Hiroshi Sugiyama
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Hiroshi Sugiyamachemistry Degrees
Chemistry
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Organic Chemistry
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Chemistry
Hiroshi Sugiyama's Degrees
- PhD Chemistry University of Tokyo
- Masters Chemistry University of Tokyo
- Bachelors Chemistry University of Tokyo
Why Is Hiroshi Sugiyama Influential?
(Suggest an Edit or Addition)Hiroshi Sugiyama's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Theoretical Studies of GG-Specific Photocleavage of DNA via Electron Transfer: Significant Lowering of Ionization Potential and 5‘-Localization of HOMO of Stacked GG Bases in B-Form DNA (1996) (494)
- The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution. (2006) (338)
- Photoinduced DNA Cleavage via Electron Transfer: Demonstration That Guanine Residues Located 5' to Guanine Are the Most Electron-Donating Sites (1995) (333)
- A DNA-based molecular motor that can navigate a network of tracks. (2012) (314)
- Direct observation of stepwise movement of a synthetic molecular transporter. (2011) (297)
- Mapping of the Hot Spots for DNA Damage by One-Electron Oxidation: Efficacy of GG Doublets and GGG Triplets as a Trap in Long-Range Hole Migration (1998) (266)
- Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease (2019) (256)
- Clinicopathological features of adult-onset neuronal intranuclear inclusion disease (2016) (216)
- A light-driven three-dimensional plasmonic nanosystem that translates molecular motion into reversible chiroptical function (2016) (212)
- Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb) (2006) (191)
- Visualization of dynamic conformational switching of the G-quadruplex in a DNA nanostructure. (2010) (187)
- Regulation of DNA methylation using different tensions of double strands constructed in a defined DNA nanostructure. (2010) (186)
- The C-Kit Receptor-Mediated Signal Transduction and Tumor-Related Diseases (2013) (186)
- A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. (2011) (185)
- Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy (2019) (183)
- Single-molecule analysis using DNA origami. (2012) (175)
- Programmed two-dimensional self-assembly of multiple DNA origami jigsaw pieces. (2011) (173)
- Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides. (2006) (173)
- (P)-helicene displays chiral selection in binding to Z-DNA. (2004) (172)
- RNA-DNA Triplex Formation by Long Noncoding RNAs. (2016) (162)
- A chiral wedge molecule inhibits telomerase activity. (2010) (157)
- Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly. (2011) (155)
- Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures. (2010) (148)
- Chemical Approaches to DNA Nanotechnology (2009) (148)
- Copper-dependent cleavage of DNA by bleomycin. (1987) (147)
- Lipid-bilayer-assisted two-dimensional self-assembly of DNA origami nanostructures (2015) (147)
- Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory CpG motifs to immune cells. (2012) (142)
- Photo-controllable DNA origami nanostructures assembling into predesigned multiorientational patterns. (2012) (139)
- Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone. (2001) (137)
- Product Analysis of GG-Specific Photooxidation of DNA via Electron Transfer: 2-Aminoimidazolone as a Major Guanine Oxidation Product (1998) (136)
- 13 C nuclear magnetic resonance spectra of glucobioses, glucotrioses, and glucans (1973) (134)
- DNA prism structures constructed by folding of multiple rectangular arms. (2009) (120)
- State transitions by molecules. (1999) (115)
- Zinc-finger proteins for site-specific protein positioning on DNA-origami structures. (2012) (115)
- A versatile DNA nanochip for direct analysis of DNA base-excision repair. (2010) (112)
- Highly sequence-selective photoreaction of 5-bromouracil-containing deoxyhexanucleotides (1990) (111)
- SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions (2017) (106)
- Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates. (2014) (103)
- Ligand Design to Acquire Specificity to Intended G-Quadruplex Structures. (2018) (103)
- DNA-based hybrid catalysts for asymmetric organic synthesis. (2010) (102)
- Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface. (2014) (101)
- Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseases. (2006) (95)
- Single-molecule imaging of dynamic motions of biomolecules in DNA origami nanostructures using high-speed atomic force microscopy. (2014) (95)
- Intramolecular folding in three tandem guanine repeats of human telomeric DNA. (2012) (94)
- Programmed-assembly system using DNA jigsaw pieces. (2010) (91)
- Impact of glucocerebrosidase mutations on motor and nonmotor complications in Parkinson's disease (2015) (89)
- Structure of a human telomeric DNA sequence stabilized by 8‐bromoguanosine substitutions, as determined by NMR in a K+ solution (2007) (84)
- Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure. (2015) (84)
- Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole–imidazole polyamide conjugate (2015) (81)
- Genetic regulation of the RUNX transcription factor family has antitumor effects (2017) (80)
- Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter. (2011) (77)
- Neuropathological studies on strains of senescence-accelerated mice (SAM) with age-related deficits in learning and memory (1997) (77)
- A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts (2012) (77)
- Delirium and High Fever Are Associated with Subacute Motor Deterioration in Parkinson Disease: A Nested Case-Control Study (2014) (75)
- Single-molecule mechanochemical sensing using DNA origami nanostructures. (2014) (74)
- UVR-induced G-C to C-G transversions from oxidative DNA damage. (2005) (73)
- Synthesis, structure and thermodynamic properties of 8-methylguanine-containing oligonucleotides: Z-DNA under physiological salt conditions. (1996) (73)
- Photoinduced deoxyribose C2' oxidation in DNA. Alkali-dependent cleavage of erythrose-containing sites via a retroaldol reaction (1993) (72)
- Two-dimensional DNA origami assemblies using a four-way connector. (2011) (71)
- DNA origami technology for biomaterials applications. (2013) (70)
- Chemistry of thermal degradation of abasic sites in DNA. Mechanistic investigation on thermal DNA strand cleavage of alkylated DNA. (1994) (69)
- Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide. (2004) (69)
- Design of a G-quadruplex topology through glycosidic bond angles. (2009) (69)
- Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations. (2012) (68)
- 8-Methylguanosine: a powerful Z-DNA stabilizer. (2003) (68)
- State-of-the-art high-speed atomic force microscopy for investigation of single-molecular dynamics of proteins. (2014) (67)
- Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure. (2012) (66)
- Engineering RNA-protein complexes with different shapes for imaging and therapeutic applications. (2014) (65)
- A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA. (2016) (64)
- Progress and Prospects of Pyrrole‐Imidazole Polyamide–Fluorophore Conjugates as Sequence‐Selective DNA Probes (2012) (63)
- Helical structure and circular dichroism spectra of DNA: a theoretical study. (2013) (63)
- A nanothermometer based on the different pi stackings of B- and Z-DNA. (2003) (62)
- Photochemical hydrogen-deuterium exchange reaction of tryptophan: the role in nonradiative decay of singlet tryptophan (1984) (62)
- A pyrrole-imidazole polyamide targeting transforming growth factor-beta1 inhibits restenosis and preserves endothelialization in the injured artery. (2009) (61)
- Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content. (2010) (61)
- Inhibition of MMP‐9 transcription and suppression of tumor metastasis by pyrrole‐imidazole polyamide (2010) (61)
- DNA origami based visualization system for studying site-specific recombination events. (2014) (59)
- Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts (2014) (59)
- Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences. (2013) (59)
- Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA. (1997) (59)
- Direct and real-time observation of rotary movement of a DNA nanomechanical device. (2013) (59)
- Analysis of products formed during bleomycin-mediated DNA degradation. (1985) (59)
- Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG). (1988) (59)
- Synthetic Pyrrole-Imidazole Polyamide Inhibits Expression of the Human Transforming Growth Factor-β1 Gene (2005) (59)
- Photoresponsive DNA nanocapsule having an open/close system for capture and release of nanomaterials. (2014) (58)
- Bis(hydroperoxy)naphthaldiimide as a “Photo‐Fenton Reagent”: Sequence‐Specific Photocleavage of DNA (1991) (57)
- Covalent alkylation of DNA with duocarmycin A. Identification of abasic site structure. (1990) (57)
- Biomolecule-based switching devices that respond inversely to thermal stimuli. (2005) (56)
- NanoScript: A Nanoparticle-Based Artificial Transcription Factor for Effective Gene Regulation (2014) (56)
- DNA Origami Nanomachines (2018) (56)
- Confined space facilitates G-quadruplex formation. (2017) (54)
- Synthesis and properties of PI polyamide-SAHA conjugate (2009) (54)
- Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells. (2015) (53)
- Synthetic Small Molecules for Epigenetic Activation of Pluripotency Genes in Mouse Embryonic Fibroblasts (2011) (53)
- Water revealed as molecular mirror when measuring low concentrations of sugar with near infrared light. (2015) (52)
- Nature-Inspired Design of Smart Biomaterials Using the Chemical Biology of Nucleic Acids (2016) (52)
- Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome (2018) (52)
- Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame (2013) (50)
- New synthetic method of 5-formyluracil-containing oligonucleotides and their melting behavior (1996) (50)
- Anticancer activities of alkylating pyrrole–imidazole polyamides with specific sequence recognition (2010) (50)
- DNA strand scission by bleomycin: catalytic cleavage and strand selectivity (1986) (49)
- Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation. (2002) (48)
- Structure of the alkali-labile product formed during iron(II)-bleomycin-mediated DNA strand scission (1985) (47)
- Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy. (1998) (47)
- Development of a new method for synthesis of tandem hairpin pyrrole-imidazole polyamide probes targeting human telomeres. (2013) (47)
- Development of DNA-Based Hybrid Catalysts through Direct Ligand Incorporation: Toward Understanding of DNA-Based Asymmetric Catalysis (2014) (47)
- Corrigendum: Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (2015) (47)
- Pyrrole-imidazole hairpin polyamides with high affinity at 5′–CGCG–3′ DNA sequence; influence of cytosine methylation on binding (2008) (47)
- Remarkably Stable Parallel-Stranded Oligonucleotides Containing 5-Methylisocytosine and Isoguanine (1996) (46)
- Guided assembly of tetramolecular G-quadruplexes. (2013) (46)
- Preparation of chemically modified RNA origami nanostructures. (2014) (45)
- Substrate recognition by Escherichia coli MutY using substrate analogs. (1999) (45)
- Evidence for intrastrand C2′ hydrogen abstraction in photoirradiation of 5-halouracil-containing oligonucleotides by using stereospecifically C2′-deuterated deoxyadenosine (1996) (45)
- Distamycin A modulates the sequence specificity of DNA alkylation by duocarmycin A. (1996) (45)
- Periodic acid-Schiff (PAS)-positive, granular structures increase in the brain of senescence accelerated mouse (SAM) (2004) (45)
- Photoreaction at 5'-(G/C)AA(Br)UT-3' sequence in duplex DNA: efficient generation of uracil-5-yl radical by charge transfer. (2007) (45)
- Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts. (2014) (44)
- Efficient generation of 2'-deoxyuridin-5-yl at 5'-(G/C)AA(X)U(X)U-3' (X = Br, I) sequences in duplex DNA under UV irradiation. (2005) (44)
- Hydrochlorothiazide Enhances UVA‐Induced DNA Damage (2013) (44)
- Mechanism of DNA Strand Scission Induced by (1,10-Phenanthroline)copper Complex: Major Direct DNA Cleavage Is Not through 1‘,2‘-Dehydronucleotide Intermediate nor β-Elimination of Forming Ribonolactone (2000) (43)
- Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics (2015) (43)
- A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell. (2013) (43)
- Single-Molecule Observation of the Photoregulated Conformational Dynamics of DNA Origami Nanoscissors. (2017) (43)
- Baseline C-Reactive Protein Levels and Life Prognosis in Parkinson Disease (2015) (43)
- Identification of Repair Enzymes for 5-Formyluracil in DNA (2000) (42)
- Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure. (2015) (42)
- DNA alkylation by pyrrole-imidazole seco-CBI conjugates with an indole linker: sequence-specific DNA alkylation with 10-base-pair recognition through heterodimer formation. (2007) (42)
- Electroreductive hydrocoupling of activated olefins with ketones or aldehydes in the presence of trimethylchlorosilane (1980) (42)
- Highly efficient DNA interstrand crosslinking induced by an antitumor antibiotic, carzinophilin (1999) (42)
- DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells. (2005) (42)
- Imidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairs. (1999) (41)
- N 1-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells (2020) (41)
- HIV-1 nucleocapsid proteins as molecular chaperones for tetramolecular antiparallel G-quadruplex formation. (2013) (41)
- Rational Design of Sequence-Specific DNA Alkylating Agents Based on Duocarmycin A and Pyrrole−Imidazole Hairpin Polyamides (1999) (40)
- Synthesis of 6-(2-thienyl)purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides. (2001) (40)
- Stable lariat formation based on a G-quadruplex scaffold. (2008) (40)
- Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. (2014) (40)
- Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells. (2016) (39)
- RNA-templated DNA origami structures. (2013) (39)
- An efficient, site-specific DNA target for bleomycin (1985) (39)
- Inhibition of transcription at a coding sequence by alkylating polyamide. (2003) (39)
- Sequence-specific DNA binding Pyrrole-imidazole polyamides and their applications. (2018) (39)
- G-quadruplex structures of human telomere DNA examined by single molecule FRET and BrG-substitution. (2008) (39)
- Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides. (2004) (39)
- Two subtypes of Churg–Strauss syndrome with neuropathy: the roles of eosinophils and ANCA (2011) (39)
- Highly emissive deoxyguanosine analogue capable of direct visualization of B-Z transition. (2014) (39)
- DNA strand scission by bleomycin group antibiotics. (1985) (39)
- DNA as a Chiral Scaffold for Asymmetric Synthesi (2012) (38)
- First International Meeting on Quadruplex DNA. (2007) (38)
- A novel guanine N3 alkylation by antitumor antibiotic duocarmycin A. (1993) (38)
- Purification and characterization of Caenorhabditis elegans NTH, a homolog of human endonuclease III: essential role of N-terminal region. (2009) (38)
- Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes. (2012) (38)
- Stereospecific 1,2-Hydride Shift in Ribonolactone Formation in the Photoreaction of 2'-Iododeoxyuridine (1995) (38)
- Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet. (2004) (38)
- Excited-state behavior of tryptamine and related indoles. Remarkably efficient intramolecular proton-induced quenching (1988) (37)
- Efficient DNA alkylation by a pyrrole-imidazole CBI conjugate with an indole linker: sequence-specific alkylation with nine-base-pair recognition. (2006) (37)
- Direct visualization of the movement of a single T7 RNA polymerase and transcription on a DNA nanostructure. (2012) (37)
- Specific detection of C-4' hydroxylated abasic sites generated by bleomycin and neocarzinostatin in DNA (1990) (37)
- Baseline Plasma C-Reactive Protein Concentrations and Motor Prognosis in Parkinson Disease (2015) (36)
- Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta. (2007) (36)
- Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach. (2013) (36)
- Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures (2018) (35)
- A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network. (2015) (35)
- Programmable genetic switches to control transcriptional machinery of pluripotency (2012) (35)
- Development of DNA Metalloenzymes Using a Rational Design Approach and Application in the Asymmetric Diels-Alder Reaction (2015) (35)
- Concerted DNA recognition and novel site-specific alkylation by duocarmycin A with distamycin A. (1993) (34)
- Environment‐Dependent Self‐Assembly of DNA Origami Lattices on Phase‐Separated Lipid Membranes (2018) (34)
- Photochemical approach to probing different DNA structures. (2006) (34)
- Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates. (2012) (34)
- Overview of Formation of G‐Quadruplex Structures (2010) (34)
- Sequence specificity, reactivity, and antitumor activity of DNA-alkylating pyrrole-imidazole diamides. (2003) (34)
- Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein. (2002) (34)
- Discrimination of Hairpin Polyamides with an α-Substituted-γ-aminobutyric Acid as a 5‘-TG-3‘ Reader in DNA Minor Groove (2006) (34)
- Antitumor activity of sequence‐specific alkylating agents: Pyrolle‐imidazole CBI conjugates with indole linker (2006) (34)
- Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity. (2013) (33)
- A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm (2017) (33)
- Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide. (2014) (33)
- Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame. (2014) (33)
- Translation-dependent unwinding of stem–loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs (2019) (33)
- Targeting 24 bp within Telomere Repeat Sequences with Tandem Tetramer Pyrrole-Imidazole Polyamide Probes. (2016) (33)
- Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold. (2012) (32)
- Photochemical determination of different DNA structures (2007) (32)
- A novel ribose C-4' hydroxylation pathway in neocarzinostatin-mediated degradation of oligonucleotides (1989) (32)
- A novel gene silencer, pyrrole–imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function (2009) (32)
- Rearrangement of α to β-Aspartyl Peptide with Anhydrous Hydrogen Fluoride (1973) (32)
- Conformation-Dependent Photochemistry of 5-Halouracil-Containing DNA: Stereospecific 2‘α-Hydroxylation of Deoxyribose in Z-form DNA (1999) (32)
- Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Attenuates Restenosis of the Artery After Injury (2008) (31)
- Photoinduced DNA strand scission by cobalt bleomycin green complex (1989) (31)
- Photoreaction of thymidine with alkylamines. Application to selective removal of thymine from DNA (1983) (31)
- Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate (2017) (30)
- Immunotherapies: The Blockade of Inhibitory Signals (2012) (30)
- Single-Molecule Visualization of the Activity of a Zn(2+)-Dependent DNAzyme. (2015) (30)
- Holliday junction resolvases mediate chloroplast nucleoid segregation (2017) (30)
- Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove. (2011) (30)
- Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores (2016) (30)
- Advancing Small‐Molecule‐Based Chemical Biology with Next‐Generation Sequencing Technologies (2015) (30)
- Interactions of deglycosylated cobalt(III)-pepleomycin (green form) with DNA based on NMR structural studies,. (1997) (30)
- 6α-Hydroxyeurycomalactone, a quassinoid from Eurycoma longifolia (1992) (29)
- Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure (2014) (29)
- Peroneal nerve palsy following acupuncture treatment. A case report. (2003) (29)
- A novel cyclization pathway in activation of neocarzinostatin chromophore by thiol under physiological conditions (1992) (29)
- Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold. (2011) (29)
- A study of the conformation of β-1,4-linked glucose oligomers, cellobiose to cellohexaose, in solution (2000) (29)
- Mimicking membrane-related biological events by DNA origami nanotechnology. (2015) (28)
- Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions. (2015) (28)
- Subclinical Elevation of Plasma C-Reactive Protein and Illusions/Hallucinations in Subjects with Parkinson’s Disease: Case–control Study (2014) (28)
- CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome (2021) (28)
- RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells (2018) (28)
- Sequence-specific alkylation of double-strand human telomere repeat sequence by pyrrole-imidazole polyamides with indole linkers. (2006) (28)
- Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model (2015) (28)
- Clinical grade iPS cells: need for versatile small molecules and optimal cell sources. (2013) (28)
- Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates. (2014) (27)
- Photochemical ring opening of thymidine and thymine in the presence of primary amines (1981) (27)
- Creation of a Synthetic Ligand for Mitochondrial DNA Sequence Recognition and Promoter-Specific Transcription Suppression. (2017) (27)
- Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex. (2018) (27)
- Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element (2006) (27)
- Next‐Generation Sequencing Studies Guide the Design of Pyrrole‐Imidazole Polyamides with Improved Binding Specificity by the Addition of β‐Alanine (2014) (27)
- Construction of integrated gene logic-chip (2018) (27)
- Development of a Vivid FRET System Based on a Highly Emissive dG-dC Analogue Pair. (2017) (27)
- DNA ligand designed to antagonize EBNA1 represses Epstein–Barr virus‐induced immortalization (2011) (27)
- Alkylation of template strand of coding region causes effective gene silencing (2006) (27)
- Preferential C1′ Hydrogen Abstraction by a Uracilyl Radical in a DNA-RNA Hybrid (1997) (27)
- Torsional Constraints of DNA Substrates Impact Cas9 Cleavage. (2016) (27)
- Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. (2014) (26)
- Impact of Aspiration Pneumonia on the Clinical Course of Progressive Supranuclear Palsy: A Retrospective Cohort Study (2015) (26)
- Pharmacokinetic modeling and prediction of plasma pyrrole-imidazole polyamide concentration in rats using simultaneous urinary and biliary excretion data. (2009) (26)
- Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA. (2013) (26)
- DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels. (2018) (26)
- Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson’s disease (2018) (26)
- SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome (2012) (26)
- Complexing DNA Origami Frameworks through Sequential Self-Assembly Based on Directed Docking. (2018) (26)
- Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats. (2014) (26)
- Detection of triplet repeat sequences in the double-stranded DNA using pyrene-functionalized pyrrole-imidazole polyamides with rigid linkers. (2008) (25)
- Sequence-specific alkylation by Y-shaped and tandem hairpin pyrrole-imidazole polyamides. (2008) (25)
- DNA Nanostructures for Targeted Antimicrobial Delivery (2020) (25)
- Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants (2012) (25)
- A Photoregulated DNA-Based Rotary System and Direct Observation of Its Rotational Movement. (2017) (25)
- Early use of donepezil against psychosis and cognitive decline in Parkinson’s disease: a randomised controlled trial for 2 years (2018) (25)
- Design of a new fluorescent probe: pyrrole/imidazole hairpin polyamides with pyrene conjugation at their γ-turn. (2013) (25)
- Effect of ATRX and G‐Quadruplex Formation by the VNTR Sequence on α‐Globin Gene Expression (2016) (25)
- Chemistry of neocarzinostatin-mediated cleavage of oligonucleotides. Competitive ribose C5' and C4' hydroxylation (1992) (25)
- Solid-supported DNA for asymmetric synthesis: a stepping-stone toward practical applications. (2013) (24)
- Therapeutic gene regulation using pyrrole-imidazole polyamides. (2019) (24)
- Sequence-Specific DNA Alkylation by Hybrid Molecules between Segment A of Duocarmycin A and Pyrrole/Imidazole Diamide. (1999) (24)
- Transcription regulation system mediated by mechanical operation of a DNA nanostructure. (2012) (24)
- The distance between donor and acceptor affects the proportion of C1' and C2' oxidation products of DNA in a BrU-containing excess electron transfer system. (2010) (23)
- Highly Cooperative DNA Dialkylation by the Homodimer of Imidazole−Pyrrole Diamide−CPI Conjugate with Vinyl Linker (2000) (23)
- Apoprotein-assisted unusual cyclization of neocarzinostatin chromophore (1994) (23)
- Tandem trimer pyrrole-imidazole polyamide probes targeting 18 base pairs in human telomere sequences. (2015) (22)
- Strategies To Modulate Heritable Epigenetic Defects in Cellular Machinery: Lessons from Nature (2012) (22)
- Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells. (2015) (22)
- Biomimetic Artificial Epigenetic Code for Targeted Acetylation of Histones. (2018) (22)
- Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'. (2013) (22)
- Development of pyrrole-imidazole polyamide for specific regulation of human aurora kinase-A and -B gene expression. (2008) (22)
- [Loss of dendritic spines in hippocampal CA1 pyramidal cells in senescence accelerated mouse (SAM)--a quantitative Golgi study]. (1987) (22)
- Chemistry of neocarzinostatin-mediated degradation of d(GCATGC). Mechanism of spontaneous thymine release (1989) (22)
- Carbon-13 Nuclear Magnetic Resonance Spectra of a-Ribonucleosides (1974) (22)
- Perylene-conjugated pyrrole polyamide as a sequence-specific fluorescent probe. (2008) (22)
- A novel photoreaction of thymidine with lysine. Photoinduced migration of thymine from DNA to lysine (1981) (22)
- Photoreactions of Nucleic Acids and Their Constituents with Amino Acids and Related Compounds (1991) (22)
- Efficient C2'α-hydroxylation of deoxyribose in protein-induced Z-form DNA (2003) (22)
- Unique charge transfer properties of the four-base pi-stacks in Z-DNA. (2003) (22)
- The origin of enantioselectivity for intramolecular Friedel-Crafts reaction catalyzed by supramolecular Cu/DNA catalyst complex (2014) (22)
- Replication in vitro and cleavage by restriction endonuclease of 5-formyluracil- and 5-hydroxymethyluracil-containing oligonucleotides. (1999) (22)
- Eukaryotic DNA Polymerases α, β and ε Incorporate Guanine Opposite 2,2,4‐Triamino‐5(2H)‐oxazolone (2009) (22)
- I-motif and quadruplex-based device that can control a protein release or bind and release small molecule to influence biological processes. (2007) (21)
- Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure. (2016) (21)
- Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells (2017) (21)
- Direct AFM observation of an opening event of a DNA cuboid constructed via a prism structure. (2011) (21)
- Structures of cobalt(III)-pepleomycin and cobalt(III)-deglycopepleomycin (green forms) determined by NMR studies. (1997) (21)
- Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs. (2018) (21)
- Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA (2014) (21)
- G-quadruplex-binding ligand-induced DNA synapsis inside a DNA origami frame (2014) (21)
- Detection of CAG repeat DNA sequences by pyrene-functionalized pyrrole-imidazole polyamides. (2007) (20)
- Translesion synthesis by human DNA polymerase eta across oxidative products of guanine. (2004) (20)
- Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine (2010) (20)
- Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates. (2003) (20)
- STABILIZATION OF HOOGSTEEN BASE PAIRING BY INTRODUCTION OF NH2 GROUP AT THE C8 POSITION OF ADENINE (1998) (20)
- Genomic analysis uncovers prognostic and immunogenic characteristics of ferroptosis for clear cell renal cell carcinoma (2021) (20)
- Pharmacokinetics of pyrrole‐imidazole polyamides after intravenous administration in rat (2009) (20)
- Characterization of 2-hydroxyadenine DNA glycosylase activity of Escherichia coli MutY protein (2002) (20)
- Photoreactivation of DNA by an Archaeal nucleoprotein Sso7d (2006) (20)
- G-quadruplexes as versatile scaffolds for catalysis. (2019) (20)
- Unusual Topological RNA Architecture with an Eight-Stranded Helical Fragment Containing A-, G-, and U-Tetrads. (2017) (19)
- Duplex DNA is Weakened in Nanoconfinement. (2020) (19)
- Sequence-specific protection of plasmid DNA from restriction endonuclease hydrolysis by pyrrole-imidazole-cyclopropapyrroloindole conjugates. (2002) (19)
- The new models of the human telomere DNA in K+ solution revealed by NMR analysis assisted by the incorporation of 8-bromoguanines. (2006) (19)
- Helical DNA origami tubular structures with various sizes and arrangements. (2014) (19)
- Induction of stem-cell-derived functional neurons by NanoScript-based gene repression. (2015) (19)
- Single strand DNA catenane synthesis using the formation of G-quadruplex structure. (2012) (19)
- Identification of high excision capacity for 5-hydroxymethyluracil mispaired with guanine in DNA of Escherichia coli MutM, Nei and Nth DNA glycosylases. (2003) (19)
- Enantioselective DNA alkylation by a pyrrole-imidazole S-CBI conjugate. (2004) (19)
- Inducing Stem Cell Myogenesis Using NanoScript. (2015) (19)
- Folding pathways of human telomeric hybrid G-quadruplex structure. (2007) (18)
- An efficient, one-pot synthesis of 2-deoxy-2-[18f]fluoroacetamido-d-glucopyranose ( n -[18f]fluoroacetyl-d-glucosamine), potential diagnostic imaging agent (1989) (18)
- DNA Origami: Synthesis and Self‐Assembly (2012) (18)
- Modulation of Sequence Specificity of Duocarmycin-Dependent DNA Alkylation by Pyrrole-Imidazole Triamides (1999) (18)
- Enhanced cytotoxicity in a Z-photoisomer of a benzopyran derivative of propolis. (2000) (18)
- Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors. (2017) (18)
- Photoinduced reactions. 151. Isolation and characterization of a thymine-lysine adduct in UV-irradiated nuclei. The role of thymine-lysine photoaddition in photo-cross-linking of proteins to DNA (1983) (18)
- Nanochannel-Confined TAMRA-Polypyrrole Stained DNA Stretching by Varying the Ionic Strength from Micromolar to Millimolar Concentrations (2018) (18)
- KsgA, a 16S rRNA adenine methyltransferase, has a novel DNA glycosylase/AP lyase activity to prevent mutations in Escherichia coli (2009) (18)
- Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli (2001) (18)
- Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (2015) (18)
- Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI. (2010) (18)
- Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells. (2015) (17)
- Observation of dislocations in hen egg‐white lysozyme crystals by synchrotron monochromatic‐beam X‐ray topography (2009) (17)
- Direct Observation of H3-H4 Octasome by High-Speed AFM. (2018) (17)
- Specific adenine alkylation by pyrrole-imidazole CBI conjugates. (2005) (17)
- Programmable formation of catalytic RNA triangles and squares by assembling modular RNA enzymes (2017) (17)
- PHOTOINDUCED REACTIONS. 158. PHOTOCHEMICAL HYDROGEN‐DEUTERIUM EXCHANGE REACTION OF TRYPTOPHAN. THE ROLE OF NONRADIATIVE DECAY OF SINGLET TRYPTOPHAN (1984) (17)
- Specific alkylation of human telomere repeat sequences by a tandem-hairpin motif of pyrrole-imidazole polyamides with indole-seco-CBI. (2014) (17)
- The androgen receptor as putative therapeutic target in hormone-refractory prostate cancer. (2007) (17)
- A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts (2015) (17)
- Cyanide metabolism in motor neuron disease (1985) (17)
- Telomere Visualization in Tissue Sections using Pyrrole–Imidazole Polyamide Probes (2016) (17)
- Base Pair Recognition of the Stereochemically α-Substituted γ-Turn of Pyrrole/Imidazole Hairpin Polyamides (2006) (17)
- Advances in DNA Origami–Cell Interfaces (2020) (17)
- Photoreaction of iodouracil in DNA duplex; C–I bond is cleaved via two different pathways ‘homolysis and heterolysis’ (2008) (16)
- 13C nuclear magnetic resonance spectra of glucobioses (1971) (16)
- Hypoxia‐inducible factor 1α may be a marker for vasculitic neuropathy (2007) (16)
- Determination of pyrrole-imidazole polyamide in rat plasma by liquid chromatography-tandem mass spectrometry. (2009) (16)
- Similarities and Differences between RNA and DNA Double-Helical Structures in Circular Dichroism Spectroscopy: A SAC-CI Study. (2016) (16)
- GC-->CG transversion mutation might be caused by 8-oxoguanine oxidation product. (2000) (16)
- Long range carbon–proton coupling constants in pyridine (1974) (16)
- Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing (2016) (16)
- Synthesis and Biological Properties of Sequence-Specific DNA-Alkylating Pyrrole—Imidazole Polyamides (2007) (16)
- DNA cleavage reaction of antitumour antibiotic, kapurimycin A3, with deoxytetranucleotide d(CGCG)2. (1991) (16)
- Determination of Anomeric Configuration of Furanoside Derivatives by Carbon-13 NMR (1974) (15)
- Discrimination between T/A and A/T Base Pairs of Pyrrole‐Imidazole Polyamides Substituted with Chiral β‐Hydroxy‐γ‐Aminobutyric Acid/β‐Alanine Pairs (2012) (15)
- CGmCGCG is a versatile substrate with which to evaluate Tet protein activity. (2014) (15)
- A new procedure for determining thymine residues in DNA sequencing. Photoinduced cleavage of DNA fragments in the presence of spermine. (1984) (15)
- Structural and functional analysis of proteins by high-speed atomic force microscopy. (2012) (15)
- Delayed surgical treatment for a traumatic bilateral cervical facet joint dislocation using a posterior-anterior approach: a case report (2013) (15)
- Inside Cover: Programmed‐Assembly System Using DNA Jigsaw Pieces (Chem. Eur. J. 18/2010) (2010) (15)
- Requirement of beta-alanine components in sequence-specific DNA alkylation by pyrrole-imidazole conjugates with seven-base pair recognition. (2008) (15)
- Bleomycin-mediated degradation of aristeromycin-containing DNA. Novel dehydrogenation activity of ironII-bleomycin (1991) (15)
- Investigation of B-Z transitions with DNA oligonucleotides containing 8-methylguanine (2014) (15)
- Sequence-specific electron injection into DNA from an intermolecular electron donor (2013) (15)
- RNA binding properties of novel gene silencing pyrrole-imidazole polyamides. (2013) (15)
- Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control (2014) (15)
- Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex in solution: the protein-induced DNA kink causes intrastrand hydrogen abstraction from the 5-methyl of thymine at the 5' side. (2002) (14)
- Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers. (2014) (14)
- Control of the two-dimensional crystallization of DNA origami with various loop arrangements. (2013) (14)
- Approach to the Investigation of Nucleosome Structure by Using the Highly Emissive Nucleobase th dG-tC FRET Pair. (2018) (14)
- Landscape of immune cell infiltration in clear cell renal cell carcinoma to aid immunotherapy (2021) (14)
- Submolecular dissection reveals strong and specific binding of polyamide–pyridostatin conjugates to human telomere interface (2019) (14)
- Specific alkylation of human telomere repeats by hairpin pyrrole-imidazole polyamide. (2003) (14)
- Photochemical reaction between tryptophan and thymine (1984) (14)
- Photocontrollable sequence-specific DNA alkylation by a pyrrole-imidazole polyamide seco-CBI conjugate. (2011) (14)
- Synthesis of 18F-labelled 2-deoxy-2-fluoro-d-galactopyranose using the acetyl hypofluorite procedure (1987) (14)
- Programming Rotary Motions with a Hexagonal DNA Nanomachine. (2019) (14)
- Formation of farnesal and 3-hydroxy-2,3-dihydrofarnesal from farnesol by protoplasts of Botryococcus braunii. (1993) (13)
- Alkylation of a human telomere sequence by heterotrimeric chlorambucil PI polyamide conjugates. (2010) (13)
- Development of Antibody–Oligonucleotide Complexes for Targeting Exosomal MicroRNA (2020) (13)
- RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice. (2018) (13)
- The most electron-donating sites in duplex DNA: guanine-guanine stacking rule. (1995) (13)
- C-H to N substitution dramatically alters the sequence-specific DNA alkylation, cytotoxicity, and expression of human cancer cell lines. (2004) (13)
- Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates. (2015) (13)
- Sequence preference and structural heterogeneity of BZ junctions (2018) (13)
- Ntg1 and Ntg2 proteins as 5‐formyluracil‐DNA glycosylases/AP lyases in Saccharomyces cerevisiae (2003) (13)
- User-friendly Synthesis and Photoirradiation of a Flavin-linked Oligomer (2007) (13)
- Triple Helix Formation in a Topologically Controlled DNA Nanosystem. (2016) (13)
- 13C and 1H Nuclear Magnetic Resonance for Structural Investigation of Some Glucans (1975) (13)
- Synthesis of pyrrole-imidazole polyamide seco-1-chloromethyl-5-hydroxy-1,2-dihydro-3h-benz[e]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence. (2012) (13)
- STRUCTURE OF THE ALKALI‐LABILE PRODUCT FORMED DURING IRON(II)‐BLEOMYCIN‐MEDIATED DNA STRAND SCISSION (1985) (13)
- Cooperative alkylation of double-strand human telomere repeat sequences by PI polyamides with 11-base-pair recognition based on a heterotrimeric design. (2009) (13)
- Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide. (2019) (12)
- Molecular design of sequence specific DNA alkylating agents. (2009) (12)
- Sequence-specific DNA interstrand cross-linking by imidazole--pyrrole CPI conjugate. (2001) (12)
- Recombinant Schizosaccharomyces pombe Nth1 protein exhibits DNA glycosylase activities for 8-oxo-7,8-dihydroguanine and thymine residues oxidized in the methyl group. (2007) (12)
- Thiol-activated sodium borohydride reduction of carboxylate ester (1975) (12)
- A Multi‐target Small Molecule for Targeted Transcriptional Activation of Therapeutically Significant Nervous System Genes (2016) (12)
- Folding pathways of hybrid-1 and hybrid-2 G-quadruplex structures. (2008) (12)
- Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs. (2018) (12)
- Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates. (2014) (12)
- Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions. (2017) (12)
- Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome (2016) (11)
- Binding of a Telomestatin Derivative Changes the Mechanical Anisotropy of a Human Telomeric G-Quadruplex. (2018) (11)
- Ligand‐Mediated G‐Quadruplex Induction in a Double‐Stranded DNA Context by Cyclic Imidazole/Lysine Polyamide (2016) (11)
- Nucleotide excision repair of 5-formyluracil in vitro is enhanced by the presence of mismatched bases. (2004) (11)
- A concise one‐pot synthesis of [18F]fluoromisonidazole from (2R)‐(−)‐glycidyl tosylate (1996) (11)
- Studying RNAP-promoter interactions using atomic force microscopy. (2015) (11)
- The Stereochemistry of Hydrogenation with Tris(triphenylphosphine)chlororhodium (1972) (11)
- The orientation of the ends of G-quadruplex structures investigated using end-extended oligonucleotides. (2009) (11)
- Long-read sequencing identifies GGC repeat expansion in human-specific NOTCH2NLC associated with neuronal intranuclear inclusion disease (2019) (11)
- A convenient synthesis of D‐[1‐11C]glucopyranose and D‐[1‐11C]galactopyranose using diborane (1989) (11)
- TAMRA-polypyrrole for A/T sequence visualization on DNA molecules (2018) (11)
- Enhancement in antioxidant‐based hepatoprotective activity of trolox by its conjugation to lactosylphenylpyranoside (1992) (11)
- Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation. (2011) (11)
- Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes. (2010) (11)
- Organic chemical approach to photo-crosslinks of nucleic acids to proteins (1980) (11)
- Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe. (2014) (11)
- The chemical compound bubblin induces stomatal mispatterning in Arabidopsis by disrupting the intrinsic polarity of stomatal lineage cells (2017) (11)
- Optimization and validation of a high-performance liquid chromatographic method with UV detection for the determination of pyrrole-imidazole polyamides in rat plasma. (2007) (11)
- A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA. (2015) (10)
- Hypoxia-inducible factor 1alpha may be a marker for vasculitic neuropathy. (2007) (10)
- Structural and functional characterizations of the G-quartet and i-motif elements in retinoblastoma susceptibility genes (Rb). (2005) (10)
- Different profiles of onion bulb in CIDP and CMT1A in relation to extracellular matrix. (2013) (10)
- Oligonucleotides Containing a Radical Trap: The Trapping of Deoxyribose C4' Radical in Bleomycin-Mediated Reactions (1994) (10)
- Amplification of fluorescent DNA through enzymatic incorporation of a highly emissive deoxyguanosine analogue (2014) (10)
- Triggering nucleic acid nanostructure assembly by conditional kissing interactions (2017) (10)
- Intrastrand 2′β hydrogen abstraction of 5′-adjacent deoxyguanosine by deoxyuridin-5-yl in Z-form DNA (1999) (10)
- Comparative Analysis of DNA‐Binding Selectivity of Hairpin and Cyclic Pyrrole‐Imidazole Polyamides Based on Next‐Generation Sequencing (2016) (9)
- Development of a visible nanothermometer with a highly emissive 2′-O-methylated guanosine analogue (2015) (9)
- A Near-Infrared Fluorogenic Pyrrole-Imidazole Polyamide Probe for Live-Cell Imaging of Telomeres. (2020) (9)
- Facile synthesis of puromycin-tethered oligonucleotides at the 3′-end (1998) (9)
- Regulation of B-Z conformational transition and complex formation with a Z-form binding protein by introduction of constraint to double-stranded DNA by using a DNA nanoscaffold. (2013) (9)
- Discrimination of hairpin polyamides with an alpha-substituted-gamma-aminobutyric acid as a 5'-TG-3' reader in DNA minor groove. (2006) (9)
- Direct observation and analysis of TET-mediated oxidation processes in a DNA origami nanochip (2020) (9)
- Formation of farnesyl oleate and three other farnesyl fatty acid esters by cell-free extracts from Botryococcus braunii B race (1994) (9)
- Construction and characterization of Cy3- or Cy5-conjugated hairpin pyrrole-imidazole polyamides binding to DNA in the nucleosome. (2014) (9)
- Sequence dependent photoreduction of 5-bromouracil-contaning oligonucleotides via electron transfer (1998) (9)
- Modular DNA-based hybrid catalysts as a toolbox for enantioselective hydration of α,β-unsaturated ketones. (2019) (9)
- Molecular Characteristics of DNA-Alkylating PI Polyamides Targeting RUNX Transcription Factors. (2019) (9)
- Double β-alanine Substitutions Incorporated in 12-ring Pyrrole-Imidazole Polyamides for Lengthened DNA Minor Groove Recognition (2015) (9)
- The recognition of higher-order G-quadruplex by chiral cyclic-helicene molecules. (2006) (9)
- Deglyco-peplomycin metal complexes on DNA fibers: a role of the sugar moiety for the stability and the orientation of the complexes (2002) (9)
- Non-invasive Regulation of Cellular Morphology Using a Photoswitchable Mechanical DNA Polymer. (2021) (9)
- 5-Exo versus 6-endo cyclization of nucleoside 2-sila-5-hexenyl radicals: reaction of 6-(bromomethyl)dimethylsilyl 1',2'-unsaturated uridines. (2005) (9)
- T-loop formation by human telomeric G-quadruplex. (2007) (9)
- New Size-Expanded Fluorescent Thymine Analogue: Synthesis, Characterization, and Application. (2019) (9)
- Synthesis of methyl 4,6-O-benzylidene-2,3-dideoxy-β-D-erythro-hex-2-enopyranoside by the Tipson-Cohen reaction (1976) (9)
- G-Quadruplex Induction by the Hairpin Pyrrole-Imidazole Polyamide Dimer. (2017) (8)
- Direct Observation of the Double-Stranded DNA Formation through Metal Ion-Mediated Base Pairing in the Nanoscale Structure. (2018) (8)
- Preferential 5-Methylcytosine Oxidation in the Linker Region of Reconstituted Positioned Nucleosomes by Tet1 Protein. (2016) (8)
- DNA Interaction and Cytotoxicity of Cyclometalated Ruthenium(II) Complexes as Potential Anticancer Drugs. (2016) (8)
- Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay (2016) (8)
- Investigating Nucleosome Accessibility for MNase, FeII Peplomycin, and Duocarmycin B2 by Using Capillary Electrophoresis (2018) (8)
- Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. (2016) (8)
- Photoreaction of thymidine with primary amines. Application to specific modification of DNA. (1981) (8)
- Chemical probe-based Nanopore Sequencing to Selectively Assess the RNA modifications (2020) (8)
- Structure of A1-barrigenol and R1-barrigenol (1967) (8)
- AFM analysis of changes in nucleosome wrapping induced by DNA epigenetic modification. (2014) (8)
- A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus. (2020) (8)
- C-13 NMR Spectra of Aspulvinones (1979) (8)
- Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity. (2010) (8)
- A Photocaged DNA Nanocapsule for Controlled Unlocking and Opening inside the Cell. (2019) (8)
- Sequence-specific alkylation of DNA by duocarmycin A and its novel derivatives bearing PY/IM polyamides. (1999) (8)
- Sequence-Specific PI Polyamides Make It Possible to Regulate DNA Structure and Function (2020) (7)
- Highly sensitive and selective mercury sensor based on mismatched base pairing with dioxT. (2019) (7)
- [Falls in peripheral neuropathy]. (2005) (7)
- Development of a molecule-recognized promoter DNA sequence for inhibition of HER2 expression (2009) (7)
- Chemical Control System of Epigenetics. (2018) (7)
- Construction and Characterization of Cy3- or Cy5-Conjugated Hairpin Pyrrole/Imidazole Polyamides Binding to DNA in the Nucleosome (2014) (7)
- Nucleosome Assembly Alters the Accessibility of the Antitumor Agent Duocarmycin B2 to Duplex DNA. (2016) (7)
- Chemical biology that controls DNA structure and function. (2007) (7)
- Linking two DNA duplexes with a rigid linker for DNA nanotechnology (2015) (7)
- Detecting Distal Radial Fractures from Wrist Radiographs Using a Deep Convolutional Neural Network with an Accuracy Comparable to Hand Orthopedic Surgeons (2021) (7)
- Effective Anti-miRNA Oligonucleotides Show High Releasing Rate of MicroRNA from RNA-Induced Silencing Complex. (2017) (7)
- Direct Observation and Analysis of the Dynamics of the Photoresponsive Transcription Factor GAL4. (2019) (7)
- Lumbopelvic Fixation for Sacral Insufficiency Fracture Presenting with Sphincter Dysfunction (2019) (7)
- Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences. (2015) (7)
- Chemical Modification of a Synthetic Small Molecule Boosts Its Biological Efficacy against Pluripotency Genes in Mouse Fibroblasts (2014) (7)
- Stacking interaction between tryptophan and uracil in a synthetic model compound (1985) (7)
- The anomeric equilibrium of glucose in acidic and basic media. (1980) (7)
- Synthesis, Photophysical Properties, and Enzymatic Incorporation of an Emissive Thymidine Analogue (2017) (7)
- A lock-and-key mechanism for the controllable fabrication of DNA origami structures. (2014) (7)
- Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA. (2015) (7)
- Genome‐Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High‐Throughput Sequencing (2016) (7)
- DNA Interstrand Crosslinks by H‐pin Polyamide (S)‐seco‐CBI Conjugates (2017) (7)
- Automatic Peptide Synthesizer (1968) (7)
- Recognition by Nonaromatic and Stereochemical Subunit‐Containing Polyamides of the Four Watson–Crick Base Pairs in the DNA Minor Groove (2012) (6)
- Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain. (2021) (6)
- The application of fluorescence-conjugated pyrrole/imidazole polyamides in the characterization of protein-DNA complex formation. (2016) (6)
- Pyrazolotropolones and Their Derivatives (1966) (6)
- Design of photochemical DNA-cleaving molecules via electron transfer (1997) (6)
- The Conformational Study of Two Carbocyclic Nucleosides: Why Carbocyclic Nucleic Acids (CarNAs) Form More Stable Duplexes with RNA than DNA Does (2002) (6)
- The chemospecific reduction of aldehyde and ketone with sodium borohydride in the presence of thiol (1977) (6)
- Syntheses and reactions of deuterated troponoids (1965) (6)
- Oligomerization of a modular ribozyme assembly of which is controlled by a programmable RNA-RNA interface between two structural modules. (2019) (6)
- Photocontrolled DNA origami assembly using two photoswitches. (2020) (6)
- Catalytic activities of hammerhead ribozymes with a triterpenoid linker instead of stem/loop II (1996) (6)
- Binding of distamycin A to UV-damaged DNA. (2004) (6)
- Distamycin A enhances the cytotoxicity of duocarmycin A and suppresses duocarmycin A-induced apoptosis in human lung carcinoma cells. (2007) (6)
- Chemical Approaches to the Development of Artificial Transcription Factors Based on Pyrrole‐Imidazole Polyamides (2020) (6)
- Efficient generation of 2'-deoxyuridin-5-yl at 5'-(G/C)AA(X)U(X)U-3' (X = Br, I) sequences in duplex DNA under UV-irradiation. (2004) (6)
- Effects of Physical Damage in the Intermediate Phase on the Progression of Amyloid bFibrillization. (2019) (6)
- Carbon-13 NMR Study of Saccharides (1978) (6)
- Reactivity of 5‐Halopyrimidines in Nucleic Acids (2009) (6)
- Alteration of epigenetic program to recover memory and alleviate neurodegeneration: prospects of multi-target molecules. (2014) (6)
- Photochemical Approach to Probing Different DNA Structures (2006) (5)
- Photocycloadditions of Benzophenone with 6-Methylenetricyclo[3.2.1.02,7]oct-3-en-8-one and Its Related Compounds. Di-π-methane Photorearrangement of the Primary Photocycloadducts (1982) (5)
- A Combination of Visible-light Photoredox and Metal Catalysis for the Mannich-type Reaction of N-Aryl Glycine Esters (2017) (5)
- A rapid synthesis of [fluoroacetyl-18F]fluoromelatonin (Nω-[18F]fluoroacetyl-5-methoxytryptamine), a potential diagnostic imaging agent (1993) (5)
- DNA‐Based Hybrid Catalysts for Asymmetric Organic Synthesis (2010) (5)
- Histidine-conjugated DNA as a biomolecular depot for metal ions (2020) (5)
- Base pair recognition of the stereochemically alpha-substituted gamma-turn of pyrrole/imidazole hairpin polyamides. (2006) (5)
- Cerebellar ataxia with glutamic aciduria (1991) (5)
- Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA (2015) (5)
- Photoreactivities of 5-bromouracil-containing RNAs. (2013) (5)
- A Surgical Treatment for Adult Muscular Torticollis (2013) (5)
- Evaluation of alkylating pyrrole-imidazole polyamide conjugates by a novel method for high-throughput sequencer. (2018) (5)
- Identification of Sequence Specificity of 5‐Methylcytosine Oxidation by Tet1 Protein with High‐Throughput Sequencing (2016) (5)
- Recognition of DNA Sequences by Pyrrole-Imidazole Polyamide (2000) (5)
- Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation (2018) (5)
- A rapid and efficient synthesis of 2‐deoxy‐2‐[18F]fluoroacetamido‐D‐mannopyranose and ‐D‐galactopyranose (1990) (5)
- The Solid Phase Synthesis of 19-Tyrosine Melittin (1972) (5)
- Steric and electrostatic effects on the elimination of 2- and 3-sulphonyloxy-groups from methyl 4,6-O–benzylidenehexopyranosides (1977) (5)
- Regio‐Controlled Hydrogen‐Deuterium Exchange of Biologically Important Indoles Under UV‐Irradiation. (1986) (5)
- The solvomercuration, bromination, and related reactions of 1,5-dimethyl-6-methylenetricyclo(3.2.1.02,7)oct-3-en-8-one and its related compounds. (1982) (5)
- DNA Origami as a Tool in the Targeted Destruction of Bacteria (2019) (4)
- Chemical probe-based Nanopore direct RNA sequencing method to selectively assess the pseudouridine and inosine modifications (2020) (4)
- DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells. (2020) (4)
- Conformational analysis. LXXII. Solvolysis studies with the 5-phenylcyclooctanol system (1971) (4)
- New synthetic route to 2′,3′-unsaturated pyranosyl thymine from the corresponding O2,2′-cyclonucleoside (1975) (4)
- Activation of neocarzinostatin-chromophore by 4-hydroxythiophenol: Intramolecular radical trapping of biradical intermediate (1994) (4)
- An efficient synthesis of Nω-[18F]fluoroacetylserotonin (Nω-[18F]fluoroacetyl-5-hydroxytryptamine) (1994) (4)
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- An efficient synthesis of 2‐ [ carbonyl‐ 11C]acetamido‐2‐deoxy‐D‐glucopyranose (N‐[carbonyl‐11C]acetyl‐D‐glucosamine) (1991) (2)
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- Conformational analysis. LXVI. Studies involving the 3-tert-butylcyclooctyl ring system (1970) (2)
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- An RNA Triangle with Six Ribozyme Units Can Promote a Trans-Splicing Reaction through Trimerization of Unit Ribozyme Dimers (2021) (2)
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- The molecular-thermometer based on B-Z transition of DNA. (2004) (1)
- Enhanced Immunostimulatory Activity of Covalent DNA Dendrons (2021) (1)
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- Targeted Epigenetic Induction of Mitochondrial Biogenesis Enhances Antitumor Immunity in Mouse Model (2020) (1)
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- Photoreaction of 5-bromouracil-containing DNA. (1995) (1)
- Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation. (2022) (1)
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- Strong and Specific Recognition of CAG/CTG Repeat DNA (5’‐dWGCWGCW‐3’) by a Cyclic Pyrrole‐Imidazole Polyamide (2021) (1)
- 1M1524 Constructing DNA-kinesin hybrid-nanomachine using the DNA-tile scaffold(Molecular motor 2,The 49th Annual Meeting of the Biophysical Society of Japan) (2011) (1)
- Switching Off Cancer-Causing Telomerase Using Small Molecules. (2019) (1)
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- 3P-0891 Development of pyrrole-imidazole polyamides targeting TGF-β1 promoter as a gene therapy for the arterial proliferative diseases (2003) (0)
- SYNTHESIS OF A (2,3-DIDEOXYGLYC-2-ENOPYRANOSYL)THYMINE AND A (2,3-DIDEOXYGLYCOPYRANOSYL)THYMINE VIA A 2,2′-ANHYDRO-NUCLEOSIDE (1977) (0)
- Pyrrole-Imidazole Polyamides as artificial genetic switches (2020) (0)
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- PHOTOCHEMICAL CYCLOADDITION OF BENZOPHENONE WITH 1,5-DIMETHYL-6-METHYLENETRICYCLO(3.2.1.02,7)OCT-3-EN-8-ONE AND A RELATED ALCOHOL- A STRIKING SUBSTITUENT EFFECT ON THE PRODUCT COMPOSITION (1978) (0)
- Metals in medicineOxidative DNA strand scission by metallo bleomycins (1989) (0)
- Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate (2017) (0)
- P.1.k.001 Clinical conditions relevant to the depressive mental states of Japanese patients with subacute myelo-optic neuropathy (SMON) (2015) (0)
- DNA origami nanostructures as a tool for the targeted destruction of bacteria (2019) (0)
- A photocaged DNA nanocapsule for delivery and manipulation in cells. (2020) (0)
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- Deciphering DNA‐Based Asymmetric Catalysis Through Intramolecular Friedel—Crafts Alkylations. (2013) (0)
- Photoreactivity of 5-iodouracil-containing DNA-Z alpha complex. (2001) (0)
- Characterization of the Releasing Profile of MicroRNA from RISC Using Anti-miRNA Oligonucleotides (2017) (0)
- Molecular design of hairpin pyrrole-imidazole polyamides possessing sequence specific DNA alkylating moiety. (2003) (0)
- Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs (2021) (0)
- Nanoscopic observation of a DNA crystal surface and its dynamic formation and degradation using atomic force microscopy. (2021) (0)
- 3PT111 Construction and functional analysis of DNA origami base DNA-RNAP hybrid nanomachine(The 50th Annual Meeting of the Biophysical Society of Japan) (2012) (0)
- Cooperative alkylation by duocarmycin A-distamycin A heterodimer. (1997) (0)
- RUNX1 regulates KIT expression and is a novel therapeutic target in human mast-cell diseases. (2017) (0)
- Integrated analysis of coexpression and competitive endogenous RNA networks identified survival-related genes in gastrointestinal tumors (2021) (0)
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- Self-assembly of Two-dimensional DNA Origami Lattices on Lipid Bilayer Membranes (2019) (0)
- Composes alkylant une sequence de base specifique d'adn, et procede de synthese desdits composes (1999) (0)
- 20aXB-1 Dislocation structures of the HEW-lysozyme crystals with some polymorphisms (2007) (0)
- Photochemistry of 5‐Bromouracil‐ or 5‐Iodouracil‐Containing DNA: Probe for DNA Structure and Charge Transfer Along DNA (2010) (0)
- Synthesis of Nw-[18F]Fluoroacetyl-5-hydroxytryptamine from Ethyl p-Tosyloxyacetate (1993) (0)
- Guanine oxidation product, 2-aminoimidazolone, may cause G:C->C:G transversion mutation (2000) (0)
- PHOTOINDUCED REACTIONS. 159. PHOTOCHEMICAL REACTION BETWEEN TRYPTOPHAN AND THYMINE (1984) (0)
- NMR STRUCTURE OF THE GAACTGGTTC/TRI-IMIDAZOLE POLYAMIDE COMPLEX (1999) (0)
- Identification of Human Nei Protein as a 5-Formyluracil DNA Glycosylase/AP lyase (2002) (0)
- 3SCA-01 Chemical Biology that Controls DNA Structure and Function : DNA Origami and Artificial Genetic Switch(3SCA Frontier of functional nucleic acids toward elucidation of biological events and nucleic acid medicine,Symposium) (2013) (0)
- COBALT(III)-PEPLOMYCIN COMPLEX DETERMINED BY NMR STUDIES (1999) (0)
- DNA as a Chiral Scaffold for Asymmetric Catalysis (2014) (0)
- Analysis of guanine oxidation product via electron transfer in 5'-d(TTGGTA)-3'. (1997) (0)
- RUNX1 Enhances Leukemia Cell Engraftment in the Vascular Niche through up-Regulating E-Selectin (2017) (0)
- 1P316 Rational design of orthogonal gene transcription nano device on DNA origami(28. Bioengineering,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)) (2014) (0)
- P.5.f.001 Time course of the depressive mental states in Japanese patients with subacute myelo-optic neuropathy (SMON) (2016) (0)
- dentification of 5-Formyluracil DNA Glycosylase/AP Lyase Activity of S. cerevisiae Ntg1 and Ntg2 Proteins (2001) (0)
- Title Deciphering the genomic targets of alkylating polyamideconjugates using high-throughput sequencing (2019) (0)
- PD20 DNA STRAND SCISSION BY NEOCARZINOSTATIN : REACTION OF SELF-COMPLEMENTARY OLIGONUCLOETIDE (1988) (0)
- Synthesis of 3-aminotropone (1968) (0)
- Title Deciphering DNA-based asymmetric catalysis throughintramolecular Friedel-Crafts alkylations (2017) (0)
- 3P306 Construction and functional analysis of DNA origami base DNA-RNAP hybrid nanomachine(28.Bioengineering,Poster,The 51st Annual Meeting of the Biophysical Society of Japan) (2013) (0)
- A Chemical Synthesis of 2-Deoxy-2-[18F]fluoroacetamido-D-glucopyranose (N-[18F]Fluoroacetyl-D-glucosamine) from [18F]Fluoride (1989) (0)
- RUNX inhibitor suppresses graft‐versus‐host disease through targeting RUNX‐NFATC2 axis (2021) (0)
- Bis(hydroperoxy)naphthaldiimide as a “Photo-Fenton-Reagent”: Sequence- Specific Photochemical DNA Cleavage. (1991) (0)
- Cluster Regulation of RUNX Family By Gene Switch Triggers a Profound Tumor Regression of Diverse Origins (2016) (0)
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- Structure of DNA containing aristeromycin analog. (1997) (0)
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- Title Protein-driven RNA nanostructured devices that function invitro and control mammalian cell fate (2018) (0)
- Identification of Binding Activities to 8-Oxoguanine-Containing Oligonucleotides in Extracts Prepared fromSaccharomyces cerevisiae (2001) (0)
- Controlling the function of genes and biologically active nucleic acids. (2019) (0)
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- Mo-P3:225 Pyrrole-imidazole polyamide targeting human lectin-like oxidized LDL receptor 1 gene reduced endothelial cell apoptosis induced by angiotensin II and oxidized LDL (2006) (0)
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- Molecular design of DNA alkylating pyrrole-imidazole polyamides with longer recognition sequence. (2006) (0)
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- Thiophene-Extended Fluorescent Nucleosides as Molecular Rotor-Type Fluorogenic Sensors for Biomolecular Interactions. (2023) (0)
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- Characterization of 2‐Fluoro‐2’‐deoxyadenosine in Duplex, G‐Quadruplex and i‐Motif (2022) (0)
- 1P342 Single molecule FRET measurement of three dimensional G-quadruplex structure of human telomere DNA with Br-modification(New biophysical techniques and instrumentation,Poster Presentations) (2007) (0)
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- Photoreaction of DNA Containing 5‐Halouracil and its Products † (2021) (0)
- Photo‐Cross‐Linking between BrU and Pyrene Residues in an RNA/DNA Hybrid (2022) (0)
- Epigenetic Drug Discovery by Artificial Genetic Switches (2020) (0)
- Chemical and method for analyzing dna sequence by visualizing single-molecule dna and use thereof (2019) (0)
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- Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs (2021) (0)
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- Title RNA-DNA Triplex Formation by Long Noncoding RNAs (2018) (0)
- Identification and characterization of novel enzymes involved in base excision repair for oxidative base damage in DNA (2005) (0)
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- Selective Cleavage of Benzyl Esters and Ethers. (1984) (0)
- OXYMERCURATION-DEMERCURATION OF 6-METHYLENETRICYCLO(3.2.1.0(2,7))OCT-3-EN-8-ONE DERIVATIVES. AN EFFICIENT SYNTHESIS OF 2,4-CYCLOHEXADIENONE DERIVATIVES (1981) (0)
- SLD2 OXIDATIVE STRAND SCISSION OF DNA (1988) (0)
- Folding RNA-Protein Complex into Designed Nanostructures. (2021) (0)
- G-quadruplex Nanostructures Probed at the Single Molecular Level by Force-based Methods (2012) (0)
- Photocontrolled DNA nanotubes as stiffness tunable matrices for controlling cellular behavior. (2023) (0)
- Cover Picture: Chemical Approaches to the Development of Artificial Transcription Factors Based on Pyrrole-Imidazole Polyamides (Chem. Rec. 6/2021) (2021) (0)
- Photoreactivity of 5-iodouracil-containing telomeric DNA. (2003) (0)
- Targeted histone acetylation and gene activation by synthetic molecules that recruit P300 histone acetyltransferase to a specific DNA sequence (2017) (0)
- RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells (2018) (0)
- Nanoparticle-Based Artificial Mitochondrial DNA Transcription Regulator: MitoScript. (2023) (0)
- NMR Spectra of Tropolone Derivatives (1968) (0)
- Catalytic RNA Oligomers Formed by Co-Oligomerization of a Pair of Bimolecular RNase P Ribozymes (2022) (0)
- A Survey of UVA-induced DNA Damage enhanced in the Presence of Drugs (2013) (0)
- Hydrazinolysis of peptidyl resins of phenacyl esteports e supports for solid-phase peptide synthesis. (1975) (0)
- RUNX1–Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors (2022) (0)
- The Biophysical Society of Japan General Incorporated Association NII-Electronic Library Service (2014) (0)
- PHOTOINDUCED REACTIONS. 100. SINGLET-OXYGEN REACTIONS OF 1,4-CYCLOHEXADIENE. . A SYNTHETIC APPROACH TO THE BENZENE 1,4-ENDOPEROXIDE (1978) (0)
- Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome (2018) (0)
- Pure quadrupole resonance of bromine in bromotropolones (1964) (0)
- WITHDRAWN: Evaluation of alkylating pyrrole-imidazole polyamide conjugates by a novel method for high-throughput sequencer. (2017) (0)
- Single-Molecule Visualization of B-Z Transition in DNA Origami Using High-Speed AFM. (2023) (0)
- STRUCTURAL STUDIES OF A STABLE PARALLEL-STRANDED DNA DUPLEX INCORPORATING ISOGUANINE:CYTOSINE AND ISOCYTOSINE:GUANINE BASE PAIRS BY NMR, MINIMIZED AVERAGE STRUCTURE (1998) (0)
- Designing Biomimicking Synthetic Transcription Factors for Therapeutic Gene Modulation (2021) (0)
- Photoreaction of 5'-halouracil-containing DNA. A novel photoproduct at 5'BrU-pyrimidine-3' sequence. (1995) (0)
- Molecular design of hairpin imidazole-pyrrole polyamide for effective DNA alkylation. (2001) (0)
- Abstract 1530: RUNX1 positively regulates ErbB2/HER2 signaling pathway through modulating the expression of SOS1 in gastric cancer cells (2017) (0)
- Selective targeting of mitochondrial DNA by a synthetic DNA-Binding molecule (2016) (0)
- Title A synthetic DNA-binding inhibitor of SOX 2 guides humaninduced pluripotent stem cells to differentiate into mesoderm (2019) (0)
- Title Sequence-specific DNA alkylation by tandem Py-Im (2016) (0)
- 5-Formyluracil, a Major Product of Thymine Oxidation, Induces Base Substitutions and Deletions on a Plasmid Replicated in Escherichia coli (1999) (0)
- Evaluation by Experimentation and Simulation of a FRET Pair Comprising Fluorescent Nucleobase Analogs in Nucleosomes. (2023) (0)
- Corrigendum to "Chlorambucil-conjugated PI-polyamide (Chb-M'), a transcription inhibitor of the RUNX family, has anti-tumor activity against SHH-type medulloblastoma with p53 mutation" [Biochem. Biophys. Res. Commun. 620 (10 September 2022) 150-157]. (2023) (0)
- Nature‐Inspired Design of Smart Biomaterials Using the Chemical Biology of Nucleic Acids (2016) (0)
- 7-azo compounds of 1-acylamino-8-naphthol-3,6-disulfonic acids and salts thereof, processes for their preparation and their use as reactive dyes (1969) (0)
- Human Telomeric DNA mixed-parallel/antiparallel quadruplex under Physiological Ionic Conditions Stabilized by Proper Incorporation of 8-Bromoguanosines (2007) (0)
- Synthesis of 2-Deoxy-2-fluoro-D-galactopyranose: Reaction of D-Galactal with Acetyl Hypofluorite (1984) (0)
- Title Examining cooperative binding of Sox 2 on DC 5 regulatory element upon complex formation with Pax 6 through excess electron transfer assay (2019) (0)
- Title Translation-dependent unwinding of stem ‒ loops by UPF 1 licenses Regnase-1 to degrade inflammatory mRNAs (2019) (0)
- Cleavage of parallel-stranded DNA duplex by peplomycin metal complexes. (1999) (0)
- 1PS042 Multiple kinesin molecules coordinate to ensure the long-distance walking : a DNA-kinesin hybrid nanomachine study(The 50th Annual Meeting of the Biophysical Society of Japan) (2012) (0)
- Single-molecule Analysis Using DNA Origami Nanostructures (2013) (0)
- Direct Observation and Analysis of the Dynamics of the Photoresponsive Transcription Factor GAL4 (2019) (0)
- DNA strand scission by antitumor antibiotics. Detection of C-4'-hydroxylated abasic sites in DNA. (1989) (0)
- Single-Molecule Observation in the DNA Origami Nanostructures (2014) (0)
- Towards artificial repair of UV-damaged DNA: studies on drug binding and alkali hydrolysis. (2003) (0)
- The Solvomercuration, Bromination, and Related Reactions of 1,5-Dimethyl-6-methylenetricyclo[3.2.1.O2,7]oct-3-en-8-one and Its Related Compounds. (1982) (0)
- Title Paradoxical enhancement of leukemogenesis in acute myeloidleukemia with moderately attenuated RUNX 1 expressions (2019) (0)
- Direct observation of G-quadruplexes using DNA origami nanoscaffold (2015) (0)
- Title Direct analysis of Holliday junction resolving enzyme in aDNA origami nanostructure (2019) (0)
- PHOTOINDUCED REACTIONS. 113. PHOTOCHEMICAL REACTION OF 8-AZAXANTHINE WITH NUCLEOPHILES (1980) (0)
- Title Targeted Suppression of EVI1 Oncogene Expression by Sequence-Specific Pyrrole-Imidazole Polyamide. Author(s) (2022) (0)
- DNA cleavage reaction by photochemically modified bleomycin. (1986) (0)
- RNA nano-structures based on a closed ribozyme trimer as triangular unit modules (2017) (0)
- Development of transcriptional silencer pyrrole-imidazole polyamides targeting TGF-β1 gene based on the chemical genomics (2017) (0)
- Title A synthetic small molecule for rapid induction of multiplepluripotency genes in mouse embryonic fibroblasts (2017) (0)
- Progress and Prospects of Pyrrole‐Imidazole Polyamide—Fluorophore Conjugates as Sequence‐Selective DNA Probes (2013) (0)
- Title Mechanical properties of DNA origami nanoassemblies aredetermined by Holliday junction mechanophores (2019) (0)
- Molecular Design of Effective Sequence-specific DNA Alkylating Agents using Pyrrole-Imidazole Polyamides (2003) (0)
- Abstract 3357: Genetic regulation of RUNX2 induce apoptotic cell death through regulating the expression of SOX2 in CRPC-NE cells (2018) (0)
- Molecular design of alkylating pyrrole-imidazole polyamides with indole linker. (2004) (0)
- Rational design of orthogonal gene transcription nano device on DNA origami (2017) (0)
- Oxidative strand scission of DNA (1989) (0)
- Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation. (2021) (0)
- GGC repeat expansion in NOTCH2NLC is the cause of both sporadic and familial neuronal intranuclear inclusion disease (2019) (0)
- Verticality perception and lateral trunk flexion in Parkinson’s disease (2017) (0)
- New loop polyamide (2003) (0)
- Purification and Characterization of Ciona intestinalis Nth Homologue (2005) (0)
- DNA Origami‐Based Construction of Meso‐Scale Multi‐Dimensional Architects and Expression of the Functionality in the Designed DNA Nanospace (2012) (0)
- Development of a screening method for a physiologically active pyrrole-imidazole derivative (2000) (0)
- Chemical Synthesis of 2-Deoxy-2-[18F]Fluoroacetamido-4-O-(2-amino-2-deoxy-β-D-glucopyranosyl)-D-glucopyranose from [18F]Fluoride (1990) (0)
- Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo‐controlled pilot trial (2018) (0)
- Photochemical deoxyribose C2' oxidation in 5-iodouracil-containing hexanucleotide. (1992) (0)
- DNA Strand Scission by Bleomycin: Catalytic Cleavage and Strand Selectivity. (1986) (0)
- Angkorian Khmer stoneware: production and provenance (2021) (0)
- Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease (2019) (0)
- The synthesis of pyrrole(Py)/imidazole(Im) polyamide CPI conjugates which possess DNA interstrand cross-linking activity. (2000) (0)
- The Eye Response Test Alone Is Sufficient To Predict Stroke Outcome: Re-Introduction of Japan Coma Scale (P01.223) (2013) (0)
- Directed Differentiation Of Stem Cells Using DNA-binding Py-Im Polyamides (2016) (0)
- Title Distinct DNA-based epigenetic switches trigger transcriptionalactivation of silent genes in human dermal fibroblasts (2017) (0)
- Photochemical Cycloaditions of Benzophenone with Rigid Dicyclopropylethylenes--Substituent Effect on the Rearrangement of Radicals Having Tetracyclo〔3.3.0.0.2,804,6〕 octan Skeleton (1983) (0)
- Abstract 3533: DNA binding molecules as a new tool to regulate cancer cell fate (2011) (0)
- Reinvestigation of the structure of the pyrene-1-carboxylic acid-heptakis(2,6-di-O-methyl)cyclomaltoheptaose complex in water (1993) (0)
- A Facile One-pot Synthesis of N-[18F]Fluoroacetyl-D-mannosamine (1989) (0)
- Systemic cellular immunity and neuroinflammation during acute flare-up in multiple sclerosis and neuromyelitis optica spectrum disorder patients (2021) (0)
- [Metabolisms of cyanide in amyotrophic lateral sclerosis (author's transl)]. (1982) (0)
- PHOTOREACTION OF THYMIDINE IN THE PRESENCE OF LYSINE. PHOTOCHEMISTRY OF NUCLEIC ACID BASE (1981) (0)
- Title Triggering nucleic acid nanostructure assembly by conditionalkissing interactions (2018) (0)
- 8-Methylguanine-containing oligonucleotides: useful structural constraint for Z form DNA. (1995) (0)
- Title Baseline Plasma C-Reactive Protein Concentrations and MotorPrognosis in Parkinson Disease (2019) (0)
- A hypothesis concerning disturbed axoplasmic flow as a common pathogenic mechanism linking amyloidogenesis and tangle formation of Alzheimer's disease. (1993) (0)
- Excited-State Behavior of Tryptamine (I) and Related Indoles (II). Remarkably Efficient Intramolecular Proton-Induced Quenching. (1988) (0)
- CARBON-13 NUCLEAR MAGNETIC RESONANCE SPECTRA OF GAMMA-RIBONUCLEOSIDES (1974) (0)
- Sequence-Specific Control of Mitochondrial Gene Transcription Using Programmable Synthetic Gene Switches Called MITO-PIPs. (2021) (0)
- Telomeric quadruplexes as therapeutic targets (2020) (0)
- Abstract 2937: The regulation of FGFR signaling by RTK adaptor protein down-regulation through CROX (cluster regulation of RUNX) theory in DNPC (2020) (0)
- Title Telomere Visualization in Tissue Sections usingPyrrole ‒ Imidazole Polyamide Probes (2016) (0)
- Pyrrole‐Imidazole Polyamides – A Frontrunner in Nucleic Acid‐Based Small Molecule Drugs (2023) (0)
- Chemistry of Nucleoside-Amino Acid Adducts and Its Relevance to Photoinduced Lesions (1984) (0)
- Synthesis and evaluation of sequence-specific DNA alkylating agents: effect of alkylation subunits. (2006) (0)
- Examination of somatic cell reprogramming using PI polyamides (2016) (0)
- Single-Molecule Analysis Using DNA Origami (2012) (0)
- DNA-Based Daisy Chain Rotaxane Nanocomposite Hydrogels as Dual-Programmable Dynamic Scaffolds for Stem Cell Adhesion. (2022) (0)
- Analysis of distamycin A binding to UV-damaged DNA. (2004) (0)
- Detection of photoinduced electron transfer from Sso7d to DNA. (2006) (0)
- ELECTROORGANIC CHEMISTRY. PART 49. ELECTROREDUCTIVE HYDROCOUPLING OF ACTIVATED OLEFINS WITH KETONES OR ALDEHYDES IN THE PRESENCE OF TRIMETHYLCHLOROSILANE (1981) (0)
- Dynamic Stabilization of DNA Assembly by Using Pyrrole‐Imidazole Polyamide (2020) (0)
- Twelve Colors of Streptavidin-Fluorescent Proteins (SA-FPs): A Versatile Tool to Visualize Genetic Information in Single-Molecule DNA. (2022) (0)
- The Effect of 5-Formyluracil, a Major Oxidative Lesion of Thymine, on Biological Function of DNA in vivo and in vitro (1998) (0)
- Orientation preferences of hairpin pyrrole-imidazole polyamides toward mCGG site. (2019) (0)
- Purification and Characterization of 5-Formyluracil DNA Glycosylase from Human Cells in Culture (1999) (0)
- The Effect of 5-Formyluracil and 5-Hydroxymethyluracil, a Major Oxidative Lesion of Thymine, on Biological Functions of DNA (1997) (0)
- INTERACTIONS OF DEGLYCOSYLATED COBALT(III)-PEPLEOMYCIN WITH DNA, NMR, MINIMIZED AVERAGE STRUCTURE (1997) (0)
- Targeting Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia with a Novel Transcriptional Inhibitor (2016) (0)
- Non‐invasive Regulation of Cellular Morphology Using a Photoswitchable Mechanical DNA Polymer (2021) (0)
- 2P-112 Examination of G-quadruplex Structures of Human Telomere DNA Based on the Single Molecule FRET Measurements with BrG-substitutions(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
- Purification and Characterization of Schizosaccharomyces pombe Nth Homologue (2002) (0)
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What Schools Are Affiliated With Hiroshi Sugiyama?
Hiroshi Sugiyama is affiliated with the following schools:
