Hirotaka Watada
#161,840
Most Influential Person Now
Researcher
Hirotaka Watada's AcademicInfluence.com Rankings
Hirotaka Watadacomputer-science Degrees
Computer Science
#9379
World Rank
#9852
Historical Rank
Machine Learning
#4086
World Rank
#4135
Historical Rank
Artificial Intelligence
#4426
World Rank
#4487
Historical Rank
Database
#6345
World Rank
#6577
Historical Rank
Download Badge
Computer Science
Hirotaka Watada's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
Similar Degrees You Can Earn
Why Is Hirotaka Watada Influential?
(Suggest an Edit or Addition)Hirotaka Watada's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. (2008) (581)
- Inhibition of Monocyte Adhesion to Endothelial Cells and Attenuation of Atherosclerotic Lesion by a Glucagon-like Peptide-1 Receptor Agonist, Exendin-4 (2010) (466)
- Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. (1994) (418)
- Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells. (1997) (338)
- Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients. (2005) (318)
- Gut Dysbiosis and Detection of “Live Gut Bacteria” in Blood of Japanese Patients With Type 2 Diabetes (2014) (313)
- Serotonin Regulates Pancreatic β-Cell Mass during Pregnancy (2010) (305)
- Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis (2017) (284)
- Regulation of the pancreatic pro-endocrine gene neurogenin3. (2001) (276)
- A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B (2010) (261)
- The emerging role of autophagy in the pathophysiology of diabetes mellitus (2011) (251)
- The Human Glucokinase Gene β-Cell-Type Promoter: An Essential Role of Insulin Promoter Factor 1/PDX-1 in Its Activation in HIT-T15 Cells (1996) (236)
- Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells (2003) (234)
- PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin (1996) (219)
- The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance. (2013) (207)
- Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial (2019) (188)
- Oxidative Stress Induces Nucleo-Cytoplasmic Translocation of Pancreatic Transcription Factor PDX-1 Through Activation of c-Jun NH2-terminal Kinase (2003) (177)
- Comparison of glycated albumin (GA) and glycated hemoglobin (HbA1c) in type 2 diabetic patients: usefulness of GA for evaluation of short-term changes in glycemic control. (2007) (172)
- Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined Phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study (2014) (169)
- Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy. (2014) (155)
- Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice. (2013) (155)
- Eicosapentaenoic acid reduces the progression of carotid intima-media thickness in patients with type 2 diabetes. (2007) (150)
- Repetitive Fluctuations in Blood Glucose Enhance Monocyte Adhesion to the Endothelium of Rat Thoracic Aorta (2006) (150)
- Genome-wide association study identifies three novel loci for type 2 diabetes. (2014) (149)
- Dobutamine stress echocardiography predicts reversible dysfunction and quantitates the extent of irreversibly damaged myocardium after reperfusion of anterior myocardial infarction. (1994) (148)
- Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes (2016) (136)
- Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program) (2018) (133)
- Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy (2013) (133)
- PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells. (2002) (125)
- Neurogenin3 and Hepatic Nuclear Factor 1 Cooperate in Activating Pancreatic Expression of Pax4* (2003) (125)
- Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects. (2007) (125)
- PAX6 mutation as a genetic factor common to aniridia and glucose intolerance. (2002) (121)
- Endothelial PGC-1α mediates vascular dysfunction in diabetes. (2014) (118)
- Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) (2015) (114)
- Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE) (2016) (111)
- Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. (2010) (108)
- Linagliptin monotherapy provides superior glycaemic control versus placebo or voglibose with comparable safety in Japanese patients with type 2 diabetes: a randomized, placebo and active comparator‐controlled, double‐blind study (2012) (107)
- Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial (2018) (106)
- The polymorphism of manganese superoxide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients (2003) (106)
- Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase. (2003) (106)
- Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury. (2011) (104)
- Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription. (1996) (103)
- A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. (2012) (103)
- Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes. (2002) (101)
- In Vivo and In Vitro Inhibition of Monocyte Adhesion to Endothelial Cells and Endothelial Adhesion Molecules by Eicosapentaenoic Acid (2008) (99)
- Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins. (2000) (98)
- Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan (1997) (95)
- Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis (2018) (93)
- Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. (2003) (89)
- Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice. (2006) (89)
- Impact of Oxidative Stress and Peroxisome Proliferator–Activated Receptor γ Coactivator-1α in Hepatic Insulin Resistance (2008) (87)
- Combination of the Framingham Risk Score and Carotid Intima-Media Thickness Improves the Prediction of Cardiovascular Events in Patients With Type 2 Diabetes (2011) (85)
- RANTES promoter genotype is associated with diabetic nephropathy in type 2 diabetic subjects. (2003) (83)
- Neurogenin3 activates the islet differentiation program while repressing its own expression. (2004) (82)
- Transcriptional and Translational Regulation of β-Cell Differentiation Factor Nkx6.1* (2000) (77)
- Autoregulation and Maturity Onset Diabetes of the Young Transcription Factors Control the Human PAX4 Promoter* (2000) (77)
- Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. (2004) (75)
- Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study (2017) (75)
- Distinct Gene Expression Programs Function in Progenitor and Mature Islet Cells* (2003) (75)
- Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials (2014) (74)
- Comparison of Effects of Olmesartan and Telmisartan on Blood Pressure and Metabolic Parameters in Japanese Early-Stage Type-2 Diabetics with Hypertension (2008) (73)
- A randomized controlled trial of 130 g/day low-carbohydrate diet in type 2 diabetes with poor glycemic control. (2017) (73)
- Minireview: Autophagy in pancreatic β-cells and its implication in diabetes. (2015) (71)
- Impaired insulin secretion in vivo but enhanced insulin secretion from isolated islets in pancreatic beta cell-specific vascular endothelial growth factor-A knock-out mice (2007) (70)
- Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice. (2007) (70)
- Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects. (2008) (70)
- Expression of Heparin-binding Epidermal Growth Factor-like Growth Factor during Pancreas Development (1997) (69)
- Association of New Loci Identified in European Genome-Wide Association Studies with Susceptibility to Type 2 Diabetes in the Japanese (2011) (69)
- Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1. (2004) (68)
- Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas (1999) (66)
- Protein Kinase Cδ Plays a Non-redundant Role in Insulin Secretion in Pancreatic β Cells* (2007) (66)
- Golgi membrane‐associated degradation pathway in yeast and mammals (2016) (63)
- Temporary hyperglycaemia provokes monocyte adhesion to endothelial cells in rat thoracic aorta (2005) (62)
- β-Cell Differentiation Factor Nkx6.1 Contains Distinct DNA Binding Interference and Transcriptional Repression Domains* (2000) (60)
- Safety and efficacy of once‐weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial (2018) (59)
- ELMO1 increases expression of extracellular matrix proteins and inhibits cell adhesion to ECMs. (2006) (59)
- Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells (1999) (57)
- Nateglinide Reduces Carotid Intima-Media Thickening in Type 2 Diabetic Patients Under Good Glycemic Control (2007) (57)
- Exendin-4 improves β-cell function in autophagy-deficient β-cells. (2013) (57)
- Treatment of type 2 diabetes mellitus worldwide: Baseline patient characteristics in the global DISCOVER study. (2019) (57)
- The role of autophagy in pancreatic β-cell and diabetes (2009) (57)
- Prevalence of Abnormal Glucose Metabolism and Insulin Resistance Among Subtypes of Ischemic Stroke in Japanese Patients (2009) (57)
- Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. (2009) (55)
- Long‐term, but not short‐term high‐fat diet induces fiber composition changes and impaired contractile force in mouse fast‐twitch skeletal muscle (2017) (55)
- Association of Methylenetetrahydrofolate Reductase Gene Polymorphism With Carotid Arterial Wall Thickening and Myocardial Infarction Risk in NIDDM (1997) (52)
- The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. (2004) (52)
- Replication Study for the Association Between Four Loci Identified by a Genome-Wide Association Study on European American Subjects With Type 1 Diabetes and Susceptibility to Diabetic Nephropathy in Japanese Subjects With Type 2 Diabetes (2010) (52)
- Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m2. (2016) (51)
- Exercise-induced increase in IL-6 level enhances GLUT4 expression and insulin sensitivity in mouse skeletal muscle. (2016) (51)
- Acarbose, an alpha-glucosidase inhibitor, improves endothelial dysfunction in Goto-Kakizaki rats exhibiting repetitive blood glucose fluctuation. (2006) (49)
- Role of VEGF-A in pancreatic beta cells. (2010) (48)
- Replication Study for the Association of 9 East Asian GWAS-Derived Loci with Susceptibility to Type 2 Diabetes in a Japanese Population (2013) (48)
- The role of autophagy in pancreatic beta-cell and diabetes. (2009) (48)
- Morningness–eveningness questionnaire score and metabolic parameters in patients with type 2 diabetes mellitus (2014) (47)
- Poor sleep quality is associated with increased arterial stiffness in Japanese patients with type 2 diabetes mellitus (2015) (47)
- Pancreatic islet cells express BST-1, a CD38-like surface molecule having ADP-ribosyl cyclase activity. (1996) (46)
- Glucose Monitoring After Fruit Peeling: Pseudohyperglycemia When Neglecting Hand Washing Before Fingertip Blood Sampling (2011) (46)
- The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus (2016) (45)
- PAX 6 Mutation as a Genetic Factor Common to Aniridia and Glucose Intolerance (2001) (45)
- Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor linagliptin: a 4-week multicenter, randomized, double-blind, placebo-controlled phase IIa study in Japanese type 2 diabetes patients. (2011) (44)
- p38 MAPK Is Involved in Activin A- and Hepatocyte Growth Factor-mediated Expression of Pro-endocrine Gene Neurogenin 3 in AR42J-B13 Cells* (2003) (44)
- Towards an improved global understanding of treatment and outcomes in people with type 2 diabetes: Rationale and methods of the DISCOVER observational study program. (2017) (44)
- Regulation of the Pancreatic Pro-Endocrine Gene (2001) (43)
- Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice (2009) (43)
- The Arg192 isoform of paraoxonase with low sarin-hydrolyzing activity is dominant in the Japanese (1997) (42)
- Coronary microvascular function is independently associated with left ventricular filling pressure in patients with type 2 diabetes mellitus (2015) (42)
- Autophagy in health and disease. 4. The role of pancreatic beta-cell autophagy in health and diabetes. (2010) (42)
- Preferable effect of pravastatin compared to atorvastatin on beta cell function in Japanese early-state type 2 diabetes with hypercholesterolemia. (2007) (42)
- Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression (2017) (42)
- A Single Nucleotide Polymorphism within DUSP9 Is Associated with Susceptibility to Type 2 Diabetes in a Japanese Population (2012) (41)
- Masked hypertension, endothelial dysfunction, and arterial stiffness in type 2 diabetes mellitus: a pilot study. (2012) (41)
- Effects of Pioglitazone for Secondary Stroke Prevention in Patients with Impaired Glucose Tolerance and Newly Diagnosed Diabetes: The J-SPIRIT Study. (2015) (40)
- Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial (2016) (40)
- Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension. (2017) (40)
- Relationship between olfactory dysfunction and cognitive impairment in elderly patients with type 2 diabetes mellitus. (2014) (39)
- Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells. (1997) (38)
- White Matter Alteration in Metabolic Syndrome (2013) (37)
- Effect of cilostazol, a phosphodiesterase inhibitor, on carotid IMT in Japanese type 2 diabetic patients. (2004) (37)
- Glucose fluctuation on the progression of diabetic macroangiopathy--new findings from monocyte adhesion to endothelial cells. (2007) (37)
- Strict glycemic control ameliorates the increase of carotid IMT in patients with type 2 diabetes. (2006) (37)
- Effects of pioglitazone on macrovascular events in patients with type 2 diabetes mellitus at high risk of stroke: the PROFIT-J study. (2014) (36)
- Influencing factors on cardiac structure and function beyond glycemic control in patients with type 2 diabetes mellitus (2013) (36)
- Repetitive hypoglycaemia increases serum adrenaline and induces monocyte adhesion to the endothelium in rat thoracic aorta (2011) (35)
- Comparison of effects of pitavastatin and atorvastatin on glucose metabolism in type 2 diabetic patients with hypercholesterolemia (2013) (35)
- Amelioration of glucose tolerance by hepatic inhibition of nuclear factor κB in db/db mice (2006) (35)
- Chemotactic cytokine receptor 5 (CCR5) gene promoter polymorphism (59029A/G) is associated with diabetic nephropathy in Japanese patients with type 2 diabetes: a 10-year longitudinal study. (2006) (35)
- Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis (2016) (35)
- Type 2 Diabetes: When Does It Start? (2018) (34)
- Exercise-induced enhancement of insulin sensitivity is associated with accumulation of M2-polarized macrophages in mouse skeletal muscle. (2013) (34)
- Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population (2011) (33)
- A new En face method is useful to quantitate endothelial damage in vivo. (2003) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Expression of CD38 gene, but not of mitochondrial glycerol-3-phosphate dehydrogenase gene, is impaired in pancreatic islets of GK rats. (1995) (33)
- Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population. (2013) (33)
- Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells. (2007) (33)
- Determinants of intramyocellular lipid accumulation after dietary fat loading in non‐obese men (2010) (32)
- Presence of alpha-smooth muscle actin-positive endothelial cells in the luminal surface of adult aorta. (2009) (32)
- Pdx1 Expression in Irs2-deficient Mouse β-Cells Is Regulated in a Strain-dependent Manner* (2003) (32)
- Short-term effects of dietary fat on intramyocellular lipid in sprinters and endurance runners. (2008) (32)
- Neurogenin 3 is a key transcription factor for differentiation of the endocrine pancreas. (2004) (32)
- Incidence and time course of left ventricular dilation in the early convalescent stage of reperfused anterior wall acute myocardial infarction. (1994) (32)
- Linagliptin provides effective, well‐tolerated add‐on therapy to pre‐existing oral antidiabetic therapy over 1 year in Japanese patients with type 2 diabetes (2013) (32)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Efficacy of acarbose in different geographical regions of the world: analysis of a real‐life database (2015) (31)
- Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes. (2009) (30)
- Acute onset and worsening of diabetes concurrent with administration of statins. (2005) (30)
- Accumulation of Somatic Mutation in Mitochondrial DNA and Atherosclerosis in Diabetic Patients (2004) (30)
- Functional subdivisions of the hypothalamus using areal parcellation and their signal changes related to glucose metabolism (2017) (30)
- β-cell autophagy: A novel mechanism regulating β-cell function and mass- Lessons from β-cell-specific Atg7-deficient mice (2009) (30)
- Increased intramyocellular lipid/impaired insulin sensitivity is associated with altered lipid metabolic genes in muscle of high responders to a high-fat diet. (2016) (30)
- Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second‐line therapy: Results from the global DISCOVER study programme (2019) (29)
- Clinical Utility of Carotid Ultrasonography in the Prediction of Cardiovascular Events in Patients with Diabetes: A Combined Analysis of Data Obtained in Five Longitudinal Studies (2018) (29)
- Relationship between dietary patterns and risk factors for cardiovascular disease in patients with type 2 diabetes mellitus: a cross-sectional study (2015) (28)
- Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52‐week data from the PROVIDE study (2019) (28)
- Improvement of quality of life through glycemic control by liraglutide, a GLP-1 analog, in insulin-naive patients with type 2 diabetes mellitus: the PAGE1 study (2017) (28)
- Polymorphism of the solute carrier family 12 (sodium/chloride transporters) member 3, SLC12A3, gene at exon 23 (+78G/A: Arg913Gln) is associated with elevation of urinary albumin excretion in Japanese patients with type 2 diabetes: a 10-year longitudinal study (2005) (28)
- Therapeutic effectiveness of potassium iodine in drug-naïve patients with Graves’ disease: a single-center experience (2014) (28)
- Morningness–eveningness questionnaire score correlates with glycated hemoglobin in middle‐aged male workers with type 2 diabetes mellitus (2013) (27)
- A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes (2018) (27)
- NEUROD1‐deficient diabetes (MODY6): Identification of the first cases in Japanese and the clinical features (2018) (27)
- Association between Myocardial Triglyceride Content and Cardiac Function in Healthy Subjects and Endurance Athletes (2013) (26)
- Long‐term safety of linagliptin monotherapy in Japanese patients with type 2 diabetes (2013) (26)
- Effects of Synbiotic Supplementation on Chronic Inflammation and the Gut Microbiota in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Study (2021) (26)
- Effects of metformin on peripheral insulin sensitivity and intracellular lipid contents in muscle and liver of overweight Japanese subjects (2008) (26)
- 2-Methoxyestradiol reduces monocyte adhesion to aortic endothelial cells in ovariectomized rats. (2007) (24)
- Effect of AST-120 on Endothelial Dysfunction in Adenine-Induced Uremic Rats (2014) (24)
- Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis. (2018) (24)
- A Single Nucleotide Polymorphism in KCNQ1 Is Associated With Susceptibility to Diabetic Nephropathy in Japanese Subjects With Type 2 Diabetes (2010) (24)
- Association of C-reactive protein with early-stage carotid atherosclerosis in Japanese patients with early-state type 2 diabetes mellitus. (2006) (24)
- Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice (2015) (23)
- Therapeutic efficacy of mitiglinide combined with once daily insulin glargine after switching from multiple daily insulin regimen of aspart insulin and glargine in patients with type 2 diabetes mellitus. (2006) (23)
- Tofogliflozin does not delay progression of carotid atherosclerosis in patients with type 2 diabetes: a prospective, randomized, open-label, parallel-group comparative study (2020) (23)
- One year follow-up after a randomized controlled trial of a 130 g/day low-carbohydrate diet in patients with type 2 diabetes mellitus and poor glycemic control (2017) (23)
- Insulin and nateglinide reduce monocyte adhesion to endothelial cells in Goto-Kakizaki rats exhibiting repetitive blood glucose fluctuation. (2006) (23)
- Carotid intima-media thickness progression predicts cardiovascular events in Japanese patients with type 2 diabetes. (2013) (22)
- Ubiquitous, but variable, expression of two alternatively spliced mRNAs encoding mouse homologues of transcription factors E47 and E12. (1995) (22)
- Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients. (2010) (22)
- Correlates of insulin clearance in apparently healthy non-obese Japanese men (2017) (22)
- Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan (2020) (22)
- Acarbose reduces body weight irrespective of glycemic control in patients with diabetes: results of a worldwide, non-interventional, observational study data pool. (2016) (22)
- SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell* (2015) (21)
- Expression mechanism of tryptophan hydroxylase 1 in mouse islets during pregnancy. (2015) (21)
- Differences between rosuvastatin and atorvastatin in lipid-lowering action and effect on glucose metabolism in Japanese hypercholesterolemic patients with concurrent diabetes. Lipid-lowering with highly potent statins in hyperlipidemia with type 2 diabetes patients (LISTEN) study –. (2014) (21)
- Prevalence of Amiodarone-Induced Thyrotoxicosis and Associated Risk Factors in Japanese Patients (2014) (21)
- Hypoglycemia following a nateglinide overdose in a suicide attempt. (2005) (21)
- Identification and comparison of insulin pharmacokinetics injected with a new 4‐mm needle vs 6‐ and 8‐mm needles accounting for endogenous insulin and C‐peptide secretion kinetics in non‐diabetic adult males (2013) (21)
- Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity. (2019) (20)
- Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance. (2009) (20)
- Quality‐Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells (2018) (20)
- Anti-oxidative effect of fluvastatin in hyperlipidemic type 2 diabetic patients. (2005) (20)
- Effects of sitagliptin on ectopic fat contents and glucose metabolism in type 2 diabetic patients with fatty liver: A pilot study (2014) (20)
- Lipoprotein-X in cholestatic patients causes xanthomas and promotes foam cell formation in human macrophages. (2017) (20)
- Rationale and Design for the J-DISCOVER Study: DISCOVERing the Treatment Reality of Type 2 Diabetes in a Real-World Setting in Japan—A Protocol (2017) (20)
- Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study (2019) (20)
- Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis (2018) (19)
- Responsiveness of insulin-induced cardiac sympathetic nerve activation associates with blood pressure regulation in diabetics. (2003) (19)
- Attempted suicide with liraglutide overdose did not induce hypoglycemia. (2013) (19)
- Preserving expression of Pdx1 improves β-cell failure in diabetic mice. (2017) (19)
- Effect of tofogliflozin on arterial stiffness in patients with type 2 diabetes: prespecified sub-analysis of the prospective, randomized, open-label, parallel-group comparative UTOPIA trial (2021) (19)
- Age-Related Changes in Relaxation Times, Proton Density, Myelin, and Tissue Volumes in Adult Brain Analyzed by 2-Dimensional Quantitative Synthetic Magnetic Resonance Imaging (2020) (19)
- Efficacy and safety of modified Yale insulin infusion protocol in Japanese diabetic patients after open-heart surgery. (2008) (19)
- Efficacy and safety of once daily gliclazide (20 mg/day) compared with nateglinide. (2004) (19)
- Effect of sitagliptin on tissue characteristics of the carotid wall in patients with type 2 diabetes: a post hoc sub-analysis of the sitagliptin preventive study of intima-media thickness evaluation (SPIKE) (2018) (18)
- Defective autophagy in vascular smooth muscle cells enhances atherosclerotic plaque instability. (2018) (18)
- Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study (2018) (18)
- Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan (2021) (18)
- Dysfunction of muscle contraction with impaired intracellular Ca2+ handling in skeletal muscle and the effect of exercise training in male db/db mice. (2019) (18)
- Characteristics of hepatic insulin‐sensitive nonalcoholic fatty liver disease (2017) (18)
- Efficacy and Safety of 1:1 Fixed-Ratio Combination of Insulin Glargine and Lixisenatide Versus Lixisenatide in Japanese Patients With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial (2020) (18)
- Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan (2021) (18)
- Combination treatment of db/db mice with exendin‐4 and gastrin preserves β‐cell mass by stimulating β‐cell growth and differentiation (2010) (17)
- Rationale, design, and baseline characteristics of a clinical trial for prevention of atherosclerosis in patients with insulin-treated type 2 diabetes mellitus using DPP-4 inhibitor: the Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE) (2014) (17)
- Glycaemic control in patients with type 2 diabetes initiating second‐line therapy: Results from the global DISCOVER study programme (2019) (17)
- Linagliptin and cardiorenal outcomes in Asians with type 2 diabetes mellitus and established cardiovascular and/or kidney disease: subgroup analysis of the randomized CARMELINA® trial (2019) (17)
- Effects of changes in basal/total daily insulin ratio in type 2 diabetes patients on intensive insulin therapy including insulin glargine (JUN-LAN Study 6). (2008) (17)
- Neurogenin 3 and Hepatic Nuclear Factor 1 cooperate in activating pancreatic expression of Pax 4 (2003) (17)
- Associations between continuous glucose monitoring-derived metrics and arterial stiffness in Japanese patients with type 2 diabetes (2021) (17)
- Impact of insulin resistance on enhanced monocyte adhesion to endothelial cells and atherosclerogenesis independent of LDL cholesterol level. (2010) (16)
- Rationale, design, and baseline characteristics of a trial for the prevention of diabetic atherosclerosis using a DPP-4 inhibitor: the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). (2013) (16)
- Combined expression of transcription factors induces AR42J-B13 cells to differentiate into insulin-producing cells. (2008) (16)
- Type 2 Diabetes and Bacteremia (2017) (16)
- Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men (2019) (16)
- Impaired insulin clearance as a cause rather than a consequence of insulin resistance (2017) (16)
- Efficacy and Safety of Sitagliptin in Japanese Patients With Type 2 Diabetes (2015) (16)
- Association between expression of FABPpm in skeletal muscle and insulin sensitivity in intramyocellular lipid-accumulated nonobese men. (2014) (16)
- A chronic high-fat diet exacerbates contractile dysfunction with impaired intracellular Ca2+ release capacity in the skeletal muscle of aged mice. (2020) (16)
- Dose-dependent requirement of patched homologue 1 in mouse pancreatic beta cell mass (2008) (15)
- Association between atherosclerosis and newly classified chronic kidney disease stage for Japanese patients with type 2 diabetes. (2009) (15)
- Effect of sitagliptin on plaque changes in coronary artery following acute coronary syndrome in diabetic patients: The ESPECIAL-ACS study. (2017) (15)
- Impact of whole body irradiation and vascular endothelial growth factor-A on increased beta cell mass after bone marrow transplantation in a mouse model of diabetes induced by streptozotocin (2008) (15)
- Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy (2017) (15)
- Cutoff value of thyroid uptake of (99m)Tc-pertechnetate to discriminate between Graves' disease and painless thyroiditis: a single center retrospective study. (2016) (15)
- Guidelines for clinical evaluation of chronic kidney disease (2018) (15)
- Impaired peripheral insulin sensitivity in non‐obese Japanese patients with type 2 diabetes mellitus and fatty liver (2017) (15)
- Superior HbA1c control with the fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with a maximum dose of 50 units of insulin degludec in Japanese individuals with type 2 diabetes in a phase 3, double‐blind, randomized trial (2019) (14)
- Angiotensin II receptor blocker provides pancreatic β-cell protection independent of blood pressure lowering in diabetic db/db mice (2007) (14)
- Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes (2015) (14)
- Sequential introduction and dosage balance of defined transcription factors affect reprogramming efficiency from pancreatic duct cells into insulin-producing cells. (2014) (14)
- Chronological Analysis With Fluorescent Timer Reveals Unique Features of Newly Generated β-Cells (2014) (14)
- Diffusional kurtosis imaging analysis in patients with hypertension (2014) (14)
- Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies (2016) (13)
- Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study (2017) (13)
- Long-term effect of combination therapy with mitiglinide and once daily insulin glargine in patients who were successfully switched from intensive insulin therapy in short-term study. (2007) (13)
- Glucagon like Peptide-1 and atherosclerosis. (2012) (13)
- Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT‐5): 52‐week results from a randomized, open‐label, phase III clinical trial (2019) (13)
- Sustained expression of GLP-1 receptor differentially modulates β-cell functions in diabetic and nondiabetic mice. (2016) (13)
- N-(carboxymethyl)valine residues in hemoglobin (CMV-Hb) reflect accumulation of oxidative stress in diabetic patients. (2005) (13)
- Protocol of a Prospective Observational Study on the Relationship Between Glucose Fluctuation and Cardiovascular Events in Patients with Type 2 Diabetes (2019) (13)
- Pharmacokinetics and pharmacodynamics of dapagliflozin in combination with insulin in Japanese patients with type 1 diabetes (2018) (13)
- Increased expression of ERp57/GRP58 is protective against pancreatic beta cell death caused by autophagic failure. (2014) (13)
- Long-term efficacy of insulin glargine after switching from NPH insulin as intensive replacement of basal insulin in Japanese diabetes mellitus. Comparison of efficacy between type 1 and type 2 diabetes (JUN-LAN Study 1.2). (2007) (12)
- Insulin exocytosis in Goto-Kakizaki rat beta-cells subjected to long-term glinide or sulfonylurea treatment. (2008) (12)
- Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure. (2007) (12)
- In-Depth Insight Into the Mechanisms of Cardiac Dysfunction in Patients With Type 1 Diabetes Mellitus Using Layer-Specific Strain Analysis. (2019) (12)
- Overexpression of acetyl-coenzyme A carboxylase beta increases proinflammatory cytokines in cultured human renal proximal tubular epithelial cells (2010) (12)
- Efficacy and safety of nateglinide plus vildagliptin combination therapy compared with switching to vildagliptin in type 2 diabetes patients inadequately controlled with nateglinide (2013) (12)
- Associations between continuous glucose monitoring-derived metrics and diabetic retinopathy and albuminuria in patients with type 2 diabetes (2020) (11)
- Plasma glucagon levels measured by sandwich ELISA are correlated with impaired glucose tolerance in type 2 diabetes. (2020) (11)
- Replication study for the association of rs391300 in SRR and rs17584499 in PTPRD with susceptibility to type 2 diabetes in a Japanese population (2012) (11)
- Effect of maternal high-fat diet on pancreatic beta cells of the offspring (2012) (11)
- Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study (2017) (11)
- An Investigation of Water Diffusivity Changes along the Perivascular Space in Elderly Subjects with Hypertension (2021) (11)
- Mutation of the Pax6 gene causes impaired glucose-stimulated insulin secretion (2004) (11)
- Clinical significance and management of insomnia (2011) (11)
- Ex vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing (2021) (11)
- Characteristics of Glucose Metabolism in Underweight Japanese Women (2018) (11)
- Effect of Repetitive Glucose Spike and Hypoglycaemia on Atherosclerosis and Death Rate in Apo E-Deficient Mice (2015) (11)
- Effect of treatment guidance using a retrospective continuous glucose monitoring system on glycaemic control in outpatients with type 2 diabetes mellitus: A randomized controlled trial* (2015) (11)
- Characteristics of Japanese subjects who progress from normal to impaired glucose tolerance. Longitudinal study excluding changes in body weight. (2005) (10)
- Relationship between dietary pattern and cognitive function in elderly patients with type 2 diabetes mellitus (2015) (10)
- Relationships between lifestyle patterns and cardio-renal-metabolic parameters in patients with type 2 diabetes mellitus: A cross-sectional study (2017) (10)
- p 38 MAPK Is Involved in Activin Aand Hepatocyte Growth Factor-mediated Expression of Pro-endocrine Gene Neurogenin 3 in AR 42 JB 13 Cells * (2003) (10)
- Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study (2015) (10)
- Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study (2017) (10)
- Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients. (2010) (10)
- Incidence Rates and Predictors of Microvascular and Macrovascular Complications in Patients with Type 2 Diabetes: Results from the Longitudinal Global DISCOVER Study. (2021) (10)
- Management of home blood pressure by amlodipine combined with angiotensin II receptor blocker in type 2 diabetes. (2012) (10)
- Repetitive postprandial hypertriglyceridemia induces monocyte adhesion to aortic endothelial cells in Goto-Kakizaki rats. (2008) (10)
- Comparison of insulin lispro mix 25 with insulin lispro mix 50 as an insulin starter in Asian patients with type 2 diabetes: a phase 4, open‐label, randomized trial (CLASSIFY study) (2017) (9)
- Angiotensin II type 1 receptor blocker reduces monocyte adhesion to endothelial cells in spontaneously hypertensive rats. (2007) (9)
- Effects of blood flow restriction on muscle size and gene expression in muscle during immobilization: A pilot study (2020) (9)
- Dose-Dependent Effect of Sitagliptin on Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Post Hoc Analysis (2017) (9)
- IDegLira Improves Glycemic Control in Japanese Patients with Uncontrolled Type 2 Diabetes on Premixed Insulin Therapy (2019) (9)
- Acarbose improves glycemic control and reduces body weight: Subanalysis data of South Asia region (2013) (9)
- Efficacy and safety of the G protein‐coupled receptor 119 agonist DS‐8500a in Japanese type 2 diabetes mellitus patients with inadequate glycemic control on sitagliptin: A phase 2 randomized placebo‐controlled study (2018) (9)
- Changes in carotid intima‐media thickening in patients with type 2 diabetes mellitus: Subanalysis of the Sitagliptin Preventive Study of Intima‐Media Thickness Evaluation (2017) (9)
- Relationships Among Conventional Cardiovascular Risk Factors and Lifestyle Habits With Arterial Stiffness in Type 2 Diabetic Patients (2017) (9)
- 2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice (2010) (9)
- Preliminary report: mitochondrial DNA 5178 polymorphism in male elite Japanese endurance runners. (2010) (9)
- Biphasic changes in β-cell mass around parturition are accompanied by increased serotonin production (2020) (9)
- Effects of linagliptin monotherapy compared with voglibose on postprandial blood glucose responses in Japanese patients with type 2 diabetes: Linagliptin Study of Effects on Postprandial blood glucose (L-STEP). (2016) (9)
- Evaluation of myocardial triglyceride accumulation assessed on 1H-magnetic resonance spectroscopy in apparently healthy Japanese subjects. (2015) (8)
- Global patterns of comprehensive cardiovascular risk factor control in patients with type 2 diabetes mellitus: Insights from the DISCOVER study (2020) (8)
- IRS-2 deficiency in macrophages promotes their accumulation in the vascular wall. (2011) (8)
- Alpha-glucosidase inhibitor, acarbose, improves glycamic control and reduces body weight in type 2 diabetes: Findings on indian patients from the pooled data analysis (2013) (8)
- Effect of sulfonylureas on switching to insulin therapy (twice-daily biphasic insulin aspart 30): comparison of twice-daily biphasic insulin aspart 30 with or without glimepiride in type 2 diabetic patients poorly controlled with sub-maximal glimepiride. (2009) (8)
- Heterogeneity of autophagic status in pancreatic β cells under metabolic stress. (2018) (8)
- Roles of autophagy in pancreatic β-cell function and type 2 diabetes (2011) (8)
- The Effect of Sitagliptin on the Regression of Carotid Intima-Media Thickening in Patients with Type 2 Diabetes Mellitus: A Post Hoc Analysis of the Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (2017) (8)
- Relationship between frequency of hypoglycemic episodes and changes in carotid atherosclerosis in insulin-treated patients with type 2 diabetes mellitus (2017) (8)
- Evanescent Hyperechoic Changes After Fine‐Needle Aspiration Biopsy of the Thyroid in a Series With a Low Overall Prevalence of Complications (2016) (8)
- G protein‐coupled receptor 119 agonist DS‐8500a effects on pancreatic β‐cells in Japanese type 2 diabetes mellitus patients (2018) (8)
- Association Between Visceral Fat Accumulation and Exercise Tolerance in Non-Obese Subjects Without Diabetes (2018) (8)
- Efficacy and adverse effects of nateglinide in early type 2 diabetes. Comparison with voglibose in a cross-over study. (2006) (8)
- Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/E12. (2006) (8)
- Transforming growth factor β1 T868C gene polymorphism is associated with cerebral infarction in Japanese patients with type 2 diabetes. (2011) (7)
- Comparison of sitagliptin with nateglinide on postprandial glucose and related hormones in drug-naïve Japanese patients with type 2 diabetes mellitus: A pilot study (2015) (7)
- Efficacy of pioglitazone on glycemic control and carotid intima‐media thickness in type 2 diabetes patients with inadequate insulin therapy (2010) (7)
- Global use of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. Results from DISCOVER (2021) (7)
- Associations of continuous glucose monitoring-assessed glucose variability with intima-media thickness and ultrasonic tissue characteristics of the carotid arteries: a cross-sectional analysis in patients with type 2 diabetes (2021) (7)
- Combination therapy of miglitol and insulin in type 1 diabetes mellitus patients (2010) (7)
- Repetitive hypoglycemia increases circulating adrenaline level with resultant worsening of intimal thickening after vascular injury in male Goto-Kakizaki rat carotid artery. (2014) (7)
- Suppression of STAT3 signaling promotes cellular reprogramming into insulin-producing cells induced by defined transcription factors (2018) (7)
- Reliability and validity of the Japanese version of the Diabetes Quality-Of-Life questionnaire for Japanese patients with type 2 diabetes mellitus (2014) (7)
- Comparison of effects of cilnidipine and azelnidipine on blood pressure, heart rate and albuminuria in type 2 diabetics with hypertension: A pilot study (2012) (7)
- Higher C-Peptide Level During Glucose Clamp Is Associated With Muscle Insulin Resistance in Nonobese Japanese Men (2019) (7)
- Continuous glucose monitoring system: Is it really accurate, safe and clinically useful? (2012) (6)
- Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND): study design and baseline characteristics of patients with type 2 diabetes newly initiating oral antidiabetic drug monotherapy in Japan (2020) (6)
- Normal pancreatic β-cell function in mice with RIP-Cre-mediated inactivation of p62/SQSTM1. (2017) (6)
- Clinical characteristics influencing the effectiveness of metformin on Japanese type 2 diabetes receiving sulfonylureas. (2007) (6)
- Efficacy and safety of imeglimin add‐on to insulin monotherapy in Japanese patients with type 2 diabetes (TIMES 3): A randomized, double‐blind, placebo‐controlled phase 3 trial with a 36‐week open‐label extension period (2021) (6)
- Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population (2013) (6)
- Prevalence and features of impaired glucose tolerance in young underweight Japanese women. (2021) (6)
- Inappropriate intensification of glucose-lowering treatment in older patients with type 2 diabetes: the global DISCOVER study (2021) (6)
- Shape of the glucose response curve during an oral glucose tolerance test is associated with insulin clearance and muscle insulin sensitivity in healthy non‐obese men (2020) (6)
- Olfactory dysfunction predicts the development of dementia in older patients with type 2 diabetes. (2021) (6)
- Everolimus Directly Suppresses Insulin Secretion Independently of Cell Growth Inhibition (2018) (6)
- Safety and tolerability of empagliflozin and linagliptin combination therapy in patients with type 2 diabetes mellitus: a pooled analysis of data from five randomized, controlled clinical trials (2020) (6)
- Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study (2021) (6)
- Steno-Stiffness Approach for Cardiovascular Disease Risk Assessment in Primary Prevention (2019) (6)
- Long-term safety and efficacy of alogliptin, a DPP-4 inhibitor, in patients with type 2 diabetes: a 3-year prospective, controlled, observational study (J-BRAND Registry) (2021) (5)
- Efficacy of acarbose in different geographical regions of the world: analysis of a real-life database (2014) (5)
- Minireview: Autophagy in Pancreatic (cid:2) -Cells and Its Implication in Diabetes (2015) (5)
- Development of monoclonal mouse antibodies that specifically recognize pancreatic polypeptide. (2019) (5)
- Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry (2018) (5)
- Left atrial dysfunction and stiffness in pediatric and adult patients with Type 1 diabetes mellitus assessed with speckle tracking echocardiography (2020) (5)
- Characteristics of Patients With Graves Disease and Intrathyroid Hypovascularity Compared to Painless Thyroiditis (2014) (5)
- The Effect of Linagliptin versus Metformin Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus (2018) (5)
- Medical nutrition therapy and dietary counseling for patients with diabetes-energy, carbohydrates, protein intake and dietary counseling (2020) (5)
- Establishment of a system for screening autophagic flux regulators using a modified fluorescent reporter and CRISPR/Cas9. (2019) (5)
- Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1. (1994) (5)
- Prevalence and progression of chronic kidney disease among patients with type 2 diabetes: Insights from the DISCOVER study (2020) (5)
- Lack of evident atherosclerosis despite multiple risk factors in glycogen storage disease type 1a with hyperadiponectinemia. (2007) (5)
- Angiotensin II receptor blocker provides pancreatic beta-cell protection independent of blood pressure lowering in diabetic db/db mice. (2007) (5)
- Breakfast skipping is associated with persistently increased arterial stiffness in patients with type 2 diabetes (2020) (5)
- Type 2 diabetes and heart failure: insights from the global DISCOVER study (2021) (5)
- Baseline Characteristics of Patients with Type 2 Diabetes Initiating Second-Line Treatment in Japan: Findings from the J-DISCOVER Study (2020) (5)
- Sarcopenic obesity is associated with cognitive impairment in community-dwelling older adults: The Bunkyo Health Study. (2022) (5)
- Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. (2009) (5)
- Evaluation of the Effect of Alogliptin on Tissue Characteristics of the Carotid Wall: Subanalysis of the SPEAD-A Trial (2018) (5)
- Comparison of thrice‐daily lispro 50/50 vs thrice‐daily lispro in combination with sulfonylurea as initial insulin therapy for type 2 diabetes (2010) (5)
- Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of the AYAME study (2022) (4)
- Efficacy and safety of oral semaglutide in Japanese patients with type 2 diabetes: A post hoc subgroup analysis of the PIONEER 1, 3, 4 and 8 trials (2021) (4)
- Protocol for a large-scale prospective observational study with alogliptin in patients with type 2 diabetes: J-BRAND Registry (2014) (4)
- ALDH2 rs671 is associated with elevated FPG, reduced glucose clearance and hepatic insulin resistance in Japanese men. (2021) (4)
- Associations between second‐line glucose‐lowering combination therapies with metformin and HbA1c, body weight, quality of life, hypoglycaemic events and glucose‐lowering treatment intensification: The DISCOVER study (2021) (4)
- Efficacy and safety of the fixed‐ratio combination of insulin degludec and liraglutide by baseline glycated hemoglobin, body mass index and age in Japanese individuals with type 2 diabetes: A subgroup analysis of two phase III trials (2021) (4)
- Efficacy and Safety of Vildagliptin as an Add-On Therapy in Inadequately Controlled Type 2 Diabetes Patients Treated With Basal Insulin (2017) (4)
- Three days of a eucaloric, low-carbohydrate/high-fat diet increases insulin clearance in healthy non-obese Japanese men (2019) (4)
- The Influence of Sitagliptin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Prespecified Sub-Analysis (2017) (4)
- Clinical factors associated with bacterial translocation in Japanese patients with type 2 diabetes: A retrospective study (2019) (4)
- What are the factors associated with long‐term glycaemic control in patients with type 2 diabetes and elevated glycated haemoglobin (≥7.0%) at initiation of second‐line therapy? Results from the DISCOVER study (2021) (4)
- Combined genotypes of ACE and NADPH oxidase p22phox associated with somatic mutation of mtDNA and carotid intima-media thickness in Japanese patients with type 2 diabetes mellitus☆ (2002) (4)
- Association of T2 relaxation time determined by magnetic resonance imaging and intramyocellular lipid content of the soleus muscle in healthy subjects (2011) (4)
- Current understanding of the effect of sodium–glucose co-transporter-2 inhibitors in Asian patients with diabetes mellitus (2020) (4)
- Impact of diet on the efficacy of insulin lispro 25/75 and insulin lispro 50/50 as starter insulin in East Asian patients with type 2 diabetes: subgroup analysis of the CLASSIFY randomized trial. (2016) (4)
- Benefits of the fixed‐ratio combination of insulin glargine 100 units/mL and lixisenatide (iGlarLixi) in Japanese people with type 2 diabetes: A subgroup and time‐to‐control analysis of the LixiLan JP phase 3 trials (2020) (4)
- Spatial and transcriptional heterogeneity of pancreatic beta cell neogenesis revealed by a time-resolved reporter system (2022) (4)
- Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice (2021) (4)
- Abstract TP416: Effects Of Pioglitazone In Patients With Abnormal Glucose Metabolism After Stroke The J-SPIRIT Study (2013) (4)
- Conversion of pancreatic α cells into insulin-producing cells modulated by β-cell insufficiency and supplemental insulin administration. (2019) (4)
- Effects of linagliptin vs. voglibose on daily glucose excursions during continuous glucose monitoring of Japanese type 2 diabetes patients (L-CGM): A randomized, open-label, two-arm, parallel comparative trial. (2017) (3)
- Efficacy and adverse effects of low-dose nateglinide in early type 2 diabetes: comparison with acarbose in a crossover study (2010) (3)
- Leukotriene A4 hydrolase deficiency protects mice from diet‐induced obesity by increasing energy expenditure through neuroendocrine axis (2020) (3)
- Erratum. Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). Diabetes Care 2016;39:139–148 (2017) (3)
- Analysis of clinical factors contributing to the postglucagon increment in C-peptide levels in Japanese patients with type 2 diabetes: comparison with basal C-peptide levels and 24-h urinary C-peptide excretion (2013) (3)
- Maintenance of contractile force and increased fatigue resistance in slow-twitch skeletal muscle of mice fed a high-fat diet. (2020) (3)
- Olmesartan and telmisartan comparably preserve pancreatic beta-cell mass with reduction of oxidative stress in db/db mice (2014) (3)
- White matter fiber-specific degeneration in older adults with metabolic syndrome (2022) (3)
- Evidence‐based comparison of glucagon‐like peptide receptor agonists and sodium–glucose cotransporter 2 inhibitors (2019) (3)
- Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice (2018) (3)
- Study Protocol for the Initial Choice of DPP-4 Inhibitor in Japanese Patients with Type 2 diabetes Mellitus: Effect of Linagliptin on QOL (INTEL-QOL) Trial (2018) (3)
- Effects of SGLT2 Inhibitors on Insulin Secretion and Insulin Resistance—Results from a Cross-Sectional Study (2018) (3)
- Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study (2022) (3)
- Real-World Data on the Incidence of Macrovascular Complications in Japanese Patients with Type 2 Diabetes: The Sitagliptin Registration Type 2 Diabetes-Juntendo Collaborating Project (2019) (3)
- Metformin discontinuation in patients beginning second-line glucose-lowering therapy: results from the global observational DISCOVER study programme (2020) (3)
- PKC-DELTA PLAYS NON-REDUNDANT ROLE IN INSULIN SECRETION IN PANCREATIC BETA CELL * (2006) (3)
- Beneficial effects of vildagliptin combined with miglitol on glucose tolerance and islet morphology in diet-controlled db/db mice. (2013) (3)
- Cellular Autophagy in α Cells Plays a Role in the Maintenance of Islet Architecture (2019) (3)
- Interconnection between cardiovascular, renal and metabolic disorders: A narrative review with a focus on Japan (2022) (3)
- Retraction. Angiotensin II receptor blocker provides pancreatic beta-cell protection independent of blood pressure lowering in diabetic db/db mice. (2007) (2)
- The Importance of Continuous Glucose Monitoring-derived Metrics Beyond HbA1c for Optimal Individualized Glycemic Control (2022) (2)
- Measuring Effectiveness of Glimepiride Titration Using SMBG in Patients with Mild Type 2 Diabetes (2009) (2)
- Comparison of effects of azelnidipine and trichlormethiazide in combination with olmesartan on blood pressure and metabolic parameters in hypertensive type 2 diabetic patients (2011) (2)
- 420-P: Micro- and Macrovascular Events in Patients with T2D—Results from the Global DISCOVER Study (2019) (2)
- Fasting serum free glycerol concentration is a potential surrogate marker of visceral obesity and insulin sensitivity in middle-aged Japanese men. (2020) (2)
- New role for alpha cells as a source for new beta cells (2010) (2)
- A case of false hypoglycemia by SMBG due to improper storage of glucometer test strips (2014) (2)
- 148-OR: IDegLira Improves Glycemic Control in Japanese Patients with Type 2 Diabetes (T2D) Uncontrolled on Premixed Insulin Therapy (2019) (2)
- Short-term physical inactivity induces diacylglycerol accumulation and insulin resistance in muscle via lipin1 activation. (2021) (2)
- Glycaemic, lipid and blood pressure control according to guidelines in patients initiating second-line glucose-lowering therapy: results from the global DISCOVER study (2017) (2)
- Effect of real‐life insulin pump with predictive low‐glucose management use for 3 months: Analysis of the patients treated in a Japanese center (2020) (2)
- Reduced muscle strength of knee extensors is a risk factor for silent lacunar infarcts among Japanese elderly people: the Bunkyo Health Study (2020) (2)
- Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study (2022) (2)
- A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium‐glucose co‐transporter‐2 inhibitor tofogliflozin (2020) (2)
- Associations of Exercise Habits in Adolescence and Old Age with Risk of Osteoporosis in Older Adults: The Bunkyo Health Study (2021) (2)
- Neuroimaging findings related to glymphatic system alterations in older adults with metabolic syndrome (2023) (2)
- Clinical Significance of Insulin Sensitivity in Adipose Tissue in Apparently Healthy Nonobese Men (2018) (2)
- Socioeconomic factors associated with hypoglycaemia in patients starting second-line glucose-lowering therapy: the DISCOVER study. (2020) (2)
- Response to Comment on Mita et al. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial. Diabetes Care 2016;39:455–464 (2016) (2)
- Alterations in the mitral flow velocity pattern induced by acute myocardial infarction. Doppler findings before and after infarction. (1995) (2)
- Health-related quality of life in patients with type 2 diabetes initiating a second-line glucose-lowering therapy: the DISCOVER study. (2021) (2)
- Safety and efficacy of metformin up-titration in Japanese patients with type 2 diabetes mellitus treated with vildagliptin and low-dose metformin (2017) (2)
- Switching to once-weekly insulin icodec versus once-daily insulin degludec in individuals with basal insulin-treated type 2 diabetes (ONWARDS 2): a phase 3a, randomised, open label, multicentre, treat-to-target trial (2023) (2)
- Rubicon in pancreatic beta cells plays a limited role in maintaining glucose homeostasis following increased insulin resistance. (2020) (2)
- Effect of thyroxine treatment on pregnancy outcomes in infertile Japanese women with TSH levels between 2.5 μIU/mL and the upper reference limit: a retrospective study. (2020) (2)
- 1864-P: Higher Relative Abundance of Bacteroidetes in Gut Microbiota Is Associated with Decreased Insulin Clearance and Insulin Sensitivity after a Short-Term High-Calorie, High-Fat Diet in Healthy Men (2020) (2)
- Endurance Runners with Intramyocellular Lipid Accumulation and High Insulin Sensitivity Have Enhanced Expression of Genes Related to Lipid Metabolism in Muscle (2020) (2)
- Clinical evidence regarding factors linking metabolic abnormal obesity to pancreatic β‐cell dysfunction (2020) (2)
- The PREDICTIVETM Study: a multinational, prospective observational study to evaluate the safety and efficacy of insulin detemir treatment in patients with type 1 and 2 diabetes—data from the Japan cohort (2012) (2)
- Insulin resistance and muscle weakness are synergistic risk factors for silent lacunar infarcts: the Bunkyo Health Study (2021) (2)
- Association between the lower serum PIICP level and the joint space narrowing on the asymptomatic knee OSTEOARTHRITIS IN MEN IN EARLY FORTIES (2014) (2)
- The Shape of the Glucose Response Curve during an Oral Glucose Tolerance Test Was Associated with Muscle Insulin Sensitivity and Visceral Fat Accumulation in Nonobese Healthy Men (2018) (2)
- Impact of micro‐ and macrovascular complications of type 2 diabetes on quality of life: Insights from the DISCOVER prospective cohort study (2022) (2)
- Long-Term Effect of Febuxostat on Endothelial Function in Patients With Asymptomatic Hyperuricemia: A Sub-Analysis of the PRIZE Study (2022) (2)
- Cost-Effectiveness Analysis of Linagliptin in Japan Based on Results from the Asian Subpopulation in the CARMELINA® Trial (2020) (2)
- Adipose tissue insulin resistance and decreased adiponectin are correlated with metabolic abnormalities in non-obese men. (2021) (2)
- Effects of linagliptin versus voglibose on treatment-related quality of life in patients with type 2 diabetes: sub-analysis of the L-STEP study. (2018) (2)
- Influence of Short-term Dietary and Therapeutic Iodine Restriction on the Therapeutic Effects of Radioactive Iodine Therapy in Patients with Graves' Disease. (2020) (2)
- Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross‐over randomized trial (2020) (1)
- RELATIONSHIP BETWEEN THE EFFECTIVENESS OF INORGANIC IODINE AND THE SEVERITY OF GRAVES THYROTOXICOSIS: A RETROSPECTIVE STUDY. (2017) (1)
- [Disorder of vascular smooth muscle cell and platelet function in diabetes]. (2010) (1)
- 1704-P: Coexistence of Hypoadiponectinemia and Impaired Adipose Tissue Insulin Sensitivity Increases the Risk of Metabolic Abnormality Due to Muscle Insulin Resistance in Nonobese Japanese Men (2020) (1)
- PDB16 - COMPARE RENAL FUNCTIONAL PRSERVATION OUTCOME OF SGLT2 INHIBITOR VS DPP4 INHIBITOR IN PATIENTS WITH TYPE 2 DIABETES: A RETROSPECTIVE COHORT STUDY OF JAPANESE COMMERCIAL DATABASE WITH ADVANCED ANALYTICS APPROACH (2018) (1)
- [Sodium glucose cotransporter inhibitors]. (2012) (1)
- A Pilot Study of Intervention With a Mobile Application Visualizing the Macronutrient Content for Type 2 Diabetes at a Japanese Center (2021) (1)
- Associations between continuous glucose monitoring-derived metrics and HbA1c in patients with type 2 diabetes mellitus. (2022) (1)
- Etiology of Insulin Resistance in Asian Non-Obese Subjects -Juntendo Sportology Center Core Study- (2016) (1)
- Characteristics associated with elevated 1‐h plasma glucose levels during a 75‐g oral glucose tolerance test in non‐obese Japanese men (2020) (1)
- SAT-139 Clinical Impact of Oral Semaglutide Compared with Sitagliptin in T2D on Metformin ± Sulfonylurea: The Pioneer 3 Trial (2019) (1)
- Identification of Risk Factors for Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes Mellitus (2022) (1)
- Monocyte and Basophil Counts as Predictors of Neutrophil Count Recovery in Patients with Thiamazole-Induced Agranulocytosis. (2016) (1)
- Quality of life in people with type 2 diabetes in the 3years following initiation of second-line therapy: The DISCOVER study. (2022) (1)
- The lower cartilage synthesis, but not higher cartilage destruction, is associated with the knee joint space width in men in early forties without knee pain (2015) (1)
- The Effect of Long-Term Inorganic Iodine on Intrathyroidal Iodothyronine Content and Gene Expression in Mice with Graves' Hyperthyroidism (2022) (1)
- 293-LB: The Suppression of Xanthine Oxidoreductase (XOR) Improves Skeletal Muscle Insulin Resistance (2019) (1)
- Changes in Treatment Satisfaction Over 3 Years in Patients With Type 2 Diabetes After Initiating Second-line Treatment (2022) (1)
- Early versus late intensification of glucose-lowering therapy in patients with type 2 diabetes: results from the DISCOVER study. (2021) (1)
- Association of gut microbiota and inflammatory markers in obese patients with type 2 diabetes mellitus: post hoc analysis of a synbiotic interventional study (2022) (1)
- Febuxostat Improves Insulin Resistance in the Skeletal Muscle In Vitro and In Vivo (2018) (1)
- Cumulative autophagy insufficiency in mice leads to progression of β-cell failure. (2022) (1)
- [Epidemiology of elderly diabetes mellitus in Japan]. (2013) (1)
- [Epidemiology of elderly diabetes mellitus in Japan]. (2013) (1)
- [Role of autophagy in pancreatic beta-cell homeostasis]. (2012) (1)
- Intracellular lipid accumulation and insulin resistance in skeletal muscle and liver (2007) (1)
- Three-Year Glycaemic Control and Management in Patients with Type 2 Diabetes Initiating Second-Line Treatment in Japan: A Prospective Observational Study, J-DISCOVER (2021) (1)
- Effects of linagliptin monotherapy compared with voglibose on postprandial lipid profiles in Japanese patients with type 2 diabetes: linagliptin study of effects on postprandial blood glucose (L-STEP) sub-study 1. (2018) (1)
- Inceptor intercepts insulin signaling in pancreatic β‐cells (2021) (1)
- Fulminant emphysematous pyelonephritis (EPN) in a diabetic patient suspected of having multiple tumors. (2010) (1)
- Risk factor analysis for type 2 diabetic patients about hypoglycemia using continuous glucose monitoring: Results from a prospective observational study. (2022) (1)
- Manganese Superoxide Dismutase Polymorphism (V16A) Associated with Impaired Cardiac Autonomic Function in Japanese Type 2 Diabetic Patients (2007) (1)
- Medial meniscus extrusion was associated with the clinical manifestation of the elderlies aged 70's without knee pain with Kellgren-Lawrence grade 2 of knee osteoarthritis (2017) (1)
- Author response for "Superior HbA1c control with the fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with ≤50 units insulin degludec in Japanese subjects with type 2 diabetes in a phase 3, double‐blind, randomised trial" (2019) (1)
- Relationship between blood glucose variability in ambulatory glucose profile and standardized continuous glucose monitoring metrics: Subanalysis of a prospective cohort study (2021) (1)
- Insulin lispro 25/75 and insulin lispro 50/50 as starter insulin in Japanese patients with type 2 diabetes: subanalysis of the CLASSIFY randomized trial. (2017) (1)
- Short-Term SGLT2 Inhibitor Administration Does Not Alter Systemic Insulin Clearance in Type 2 Diabetes (2021) (1)
- Unappreciated role of low‐density lipoprotein receptor‐related protein 1 in pancreatic β cells: Multiple roles of low‐density lipoprotein receptor‐related protein 1 in glucose and lipid metabolism (2018) (1)
- Establishment of an enzyme-linked immunosorbent assay for mouse pancreatic polypeptide clarifies the regulatory mechanism of its secretion from pancreatic γ cells (2022) (1)
- The Multi-Domain Intervention Trial in Older Adults With Diabetes Mellitus for Prevention of Dementia in Japan: Study Protocol for a Multi-Center, Randomized, 18-Month Controlled Trial (2021) (1)
- Lower intake of saturated fatty acids is associated with persistently higher arterial stiffness in patients with type 2 diabetes (2020) (1)
- Replication study of the association of rs7578597 in THADA, rs10886471 in GRK5, and rs7403531 in RASGRP1 with susceptibility to type 2 diabetes among a Japanese population (2015) (1)
- GH-induced LH hyporesponsiveness as a potential mechanism for hypogonadism in male patients with acromegaly. (2021) (1)
- Effect of Plasma Exchange in Thyroid Storm With Consideration of Its Distribution Into the Extravascular Space (2020) (1)
- 1279-P: Socioeconomic Factors Associated with Poor Glycemic Control in People with Type 2 Diabetes: The DISCOVER Study (2019) (1)
- Maintenance of contractile force and increased fatigue resistance in slow‐twitch skeletal muscle of long‐term high‐fat‐fed mice (2017) (1)
- Exercise-Induced Transient Increase in IL-6 Stimulates GLUT4 Expression and Enhances Insulin Sensitivity in Mouse Skeletal Muscle (2016) (1)
- Effectiveness of miglitol combined with various types of insulin therapy for reducing the daily glycemic fluctuation on Japanese type 2 diabetic patients: Evaluation with self-monitoring blood glucose (SMBG) (2013) (0)
- Transcriptional Control of the Differentiation of Pancreatic β Cells (2006) (0)
- Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells. (2023) (0)
- Impact on Diabetes Management of the Restrictions of Social Participation to Combat the COVID-19 Pandemic at a Single Facility in Japan: A Retrospective, Observational Study (2021) (0)
- 1598-P: HbA1c <7.0% 6 Months after Initiation of Second-Line Therapy in Patients with Uncontrolled Type 2 Diabetes Is Associated with Good Glycemic Control at 3 Years: The DISCOVER Study (2020) (0)
- Intramyocellular Lipid Accumulation After High-Fat Diet Is Associated with the Gene Expression Involved in Lipid Metabolism in Skeletal Muscle of Non-Obese Men (2016) (0)
- Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis -The Bunkyo Health Study (2023) (0)
- Investigation for a novel cell-linage to generate endocrine cells in islet by use of mouse genetics. (2019) (0)
- Cause of Hyperglycemia in Postmenopausal Underweight Women with Impaired Glucose Tolerance (2018) (0)
- 1590-P: Effects of Second-Line Metformin Combination Therapies on Weight, HbA1c, and Risk of Hypoglycemia over 3 Years: The DISCOVER Study (2020) (0)
- Abstract 261: Global Patterns of Comprehensive Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes Mellitus Insights From the Global DISCOVER Registry (2018) (0)
- Three days of a eucaloric, low-carbohydrate/high-fat diet increases insulin clearance in healthy non-obese Japanese men (2019) (0)
- Erratum: Regulation of the pancreatic pro-endorine neurogeni3 (Diabetes (2001) 50 (928-936)) (2001) (0)
- Retrospective Study on the Effects of Glucose Abnormality on COVID-19 Outcomes in Japan (2022) (0)
- HbA1c trajectories over 3 years in people with type 2 diabetes starting second-line glucose-lowering therapy: The prospective global DISCOVER study. (2023) (0)
- Potential Usefulness of Intrahepatic Lipid Accumulation and Liver Function Tests to Identify Insulin Resistance Phenotype in Non-Obese Type 2 Diabetes (2016) (0)
- Mechanisms Of Insulin Resistance After 24 Hours Physical Inactivity In Murine Soleus Muscle.: 725 Board #121 May 27, 2 (2015) (0)
- Abstract 14142: Association between Myocardial Triglyceride Content and Cardiac Function in Healthy Subjects and Endurance Athletes: Assessed by 1H-Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging (2012) (0)
- The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus (2021) (0)
- Spatial and transcriptional heterogeneity of β-cell neogenesis revealed by a time-resolved reporter system (2020) (0)
- Fatty Liver Is a Better Marker of Muscle Insulin Resistance than Visceral Fat Accumulation in Nonobese Japanese Men (2018) (0)
- [Compensation and distress in pancreatic beta cells]. (2012) (0)
- Relationship between country income, socioeconomic factors and control of cardiovascular disease risk factors in patients with type 2 Diabetes: insights from the global DISCOVER registry (2020) (0)
- CAN CARDIAC RUPTURE(BLOW OUT TYPE)BE PREDICTED WITH 2-D ECHOCARDIOGRAPHY? (1993) (0)
- Correlates of insulin clearance in apparently healthy non-obese Japanese men (2017) (0)
- [Large-scale clinical studies on diabetic complications]. (2016) (0)
- Author Correction: Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men (2021) (0)
- Association between serum insulin levels and heart failure-related parameters in patients with type 2 diabetes and heart failure treated with canagliflozin: a post-hoc analysis of the randomized CANDLE trial (2022) (0)
- Vascular Events in Patients with Type 2 Diabetes in the Year following Initiation of Second-Line Therapy-The DISCOVER Study (2018) (0)
- Pancreatic ß-Cell Mass Is Determined by ß-Cell Size after Parturition in Mice (2018) (0)
- Zinc and Its Role in the Pathogenesis of Type 2 Diabetes (2014) (0)
- 1448-P: Potential Overtreatment of Older Patients with T2D: The Global DISCOVER Study (2019) (0)
- Association Between Time in Range and HbA1c in Japanese Patients With Type 2 Diabetes Mellitus (2021) (0)
- Beta-cell regeneration therapy as a cure for diabetes mellitus (2008) (0)
- 40-OR: Quality of Life in People with Type 2 Diabetes following Initiation of Second-Line Therapy: DISCOVER (2020) (0)
- A 7 day inpatient diabetes education program improves quality of life and glycemic control 12 months after discharge. (2023) (0)
- Cover Image, Volume 23, Issue 5 (2021) (0)
- Comparison of Brain Volume Measurements Made with 0.3- and 3-T MR Imaging (2021) (0)
- Association between medial meniscus extrusion (MME) and region of meniscal tear in middle aged and elderly population cohort -a sportology core study2- (2019) (0)
- [Autophagy in pancreatic β cells]. (2012) (0)
- [EDIC(1) study]. (2010) (0)
- Associations Between Continuous Glucose Monitoring-derived Metrics and Arterial Stiffness in Patients with Type 2 Diabetes (2020) (0)
- Decreased Muscle Strength of Knee Flexors is Associated with Impaired Muscle Insulin Sensitivity in Non-Diabetic Middle-Aged Japanese Male Subjects (2020) (0)
- [Transcription factors for the insulin gene]. (1994) (0)
- Efficacy and Safety of 1:1 Fixed Ratio Combination of Insulin Glargine/Lixisenatide (iGlarLixi) versus Lixisenatide in Japanese Patients with Type 2 Diabetes Mellitus Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial (2020) (0)
- [NEMOes, a new method to evaluate early atherosclerosis in rodent model]. (2006) (0)
- [Protective effects of incretin on atherosclerosis]. (2011) (0)
- Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men (2020) (0)
- Significance of Feedback Inhibition of Insulin Secretion by Insulin in Healthy Non-obese Men (2018) (0)
- Impact on Diabetes Management Due to Social Participation Restrictions Associated with the COVID-19 Pandemic (2021) (0)
- 2316-PUB: The Effectiveness of Sensor-Augmented Pump Therapy with Automatic Low-Glucose Suspend in Japanese Patients with Type 1 Diabetes (2019) (0)
- Comparison verification between texture analysis based on T2map MRI and histological analysis of the meniscal degeneration in patients with knee osteoarthritis (2018) (0)
- Cover Image, Volume 24, Issue 12 (2022) (0)
- The Impact of Insulin Resistance in Vascular Cells on Atherosclerosis (2010) (0)
- Drug-Eluting Stents for Diabetic Patients With De Novo Coronary Lesion'' Letter by Watada et al Regarding Article, ''Two-Year Clinical Outcomes With (2013) (0)
- [The measurement of intima-media thickness using carotid ultrasonography]. (2011) (0)
- Effects of exercise habits in adolescence and older age on sarcopenia risk in older adults: the Bunkyo Health Study. (2023) (0)
- Novel Spatiotemporal Analysis for Exploring a-Cell Differentiation (2018) (0)
- Erratum. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE). A Randomized Controlled Trial. Diabetes Care 2016;39:455–464 (2017) (0)
- P192Associations between ectopic fat accumulations and cardio-metabolic factors in apparently healthy subjects: assessed by 1H-magnetic resonance spectroscopy in myocardium, liver, and skeletal muscles (2019) (0)
- P1358 New insights into cardiac dysfunction assessed by left atrial function in patients with type 1 diabetes mellitus (2020) (0)
- Letter by Watada et al regarding article, "Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesion". (2008) (0)
- Investigation of clinical factors associated with development of chronic kidney disease and eGFR decline in Japanese patients with type 2 diabetes mellitus (2010) (0)
- 2162-P: Autophagy Deficiency Cumulatively Causes ß-Cell Failure in Mice (2019) (0)
- 6. The Relationship between Olfactory Dysfunction and Cognitive Impairment in Elderly Patients with Type 2 Diabetes Mellitus (1323-P) (2014) (0)
- 1116-P: Effect of Tofogliflozin on Carotid Intima-Media Thickness in Patients with Type 2 Diabetes: Results from the Prospective, Randomized, Open-Label, Parallel-Group Comparative UTOPIA Trial (2020) (0)
- 225-OR: The Impact of Visualizing Macronutrient Content via Food-Log App "Calomeal" on Glycemic Control and QoL in People with Type 2 Diabetes (2020) (0)
- Author response for "Left atrial dysfunction and stiffness in pediatric and adult patients with type 1 diabetes mellitus assessed with speckle tracking echocardiography" (2020) (0)
- Glucose homeostasis in a diabetic patient during liver transplantation: a case report. (2007) (0)
- Three Days Low-carbohydrate/High-fat Diet Increases Insulin Clearance in Non-obese Healthy Men (2018) (0)
- Effects of Arterial Stiffness on Cerebral WM Integrity in Older Adults: A Neurite Orientation Dispersion and Density Imaging and Magnetization Transfer Saturation Imaging Study (2022) (0)
- What We Learned from Brain MR Study from the Sportology Project (2016) (0)
- CLINICAL IMPLICATION OF CONTRAST ECHOCARDIOGRAPHIC "NO REFLOW"PHENOMENON : A PREDICTOR OF LEFT VENTRICULAR DILATION IN PATIENTS WITH REPERFUSED ANTERIOR MYOCARDIAL INFARCTION (1993) (0)
- 2. Recent Progress of Diabetes Care (2020) (0)
- [The impact of strict glycemic control on diabetic microangiopathy]. (2010) (0)
- 2128-P: Exploring the Role of Autophagy in Pancreatic Alpha Cells (2019) (0)
- Treatment patterns and satisfaction in patients with type 2 diabetes newly initiating oral monotherapy with antidiabetic drugs in Japan: results from the prospective Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND) (2022) (0)
- Zinc and iron dynamics in human islet amyloid polypeptide-induced diabetes mouse model (2023) (0)
- Real-World Evidence of Treatment with Teneligliptin/Canagliflozin Combination Tablets for Type 2 Diabetes Mellitus: A Post-Marketing Surveillance in Japan (2022) (0)
- Efficacy of Average Daily Risk Range (ADRR) to Estimate Glycemic Kinetics during Nighttime in Japanese Patients with Type 1 Diabetes Mellitus (2018) (0)
- ASSESSMENT OF MYOCARDIAL VIABILITY IN PATIENTS WITH REPERFUSED ANTERIOR MYOCARDIAL INFARCTION;USEFULNESS OF DOBUTAMINE STRESS ECHOCARDIOGRAPHY IN THE ACUTE STAGE OF INFARCTION (1993) (0)
- 346-LB: The Role of STAT3 Signaling toward a-to-ß Reprogramming within the Adult Pancreas (2019) (0)
- Factors associated with weight loss in people with overweight or obesity living with type 2 diabetes mellitus: Insights from the global DISCOVER study (2022) (0)
- [Effects of angiotensin II type 1 receptor blocker on islet of diabetic db/db mice]. (2007) (0)
- Author Correction: Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men (2020) (0)
- 1135-P: Acute Increase in Endogenous Glucose Production by a Single Administration of Tofogliflozin Is Disappeared by Suppressing Its Glucose Lowering Effect in the Patients with Type 2 Diabetes Mellitus (2020) (0)
- Zinc transporter ZIP13 regulates the adipocyte browning (2015) (0)
- 1941-P: The Relationship among Intramyocellular Lipid, Peak Oxygen Consumption, and Insulin Resistance in Nonobese Japanese Men (2019) (0)
- Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice (2022) (0)
- [ARB as a drug for diabetic microangiopathy]. (2009) (0)
- Pharmacokinetics (PK) and Pharmacodynamics (PD) of Dapagliflozin (DAPA) in Combination with Insulin in Japanese Patients with T1D (2018) (0)
- Defective autophagy in vascular smooth muscle cells enhances the healing of abdominal aortic aneurysm (2021) (0)
- Biphasic changes in β-cell mass around parturition are accompanied by increased serotonin production (2020) (0)
- 1585-P: Reduced Insulin Sensitivity and Muscle Strength Are Independent Risk Factors for Silent Lacunar Infarcts and Synergistically Increase the Risk among Japanese Elderly People: The Bunkyo Health Study (2020) (0)
- [The cutting-edge of medicine; autophagy in pancreatic beta cell--a novel pathogenic factor in diabetes]. (2011) (0)
- Prevention of Worsening Diabetes through Behavioral Changes by an IoT-based Self-Monitoring System in Japan (PRISM-J): Study design and rationale for a multicenter, open-label, randomized parallel-group trial (2021) (0)
- PO192 CHARACTERISTICS OF PATIENTS WITH DIABETES WHO RESPOND BETTER TO ACARBOSE: RESULTS FROM AN ANALYSIS OF A REAL LIFE DATA POOL (2014) (0)
- Effect of Tofogliflozin on Carotid Intima-Media Thickness in Patients with Type 2 Diabetes: Results from the Prospective, Randomized, Open-Label, Parallel-Group Comparative UTOPIA Trial (2020) (0)
- Canagliflozin independently reduced plasma volume from conventional diuretics in patients with type 2 diabetes and chronic heart failure: a subanalysis of the CANDLE trial (2022) (0)
- 1628-P: Changes in HbA1c and Treatment in the Second Year following Initiation of Second-Line Therapy in People with T2D—The Global DISCOVER Study (2019) (0)
- [Genetic factors of diabetes mellitus]. (2010) (0)
- A Claims-Based Cohort Study on the Treatment Patterns of Japanese Patients with Type 2 Diabetes Mellitus and the Association of Early First Physician Visit with Time to Prescription of Oral Hypoglycemic Agents (2021) (0)
- Phase I/IIa Feasibility Trial of Autologous Quality- and Quantity-Cultured Peripheral Blood Mononuclear Cell Therapy for Non-Healing Extremity Ulcers (2022) (0)
- 175-LB: The Impact of Glucose Metabolism Abnormality on the Reduced Muscle Strength Is Higher in Elderly Women than Men: The Bunkyo Health Study (2020) (0)
- Hepatic G0S2 Exacerbates Hepatic Insulin Resistance in Estrogen-Deficient Female Wistar Rats (2018) (0)
- Evaluation of the effect of tofogliflozin on the tissue characteristics of the carotid wall—a sub-analysis of the UTOPIA trial (2022) (0)
- 2185-P: Estimation of Autophagy Flux by a Novel Fluorescent Reporter in Organs Involved in Glucose Metabolism Including Pancreatic ß Cells (2019) (0)
- Role of Exercise Intensity on Intramyocelluar Lipid Level After Exercise in Subjects with Moderate Insulin Resistance (2016) (0)
- The area of abdominal subcutaneous adipose tissue is independently correlated with C-peptide increment during glucagon load in Japanese patients with type 2 diabetes (2013) (0)
- A chronic high-fat diet does not exacerbate muscle atrophy in fast-twitch skeletal muscle of aged mice. (2023) (0)
- [Diabetes mellitus related common medical disorders: recent progress in diagnosis and treatment. Topics: I. Pathophysiology, diagnosis and treatment; 11. Atherosclerosis]. (2013) (0)
- STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1 (2022) (0)
- Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study (2023) (0)
- Acknowledgment to reviewers 2013 (2014) (0)
- Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes (2023) (0)
- Suppression of STAT3 Signaling Promotes Acinar-to-ß Reprogramming Induced by Distinct Transcription Factors (2018) (0)
- 649-P: The 7-Day Diabetes Education Hospitalization Program Improves Quality of Life and Treatment Satisfaction (2020) (0)
- Inhibition of Insulin Secretion Induces Golgi Morphological Changes (2023) (0)
- Insulin Resistance and Muscle Weakness Are Synergistic Risk Factors for Silent Lacunar Infarcts: the Bunkyo Health Study: a Cross Sectional Study (2021) (0)
- Genetic ablation of p62/SQSTM1 demonstrates little effect on pancreatic β-cell function under autophagy deficiency. (2022) (0)
- Texture Analysis Using T2 Image of Medial Meniscus Associated with Meniscal Pathologies (2018) (0)
- [Mechanism of progression of atherosclerosis in patients with impaired glucose tolerance (IGT)]. (2005) (0)
- Association of ALDH2 Genotypes and Alcohol Intake with Dietary Patterns: The Bunkyo Health Study (2022) (0)
- [Targeted therapy for diabetes]. (2012) (0)
- 1143-P: A Single and Chronic SGLT2 Inhibitor Administration Did Not Alter Insulin Clearance in Type 2 Diabetes (2020) (0)
- AUTOPHAGY IN HEALTH AND DISEASE: IV.The role of pancreatic beta-cell (2010) (0)
- Vitamin D levels are inversely associated with osteophyte formation in elderly women, but not men - a population-based cohort study “The Bunkyo Health Study” (2020) (0)
- New factors secreted from islets expand β‐cell mass (2013) (0)
- Treatment patterns and glycated haemoglobin levels over 36 months in individuals with type 2 diabetes initiating second‐line glucose‐lowering therapy: The global DISCOVER study (2022) (0)
- Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study (2017) (0)
- Association between MRI-detected osteophyte formation and bone mineral density in elderlies- a cross-sectional analysis using a population-based cohort study “the bunkyo health study” (2021) (0)
- Author response for "Relationship between blood glucose variability in ambulatory glucose profile and standardized continuous glucose monitoring metrics; sub‐analysis of prospective cohort study" (2021) (0)
- 207-LB: Type 2 Diabetes and Heart Failure: Insights from the DISCOVER Study (2019) (0)
- 1666-P: Metabolic Characteristic of Elevated One-Hour Plasma Glucose Levels during a 75g Oral Glucose Tolerance Test in the Nonobese Japanese Men (2019) (0)
- The lower ratio of the cartilage destruction and synthesis biomarkers is a risk for the radiographic medial knee joint space narrowing in men in early forties without knee osteoarthritis – A three years prospective observational study “sportology core study 1” (2017) (0)
- Association of country economy and socioeconomic factors on risk factor control for primary prevention of cardiovascular disease in patients with diabetes mellitus: Insights from the DISCOVER study (2022) (0)
- Association Between Medial Meniscus Extrusion (MME) and Clinical Manifestations of the Elderlies Who Show Primary Stage Knee Osteoarthritis (OA) with No Need for Treatment - A Populationbased Cohort Study “Sportology Core Study 2” (2018) (0)
- Areal Parcellation and Nucleus-Level Analysis of Human Hypothalamus Using High-Resolution fMRI (2018) (0)
- The Effect of Heart Rate Response to Nocturnal Intermittent Hypoxia in Obstructive Sleep Apne (2011) (0)
- The role of leukotriene A4 hydrolase in metabolism (2017) (0)
- PM Association Between Silent Lacunar Infarcts And Muscle Strength: The Bunkyo Health Study (2020) (0)
- 1861-P: Short-Term Overfeeding with Dairy Fat Impairs Insulin Sensitivity in Muscle and Liver but Increases Adipose Tissue Insulin Sensitivity and Suppresses Postprandial Glucose Rise in Healthy Nonobese Men (2020) (0)
- THE DETERMINANTS OF CONTRAST ECHOCARDIOGRAPHIC "NO REFLOW" PHENOMENON IN PATIENTS WITH REPERFUSED ANTERIOR MYOCARDIAL INFARCTION (1993) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Hirotaka Watada?
Hirotaka Watada is affiliated with the following schools:
