Hiroshi Sakagami
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Computer Science
Hiroshi Sakagami's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Hiroshi Sakagami's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
- Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. (1981) (986)
- Production of bioactive triterpenes by Eriobotrya japonica calli. (2002) (269)
- Antioxidant and prooxidant action of eugenol-related compounds and their cytotoxicity. (2002) (256)
- 3,5-dibenzoyl-1,4-dihydropyridines: synthesis and MDR reversal in tumor cells. (2002) (177)
- Inhibition of herpes simplex virus infection by tannins and related compounds. (1989) (165)
- Cytotoxic flavonoids with isoprenoid groups from Morus mongolica. (2001) (160)
- Radical scavenging activity and cytotoxicity of ferulic acid. (2002) (137)
- ACE2: The Key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel? (2020) (135)
- Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). (2003) (133)
- Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra. (2003) (132)
- Polyphenols from Eriobotrya japonica and their cytotoxicity against human oral tumor cell lines. (2000) (125)
- Cytotoxic activity of hydrolyzable tannins against human oral tumor cell lines--a possible mechanism. (2000) (124)
- Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids. (2005) (121)
- Apoptosis-inducing activity of vitamin C and vitamin K. (2000) (119)
- The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF. (2000) (116)
- Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass ionomer cement (2015) (115)
- Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts. (2002) (107)
- Antitumor potential and possible targets of phenothiazine-related compounds. (2000) (105)
- Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides (2016) (103)
- Distribution of lignin-carbohydrate complex in plant kingdom and its functionality as alternative medicine. (2010) (100)
- Antinephritis and radical scavenging activity of prenylflavonoids. (2003) (100)
- Prooxidant action of two antioxidants: ascorbic acid and gallic acid. (1997) (99)
- Biological activity of persimmon (Diospyros kaki) peel extracts (2003) (97)
- Induction of cytotoxicity by chlorogenic acid in human oral tumor cell lines. (2000) (96)
- Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity. (2019) (91)
- Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells. (2008) (91)
- Modulating factors of radical intensity and cytotoxic activity of ascorbate (review). (1997) (91)
- New diarylheptanoids and diarylheptanoid glucosides from the rhizomes of Tacca chantrieri and their cytotoxic activity. (2002) (90)
- Non-targeted metabolite profiling in activated macrophage secretion (2012) (89)
- Hormetic and anti-radiation effects of tropolone-related compounds. (2010) (82)
- New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors. (2018) (81)
- Cytotoxic potential of phenothiazines. (2006) (78)
- Endonuclease activity and induction of DNA fragmentation in human myelogenous leukemic cell lines. (1995) (77)
- Cytotoxicity and apoptosis-inducing activity of bisphenol A and hydroquinone in HL-60 cells. (2005) (76)
- Cytotoxic and DNA damage-inducing activities of low molecular weight phenols from rhubarb. (2001) (75)
- Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants. (2001) (73)
- Biological activity of barbados cherry (acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions (2004) (70)
- Antiviral and Antitumor Activity of Licorice Root Extracts. (2016) (69)
- Triterpene glycosides from the roots of Sanguisorba officinalis. (2001) (69)
- Anti-HIV (human immunodeficiency virus) activity of sulfated paramylon. (1993) (68)
- Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines. (2004) (68)
- Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines. (2000) (66)
- Relationship between ascorbyl radical intensity and apoptosis-inducing activity. (1996) (66)
- Coumarin derivatives with tumor-specific cytotoxicity and multidrug resistance reversal activity. (2005) (66)
- Induction of apoptosis by flavones, flavonols (3-hydroxyflavones) and isoprenoid-substituted flavonoids in human oral tumor cell lines. (2000) (65)
- Benzophenones and xanthones with isoprenoid groups from Cudrania cochinchinensis. (2001) (63)
- Modification of human immunodeficiency viral replication by pine cone extracts. (1990) (62)
- Cycloartane glycosides from the rhizomes of Cimicifuga racemosa and their cytotoxic activities. (2002) (62)
- Molecular requirements of lignin-carbohydrate complexes for expression of unique biological activities. (2005) (62)
- Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity. (2001) (60)
- Bufadienolide and spirostanol glycosides from the rhizomes of helleborusorientalis. (2003) (59)
- Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds. (2005) (58)
- Induction of apoptosis by morphine in human tumor cell lines in vitro. (2007) (56)
- Prevention of oral diseases by polyphenols (review). (1999) (55)
- Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells. (2008) (55)
- The redox state of glutathione regulates the hypoxic induction of HIF-1. (2009) (55)
- New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones. (2018) (54)
- EGF‐stimulated signaling by means of PI3K, PLCγ1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland (2003) (54)
- Tumor-specificity and type of cell death induced by trihaloacetylazulenes in human tumor cell lines. (2007) (53)
- Biological activity of feijoa peel extracts. (2000) (53)
- The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones. (2009) (53)
- Possible Link between Glycolysis and Apoptosis Induced by Sodium Fluoride (2005) (52)
- In vitro biological activity of prenylflavanones. (2001) (52)
- Platelet-derived growth factor exerts disparate effects on odontoblast differentiation depending on the dimers in rat dental pulp cells (2004) (51)
- Alteration of metabolomic profiles by titanium dioxide nanoparticles in human gingivitis model. (2015) (51)
- Hypoxia and reoxygenation augment bone-resorbing factor production from human periodontal ligament cells. (2007) (51)
- Induction of DNA fragmentation by tannin- and lignin-related substances. (1995) (49)
- Effect of metal ions on radical intensity and cytotoxic activity of ascorbate. (1997) (49)
- Possible role of radical intensity and oxidation potential for gallic acid-induced apoptosis. (1997) (49)
- Induction of Apoptosis by β-Diketones in Human Tumor Cells (2004) (49)
- Steroidal glycosides from the leaves of Cestrum nocturnum. (2002) (48)
- Cytotoxicity and radical intensity of eugenol, isoeugenol or related dimers. (2000) (48)
- Antitumor activity of polysaccharide fractions from pine cone extract of Pinus parviflora Sieb. et Zucc. (1987) (45)
- Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines (2016) (44)
- Cytotoxic activity of vitamins K1, K2 and K3 against human oral tumor cell lines. (2001) (44)
- Selective antibacterial and apoptosis-modulating activities of mastic. (2009) (44)
- Induction of Apoptosis in Human Oral Keratinocyte by Doxorubicin. (2017) (44)
- Tumor-specific cytotoxicity and apoptosis-inducing activity of berberines. (2005) (43)
- Inhibition of influenza virus infection by pine cone antitumor substances. (1990) (43)
- Cell death induced by nutritional starvation in mouse macrophage-like RAW264.7 cells. (2009) (43)
- Lignified materials as medicinal resources. V. Anti-HIV (human immunodeficiency virus) activity of some synthetic lignins. (1992) (43)
- Antimicrobial activity of trifluoromethyl ketones and their synergism with promethazine. (2001) (42)
- Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases (2016) (42)
- Effects of 3-styrylchromones on metabolic profiles and cell death in oral squamous cell carcinoma cells (2015) (42)
- Structure-Activity Relationships of α, β-Unsaturated Ketones as Assessed by their Cytotoxicity against Oral Tumor Cells (2004) (41)
- Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors. (2019) (41)
- Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities (2016) (41)
- Antiviral, antibacterial and vitamin C-synergized radical-scavenging activity of Sasa senanensis Rehder extract. (2008) (40)
- 3-Arylidene-1-(4-nitrophenylmethylene)-3,4-dihydro-1H-naphthalen-2-ones and related compounds displaying selective toxicity and reversal of multidrug resistance in neoplastic cells. (2005) (40)
- New phenolic Mannich bases with piperazines and their bioactivities. (2019) (40)
- Inhibition by Porphyromonas gingivalis LPS of apoptosis induction in human peripheral blood polymorphonuclear leukocytes. (1998) (39)
- Selective cytotoxic activity of grape peel and seed extracts against oral tumor cell lines. (2000) (39)
- Biological activity of carotenoids in red paprika, Valencia orange and Golden delicious apple (2005) (39)
- 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy. (2010) (38)
- Novel inhibitors of poly(ADP-ribose) glycohydrolase. (1993) (38)
- Hydrolyzable tannins of tamaricaceous plants. III. Hellinoyl- and macrocyclic-type ellagitannins from Tamarix nilotica. (2010) (38)
- Plasma pteridine concentrations in patients with chronic renal failure. (2002) (38)
- Biological activity of 3-formylchromones and related compounds. (2007) (38)
- Biological activities and possible dental application of three major groups of polyphenols. (2014) (37)
- Induction of tumor-specific cytotoxicity and apoptosis by doxorubicin. (2005) (37)
- Triterpene glycosides from the whole plant of Anemone hupehensis var. japonica and their cytotoxic activity. (2009) (37)
- A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus. (2009) (36)
- Inhibition of herpes simplex virus infection by pine cone antitumor substances. (1989) (36)
- Structure-cytotoxic activity relationships of simple hydroxylated coumarins. (2003) (36)
- Re-evaluation of anti-inflammatory activity of mastic using activated macrophages. (2009) (36)
- Cytotoxic activity of benzothiepins against human oral tumor cell lines. (2001) (36)
- Changes in fluoride sensitivity during in vitro senescence of normal human oral cells. (2005) (36)
- Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol (2016) (36)
- Microwave-assisted synthesis and bioevaluation of new sulfonamides (2017) (36)
- Radical intensity and cytotoxic activity of curcumin and gallic acid. (1998) (36)
- Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides (2016) (35)
- Inhibition of NO production by activated macrophages by phenolcarboxylic acid monomers and polymers with radical scavenging activity. (2003) (35)
- Tumor-specific cytotoxicity of 3,5-dibenzoyl-1,4-dihydropyridines. (2005) (35)
- Synergistic cytotoxic action of vitamin C and vitamin K3. (2001) (34)
- Induction of antimicrobial activity by antitumor substances from pine cone extract of Pinus parviflora Sieb. et Zucc. (1988) (34)
- Cytotoxic activity of azulenes against human oral tumor cell lines. (2003) (34)
- Age-related decline in histone H1 fraction in human diploid fibroblast cultures. (1980) (34)
- Radical generation, radical-scavenging activity, and cytotoxicity of eugenol-related compounds. (2000) (33)
- Three new flavonoids, proanthocyanidin, and accompanying phenolic constituents from Feijoa sellowiana (2018) (33)
- Anti-HIV and vitamin C-synergized radical scavenging activity of cacao husk lignin fractions. (2008) (33)
- Quest for anti-inflammatory substances using IL-1β-stimulated gingival fibroblasts. (2011) (33)
- Effect of antioxidants on radical intensity and cytotoxic activity of eugenol. (1998) (32)
- Clinicopathological evaluation of repeated courses of intravesical bacillus Calmette-Guerin instillation for preventing recurrence of initially resistant superficial bladder cancer. (1996) (32)
- Antimicrobial activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines. (1992) (32)
- 1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins (2013) (32)
- Steroidal glycosides from the bulbs of Ornithogalum thyrsoides. (2004) (32)
- Possible involvement of lignin structure in anti-influenza virus activity. (1991) (32)
- Anti-stress, anti-HIV and vitamin C-synergized radical scavenging activity of mulberry juice fractions. (2007) (32)
- Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties. (2012) (31)
- Biological activity of luteolin glycosides and tricin from Sasa senanensis Rehder. (2011) (31)
- Effect of Trolox, a synthetic analog of alpha-tocopherol, on cytotoxicity induced by UV irradiation and antioxidants. (1997) (31)
- Copper, but not iron, enhances apoptosis-inducing activity of antioxidants. (1997) (31)
- Prominent Anti-UV Activity and Possible Cosmetic Potential of Lignin-carbohydrate Complex. (2016) (31)
- Re-evaluation of anti-inflammatory potential of eugenol in IL-1β-stimulated gingival fibroblast and pulp cells. (2013) (31)
- Serum Calcium-decreasing Factor, Caldecrin, Inhibits Osteoclast Differentiation by Suppression of NFATc1 Activity* (2010) (31)
- Biological activity of kiwifruit peel extracts (2001) (31)
- Anti-influenza virus activity of a lignin fraction from cone of Pinus parviflora Sieb. et Zucc. (1992) (30)
- Cytotoxicity and differentiation-inducing activity of phenothiazine and benzo[a]phenothiazine derivatives. (1991) (30)
- Antitumor potential of three herbal extracts against human oral squamous cell lines. (2009) (30)
- Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity (2010) (30)
- Induction of cell death by ascorbic acid derivatives in human renal carcinoma and glioblastoma cell lines. (1999) (30)
- Anti-stress activity of mulberry juice in mice. (2006) (30)
- 3-(3,4,5-Trimethoxyphenyl)-1-oxo-2-propene: a novel pharmacophore displaying potent multidrug resistance reversal and selective cytotoxicity. (2007) (30)
- Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives (2015) (30)
- Chemical constituents of the bulbs of Habranthus brachyandrus and their cytotoxic activities. (2009) (30)
- Cell death-inducing activity of opiates in human oral tumor cell lines. (2002) (30)
- Late Phase Allergic Reaction to a CT Contrast Medium (Iotrolan) (1991) (29)
- Changes in salivary amino acid composition during aging. (2010) (29)
- Quantitative structure-cytotoxicity relationship analysis of betulinic acid and its derivatives by semi-empirical molecular-orbital method. (2005) (29)
- Induction of non-apoptotic cell death by morphinone in human promyelocytic leukemia HL-60 cells. (2006) (29)
- Apoptosis-inducing activity of cisplatin (CDDP) against human hepatoma and oral squamous cell carcinoma cell lines. (2004) (29)
- Benzylideneascorbate induces apoptosis in L929 tumor cells. (1993) (28)
- Cytotoxic activity of styrylchromones against human tumor cell lines. (2005) (28)
- Effects of Catuaba extracts on microbial and HIV infection. (1992) (28)
- The requirement for and mobilization of calcium during induction by sodium ascorbate and by hydrogen peroxide of cell death. (1996) (28)
- Anti-HIV and immunomodulation activities of cacao mass lignin-carbohydrate complex. (2011) (28)
- Type of cell death induced by various metal cations in cultured human gingival fibroblasts. (2010) (28)
- Induction of apoptosis by cooperative action of vitamins C and E. (1998) (28)
- Radical scavenging activity of Acer nikoense Maxim. extract. (1998) (28)
- Effects of TiO2 nano glass ionomer cements against normal and cancer oral cells. (2014) (28)
- Cytotoxic activity of steroidal saponins against human oral tumor cell lines. (2000) (28)
- Steroidal glycosides from the bulbs of Camassia leichtlinii and their cytotoxic activities. (2001) (27)
- Molecular species of the antitumor and antiviral fraction from pine cone extract. (1989) (27)
- Antimicrobial spectrum of lignin-related pine cone extracts of Pinus parviflora Sieb. et Zucc. (1990) (27)
- Induction of apoptosis by epigallocatechin gallate and autophagy inhibitors in a mouse macrophage-like cell line. (2008) (27)
- Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure. (2013) (27)
- Computerized tomography in acute pyelonephritis: the clinical correlations. (1990) (26)
- Type of cell death induced by seven metals in cultured mouse osteoblastic cells. (2010) (26)
- Antioxidative activity of Allium victorialis L. extracts. (2001) (26)
- Inhibition of chlorogenic acid-induced cytotoxicity by CoCl2. (2001) (26)
- Re-evaluation of cytotoxicity and iron chelation activity of three beta-diketones by semiempirical molecular orbital method. (2005) (26)
- α-Trifluoromethylated acyloins induce apoptosis in human oral tumor cell lines (1999) (26)
- Radical modulation activity of lignins from a mangrove plant, Ceriops decandra (Griff.) Ding Hou. (1998) (26)
- Stimulation of human monocyte and polymorphonuclear cell iodination and interleukin‐1 production by epigallocatechin gallate (1992) (26)
- Cytotoxic activity of tropolones against human oral tumor cell lines. (2003) (26)
- Synthesis and biological activity of N-acylphenothiazines. (2000) (25)
- Cytotoxicity and type of cell death induced by local anesthetics in human oral normal and tumor cells. (2012) (25)
- Antitumor activity of benzo[a]phenothiazines. (1999) (25)
- Diverse biological activities of moxa extract and smoke. (2001) (25)
- Effect of Sasa senanensis Rehder extract on NO and PGE2 production by activated mouse macrophage-like RAW264.7 cells. (2009) (25)
- 3,5-diacetyl-1,4-dihydropyridines: synthesis and MDR reversal in tumor cells. (2000) (25)
- Effect of glutathione-modulating compounds on hydrogen-peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines (1997) (25)
- Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder. (2010) (25)
- Diverse biological activities of healthy foods. (2001) (25)
- Tumor-specific cytotoxicity and type of cell death induced by benzaldehyde. (2010) (24)
- Anti-UV activity of lignin-carbohydrate complex and related compounds. (2013) (24)
- 2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance. (2009) (24)
- Interaction between eugenol-related compounds and radicals. (1998) (24)
- Bimodal effect of glycyrrhizin on macrophage nitric oxide and prostaglandin E2 production. (2008) (24)
- Hormetic and UV-protective effects of azulene-related compounds. (2011) (24)
- Re-evaluation of tumor-specific cytotoxicity of mitomycin C, bleomycin and peplomycin. (2006) (24)
- Changes of metabolic profiles in an oral squamous cell carcinoma cell line induced by eugenol. (2013) (23)
- Cytotoxic and multidrug resistance reversal activity of a vegetable, ‘Anastasia Red’, a variety of sweet pepper (2003) (23)
- Application of semiempirical method to estimate the cytotoxic activity of gallic acid and its related compounds. (2003) (23)
- Search of new cytotoxic crude materials against human oral squamous cell carcinoma using 1H NMR-based metabolomics. (2014) (23)
- Induction of apoptosis and anti-HIV activity by tannin- and lignin-related substances. (1999) (23)
- Stimulation by epigallocatechin gallate of interleukin-1 production by human peripheral blood mononuclear cells. (1995) (23)
- Factors that Affect the Type of Cell Death Induced by Chemicals (2007) (23)
- Anti-UV/HIV activity of Kampo medicines and constituent plant extracts. (2012) (23)
- Diverse biological activities displayed by phenothiazines, benzo[a]phenothiazines and benz[c]acridins (review). (1993) (23)
- Selective toxicity and type of cell death induced by various natural and synthetic compounds in oral squamous cell carcinoma. (2007) (23)
- 3,5-Bis(benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]piperidin-4-ones: a novel cluster of potent tumor-selective cytotoxins. (2011) (23)
- Effect on an iron-chelator on ascorbate-induced cytotoxicity. (1997) (23)
- Carotenoid composition and in vitro pharmacological activity of rose hips. (2012) (23)
- Induction of early apoptosis marker by morphine in human lung and breast carcinoma cell lines. (2003) (22)
- Chemical Constituents of Lycoris albiflora and their Cytotoxic Activities (2011) (22)
- Anti-UV activity of Lentinus edodes mycelia extract (LEM). (2011) (22)
- Decrease of transferrin receptor during mouse myeloid leukemia (M1) cell differentiation. (1982) (22)
- Cytotoxicity and radical modulating activity of Moxa smoke. (2005) (21)
- Anti-UV Activity of Alkaline Extract of the Leaves of Sasa senanensis Rehder. (2011) (21)
- Quantitative structure-cytotoxicity relationship of 3-styrylchromones. (2014) (21)
- Biological activity of a fruit vegetable, "Anastasia green", a species of sweet pepper. (2001) (21)
- Diurnal changes in salivary amino acid concentrations. (2010) (21)
- Lignin-like activity of Lentinus edodes mycelia extract (LEM). (2010) (21)
- Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by tropolones. (2004) (21)
- Tumour-specific cytotoxicity and MDR-reversal activity of dihydropyridines. (2006) (21)
- Effect of lignins and their precursors on nitric oxide, citrulline and asparagine production by mouse macrophage-like Raw 264.7 cells. (2002) (21)
- Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides. (2021) (21)
- Hydrolyzable tannins of tamaricaceous plants. V. Structures of monomeric-trimeric tannins and cytotoxicity of macrocyclic-type tannins isolated from Tamarix nilotica (1). (2013) (21)
- Interaction between sodium ascorbate and polyphenols. (1999) (21)
- The Chemistry of Bioactive Mesoionic Heterocycles (2007) (21)
- Comparative Analysis of Apoptosis-inducing Activity of Codeine and Codeinone (2003) (21)
- Ascorbyl radical scavenging activity of polyphenols. (1996) (20)
- Effect of anticancer drugs, metals and antioxidants on cytotoxic activity of epigallocatechin gallate. (1999) (20)
- Radical modulating activity and cytotoxic activity of synthesized eugenol-related compounds. (2000) (20)
- Cytotoxic activity of saponins from Camassia leichtlinii against human oral tumor cell lines. (2001) (20)
- Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. (2019) (20)
- Serum Calcium-decreasing Factor, Caldecrin, Inhibits Receptor Activator of NF-κB Ligand (RANKL)-mediated Ca2+ Signaling and Actin Ring Formation in Mature Osteoclasts via Suppression of Src Signaling Pathway* (2012) (20)
- A New Method for Testing Filtration Efficiency of Mask Materials Under Sneeze-like Pressure. (2020) (20)
- Hydroquinone-induced apoptosis in HL-60 cells. (2005) (20)
- Anthocyanins as Functional Food Colors (2009) (20)
- Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by azulenes. (2004) (20)
- Tetrahydrobiopterin impairs the action of endothelial nitric oxide via superoxide derived from platelets (2000) (20)
- Failure of Vitamin E to Extend the Life Span of a Human Diploid Cell Line in Culture (1977) (20)
- Negative regulation of NaF-induced apoptosis by Bad-CAII complex. (2011) (20)
- Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44 (2016) (20)
- Quantitative Structure-Cytotoxicity Relationship of 3-Styryl-2H-chromenes. (2015) (20)
- Bulbinelonesides A-E, phenylanthraquinone glycosides from the roots of Bulbinella floribunda. (2003) (20)
- O2- scavenging activity of lignins, tannins and PSK. (1992) (20)
- Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. (2009) (19)
- Amurensiosides A–K, 11 new pregnane glycosides from the roots of Adonis amurensis (2010) (19)
- Rhinacanthin C Inhibits Osteoclast Differentiation and Bone Resorption: Roles of TRAF6/TAK1/MAPKs/NF-κB/NFATc1 Signaling (2015) (19)
- Anti-influenza virus activity of synthetically polymerized phenylpropenoids. (1990) (19)
- Cytotoxic Components Against Human Oral Squamous Cell Carcinoma Isolated from Andrographis paniculata. (2016) (19)
- Radical modulation activity of pine cone extracts of Pinus elliottii var. Elliottii. (1999) (19)
- Amino acid utilization during cell growth and apoptosis induction. (1998) (19)
- Comparative study of biological activity of three commercial products of Sasa senanensis Rehder leaf extract. (2012) (19)
- Novel Polyoxygenated Spirostanol Glycosides from the Rhizomes of Helleborus orientalis (2003) (19)
- Role of hydrogen peroxide in cytotoxicity induction by ascorbates and other redox compounds. (1998) (19)
- Synthesis of some acrylophenones with N-methylpiperazine and evaluation of their cytotoxicities (2016) (19)
- Induction of prostaglandin E2 production by TiO2 nanoparticles in human gingival fibroblast. (2014) (19)
- Stimulation of Human Peripheral Blood Polymorphonuclear Cell Iodination by Lignin‐Related Substances (1991) (19)
- Recent Progress of Basic Studies of Natural Products and Their Dental Application (2018) (19)
- Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents (2017) (19)
- Interaction between sodium ascorbate and dopamine. (1998) (19)
- Decline of superoxide dismutase activity during antioxidant-induced apoptosis in HL-60 cells. (2002) (18)
- Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines. (2009) (18)
- Lucilianosides A and B, two novel tetranor-lanostane hexaglycosides from the bulbs of Chionodoxa luciliae (2002) (18)
- DNA microarray analysis of signaling pathway in macrophages stimulated by lignin-carbohydrate complex from lentinus edodes mycelia (LEM) extract. (2010) (18)
- Biological impact of contact with metals on cells. (2006) (18)
- Macrophage stimulation activity of antimicrobial N,N-dimethylaminoethyl paramylon. (1991) (18)
- Apoptosis-inducing activity and tumor-specificity of antitumor agents against oral squamous cell carcinoma (2010) (18)
- Synthesis and anticancer properties of mono Mannich bases containing vanillin moiety (2017) (18)
- Use of the monoclonal antibody M30 for detecting HSG cell apoptosis. (2000) (18)
- Anti-inflammatory Activity of Hangeshashinto in IL-1β-stimulated Gingival and Periodontal Ligament Fibroblasts. (2016) (18)
- New cardenolides from the seeds of Adonis aestivalis. (2012) (18)
- Changes in amino acid metabolism during activation of mouse macrophage-like cell lines. (2010) (18)
- Four New Steroidal Saponins from the Rhizomes of Helleborus orientalis (2005) (18)
- Cytotoxicity induced by docetaxel in human oral squamous cell carcinoma cell lines. (2013) (18)
- Enhancement of Dectin-2 gene expression by lignin-carbohydrate complex from Lentinus edodes mycelia extract (LEM) in a mouse macrophage-like cell line. (2011) (18)
- Cytotoxic 2-benzylidene-6-(nitrobenzylidene)cyclohexanones which display substantially greater toxicity for neoplasms than non-malignant cells. (2010) (17)
- Induction of DNA fragmentation by nicotine in human myelogenous leukemic cell lines. (1998) (17)
- Interaction between dental metals and antioxidants, assessed by cytotoxicity assay and ESR spectroscopy. (2002) (17)
- Chromatin structure and endonuclease sensitivity in human leukemic cell lines. (1996) (17)
- Ellagitannins of Davidia involucrata. I. Structure of Davicratinic Acid A and Effects of Davidia Tannins on Drug-Resistant Bacteria and Human Oral Squamous Cell Carcinomas (2017) (17)
- Oleanane and taraxerane glycosides from the roots of Gomphrena macrocephala. (2006) (17)
- Immunohistochemical detection of cytokeratin 18 and its neo-epitope in human salivary glands and pleomorphic adenomas. (2000) (17)
- Efficient utilization of licorice root by alkaline extraction. (2014) (17)
- Inhibition of NO production in LPS-stimulated mouse macrophage-like cells by trihaloacetylazulene derivatives. (2008) (17)
- Systemic effects of the occlusal destruction in guinea pigs. (1999) (17)
- Hypochlorite scavenging activity of polyphenols. (1995) (17)
- Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by azulenequinones. (2005) (17)
- Sequential cytotoxicity: a theory examined using a series of 3,5-bis(benzylidene)-1-diethylphosphono-4-oxopiperidines and related phosphonic acids. (2010) (17)
- Effects of prenylflavanones from Sophora species on growth and activation of mouse macrophage-like cell line. (2002) (17)
- Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines. (2005) (17)
- Inhibition by Moxa smoke of NO production and iNOS expression in mouse macrophage-like cells Raw 264.7. (2005) (17)
- POLYMERIC PHENYLPROPENOIDS ARE THE ACTIVE COMPONENTS IN THE PINE CONE EXTRACT THAT INHIBIT THE REPLICATION OF TYPE-1 HUMAN IMMUNODEFICIENCY VIRUS IN VITRO (1992) (17)
- Induction of DNA fragmentation in human myelogenous leukaemic cell lines by phenothiazine-related compounds. (1995) (17)
- Intracellular signalling cascades activated by the EGF receptor and/or by integrins, with potential relevance for branching morphogenesis of the fetal mouse submandibular gland. (2000) (17)
- Pilot clinical study of Sasa senanensis Rehder leaf extract treatment on lichenoid dysplasia. (2012) (17)
- Changes in intracellular concentrations of polyamines during apoptosis of HL-60 cells. (2003) (16)
- Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by Barbados cherry, a fruit of Malpighia emarginata DC. (2003) (16)
- Inhibition of epigallocatechin gallate-induced apoptosis by CoCl2 in human oral tumor cell lines. (1999) (16)
- Apoptosis-inducing activity of trihaloacetylazulenes against human oral tumor cell lines. (2006) (16)
- Nicorandil enhances the effect of endothelial nitric oxide under hypoxia–reoxygenation: Role of the KATPatp" were changed to "KATP". Please check.--> channel (2008) (16)
- Cytotoxicity of nocobactins NA-a, NA-b and their ferric complexes assessed by semiempirical molecular orbital method. (2005) (16)
- Protection of Differentiating Neuronal Cells from Amyloid β Peptide-induced Injury by Alkaline Extract of Leaves of Sasa senanensis Rehder. (2018) (16)
- Triterpene glycosides from the tubers of Anemone coronaria. (2009) (16)
- Quantitative Structure-Cytotoxicity Relationship of Oleoylamides. (2015) (16)
- Lanosterol and tetranorlanosterol glycosides from the bulbs of Muscari paradoxum. (2003) (16)
- Effect of cacao husk extract on human immunodeficiency virus infection (1991) (16)
- Cytotoxic activity of azulenequinones against human oral tumor cell lines. (2005) (16)
- Effect of two different groups of Chinese medicines on nitric oxide production by mouse macrophage-like cells. (2004) (16)
- Inhibition of NO production in LPS-stimulated mouse macrophage-like cells by benzo[b]cyclohept[e] [1,4]oxazine and 2-aminotropone derivatives. (2009) (16)
- Induction of apoptosis by dopamine in human oral tumor cell lines. (2000) (16)
- Tumor-specificity and type of cell death induced by phenoxazines. (2007) (16)
- Stimulation of Granulocytic Cell Iodination by Pine Cone Antitumor Substances (1989) (16)
- Structural requirements of hydroxylated coumarins for in vitro anti-Helicobacter pylori activity. (2003) (16)
- Quantitative structure-activity relationship (QSAR) analysis of tumor-specificity of 1,2,3,4-tetrahydroisoquinoline derivatives. (2011) (16)
- Quantitative Structure-Cytotoxicity Relationship of Aurones. (2017) (16)
- Two-Dimensional Electrophoretic Analysis of Nuclear Acidic Proteins in Senescent Human Diploid Cells (1979) (16)
- Quantitative structure-cytotoxicity relationship analysis of coumarin and its derivatives by semiempirical molecular orbital method. (2006) (16)
- Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells. (2009) (16)
- Metabolomic profiling of sodium fluoride-induced cytotoxicity in an oral squamous cell carcinoma cell line (2014) (15)
- Interaction between 2-Ethoxybenzoic Acid (EBA) and Eugenol, and Related Changes in Cytotoxicity (2003) (15)
- Search for New Type of Anticancer Drugs with High Tumor Specificity and Less Keratinocyte Toxicity. (2017) (15)
- Role of hydrogen peroxide for cell death induction by sodium 5,6-benzylidene-L-ascorbate. (1998) (15)
- Cytotoxicity and pro-inflammatory action of chemo-mechanical caries-removal agents against oral cells. (2014) (15)
- Steroidal glycosides from Furcraea foetida and their cytotoxic activity. (2009) (15)
- Functional Analysis of Natural Polyphenols and Saponins as Alternative Medicines (2012) (15)
- In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs (2019) (15)
- Lignified materials as medicinal resources. VI. Anti-HIV activity of dehydrogenation polymer of p-coumaric acid, a synthetic lignin, in a quasi-in-vivo assay system as an intermediary step to clinical trials. (1993) (15)
- Comparative analysis of cell death induction by cisplatin and 5-FU in human oral squamous and hepatocellular carcinoma cell lines. (2008) (15)
- Cytotoxicty and radical modulating activity of isoflavones and isoflavanones from Sophora species. (2004) (15)
- Declined asparagine synthetase mRNA expression and enhanced sensitivity to asparaginase in HL-60 cells committed to monocytic differentiation. (2009) (15)
- Effects of chemically defined tannins on poly (ADP-ribose) glycohydrolase activity. (1991) (15)
- Effect of antioxidants, oxidants, metals and saliva on cytotoxicity induction by sodium fluoride. (2003) (15)
- Stimulation of ascorbate-induced hypoxia by lignin. (1997) (15)
- Tumor-specific cytotoxicity and type of cell death induced by beta-cyclodextrin benzaldehyde inclusion compound. (2008) (15)
- Organ distribution and toxicity of lignin. (1999) (15)
- Effect of copper and iron ions on cytotoxicity induced by ascorbate, gallate and caffeate. (1997) (15)
- Effect of pine seed shell extract on microbial and viral infection. (1992) (14)
- Interaction between chlorogenic acid and antioxidants. (2000) (14)
- Enhancement of radical intensity and cytotoxic activity of ascorbate by PSK and lignins. (1996) (14)
- Aberration of chromosomes 8 and 11 in bladder cancer as detected by fluorescence in situ hybridization (2000) (14)
- Radical modulation activity of benzo[a]phenothiazine. (1997) (14)
- Quantitative Structure-Cytotoxicity Relationship of Newly Synthesized Piperic Acid Esters. (2017) (14)
- Quantitative Structure-Cytotoxicity Relationship of Chalcones. (2017) (14)
- 1-Aryl-2-dimethylaminomethyl-2-propen-1-one hydrochlorides and related adducts: A quest for selective cytotoxicity for malignant cells. (2008) (14)
- Renal cortical scarring in acute pyelonephritis. (1992) (14)
- Changes in intracellular concentrations of amino acids and polyamines during the apoptosis of HL-60 cells. (2000) (14)
- 3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins. (2016) (14)
- Stimulation of tumor necrosis factor-induced human myelogenous leukemic cell differentiation by high molecular weight PSK subfraction. (1989) (14)
- Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines. (2009) (14)
- Five New Triterpene Glycosides from Centella asiatica (2001) (14)
- Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates (2018) (14)
- Rapid determination of ascorbate by ESR spectroscopy. (1997) (14)
- Relationship between radical intensity and cytotoxic activity of dopamine-related compounds. (1998) (14)
- Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its bis- Mannich Derivatives (2015) (14)
- Induction of apoptosis by beta-diketones in human tumor cells. (2004) (14)
- Effect of pine seed shell extract on rotavirus and enterovirus infections (1991) (14)
- Stimulation by PSK of interleukin-1 production by human peripheral blood mononuclear cells. (1993) (14)
- Relationship between cytotoxic activity and dipole moment for phthalimido- and chloroethyl-phenothiazines. (1999) (14)
- Partial purification of novel differentiation-inducing substances(s) from hot water extract of Japanese pine cone. (1986) (14)
- Quantitative Structure-cytotoxicity Relationship of 3-Benzylidenechromanones. (2016) (14)
- Tumor-specific cytotoxicity and type of cell death induced by benzo[b]cyclohept[e][1,4]oxazine and 2-aminotropone derivatives. (2009) (14)
- Induction of cell death by combination treatment with cisplatin and 5-fluorouracil in a human oral squamous cell carcinoma cell line. (2007) (14)
- Chemical modification potentiates paramylon induction of antimicrobial activity. (1989) (14)
- Relationship between radical intensity and biological activity of cacao husk extracts. (1999) (14)
- Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines. (2008) (14)
- Induction of antiparasite activity by pine cone lignin-related substances. (1989) (13)
- Synergism of Alkaline Extract of the Leaves of Sasa senanensis Rehder and Antiviral Agents. (2016) (13)
- Analysis of type of cell death induced by topoisomerase inhibitor SN-38 in human oral squamous cell carcinoma cell lines. (2012) (13)
- Search of Neuroprotective Polyphenols Using the “Overlay” Isolation Method (2018) (13)
- Biological interaction between Sasa senanensis Rehder leaf extract and toothpaste ingredients. (2013) (13)
- Antiplasmid and carcinogenic molecular orbitals of benz[c]acridine and related compounds. (1993) (13)
- Calcium mobilization during nicotine-induced cell death in human glioma and glioblastoma cell lines. (1998) (13)
- Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines: relationship to electronic structure. (2009) (13)
- Effects of TiO2 nanoparticles on cytotoxic action of chemotherapeutic drugs against a human oral squamous cell carcinoma cell line. (2014) (13)
- Multiple immunological functions of extracts from the cone of Japanese white pine, Pinus parviflora Sieb. et Zucc. (1992) (13)
- Enhancement of Cytotoxicity of Three Apoptosis-inducing Agents Against Human Oral Squamous Cell Carcinoma Cell Line by Benzoxazinotropone. (2016) (13)
- Lignified materials as a potential medicinal resource. IV. Dehydrogenation polymers of some phenylpropenoids and their capacity to stimulate polymorphonuclear cell iodination. (1991) (13)
- Quantitative Structure–Cytotoxicity Relationship of Pyrano[4,3-b]chromones (2018) (13)
- COX-2 as possible target for the inhibition of PGE2 production by Rikko-san in activated macrophage. (2008) (13)
- Effect of glutathione-modulating compounds on platinum compounds-induced cytotoxicity in human glioma cell lines. (1999) (13)
- Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones (2019) (13)
- Interaction between antioxidants and hydroquinone/bisphenol. (1999) (13)
- Mitogenic activity of pine cone extracts against cultured splenocytes from normal and tumor-bearing animals. (1989) (12)
- Hormetic response of cultured normal and tumor cells to 2-aminotropone derivatives. (2010) (12)
- Prevention of Reactive Oxygen-Induced Endothelial Cell Injury by Blocking Its Process (1999) (12)
- Re-evaluation of Culture Condition of PC12 and SH-SY5Y Cells Based on Growth Rate and Amino Acid Consumption. (2017) (12)
- Spirostanol pentaglycosides from the underground parts of polianthestuberosa. (2002) (12)
- Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by benzocycloheptoxazines. (2008) (12)
- Radical Scavenging Activity and Inhibition of Macrophage NO Production by Fukinolic Acid, a Main Phenolic Constituent in Japanese Butterbur (Petasites japonicus) (2007) (12)
- Possible Role of Hydrogen Peroxide in Apoptosis Induction by Ascorbic Acid in Human Myelogenous Leukemic Cell Lines (1994) (12)
- Effect of the type of serum in the medium on sodium ascorbate-induced cytotoxicity. (1996) (12)
- Synthesis and Cytotoxicities of 2-[4-hydroxy-(3,5-bis-aminomethyl)- benzylidene]-indan-1-ones (2015) (12)
- Cytotoxic activity of selected trifluoromethyl ketones against oral tumor cells. (2006) (12)
- Cytotoxicity of dental compounds towards human oral squamous cell carcinoma and normal oral cells. (2013) (12)
- Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones (2016) (12)
- Induction of cell death by pro-oxidant action of Moxa smoke. (2002) (12)
- Anti-UV activity of Kampo medicines and constituent plant extracts: re-evaluation with skin keratinocyte system. (2014) (12)
- Inhibition of prostaglandin E2 production by flavone and its related compounds. (2010) (12)
- Tumor-specificity and type of cell death induced by vitamin K2 derivatives and prenylalcohols. (2008) (12)
- Immunomodulation activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines. (1993) (12)
- Effect of poly-herbal formula on NO production by LPS-stimulated mouse macrophage-like cells. (2002) (12)
- In Vitro Anti-tumor Activity of Azulene Amide Derivatives. (2018) (11)
- New biological activity of Rhinacanthus nasutus extracts. (2011) (11)
- Functionality of Anthocyanins as Alternative Medicine (2008) (11)
- Inhibition of NO production in LPS-stimulated mouse macrophage-like cells by trihaloacetylazulenes. (2006) (11)
- Quantitative structure-cytotoxicity relationship of newly synthesized tropolones determined by a semiempirical molecular-orbital method (PM5). (2010) (11)
- Nicorandil enhances the effect of endothelial nitric oxide under hypoxia-reoxygenation: role of the KATP channel. (2008) (11)
- Cytotoxicity of direct current with antibacterial agents against host cells in vitro. (2005) (11)
- Effect of DL-alpha-tocopherol (vitamin E) on the differentiation of mouse myeloid leukemia cell. (1981) (11)
- Tumor-specific cytotoxicity and type of cell death induced by sodium 5,6-benzylidene-L-ascorbate. (2008) (11)
- Anti-Halitosis Effect of Toothpaste Supplemented with Alkaline Extract of the Leaves of Sasa senanensis Rehder. (2016) (11)
- Tumour-specific cytotoxicity and structure-activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones. (2016) (11)
- Novel cytotoxic phenanthrenequinone from Odontioda Marie Noel 'Velano'. (2012) (11)
- Effect of tropolone, azulene and azulenequinone derivatives on prostaglandin E2 production by activated macrophage-like cells. (2009) (11)
- Distribution of TNF endogenously induced by various immunopotentiators and Lactobacillus casei in mice. (1992) (11)
- Cytotoxic and radical scavenging activity of blended herbal extracts. (2002) (11)
- Effect of cysteine, N-acetyl-L-cysteine and glutathione on cytotoxic activity of antioxidants. (1997) (11)
- Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives (2020) (11)
- Changes in amino acid pool and utilization during apoptosis in HL-60 cells induced by epigallocatechin gallate or gallic acid. (2001) (11)
- Quantitative structure-cytotoxicity relationship of piperic acid amides. (2014) (11)
- Quantitative structure-cytotoxicity relationship analysis of phenoxazine derivatives by semiempirical molecular-orbital method. (2007) (11)
- Convallasaponin A, a new 5beta-spirostanol triglycoside from the rhizomes of Convallaria majalis. (2007) (11)
- Quantitative Structure–Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives (2018) (11)
- Aestivalosides A-L, twelve pregnane glycosides from the seeds of Adonis aestivalis. (2018) (11)
- Anti-inflammatory potential of Rikkosan based on IL-1β network through macrophages to oral tissue cells. (2014) (11)
- Protection of Bortezomib-induced Neurotoxicity by Antioxidants (2020) (11)
- Lignified materials as potential medicinal resources. III. Diversity of biological activity and possible molecular species involved. (1990) (11)
- Relationship between cytotoxic activity and radical intensity of isoflavones from Sophora species. (2001) (11)
- Effect of cobalt ion on radical intensity and cytotoxic activity of antioxidants. (2000) (11)
- New biological activities of Rhinacanthins from the root of Rhinacanthus nasutus. (2013) (11)
- Synthesis and Cytotoxicities of New Azafluorenones with Apoptotic Mechanism of Action and Cell Cycle Analysis. (2019) (11)
- A comparative in vitro efficacy of conventional rotatory and chemomechanical caries removal: Influence on cariogenic flora, microhardness, and residual composition (2014) (10)
- Single instillation of hydroxypropylcellulose-doxorubicin as treatment for superficial bladder carcinoma (2004) (10)
- Biological activity of SE-10, granulated powder of Sasa senanensis Rehder leaf extract. (2012) (10)
- Effect of contact with titanium alloys on the proliferation of mouse osteoblastic cells in culture. (2010) (10)
- Structural characterization of anti-UV components from Sasa senanensis Rehder extract. (2013) (10)
- Anatomical and electrophysiological mechanisms for asymmetrical excitatory propagation in the rat insular cortex: In vivo optical imaging and whole‐cell patch‐clamp studies (2013) (10)
- Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides. (2021) (10)
- Tumor-specificity and radical scavenging activity of poly-herbal formula. (2002) (10)
- Methionine oxidation and apoptosis induction by ascorbate, gallate and hydrogen peroxide. (1997) (10)
- Relationship between pi-electron distribution and anticancer activity of benzo[a]phenothiazines. (1992) (10)
- Cytotoxic activity of polyprenylalcohols and vitamin K2 derivatives. (2000) (10)
- Effects of isoflavones from Sophora species on the growth and activation of a mouse macrophage-like cell line. (2002) (10)
- Cytotoxicity and type of cell death induced by midazolam in human oral normal and tumor cells. (2012) (10)
- Radical intensity and cytotoxicity of butylated hydroxyanisole and its orthobisphenol dimer. (1999) (10)
- Quantitative Structure–Cytotoxicity Relationship of 2-Styrylchromones (2019) (10)
- Anti-UV activity of newly-synthesized water-soluble azulenes. (2013) (10)
- Sodium 5,6‐benzylidene‐L‐ascorbate induces oxidative stress, autophagy, and growth arrest in human colon cancer HT‐29 cells (2010) (10)
- New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6‐(3‐Halogenated phenyl‐2‐propen‐1‐oyl)‐2(3H)‐benzoxazolones (2020) (10)
- A rare type of sesquiterpene and β-santalol derivatives from Santalum album and their cytotoxic activities. (2014) (10)
- Biological Activity of Cacao Husk and Mass Lignin-Carbohydrate Complexes (2013) (10)
- Production of hydrogen peroxide in cancerous tissue by intravenous administration of sodium 5,6-benzylidene-L-ascorbate. (1999) (9)
- Quantitative Structure–Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives (2018) (9)
- Non-apoptotic cell death induced by nutritional starvation in J774.1 mouse macrophage-like cell line. (2009) (9)
- Photodynamic Therapy with Pyoktanin Blue and Diode Laser for Elimination of Enterococcus faecalis (2018) (9)
- Enhancement of sodium fluoride-induced cell death by centrifugal force. (2006) (9)
- Kampo Therapies and the Use of Herbal Medicines in the Dentistry in Japan (2019) (9)
- Quantitative structure-cytotoxicity relationship of phenylpropanoid amides. (2014) (9)
- Pine Cone Antitumor Substances Stimulate Cytotoxic Factor Production in Young Mice, but not in Aged or Tumor-Bearing Mice (1989) (9)
- Inhibition of cytotoxic activity of ascorbate by human cancer patient sera. (1997) (9)
- Induction of apoptotic cell death by direct-current treatment in human leukemic cell lines (2005) (9)
- Effect of antitumor agents on cytotoxicity induction by sodium fluoride. (2003) (9)
- Protection by antioxidants of copper-induced decline of proliferation and SOD activity. (2005) (9)
- Effect of alpha-tocopherol on cytotoxicity induced by UV irradiation and antioxidants. (1997) (9)
- Serum calcium-decreasing factor, caldecrin, ameliorates muscular dystrophy in dy/dy mice. (2011) (9)
- Chemical structure and tumor type specificity of "half-mustard type" phenothiazines. (1999) (9)
- Comparative study of the antitumor action between sodium 5,6-benzylidene-L-ascorbate and sodium ascorbate (minireview). (1997) (9)
- Quantitative Structure-Cytotoxicity Relationship of 2-Azolylchromones. (2018) (9)
- Effect of antioxidants on radical intensity and cytotoxicity of hydroquinone. (2000) (9)
- Quantitative Structure–Cytotoxicity Relationship of Furo[2,3-b]chromones (2018) (9)
- Enhancement of radical intensity and cytotoxic activity of ascorbate by hyperthermia. (1996) (9)
- Treatment of Herpes Simplex Virus with Lignin-Carbohydrate Complex Tablet, an Alternative Therapeutic Formula (2012) (9)
- Inhibition of human immunodeficiency virus forward and reverse transcription by PC6, a natural product from cones of pine trees. (1991) (9)
- Tumor-specific cytotoxic activity of polyphenols, terpenoids, ketones and other synthetic compounds. (2005) (9)
- Effect of endodontic agents on cytotoxicity induction by sodium fluoride. (2003) (9)
- Concentration-dependent effect of Rikko-san on the prostaglandin E2 production by mouse macrophage-like cells. (2006) (9)
- Radical production and cytotoxic activity of tert-butyl-substituted phenols. (2001) (9)
- Effect of sodium benzylideneascorbate on chemically-induced tumors in rats. (1993) (9)
- Quantitative structure-cytotoxicity relationship of newly synthesised trihaloacetylazulenes determined by a semi-empirical molecular-orbital method (PM5). (2011) (9)
- Steroidal Glycosides from Convallaria majalis Whole Plants and Their Cytotoxic Activity (2017) (9)
- Further Quantitative Structure–Cytotoxicity Relationship Analysis of 3-Styrylchromones (2019) (9)
- Inhibition by Rikko-san and its major ingredients of LPS-stimulated nitric oxide production by mouse macrophage-like cells. (2005) (9)
- Changes in Metabolic Profiles of Human Oral Cells by Benzylidene Ascorbates and Eugenol (2018) (9)
- Development of Newly Synthesized Chromone Derivatives with High Tumor Specificity against Human Oral Squamous Cell Carcinoma (2020) (9)
- Stimulation of human peripheral blood polymorphonuclear cell iodination by PSK subfractions. (1990) (8)
- In Vitro Antitumor Activity of Alkylaminoguaiazulenes. (2018) (8)
- Enhancement of radical intensity and cytotoxic activity of ascorbate by Crataegus cuneata Sieb et. Zucc. extracts. (1998) (8)
- Thyroid hormone (3,5,3'-triido-L-thyronine) masking/inversion of stimulatory effect of androgen on expression of mk1, a true tissue kallikrein, in the mouse submandibular gland. (1999) (8)
- Interaction between hydroquinone and ascorbic acid derivatives: quenching effect of organic solvents. (2000) (8)
- Adhesion and Proliferation of Osteoblastic Cells on Hydroxyapatite-dispersed Ti-based Composite Plate (2019) (8)
- Furostanol glycosides from the rhizomes of Helleborus orientalis (2010) (8)
- QSAR of molecular structure and cytotoxic activity of vitamin K2 derivatives with concept of absolute hardness. (2007) (8)
- 27-norlanostane glycosides from the bulbs of Muscari paradoxum. (2004) (8)
- Quantification of enhanced osteoblastic adhesion to ultraviolet-treated titanium plate. (2010) (8)
- EBV LMP1 in Gingival Epithelium Potentially Contributes to Human Chronic Periodontitis via Inducible IL8 Production (2019) (8)
- Chelating effect of human serum proteins on metal-catalyzed ascorbate radical generation. (1997) (8)
- Effect of Sairei-to and its ingredients on prostaglandin E2 production by mouse macrophage-like cells. (2008) (8)
- Metabolomic profiling of tumor-infiltrating macrophages during tumor growth (2020) (8)
- Polyhydroxylated spirostanol saponins from the tubers of Dioscorea polygonoides. (2005) (8)
- QSAR Prediction Model to Search for Compounds with Selective Cytotoxicity Against Oral Cell Cancer (2019) (8)
- Stimulation of arginine consumption and asparagine production in LPS-activated macrophages. (2002) (8)
- Dental Application of Natural Products (2018) (8)
- Endonuclease activity and hydrogen peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines. (1999) (8)
- Hydrolyzable Tannins of Tamaricaceous Plants. 7.1 Structures and Cytotoxic Properties of Oligomeric Ellagitannins from Leaves of Tamarix nilotica and Cultured Tissues of Tamarix tetrandra. (2016) (8)
- Disruption of amino acid metabolism in human myelogenous leukemic cell lines destined to die after contact with metal plates. (2007) (8)
- Amurensiosides L-P, Five New Cardenolide Glycosides from the Roots of Adonis amurensis (2015) (8)
- Partial Protection of Paclitaxel-induced Neurotoxicity by Antioxidants (2018) (7)
- Induction of anti-Escherichia coli activity in mice by phenothiazines, benzo[a]phenothiazines and benz[c]acridines. (1992) (7)
- Enhancement of cytotoxic activity of ascorbate by Acer nikoense Maxim. Extracts. (1997) (7)
- Relationship between electronic structure and cytotoxic activity of azulenes. (2006) (7)
- Induction of non-apoptotic cell death by sodium 5,6-benzylidene-L-ascorbate in a human salivary gland tumor cell line. (1999) (7)
- Relationship between biological activity and dipole moment in benzo[a]phenothiazines. (1997) (7)
- Relationship between differentiation-inducing activity and hypercalcemic activity of hexafluorotrihydroxyvitamin D3 derivatives. (2004) (7)
- Studies on the retention of the mucous-membrane-adhesive anticancer agent hydroxypropylcellulose doxorubicin. (1992) (7)
- Re-evaluation of antitumor activity of Cepharanthin. (2002) (7)
- Stability of sodium 5,6-benzylidene-L-ascorbate. (1995) (7)
- Morphological features of osteoblasts cultured on ultraviolet-irradiated titanium plates. (2011) (7)
- Estimation of relationship between the structure of 1,2,3,4-tetrahydroisoquinoline derivatives determined by a semiempirical molecular-orbital method and their cytotoxicity. (2009) (7)
- Effect of saliva, epigallocatechin gallate and hypoxia on Cu-induced oxidation and cytotoxicity. (2007) (7)
- Norlanostane and lanostane glycosides from the bulbs of Chionodoxa luciliae and their cytotoxic activity. (2003) (7)
- 1,3‐Diaryl‐2‐propenones and 2‐Benzylidene‐1,3‐indandiones: A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells (2010) (7)
- Interaction of pine cone extract fraction VI with mutagens. (1993) (7)
- Advantages of second line estramustine for overall survival of hormone-refractory prostate cancer (HRPC) patients. (2009) (7)
- Glutathione can efficiently prevent direct current-induced cytotoxicity. (2008) (7)
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- Serum calcium-decreasing factor, caldecrin, protects against amyloid-β peptide toxicity by proteolytic cleavage of the peptide (2009) (0)
- Effect of titanium dioxide nanoparticle on proliferation, drug-sensitivity, inflammation, and metabolomic profiling of human oral cells (2016) (0)
- Effect of Low-intensity Pulsed Ultrasound on Healing of Bone Defects in Rat Tibia as Measured by Reconstructed Three-dimensional Analysis of Micro CT Images (2022) (0)
- Prevention of age-related diseases by lutein and zeaxanthin. (2006) (0)
- Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity (2022) (0)
- Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with aztreonam. (1986) (0)
- Effect of Curdlan, A Bacterial Water-Insoluble β-1, 3-Glucan, on Experimental Escherichia coli Infection in Mice (1991) (0)
- Enamel Matrix Derivative in Diffusion Chamber Implanted Subcutaneously in Rat Induces Formation of Fibrous Connective Tissue Containing Abundant Blood Vessels (2021) (0)
- Intravesical instillation of hydroxypropylcelluloseadriamycin and combined treatment with hyperthermia for bladder cancer (1990) (0)
- [Our experience with combined intravesical instillation therapy of superficial bladder tumor using Aclacinomycin-A (ACM) and cytosine arabinoside (CA)]. (1987) (0)
- Change in Amino Acid Pools During Neuronal Differentiation of PC12 Cells (2018) (0)
- Contact ND-YAG Laser Irradiation for Bladder Cancer (1987) (0)
- 学会ポスター発表 Component analysis and antioxidant activity of Mulberry juice (2008) (0)
- 1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)-4-Piperidone hydrochloride and Related Compounds: Potent Cytotoxins Demonstrating Greater Toxicity to Neoplasms Than Non-Malignant Cells. (2022) (0)
- Molecular Requirements of Lignin—Carbohydrate Complexes for Expression of Unique Biological Activities. (2006) (0)
- Thyroid hormone inversion of stimulatory effect of androgen on induction of mk1, a true tissue kallikrein, in the mouse submandibular gland (1999) (0)
- Treatment of the Urinary Bladder Carcinoma in Situ by Simultaneous Intra-Vesical Instillation of Hydroxypropylcellulose-Doxorubicin and Verapamil (1992) (0)
- P-48 Tannins of Tamarix Plants: Structures of New Ellagitannins, Cytotoxicity of Tamarix Tannins, and Accumulation of Tannins in Cultured Shoots (2010) (0)
- Contents, Vol. 114, Supplment 1, 1997 (1997) (0)
- Constituents of the Leaves of Odontioda Marie Noel 'Velano' with Inhibitory Activity on RANKL-induced Osteoclast Differentiation (2015) (0)
- [Silicone pig-tail catheter for the upper urinary tract]. (1986) (0)
- Pathological Studies Of The Bladder Wall After Contact Nd-YAG Laser Irradiation In Treatment For Bladder Cancer. (1988) (0)
- Effect of Neoadjuvant Hormonal Therapy of Surgical Margin Status in Patients with Prostate Cancer Treated by Radical Prostatectomy (2007) (0)
- Activation of the ERK-1/2 signaling cascade in EGF-stimulated branching morphogenesis of fetal mouse submandibular glands (1998) (0)
- [The value of computed tomography in acute pyelonephritis]. (1988) (0)
- Synthesis and Cytotoxic Activity of (4-Substituted-benzylidene)-(3-Phenyl-1,2,4-Oxadiazol-5-YL)Methylamines (2016) (0)
- Abstract. We established the optimal conditions for the induction of cell death by cisplatin (CDDP) and 5-fluorouracil (5-FU) in human oral squamous cell carcinoma (HSC-2, HSC-3, HSC-4) and human hepatocellular carcinoma (2008) (0)
- Therapeutic Effects of 8 MHz-radiofrequency-Induced Hyperthermia on Prostatic Hypertrophy (1993) (0)
- Establishment and Characterization of a Human Glioblastoma Cell Line Which Expresses Somatostatin and its Functional Receptor (1999) (0)
- Measurement of oral malodor with Halimeter under various conditions (2001) (0)
- Hormonal regulation of mK1, a true tissue kallikrein in mouse submandibular gland (2000) (0)
- New Cardenolides from the Seeds of Adonis aestivalis (2013) (0)
- Pharmacokinetic and clinical studies on carumonam (1987) (0)
- m1) Cell differentiation. (1982) (0)
- A Rare Type of Sesquiterpene and β‐Santalol Derivatives from Santalum album and Their Cytotoxic Activities. (2015) (0)
- New anti-Oxidative Compounds from Rhinacanthus nasutus. (2015) (0)
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What Schools Are Affiliated With Hiroshi Sakagami?
Hiroshi Sakagami is affiliated with the following schools:
