Hiroshi Ueda

Q: What Schools Are Affiliated With Hiroshi Ueda

Hiroshi Ueda is affiliated with the following schools: Teikyo University, University of Tokyo, Nagasaki University, Osaka University of Pharmaceutical Sciences, Institute of Science Tokyo, Gifu University, Yokohama City University, Kyoto University

Hiroshi Ueda's AcademicInfluence.com Rankings

Hiroshi Ueda

Computer Science

#7208

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#7589

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Machine Learning

#2592

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#2627

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Artificial Intelligence

#2884

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#2929

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Database

#4270

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#4441

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computer-science Degrees

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Computer Science

Hiroshi Ueda's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Hiroshi Ueda's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling (2004) (285)
Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens. (2002) (282)
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade (2009) (260)
A novel analgesic dipeptide from bovine brain is a possible Met-enkephalin releaser (1979) (236)
Molecular mechanisms of neuropathic pain-phenotypic switch and initiation mechanisms. (2006) (231)
Epigenetic Gene Silencing Underlies C-Fiber Dysfunctions in Neuropathic Pain (2010) (171)
Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. (1979) (156)
Partial loss of tolerance liability to morphine analgesia in mice lacking the nociceptin receptor gene (1997) (136)
Novel Expression of Vanilloid Receptor 1 on Capsaicin-Insensitive Fibers Accounts for the Analgesic Effect of Capsaicin Cream in Neuropathic Pain (2003) (133)
Inhibition of Paclitaxel-Induced A-Fiber Hypersensitization by Gabapentin (2006) (130)
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception. (1999) (127)
Enhanced Spinal Nociceptin Receptor Expression Develops Morphine Tolerance and Dependence (2000) (124)
Loss of Peripheral Morphine Analgesia Contributes to the Reduced Effectiveness of Systemic Morphine in Neuropathic Pain (2004) (121)
Peripheral mechanisms of neuropathic pain – involvement of lysophosphatidic acid receptor-mediated demyelination (2008) (120)
NEUROBIOLOGY OF l-DOPAergic SYSTEMS (1996) (119)
Low doses of naloxone produce analgesia in the mouse brain by blocking presynaptic autoinhibition of enkephalin release (1986) (119)
Comparison of the analgesic effects of various opioid peptides by a newly devised intracisternal injection technique in conscious mice. (1979) (118)
Increased Expression of Vanilloid Receptor 1 on Myelinated Primary Afferent Neurons Contributes to the Antihyperalgesic Effect of Capsaicin Cream in Diabetic Neuropathic Pain in Mice (2003) (116)
A Hydroxyl Group of Flavonoids Affects Oral Anti-inflammatory Activity and Inhibition of Systemic Tumor Necrosis Factor-α Production (2004) (115)
Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction. (2000) (115)
Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice. (1998) (110)
Locus-Specific Rescue of GluRϵ1 NMDA Receptors in Mutant Mice Identifies the Brain Regions Important for Morphine Tolerance and Dependence (2003) (108)
Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain (2008) (106)
Aripiprazole, a novel antipsychotic drug, inhibits quinpirole-evoked GTPase activity but does not up-regulate dopamine D2 receptor following repeated treatment in the rat striatum. (1997) (105)
Mechanisms underlying morphine analgesic tolerance and dependence. (2009) (103)
Inhibitory effect of Perilla leaf extract and luteolin on mouse skin tumor promotion. (2003) (99)
Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid (2008) (99)
TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function. (2010) (98)
Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord. (1999) (97)
Morphine-Induced Chemotaxis and Brain-Derived Neurotrophic Factor Expression in Microglia (2005) (91)
Lysophosphatidic acid: chemical signature of neuropathic pain. (2013) (90)
Prolonged gabapentin analgesia in an experimental mouse model of fibromyalgia (2008) (89)
Reconstitution of rat brain mu opioid receptors with purified guanine nucleotide-binding regulatory proteins, Gi and Go. (1988) (85)
Switching of Bradykinin-Mediated Nociception Following Partial Sciatic Nerve Injury in Mice (2004) (85)
Neuron-restrictive silencer factor causes epigenetic silencing of Kv4.3 gene after peripheral nerve injury (2010) (81)
Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism (2002) (81)
Protein kinase C involvement in homologous desensitization of delta- opioid receptor coupled to Gi1-phospholipase C activation in Xenopus oocytes (1995) (79)
The kyotorphin (tyrosine-arginine) receptor and a selective reconstitution with purified Gi, measured with GTPase and phospholipase C assays. (1989) (78)
Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine (2010) (76)
Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain (2010) (75)
Lysophosphatidic acid‐induced membrane ruffling and brain‐derived neurotrophic factor gene expression are mediated by ATP release in primary microglia (2008) (74)
Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception (2002) (74)
X-ray crystallographic conformational study of 5'-O-[N-(L-alanyl)-sulfamoyl]adenosine, a substrate analogue for alanyl-tRNA synthetase. (1991) (73)
Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain (2009) (71)
LPA-mediated demyelination in ex vivo culture of dorsal root (2007) (70)
Regional distribution of a novel analgesic dipeptide kyotorphin (Tyr-Arg) in the rat brain and spinal cord (1980) (68)
Protein Kinase C-Mediated Inhibition of μ-Opioid Receptor Internalization and Its Involvement in the Development of Acute Tolerance to Peripheral μ-Agonist Analgesia (2001) (68)
Epigenetic regulation of BDNF expression in the primary sensory neurons after peripheral nerve injury: Implications in the development of neuropathic pain (2013) (68)
Necessity of lysophosphatidic acid receptor 1 for development of arthritis. (2013) (67)
Identification of prothymosin-α1, the necrosis–apoptosis switch molecule in cortical neuronal cultures (2007) (65)
Pain and the bulbospinal noradrenergic system: pain-induced increase in normetanephrine content in the spinal cord and its modification by morphine. (1979) (64)
Microglial activation mediates de novo lysophosphatidic acid production in a model of neuropathic pain (2010) (64)
Mechanism of kyotorphin-induced release of Met-enkephalin from guinea pig striatum and spinal cord (1981) (63)
Metabotropic Neurosteroid/ς-Receptor Involved in Stimulation of Nociceptor Endings of Mice (2001) (63)
Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice (1999) (62)
Presynaptic mediation by α2-, β1- and β2-adrenoceptors of endogenous noradrenaline and dopamine release from slices of rat hypothalamus (1983) (60)
Cell death mode switch from necrosis to apoptosis in brain. (2004) (59)
Nociceptin‐induced scratching, biting and licking in mice: involvement of spinal NK1 receptors (1999) (59)
HDAC inhibitors restore C‐fibre sensitivity in experimental neuropathic pain model (2013) (59)
Functional Reconstitution of Purified Gi and Go with μ‐Opioid Receptors in Guinea Pig Striatal Membranes Pretreated with Micromolar Concentrations of N‐Ethylmaleimide (1990) (56)
δ Opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes (1993) (56)
An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model (2013) (55)
A selective agonist of endothelin type B receptor, IRL 1620, stimulates cyclic GMP increase via nitric oxide formation in rat aorta. (1993) (54)
Protein kinase C-mediated acute tolerance to peripheral mu-opioid analgesia in the bradykinin-nociception test in mice. (2000) (53)
Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission. (2000) (52)
Evidence for lysophosphatidic acid 1 receptor signaling in the early phase of neuropathic pain mechanisms in experiments using Ki‐16425, a lysophosphatidic acid 1 receptor antagonist (2009) (51)
Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice (2014) (49)
Phosphorylated μ-opioid receptor purified from rat brains lacks functional coupling with Gi1, a GTP-binding protein in reconstituted lipid vesicles (1990) (49)
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX‐mediated conversion to LPA, an initiator of neuropathic pain (2008) (49)
Retinal cell type‐specific prevention of ischemia‐induced damages by LPS‐TLR4 signaling through microglia (2013) (48)
Non-effective dose of exogenously applied l-DOPA itself stereoselectively potentiates postsynaptic D2 receptor-mediated locomotor activities of conscious rats (1994) (47)
Isolation and identification of an analgesic opioid dipeptide kyotorphin (TYR-ARG) from bovine brain (1981) (47)
Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice (2006) (47)
In vivo molecular signal transduction of peripheral mechanisms of pain. (1999) (47)
Pharmacological switch in Aβ-fiber stimulation-induced spinal transmission in mice with partial sciatic nerve injury (2008) (46)
Neurosteroids stimulate G protein-coupled sigma receptors in mouse brain synaptic membrane (2001) (45)
Endocrine disrupting chemical atrazine causes degranulation through Gq/11 protein-coupled neurosteroid receptor in mast cells. (2006) (44)
New approaches to study the development of morphine tolerance and dependence. (2003) (43)
Metabotropic neurosteroid/sigma-receptor involved in stimulation of nociceptor endings of mice. (2001) (42)
Curcumin blocks chronic morphine analgesic tolerance and brain-derived neurotrophic factor upregulation (2009) (41)
Involvement of LPA1 receptor signaling in the reorganization of spinal input through Abeta-fibers in mice with partial sciatic nerve injury (2008) (40)
Evidence for the tonic inhibition of spinal pain by nicotinic cholinergic transmission through primary afferents (2007) (40)
In vivo signal transduction of nociceptive response by kyotorphin (tyrosine-arginine) through Galpha(i)- and inositol trisphosphate-mediated Ca(2+) influx. (2000) (40)
Emerging functions for tuberoinfundibular peptide of 39 residues (2003) (40)
Endogenously released l-DOPA itself tonically functions to potentiate postsynaptic D2 receptor-mediated locomotor activities of conscious rats (1994) (40)
Calpain‐mediated down‐regulation of myelin‐associated glycoprotein in lysophosphatidic acid‐induced neuropathic pain (2010) (40)
Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain (2006) (39)
Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine (2000) (39)
Presynaptic inhibitory dopamine receptors on noradrenergic nerve terminals: analysis of biphasic actions of dopamine and apomorphine on the release of endogenous norepinephrine in rat hypothalamic slices. (1985) (39)
Phosphorylation of μ-opioid receptors — a putative mechanism of selective uncoupling of receptor — Gi interaction, measured with low-K m CTPase and nucleotide-sensitive agonist binding (1989) (38)
Characterization of three different sensory fibers by use of neonatal capsaicin treatment, spinal antagonism and a novel electrical stimulation-induced paw flexion test (2006) (38)
A Strategy for Co-former Selection to Design Stable Co-amorphous Formations Based on Physicochemical Properties of Non-steroidal Inflammatory Drugs (2016) (38)
Absence of morphine analgesia and its underlying descending serotonergic activation in an experimental mouse model of fibromyalgia (2010) (37)
Protein kinase C-mediated inhibition of mu-opioid receptor internalization and its involvement in the development of acute tolerance to peripheral mu-agonist analgesia. (2001) (37)
Involvement of epinephrine in the presynaptic beta adrenoceptor mechanism of norepinephrine release from rat hypothalamic slices. (1985) (37)
Insulin Receptor-Protein Kinase C-γ Signaling Mediates Inhibition of Hypoxia-Induced Necrosis of Cortical Neurons (2005) (36)
Raman mapping for kinetic analysis of crystallization of amorphous drug based on distributional images. (2014) (36)
Involvement of LPA1 receptor signaling in cerebral ischemia-induced neuropathic pain (2013) (36)
Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants (2011) (35)
Characterization of nociceptin-stimulated in situ [35S]GTPγS binding in comparison with opioid agonist-stimulated ones in brain regions of the mice (1997) (34)
Prothymosin alpha and cell death mode switch, a novel target for the prevention of cerebral ischemia-induced damage. (2009) (34)
Lack of tolerance in peripheral opioid analgesia in mice. (1998) (34)
Tonic inhibitory role of alpha4beta2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice. (2006) (34)
Locus‐Specific Involvement of Anti‐Opioid Systems in Morphine Tolerance and Dependence (2004) (34)
Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling (2015) (34)
Opioid μ- and κ-receptor mediate phospholipase C activation through Gi1 in Xenopus oocytes (1995) (33)
Lysophosphatidic acid signaling is the definitive mechanism underlying neuropathic pain. (2017) (33)
Cell Density-Dependent Death Mode Switch of Cultured Cortical Neurons Under Serum-Free Starvation Stress (2001) (33)
l-DOPA inhibits spontaneous acetylcholine release from the striatum of experimental Parkinson's model rats (1995) (33)
Degradation of kyotorphin by a purified membrane-bound-aminopeptidase from monkey brain: potentiation of kyotorphin-induced analgesia by a highly effective inhibitor, bestatin. (1985) (33)
Minocycline Does Not Decrease Intensity of Neuropathic Pain Intensity, But Does Improve Its Affective Dimension (2015) (33)
Prothymosin‐alpha preconditioning activates TLR4–TRIF signaling to induce protection of ischemic retina (2015) (32)
In Vivo Pain-Inhibitory Role of Nociceptin/Orphanin FQ in Spinal Cord (2003) (31)
Inositol 1,4,5-Trisphosphate-Gated Calcium Transport through Plasma Membranes in Nerve Terminals (1996) (31)
Nonopioid and Neuropathy-Specific Analgesic Action of the Nootropic Drug Nefiracetam in Mice (2002) (31)
Lysophosphatidic acid LPA1 and LPA3 receptors play roles in the maintenance of late tissue plasminogen activator-induced central poststroke pain in mice (2018) (31)
Downregulation of P2X3 receptor‐dependent sensory functions in A/J inbred mouse strain (2002) (30)
Activation of Gi1 by lysophosphatidic acid receptor without ligand in the baculovirus expression system. (1999) (30)
Microglia activation precedes the anti-opioid BDNF and NMDA receptor mechanisms underlying morphine analgesic tolerance. (2014) (29)
Involvement of lysophosphatidic acid–induced astrocyte activation underlying the maintenance of partial sciatic nerve injury–induced neuropathic pain (2018) (29)
Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain (2011) (29)
Profiling of BoNT/C3-reversible gene expression induced by lysophosphatidic acid: ephrinB1 gene up-regulation underlying neuropathic hyperalgesia and allodynia (2009) (29)
The effect of polysorbate 80 on brain uptake and analgesic effect of D-kyotorphin (1989) (29)
Possible mechanisms by which adipocyte lipolysis is enhanced in exercise-trained rats. (2002) (29)
Analgesic dipeptide, kyotorphin (Tyr-Arg), is highly concentrated in the synaptosomal fraction of the rat brain (1982) (28)
Altered tonic L-3,4-dihydroxyphenylalanine systems in the nucleus tractus solitarii and the rostral ventrolateral medulla of spontaneously hypertensive rats (1995) (28)
Evidence for serum-deprivation-induced co-release of FGF-1 and S100A13 from astrocytes (2006) (28)
[Lysophosphatidic acid as initiator of neuropathic pain]. (2011) (28)
Prothymosin α plays multifunctional cell robustness roles in genomic, epigenetic, and nongenomic mechanisms (2012) (27)
Neuronal Necrosis Inhibition by Insulin through Protein Kinase C Activation (2003) (27)
6-OHDA-induced lesion of the nigrostriatal dopaminergic neurons potentiates the inhibitory effect of 7-OHDPAT, a selective D3 agonist, on acetylcholine release during striatal microdialysis in conscious rats (1994) (27)
Expression of a synthetic gene for human cap binding protein (human IF-4E) in Escherichia coli and fluorescence studies on interaction with mRNA cap structure analogues. (1991) (27)
Peripheral non-opioid analgesic effects of kyotorphin in mice (1997) (27)
NSAID zaltoprofen possesses novel anti-nociceptive mechanism through blockage of B2-type bradykinin receptor in nerve endings (2006) (26)
Multiple pathways of angiotensin I conversion and their functional role in the canine penile corpus cavernosum. (2001) (26)
κ-Opioid agonist inhibits phospholipase C, possibly via an inhibition of G-protein activity (1990) (26)
Novel type of Gq/11 protein‐coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL‐2H3) (2005) (25)
Epigenetic modification in neuropathic pain. (2014) (25)
Sigma ligands stimulate GTPase activity in mouse prefrontal membranes: evidence for the existence of metabotropic sigma receptor (1997) (25)
Presynaptic α 2- and dopamine-receptor-mediated inhibitory mechanisms and dopamine nerve terminals in the rat hypothalamus (1983) (24)
LPA1 receptor involvement in fibromyalgia-like pain induced by intermittent psychological stress, empathy (2017) (24)
Histone deacetylase inhibitors relieve morphine resistance in neuropathic pain after peripheral nerve injury. (2015) (23)
A subtype of opioid κ‐receptor is coupled to inhibition of Gil‐mediated phospholipase C activity in the guinea pig cerebellum (1995) (23)
Supersensitization of intrastriatal dopamine receptors involved in opposite regulation of acetylcholine release in Parkinson's model rats (1994) (23)
Neurosteroid-induced hyperalgesia through a histamine release is inhibited by progesterone and p,p′-DDE, an endocrine disrupting chemical (2003) (22)
Peripheral morphine analgesia resistant to tolerance in chronic morphine-treated mice (1999) (22)
Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor Activation (2015) (21)
The specific opioid κ-agonist U-50,488H inhibits low Km GTPase (1987) (21)
Pertussis toxin (IAP) enhances maitotoxin (a putative Ca2+ channel agonist)-induced Ca2+ entry into synaptosomes. (1986) (21)
Evidence for receptor‐mediated inhibition of intrinsic activity of GTP‐binding protein, Gi1 and Gi2, but not G0 in reconstitution experiments (1990) (21)
NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice (2015) (21)
Presynaptic opioid κ-receptor and regulation of the release of Met-enkephalin in the rat brainstem (1987) (21)
Purified opioid μ-receptor is of a different molecular size than δ- and κ-receptors (1987) (21)
Excess release of substance P from the spinal cord of mice during morphine withdrawal and involvement of the enhancement of presynaptic Ca2+ entry (1987) (21)
Selective coupling of mouse brain metabotropic sigma (σ) receptor with recombinant Gi1 (1999) (20)
Circadian-Dependent Learning and Memory Enhancement in Nociceptin Receptor-Deficient Mice with a Novel KUROBOX Apparatus Using Stress-Free Positive Cue Task (2007) (20)
Cooperative stacking and hydrogen bond pairing interactions of fragment peptide in cap binding protein with mRNA cap structure. (1991) (20)
Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats. (2004) (20)
Single application of A2 NTX, a botulinum toxin A2 subunit, prevents chronic pain over long periods in both diabetic and spinal cord injury-induced neuropathic pain models. (2012) (20)
Molecular mechanism of neuropathic pain. (2003) (20)
LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model. (2018) (20)
Prothymosin α as robustness molecule against ischemic stress to brain and retina (2010) (19)
Interleukin-1β Plays Key Roles in LPA-Induced Amplification of LPA Production in Neuropathic Pain Model (2013) (19)
Novel neuroprotective action of prothymosin alpha‐derived peptide against retinal and brain ischemic damages (2013) (19)
Role of β-adrenoceptors in the expression of morphine withdrawal signs (1994) (19)
A possible recognition mode of mRNA cap terminal structure by peptide: cooperative stacking and hydrogen-bond pairing interactions between m7GpppA and Trp-Leu-Glu. (1988) (19)
Stimulation of peripheral nociceptor endings by low dose morphine and its signaling mechanism (2002) (19)
The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals (2003) (19)
Nocistatin and Prepro-Nociceptin/Orphanin FQ 160–187 Cause Nociception through Activation of Gi/o in Capsaicin-Sensitive and of Gs in Capsaicin-Insensitive Nociceptors, Respectively (2003) (18)
Parallel Stimulations of in Vitro and in Situ [35S]GTPγS Binding by Endomorphin 1 and DAMGO in Mouse Brains (1998) (18)
Voltage-Dependent N-Type Ca2+ Channel Activity Regulates the Interaction Between FGF-1 and S100A13 for Stress-Induced Non-Vesicular Release (2006) (18)
Myelin-related gene silencing mediated by LPA1 - Rho/ROCK signaling is correlated to acetylation of NFκB in S16 Schwann cells. (2016) (18)
Anomalous role change of tertiary amino and ester groups as hydrogen acceptors in eudragit E based solid dispersion depending on the concentration of naproxen. (2015) (18)
Relationship between acid strength distributions of silica alumina catalysts and their activities (1986) (17)
Protein kinase inhibitor potentiates opioid δ-receptor currents in Xenopus oocytes. (1994) (17)
A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models. (2017) (17)
Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke (2008) (17)
Alteration in serum neural cell adhesion molecule in patients of schizophrenia (2007) (17)
Enhanced expression of neuronal nitric oxide synthase in islets of exercise-trained rats. (2003) (17)
Adamantyl amino acid as γ-turn inducer for peptide (1997) (17)
Inhibition of tumor necrosis factor-alpha production by orally administering a perilla leaf extract. (1997) (16)
(−)1-(Benzofuran-2-yl)-2-propylaminopentane Shows Survival Effect on Cortical Neurons Under Serum-Free Condition Through Sigma Receptors (2000) (16)
Species and age-dependent differences of functional coupling between opioid δ-receptor and G-proteins and possible involvement of protein kinase C in striatal membranes (1994) (16)
Adrenaline involvement in the presynaptic beta-adrenoceptor-mediated mechanism of dopamine release from slices of the rat hypothalamus. (1984) (16)
The presence of Ca(2+)-independent phospholipase A1 highly specific for phosphatidylinositol in bovine brain. (1993) (16)
Neuroprotective DAMPs member prothymosin alpha has additional beneficial actions against cerebral ischemia-induced vascular damages. (2016) (16)
Binding of [35S]GTPgammaS stimulated by (+)-pentazocine sigma receptor agonist, is abundant in the guinea pig spleen. (2000) (16)
Donepezil Reverses Intermittent Stress-Induced Generalized Chronic Pain Syndrome in Mice (2015) (16)
Subconvulsive doses of intracisternal bicuculline methiodide, a GABAA receptor antagonist, produce potent analgesia as measured in the tail pinch test in mice. (1987) (16)
Uptake and release of kyotorphin in rat brain synaptosomes. (1986) (16)
Morphine-induced overexpression of prepro-nociceptin/orphanin FQ in cultured astrocytes (2005) (15)
Exercise training increases membrane bound form of tumor necrosis factor-alpha receptors with decreases in the secretion of soluble forms of receptors in rat adipocytes. (2002) (15)
Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice. (2001) (15)
Subcellular dissemination of prothymosin alpha at normal physiology: immunohistochemical vis-a-vis western blotting perspective (2016) (15)
Amlexanox Inhibits Cerebral Ischemia-Induced Delayed Astrocytic High-Mobility Group Box 1 Release and Subsequent Brain Damage (2018) (15)
LPA receptor signaling as a therapeutic target for radical treatment of neuropathic pain and fibromyalgia. (2019) (15)
Endocrine disrupting chemicals bind to a novel receptor, microtubule‐associated protein 2, and positively and negatively regulate dendritic outgrowth in hippocampal neurons (2010) (15)
Critical Functionality Effects from Storage Temperature on Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Suspensions (2019) (15)
Neuroprotective impact of prothymosin alpha-derived hexapeptide against retinal ischemia–reperfusion (2016) (14)
Parathyroid hormone 2 receptor is a functional marker of nociceptive myelinated fibers responsible for neuropathic pain (2010) (14)
Anti-opioid systems in morphine tolerance and addiction--locus-specific involvement of nociceptin and the NMDA receptor. (2004) (14)
Pre‐emptive morphine treatment abolishes nerve injury‐induced lysophospholipid synthesis in mass spectrometrical analysis (2011) (14)
Studies on peptides. XCIV. Synthesis and activity of kyotorphin and its analogs. (1980) (14)
Non-opioid analgesia of the neuropeptide, neo-kyotorphin and possible mediation by inhibition of GABA release in the mouse brain (1987) (14)
Neuron‐specific non‐classical release of prothymosin alpha: a novel neuroprotective damage‐associated molecular patterns (2012) (14)
The maitotoxin-evoked Ca2+ entry into synaptosomes is enhanced by cholera toxin (1986) (13)
A Novel Method for the Synthesis of Kyotorphin, Tyr-Arg, and 3H-Tyr-Arg, Catalyzed by Tyrosyl-tRNA Synthetase from Bacillus stearothermophilus (1987) (13)
Supersensitization of neurochemical responses by L-DOPA and dopamine receptor agonists in the striatum of experimental Parkinson's disease model rats. (1995) (13)
Molecular dynamics study-based mechanism of nefiracetam-induced NMDA receptor potentiation (2015) (13)
Involvement of angiotensin II receptor subtypes during testicular development in rats. (1998) (13)
Synergistic Ca2+ and Cu2+ requirements of the FGF1–S100A13 interaction measured by quartz crystal microbalance: An initial step in amlexanox-reversible non-classical release of FGF1 (2008) (13)
The Cognition-Enhancer Nefiracetam Inhibits Both Necrosis and Apoptosis in Retinal Ischemic Models in Vitro and in Vivo (2004) (13)
Neurobiology of the Edg2 lysophosphatidic acid receptor. (2001) (13)
Age‐dependent dystonia in striatal Gγ7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole (2013) (13)
Regulation of an Opioid Receptor Chaperone Protein, RTP4, by Morphine (2018) (13)
Gi1 and GoA differentially determine kinetic efficacies of agonists for κ‐opioid receptor (2000) (13)
P-glycoprotein inhibitors improve effective dose and time of pregabalin to inhibit intermittent cold stress-induced central pain. (2016) (13)
Prothymosin alpha‐deficiency enhances anxiety‐like behaviors and impairs learning/memory functions and neurogenesis (2017) (13)
Evidence for a metabostatic opioid ϰ‐receptor inhibiting pertussis toxin‐sensitive metabotropic glutamate receptor‐currents in Xenopus oocytes (1995) (12)
How is kyotorphin (Tyr-Arg) generated in the brain? (1985) (12)
Supersensitivity of quinpirole-evoked GTPase activation without changes in gene expression of D2 and Gi protein in the striatum of hemi-dopaminergic lesioned rats (1994) (12)
Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis (2019) (11)
Association Between Polymorphisms in the Purinergic P2Y12 Receptor Gene and Severity of Both Cancer Pain and Postoperative Pain (2018) (11)
Low dose of kyotorphin (tyrosine-arginine) induces nociceptive responses through a substance P release from nociceptor endings. (1999) (11)
Lysophosphatidic acid as an initiator of neuropathic pain: biosynthesis and demyelination (2011) (11)
Signaling of lysophosphatidic acid-evoked chloride current: calcium release from inositol trisphosphate-sensitive store. (1998) (11)
Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice (2005) (10)
A Subtype of κ‐Opioid Receptor Mediates Inhibition of High‐Affinity GTPase Inherent in Gi1 in Guinea Pig Cerebellar Membranes (1996) (10)
Pituitary-dependent expression of the testicular angiotensin II receptor and its subtypes in rats. (1998) (10)
Induction of tumor necrosis factor in a murine tumor by systemic administration of a novel synthetic lipid A analogue, ONO-4007. (1997) (10)
Systems Pathology of Neuropathic Pain and Fibromyalgia. (2019) (10)
Regional Distribution and Cell Type-Specific Subcellular Localization of Prothymosin Alpha in Brain (2011) (10)
Pathogenic mechanisms of lipid mediator lysophosphatidic acid in chronic pain. (2020) (10)
Hydrolytic deactivation of kyotorphin by the rodent brain homogenates and sera. (1984) (10)
An enzymatically stable kyotorphin analog induces pain in subattomol doses☆ (2000) (10)
New synthesis of thiiranes by fluoride ion-promoted reaction of S-methyl-S′-trimethylsilylmethyl N-(p-toluenesulfonyl)dithioiminocarbonate and 2-(trimethylsilylmethylthio)thiazoline with aldehydes☆ (1992) (9)
Diminished α 2-adrenoceptor-mediated modulation of noradrenergic neurotransmission in the posterior hypothalamus of spontaneously hypertensive rats (1986) (9)
NR2A-NMDA Receptor Blockade Reverses the Lack of Morphine Analgesia Without Affecting Chronic Pain Status in a Fibromyalgia-Like Mouse Model (2020) (9)
The cognition-enhancer nefiracetam is protective in BDNF-independent neuronal cell death under the serum-free condition (2002) (9)
Induction of tumor necrosis factor-alpha in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide. (2001) (9)
Therapeutic benefits of 9-amino acid peptide derived from prothymosin alpha against ischemic damages (2013) (9)
Multiple opioid receptors and GTP-binding proteins. (1991) (9)
Endogenous GABA released into the fourth ventricle of the rat brain in vivo is enhanced by noxious stimuli (1988) (8)
Opioid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (8)
Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator‐induced brain damage following cerebral ischemia (2020) (8)
Down-regulation of AMPA-type glutamate receptor gene expression during goldfish optic nerve regeneration. (1995) (8)
Kyotorphin has a novel action on rat cardiac muscle. (2006) (8)
Computer Ethics Video Clips for University Students in Japan from 2003 until 2013 (2014) (8)
Presynaptic mediation by alpha 2-, beta 1- and beta 2-adrenoceptors of endogenous noradrenaline and dopamine release from slices of rat hypothalamus. (1983) (8)
In Vivo Signal Transduction of Tetrodotoxin-Sensitive Nociceptive Responses by Substance P Given into the Planta of the Mouse Hind Limb (1998) (8)
Exercise before or after refeeding prevents refeeding-induced recovery of cell size after fasting with a different pattern of metabolic gene expressions in rat epididymal adipocytes. (2007) (8)
ERRATUM: Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling (2004) (7)
Opioid mu- and kappa-receptor mediate phospholipase C activation through Gi1 in Xenopus oocytes. (1995) (7)
EDTA-insensitive deacylation of phosphatidylinositol in porcine platelet membranes. (1993) (7)
Inhibitory effects of the analgesic neuropeptides kyotorphin and neo-kyotorphin on enkephalin-degrading enzymes from monkey brain. (1986) (7)
Lysophosphatidic acid as the initiator of neuropathic pain. (2006) (7)
N‐bis(methylthio)methylene derivatives. 5. New synthesis of 2‐aminoindolizine and related compounds via a formal [3 + 3] cycloaddition reaction using N‐bis(ethoxycarbonylmethylthio)methylenephenylsulfonamides (1992) (7)
Protein kinase C inhibitor potentiates the agonist-induced GTPase activity in COS cell membranes expressing δ-opioid receptor (1995) (6)
First Cumulant of the Dynamic Structure Factor for Polymers in Θ Solvents. Effects of Chain Stiffness and Local Chain Conformation (2006) (6)
Effects of various mu- and delta-opioid ligands on food intake in the meat-type chick. (2005) (6)
IDENTIFICATION OF A NEW OPIOID PEPTIDE FROM THE BOVINE BRAIN AND ITS MECHANISM OF ACTION (1980) (6)
Role of beta-adrenoceptors in the expression of morphine withdrawal signs. (1994) (6)
A Met-enkephalin releaser (kyotorphin)-induced release of plasma membrane-bound Ca2+ from rat brain synaptosomes (1987) (6)
Feeding responses to mu-, delta- and kappa-opioid receptor agonists in the meat-type chick. (2004) (5)
[Anti-opioid action of glutamate-NMDA receptor systems underlying morphine analgesic tolerance]. (2009) (5)
Chronic generalized pain disrupts whole brain functional connectivity in mice (2021) (5)
Lysophosphatidic Acid Receptor 1- and 3-Mediated Hyperalgesia and Hypoalgesia in Diabetic Neuropathic Pain Models in Mice (2020) (5)
Deployment of Multilanguage Security Awareness Education Online Course by Federated Moodle in Japan (2017) (5)
Multiple forms of AMPA-type glutamate receptor mRNA phenotypes in goldfish retina and tectum. (1997) (5)
[Animal models and peripheral nociception tests for the study of neuropathic pain]. (2001) (5)
Tyrosyl-tRNA synthetase: A potential kyotorphin synthetase in mammals (2018) (5)
Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR2A/ε1, an NMDA receptor subunit (2000) (5)
Effects of acute nicotine on catecholamine turnover in various rat brain regions. (1989) (5)
Synthesis and analgesic activity of neo-kyotorphin analogs. (1985) (5)
Ifenprodil: protective effect in experimental cyanide poisoning. (1976) (4)
Beneficial actions of prothymosin alpha-mimetic hexapeptide on central post-stroke pain, reduced social activity, learning-deficit and depression following cerebral ischemia in mice (2020) (4)
Ecto-F0/F1 ATPase as a novel candidate of prothymosin α receptor (2018) (4)
Effects of yohimbine on endogenous noradrenaline release from hypothalamus and brainstem slices of spontaneously hypertensive rats. (1984) (4)
Gγ7-specific prothymosin alpha deletion causes stress- and age-dependent motor dysfunction and anxiety. (2019) (4)
Editorial: Differences in Pain Biology, Perception, and Coping Strategies: Towards Sex and Gender Specific Treatments (2021) (4)
Experimental evidence for the involvement of F0/F1 ATPase and subsequent P2Y12 receptor activation in prothymosin alpha-induced protection of retinal ischemic damage. (2020) (4)
Protein kinase C inhibitor potentiates the agonist-induced GTPase activity in COS cell membranes expressing delta-opioid receptor. (1995) (3)
Identification of prothymosin-alpha1, the necrosis–apoptosis switch molecule under the in vitro ischemia condition (2007) (3)
Cellular Mechanisms Underlying Morphine Analgesic Tolerance and Hyperalgesia (2009) (3)
G(i1) and G(oA) differentially determine kinetic efficacies of agonists for kappa-opioid receptor. (2000) (3)
Inter-helical Electrostatic Interaction and Rotameric Signatures in Activated Sphingosine-1-Phosphate Receptor 1 (2015) (3)
Review of Kyotorphin Research: A Mysterious Opioid Analgesic Dipeptide and Its Molecular, Physiological, and Pharmacological Characteristics (2021) (3)
Mirtazapine, an α2 Antagonist-Type Antidepressant, Reverses Pain and Lack of Morphine Analgesia in Fibromyalgia-Like Mouse Models (2020) (3)
Secreted PLA2-III is a possible therapeutic target to treat neuropathic pain. (2021) (3)
The effects of prostaglandin E1 on the pepsin activities in gastric mucosa and juice. (1987) (3)
Summary of the Fibromyalgia Research Symposium 2016 in Nagasaki (2017) (3)
[Signal transduction of cloned opioid receptors]. (1994) (3)
Quiz Making Activities Using the Multi-Mouse Quiz System in an Elementary School (2013) (3)
The effects in the excess administration of prostaglandin E1 on the indicator enzymes of organella membrane in gastric mucosa. (1987) (3)
[Molecular pharmacology of opioid receptor mechanisms]. (1989) (3)
High-field optical spectroscopy of the chromium spinel CdCr2O4 (2014) (3)
Purified opioid mu-receptor is of a different molecular size than delta- and kappa-receptors. (1987) (3)
Lysophosphatidic acid3 receptor-mediated feed-forward production of lysophosphatidic acid : an initiator of nerve injury-induced neuropathic pain (2015) (3)
ALTERED BASAL RELEASE AND PRESSOR EFFECT OF L‐DOPA IN THE ROSTRAL VENTROLATERAL MEDULLA OF SPONTANEOUSLY HYPERTENSIVE RATS (1995) (3)
Is BoNT/B useful for pain treatment? (2014) (2)
Protein kinase inhibitor potentiates opioid delta-receptor currents in Xenopus oocytes. (1994) (2)
Diminished alpha 2-adrenoceptor-mediated modulation of noradrenergic neurotransmission in the posterior hypothalamus of spontaneously hypertensive rats. (1986) (2)
Producing Video Clips for Information Ethics and Security in Higher Education (2017) (2)
[Isolation and analgesic mechanism of the opioid analgesic neuropeptide, kyotorphin (Tyr-Arg)]. (1985) (2)
Nuclear Magnetic Relaxation of Oligo- and Poly(α-methylstyrene)s in Dilute Solution (2005) (2)
Opioid receptors in GtoPdb v.2021.3 (2021) (2)
Author response: Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling (2015) (2)
Antiamnesic Action of Cromakalim, A Potassium Channel Opener, in Mice Treated with Hypoxia- and Cerebral Ischemia-Type Stress Stimuli (1998) (2)
Blockade of analgesic effects following systemic administration of N-methyl-kyotorphin, NMYR and arginine in mice deficient of preproenkephalin or proopiomelanocortin gene (2018) (2)
PRESYNAPTIC REGULATION OF ENDOGENOUS CATECHOLAMINE RELEASE FROM SLICES OF RAT HYPOTHALAMUS-IN SPECIAL REFERENCE TO ROLES OF ADRENALINE (1983) (2)
Attempts to classify dependence-liable drugs by using a simple drug-discrimination test in mice. (1998) (2)
Allodynia by Splenocytes From Mice With Acid-Induced Fibromyalgia-Like Generalized Pain and Its Sexual Dimorphic Regulation by Brain Microglia (2020) (2)
[Gene expression of human eukaryotic initiation factor-4E for protein synthesis and study of its recognition mechanism of mRNA cap structure]. (1995) (2)
Kyotorphin-specific receptor coupled to Ca2+ mobilizing mechanisms (1987) (1)
Stacking interactions between protonated nucleic acid bases and aromatic amino acids: spectroscopic and structural analyses of m3CMP-tryptophan derivative complex. (1989) (1)
[Molecular mechanisms of pain]. (2001) (1)
Drugs for the treatment and prevention of neurogenic pain (2001) (1)
[Pain and QOL--morphine-tolerance and morphine-resistant neuropathic pain]. (2003) (1)
A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis (2021) (1)
Lysophosphatidic acid receptor type‐1 mediates brain activation in micro‐positron emission tomography analysis in a fibromyalgia‐like mouse model (2022) (1)
[Lysophosphatidic Acid Receptor Signaling Underlying Chronic Pain and Neuroprotective Mechanisms through Prothymosin α]. (2019) (1)
Annexin A2 Flop-Out Mediates the Non-Vesicular Release of DAMPs/Alarmins from C6 Glioma Cells Induced by Serum-Free Conditions (2021) (1)
26 Neurotransmitters V Presynaptic mechanismThe involvement of enhanced Ca2+ channel activation and substance P release in morphine withdrawal jumping (1986) (1)
Therapeutic and adverse actions of L-DOPA. Nanomolar L-DOPA induces basal L-glutamate release in intact striata and its augmentation in 6-OHDA-lesioned striata of awake rats. (1996) (1)
µ-Opioid Receptor (1990) (1)
[Kyotorphin as an enkephalin releasing factor (author's transl)]. (1981) (1)
Recent advances in understanding of various chronic pain mechanisms through lysophosphatidic acid (LPA) receptor signaling (2012) (1)
[Neuronal death mode switch and neurogenesis as in vivo neuroprotection]. (2002) (1)
Evidence for a dopamine receptor subtype sensitive to combination of D1 with D2 antagonist in measurement of G-protein activity using rat striatal membranes. (1994) (1)
Opioid receptor coupling to Gi-phospholipase C activation in Xenopus oocytes and homologous desensitization mechanisms through phosphorylation (1994) (1)
The specific opioid kappa-agonist U-50,488H inhibits low Km GTPase. (1987) (1)
Lysophosphatidic Acid and Neuropathic Pain: Demyelination and LPA Biosynthesis (2013) (1)
Descriptor-based Fitting of Lysophosphatidic Acid Receptor 3 Antagonists into a Single Predictive Mathematical Model (2014) (1)
Affinity cross-linked delta-opioid receptor in NG108-15 cells is low molecular weight (25 kDa) and coupled to GTP-binding proteins. (1992) (1)
Functional coupling of opioid μ-, δ- and κ-receptors with GTP-binding proteins (1988) (1)
L-DOPA receptor function observed in 6-OHDA-lesioned Parkinson's disease model rats (1994) (1)
Homologous and heterologous desensitization of δ-opioid receptor in Xenopus oocytes, COS-cells and guinea pig striatal membranes (1995) (1)
L-DOPA releases endogenous GABA during microdialysis of the nucleus tractus solitarii area in anesthetized rats (1994) (1)
Protein Kinase C-Mediated Inhibition of m-Opioid Receptor Internalization and Its Involvement in the Development of Acute Tolerance to Peripheral m-Agonist Analgesia (2001) (1)
Involvement of SNARE Protein Interaction for Non-classical Release of DAMPs/Alarmins Proteins, Prothymosin Alpha and S100A13 (2020) (1)
Hexapeptide derived from prothymosin alpha attenuates cisplatin-induced acute kidney injury (2020) (1)
[Novel sensory fiber-specific nociception test with the Neurometer]. (2008) (1)
Dynamic Depolarized Light Scattering by Oligo- and Poly(α-methylstyrene)s in Dilute Solution (2005) (1)
In vivo signal transduction of peripherally-originated nociception in nociceptin receptor or substance P K O mice (1998) (1)
History of Steel Sleepers and the Latest Developments (2017) (1)
Interleukin-1β Plays Key Roles in LPA-Induced Amplification of LPA Production in Neuropathic Pain Model (2013) (0)
SYNTHESIS AND ANALGESIC ACTIVITY OF NEO-KYOTORPHIN ANALOGS (1985) (0)
Feed-forward system of peripheral and central chronic pain through lysophosphatidic acid (2010) (0)
Descriptor-based Fitting of LPA3 Inhibitors into a Single Predictive Mathematical Model (2014) (0)
Reconstitution of opioid receptor and GTP-binding protein. (1989) (0)
Pilocarpine suppresses hyperalgesia induced by intermittent cold stress (ICS) as an experimental fibromyalgia model in mice (2012) (0)
Insulin receptor-PKC- γ signaling mediates inhibition of hypoxia-induced necrosis of cortical neurons (2005) (0)
The Effect of Endurance Training on Secreting Adipocyokine (2000) (0)
Intermittent psychological (Empathy) stress-induced generalized pain syndrome in mice mimics pathophysiological and pharmacotherapeutic characters in fibromyalgia in clinic (2018) (0)
Brain-immune system and its maintenance of brain pain memory in fibromyalgia (2020) (0)
Title Prolonged gabapentin analgesia in an experimental mouse model offibromyalgia (2016) (0)
The role of endogenous chaperone protein RTP4 in Opioid Receptor Heteromer Regulation (2018) (0)
[Biosynthesis of kyotorphin, a dipeptidic neuromodulator]. (1989) (0)
SUBCELLULAR LOCALIZATION OF ANALGESIC DIPEPTIDE, KYOTORPHIN (TYR-ARG) IN THE RAT BRAIN (1981) (0)
A new high affinity dynorphin a binding site in the guinea pig cerebellum (1994) (0)
Alpha 1-antitrypsin and hepatic fibrosis. (1989) (0)
Title Loss of spinal substance P pain transmission under the condition of LPA 1 receptor-mediated neuropathic pain (2017) (0)
STUDIES ON PEPTIDES. XCIV. SYNTHESIS AND ACTIVITY OF KYOTORPHIN AND ITS ANALOGS (1980) (0)
NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice (2015) (0)
Molecular basis of morphine tolerance (2000) (0)
N‐Bis(methylthio)methylene Derivatives. Part 7. Syntheses and Reactions of Synthetic Equivalents of New 1,3‐Dipolar Reagents Using N‐ Bis(methylthio)methylene Derivatives. (1996) (0)
1D07 Effect of acute bout of exercise on serum level of granulysm, a cytolytic product of NK cells (2003) (0)
Protein kinase C-sensitive acute morphine tolerance and receptor internalization through dynamin (2000) (0)
Prothymosin α-derived hexapeptide prevents the brain damage and sequelae due to ischemia-hemorrhage (2022) (0)
Lysophosphatidic acid (LPA) involvement in central post-stroke pain (CPSP) (2018) (0)
Inositol 1,4,5-trisphosphate activates Ca2+ channels in the plasma membranes of rat brain nerve terminals. (1991) (0)
333 Species difference of opioid delta receptor-mediated signal transduction in synaptic membranes (1993) (0)
Prothymosin α Plays Role as a Brain Guardian through Ecto-F1 ATPase-P2Y12 Complex and TLR4/MD2 (2023) (0)
In vivo signal transduction of peripheral nociceptive and analgesic mechanisms (1998) (0)
310 Signal transduction of delta opioid receptor in Xenopus oocytes (1993) (0)
δ-, μ-, κ-Opioid receptors mediate activation of phospholipase C through Gi1 in Xenopus oocytes (1995) (0)
Neuronal plasticity in various neuropathic pain model mice (2000) (0)
Tonic Basal Release of Endogenous L-DOPA from the Nucleus Tractus Solitarii is Attenuated in Spontaneously Hypertensive Rats (1994) (0)
Prothymosin-alpha1 prevents neuronal necrosis by reversing the decreased membrane localization of GLUT (2007) (0)
Inhibition f Tumor Necrosis Factor-ct Leaf Extraet Production byOrally Administering a Perilla (2018) (0)
S9-5 Neuronal plasticity in the brain specific locus in morphine-induced tolerance and dependence(SYMPOSIUM 9: MOLECULAR MECHANISMS OF DRUG DEPENDENCE)(Proceedings of the 31st Annual Meeting) (2004) (0)
Effects of OPC-14597 on dopamine receptors in rat striata (1994) (0)
On the Confirmation Method of the User's Record of the GakuNinMoodle (2018) (0)
Differential sensory fiber specificity and LPA receptor-involvement between partial sciatic nerve injury-induced and high-fat diet-induced neuropathic pain (2018) (0)
Down-regulation of AMPA-type glutamate receptor gene expression in goldfish visual system during regeneration of optic nerve (1992) (0)
3P14:The effect of exercise-training on the generation of nitric oxide in pancreatic islet of Langerhans (2002) (0)
ALPHA_2- AND BETA-ADRENOCEPTOR-MEDIATED MODULATION OF NORADRENALINE RELEASE FROM SLICES OF HYPOTHALAMUS AND BRAINSTEM IN SPONTANEOUSLY HYPERTENSIVE RATS (1985) (0)
Involvement of lysophosphatidic acid (LPA) in tPA–induced central post stroke pain (CPSP) in mice (2018) (0)
Epigenetic gene silencing underlying negative symptoms in neuropathic pain (2010) (0)
Room B, 10/16/2000 2: 00 PM - 4: 00 PM (PS) The Role of Receptor Subtypes in Bradykinin Hyperalgesia in Neuropathic Mice A-923 (2000) (0)
[Cancer pain model and morphine analgesia]. (2007) (0)
[Sigma (sigma) receptor and neurosteroids]. (1999) (0)
LPA receptor signaling plays a definitive role in pain memory mechanisms in mouse models for neuropathic pain and fibromyalgia (2017) (0)
Lysophosphatidic acid 3 (LPA3) receptor-mediated LPA production via microglial activation underlies the initial mechanisms of nerve injury-induced neuropathic pain (2011) (0)
PD-6 Neurosteroid-induced nociception through a histamine release is regulated by endocrine disrupting chemicals (2003) (0)
Mechanism of the analgesic action of kyotorphin: Metenkephalin-releasing and enkephalinase inhibitory effect. (1980) (0)
Brain opioid-mediated analgesia by systemic administration of dipeptide kyotorphin analog (2018) (0)
THE OREXIGENIC EFFECT OF GONADOTROPIN-INHIBITING HORMONE IS MEDIATED BY OPIOID SYTEM IN THE BRAIN OF CHICKS (2007) (0)
N‐Bis(methylthio)methylene Derivatives. Part 5. New Synthesis of 2‐ Aminoindolizine and Related Compounds via a Formal (3 + 3) Cycloaddition Reaction Using N‐Bis(ethoxycarbonylmethylthio) methylenephenylsulfonamides. (1992) (0)
Protective actions of potassium channel openers on ischemia-induced amnesia and apoptosis of hippocampal neurons in mice (1997) (0)
Resistance to morphine analgesia and its underlying mechanisms in an experimental mouse model of fibromyalgia (2012) (0)
Two different activities of phospholipase A2 in porcine aortic cytosol. (1996) (0)
3P11:Effect of single bout exercise on adipocyte lipolysis(II) (2002) (0)
Molecular mechanisms for neuropathic pain–lysophosphatidic acid as the initiator (2006) (0)
614 Cloning and characterization of survival-related genes in rat brain primary culture by differential display method (1997) (0)
Transmitter-like L-DOPA mediates tonic vasopressor control in the rat rostral ventrolateral medulla and its tonic basal release is enhanced in spontaneously hypertensive rats. (1994) (0)
Presynaptic Modulation of Norepinephrine Release in the Hypothalamus and Brainstem of Spontaneously Hypertensive Rats (1984) (0)
Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR(2)A/epsilon(1), an NMDA receptor subunit. (2000) (0)
Subtypes of presynaptic alpha beta dopamine receptor mediating regulation of noradrenaline and dopamine release in the rat hypothalamus (1983) (0)
Presynaptic α2-, β- and DA-receptor-mediated mechanisms on endogenous catecholamine release from rat hypothalamic slices and their location and physiological roles. (1983) (0)
[Prothymosinα, as a neuroprotective DAMPs/Alarmins molecule]. (2018) (0)
Peripheral Beta-2 Adrenergic Receptors Mediate the Sympathetic Efferent Activation from Central Nervous System to Splenocytes in a Mouse Model of Fibromyalgia (2023) (0)
Epigenetic regulation in the neuronal plasticity in chronic pain (2009) (0)
Altered basal release and pressor effect of L-DOPA in the rostral ventrolateral medulla of spontaneously hypertensive rats. (1995) (0)
Effect of methadone analgesia in morphine-insensitive chronic pain (2019) (0)
APOPTOSIS-INHIBITORY FACTORS, AIF-20 AND AIF-22, AND ITS SIGNAL TRANSDUCTION (1996) (0)
Intermittent cold stress-induced experimental fibromyalgia model in mice - pharmacology and neurobiology (2012) (0)
Kyotorphin (Tyrosine-Arginine) Causes the Pertussis Toxin-sensitive GPCR-mediated Attenuation of Cardiomyocyte Beating (2005) (0)
Analysis for biphasic effects of dopaminergic agonists on the release of endogenous noradrenaline from rat hypothalamic slices. (1985) (0)
Novel receptor mechanisms of prothymosin alpha, a neuroprotective DAMPs molecule (2018) (0)
Drug discovery screening based on epigenetic control of COPD – Benserazide inhibits the prothymosin α-H1 histone interaction (2020) (0)
Central effect of metformin on food intake and glucose regulation in mice (2014) (0)
DIRECT NUMERICAL SIMULATION OF BLUFF BODY FLOWS USING NON-STAGGERED GRIDS (2000) (0)
The Role of Receptor Subtypes in Bradykinin Hyperalgesia in Neuropathic Mice (2000) (0)
Prothymosin-alpha1 switches the neuronal necrosis to neurotrophin-reversible apoptosis (2007) (0)
[Molecular pharmacology and physiology of nociceptin]. (1999) (0)
Different modes of coupling of delta-opioid receptors with GTP-binding proteins in membrane preparations from guinea-pig striatum and leal myenteric plexus (1990) (0)
REVIEW — Current Perspective — Neurobiology of the Edg 2 Lysophosphatidic Acid Receptor (2001) (0)
Involvement of Enhanced Gene Expression of Anti-Opioid Systems in Morphine Tolerance and Dependence (2002) (0)
Additional file 2: of Subcellular dissemination of prothymosin alpha at normal physiology: immunohistochemical vis-a-vis western blotting perspective (2016) (0)
Lipid Mediator LPA-Induced Demyelination and Self-Amplification of LPA Biosynthesis in Chronic Pain Memory Mechanisms (2015) (0)
Protein Kinase C-Mediated Acute Tolerance to Peripheral m-Opioid Analgesia in the Bradykinin-Nociception Test in Mice 1 (2000) (0)
Creation of the Immunosensor Protein (Artificial Receptor) Whose Protein Kinase Activity Can Respond to Antigen (1992) (0)
Brain α2-adrenoceptors and blood pressure. (1985) (0)
Lysophosphatidic acid (LPA) receptor: Pathophysiology and pharmacotherapy in chronic pain (2018) (0)
[Opioid receptors and GTP-binding proteins]. (1990) (0)

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