in the paraventricular nucleus play a critical role in paternal aggression in mice (2020) (6)
Poly(ADP-Ribose) Synthetase Inhibitors Induce Islet B-Cell Regeneration in Partially Depancreatized Rats (1985) (6)
The CD38-Cyclic ADP-Ribose Signal System in Pancreatic ß-Cells (2002) (6)
The lipopolysaccharide-induced up-regulation of bradykinin B2-receptor in the mouse heart is mediated by tumor necrosis factor-alpha and angiotensin II. (2006) (5)
CD38 is Required for Dendritic Organization in Visual Cortex and Hippocampus (2018) (5)
Dopamine-Induced Regulation and Deregulation of the Catabolism of Cyclic ADP-Ribose, an Intrinsic mTOR Signal Inhibitor, During Development in the Rodent Striatum (2013) (5)
[108] Preparation and properties of α-NAD+ and α-NADH (1971) (5)
Detection of multiple hormones and their mRNAs in human neuroblastoma cell line NB-1 using in situ hybridization, immunocytochemistry and radioimmunoassay (1992) (5)
NMR STUDY ON THE COMPETITIVE INCLUSION OF SUBSTRATE AND DETERGENT INTO CYCLOHEPTAAMYLOSE CAVITY (1975) (5)
Abstract 1271: The Effects of Dalcetrapib on Macrophage Reverse Cholesterol Transport in a Rodent Model (2009) (5)
A sulfotransferase model: Covalent participation of a macrocyclic oxime in the hydrolysis of 2,4-dinitrophenyl sulfate (1977) (5)
Deficiency of phenylethanolamine N-methyltransferase in norepinephrine-producing pheochromocytoma (1996) (5)
Two enzymes concerned in peptide hormone alpha-amidation are synthesized from a single mRNA. (1991) (5)
[Angiotensin type 2 receptor-dependent vasodilation]. (2007) (5)
Catalysis of the deacylation of p-nitrophenyl hexadecanoate by 11-amino[20] paracyclophan-10-ol in neutral and alkaline media (1977) (5)
Fibroblasts synthesize kininogen in response to inflammatory mediators. (1996) (5)
Amino acids and peptides. XV. Synthesis of Gln-Val-Val-Ala-Gly and derivatives, a common sequence of thiol proteinase inhibitors and their effects on thiol proteinase. (2009) (5)
Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. (1984) (4)
Spontaneous bone loss in RIP-iNOS transgenic mouse: A mouse model for diabetes-mediated osteopenia/osteoporosis (2009) (4)
Secretion of prebeta HDL increases with the suppression of cholesteryl ester transfer protein in Hep G2 cells. (1999) (4)
Defects of signal transduction in a tumoral islet cell line (1990) (4)
Abstract 1092: Dalcetrapib Binds to and Changes the Conformation of CETP in a Unique Manner (Differing to That Observed With Torcetrapib) (2009) (4)
Expression of kininogen genes by rat cardiomyocytes. (1999) (4)
Synthesis of some pseudo-peptide analogs of thiol proteinase inhibitors. (1999) (4)
Amino acids and peptides. XX. Inhibition of papain by succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide, a common sequence of endogenous thiol proteinase inhibitors. (1988) (4)
Susceptibility of diabetic rat aorta to self-deactivation during prostacyclin synthesis. (1987) (4)
Energy Absorption of Distribution Line Arresters due to Lightning Back Flow Current and Ground Potential Rise for Lightning Hit to Wind Turbine Generator System (2007) (4)
Synthesis of phenyl furyl sulfides and phenyl furyl ethers by nucleophilic substitution of nitrofurans (2007) (4)
Epidermal growth factor induces Ca(2+) sensitization through Rho-kinase-dependent phosphorylation of myosin phosphatase target subunit 1 in vascular smooth muscle. (2015) (4)
12-Lipoxygenase product as an inhibitor of the action of chemoattractant peptide fMet-Leu-Phe in rat neutrophils. (1993) (4)
Inactivation of kallikrein and kininases and stabilization of whole rat brain kinin levels following focused microwave irradiation (1986) (4)
The role of AGE–RAGE system in the development of diabetic nephropathy in vivo (2002) (4)
Deletion of CD38 and supplementation of NAD+ attenuate axon degeneration in a mouse facial nerve axotomy model (2020) (3)
Gingival tissue-produced inhibition of platelet aggregation and the loss of inhibition in streptozotocin-induced diabetic rats. (1988) (3)
The Discovery and Biological Significance of a Novel Signal System in Mammalian Cells (3)
Reaction of 7-(2-mesyloxy-2-phenylethyl)theophylline with amines: Synthesis of 1,2,3,6-tetrahydro-6-imino-2-oxo-7H-purine derivatives. (2000) (3)
Role of -NADH for microsomal ethanol oxidation. (1973) (3)
Expression of m-Golsyn/Syntabulin gene during mouse brain development (2006) (3)
A Macrocyclic Enzyme Model System. Catalytic Properties of 10-Amino-[20]paracyclophane in the Deacylation of p-Nitrophenyl Carboxylates (1977) (3)
Reg (Regenerating Gene) expression by PARP and NF-kB (2003) (3)
Isolation of a cDNA Encoding Chicken Insulin Precursor (1991) (2)
Transcriptional activity of globin genes in uninducible variants of Friend leukemic cells. (1981) (2)
Prostaglandin levels in human and dog oral tissues healthy and diseased (1983) (2)
Potentiating effects of calcium chelators on basal and stimulated aldosterone production by bovine adrenal glomerulosa cells in vitro. (1997) (2)
Cyclic ADP-ribose and Inositol 1,4,5-Trisphosphate as Alternate Second Messengers for Intracellular Ca 2 1 Mobilization in Normal and Diabetic b -Cells* (1998) (2)
Inhibition of octapeptide N-myristoylation by acyl amino acids and acyl alkanolamines. (1997) (2)
Sequence of the chicken rig gene encoding ribosomal protein S15. (1991) (2)
The source of the oxygen atom in the a-hydroxyglycine intermediate of the peptidylglycine a-amidating reaction (2005) (2)
["The CD38-cyclic ADP-ribose signal system": molecular mechanism and biological significance]. (1999) (2)
INDUCTION OF REG GENE EXPRESSION, IN VITRO, IN HUMAN ISLETS: 0126 (2003) (2)
Acute-phase response of angiotensinogen in rat adjuvant arthritis. (1989) (2)
Enhancement of potassium-, and angiotensin II-stimulated aldosterone production by the calcium chelator EGTA in bovine adrenal glomerulosa cells in vitro (1997) (2)
Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes. (2007) (2)
[Pancreatic beta-cell death, regeneration and functioning]. (2003) (2)
Difference in Genetic Expression between Normal and Transfomed WI-38 Cells (1981) (1)
New aspects to the functioning and regeneration of pancreatic beta-cells. Cyclic ADP-ribose and Reg gene. (1997) (1)
T-kininogen as an acute phase reactant identical with plasma thiol proteinase inhibitor in rat adjuvant arthritis. (1986) (1)
Transcription of globin genes in murine erythroleukemic cell chromatin by RNA polymerase II from mouse cells. (1981) (1)
Complex Magnetic Behavior in the PrSr3 (Fe1-xCox)3O10-δ n = 3 Ruddlesden—Popper-Type Solid Solution with High Valent Cobalt and Iron. (2014) (1)
Transgenic Mice Overexpressing Type 2 Nitric-oxide Synthase in Pancreatic b Cells Develop Insulin-dependent Diabetes without (1998) (1)
Diurnal variation of vasoactive intestinal peptide (VIP) MRNA in the rat suprachiasmatic nucleus (1990) (1)
Involvement of inflammatory leukocytes in hepatic induction of T-kininogen in rat (1987) (1)
[Two enzymes concerned in peptide hormone alpha-amidation are synthesized from a single mRNA]. (1991) (1)
[Effect of weightlessness simulation on skeletal muscle histochemistry and bone metabolism of spontaneously hypertensive rats]. (1995) (1)
BMI and body dissatisfaction values in Japanese male and female university students:—Difference in body images according to shilhouette chart— (2017) (1)
CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice (2013) (1)
Rapid Publications Amelioration of Diabetes Mel I it us in Partially Depancreatized Rats by Poly(ADP-ribose) Synthetase Inhibitors Evidence of Islet B-Cell Regeneration (1984) (1)
Spaceflight and Biohistochemical Alterations of Antigravity Soleus Musclein Spontaneously Hypertensive Rats (SHR) to Dietary Low and High-Calcium Intake (2016) (1)
Synthesis of 6,21-dioxo-5,22-diaza[10.10]paracyclophane and its structural characteristics (1981) (1)
Crystal Structure of the Monoclinic and Cubic Polymorphs of BiMn7O12. (2010) (1)
POSTNATAL CHANGES IN THE INTENSITY OF IMMUNOHISTOCHEMICAL REACTION TO ANDROGEN RECEPTOR ANTIBODY IN MOUSE MASSETER MUSCLE (1994) (1)
Structure and Expression of Human Vasoactive Intestinal Peptide/PHM-27 Gene (1987) (1)
Expression of low-molecular-weight kininogen mRNA in human fibroblast WI38 cells. (1996) (1)
Specific inducibility of globin mRNA in Friend leukemia cells in low serum concentration. (1980) (1)
Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization (1980) (1)
Amino acids and peptides. XVII. Synthesis of a tridecapeptide corresponding to the sequence 165-177 of T-kininogen (tryptic peptide) containing Gln-Val-Val-Ala-Gly sequence and the relationship between structure and effect on thiol proteinase. (1987) (1)
Isolation and functional expression of pituitary peptidylglycine α‐amidating enzyme mRNA (2001) (1)
Degeneration, oncogenesis and regeneration of pancreatic beta-cells of islets of Langerhans. (1988) (1)
Ca2+ release by cyclic ADP ribose in rat cerebral cortex microsomes (1994) (0)
[reg (regenerating gene) : structure and tissue specific expression]. (1991) (0)
Comprar Molecular Biology of the Islets of Langerhans | Hiroshi Okamoto | 9780521088008 | Cambridge University Press (2008) (0)
Platelet-activating factor-induced intracellular calcium mobilization in neutrophils and the role of protein kinase C (1993) (0)
With 2-Kidney , 1-Clip Hypertension Mediated Phosphorylation of eNOS in the Aortas of Mice − Angiotensin Type 2 Receptor (2005) (0)
Stimulation by carrageenan of arachidonate 12-lipoxygenase activity in dog gingival tissue. (1991) (0)
The R140T mutation on the CD38 gene in type 2 diabetes (2000) (0)
Effect of estradiol on prostaglandin synthesis in dog gingiva.:Effect of estradiol on prostaglandin synthesis in dog gingiva (1984) (0)
Two store-operated Ca2+ influxes with differential sensitivities to Zn2+ in mouse salivary gland acinar cells. (2005) (0)
Leukocyte-induced regulation of hepatic production of T-kininogen. (1989) (0)
Erratum to “NAD+‐glycohydrolase from Streptococcus pyogenes shows cyclic ADP‐ribose forming activity” [FEMS Microbiology Letters 130 (1995) 201–204] (1995) (0)
Abstract 23016: Dalcetrapib Mediated Increase in Macrophage Reverse Cholesterol Transport Does Not Correlate with Raised HDL-C in Hamsters (2010) (0)
Diurnal variation of vasoactive intestinal peptide (VIP) messenger RNA (mRNA) in the rat suprachiasmatic nucleus (SCN). (1990) (0)
Molecular Biology of the Islets of Langerhans: Introductory overview by HIROSHI OKAMOTO (1990) (0)
Trans-activation byhumanimmunodeficiency virusTatprotein requires theC-terminal domainofRNA polymerase II (1996) (0)
Characterization of capacitative calcium entry in submandibular gland acinar cells (2004) (0)
Increased uptake of T-kininogen by the liver in inflammatory conditions. (1992) (0)
Differential Upregulation of Ca^ Cycling-Related Proteins May Explain the Gender Difference in Hypertrophic Response in CD38 Knockout Mice (2003) (0)
The CD38-cyclic ADP-ribose signal system, a paradigm for Ca2+-signaling (2004) (0)
Regeneration of Islet β-cells by Reg (Regenerating Gene): Transcriptional activation of Reg gene and identification of reg protein receptor (2000) (0)
Abstract MP06: The Protein Tyrosine Phosphatase Inhibitors Induce The Vasoconstriction Via Src/epidermal growth factor/rho-kinase Cascade (2014) (0)
Catalytic Efficiency of [20]Paracyclophane Oxime and Cycloheptaamylose in the Decomposition of Carboxylate and Carbonate Esters (1981) (0)
[Structure and biological function of Reg genes and Reg proteins]. (1997) (0)
Molecular Biology of the Islets of Langerhans: Preface by HIROSHI OKAMOTO (1990) (0)
Elevation of plasma angiotensinogen in rats with experimentally induced nephrosis (1992) (0)
1P-0162 Advanced glycation endproducts and RAGE have a central role in the development of diabetic vascular complications (2003) (0)
Reg 1 expression in regenerating skeletal muscle in rat (2007) (0)
Kininogen in tumor-bearing mice. (1989) (0)
Inhibitory effect of various calcitonins on prostaglandin stimulated resorption of mandibula (1979) (0)
Studies on the effects of bradykinin and its fragments on the central nervous system. (1979) (0)
1P-0153 Chronic exposure to high glucose accelerates monocyte chemoattractant protein-1 production through activation of p38 mitogen-activated protein kinase in human vascular endothelial cells (2003) (0)
[Vasoactive intestinal polypeptide(VIP)- and insulin-producing cells--molecular biology, physiology and pathology]. (1984) (0)
Poly(adp-ribose) synthetase inhibitors also induce islet b-cell regeneration (1984) (0)
Transplantation of preserved pancreatic islets into the portal vein of rats (1978) (0)
Amino acids and peptides. XXVIII. Preparation of poly(ethylene glycol) hybrids of Gln-Val-Val-Ala-Gly analogs and their inhibitory effect on papain. (1996) (0)
Advanced Glycation End Products Ligation Septic Shock Is Associated with Receptor for Yonekura and (2011) (0)
[Structure and expression of rig]. (1991) (0)
High Glucose Accelerates Monocyte Chemoattractant Protein-1 Production by Sequential Activation of p38 Mitogen-Activated Protein Kinase in Human Vascular Endothelial Cells (2003) (0)
Role of the kidney in the plasma clearance of anoiotensinogen in the rat. (1996) (0)
Studies on Silyl Furans. Part 2. Halodesilylation of 2-Trimethylsilyl- 3,4-bis(methoxycarbonyl)furans. (1991) (0)
CATALYSIS OF THE DEACYLATION OF P-NITROPHENYL HEXADECANOATE BY 11-AMINO(20)PARACYCLOPHAN-10-OL IN NEUTRAL AND ALKALINE MEDIA (1977) (0)
IP receptor agonist-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes : possible involvement of endogenous transforming growth factor-α (2011) (0)
Syntheses of Various Hydrophobic Substrates for Enzyme Model Kinetics (1977) (0)
3P-0680 Histone deacetylase inhibitor (trichostatin A) inhibits vascular smooth muscle cells proliferation via upregulation of cyclin dependent kinase inhibitor p21waf1 (2003) (0)
Synthesis of Phenyl Furyl Sulfides and Phenyl Furyl Ethers by Nucleophilic Substitution of Nitrofurans. (2008) (0)
BORN TURNOVER IN ELITE RHYTHMIC SPORTS GYMNASTS 569 (1997) (0)
THE EFFECT OF INCREASED CALCIUM SUPPLEMENTATION AND EXERCISE TRAINING ON BONE TURNOVER IN RATS. (1998) (0)
539 FIBER TYPE CONVERSION OF ENDUARANCE TRAINED ALTITUDE-BORN AND SEA LEVEL-BORN RATS (1994) (0)
MITOCHONDRIAL VOLUME DENSITY AND SDH ENZYME ACTIVITY IN SKELETAL MUSCLE FOLLOWING TRAINING AND INCREASED CALCIUM INTAKE (1998) (0)
SUCCINATE DEHYRDOGENASE ACTIVITY IN SIZE AND REGION OF SINGLE MUSCLE FIBER FOLLOWING BODY SUSPENSION: 22 (1995) (0)
[Inhibitory effect of running exercise on age-induced muscle atrophy]. (1994) (0)
EFFECTS OF HYPOXIC EXPOSURE AND ENDURANCE EXERCISE TRAINING ON THE OXIDATIVE POTENTIALS OF SOLEUS MUSCLE FIBERS AND MOTONEURONS IN THE RAT (1993) (0)
HISTOCHEMICAL AND STRUCTURAL ADAPTATION OF SKELETAL MUSCLE TO BODY SUSPENSION IN SPONTANEOUSLY HYPERTENSIVE RATS.: 1024 (1995) (0)
The Comparison of Oxidative Enzyme Activity in Skeletal Muscle from Stroke-Prone Spontaneously Hypertensive and Normotensive Rats (1996) (0)
ADAPTATION TO ENVIRONMENTAL CHANGES: CONDITIONS OF SEA LEVEL TO ALTITUDE AND ALTITUDE TO SEA LEVEL 1210 (1996) (0)
STEREOLOGICAL ANALYSIS OF SOLEUS MUSCLE FOLLOWING CALCIUM ADMINISTRATION AND EXERCISE 1323 (1997) (0)
THE OXIDATIVE ENZYME ACTIVITY IN SKELETAL MUSCLE FROM STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE RATS 360 (1996) (0)
SYNTHESIS OF 6,21-DIOXO-5,22-DIAZA(10.10)PARACYCLOPHANE AND ITS STRUCTURAL CHARACTERISTICS (1982) (0)
Effect of 1,6-dihydro-2[2-(2-methylpropoxy)anilino]-6-oxo-5-pyrimidineca rboxyli c acid on ethanol-induced microvascular injury in rats. (1996) (0)
Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex (2021) (0)
Development of reversible inhibitors against thiol proteinases and studies on the binding mode of the inhibitor with papain (1993) (0)
■ Graduate Schools / Undergraduate Schools (2007) (0)
PHOTOCHEMICAL REACTIONS. XVIII. PHOTOCHEMISTRY OF 3-OXIDOPYRIDAZINIUM BETAINES. ISOLATION AND REACTION OF NEW FUSED DIAZIRIDINES (1978) (0)
Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced neuroinflammation in the hippocampus (2020) (0)
Amino acids and peptides. XLIV. Synthesis of stereoisomeric pentapeptides of thiol proteinase inhibitor. (1996) (0)
Bis(2‐(acylamino)phenyl) Disulfides, 2‐(Acylamino)benzenethiols, and S‐(2‐(Acylamino)phenyl) Alkanethioates as Novel Inhibitors of Cholesteryl Ester Transfer Protein (CETP). (2000) (0)
Expression of Ins1 and Ins2 genes in mouse fetal liver (2013) (0)
A Bifunctional Catalysis of Ester Hydrolysis as Promoted by Cooperation of Functional Macrocycle and Functional Detergent (1980) (0)
Isolation and characterization of the human homologue of rig and its pseudogenes: The functional gene has features characteristic (0)
Technical Comments (2020) (0)
Combinaison comprenant du s-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]2-methylpropanethioate et un inhibiteur de hmg coa reductase (2004) (0)
Response : Cyclic ADP-Ribose in β Cells (1993) (0)
Photochemistry of Pyridazine Betaines. (1976) (0)
The Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice: a novel mouse model of severe insulin-dependent diabetes (2014) (0)
Amino acids and peptides. XXXIX. Synthesis of iNoc-Gln-Val-Val-Ala-Ala-pNA and its action on thiol proteinases. (1995) (0)
Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate (2012) (0)
S‐(2‐(Acylamino)phenyl) 2,2‐Dimethylpropanethioates as CETP Inhibitors. (2004) (0)
A Facile Solid-Phase Synthesis of Peptide ρ-Nitroanilide Analogs (2000) (0)
Arachidonic acid metabolism and antiseptics (1990) (0)
Study on 12-hydroxyeicosatetraenoic acid (12-HETE) -induced intracellular calcium elevation in rabbit neutrophils (1993) (0)

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