Hiroshi Yamazaki
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Computer Science
Hiroshi Yamazaki's Degrees
- PhD Computer Science Imperial University of Japan
- Masters Computer Science Kyoto University
- Bachelors Computer Science Osaka University
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(Suggest an Edit or Addition)Hiroshi Yamazaki's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. (1994) (2898)
- Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. (1996) (832)
- Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. (1992) (380)
- Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes. (1997) (306)
- Activation and detoxication of aflatoxin B1. (1998) (299)
- Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs. (1996) (267)
- Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens. (1992) (256)
- Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes (1999) (247)
- Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli. (2002) (245)
- Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. (2016) (244)
- Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1. (1998) (203)
- Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. (2004) (202)
- Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes. (1995) (201)
- Lack of Electron Transfer from Cytochrome b5 in Stimulation of Catalytic Activities of Cytochrome P450 3A4 (1996) (195)
- Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes. (1998) (188)
- Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions. (2000) (186)
- Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes. (1998) (174)
- A significant role of human cytochrome P450 2C8 in amiodarone N-deethylation: an approach to predict the contribution with relative activity factor. (2000) (172)
- Oxidation of xenobiotics by recombinant human cytochrome P450 1B1. (1997) (171)
- Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans (2001) (168)
- Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans (1997) (163)
- Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes. (1999) (159)
- Stepwise Reduction of gem-Dihalocyclopropanes with Tri-n-butyltin Hydride1 (1963) (159)
- Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug–drug interactions (2000) (152)
- Regio- and stereocontrolled dimerization of tert-butylacetylene to (Z)-1,4-di-tert-butylbutatriene by ruthenium catalysis. Reaction mechanism involving alkynyl-vinylidene coupling and rearrangement of the metal-bound C4 unit (1991) (152)
- Heterogeneous Ni Catalyst for Direct Synthesis of Primary Amines from Alcohols and Ammonia (2013) (152)
- Molecular Cloning of a Novel Human Collectin from Liver (CL-L1)* (1999) (146)
- Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate. (2001) (143)
- Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations. (1997) (142)
- Ethnic-related differences in coumarin 7-hydroxylation activities catalyzed by cytochrome P4502A6 in liver microsomes of Japanese and Caucasian populations. (1996) (136)
- Cobalt metallacycles. 11. On the transformation of bis(acetylene)cobalt to cobaltacyclopentadiene (1983) (135)
- A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur. (2002) (133)
- Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples. (1997) (133)
- Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions. (1997) (133)
- Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer. (1996) (131)
- Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes (1996) (129)
- Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates. (1995) (129)
- Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population. (2008) (126)
- Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes. (2007) (121)
- Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes. (1994) (121)
- Characterization of cytochrome P-450 2B6 in human liver microsomes. (1993) (118)
- Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R- and S-warfarin enantiomers. (1997) (116)
- Study of intramolecular sensitization and other excited-state pathways in orthometalated azobenzene complexes of palladium(II) (1985) (114)
- 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes. (1996) (108)
- Cobalt metallocycles : I. One-step and stepwise synthesis of cobaltacyclopentadiene complexes from acetylenes (1977) (108)
- Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. (2010) (107)
- Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase. (2001) (103)
- Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. (1994) (103)
- Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes. (1999) (101)
- Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities (1995) (101)
- In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians. (1996) (100)
- Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function (2011) (99)
- Use of Cellulosic Substrates for the Microbial Treatment of Acid Mine Drainage (1994) (99)
- Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes. (2000) (98)
- Nicotine metabolism and CYP2A6 allele frequencies in Koreans. (2001) (98)
- Identification of a novel polymorphic enhancer of the human CYP3A4 gene. (2004) (97)
- Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage (2002) (96)
- Cytotoxicity and apoptosis produced by troglitazone in human hepatoma cells. (2001) (95)
- Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity. (1995) (95)
- Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450. (2015) (95)
- Acetylene .pi.-Coordination, Slippage to .sigma.-Coordination, and 1,2-Hydrogen Migration Taking Place on a Transition Metal. The case of a Ru(II) Complex as Studied by Experiment and ab Initio Molecular Orbital Simulations (1994) (95)
- Two Naturally Occurring Terpenes, Dehydrocostuslactone and Costunolide, Decrease Intracellular GSH Content and Inhibit STAT3 Activation (2011) (91)
- Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs. (1999) (90)
- Prediction of in vivo drug clearance from in vitro data. II: Potential inter-ethnic differences (2006) (87)
- Facile Fabrication of ZSM-5 Zeolite Catalyst with High Durability to Coke Formation during Catalytic Cracking of Paraffins (2013) (87)
- Inhibitory Potencies of 1,4-dihydropyridine Calcium Antagonists to P-glycoprotein-Mediated Transport: Comparison with the Effects on CYP3A4 (2000) (85)
- Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009). (1992) (85)
- Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype. (2014) (85)
- Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport. (2001) (84)
- Regioselective hydroxylation of steroid hormones by human cytochromes P450 (2015) (83)
- Asymmetric Methoxyselenenylation of Alkenes with Chiral Ferrocenylselenium Reagents (1997) (83)
- Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes. (1999) (83)
- Evidence for a "carbene-like" intermediate during the reaction of methoxy species with light alkenes on H-ZSM-5. (2011) (82)
- Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes. (1997) (81)
- Isocyanide insertion and related reactions (1972) (80)
- Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5. (2008) (80)
- Ruthenium-catalysed disproportionation between vinylsilanes and mono-substituted alkenes via silyl group transfer (1991) (80)
- X-ray structures and far-infrared and Raman spectra of tetrahedral thiophenolato and selenophenolato complexes of zinc(II) and cadmium(II) (1988) (80)
- Preparations of σ-bonded alkyl-, aryl- and alkynylnickel compounds (1966) (79)
- Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes (2000) (78)
- Formation of a novel quinone epoxide metabolite of troglitazone with cytotoxicity to HepG2 cells. (2002) (76)
- Human cytochrome P450 2A13 efficiently metabolizes chemicals in air pollutants: naphthalene, styrene, and toluene. (2008) (76)
- Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation. (1995) (76)
- Studies on interaction of isocyanide with transition metal complexes (1975) (76)
- Highly sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM3009 having high O‐acetyltransferase and nitroreductase activities (1993) (75)
- CYP2A13 expressed in human bladder metabolically activates 4‐aminobiphenyl (2006) (75)
- Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes. (1999) (74)
- One-Electron Reduction of Aromatic Ketones by Low-Valent Lanthanides. Isolation, Structural Characterization, and Reactivity of Lanthanide Ketyl Complexes (1998) (73)
- Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes. (1994) (73)
- Decreased coumarin 7-hydroxylase activities and CYP2A6 expression levels in humans caused by genetic polymorphism in CYP2A6 promoter region (CYP2A6*9). (2003) (73)
- Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4. (2000) (73)
- Preparations and reactions of alkylcobalt complexes and diphenylacetylenecobalt complexes having a π-cyclopentadienyl group as a ligand (1970) (72)
- CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka. (2002) (70)
- Transient trimethylaminuria related to menstruation (2007) (70)
- Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization (1992) (69)
- In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone. (2000) (69)
- Cobalt metallocycles. 6. Preparation and structure of cobaltacyclopentene complexes and their reactions with olefins and acetylenes (1979) (68)
- Direct Production of Propene from Methoxy Species and Dimethyl Ether over H-ZSM-5 (2012) (68)
- Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes. (1995) (68)
- Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes. (1996) (67)
- Purification, characterization, and molecular gene cloning of an antifungal protein from Ginkgo biloba seeds (2007) (67)
- Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5' modification, purification, spectral characterization, reconstitution conditions, and catalytic activities. (1995) (66)
- Oral L-Carnitine Supplementation Increases Trimethylamine-N-oxide but Reduces Markers of Vascular Injury in Hemodialysis Patients (2015) (65)
- Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of trimethylamine in Japanese trimethylaminuria patients. (2004) (65)
- Novel synthesis of heterocyclic compounds from acetylenes (1973) (65)
- Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: similarity of CYP3A5 with CYP3A4 but not CYP3A7. (2003) (64)
- Methodologies for investigating drug metabolism at the early drug discovery stage: prediction of hepatic drug clearance and P450 contribution. (2010) (64)
- Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system. (2011) (63)
- Cobalt metallocycles: II. Diels—alder type reaction of cobaltacyclopentadienes with olefins (1977) (63)
- Synthesis, characterization, and molecular structure of .mu.-ethynediyl complexes [X(PR3)MC.ident.CM(PR3)2X] (M = Pd, Pt; R = Me, Et, n-Bu; X = Cl, I) (1988) (62)
- CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes. (2013) (62)
- De novo formation characteristics of dioxins in the dry zone of an iron ore sintering bed. (2004) (62)
- Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes. (1999) (62)
- Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. (1998) (61)
- Concentration profiles of solids suspended in a stirred tank (1986) (61)
- Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors. (2007) (61)
- A model for coenzyme-metal ion-apoenzyme interactions: crystal structure of the ternary complex [(thiamine pyrophosphate)(1,10-phenanthroline)aquacopper]-dinitrate-water (1980) (60)
- Direct and sensitized valence photoisomerization of a substituted norbornadiene. Examination of the disparity between singlet- and triplet-state reactivities (1986) (60)
- Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase. (1996) (60)
- Synthesis of 2-oxo- and 2-imino-1,2-dihydropyridines by cobalt-catalyzed cyclocotrimerization of acetylenes with isocyanates and carbodiimides. (1977) (59)
- Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, and Physiologically-Based Pharmacokinetic Modeling in Toxicology. (2016) (59)
- Utility of non-human primates in drug development: Comparison of non-human primate and human drug-metabolizing cytochrome P450 enzymes. (2016) (58)
- Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes. (1998) (58)
- CYP3A5 Contributes significantly to CYP3A-mediated drug oxidations in liver microsomes from Japanese subjects. (2004) (58)
- Heterogeneous cobalt catalysts for the acceptorless dehydrogenation of alcohols (2013) (58)
- Genetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus Macaques (2010) (57)
- Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds. (1997) (57)
- A Novel Route to Mixed Transition-Metal Complexes (1972) (57)
- CYP2A6 genetic polymorphisms and liver microsomal coumarin and nicotine oxidation activities in Japanese and Caucasians (2000) (56)
- Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1. (2000) (55)
- Mixed-metal clusters of isocyanide containing a mercury atom in the center of a trigonal-prismatic platinum framework. Hg[Pt3(2,6-Me2C6H3NC)6]2 (1982) (55)
- Natural flavours production: a biotechnological approach (1986) (55)
- Production of flavor esters by immobilized lipase (1987) (55)
- High rates of substrate hydroxylation by human cytochrome P450 3A4 in reconstituted membranous vesicles: influence of membrane charge. (1996) (54)
- Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities. (2013) (54)
- Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6. (2001) (54)
- Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7 alpha- and coumarin 7-hydroxylations. (1994) (54)
- Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys (2011) (54)
- Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. (2003) (54)
- Heterotropic cooperativity in oxidation mediated by cytochrome p450. (2008) (53)
- Excellent Stereoregular Isotactic Polymerizations of Propylene with C2-Symmetric Silylene-Bridged Metallocene Catalysts (1989) (53)
- Potential impact of cytochrome P450 3A5 in human liver on drug interactions with triazoles. (2010) (52)
- Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities (2007) (52)
- Synthesis and Characterization of BiFeO3–PbTiO3 Thin Films through Metalorganic Precursor Solution (2006) (52)
- Cobaltocene Catalyzed Synthesis of Pyridines (1976) (51)
- New phenylacetylene complexes of cobalt (1967) (51)
- Cobalt-catalyzed synthesis of pyridines from acetylenes and nitriles (1973) (51)
- Cobaltacyclopentadiene complexes as starting materials in the synthesis of substituted benzenes, cyclohexadienes, thiophenes, selenophenes and pyrroles (1975) (50)
- Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas. (2005) (49)
- Interactions of isocyanides with transition metal complexes. IX. Single and multiple insertion of isocyanide into palladium-to-carbon .sigma. bonds (1974) (49)
- Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes. (1996) (48)
- Functional polymer‐dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes (2015) (48)
- Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from tegafur in human liver. (2001) (47)
- Production of ethyl acetate from dilute ethanol solutions by Candida utilis. (1984) (47)
- In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais. (2006) (47)
- Pharmacokinetics of antifungal agent micafungin in critically ill patients receiving continuous hemodialysis filtration. (2007) (46)
- Lung tumorigenesis promoted by anti-apoptotic effects of cotinine, a nicotine metabolite through activation of PI3K/Akt pathway. (2012) (46)
- Well-Defined Metal Ketyl Complex: Sm(ketyl)(OAr)2(THF)2 and Its Reversible Coupling to a Disamarium(III) Pinacolate (1995) (46)
- A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system. (1996) (46)
- A population phenotyping study of three drug‐metabolizing enzymes in Kyushu, Japan, with use of the caffeine test (2002) (46)
- Double alkylation of carbon monoxide via free radicals : synthesis of unsymmetrical ketones (1991) (45)
- Preparation, properties, and some reactions of novel ruthenium thiolate complexes (1989) (45)
- REACTIONS OF BENZENES WITH ACETYLENES CATALYZED BY RHODIUM CARBONYL UNDER CARBON MONOXIDE (1979) (45)
- Synthesis of 2-Oxo-1,2-dihydropyridines by the Reaction of Cobaltacylopentadiene Complexes with Isocyanates (1977) (44)
- Human Blood Concentrations of Cotinine, a Biomonitoring Marker for Tobacco Smoke, Extrapolated from Nicotine Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling (2010) (44)
- Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1′-Hydroxylation (2011) (44)
- Neutral and cationic rhodium complexes of 2,6-disubstituted phenyl isocyanides. Crystal structure analysis of chlorotris(2,4,6-tri-tert-butylphenyl isocyanide)rhodium(I) and estimation of bulkiness in the isocyanide substituent (1979) (43)
- Oxidation of endobiotics mediated by xenobiotic-metabolizing forms of human cytochrome. (2009) (43)
- Aflatoxin B1 8,9-epoxide hydrolysis in the presence of rat and human epoxide hydrolase. (1997) (42)
- Aryl hydrocarbon hydroxylase represents CYP1B1, and not CYP1A1, in human freshly isolated white cells: trimodal distribution of Japanese population according to induction of CYP1B1 mRNA by environmental dioxins. (2003) (42)
- Four carbon component coupling reaction based on free-radical carbonylation: an easy access to .beta.-functionalized .delta.,.epsilon.-unsaturated ketones (1993) (42)
- Cytochrome P450-dependent drug oxidation activity of liver microsomes from Microminipigs, a possible new animal model for humans in non-clinical studies. (2009) (42)
- Some reactions of π-cyclopentadienylbis(triphenylphosphine) rhodium(I) (1974) (42)
- Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6. (2013) (42)
- Chemistry of mixed transition-metal complexes : II. Preparation of mixed transition-metal μ-diphenylphosphido complexes☆ (1971) (42)
- Species Differences in the Pharmacokinetic Parameters of Cytochrome P450 Probe Substrates between Experimental Animals, such as Mice, Rats, Dogs, Monkeys, and Microminipigs, and Humans (2015) (41)
- Excitation wavelength dependence of photodissociation and the secondary laser pulse photolysis of dimanganese decacarbonyl (1986) (41)
- Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans (2014) (41)
- Hepatocyte nuclear factor-1alpha is a causal factor responsible for interindividual differences in the expression of UDP-glucuronosyltransferase 2B7 mRNA in human livers. (2002) (40)
- Organic reactions with rhodium carbonyl cluster catalysts (1983) (40)
- Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females. (2002) (40)
- Insertion reactions of isocyanides into nickel-to-carbon sigma bonds (1969) (40)
- Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. (2009) (40)
- Two novel haplotypes of CYP2D6 gene in a Japanese population. (2003) (39)
- Mutagenic activation of 3-methoxy-4-aminoazobenzene by mouse renal cytochrome P450 CYP4B1: cloning and characterization of mouse CYP4B1. (1995) (39)
- Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes (2003) (39)
- In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice. (2012) (39)
- Stepwise and reversible cleavage of the C-O double bond of diaryl ketones by lanthanide metals (1992) (39)
- The Dimerization of Butadiene in Methanol by a Palladium Complex Catalyst (1968) (39)
- Utilization of estimated physicochemical properties as an integrated part of predicting hepatic clearance in the early drug-discovery stage: Impact of plasma and microsomal binding (2009) (39)
- High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana (2005) (39)
- Cynomolgus Monkey CYP2D44 Newly Identified in Liver, Metabolizes Bufuralol, and Dextromethorphan (2010) (39)
- Drug Interactions of Thalidomide with Midazolam and Cyclosporine A: Heterotropic Cooperativity of Human Cytochrome P450 3A5 (2009) (38)
- Heteroleptic Lanthanide Complexes with Aryloxide Ligands. Synthesis and Structural Characterization of Divalent and Trivalent Samarium Aryloxide/Halide and Aryloxide/Cyclopentadienide Complexes. (1996) (38)
- CYP1D1, pseudogenized in human, is expressed and encodes a functional drug-metabolizing enzyme in cynomolgus monkey. (2011) (38)
- Twenty one novel single nucleotide polymorphisms (SNPs) of the CYP2A6 gene in Japanese and Caucasians. (2002) (38)
- Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations (2006) (38)
- Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population. (2007) (37)
- Reactions of N,N-dimethylbenzylamine complex of palladium(II) with isocyanides (1980) (37)
- NEW HETEROCYCLIC FIVE-MEMBERED METALLO-RING COMPLEXES OF COBALT AND RHODIUM (1973) (36)
- Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole (2015) (36)
- Mutagenic activation of carcinogenic N-nitrosopropylamines by rat liver: evidence for a cytochrome P-450 dependent reaction. (1985) (36)
- Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3) (2007) (36)
- Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate. (2010) (36)
- In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice. (2013) (36)
- Proteinase Inhibitor from Ginkgo Seeds Is a Member of the Plant Nonspecific Lipid Transfer Protein Gene Family1 (2008) (36)
- IR Characterization of Homogeneously Mixed Silica–Alumina Samples and Dealuminated Y Zeolites by Using Pyridine, CO, and Propene Probe Molecules (2013) (36)
- Interactions of tetrakis(-µ-carboxylato)dirhodium(II), an antitumour agent, with nucleic acid bases. X-Ray crystal structures of [Rh2(acetato)4(theophylline)2] and [Rh2(acetato)4(caffeine)2] (1980) (35)
- Evaluation of the toxicity of Salmonella selective media for shortening the enrichment period. (1993) (35)
- Interligand Interactions Affecting Site-Specific Metal Bonding. X-ray Crystal Structures of [Rh2(acetato)4(L)2], Where L = 2,4-Diamino-6-methyl-s-triazine, 2,6-Dimethyl-4-aminopyrimidine, and 2,6-Dimethylpyridine (1994) (35)
- Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes. (1993) (35)
- Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity. (2008) (34)
- Uridine diphosphate sugar-selective conjugation of an aldose reductase inhibitor (AS-3201) by UDP-glucuronosyltransferase 2B subfamily in human liver microsomes. (2004) (34)
- Ruthenium catalyzed dimerization of trimethysilylacetylene to 1,4-bis(trimethylsilyl)butatriene and its isomerization to (Z)-1,4-bis(trimethylsilyl)-1-buten-3-yne (1993) (34)
- Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys (2013) (34)
- Drug oxygenation activities mediated by liver microsomal flavin-containing monooxygenases 1 and 3 in humans, monkeys, rats, and minipigs. (2014) (34)
- Cobalt metallacycles. Part 5. Synthesis of pyridines from nitriles and acetylenes via cobaltacyclopentadienes (1978) (34)
- Induction of cytochrome P450 1B1 in lung, liver and kidney of rats exposed to diesel exhaust. (2001) (34)
- CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques. (2014) (34)
- Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model (2016) (33)
- Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry. (2010) (33)
- Electrochemical studies of organometallic compounds. 8. Electrochemical preparations and reactions of linear di- and trinuclear complexes of platinum and palladium (1993) (33)
- Improved catalytic activity of cyclopentadienylcobalt in the preparation of pyridines from acetylenes and nitriles (1985) (33)
- Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes. (1996) (33)
- Blood concentrations of acrylonitrile in humans after oral administration extrapolated from in vivo rat pharmacokinetics, in vitro human metabolism, and physiologically based pharmacokinetic modeling. (2010) (33)
- Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans. (2015) (33)
- Single, Double and Triple Insertion of Cyclohexyl Isocyanide into Methyl-Palladium Sigma Bond (1970) (32)
- Individual differences in pharmacokinetics and pharmacodynamics of anesthetic agent propofol with regard to CYP2B6 and UGT1A9 genotype and patient age. (2011) (32)
- Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004. (1996) (32)
- Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition. (2013) (32)
- Rhodium carbonyl-catalyzed activation of carbon-hydrogen bonds for application in organic synthesis.: V. phenylation of olefins with benzenes (1984) (32)
- Activation Energies for the Reaction of Ethoxy Species to Ethene over Zeolites (2010) (32)
- One-Step Block-Copolymerization of Ethylene with Styrene by C5Me5/ER-Ligated Samarium(II) Complexes (ER = OAr, SAr) (1998) (32)
- Microminipig, a non-rodent experimental animal optimized for life science research: in vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig. (2011) (32)
- Electrochemical preparation and characterization of binuclear palladium(I) complexes containing aromatic isocyanide and chelating diphosphine ligands (1993) (32)
- Simultaneous pharmacokinetics assessment of caffeine, warfarin, omeprazole, metoprolol, and midazolam intravenously or orally administered to Microminipigs. (2012) (31)
- Cobalt metallacycles. 8. Preparative and kinetic studies on the reactivity of cobaltacyclopentadienes with phosphites (1980) (31)
- Studies on interactions of isocyanides with transition metal complexes (1970) (31)
- Salmonella detection by the polymyxin-cloth enzyme immunoassay using polyclonal and monoclonal detector antibodies. (1996) (31)
- Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (fish odor syndrome): observations from Japanese patients. (2007) (31)
- Comparison of p450 enzymes between cynomolgus monkeys and humans: p450 identities, protein contents, kinetic parameters, and potential for inhibitory profiles. (2013) (30)
- Inhibitory effect of organic solvents on the mutagenicity of N-nitrosodialkylamines in Salmonella. (1985) (30)
- CHROMIUM TETRA-t-BUTOXIDE (1959) (30)
- Biomonitoring of Urinary Cotinine Concentrations Associated with Plasma Levels of Nicotine Metabolites after Daily Cigarette Smoking in a Male Japanese Population (2010) (30)
- Use of everted sacs of mouse small intestine as enzyme sources for the study of drug oxidation activities in vitro (2000) (30)
- Qualitative De Novo Analysis of Full Length cDNA and Quantitative Analysis of Gene Expression for Common Marmoset (Callithrix jacchus) Transcriptomes Using Parallel Long-Read Technology and Short-Read Sequencing (2014) (30)
- Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol (2006) (30)
- Dose-dependent Effects of Cigarette Smoke on Blood Biomarkers in Healthy Japanese Volunteers: Observations from Smoking and Non-smoking (2009) (30)
- Alprazolam as an In Vivo Probe for Studying Induction of CYP3A in Cynomolgus Monkeys (2010) (30)
- Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese. (2003) (30)
- Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling (2016) (30)
- Cobalt metallacycles. 12. Reaction of cobaltacyclopentadiene with nonacarbonyldiiron and octacarbonyldicobalt. Formation of dinuclear metal complexes (1983) (30)
- The binuclear iridium(II) hydride complex [(C(5)Me(5))Ir(mu-H)](2): a novel base for reversible deprotonation of acidic organic compounds and a unique catalyst for C--C bond cleavage of aromatic 1,2-diols and Michael additions. (2001) (30)
- Role of human N-acetyltransferases, NAT1 or NAT2, in genotoxicity of nitroarenes and aromatic amines in Salmonella typhimurium NM6001 and NM6002. (1999) (30)
- Some Organometallic Chemistry of Ruthenium(II) (1995) (29)
- A convergent enone synthesis. Three-component coupling of alkyl iodides, carbon monoxide, and allylstannanes by free-radical carbonylation (1991) (29)
- Plasma and Hepatic Concentrations of Chemicals after Virtual Oral Administrations Extrapolated Using Rat Plasma Data and Simple Physiologically Based Pharmacokinetic Models. (2018) (29)
- Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. (1999) (29)
- Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling. (2013) (29)
- The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage. (2017) (29)
- Effect of temperature and agitation on enrichment of Escherichia coli O157:H7 in ground beef using modified EC broth with novobiocin. (1997) (28)
- Cobaltacyclopentene complex as an intermediate in cobalt-catalyzed cooligomerization of diphenylacetylene with cyano olefins (1974) (28)
- Rigid-to-Flexible Conformational Transformation: An Efficient Route to Ring-Opening of a Tröger's Base-Containing Ladder Polymer. (2017) (28)
- Cobalt metallocycles: IV. Ring opening of cobaltacyclopentadienes by addition of SiH, SH, NH and CH to the diene moiety☆ (1978) (28)
- Reaction of a diphenylacetylene complex of cobalt with isocyanide. Novel metalloring formation (1975) (28)
- Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes. (1996) (28)
- Bis(triphenylphosphine)-π-cyclopentadienyl-cobalt(I) and -rhodium(I) (1971) (28)
- Two Novel CYP2D6*10 Haplotypes As Possible Causes of a Poor Metabolic Phenotype in Japanese (2009) (27)
- Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes (2015) (27)
- Molecular and functional characterization of flavin-containing monooxygenases in cynomolgus macaque. (2013) (27)
- Cobalt metallocycles. XIII: Preparation and X-ray crystallography of cobaltacyclopentadiene and dinuclear cobalt complexes (1984) (27)
- Crystal and Molecular Structure of (π-C5H5)Fe3(CO)7C2C6H5 Obtained from (π-C5H5)Fe(CO)2C≡CC6H5 with Fe2(CO)9 (1975) (27)
- Synthesis and x-ray structure analysis of the tetracapped octahedral ruthenium carbido cluster [N(PPh3)2]2[Ru10C(CO)24] (1989) (27)
- Inter-individual variation in flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors. (2009) (27)
- Limited effects of frequent CYP2D6*36-*10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population (2010) (27)
- Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs (2014) (27)
- REACTIONS OF ETHYLENE AND BENZENES CATALYZED BY RHODIUM CARBONYLS UNDER CARBON MONOXIDE. THE FORMATION OF STYRENES AND 3-PENTANONE (1979) (27)
- Improvement in the catalytic properties of ZSM-5 zeolite nanoparticles via mechanochemical and chemical modifications (2016) (26)
- Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling (2017) (26)
- A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin (2010) (26)
- Genotoxicity of a variety of azobenzene and aminoazobenzene compounds in the hepatocyte/DNA repair test and the Salmonella/mutagenicity test. (1986) (26)
- Interactions of isocyanides with transition metal complexes. VIII. Reactions of alkyl isocyanide with dicarbonyl-.pi.-cyclopentadienylalkyliron (1972) (26)
- In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice. (2011) (26)
- A 35-kDa protein binding to a cytosine-rich strand of hypervariable minisatellite DNA. (1992) (26)
- Thiamine-metal ion and thiamine-anion interactions. Crystal structure of Cu(thiamine)Br2 (1989) (26)
- Comparison of cytochrome P450 2D6 and variants in terms of drug oxidation rates and substrate inhibition. (2011) (26)
- Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats. (2001) (26)
- CO-breathing structure change and catalysis for oxygenate synthesis from carbon monoxide/hydrogen on supported ruthenium carbido [Ru6C] clusters: structural and chemical controls by interstitial carbido carbon (1994) (26)
- Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds. (2011) (26)
- Cytochrome P-450 forms and its inducibility by PCB isomers in black-headed gulls and black-tailed gulls (1992) (26)
- An anion-conductive microporous membrane composed of a rigid ladder polymer with a spirobiindane backbone (2016) (26)
- First Isolation of a Tris(ketyl) Metal Complex (1996) (25)
- Cobalt metallocycles: III. Thermolysis of cobaltacyclopentadiene complexes (1978) (25)
- Novel catalytic dimerization of t-butylacetylene to trans-1,4-di-t-butylbutatriene (1976) (25)
- STEREOSPECIFIC INTERACTIONS BETWEEN TETRAKIS(μ-CARBOXYLATO)DIRHODIUM ANTITUMOR AGENTS AND NUCLEIC ACID BASES. CRYSTAL STRUCTURE OF THE RHODIUM COMPLEX (RH2(ACETATO)4(AAMP).3.5H2O) (AAMP = 4-AMINO-5-(AMINOMETHYL)-2-METHYLPYRIMIDINE) (1984) (25)
- Synthesis and structure of the chloride and nitrate inclusion complexes of [16-pyrimidinium crown-4]4+ (1991) (25)
- Marmoset cytochrome P450 2D8 in livers and small intestines metabolizes typical human P450 2D6 substrates, metoprolol, bufuralol and dextromethorphan (2015) (25)
- Human biofluid concentrations of mono(2-ethylhexyl)phthalate extrapolated from pharmacokinetics in chimeric mice with humanized liver administered with di(2-ethylhexyl)phthalate and physiologically based pharmacokinetic modeling. (2015) (25)
- Transfer of Ketyls from Alkali Metals to Transition Metals. Formation and Diverse Reactivities of d-Block Transition-Metal Ketyls (1999) (25)
- Chemistry of mixed transition-metal complexes : VIII. Preparations of π-cyclopentadienyl(ferrocenylcyclobutadiene)cobalt complexes and 1,1′-(o-phenylene)ferrocenes (1977) (25)
- Simulation of Human Plasma Concentrations of Thalidomide and Primary 5-Hydroxylated Metabolites Explored with Pharmacokinetic Data in Humanized TK-NOG Mice. (2015) (25)
- Absorption Spectra of Metallic Complexes with Aromatic Molecules (1960) (25)
- Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus) (2016) (24)
- Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus) (2015) (24)
- Determination and prediction of permeability across intestinal epithelial cell monolayer of a diverse range of industrial chemicals/drugs for estimation of oral absorption as a putative marker of hepatotoxicity (2020) (24)
- Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens. (2004) (24)
- Syntheses and structures of methyl-, acetyl- and allyl-ruthenium carbidocarbonyl clusters (1990) (24)
- Inhibitory effects of azelastine and its metabolites on drug oxidation catalyzed by human cytochrome P-450 enzymes. (1999) (24)
- Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens. (1992) (24)
- Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans. (2010) (24)
- Phospholipase D activity of cytochrome P450 in human liver endoplasmic reticulum. (1999) (24)
- Mutagenic activation of betel quid-specific N-nitrosamines catalyzed by human cytochrome P450 coexpressed with NADPH-cytochrome P450 reductase in Salmonella typhimurium YG7108. (2005) (24)
- Cytochrome P450 reconstitution systems. (1998) (24)
- Simple and economical culture of Campylobacter jejuni and Campylobacter coli in CO2 in moist air. (1992) (24)
- CYP2A6 IS A PRINCIPAL ENZYME INVOLVED IN HYDROXYLATION OF 1,7-DIMETHYLXANTHINE, A MAIN CAFFEINE METABOLITE, IN HUMANS (2005) (24)
- Chemistry of mixed transition metal complexes III. Preparation and structure of new complexes of acetylenes coordinated on iron and nickel (1972) (24)
- A novel six-membered ruthenium metallocycle (1976) (23)
- Studies on interactions of isocyanides with transition-metal complexes. 30. X-ray crystal structure of dichlorobis(2,6-dimethylphenyl isocyanide)bis(pyridine)dipalladium. Unusual carbon-nitrogen-carbon bond angles and infrared spectrum in bridging isocyanide groups (1986) (23)
- Rat cytochrome p450 1A and 3A enzymes involved in bioactivation of tegafur to 5-fluorouracil and autoinduced by tegafur in liver microsomes. (2001) (23)
- Fifty Years of Cytochrome P450 Research (2014) (23)
- Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor. (2014) (23)
- Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytes. (2014) (23)
- Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide. (2014) (23)
- Reactions of µ-ethynediyl complexes of transition metals: selective double insertion of isocyanides and molecular structure of [Cl(Et3P)2PdCCC(NPh)C(NPh)Pd(PEt3)2Cl] (1991) (23)
- The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice (2013) (23)
- Human Blood Concentrations of Dichlorodiphenyltrichloroethane (DDT) Extrapolated from Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling (2010) (23)
- Bis(9-triptycyl)amines, a missing link between the corresponding methanes and ethers. An unconventional synthesis and influence of nitrogen configurational inversion on the coupled disrotatory trajectory (1986) (23)
- Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone (2017) (22)
- Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes. (1992) (22)
- A Convenient Synthesis of 3-Imino-2-phenylindazolines (1976) (22)
- Novel cyclic carbene complexes of iron (1974) (22)
- Novel crystal structure of ytterbium(II)–benzophenone dianion complex and its reaction with 2,6-di-tert-butyl-4-methylphenol (1992) (22)
- Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450 (2014) (22)
- Importance of cynomolgus monkeys in development of monoclonal antibody drugs. (2019) (22)
- Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey (2011) (22)
- X-ray studies on metal ion interactions with vitamins. 1. Crystal and molecular structure of the tetrakis(.mu.-acetato)bis(thiamin monophosphate)dirhodium(II) sesquihydrate complex: thiamin base-metal bonding (1985) (22)
- Mechanism of Decomposition of Surface Ethoxy Species to Ethene and Acidic OH Groups on H-ZSM-5. (2015) (22)
- Steric effects of ligands in silver(I) isocyanide complexes. Structure of Ag(2,4,6-t-Bu3C6H2NC)2(PF6) containing a bidentate PF6 ligand (1983) (22)
- A novel immunofluorescence capillary electrophoresis assay system for the determination of chloramphenicol in milk (1994) (22)
- Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo. (2015) (22)
- Poly(vinyl alcohol) as a blocking agent in enzyme immunoassays. (1994) (22)
- Formation, Structure, spectra, and reactivity of the adduct between (η5-Cyclopentadienyl)(1,2-dimethoxycarbonyl-1,2-ethylenedithiolato) rhodium(III) and Dimethyl acetylenedicarboxylate (1995) (22)
- On the Mechanism of Oligomerization of Propylene by (C5Me5)2MCl2/Methylalumoxane Catalysts (M = Zr, Hf) (1991) (21)
- Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation. (2012) (21)
- Stereoselectivity of human cytochrome p450 in metabolic and inhibitory activities. (2011) (21)
- Evaluation of cytochrome P450 inductions by anti-epileptic drug oxcarbazepine, 10-hydroxyoxcarbazepine, and carbamazepine using human hepatocytes and HepaRG cells (2016) (21)
- First Isolation of a Metal Ketyl in Aggregated Forms. X-ray Structures of Dimeric and Tetrameric Sodium Fluorenone Ketyl Complexes: [Na(μ2-η1-ketyl)(HMPA)2]2 and [Na(μ3-η1-ketyl)(HMPA)]4 (1996) (21)
- Human cytochrome P450 1A2 involvement in the formation of reactive metabolites from a species-specific hepatotoxic pyrazolopyrimidine derivative, 5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo[1,5-a]pyrimidine. (2009) (21)
- Eighteen novel polymorphisms of the CYP2A13 gene in Japanese. (2003) (21)
- Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay. (2001) (21)
- Cobalt Metallocycles. VII. η5-Cyclopentadienyl-η4-iminocyclopentadienecobalt Complexes from a Reaction of Cobaltacyclopentadienes with Isocyanides (1979) (21)
- Dichlorotetrakis(isocyanide)dipalladium(I) containing a metal-metal bond (1985) (21)
- Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes. (1994) (21)
- Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice (2017) (20)
- Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population. (2014) (20)
- Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes (2007) (20)
- Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population. (2012) (20)
- Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro–in vivo correlation (2015) (20)
- Three novel single nucleotide polymorphisms of the FMO3 gene in a Japanese population. (2006) (20)
- Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling. (2015) (20)
- Effect of iron and EDTA on ethyl acetate accumulation in Candida utilis (1984) (20)
- Crystal and molecular structure of 1,1'-(tetraphenyl-o-phenylene)ferrocene (1977) (20)
- Insertion of Isonitrile into Alkyl-Nickel Bonds (1968) (20)
- Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1 (1994) (20)
- Comparison of the Inhibitory Profiles of Itraconazole and Cimetidine in Cytochrome P450 3A4 Genetic Variants (2011) (20)
- Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay. (2002) (20)
- Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood. (2011) (20)
- Preparation of Pb(Zr, Ti)O3 Thin Films Using All Dipivaloylmethane Source Materials by Metalorganic Chemical Vapor Deposition (1992) (20)
- Metal ion-bridged intramolecular stacking interaction between the tryptophyl residue and the aromatic heterocyclic amine within the ternary complex (1,10-phenanthroline)(L-tryptophanato-O,N)copper(II) perchlorate–water (1/2.5): an X-ray study (1987) (20)
- Molecular structure of π-C5H5NiFe(CO)3Ph3PCCH (1975) (20)
- Genetic polymorphisms of drug‐metabolizing cytochrome P450 enzymes in cynomolgus and rhesus monkeys and common marmosets in preclinical studies for humans (2017) (19)
- Roles of CYP 2 A 6 and CYP 2 B 6 in nicotine C-oxidation by human liver microsomes (19)
- Physiologically based pharmacokinetic–pharmacodynamic modeling to predict concentrations and actions of sodium‐dependent glucose transporter 2 inhibitor canagliflozin in human intestines and renal tubules (2016) (19)
- Hepatic microsomal UDP‐glucuronosyltransferase (UGT) activities in the microminipig (2014) (19)
- Use of polymyxin-coated polyester cloth in the enzyme immunoassay of Salmonella lipopolysaccharide antigens. (1990) (19)
- Chemistry of mixed transition-metal complexes : IV. Preparation of tertiary phosphine derivatives of carbonyl-π-cyclopentadienyliron-μ-dicarbonyl-π-cyclopentadienylnickel☆ (1971) (19)
- Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6 (2015) (19)
- Unprecedented rhodium-mediated tetramerization of bulky terminal alkynes leading to hydropentalenylrhodium complexes (2001) (19)
- Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling. (2014) (19)
- The crystal and molecular structures of a novel μ-allyl palladium complex, μ-allyl-μ-iodo-bis(triphenylphosphinepalladium) benzene solvate (1972) (19)
- Potential for drug interactions mediated by polymorphic flavin-containing monooxygenase 3 in human livers. (2015) (19)
- Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13 (2016) (19)
- Conditional N-rasG12V expression promotes manifestations of neurofibromatosis in a mouse model (2007) (19)
- Cardiohemodynamic and Electrophysiological Effects of Anti-influenza Drug Oseltamivir In Vivo and In Vitro (2013) (19)
- (1, 3‐Butadiene‐1, 4‐Diyl)(η5‐Cyclopentadienyl)‐(Triphenylphosphine)Cobalt with Various Substituents (2007) (19)
- Interactions of isocyanides with transition metal complexes. X. Preparation and reactions of alkyliron complexes containing isocyanide (1974) (19)
- HOMOLOGATION OF METHANOL CATALYZED BY MIXED TRANSITION METAL CLUSTERS CONTAINING COBALT (1981) (19)
- Correlation of the two torsional degrees of freedom about the bonds connecting the bridgehead carbons to the sulfur atom in bis (9-triptycyl) sulfide (1987) (19)
- Systematic identification and characterization of glutathione S-transferases in cynomolgus macaque. (2013) (18)
- Studies on the Interaction of Isocyanides with Transition-metal Complexes. VII. Insertion Reactions of Isocyanide into Alkyl-platinum Sigma Bonds (1971) (18)
- Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes. (1996) (18)
- Mild trimethylaminuria observed in a Japanese cohort with liver damage. (2005) (18)
- A single-stranded DNA binding protein from mouse tumor cells specifically recognizes the C-rich strand of the (AGG:CCT)n repeats that can alter DNA conformation. (1992) (18)
- Lanthanoid Complexes with Hexamethylphosphoramide (HMPA) Ligand. Preparation and Crystal Structure of Ytterbium Complexes of HMPA, [Yb(H2O)5(HMPA)2]Cl3·H2O·HMPA and YbCl3 (HMPA)3 (1991) (18)
- Hydroconversion of methyl laurate over beta-zeolite-supported Ni–Mo catalysts: Effect of acid and base treatments of beta zeolite (2020) (18)
- Simple extraction of Campylobacter lipopolysaccharide and protein antigens and production of their antibodies in egg yolk. (1994) (18)
- Mutagenic activation of carcinogenic N-nitrosopropylamines by liver S9 fractions from mice, rats and hamsters: evidence for a cytochrome P-450-dependent reaction. (1986) (18)
- Studies on active substances in the herbs used for oketsu ("stagnant blood") in Chinese medicine. III. On the anticoagulative principles in curcumae rhizoma. (1985) (18)
- Application of polymyxin-coated polyester cloth to the semi-quantitation of Salmonella in processed foods. (1991) (18)
- Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals. (2009) (18)
- Mechanism‐based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo (2011) (18)
- Free-radical carbonylation. Conversion of aromatic halides to aldehydes (1990) (18)
- Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6. (2016) (18)
- Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase (2015) (17)
- Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl (2016) (17)
- [Genetic polymorphisms of drug metabolizing enzymes]. (2002) (17)
- Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats. (2020) (17)
- Rhodium carbonyl catalyzed carbonylation of unsaturated compounds. 2. Synthesis of 5-alkoxy-2(5H)-furanones by the carbonylation of acetylenes in alcohol (1983) (17)
- Chemistry of mixed transition-metal complexes : VII. Iron- and nickel-substituted cyclobutadiene complexes of cobalt☆ (1976) (17)
- Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling (2015) (17)
- Population pharmacokinetics of fluconazole after administration of fosfluconazole and fluconazole in critically ill patients (2012) (17)
- Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes. (1991) (17)
- Characterization of Microsomal Glutathione S-Transferases MGST1, MGST2, and MGST3 in Cynomolgus Macaque (2013) (17)
- Mechanism-based inhibition of CYP1A1 and CYP3A4 by the furanocoumarin chalepensin. (2013) (17)
- Polymorphisms of CYP2D17 in Cynomolgus and Rhesus Macaques: an Evidence of the Genetic Basis for the Variability of CYP2D-Dependent Drug Metabolism (2014) (16)
- Studies on Interactions of Isocyanides with Transition Metal Complexes. IV. Dicarbonyl(isocyanide)-π-cyclopentadienylacylmolybdenum (1970) (16)
- Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9. (2015) (16)
- Comparison of cytochrome P450 2C subfamily members in terms of drug oxidation rates and substrate inhibition. (2012) (16)
- Determination of the rates of synthesis and degradation of adenosine 3',5'-cyclic monophosphate in Escherichia coli CRP- and CRP+ strains. (1978) (16)
- Measurement of local solids concentration in a suspension by an optical method (1992) (16)
- A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities. (1998) (16)
- Marmoset cytochrome P450 4A11, a novel arachidonic acid and lauric acid ω-hydroxylase expressed in liver and kidney tissues (2017) (16)
- Use of a hydrophobic cloth for enzyme immunoassay (1989) (16)
- Rhodium carbonyl-catalyzed carbonylation of unsaturated compounds: III. Synthesis of α,β-unsaturated ethyl ketones by cross-hydrocarbonylation of acetylenes and ethylene with carbon monoxide and hydrogen (1987) (16)
- Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. (2017) (16)
- Missense and nonsense mutations of the flavin-containing monooxygenase 3 gene in a Japanese cohort. (2007) (16)
- Polymerization of Propylene by Nonbridged Zirconocene Complexes (1998) (16)
- Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver (2019) (16)
- Steady-State Human Pharmacokinetics of Monobutyl Phthalate Predicted by Physiologically Based Pharmacokinetic Modeling Using Single-Dose Data from Humanized-Liver Mice Orally Administered with Dibutyl Phthalate. (2019) (16)
- Comparison of catalytic properties of cytochromes P450 3A4 and 3A5 by molecular docking simulation. (2013) (16)
- Identification and Analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in Cynomolgus Macaques (2014) (16)
- Synthesis and some reactions of n5-pentamethylcyclopentadienylnickel complexes (1979) (16)
- Effect of ketoconazole on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor teneligliptin: an open-label study in healthy white subjects in Germany. (2014) (15)
- Advances in Brief Pretreatment with 8-Methoxypsoralen , a Potent Human CYP 2 A 6 Inhibitor , Strongly Inhibits Lung Tumorigenesis Induced by 4-( Methylnitrosamino )-1-( 3-Pyridyl )-1-Butanone in Female A / J Mice (2003) (15)
- The crystal structure and electronic properties of the Bis(1,3-dimethyl-5-diazophenyl-6-amino uracilato) copper(II) complex, dimethyl sulfoxide solvate - a new pseudotetrahedral CuN4 complex (1990) (15)
- Involvement of human cytochrome P450 2B6 in the ω- and 4-hydroxylation of the anesthetic agent propofol (2007) (15)
- Complex mechanism underlying transcriptional control of the haplotyped flavin-containing monooxygenase 3 (FMO3) gene in Japanese: different regulation between mutations in 5'-upstream distal region and common element in proximal region. (2008) (15)
- Metabolism of P450 probe substrates by cynomolgus monkey CYP2C76. (2011) (15)
- A taxonomical revision of Castanopsis cuspidata (Thunb.) Schottky and the allies in Japan and Taiwan (1) (1987) (15)
- Synthesis and reactivities of the indenyl-ruthenium cluster [(η5-C9H7)Ru(μ-SEt)]3: indenyl effect in the trinuclear ruthenium cluster (1998) (15)
- ELECTROCHEMICAL PREPARATION OF ISOCYANIDE COMPLEXES OF LOW-VALENT PLATINUM CONTAINING A METAL–METAL BOND (1985) (15)
- Prediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in Animals (2018) (15)
- Measurement of growth of bifidobacteria on inulofructosaccharides (1990) (15)
- Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers (2016) (15)
- Pharmacokinetic investigation of increased efficacy against malignant gliomas of carboplatin combined with hyperbaric oxygenation. (2009) (15)
- Natural flavors produced by biotechnical processing (1989) (15)
- Characterization of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene (2000) (15)
- Hexaruthenium carbido carbonyl methyl cluster [PPN][Ru6C(CO)16(CH3)] as catalyst precursor for hydrogenation of olefins. Syntheses and structures of unsaturated and saturated hexaruthenium hydrido clusters [PPN][Ru6C(CO)15H] and [PPN][Ru6C(CO)16H] (1994) (15)
- CYP2G2, Pseudogenized in Human, Is Expressed in Nasal Mucosa of Cynomolgus Monkey and Encodes a Functional Drug-Metabolizing Enzyme (2011) (15)
- Crystal structure of a silver salt of the antibiotic lasalocid A: a dimer having an exact 2-fold symmetry (1989) (14)
- Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys (2014) (14)
- Chemistry of hexaruthenium carbidocarbonyl cluster complexes. Syntheses and X-ray crystal structures of Ru6C(CO)15(μ-SePh)(μ-AuPPh3), Ru6C(CO)14(μ-SePh)2, and Ru6C(CO)14(μ-SePh)(μ,η3-C3H5) (1992) (14)
- Novel regioselection in insertion of a 1,4-disubstituted-1,3-enyne into ruthenium–hydrogen bonds (1991) (14)
- Five Co-ordination in Isocyanide Insertion Complexes of Pd(II) (1970) (14)
- Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes. (2015) (14)
- Distribution, metabolism and excretion of N-nitrosobis(2-hydroxypropyl)amine in Wistar rats. (1984) (14)
- Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine (2016) (14)
- Reaction of a diphenylacetylenecobalt complex with alkyl diazoacetates (1978) (14)
- Synthesis of macrocyclic ketoesters by an n + 1 strategy based on free-radical carbonylation (1997) (14)
- Diiodo-π-cyclopentadienyliridium and Its Derivatives (1971) (14)
- Metal ion interactions with vitamin B1. Crystal structures of Zn(thiamine)(SCN)3 having a metal-base bond and Cd(thiamine)(SCN)3 having a metal-hydroxyethyl bond (1991) (14)
- Drug interactions of diclofenac and its oxidative metabolite with human liver microsomal cytochrome P450 1A2-dependent drug oxidation (2014) (14)
- Use of inexpensive O antisera as the detecting antibodies for Salmonella antigens in the polymyxin-cloth enzyme immunoassay. (1993) (14)
- Reaction of Cobaltocene with Organic Compounds under an Oxygen Atmosphere: A new Route to π-Cyclopentadienyl-(1-exo-organylcyclopentadiene)cobalt (1970) (14)
- Human plasma concentrations of five cytochrome P450 probes extrapolated from pharmacokinetics in dogs and minipigs using physiologically based pharmacokinetic modeling (2016) (14)
- Structural determination of a trinuclear iron-cobalt mixed cluster complex bicapped with sulfur (1988) (14)
- Studies on the interaction of isocyanides with transition metal complexes: XXVII. Preparation of zerovalent isocyanide complexes of chromium, molybdenum and tungsten. The crystal structure of hexakis(2,6-xylyl isocyanide)molybdenum containing benzene as a solvated molecule☆ (1985) (13)
- Construction of an Escherichia coli strain which excretes abnormally large amounts of adenosine 3',5'-cyclic monophosphate. (1978) (13)
- Chemistry of Mixed Transition-metal Complexes. V. The Preparation of Several Mixed Transition-metal Complexes with Two μ-Diphenylphosphido Groups (1973) (13)
- Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine (2018) (13)
- Activation of toxic chemicals by cytochrome P450 enzymes: regio- and stereoselective oxidation of aflatoxin B1. (1996) (13)
- Organic synthesis by low-valent isocyanide complexes. Part 5. Formation of indolenine derivatives from dicobalt octaisocyanide and carbon polyhalide (1988) (13)
- Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants (2018) (13)
- Extraction of Salmonella antigens in non-sedimentable forms for enzyme immunoassay. (1989) (13)
- RHODIUM CARBONYL-CATALYZED CARBONYLATION OF ACETYLENES IN THE PRESENCE OF OLEFINS AND PROTON DONORS. SYNTHESIS OF 5-ALKYL-2(5H)-FURANONES (1981) (13)
- Structure of the orthorhombic form of the barium salt of lasalocid A (1989) (13)
- Low-valent isocyanide complexes and clusters of palladium and platinum. Crystal structure of [Pt{C(NR)N(R)C(NR}(RNC)2](R = 2,6-Me2C6H3) (1989) (13)
- The preparation and chemistry of a zerovalent cobalt(0) complex containing only isocyanide ligands (1977) (13)
- Wavelength-dependent photochemical reaction of methylrhodium(III) octaethylporphyrin. Studies on methyl-rhodium (CH3-Rh) bond cleavage (1985) (13)
- Interligand interactions affecting specific metal bonding to nucleic acid bases: X-ray crystal structure of tetrakis-µ-acetamidatobis(theophylline)rhodium(II)-rhodium(III) nitrate monohydrate (1986) (13)
- Cobalt metallacycles. Part 9. Some reactions of cobaltaindene, cobaltafluorene, cobaltaxanthen, and cobaltacyclopentane complexes (1980) (13)
- Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure (2018) (13)
- Discovery of genetic variants in CYP1D1: implication for functional integrity of CYP1D1 in cynomolgus macaques and rhesus macaques. (2011) (13)
- Immobilization of invertase on polyethylenimine-coated cotton cloth (1984) (13)
- Identification of catalase in human livers as a factor that enhances phenytoin dihydroxy metabolite formation by human liver microsomes. (2002) (12)
- Activation of carcinogenic N-nitrosopropylamines to mutagens by lung and pancreas S9 fractions from various animal species and man. (1986) (12)
- CYP2C76 non-synonymous variants in cynomolgus and rhesus macaques. (2012) (12)
- Compositional Dependence of Fluorescence Spectra of Cr3+/Cr4+-Doped Calcium Alumino-Silicate Glasses for Broadband Telecommunication (2005) (12)
- The dependence of Escherichia coli asparaginase II formation on cyclic AMP and cyclic AMP receptor protein. (1978) (12)
- Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450. (1994) (12)
- Induction of human cytochrome P450 3A enzymes in cultured placental cells by thalidomide and relevance to bioactivation and toxicity. (2017) (12)
- Reaction of (dioxygen)(dithiocarbamato)rhodium complexes with carbon dioxide. Formation and chemical cleavage of rhodium peroxycarbonato and carbonato rings (1990) (12)
- Molecular Cloning, Tissue Distribution, and Functional Characterization of Marmoset Cytochrome P450 1A1, 1A2, and 1B1 (2016) (12)
- Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine (2015) (12)
- Use of detergents in the preparation of Salmonella samples for enzyme immunoassay on polymyxin-coated polyester cloth. (1990) (12)
- The reaction of elemental sulfur with Rh(η5-C5H4Z)(PPh3)2 (Z=H, CO2Me). Formation of RhS4, RhS5, RhS6, and (RhS2)2 catenated metallacycle complexes (1989) (12)
- Role of unsaturated groups in glow discharge polymerization (1984) (12)
- Effect of electron-withdrawing substituents on the cobalt(I)-coordinated cyclopentadienyl ring. Spectra and diene substitution kinetics of [Co(C5H4X)(1,5-cyclooctadiene)] (1987) (12)
- A n + 1 Strategy for Macrocyclization Based on Free-Radical Carbonylation (1994) (12)
- Preparation of hydrophobic cotton cloth (1984) (12)
- X-ray studies on metal ion interactions with vitamins II. Crystal structures of three copper(II) and nickel(II) complexes of Schiff bases formed between 1-aminocyclopropanecarboxylic acid and pyridoxal or pyridoxal 5′-phosphate (1991) (12)
- Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline (2013) (12)
- Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents. (2017) (12)
- Crystal structures of two polymorphic thallium(I) salts of the antibiotic lasalocid A: a polymeric form involving metal-phenyl .pi.-bonding and a monomeric form involving the half-naked metal ion (1992) (12)
- Use of polyvinyl alcohol as a stabilizer of peroxidase-antibody conjugate for enzyme immunoassay (1994) (12)
- Cytochrome P450 2A6 and other human P450 enzymes in the oxidation of flavone and flavanone (2019) (12)
- Functional and molecular characterization of UDP‐glucuronosyltransferase 2 family in cynomolgus macaques (2019) (11)
- Fluvoxamine by itself has potential to directly induce long QT syndrome at supra-therapeutic concentrations. (2015) (11)
- Pre‐incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide (2016) (11)
- The Reaction Mechanism of Ruthenium-catalyzed Dimerization of t-Butylacetylene to cis-1,4-Di-t-butylbutatriene. Involvement of a Ruthenium-diacetylide Intermediate (1989) (11)
- Effects of cytochrome P450 2D6 and 3A5 genotypes and possible coadministered medicines on the metabolic clearance of antidepressant mirtazapine in Japanese patients. (2015) (11)
- Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase (2015) (11)
- Expression profile of hepatic genes in cynomolgus macaques bred in Cambodia, China, and Indonesia: implications for cytochrome P450 genes. (2012) (11)
- Linkage between the distribution of mutations in the CYP2C18 and CYP2C19 genes in the Japanese and Caucasian. (1998) (11)
- Novel candesartan derivatives as indoleamine 2,3-dioxygenase inhibitors (2012) (11)
- Identification and characterization of CYP2B6 cDNA in cynomolgus macaques (Macaca fascicularis). (2009) (11)
- Polymacron™ Enzyme Immunoassay System for Detection of Escherichia coli O157 Inoculated into Foods †. (1997) (11)
- Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine. (2019) (11)
- Studies on Organotransition Metal Complexes (1987) (11)
- Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19 (2018) (11)
- Novel oxidation of pyridoxal in ternary metal complexes. An X-ray study of the products (1986) (11)
- Synthesis of homo- and heterodinuclear metal complexes with dimethylsilylene bridged unsymmetrical bis(cyclopentadienyl) ligand (2001) (11)
- Preparation of Tricarbonyliron--Carbonyl--Diphenylphosphido-p-Cyclopentadienylnickel (1970) (11)
- Expression and inducibility of cytochrome P450s in human hepatocytes isolated from chimeric mice with humanised livers (2018) (11)
- High Performance Scroll Compressor With Liquid Refrigerant Injection (2002) (11)
- A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin- 3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors. (1998) (11)
- Further studies on the dependence of the barriers for gear slippage on the joint group in bis(9-triptycyl)X type molecules. Bis(9-triptycyl)phosphine, the missing link in the series along the third row of the periodic table (1994) (11)
- Effects of propofol analogs on glucuronidation of propofol, an anesthetic drug, by human liver microsomes. (2007) (11)
- Molecular and Functional Characterization of N-Acetyltransferases NAT1 and NAT2 in Cynomolgus Macaque. (2018) (11)
- Iso-antigens of serum proteins of the chicken. (1969) (11)
- Preparation and structural-bonding characterization of a 50-electron triangular cobalt cluster, [Co(C5H4CO2Me)]3(S)(NtBu), with triply bridging sulfido and imido ligands: singlet-triplet equilibrium in solid and solution states (1988) (11)
- An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals (2021) (11)
- Effects of enzyme sources on midazolam 1'-hydroxylation activity catalyzed by recombinant cytochrome P450 3A4 in combination with NADPH-cytochrome P450 reductase. (2008) (10)
- Species Difference between Cynomolgus Monkeys and Humans on Cytochromes P450 2D and 3A-Dependent Drug Oxidation Activities in Liver Microsomes (2011) (10)
- [Studies on active substances of the herbs used for oketsu, blood coagulation, in Chinese medicine. I. On anticoagulant activities of the herbs used for oketsu]. (1984) (10)
- Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. (2001) (10)
- The Hydroboration of Some Unsaturated Organosilicon Compounds (1963) (10)
- Ternary metal complexes of vitamin B6 related compounds. Crystal and molecular structures of copper(II)–2,2′-bipyridyl-pyridoxic acid and copper(II)–2,2′-bipyridyl–pyridoxic acid γ-lactone complexes (1987) (10)
- Some Stable Sigma-bonded Alkyl Derivatives of Nickel (1964) (10)
- Cynomolgus macaque CYP4 isoforms are functional, metabolizing arachidonic acid. (2011) (10)
- Rapid and economical detection of Salmonella enteritidis in eggs by the polymyxin-cloth enzyme immunoassay. (1995) (10)
- Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes (2019) (10)
- Preparation and some properties of cyclopentadienylcobalt(I)-olefin complexes (1982) (10)
- Production of acetaldehyde from ethanol byCandida utilis (1984) (10)
- In vivo and in vitro diclofenac 5‐hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants (2018) (10)
- Synthesis and structural characterization of triphenyltin halide-lactam complexes (1987) (10)
- Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5. (2019) (10)
- Carbonyldiimidazole activation of a rayon/polyester cloth for covalent immobilization of proteins (1991) (10)
- The Oligomerization and Co-oligomerization of Active Methylene Compounds and Isocyanides Catalyzed by Octaisocyanidedicobalt (1981) (10)
- Bonitos with low content of malodorous trimethylamine as palliative care for self-reported Japanese trimethylaminuria subjects. (2009) (10)
- Human plasma metabolic profiles of benzydamine, a flavin-containing monooxygenase probe substrate, simulated with pharmacokinetic data from control and humanized-liver mice (2018) (10)
- Reactions of cobaltacyclopentadiene complexes with organic azides directed toward synthesis of highly substituted pyrroles (1989) (10)
- Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology. (2017) (10)
- Lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine-related compounds and their formation in rats. (1987) (10)
- Direct genotyping of Cytochrome P450 2A6 whole gene deletion from human blood samples by the SmartAmp method. (2011) (10)
- Metabolism of desloratadine by chimeric TK-NOG mice transplanted with human hepatocytes (2020) (10)
- Rhodium Carbonyl Catalyzed Carbonylation of Unsaturated Compounds. IV. Carbonylation and Oligomerization of Diphenylacetylene Catalyzed by Co4(CO)12, Rh4(CO)12, and Ir4(CO)12 under Pressure of Carbon Monoxide (1990) (10)
- Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets. (2016) (10)
- A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine (2016) (10)
- Catalytic Dimerization of Monoalkyl Acetylenes (1961) (10)
- Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers (2017) (10)
- Human Aldehyde Oxidase 1–Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes (2020) (10)
- Cobalt metallacycles. Part 16. X-Ray structures of 4-iminocobaltacyclobutene complexes (1986) (10)
- CYP2D44 polymorphisms in cynomolgus and rhesus macaques (2015) (10)
- Mannose utilization in Escherichia coli requires cyclic AMP but not an exogenous inducer. (1980) (10)
- Blood Concentrations of 1,4-Dioxane in Humans after Oral Administration Extrapolated from In Vivo Rat Pharmacokinetics, In Vitro Human Metabolism, and Physiologically Based Pharmacokinetic Modeling (2010) (10)
- Studies on the interaction of isocyanide with transition-metal complexes. 15. New type of insertion reactions of isocyanide into alkyliron complexes (1977) (10)
- Four- and five-coordinated nickel(II) isocyanide complexes and donor- acceptor complexes containing nickel and mercury (1991) (10)
- Process Development of a Novel Non-Xanthine Adenosine A1 Receptor Antagonist (1999) (10)
- Hydrosilylation of α-methylstyrene and ketones catalyzed by group 10 and rhodium isocyanide complexes (1989) (10)
- Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes. (2019) (10)
- Film fermentor for ethanol production by yeast immobilized on cotton cloth (1984) (9)
- Stabilization effect of polyvinyl alcohol on horseradish peroxidase, glucose oxidase, β-galactosidase and alkaline phosphatase (1996) (9)
- Investigation of the acidic nature of MCM-68 zeolite based on the adsorption of CO and bulky probe molecules (2018) (9)
- Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry. (2016) (9)
- Selective synthesis of oxygenates in the CO–H2 reaction on supported ruthenium carbido-cluster catalysts (1992) (9)
- Molecular characterization of functional UDP-glucuronosyltransferases 1A, 2B in common marmosets. (2019) (9)
- Crystal structures of an antiallergic 8-azapurine (v-triazolo[4,5-d]pyrimidine) and its metal complex, 3-methyl-8-azaxanthine monohydrate and trans-diamminebis(3-methyl-8-azaxanthinato)copper(II) dihydrate (1986) (9)
- A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction. (1986) (9)
- Rhodium carbonyl-catalyzed carbonylation of unsaturated compounds: V. Cross-hydrocarbonylation of 1-alkyne and ethylen by rhodium carbonyl catalyst modified with phosphines (1991) (9)
- X-Ray crystal structures of the nickel(II) and copper(II) complexes of O-phospho-DL-threonine–pyridoxal Schiff base (1980) (9)
- Preparation of chiral tricarbonyl arene thiol chromium and its application to asymmetric ring opening of meso-epoxides (1997) (9)
- Human cytochrome P450 1A1 is a novel target gene of liver X receptor α. (2011) (9)
- Effect of power consumption on solids concentration profiles in a slurry mixing tank (1991) (9)
- Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes (2018) (9)
- DIRECT SYNTHESIS OF N-ARYL BENZAMIDES BY REDUCTIVE CARBONYLATION OF NITROARENES CATALYZED BY RHODIUM CARBONYLS IN BENZENE (1980) (9)
- Cobalt metallacycles. Part 15. Regioselective formation and rearrangement of 4-iminocobaltacyclobutene complexes (1986) (9)
- Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling (2019) (9)
- Diene derivatives of hexarhodium hexadecacarbonyl. Molecular structures of Rh6(CO)14 (η4-CH2C(Me)C(Me)CH2 and Rh6(CO)12(η4-CH2C(Me)C(Me)CH2)2, and their substitution reactions with bis(diphenylphosphino)methane (1990) (9)
- New Hydrido- and Oxygen-complexes of Rhodium (1968) (9)
- Pharmacokinetics and metabolism of pemafibrate, a novel selective peroxisome proliferator‐activated receptor‐alpha modulator, in rats and monkeys (2019) (9)
- Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non‐smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3 (2016) (9)
- Electrochemical Preparation of Tetrakis(isocyanide)dipalladium(I) Dichloride (1987) (9)
- Hexamethyleneimine and pivalonitrile as location probe molecules of Lewis acid sites on MWW-type zeolites (2015) (9)
- Production of Fructo-Oligosaccharide-Rich Fructose Syrup (1993) (9)
- Molecular and functional characterization of UDP‐glucuronosyltransferase 1A in cynomolgus macaques (2018) (9)
- Human pharmacokinetic profiling of the dipeptidyl peptidase‐IV inhibitor teneligliptin using physiologically based pharmacokinetic modeling (2015) (9)
- Purification of jerusalem artichoke fructans and their utilisation by bifidobacteria (1994) (9)
- In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate Chemicals. (2021) (9)
- Thermal and photochemical oxygenation of cobaltacyclopentadiene complexes with dioxygen (1977) (9)
- A rapid multiplex PCR assay that can reliably discriminate the cytochrome P450 2D6 whole-gene deletion allele from 2D6*10 alleles. (2012) (9)
- Cytochrome P450 reconstitution systems. (2006) (9)
- Half-way coordination state of a butadienyl group on ruthenium. η3-Allylic bonding with η1-character or vice versa (1992) (8)
- Immobilization of Bacteria on to Polyester Cloth (1998) (8)
- Assay of Salmonella in enrichment cultures of foods, feeds and environmental samples by the polymyxin-cloth enzyme immunoassay. (1997) (8)
- Rapid confirmation of polymyxin-cloth enzyme immunoassay for group D salmonellae including Salmonella enteritidis in eggs by polymerase chain reaction (1995) (8)
- R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys (2018) (8)
- Identification and characterization of CYP2C18 in the cynomolgus macaque (Macaca fascicularis). (2010) (8)
- Methyl-hydroxylation and subsequent oxidation to produce carboxylic acid is the major metabolic pathway of tolbutamide in chimeric TK-NOG mice transplanted with human hepatocytes (2021) (8)
- Stereochemical Properties of Copper(II) Complexes of (RS)-3-Aminohexahydroazepine: Crystal and Molecular Structures of [(R)-3-Aminohexahydroazepine][(S)-3-aminohexahydroazepine]copper(II) Diperchlorate, [Cu(R-ahaz)(S-ahaz)](ClO4)2 and Related Complexes (1987) (8)
- Application of cloth-based enzyme immunoassay for the characterization of monoclonal antibodies to Salmonella lipopolysaccharide antigens. (1996) (8)
- Structure of tetrakis(2,6-xylyl isocyanide)rhodium(I) 7,7,8,8-tetracyano-p-quinodimethane, [Rh(2,6-Me2C6H3NC)4]+(TCNQ)− (1984) (8)
- Systematic characterization of glutathione S-transferases in common marmosets. (2020) (8)
- The marmoset cytochrome P450 superfamily: sequence/phylogenetic analyses, genomic structure, and catalytic function. (2019) (8)
- In vivo individual variations in pharmacokinetics of efavirenz in cynomolgus monkeys genotyped for cytochrome P450 2C9. (2016) (8)
- Rapid antibody assay based on initial rate of immunoreaction (1989) (8)
- Zone analysis by two-dimensional electrophoresis with accelerator mass spectrometry of in vivo protein bindings of idiosyncratic hepatotoxicants troglitazone and flutamide bioactivated in chimeric mice with humanized liver (2015) (8)
- A Case of Delayed Emergence After Propofol Anesthesia: Genetic Analysis. (2016) (8)
- Simple assay and extraction of periplasmic penicillinase in Escherichia coli. (1981) (8)
- Intravenous Administration of Apomorphine Does NOT Induce Long QT Syndrome: Experimental Evidence from In Vivo Canine Models (2015) (8)
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- Effect of N-substituents on polymerization reactivity of N-alkylitaconimides in radical polymerization (1997) (8)
- Kinetics and Mechanism of Aquation and Anation of Some Amino Acid Pentamminecobalt(III) Complexes in Acid Aqueous Solutions (1971) (8)
- Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes. (2017) (8)
- Specificity of monoclonal antibodies to Campylobacter jejuni lipopolysaccharide antigens. (1998) (8)
- Preparation of thiolate-bridged diruthenium complexes with Ru-Ru single bond. (1986) (8)
- Molecular and functional characterization of cytosolic sulfotransferases in cynomolgus macaque. (2019) (8)
- Cloning, expression, and characterization of CYP3A43 cDNA in cynomolgus macaque (Macaca fascicularis). (2009) (8)
- Intravenous and oral administrations of DD2 [7-Amino-2-(sulfanylmethyl)heptanoic acid] produce thrombolysis through inhibition of plasma TAFIa in rats with tissue factor-induced microthrombosis. (2012) (8)
- A newly developed DNA microarray is useful to assess induction of cytochromes p450 in the cynomolgus monkey. (2011) (8)
- Improved Intranasal Retentivity and Transnasal Absorption Enhancement by PEGylated Poly-l-ornithine (2018) (8)
- In vivo Analysis of the Anti-atrial Fibrillatory, Proarrhythmic and Cardiodepressive Profiles of Dronedarone as a Guide for Safety Pharmacological Evaluation of Antiarrhythmic Drugs (2018) (8)
- Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase (2017) (8)
- Human liver enzymes responsible for metabolic elimination of tyramine; a vasopressor agent from daily food. (2011) (8)
- Ratio of serum levels of AGEs to soluble RAGE is correlated with trimethylamine-N-oxide in non-diabetic subjects (2017) (8)
- Effects of histidine-tag on recombinant human cytochrome P450 3A5 catalytic activity in reconstitution systems. (2009) (8)
- Whither the impending european regulation of presumed endocrine disruptors? (2016) (8)
- Stability of polypeptide immunoreactants and polyvinyl alcohol as a blocking agent on polyester cloth during dry storage. (1995) (8)
- Analysis of six novel flavin-containing monooxygenase 3 (FMO3) gene variants found in a Japanese population suffering from trimethylaminuria (2015) (8)
- Mercury and platinum mixed cluster having a prismatic structure, [HgPt6(2,6-Me2C6H3NC)12] (1994) (8)
- Novel variants and haplotypes of human flavin-containing monooxygenase 3 gene associated with Japanese subjects suffering from trimethylaminuria (2018) (8)
- Carbon monoxide-breathing ruthenium carbido clusters on magnesium oxide (MgO) in CO/H2 reaction conditions (1993) (8)
- Effect of carbon sources on the rates of cyclic AMP synthesis, excretion, and degradation, and the ability to produce beta-galactosidase in Escherichia coli. (1979) (8)
- Association of pharmacokinetic profiles of lenalidomide in human plasma simulated using pharmacokinetic data in humanized-liver mice with liver toxicity detected by human serum albumin RNA. (2018) (8)
- Trimethylamine generation in patients receiving hemodialysis treated with l-carnitine (2014) (7)
- Cytochrome P450 1A1, 2C9, 2C19, and 3A4 Polymorphisms Account for Interindividual Variability of Toxicological Drug Metabolism in Cynomolgus Macaques. (2018) (7)
- The effective silylation of external surface on H-ZSM5 with cyclic siloxane for the catalytic cracking of naphtha (2017) (7)
- Stabilization of peroxidase-antibody conjugate in solution by polyethylene oxide (1993) (7)
- Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays. (2015) (7)
- Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model (2018) (7)
- Genetic Variants of Glutathione S-Transferase GSTT1 and GSTT2 in Cynomolgus Macaques: Identification of GSTT Substrates and Functionally Relevant Alleles. (2018) (7)
- High-performance liquid chromatographic assay for carboplatin in ultrafiltered plasma combined with hyperbaric oxygenation. (2006) (7)
- Novel nonsynonymous polymorphisms of the CYP1A1 gene in Japanese. (2003) (7)
- Restriction enzyme digestion analysis of PCR-amplified DNA of Blastocystis hominis isolates. (2007) (7)
- Stability of a Dispersed Phase Chemical Reactor and Effect of Coalescence and Redispersion of Dispersed Drops (1970) (7)
- Cobalt metallacycles. Part 14. Facile transformation of η4-diene complexes to metallacyclopentenes. Preparation and molecular structures of [Co(η5-C5H5){η4-PhNCC(Ph)C(Ph)CNPh}] and [Co{C(NR)C(Ph)C(Ph)C(NR)}(η5-C5H5)(CNC6H3Me2-2,6)](R = C6H3Me2-2,6) (1986) (7)
- Highly sensitive HPLC assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes (1999) (7)
- Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models (2018) (7)
- Intramolecular H/D Exchange of Ethanol Catalyzed by Acidic OH Groups on H-ZSM-5 Zeolite. (2014) (7)
- Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital (2021) (7)
- Development of a genotyping tool for a functionally relevant CYP2C19 allele (Phe100Asn, Ala103Val and Ile112Leu) in cynomolgus macaques (2015) (7)
- Suitable albumin concentrations for enhanced drug oxidation activities mediated by human liver microsomal cytochrome P450 2C9 and other forms predicted with unbound fractions and partition/distribution coefficients of model substrates (2018) (7)
- Human urinary concentrations of monoisononyl phthalate estimated using physiologically based pharmacokinetic modeling and experimental pharmacokinetics in humanized-liver mice orally administered with diisononyl phthalate (2019) (7)
- 37. Propylene Polymerizations with Silylene-Bridged Metallocene Catalysts (1990) (7)
- Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database. (2019) (7)
- Ethene oligomerization on H-ZSM-5 in relation to ethoxy species (2014) (7)
- Increased plasma concentrations of an antidyslipidemic drug pemafibrate co-administered with rifampicin or cyclosporine A in cynomolgus monkeys genotyped for the organic anion transporting polypeptide 1B1. (2020) (7)
- Similar substrate specificity of cynomolgus monkey cytochrome P450 2C19 to reported human P450 2C counterpart enzymes by evaluation of 89 drug clearances (2015) (7)
- Tosyl chloride activation of a rayon/polyester cloth for protein immobilization (1993) (7)
- Formation of a cobaltacyclopentene complex by the reaction of 2-ethynylpyridine with [Co(η5-C5H5)(PPh3)2] (1989) (7)
- X-Ray crystal structure of a Schiff's base complex of copper(II) (1984) (7)
- Aliphatic amino acid-metal ion-aromatic amine ternary complexes. Crystal structures of aqua(L-leucinato)(1,10-phenanthroline)copper(II) nitrate and aqua(DL-leucinato)(1,10-phenanthroline)copper(II) nitrate (1989) (7)
- Expression of cytochromes p450 in fetal, infant, and juvenile liver of cynomolgus macaques. (2011) (7)
- New Type Acetylene Compexes with Mixed Transition Metals (1969) (7)
- Simple pharmacokinetic models accounting for drug monitoring results of atomoxetine and its 4-hydroxylated metabolites in Japanese pediatric patients genotyped for cytochrome P450 2D6. (2019) (7)
- Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes. (1990) (7)
- Upholding science in health, safety and environmental risk assessments and regulations. (2016) (7)
- Isolation, structure and iridium-mediated decarbonylation of a sodium fluorenone dianion complex (1998) (7)
- Absorption and circular dichroism studies of rhodium(I) complexes containing chiral isocyanides (1982) (6)
- Influence of microsomal and cytosolic fractions from the liver of 4 animal species and man on the mutagenicity of carcinogenic aminoazo dyes and nature of the mutagenicity-enhancing factor in the cytosol from rat liver. (1984) (6)
- Cytochrome P450-dependent drug oxidation activities in commercially available hepatocytes derived from human induced pluripotent stem cells cultured for 3 weeks. (2018) (6)
- Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase (2017) (6)
- Use of hydrophobic cloths as antibody adsorbents for enzyme immunoassay: detection of Brucella antigens. (1989) (6)
- SYNTHESIS OF γ-KETOPIMELIC ACID DERIVATIVES BY RHODIUM CARBONYL-CATALYZED HYDROCARBONYLATION OF ACRYLIC ACID DERIVATIVES (1982) (6)
- Different metabolites of human hepatotoxic pyrazolopyrimidine derivative 5-n-butyl-pyrazolo[1,5-a]pyrimidine produced by human, rat and monkey cytochrome P450 1A2 and liver microsomes. (2012) (6)
- Predicted Contributions of Flavin-containing Monooxygenases to the NOxygenation of Drug Candidates Based on their Estimated Base Dissociation Constants. (2020) (6)
- Zn(II) and Hg(II) complexes of 4,6-diamino-2-thiopyrimidine and 4,6-diamino-2-methylthiopyrimidine. Crystal structure of 4,6-diamino-2-methylthiopyrimidinium hemitetrachlorozincate(II) (1990) (6)
- Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies (2018) (6)
- Different Effects of TERT, TP63, and CYP2A6 Polymorphism on Individual Risk of Tobacco-Related Lung Cancer in Male Japanese Smokers (2011) (6)
- Characterization of an Escherichia coli mutant which utilizes glycerol in the absence of cyclic adenosine monophosphate. (1980) (6)
- Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes. (1998) (6)
- RHODIUM CARBONYL-CATALYZED CARBONYLATION OF ACETYLENES IN ALCOHOL. SYNTHESIS OF 5-ALKOXY-2(5H)-FURANONES (1981) (6)
- Reactions of cyclobutenedione and cyclopentenetrione with zero-valent nickel triad complexes of isocyanide. X-Ray crystal structures of (3–4-η-3,4-diphenylcyclobut-3-ene-1,2-dione)- and (4–5-η-4,5-diphenylcyclopent-4-ene-1,2,3-trione)-tris(t-butyl isocyanide)nickel (1987) (6)
- Electrode reaction mechanisms of platinum isocyanide complexes in acetonitrile solutions (1988) (6)
- Genotyping of wild-type cytochrome P450 2A6 and whole-gene deletion using human blood samples and a multiplex real-time polymerase chain reaction method with dual-labeled probes. (2015) (6)
- Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets (2016) (6)
- A NOVEL HIGH NUCLEARITY PLATINUM ISOCYANIDE CLUSTER (1979) (6)
- Structures of thiamine hexafluorophosphate monohydrate, thiaminium diperchlorate, thiaminium bis(hexafluorophosphate) tetrahydrate, andthiaminemonophosphate hexafluorophosphate dihydrate (1988) (6)
- Comparison of the Contributions of Cytochromes P450 3A4 and 3A5 in Drug Oxidation Rates and Substrate Inhibition (2010) (6)
- Clinical evidence of pharmacokinetic changes in thalidomide therapy. (2013) (6)
- Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital (2020) (6)
- Crystal structure of the 1-aminocyclopropanecarboxylate–pyridoxal Schiff base complex of copper(II): a model for a Schiff base intermediate in ethylene biosynthesis (1987) (6)
- Metabolic activation and deactivation of dietary-derived coumarin mediated by cytochrome P450 enzymes in rat and human liver preparations. (2021) (6)
- Effects of high levels of selenite and Escherichia coli on enrichment of Salmonella and detection of Salmonella by polymyxin-cloth enzyme immunoassay. (1995) (6)
- Structures of thiamine thiocyanate, thiamine thiocyanate monohydrate and thiamine tetrafluoroborate monohydrate (1990) (6)
- Development of High Performance R410A Scroll Compressor for Gas Engine Heat Pump (2004) (6)
- Significance of β-galactosidase repression in glucose inhibition of lactose utilization inEscherichia coli (1982) (6)
- Effects of ADH1C, ALDH2, and CYP2A6 Polymorphisms on Individual Risk of Tobacco-Related Lung Cancer in (2013) (6)
- A simple and inexpensive glucose oxidase substrate system for enzyme immunoassay. (1992) (6)
- Preference for O-demethylation reactions in the oxidation of 2′-, 3′-, and 4′-methoxyflavones by human cytochrome P450 enzymes (2020) (6)
- Monolayer Tantalum Oxide on Mesoporous Silica Substrate (2016) (6)
- Cyclopentadienyl- and Pentamethylcyclopentadienylbis(isocyanide)cobalt(I) (1978) (6)
- New Five-coordinate Iridium Complexes (1969) (6)
- Cobalt metallocycles. Part 10. Preparation and X-ray structures of two isomeric dicyanocobaltacyclopentanes (1982) (6)
- Activities of cytochrome p450 enzymes in liver and kidney microsomes from systemic carnitine deficiency mice with a gene mutation of carnitine/organic cation transporter. (2002) (6)
- Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes (2018) (6)
- Cytochrome P450-dependent drug oxidation activities and their expression levels in liver microsomes of chimeric TK-NOG mice with humanized livers. (2022) (6)
- Stabilization of polyvinyl alcohol coating of polyester cloth for reduction of bacterial adhesion (1999) (6)
- Immunological detection of adulteration of ground meats by meats of other origins (1997) (6)
- Stable and episodic/bolus patterns of methylmercury exposure on mercury accumulation and histopathologic alterations in the nervous system (2017) (6)
- Predicting successful/unsuccessful extrapolation for in vivo total clearance of model compounds with a variety of hepatic intrinsic metabolism and protein bindings in humans from pharmacokinetic data using chimeric mice with humanised liver (2020) (6)
- Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6 (2019) (6)
- ROLES OF CYTOCHROMES P 450 1 A 2 , 2 A 6 , AND 2 C 8 IN 5-FLUOROURACIL FORMATION FROM TEGAFUR , AN ANTICANCER PRODRUG , IN HUMAN LIVER MICROSOMES (2000) (6)
- Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment (2020) (5)
- Rhodium carbonyl-catalyzed activation of carbon-hydrogen bonds for application in organic synthesis. VI. The reaction of substituted benzenes with methyl acrylate in the presence of dodecacarbonyltetrarhodium. (1985) (5)
- Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from in vivo Animal Pharmacokinetics Using in vitro Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies (2015) (5)
- Efavirenz clearances in vitro and in vivo in six cynomolgus monkeys associated with polymorphic cytochrome P450 2C9 and simulated by individual physiologically based pharmacokinetic models (2017) (5)
- Species differences in hydrolase activities toward OT-7100 responsible for different bioavailability in rats, dogs, monkeys and humans (2006) (5)
- Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital (2021) (5)
- Metallacyclobutene formation from a substituted-acetylene complex of cobalt and an isocyanide. Regioselectivity and rearrangement (1985) (5)
- Roles of human cytochrome P450 1A2 in coumarin 3,4-epoxidation mediated by untreated hepatocytes and by those metabolically inactivated with furafylline in previously transplanted chimeric mice. (2021) (5)
- Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans. (2021) (5)
- A Dicobaltplatinum Complex and its Platinum Precursor (2007) (5)
- Oxidative metabolism and pharmacokinetics of the EGFR inhibitor BIBX1382 in chimeric NOG-TKm30 mice transplanted with human hepatocytes. (2021) (5)
- Studies of the interaction of isocyanides with transition-metal complexes. XXVI: The preparation of octakis(aryl isocyanide)dirhodium (1984) (5)
- Stimulation of Cytochrome P450 Reactions by Apo-cytochromeb 5 (2001) (5)
- Human plasma and liver concentrations of styrene estimated by combining a simple physiologically based pharmacokinetic model with rodent data. (2019) (5)
- Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques. (2020) (5)
- Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals. (2007) (5)
- Modes of inhibition of foodborne non-Salmonella bacteria by selenite cystine selective broth. (1994) (5)
- Synthesis of a hydrido octaruthenium cluster: X-ray analysis of [H2Ru8(CO)21]2– (1988) (5)
- Human plasma and urinary metabolic profiles of trimethylamine and trimethylamine N-oxide extrapolated using a simple physiologically based pharmacokinetic model. (2017) (5)
- Novel N-[1-(1-substituted 4-piperidinylmethyl)-4-piperidinyl]benzamides as potent colonic prokinetic agents. (2002) (5)
- Molecular and functional characterization of flavin-containing monooxygenases in pigs, dogs, and cats. (2022) (5)
- Human plasma concentrations of trimethylamine N-oxide extrapolated using pharmacokinetic modeling based on metabolic profiles of deuterium-labeled trimethylamine in humanized-liver mice. (2018) (5)
- Individual differences in in vitro and in vivo metabolic clearances of antipsychotic risperidone from Japanese subjects genotyped for cytochrome P450 2D6 and 3A5 (2016) (5)
- Activities of rat cytochrome P450 3A and 2C isoforms are increased in vivo by magnesium sulfate as evidenced by enhanced oxidation of bupivacaine and testosterone in liver microsomes. (2006) (5)
- A liquid medium for growth of the thermophilic campylobacters in a carbon dioxide air mixture as studied by polymyxin-cloth enzyme immunoassay☆ (1998) (5)
- Functionally relevant genetic variants of glutathione S-transferase GSTM5 in cynomolgus and rhesus macaques (2018) (5)
- Structure − Function Studies of Naphthalene , Phenanthrene , Biphenyl , and Their Derivatives in Interaction with and Oxidation by Cytochromes P 450 2 A 13 and 2 A 6 (2016) (5)
- Dataset for genotyping validation of cytochrome P450 2A6 whole-gene deletion (CYP2A6*4) by real-time polymerase chain reaction platforms (2015) (5)
- Development of Emissions Factor for the Decentralized Domestic Wastewater Treatment for the National Greenhouse Gas Inventory (2014) (5)
- Syntheses and crystal structures of the ruthenium carbidocarbonyl clusters [Ru5C(CO)11(µ-Br)2(η3-C3H5)(µ-η3-C3H5)], [Ru5C(CO)13I(µ-I)(µ-η2-COMe)]–, [Ru5C(CO)14(µ-Br)2] and [Ru6C(CO)16(µ-Br)]– with novel metal frameworks (1995) (5)
- Analysis of gene expression for microminipig liver transcriptomes using parallel long‐read technology and short‐read sequencing (2016) (5)
- Adsorption of Saccharomyces cerevisiae onto cellulose and ECTEOLA-cellulose films for ethanol production (1983) (5)
- Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates (2018) (5)
- Non-synonymous genetic variants of flavin-containing monooxygenase 3 (FMO3) in cynomolgus macaques. (2019) (5)
- Transparent Cr4+-doped gehlenite (Ca2Al2SiO7) glass-ceramics for broadband amplifier (2003) (5)
- Stability of plasmid PBR322 in Escherichia coli immobilized on cotton cloth during use as resident inoculum (1987) (5)
- Metabolic Profiles of Tetrabromobisphenol A in Humans Extrapolated from Humanized-Liver Mouse Data Using a Simplified Physiologically Based Pharmacokinetic Model. (2020) (5)
- Novel High Performance ansa-Zirconocene Catalysts for Isospecific Polymerization of Propylene (1999) (4)
- Cytochrome P450 2A6 Phenotyping Using Dietary Caffeine Salivary Metabolite Ratios and Genotyping Using Blood on Storage Cards in Non-smoking Japanese Volunteers. (2017) (4)
- Aryl Hydrocarbon Hydroxylase Represents CYP1B1, and not CYP1A1, in Human Freshly Isolated White Cells (2003) (4)
- Development of Nitrogen Gas Bubbling Deaerator Made of Polyvinyliden Fluoride (1995) (4)
- Aflatoxin B1 oxidation by human cytochrome P450s. (1998) (4)
- Synthesis of optically active af-(1-Ethyl-3-methylhexahydro-1,3-diazin-5-yl)- and N-(1-Ethyl-5-methyloctahydro-1,5-diazocin-3-yl)pyridine-3-carboxamides (2002) (4)
- Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning. (2021) (4)
- Point mutation of cytochrome P450 2A6 (a polymorphic variant CYP2A6.25) confers new substrate specificity towards flavonoids (2015) (4)
- Synthesis and properties of BiScO3–PbTiO3 powders and thin films using metal-organic precursor solutions (2010) (4)
- [Roles of human cytochrome P450 enzymes involved in drug metabolism and toxicological studies]. (2001) (4)
- Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liver (2019) (4)
- Metabolic profiles of coumarin in human plasma extrapolated from a rat data set with a simplified physiologically based pharmacokinetic model. (2020) (4)
- Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital (2021) (4)
- Feasibility of physiologically based pharmacokinetic simulations for assessing pediatric patients after accidental drug ingestion: A case study of a 1.4-year-old girl who ingested alprazolam. (2021) (4)
- Pharmacokinetics and Drug Metabolism Expression of functional sulfotransferases (SULT) 1A1, 1A3, 1B1, 1C2, 1E1, and 2A1 in common marmosets. (2020) (4)
- Novel mutations of the CYP2A6 gene in a Thai population with lowered capacity of coumarin 7-hydroxylation. (2002) (4)
- Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver (2011) (4)
- Mechanisms of reactions of methoxy species with benzene and cyclohexane over H-ZSM-5 zeolites (2015) (4)
- Effect of Genetic Polymorphism of CYP2A6 on Individual Susceptibility to Colorectal Tumors in Japanese Smokers (2012) (4)
- Axially dissymmetric 2,2′-diisocyano-1,1′-binaphthyl and its platinum complexes (1986) (4)
- In vivo drug interactions of itopride and trimethylamine mediated by flavin-containing monooxygenase 3 in humanized-liver mice. (2020) (4)
- Different roles of human cytochrome P450 2C9 and 3A enzymes in diclofenac 4'- and 5-hydroxylations mediated by metabolically inactivated human hepatocytes in previously transplanted chimeric mice. (2019) (4)
- Selective carbonyl insertion and ethene hydroformylation on a [Ru6C(CO)16Me]––SiO2 catalyst (1993) (4)
- Methylruthenium carbidocarbonyl clusters supported on inorganic oxides: characterization and selective acetaldehyde formation (1992) (4)
- A major genotype in UDP-glucuronosyltransferase 2B15. (2002) (4)
- A novel procedure for the recovery of hybrid products from protoplast fusion (1982) (4)
- Genotoxic Activation of the Environmental Pollutant 3-Nitrobenzanthrone by Human Cytochrome P450 Enzymes Expressed in Salmonella typhimurium umu Tester Strains (2007) (4)
- Identification of the Basic Sites on Nitrogen-Substituted Microporous and Mesoporous Silicate Frameworks Using CO2 as a Probe Molecule. (2018) (4)
- Dihydrocodeine Overdoses in a Neonate and in a 14-year-old Girl Who Were Both Genotyped as Cytochrome P450 2D6*1/*10-*36: Comparing Developmental Ages and Drug Monitoring Data With the Results of Pharmacokinetic Modeling. (2018) (4)
- In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions (2018) (4)
- Marmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver (2019) (4)
- Increased transendothelial permeability of anti-cancer agent carboplatin with the aid of hyperbaric oxygenation (2008) (4)
- Extracellular accumulation of L-glutamate in adenylyl cyclase deficient or cyclic AMP receptor protein deficient mutants of Escherichia coli. (1980) (4)
- Plasma and hepatic concentrations of acetaminophen and its primary conjugates after oral administrations determined in experimental animals and humans and extrapolated by pharmacokinetic modeling (2020) (4)
- Metabolic Activation of Chrysene by Human Hepatic and Pulmonary Cytochrome P450 Enzymes (1996) (4)
- Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig. (2011) (4)
- Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential. (2020) (4)
- Synthesis and Redox Property of Cyclic Mixed-Metal Complexes from Diethynylbiferrocene (2001) (4)
- Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines (2018) (4)
- Impact of nitrogen compound variability of sewage treated water on N2O production in riverbeds. (2021) (4)
- Mutagenicity of N-nitrosodiethanolamine in the Salmonella/microsome test. (1987) (4)
- Al ion-exchanged USY in FCC catalyst for high LPG yield (2021) (4)
- Bidentate isocyanides 1. Synthesis of disocyanocyclohexanes and some of their complexes (1981) (4)
- Isocyanide complexes with Pt2S and Pt2CS cores. Crystal structure of µ-sulphido-bis[bis(2,4,6-tri-t-butylphenyl isocyanide)platinum] (1986) (4)
- CYP1B1 is polymorphic in cynomolgus and rhesus macaques. (2011) (4)
- Teicoplanin physiologically based pharmacokinetic modeling offers a quantitative assessment of a theoretical influence of serum albumin and renal function on its disposition (2021) (4)
- Metabolic profiles for the pyrrolizidine alkaloid neopetasitenine and its metabolite petasitenine in humans extrapolated from rat in vivo and in vitro data sets using a simplified physiologically based pharmacokinetic model. (2021) (4)
- An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Concentrations after Oral Doses in Rats. (2021) (4)
- Machine Learning Prediction of the Three Main Input Parameters of a Simplified Physiologically Based Pharmacokinetic Model Subsequently Used to Generate Time-Dependent Plasma Concentration Data in Humans after Oral Doses of 212 Disparate Chemicals. (2021) (4)
- Highly Diastereoselective Reduction of Chiral (Ferrocenylseleno)methyl Aryl and Alkyl Ketones. (1999) (4)
- In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys and humans (2018) (4)
- Drug Interaction Studies in the 21st Century: Research into Cytochrome P450s, Transporters, and Simulations Informing Their Role in Drug-drug Interactions (2007) (3)
- RHODIUM CARBONYL-CATALYZED CROSS-HYDROCARBONYLATION OF ACETYLENES AND ETHYLENE. SYNTHESIS OF α,β-UNSATURATED KETONES (1982) (3)
- Crystal Structure of the Complex Formed by the Reaction of an Alkynyl(hydrido)ruthenium(II) with Butadiene. (1993) (3)
- Functional characterization and tissue expression of marmoset cytochrome P450 2E1 (2017) (3)
- Preparation and reactions of chloro-tris(2,6-xylyl isocyanide)-rhodium (1977) (3)
- Development Status of a Planer Type of 1 kW Class SOFC System (2007) (3)
- Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009). (1992) (3)
- Cloning and expression of a novel catechol-O-methyltransferase in common marmosets (2016) (3)
- Elucidation of the Mechanism of Blockage in Sewer Pipes by Fatty Acid Deposition and Suspended Solid (2020) (3)
- Development of genotyping method for functionally relevant variants of cytochromes P450 in cynomolgus macaques. (2018) (3)
- A series of simple detection systems for genetic variants of flavin-containing monooxygenase 3 (FMO3) with impaired function in Japanese subjects. (2021) (3)
- Molecular structures and bonding of η-cyclopentadienyl(substituted diene)cobalt complexes (1982) (3)
- Pharmacokinetics of anticoagulants apixaban, dabigatran, edoxaban and rivaroxaban in elderly Japanese patients with atrial fibrillation treated in one general hospital (2018) (3)
- Rapid and simple method for detectingSalmonellain chicken feces using polymyxin-cloth enzyme immunoassay (1996) (3)
- Systematic approach to optimize a pretreatment method for ultrasensitive liquid chromatography with tandem mass spectrometry analysis of multiple target compounds in biological samples. (2016) (3)
- Crystal and molecular structure of 2:1 complex of 1,3-dimethyl violuric acid-mercury(II) (1990) (3)
- Clinical evaluation of a non-purified direct molecular assay for the detection of Clostridioides difficile toxin genes in stool specimens (2020) (3)
- Effects of Several Co-catalysis on Cyclic Polymerization of Acetylene under High Pressure (1958) (3)
- Natural flavour esters: production by Candida cylindracae lipase adsorbed to silica gel (1987) (3)
- Direct and Sensitized Valence Photoisomerization of a Substituted Norbornadiene. (1986) (3)
- In vitro inhibition and enhancement of liver microsomal S-777469 metabolism by long-chain fatty acids and serum albumin: insight into in vitro and in vivo discrepancy of metabolite formation in humans (2016) (3)
- Liquid chromatography-tandem mass spectrometry analysis of oxidation of 2′-, 3′-, 4′- and 6-hydroxyflavanones by human cytochrome P450 enzymes (2020) (3)
- Genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects identified by phenotyping for trimethylaminuria and found in a database of genome resources. (2021) (3)
- Interleukin-1β and tumor necrosis factor-α affect cytochrome P450 expression in cynomolgus macaque hepatocytes. (2020) (3)
- Rapid enzyme immunoassay of chicken egg yolk IgG. (1991) (3)
- Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital (2021) (3)
- The Long-range 1H-14N Spin Coupling in Transition Metal Complexes of Alkyl Isocyanides (1977) (3)
- Expression of cytochrome P450 regulators in cynomolgus macaque (2018) (3)
- Cytochrome P450 2J Genes Are Expressed in Dogs, Cats, and Pigs, and Encode Functional Drug-Metabolizing Enzymes (2022) (3)
- Differences in pharmacokinetics and haematotoxicities of aniline and its dimethyl derivatives orally administered in rats. (2021) (3)
- Developmental variations in metabolic capacity of (2010) (3)
- Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data. (2020) (3)
- Synthesis of μ-Oxo Complexes of Group 4 Bridged-Metallocenes: A Convenient Separation of meso and racemo Isomers (1998) (3)
- Thermally-induced production of hydrogen by dinuclear rhodium(I) complexes [1] (1981) (3)
- Synthesis and characterization of planar-chiral cyclopentadienylruthenium–vinylidene complexes (2001) (3)
- Pharmacokinetics of primary oxidative metabolites of thalidomide in rats and in chimeric mice humanized with different human hepatocytes. (2021) (3)
- A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine (2022) (3)
- Molecular characterization of UDP-glucuronosyltransferases 3A and 8A in cynomolgus macaques. (2020) (2)
- Evaluation of cytotoxic potential of cored soft contact lenses with adsorbed active ingredients from over-the-counter eye drops. (2012) (2)
- O I.4 Roles of human cytochrome P450s 1A1, 1A2, 1B1, 2E1, and 3A4/5/7 in the activation of environmental procarcinogens and promutagens (1997) (2)
- Treatment of endocrine disruptors in wastewater by using a white-rot fungal laccase immobilized into dialysis tubing. (2003) (2)
- Determination of the total rates of synthesis and degradation of RNA in a bacterial culture. (1981) (2)
- Effects of cholate and selenite on polymyxin-cloth enzyme immunoassay of Salmonella statically cultured in the presence of microflora from chicken faeces (1995) (2)
- Repeated batch antibiotic fermentation by streptomycetes immobilized on cotton cloth (1987) (2)
- Development of a genotyping tool for a functionally relevant CYP 2 C 19 allele ( Phe 100 Asn , Ala 103 Val and Ile 112 Leu ) in cynomolgus macaques (2015) (2)
- Long-term preservation of antibody activity and binding to polyester cloth by dessication (1996) (2)
- Human plasma concentration-time profiles of troglitazone and troglitazone sulfate simulated by in vivo experiments with chimeric mice with humanized livers and semi-physiological pharmacokinetic modeling. (2020) (2)
- A polymyxin-cloth enzyme immunoassay system for detection ofEscherichia coliO157 in ground beef (1996) (2)
- Synthesis of pppGpp by ribosomes from an Escherichia coli spoT mutant and the metabolic relationship between pppGpp and ppGpp. (1977) (2)
- Effect of genetic variants of the human flavin-containing monooxygenase 3 ( FMO 3 ) on Nand S-oxygenation activities 1 (2006) (2)
- An Environmentally Friendly , Highly Efficient , Lightweight Scroll Compressor ( QS 90 ) for Car Air Conditioners (2008) (2)
- Dimerization of Ethynylcyclopentadienylmetal Complexes (1999) (2)
- Newly identified tree shrew cytochrome P450 2B6 (CYP2B6) and pig CYP2B6b are functional drug-metabolising enzymes (2022) (2)
- Preparation and reactions of bis(isocyanide)(η5-indenyl)rhodium(I) complexes (1987) (2)
- Enzymic preparation of adenosine 5'-[beta-2P]triphosphate. (1977) (2)
- Molecular cloning, sequence analysis, and tissue distribution of marmoset monoamine oxidases A and B. (2020) (2)
- Molecular Cloning, Functional Expression, and Characterization of Isolectin Genes of Hemolytic Lectin CEL-III from the Marine Invertebrate Cucumaria echinata (2012) (2)
- A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs (2022) (2)
- Estimation of the real temperature of samples in IR cell using OH frequency of silica (2015) (2)
- Cloning and tissue expression of cytochrome P450 2S1, 4V2, 7A1, 7B1, 8B1, 24A1, 26A1, 26C1, 27A1, 39A1, and 51A1 in marmosets. (2019) (2)
- Cytochrome P450 2A6 phenotyping based on dietary caffeine intake in a Japanese population of non-smokers. (2012) (2)
- Activation of polyester cloth for the immobilization of a polysaccharide antigen (1990) (2)
- In vivo Analysis of the Anti-atrial Fibrillatory, Proarrhythmic and Cardiodepressive Profiles of Dronedarone as a Guide for Safety Pharmacological Evaluation of Antiarrhythmic Drugs (2017) (2)
- Obfuscating transparency? (2018) (2)
- Title Comprehensive evaluation for substrate selectivity of cynomolgus monkey cytochrome P 450 2 C 9 , a new efavirenz oxidase (2015) (2)
- Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance. (2021) (2)
- Use of bacterial films as resident inocula for repeated batch fermentation (1985) (2)
- Immunological detection of lipopolysaccharide antigens of thermophilic campylobacters captured on polymyxin-coated polyester cloth. (1996) (2)
- Formation of dicyanocobaltacyclopentanes from a cobalt(acrylonitrile) complex and isomerization of the cis-isomers via a polytopal rearrangement (1980) (2)
- Synthesis and structural characterization of the hydrido carbido ruthenium cluster [PPh4][Ru6C(CO)16H] (1992) (2)
- Corrigendum to "Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9" [Drug Metab Pharmacokinet 30 (2015) 130-132]. (2017) (2)
- Stereospecific interactions between tetrakis(.mu.-carboxylato)dirhodium antitumor agents and nucleic acid bases. Crystal structure of the rhodium complex [Rh2(acetato)4(AAMP).3.5H2O] (AAMP = 4-amino-5-(aminomethyl)-2-methylpyrimidine) (1984) (2)
- Novel variants in outer protein surface of flavin-containing monooxygenase 3 found in an Argentinian case with impaired capacity for trimethylamine N-oxygenation. (2020) (2)
- Synthesis of B-Organofunctional Borazine Derivatives: A Review of Recent Work at the Massachusetts Institute of Technology (1964) (2)
- Evidence for a third system for glucose uptake in Escherichia coli (1983) (2)
- Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes (2022) (2)
- Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments (2021) (2)
- Probe drug T-1032 N-oxygenation mediated by cytochrome P450 3A5 in human hepatocytes in vitro and in humanized-liver mice in vivo. (2022) (2)
- Combined Risk Assessment of Food-derived Coumarin with in Silico Approaches (2022) (2)
- Preparation of Alkyl-rhodium Complexes (1968) (2)
- Efficient and gentle elution of antibodies from an immobilized polypeptide antigen BT saturated magnesium chloride (1993) (2)
- Different substrate elimination rates of model drugs pH-dependently mediated by flavin-containing monooxygenases and cytochromes P450 in human liver microsomes. (2021) (2)
- Cellulose acetate entrapment of Escherichia coli on cotton cloth for aspartate production (1986) (2)
- Gas Phase Photocatalytic Degradation of Tetrachloroethylene in Water. (1998) (2)
- Genotoxicity of carcinogenic N-nitrosopropylamine derivatives in the hepatocyte primary culture/DNA-repair test. (1985) (2)
- Detection of dilute antigen in large sample volumes using antibody-coated polyester cloth (1995) (2)
- Species, Ethnic, and Individual Differences in Human Drug-Metabolizing Cytochrome P450 Enzymes (2014) (2)
- Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19 (2021) (2)
- Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5'-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species. (2021) (2)
- Drug-induced liver toxicity studies: research into human metabolites clarifies their role in drug development. (2014) (2)
- Adsorption of aspartase onto hydrophobic cloth for conversion of ammonium fumarate (1986) (2)
- Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney (2018) (2)
- Molecular cloning and tissue distribution of a novel marmoset ABC transporter (2018) (2)
- Enrichment of injuredSalmonellain poultry products for detection by polymyxin–cloth enzyme immunoassay (1998) (2)
- 3A-02 Effects of co-administration of food antioxidants and naturally occurring components, flavonoids on the activation of mutagens (1997) (2)
- Structures of tetrakis(μ-acetato)bis(2-amino-4,6-dimethylpyrimidine)dirhodium(II) and its monohydrate (1989) (2)
- Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3). (2020) (2)
- EFFECT OF SEGREGATION ON DYNAMIC RESPONSE OF A CONTINUOUS FLOW CHEMICAL REACTOR (1969) (2)
- Plasma, liver, and kidney exposures in rats after oral doses of industrial chemicals predicted using physiologically based pharmacokinetic models: A case study of perfluorooctane sulfonic acid. (2020) (2)
- Two types of inhibitory reflexes of the jaw-closing muscle elicited from the palate shelf in the frog (1984) (2)
- Expression levels of microRNAs that are potential cytochrome P450 regulators in cynomolgus macaques (2020) (2)
- Hepatotoxicological potential of P-toluic acid in humanised-liver mice investigated using simplified physiologically based pharmacokinetic models (2021) (2)
- Influence of BOD Adjuster on Domestic Wastewater Treatment and Microbial Community (2005) (1)
- Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes. (2023) (1)
- Polymerization of Ethylene with bis-Benzenechromium and Oxygen (1962) (1)
- Hepatic expression of cytochrome P450 enzymes in non‐human primate species (2017) (1)
- Structure of thiamine picrate (1988) (1)
- Crystal structure of (3,4-diphenyl-1-thiolene-2-one-5-thione)-bis(triphenylphosphine)palladium. (1989) (1)
- Individual differences in toxicological response caused by a diversity of chemicals: observations in Japan. (2008) (1)
- Different Effects of Polymorphic Flavin-containing Monooxygenase 3 and Cytochrome P450 2A6 Activities on an Index of Arteriosclerosis as a Lifestyle-related Disease in a General Population in Japan. (2020) (1)
- Comparison of catalytic and inhibitory properties in human drug-metabolizing cytochrome P450 3A4 and 3A5 for various compounds including endogenous steroid hormones and azole antifungals by molecular docking simulation (2017) (1)
- Evaluation of Greenhouse Gas Emissions from a Continuous Activated Sludge Process under Power Saving Conditions (2014) (1)
- Cytochrome P450s in chimeric mice with humanized liver. (2022) (1)
- Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans (2021) (1)
- Genetic variants of UDP-glucuronosyltransferases 1A1, 1A6, and 1A9 in cynomolgus and rhesus macaques (2020) (1)
- Effect of mixing on esterification of cepharosporic acid in a solid-liquid system (1989) (1)
- Affinity purification and biotinylation of antibodies on antigen-coated polyester cloth (1990) (1)
- mRNA levels of drug-metabolizing enzymes in 11 brain regions of cynomolgus macaques. (2019) (1)
- Advanced Mitigative Strategies of EU-ABWR Based on the Fukushima Accident (2012) (1)
- High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database. (2022) (1)
- Effects of Meat Intake Frequency and Polymorphic Cytochrome P450 2A6 Activity on Individual Colorectal Tumour Risk in a Japanese Cohort (2017) (1)
- Preparation of high surface area ZrO2 and ZrO2-Y2O3 from the alkoxide (1994) (1)
- Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia. (2013) (1)
- Genetic variants of aldehyde oxidase (AOX) 1 in cynomolgus and rhesus macaques (2021) (1)
- Comparison of mouse and human cytochrome P450 mediated-drug metabolising activities in hepatic and extrahepatic microsomes (2022) (1)
- Instantaneous cloth-based enzyme immunoassay for the semi-quantitative visual determination of antibodies. (1997) (1)
- Roles of cytochrome P450 2A6 in the oxidation of flavone, 4′-hydroxyflavone, and 4′-, 3′-, and 2′-methoxyflavones by human liver microsomes (2021) (1)
- Resistance of bacterial film to contamination during use as inoculum in repeated batch fermentation (2005) (1)
- Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors. (2016) (1)
- Roles of Human CYP 2 A 6 and Monkey CYP 2 A 24 and 2 A 26 Cytochrome P 450 Enzymes in the Oxidation of 2 , 5 , 2 ́ , 5 ́Tetrachlorobiphenyl ́Tetrachlorobiphenyl ́Tetrachlorobiphenyl (2016) (1)
- Development of High-efficiency Scroll Compressor for Automotive Air Conditioners (2017) (1)
- UDP-glucuronosyltransferase 1A4-mediated N2-glucuronidation is the major metabolic pathway of lamotrigine in chimeric NOG-TKm30 mice with humanised-livers (2021) (1)
- Extrapolation of Hepatic Concentrations of Industrial Chemicals Using Pharmacokinetic Models to Predict Hepatotoxicity (2019) (1)
- Plasma concentration profiles for hepatotoxic pyrrolizidine alkaloid senkirkine in humans extrapolated from rat data sets using a simplified physiologically based pharmacokinetic model. (2021) (1)
- Drug-Metabolizing Enzyme Systems I (2017) (1)
- Application of vibration milling for advanced wastewater treatment and excess sludge reduction. (2011) (1)
- Effects of Installation of Water-saving Devices on the Performance of Johkasou (2016) (1)
- Process Development of a Novel Non-xanthine Adenosine A1 Receptor Antagonist. (2000) (1)
- Greenhouse Gases Control and Water Purification Performance in a Johkasou System under Energy Saving Operation (2015) (1)
- Regulatory relationship between PTSM and PTSG in Escherichia coli (1983) (1)
- NEUTRAL AND CATIONIC RHODIUM COMPLEXES OF 2,6-DISUBSTITUTED PHENYL ISOCYANIDES. CRYSTAL STRUCTURE ANALYSIS OF CHLOROTRIS(2,4,6-TRI-TERT-BUTYLPHENY ISOCYANIDE)RHODIUM(I) AND ESTIMATION OF BULKINESS IN THE ISOCYANID SUBSTITUENT (1979) (1)
- Detection of human blood by cloth-based enzyme immunoassay of immunoglobulin G (1995) (1)
- Effects of Power Saving on Treatment Water Quality and Biota Characteristics in an Activated Sludge Process of SewageTreatment (2011) (1)
- Activation of Rayon/Polyester Cloth for Protein Immobilization (1997) (1)
- Isolation and characterization of catabolite repression-resistant mutants of Escherichia coli. (1977) (1)
- INACTIVATION EFFECT OF UV-LED ON INDICATOR BACTERIA IN JOHKASOU EFFLUENT WATER (2020) (1)
- Unusual reductive behaviour of a trans-NiI2(RNC)2 complex at mercury and platinum electrodes (1991) (1)
- Disparity in Holo/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes (2007) (1)
- Thiamine‐Metal Ion and Thiamine‐Anion Interactions. Crystal Structure of Cu(thiamine)Br2. (1989) (1)
- Comparison of reconstitution conditions for recombinant human P450 2C9 with systems containing P450S 1A1, 1A2, 2D6, 2E1, and 3A4. Effects of P450-P450 and P450-b(5) interactions (1997) (1)
- Predictability of human pharmacokinetics of diisononyl phthalate (DINP) using chimeric mice with humanized liver (2019) (1)
- [Message from the President of the Japanese Society for the Study of Xenobiotics]. (2019) (1)
- A Survey of Adverse Effects and Risk Factors for Topical Dermatological Application of Diclofenac (2014) (1)
- Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes. (2022) (1)
- Novel Cytochrome P450 2C94 Functionally Metabolizes Diclofenac and Omeprazole in Dogs (2023) (1)
- Simple transductional method for constructing adenylyl cyclase deletion strains of Escherichia coli K-12 (1983) (1)
- Recent Developments in Transition Metal-Catalyzed Polymerization I. Polymerization of Propylene by Silylene- and Germylene-Bridged Group 4 Metallocenes. (2002) (1)
- Combustion Mechanism of Rich-Lean Flame Burner Controlled Boundary Zone (2007) (1)
- Study of Intramolecular Sensitization and Other Excited-State Pathways in Orthometallated Azobenzene Complexes of Palladium(II). (1986) (1)
- Excitatory and inhibitory reflexes of the jaw-closing muscle elicited from the palate marginal region in the frog (1983) (1)
- Newly Identified Tree Shrew Cytochrome P450 2A13 is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to Dog Cytochrome P450 2A13 and Pig Cytochrome P450 2A19 (2023) (1)
- Updated in Silico Prediction Methods for Fractions Absorbed and Key Input Parameters of 355 Disparate Chemicals for Physiologically Based Pharmacokinetic Models for Time-Dependent Plasma Concentrations after Virtual Oral Doses in Humans. (2022) (1)
- Further survey of genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found in an updated database of genome resources and identified by phenotyping for trimethylaminuria. (2022) (1)
- Rapid detection of dilute lipopolysaccharide antigens in large volumes using polymyxin-coated polyester cloth (1997) (1)
- Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations (2020) (1)
- [P450 and carcinogenesis]. (2002) (1)
- Fabrication and Properties of (1-x)BiScO3-xPbTiO3 Thin Films Through Metal-Organic Compounds (2004) (0)
- COBALT METALLOCYCLES. IV. RING OPENING OF COBALTACYCLOPENTADIENES BY ADDITION N OF SILICON-HYDROGEN, SULFUR-HYDROGEN, NITROGEN-HYDROGEN AND CARBON-HYDROGEN TO THE DIENE MOIETY (1978) (0)
- Human plasma concentration-time profiles of troglitazone and troglitazone sulfate estimated by in vivo experiments with chimeric mice wth humanized livers (2017) (0)
- 活性汚泥法[に]おける処理水質および生物特性に及ぼす省電力化の影響解析 (2011) (0)
- Rhodium Carbonyl-Catalyzed Carbonylation of Unsaturated Compounds. Part 3. Synthesis of α,β-Unsaturated Ethyl Ketones by Cross-Hydrocarbonylation of Acetylenes and Ethylene with Carbon Monoxide and Hydrogen. (1988) (0)
- Four Carbon Component Coupling Reaction Based on Free-Radical Carbonylation: An Easy Access to β-Functionalized δ,. epsilon.-Unsaturated Ketones. (2010) (0)
- Syntheses and Structures of Methyl-, Acetyl- and Allyl-Ruthenium Carbidocarbonyl Clusters. (1990) (0)
- Chronic atrioventricular block model of micro-mini pigs: A new proarrhythmia model for drug-induced torsades de pointes (2010) (0)
- SOME REACTIONS OF PI-CYCLOPENTADIENYL-BIS(TRIPHENYLPHOSPHINE)RHODIUM(I) (1974) (0)
- Application of antibody adsorbed polyester cloth for the rapid screening of elution conditions for antigen immunopurification. (1996) (0)
- Examination of the Design Method and the Treatment Performance concerning the Localization of Japanese Johkasou for Foreign Regions (2018) (0)
- Synthesis of Optically Active N-(1-Ethyl-3-methylhexahydro-1,3-diazin-5-yl)- and N-(1-Ethyl-5-methyloctahydro-1,5-diazocin-3-yl)pyridine-3-carboxamides. (2002) (0)
- Validation of a Serum S-100B ELISA for Measuring S-100B in Cerebrospinal Fluid (2016) (0)
- P119 - Drug-metabolizing activity and cytochromes P450 induction in human hepatocytes from TK-NOG chimeric mice with humanized livers (2020) (0)
- Behavior Analysis of Sanitary Indicator Bacteria in Treatment Process of Johkasou (2018) (0)
- Infrared study on mechanisms of C-C bond formation during methanol-to-hydrocarbons reaction over ZSM-5 zeolite (2014) (0)
- EMISSION CHARACTERISTICS OF GREENHOUSE GASES (CH 4 ·N 2 O) CONSIDERING SEASONAL FLUCTUATIONS FROM JOHKASOU (2018) (0)
- Cytogenetic Studies on the Artificial Polyploids in the Genus Oryza. : VII. Auto-triploid and -tetraploid plants of O. australiensis Domin. (1973) (0)
- REACTION OF A DIPHENYLACETYLENE-COBALT COMPLEX WITH ALKYL DIAZOACETATES (1978) (0)
- Organic Synthesis by Low-Valent Isocyanide Complexes. Part 5. Formation of Indolenine Derivatives from Dicobalt Octaisocyanide and Carbon Polyhalide. (1989) (0)
- Chronic atrioventricular block model of microminipig: New in vivo model for drug-induced lethal arrhythmias (2011) (0)
- ADME of Anticancer Drugs (2012) (0)
- Identification and characterization of cytochrome P450 4F enzymes in marmosets (2017) (0)
- Polymerizations of unsaturated compounds by bis-benzenechromium,4. (1963) (0)
- Suppression of N 2 O Greenhouse Gas Emission Volume using the Flow Equalization Function in Johkasou (2018) (0)
- REACTION OF A DIPHENYLACETYLENE COMPLEX OF COBALT WITH ISOCYANIDE, A NOVEL METALLORING FORMATION (1975) (0)
- NOVEL CATALYTIC DIMERIZATION OF TERT-BUTYLACETYLENE TO TRANS-1,4-DI-TERT-BUTYLBUTATRIENE (1977) (0)
- Crystal Structure of Bis(triphenylphosphine)dithiocarbamatorhodium Bis(maleate) (1990) (0)
- G0601-2-5 Thermal regeneration Characteristic of Regenerator in Stirling Engine (2009) (0)
- Human and monkey P450 metabolism for human-specific metabolite formation (2017) (0)
- STUDIES ON INTERACTIONS OF ISOCYANIDES WITH TRANSITION METAL COMPLEXES PART 9, SINGLE AND MULTIPLE INSERTION OF ISOCYANIDE INTO PALLADIUM-TO-CARBON SIGMA BONDS (1974) (0)
- 1931 Combustion Mechanism of Rich-Lean Flame Burner controlled Secondary Airflow (2007) (0)
- STUDIES ON INTERACTIONS OF ISOCYANIDES WITH TRANSITION METAL COMPLEXES PART 10, PREPARATION AND REACTIONS OF ALKYLIRON COMPLEXES CONTAINING ISOCYANIDE (1974) (0)
- OMEPRAZOLE HYDROXYLATION BY CYP2C19 AND CYP3A4: PREDICTION TOWARDS HUMAN LIVER ACTIVITIES USING THE DATA OF RECOMBINANT P450 ENZYMES (1997) (0)
- Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital (2021) (0)
- Systematic identification and characterization of cynomolgus macaque solute carrier transporters. (2021) (0)
- Cardiohemodynamic and Electrophysiological Effects of Anti-influenza Drug Oseltamivir In Vivo and In Vitro (2013) (0)
- CYP2D44 polymorphisms in cynomolgus and rhesus macaques (2015) (0)
- Roles of human cytochrome P450 3A4/5 in dexamethasone 6β-hydroxylation mediated by liver microsomes and humanized liver in chimeric mice metabolically suppressed with azamulin. (2023) (0)
- Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital (2021) (0)
- Correction to "An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Concentrations after Oral Doses in Rats". (2022) (0)
- Plasma and synovial fluid concentrations of linezolid in patients with knee osteoarthritis infected with Staphylococcus aureus (2022) (0)
- US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations. (2023) (0)
- Bis(9‐triptycyl)amines, a Missing Link between the Corresponding Methanes and Ethers. (1986) (0)
- Trivariate Linear Regression and Machine Learning Prediction of Possible Roles of Efflux Transporters in Estimated Intestinal Permeability Values of 301 Disparate Chemicals. (2022) (0)
- RHODIUM CARBONYL CLUSTER CATALYZED ADDITION OF ARENES TO DIPHENYLKETENE AND ARYL ISOCYANATES (1978) (0)
- True induction of the phosphoenolpyruvate‐glucose phosphotransferase system in Escherichia coli (1983) (0)
- Influence of Polyferric Sulfate Coagulant on the amoA mRNA Expression of Ammonia Oxidizer in Activated Sludge (2010) (0)
- vivo Probe for Studying Induction of CYP 3 A in Cynomolgus Monkeys (2010) (0)
- Editorial. (2019) (0)
- Oxidation of 3’-methoxyflavone, 4’-methoxyflavone, and 3’,4’-dimethoxyflavone and their derivatives having 5,7-dihydroxyl moieties by human cytochromes P450 1B1 and 2A13 (2022) (0)
- Low cerebrospinal fluid-to-plasma ratios of orally administered lenalidomide mediated by its low cell membrane permeability in patients with hematologic malignancies (2022) (0)
- The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers (2023) (0)
- Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital (2020) (0)
- Cloning and tissue expression of ATP-binding cassette transporters in cynomolgus macaques. (2021) (0)
- Polymorphic cytochromes P450 in non-human primates. (2022) (0)
- Variants of Flavin-containing Monooxygenase 3 (FMO3) Found in Subjects in an Updated Database of Genome Resources. (2023) (0)
- Cobalt Metallacycles. Part 16. X-Ray Structures of 4-Iminocobaltacyclobutene Complexes. (1986) (0)
- SYNTHESIS AND SOME REACTIONS OF η5-PENTAMETHYLCYCLOPENTADIENYLNICKEL COMPLEXES (1979) (0)
- A MODEL FOR COENZYME-METAL ION-APOENZYME INTERACTIONS: CRYSTAL STRUCTURE OF THE TERNARY COMPLEX ((THIAMINE PYROPHOSPHATE)(1,10-PHENANTHROLINE)AQUACOPPER)-DINITRATE-WATER (1981) (0)
- The characteristic of human CYP3A4 catalytic activity. (1998) (0)
- Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes (2014) (0)
- Studies in Organotransition Metal Complexes (1987) (0)
- Genetic variants of CYP 3 A 4 and CYP 3 A 5 in cynomolgus and rhesus macaques (2009) (0)
- Induction of human cytochrome P450 3A enzymes in hepatic and placental cells by thalidomide and relevance to bioactivation (2018) (0)
- Selective Synthesis of Oxygenates in the CO‐H2 Reaction on Supported Ruthenium Carbido‐Cluster Catalysts. (1993) (0)
- HepaSH cells: Experimental human hepatocytes with lesser inter-individual variation and more sustainable availability than primary human hepatocytes. (2023) (0)
- A process for the preparation of substituted olefins (1980) (0)
- Drug Interactions Mediated by Drug-Metabolizing Enzymes (2013) (0)
- Molecular and Functional Characterization of N-Acetyltransferases in Common Marmosets and Pigs (2022) (0)
- ORGANIC SYNTHESIS BY LOW-VALENCE ISOCYANIDE COMPLEXES. IV. THE OLIGOMERIZATION AND CO-OLIGOMERIZATION OF ACTIVE METHYLENE COMPOUNDS AND ISOCYANIDES CATALYZED BY OCTAISOCYANIDEDICOBALT (1981) (0)
- η5-METHOXYCARBONYLCYCLOPENTADIENYL-η4-1,5-CYCLOOCTADIENECOBALT (1988) (0)
- Advanced Ammonia Oxidation by Adding Metabolic Mediator (2005) (0)
- TROGILTAZONE METABOLISM AND CYTOTOXIC EFFETS (2000) (0)
- A family study of compound variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found by urinary phenotyping for trimethylaminuria. (2023) (0)
- THERMALLY-INDUCED PRODUCTION OF HYDROGEN BY DINUCLEAR RHODIUM(I) COMPLEXES (1981) (0)
- Heterogeneous Cobalt Catalysts for the Acceptorless Dehydrogenation of Alcohols. (2013) (0)
- Analysis of Relationship among the Influent load, Micro biota and Purification Function in the Wastewater Treatment System Coupled with Disposer (2006) (0)
- Roles of rat and human epoxide hydrolase inhydrolysis of aflatoxin B_1 8, 9-epoxide (1998) (0)
- The Binuclear Iridium(II) Hydride Complex [(C5Me5)Ir(μ-H)]2: A Novel Base for Reversible Deprotonation of Acidic Organic Compounds and a Unique Catalyst for C—C Bond Cleavage of Aromatic 1,2-Diols and Michael Additions. (2001) (0)
- Metabolic profiles of benzydamine in humanized-liver mice (2018) (0)
- Polymorphisms of cytochrome P450 2B6 (CYP2B6) in cynomolgus and rhesus macaques (2018) (0)
- Interaction of Isocyanide with Transition-Metal Complexes. Part 33. Low-Valent Isocyanide Complexes and Clusters of Palladium and Platinum. Crystal Structure of Cyclic (Pt(C(=NR)N(R)C(=NR))(RNC)2) (R: 2,6-Me2C6H3). (1990) (0)
- Establishment of in silico systems to predict the effects of genetic polymorphism on the enzymatic activity of cytochrome P450 (2006) (0)
- ANALYSIS OF GREENHOUSE GAS EMISSIONS MITIGATION IN THE JOHKASOU SECTOR AND CONSIDERASTION OF MITIGATION POLICY (2018) (0)
- Ruthenium‐Catalyzed Disproportionation Between Vinylsilanes and Mono‐ Substituted Alkenes via Silyl Group Transfer. (1991) (0)
- RHODIUM-CATALYZED CARBONYLATION OF UNSATURATED COMPOUNDS. 1. RHODIUM CARBONYL-CATALYZED CARBONYLATION OF ACETYLENES IN THE PRESENCE OF ETHYLENE. SYNTHESIS OF 5-ETHYL-2(5 H)-FURANONES (1982) (0)
- Liver microsomal cytochrome P450 3A-dependent drug oxidation activities in individual dogs. (2023) (0)
- DI-μ-CARBONYL-BIS(η5-PENTAMETHYLCYCLOPENTADIENYL)-DINICKEL(I) (1986) (0)
- Estimation of Internal Radiation Dose in Human Based on Animal Data―Application of Methodology in Drug Metabolism and Pharmacokinetics― (2015) (0)
- In vivo preparation of [32P]cAMP and thin-layer chromatography of cAMP-related compounds. (1979) (0)
- Steric Effects of Ligands in Silver(I) Isocyanide Complexes. Structure of Ag(2,4,6- t-Bu3C6H2NC),(PF6) Containing a Bidentate PF6Ligand. (1983) (0)
- The Reaction Mechanism of Ruthenium-Catalyzed Dimerization of tert-Butylacetylene to cis-1,4-Di-tert-butylbutatriene. Involvement of a Ruthenium Diacetylide Intermediate. (1990) (0)
- Preparation, Properties, and Some Reactions of Novel Ruthenium Thiolate Complexes. (1989) (0)
- P39 - Metabolism of desloratadine in TK-NOG chimeric mice with humanized livers (2020) (0)
- Preparation of Chiral Tricarbonyl Arene Thiol Chromium and Its Application to Asymmetric Ring Opening of meso-Epoxides. (1998) (0)
- Meet the Editorial Board Member (2021) (0)
- CRYSTAL AND MOLECULAR STRUCTURE OF 1,1′-(TETRAPHENYL-O-PHENYLENE)FERROCENE (1977) (0)
- X-Ray Studies on Metal Ion Interactions with Vitamins. Part 1. (1986) (0)
- On Fixation of Spores of the Laver, Parphyra tenera, in the Hiroshima Bay-II (1953) (0)
- Analysis of Microbial Solubilization and Decomposition of Disposer Wastewater. (2008) (0)
- BIDENTATE ISOCYANIDES. I. SYNTHESIS OF DIISOCYANOCYCLOHEXANES AND SOME OF THEIR COMPLEXES (1981) (0)
- Pain modulation by noradrenaline in the spinal dorsal horn (1989) (0)
- Effects of multi-kinase inhibitors on the activity of cytochrome P450 2J2 (2022) (0)
- Crystal and molecular structure of 2∶1 complex of 1,3-dimethyl violuric acid-mercury (II) (1990) (0)
- Metabolic Activation of Procarcinogens by Human Cytochrome P450 Enzymes in Microsomes of Adult and Fetal Livers and of Adult Lungs (1995) (0)
- Comparison Study on Sludge Storage Capacity between Japanese Model and the EU Model of Small-Scale Wastewater Treatment System (Johkasou) (2017) (0)
- 1842 On the Effective Utilization of Regenerator Space in Stirling Engine (2007) (0)
- Evaluation of domain of unknown function 1220 (DUF1220) for detection of human genome by quantitative polymerase chain reaction: Potential use in assessing the biodistribution of transplanted therapeutic human cells. (2020) (0)
- RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES (2000) (0)
- METABOLIC ACTIVATION OF N-NITROSOBIS (2-HYDROXYPROPYL) AMINE BY RATS (1986) (0)
- COBALT METALLOCYCLES. PART 9. SOME REACTIONS OF COBALTAINDENE, COBALTAFLUORENE, COBALTAXANTHENE, AND COBALTACYCLOPENTANE COMPLEXES (1980) (0)
- Effects of High Circulation Ratio on Biological Nitrogen Removal in Anaerobic-aerobic Wastewater Treatment System (2006) (0)
- A comparative study of the mutagenic activation of carcinogenic N-nitrosopropylamines by various animal species and man. (1987) (0)
- Variations in contents of liver microsomal cytochrome P450 isofoms and activities of drug oxidations in humans (1999) (0)
- METABOLIC ACTIVATION OF 3-METHOXY-4-AMINOAZOBENZENE BY LIVER MICROSOMES : CONTRIBUTION OF DIFFERENT FORMS OF RAT AND HUMAN CYTOCHROME P-450 ENZYMES IN THE REACTION (1991) (0)
- High-purity titanium complex and its production (1992) (0)
- The Crystal Structure and Electronic Properties of the Bis(1,3-dimethyl-5-diazophenyl-6-amino uracilato) Copper(II) Complex, Dimethyl Sulfoxide Solvate - A New Pseudotetrahedral CuN4 Complex. (1990) (0)
- Life Cycle CO 2 Evaluation for Household Johkasou System with Garbage Disposer (2008) (0)
- Plasma and hepatic exposures of celecoxib and diclofenac prescribed alone in patients with cytochrome P450 2C9*3 modeled after virtual oral administrations and likely associated with adverse drug events reported in a Japanese database. (2023) (0)
- 6-methoxy-1H-benzotriazole-5-carboxamide derivatives, process for their preparation and pharmaceutical compositions containing them (1997) (0)
- Polymers with high acid values, their use and processes for their preparation (1996) (0)
- The change of the catalase activity in laver by waste (1959) (0)
- Forward and reverse dosimetry for aniline and 2,6-dimethylaniline in humans extrapolated from humanized-liver mouse data using simplified physiologically based pharmacokinetic models. (2022) (0)
- [Pharmacogenomic data for personalized medicines]. (2005) (0)
- [PHARMACOLOGY OF SUBSTANCES OF THE NUCLEIC ACID SERIES]. (1963) (0)
- Cobalt Metallacycles. Part 15. Regioselective Formation and Rearrangement of 4-Iminocobaltacyclobutene Complexes. (1986) (0)
- Preparation of 2-pyridone compound (1979) (0)
- Effects of Water-saving Devices on Greenhouse gases emission from Johkasou. (2017) (0)
- MACHINE HYDRAULIQUE À SPIRALE (2008) (0)
- Thermolysis of acetylenecobalt complexes: A novel route to biscarbyne complexes, (.MU.3.ETA.1-CR1)(.MU.3.ETA.1-CR2)[(.ETA.5-C5H5)Co]3. (1979) (0)
- COBALT METALLOCYCLES. I. ONE-STEP AND STEPWISE SYNTHESIS OF COBALTACYCLOPENTADIENE COMPLEXES FROM ACETYLENES (1978) (0)
- Free‐Radical Carbonylation. Conversion of Aromatic Halides to Aldehydes. (1992) (0)
- Solid Concentration Profiles in a Stirred Tank (1983) (0)
- Effect of solubilization of stored sludge on treatment performance in Johkasou (2020) (0)
- Cloning, sequence analysis, and tissue expression of marmoset paraoxonase 1. (2021) (0)
- STUDIES ON INTERACTIONS OF ISOCYANIDE WITH TRANSITION METAL COMPLEXES. 25. STRUCTURE OF TETRAKIS(2,6-XYLYL ISOCYANIDE)RHODIUM(I) 7,7,8,8-TETRACYANO-P-QUINODIMETHANE, (RH(2,6-ME2C6H3NC)4)+(TCNQ.CNTDOT.-) (1984) (0)
- Rhodium Carbonyl‐Catalyzed Carbonylation of Unsaturated Compounds. Part 5. Cross‐Hydrocarbonylation of 1‐Alkyne and Ethylene by Rhodium Carbonyl Catalyst Modified with Phosphines. (1991) (0)
- Development of the advanced on-line BWR core monitoring system TiARA (1996) (0)
- Advanced Treatment and Life Cycle CO 2 Evaluation for Household Johkasou System with Garbage Disposer (2010) (0)
- Difference between glucose inhibition of glycerol and lactose utilization in Escherichia coli (1983) (0)
- Analysis of Relationship between Water Temperature History and Average BOD of the Treated Water in Johkasou (2013) (0)
- Axially Dissymmetric 2,2′‐Diisocyano‐1,1′‐binaphthyl and Its Platinum Complexes. (1986) (0)
- Genotoxicity of a Variety of Azobenzene and Aminoazobenzene Compounds in the Hepatocyte/DNA Repair Test and the SVÃ ̄//n0/ie//fl/MutagenicityTest (2006) (0)
- Double Alkylation of Carbon Monoxide via Free Radicals: Synthesis of Unsymmetrical Ketones. (1992) (0)
- EFFECTS OF HISTIDINE-TAG ON RECOMBINANT HUMAN P450 3A5 CATALYTIC ACTIVITY IN RECONSTITUTION SYSTEMS (2009) (0)
- [Serotype and susceptibilities to eight antibiotics of fifty strains of Pseudomonas aeruginosa isolated from clinical specimens and changes in susceptibilities of Pseudomonas aeruginosa to various antibiotics during a period between 1983 and 1986]. (1988) (0)
- Updated in silico prediction methods for fractions absorbed and absorption rate constants of 372 disparate chemicals for use in physiologically based pharmacokinetic models for estimating internal concentrations in rats. (2022) (0)
- Expression and induction ability of cytochrome P450 in human hepatocytes isolated from chimeric mice with humanized livers (2019) (0)
- ADDITION OF 5-MEMBERED AROMATIC HETEROCYCLIC COMPOUNDS TO ACETYLENES CATALYZED BY TETRARHODIUM DODECACARBONYL: SYNTHESES OF VINYL SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS (1980) (0)
- Running Title Page Running title : Cloning of marmoset AOX 1 cDNA (2017) (0)
- Study of Metabolism and Cytotoxicity of Troglitazone (2001) (0)
- Interactions of Isocyanides with Transition Metal Complexes. Part 29. Isocyanide Complexes with Pt2S and Pt2CS Cores. Crystal Structure of μ‐Sulphido‐bis[bis(2,4,6‐tri‐t‐butylphenyl isocyanide)platinum]. (1986) (0)
- COBALT METALOCYCLES. II. DIELS-ALDER TYPE REACTION OF COBALTACYCLOPENTADIENES S WITH OLEFINS (1978) (0)
- Long-Term Limitation Effects of Se(VI), Zn(II), and Ni(II) on Start-Up of the Anammox Process Using Gel Carrier (2022) (0)
- Apparatus for reducing the dissolved oxygen (1994) (0)
- Recommended strategies for investigating cytochrome P450 contributions on the candidate metabolism at drug discovery stage: Applications for the reaction phenotyping (2011) (0)
- CHEMISTRY OF MIXED TRANSITION-METAL COMPLEXES PART 6, CRYSTAL AND MOLECULAR STRUCTURE OF (PI-C5H5)FE3(CO)7C2C6H5 OBTAINED FROM (PI-C5H5)FE(CO)2 -C-CC6H5 WITH FE2(CO)9 (1975) (0)
- Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism (2022) (0)
- Interactions of Isocyanides with Transition Metal Complexes. Part 31. Preparation and Reactions of Bis(isocyanide)(η5-indenyl)rhodium(I) Complexes. (1987) (0)
- The Crystal and Molecular Structures of a Novel It-Allyl Palladium Complex, ltt-Allyl-la-iodo-bis(triphenylphosphine palladium) Benzene Solvate (1972) (0)
- Regional distributions of UDP-glucuronosyltransferase activities toward estradiol and serotonin in the liver and small intestine of cynomolgus macaques. (2020) (0)
- Correction to "Plasma and Hepatic Concentrations of Chemicals after Virtual Oral Administrations Extrapolated Using Rat Plasma Data and Simple Physiologically Based Pharmacokinetic Models". (2019) (0)
- G0600-4-1 Effect of flow pattern on heat exchange of regenerator for Stirling engine. (2010) (0)
- Synthesis of 2-Pyridones by the Co-Trimerization of Acetylenes and Isocyanates. (1976) (0)
- On Kuei-têng Tsung-mi (1967) (0)
- Syntheses of Organometallic n-Complexes. (1966) (0)
- 2-Oxidation, 3-methyl hydroxylation, and 6-hydroxylation of skatole, a contributor to the odour of boar-tainted pork meat, mediated by porcine liver microsomal cytochromes P450 1A2, 2A19, 2E1, and 3A22 (2023) (0)
- Distribution and metabolism of N-nitrosobis(2-hydroxypropyl)amine in rats. (1984) (0)
- Regio- and Stereocontrolled Dimerization of tert-Butylacetylene to (Z)- 1,4-Di-tert-butylbutatriene by Ruthenium Catalysis. Reaction Mechanism Involving Alkynyl-Vinylidene Coupling and Rearrangement of the Metal- Bound C4 Unit. (1992) (0)
- Toxicological roles of human and rodent CYP2As in the mutagenic activation of N-nitrosamines.(GENERAL SESSION BY ORAL PRESENTATION)(DRUG METABOLISM) (2002) (0)
- STUDIES ON THE INTERACTION OF ISOCYANIDE WITH TRANSITION-METAL COMPLEXES. 15. EW TYPE OF INSERTION REACTIONS OF ISOCYANIDE INTO ALKYLIRON COMPLEXES (1978) (0)
- Correlation of the Two Torsional Degrees of Freedom About the Bonds Connecting the Bridgehead Carbons to the Sulfur Atom in Bis(9-triptycyl) Sulfide. (1987) (0)
- Performance Improvement of R e f r i g e r a t i n g a n d A i r-conditioning Systems with 3 D Scroll Compressors 1 (2006) (0)
- X-Ray Structures and Far-IR and Raman Spectra of Tetrahedral Thiophenolato and Selenophenolato Complexes of Zinc(II) and Cadmium(II). (1988) (0)
- 6-methoxy-1H-benzotriazole-5-carboxamide derivatives, process for their preparation and medicines containing them (1995) (0)
- Ruthenium Catalyzed Dimerization of Trimethylsilylacetylene to 1,4‐Bis( trimethylsilyl)butatriene and Its Isomerization to (Z)‐1,4‐Bis( trimethylsilyl)‐1‐buten‐3‐yne. (1993) (0)
- AN ENZYMIC MECHANISM FOR MUTAGENIC ACTIVATION OF CARCINOGENIC AMINOAZO DYES (1985) (0)
- First Isolation of a Tris(ketyl) Metal Complex. (1996) (0)
- Conceptual Design of European Advanced Boiling Water Reactor (EU-ABWR) (2010) (0)
- A Convergent Enone Synthesis. Three-Component Coupling of Alkyl Iodides, Carbon Monoxide, and Allylstannanes by Free-Radical Carbonylation. (1992) (0)
- Elucidation of parmacokinetics of PF-04937319, a partial glucokinase activator, and its disproportionate n-demethylated metabolite in chimeric mice with humanized livers (2017) (0)
- Novel 2-pyridone compounds and their preparation (1976) (0)
- 21805 Evaluation of Regenerator Performance in Stirling Engine (2007) (0)
- Novel Regioselection in Insertion of a 1,4‐Disubstituted 1,3‐Enyne into Ruthenium‐Hydrogen Bonds. (1991) (0)
- CYP2C76 deficiency is embryonic lethal in cynomolgus macaques: The potential role of CYP2C76 in early embryogenesis. (2017) (0)
- Erratum (2002) (0)
- PREPARATION AND REACTIONS OF CHLOROTRIS(2,6-XYLYL ISOCYANIDE)RHODIUM (1978) (0)
- Cobalt Metallacycles. Part 14. Facile Transformation of η4-Diene Complexes to Metallacyclopentenes. (1986) (0)
- A Novel Series of N-(Hexahydro-1,4-diazepin-6-yl) and N-(Hexahydroazepin-3-yl)benzamides with High Affinity for 5-HT3 and Dopamine D2 Receptors. (1998) (0)
- Development of greenhouse gases emission factor from organic wastewater discharged into water environment (2020) (0)
- [In vitro combination effects of astromicin and beta-lactam antibiotics against CFS-sensitive and CFS-resistant Pseudomonas aeruginosa. In vitro synergistic activity]. (1988) (0)
- Preparation and Structural‐Bonding Characterization of a 50‐Electron Triangular Cobalt Cluster, (Co(C5H4CO2Me))3(S)(NtBu), with Triply Bridging Sulfido and Imido Ligands: Singlet‐Triplet Equilibrium in Solid and Solution States. (1988) (0)
- P205 - Determination of permeability across Caco-2 cell monolayer and development of predictable equations for oral absorbability of general chemical substances (2020) (0)
- Synthesis and X-Ray Structure Analysis of the Tetracapped Octahedral Ruthenium Carbido Cluster (N(PPh3)2)2(Ru10C(CO)24). (1989) (0)
- On the Effect of Thermo-Electrically Cooled Baffle in Oil Diffusion Pump System (1968) (0)
- SYNTHESES OF 1,3-DISUBSTITUTED 5-(METHOXYCARBONYLMETHYLENE)-HYDANTOINS BY COBALT-CATALYZED 1-2 CYCLOCOTRIMERIZATION OF METHYL PROPIOLATE WITH ISOCYANATES (1978) (0)
- Cobalt Metallocycles. Part 10. Preparation and X-Ray Structures of Two Isomeric Dicyanocobaltacyclopentanes. (1983) (0)
- Asymmetric Methoxyselenenylation of Alkenes with Chiral Ferrocenylselenium Reagents. (1998) (0)
- Rhodium Carbonyl Catalyzed Carbonylation of Unsaturated Compounds. Part 4. Carbonylation and Oligomerization of Diphenylacetylene Catalyzed by Co4(CO)12, Rh4(CO)12, and Ir4(CO)12 Under Pressure of Carbon Monoxide. (1990) (0)
- Cytochrome P450 3A enzyme-dependent thalidomide toxicity and inducibility in cultured human placental cells (2019) (0)
- A n + 1 Strategy for Macrocyclization Based on Free-Radical Carbonylation. (1994) (0)
- A sensitive umu test system for detecting genotoxicity of mutagenic dihaloalkanes using Salmonella typhimurium tester strain expressing rat glutathione S-transferase (1996) (0)
- CHEMISTRY OF MIXED TRANSITION-METAL COMPLEXES. VII. IRON- AND NICKEL-SUBSTITUTED CYCLOBUTADIENE COMPLEXES OF COBALT (1977) (0)
- Functional analysis in decentralized domestic wastewater treatment system "Johkasou" for prevention eutrophication (2007) (0)
- MIXED-METAL CLUSTERS OF ISOCYANIDE CONTAINING A MERCURY ATOM IN THE CENTER OF A TRIGONAL-PRISMATIC PLATINUM FRAMEWORK. HG(PT3(2,6-ME2C6H3NC)6)2 (1982) (0)
- Algae Growth Inhibition Test of the Treated Water from Single and Combined Treatment Septic Tank Using Whole Effluent Toxicity Method (2020) (0)
- The European Version of the Advanced Boiling Water Reactor - EU-ABWR (2014) (0)
- Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments (2021) (0)
- Synthesis of Macrocyclic Ketoesters by an n + 1 Strategy Based on Free-Radical Carbonylation. (1998) (0)
- Pharmacogenomics of Flavin-containing Monooxygenase 3 involved in Trimethylamineuria (2009) (0)
- “In vivo” model for predicting organophosphate toxicity using humanized-liver chimeric mouse (2016) (0)
- Measurements of Streaming Neutrons on Nuclear Ship “Mutsu” by a Two-Detector-Method (1976) (0)
- Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital (2021) (0)
- ROLES OF HUMAN P450 ENZYMES IN DRUG OXIDATIONS USING RECOMBINANT P450S AND HUMAN LIVER MICROSOMES (1999) (0)
- The European Version of the Advanced Boiling Water Reactor – EU-ABWR (2013) (0)
- CHEMISTRY OF MIXED TRANSITION-METAL COMPLEXES PART 5, THE PREPARATION OF SEVERAL MIXED TRANSITION-METAL COMPLEXES WITH TWO MU-DIPHENYLPHOSPHIDE GROUPS (1973) (0)
- Biodegradation of Oil in Wastewater by Adding Fat-Degradating Yeast and Vitamins (2004) (0)
- Preparation method of oligopeptide adsorption carrier and method for assaying and removing lipolysaccharide using it (1991) (0)
- CO-Breathing Structure Change and Catalysis for Oxygenate Synthesis from CO / H 2 on Supported [ RuaC ] Clusters : Structural and Chemical Controls by Interstitial Carbido Carbon (2001) (0)
- A POLYMYXIN‐CLOTH ENZYME IMMUNOASSAY SYSTEM FOR SALMONELLA O SEROGROUP IDENTIFICATION (1994) (0)
- Expression Pro fi le of Hepatic Genes in Cynomolgus Macaques Bred in Cambodia , China , and Indonesia : Implications for Cytochrome P 450 Genes (2012) (0)
- Distribution of the CYP2A6 phenotypes of healthy Thai men and women using in vivo coumarin test (2002) (0)
- RECYCLING OF INCINERATION FLY ASH FROM MUNICIPAL REFUSE AS CEMENT RAW MATERIAL BY DESALINATION (1998) (0)
- 516 Effect of composite matrix on heat transfer and flow characteristics in regenerator of stirling engine (2014) (0)
- Metal Ion‐Bridged Intramolecular Stacking Interaction Between the Tryptophyl Residue and the Aromatic Heterocyclic Amine Within the Ternary Complex (1,10‐Phenanthroline)(L‐tryptophanato‐O,N)copper(II) Percholate‐Water (1/2.5): An X‐Ray Study. (1987) (0)
- Ternary Metal Complexes of Vitamin B6 Related Compounds. Crystal and Molecular Structures of Copper(II)-2,2′-Bipyridyl-Pyridoxic Acid and Copper(II)-2,2′-Bipyridyl-Pyridoxic Acid γ-Lactone Complexes. (1987) (0)
- CHEMISTRY OF MIXED TRANSITION-METAL COMPLEXES. VIII. PREPARATIONS OF Π-CYCLOPENTADIENYL(FERROCENYLCYCLOBUTADIENE)COBALT COMPLEXES AND 1,1′-(O-PHENYLENE)FERROCENES (1977) (0)
- Effect of CYP2C9 genotype for pharmacokinetics of efavirenz in vivo in cynomolgus monkeys (2017) (0)
- Interactions of Isocyanides with Transition-Metal Complexes. Part 30. X-Ray Crystal Structure of Pd2Cl2(2,6-Me2C6H3NC)2(py)2. Unusual C-N-C Bond Angles and IR Spectrum in Bridging Isocyanide Groups. (1987) (0)
- Effects of Screen and Sludge Circulations on the Performance of Domestic and Disposer Wastewater Treatment in Johkasou (2012) (0)
- COBALT METALLOCYCLES. III. THERMOLYSIS OF COBALTACYCLOPENTADIENE COMPLEXES (1978) (0)
- Immobilization of glucoamylase on naphthyl cotton cloth (1985) (0)
- Evaluation of Environmental Load Mitigation by Overseas Promotion of Decentralised Wastewater Treatment Facilities (2020) (0)
- Mutations of flavin-containing monooxygenase 3 (FMO3) gene in Japanese cohorts (2019) (0)
- A case with major depression showing marked tremor during treatments with amoxapine, paroxetine and diltiazem (2004) (0)
- SYNTHESES AND CRYSTAL STRUCTURES OF THE RUTHENIUM CARBIDOCARBONYL CLUSTERSRU5C(CO)11(MU -BR)2(ETA 3-C3H5)(MU -ETA 3-THETA 3H5), RU5C(CO)13I(MU -I)(MU -H2-COME)-, RU5C(CO)14(MU -BR)2 AND RU6C(CO)16(MU -BR)- WITH NOVEL METAL F RAMEWORKS (1995) (0)
- Interactions of Isocyanides with Transition Metal Complexes. Part 32. Reactions of Cyclobutenedione and Cyclopentenetrione with Zero-Valent Nickel Triad Complexes of Isocyanide. X-Ray Crystal Structures of (3-4-η-3,4-Diphenylcyclobut- (1987) (0)
- Molecular cloning and tissue distribution of marmoset thiopurine S-methyltransferase. (2020) (0)
- Reactions of Cobaltacyclopentadiene Complexes with Organic Azides Directed Toward Synthesis of Highly-Substituted Pyrroles. (1990) (0)
- Performance index and rational maintenance method of cut slope in consideration of long-term deterioration (2017) (0)
- SYNTHESIS OF 2-OXO-1,2-DIHYDROPYRIDINES BY THE REACTION OF COBALTACYCLOPENTADIENE COMPLEXES WITH ISOCYANATES (1977) (0)
- Molecular Biological Analysis of AOB in Wastewater Treatment Process with Flocculant (2004) (0)
- A TEMPERATURE HYSTERESIS EFFECT IN ON-SITE DOMESTIC WASTEWATER TREATMENT FACILITIES (2020) (0)
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What Schools Are Affiliated With Hiroshi Yamazaki?
Hiroshi Yamazaki is affiliated with the following schools:
