Hiroyuki Arai
#205,495
Most Influential Person Across History
Hiroyuki Arai's AcademicInfluence.com Rankings
Download Badge
Philosophy Biology
Hiroyuki Arai's Degrees
- PhD Neuroscience University of Tokyo
- Doctorate Medicine University of Tokyo
Why Is Hiroyuki Arai Influential?
(Suggest an Edit or Addition)Hiroyuki Arai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment (2004) (4172)
- Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' (1998) (548)
- Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1. (2006) (400)
- The Alzheimer’s Association external quality control program for cerebrospinal fluid biomarkers (2011) (385)
- Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? (2003) (359)
- A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients. (2005) (303)
- Tau in cerebrospinal fluid: A potential diagnostic marker in Alzheimer's disease (1995) (300)
- Novel 18F-Labeled Arylquinoline Derivatives for Noninvasive Imaging of Tau Pathology in Alzheimer Disease (2013) (270)
- 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease (2016) (269)
- Interventions to Prevent Pneumonia Among Older Adults (2001) (259)
- Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231. (2002) (257)
- CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects (2002) (241)
- Effects of brain-penetrating ACE inhibitors on Alzheimer disease progression (2004) (239)
- Large‐scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease (2001) (224)
- 2-(2-[2-Dimethylaminothiazol-5-yl]Ethenyl)-6- (2-[Fluoro]Ethoxy)Benzoxazole: A Novel PET Agent for In Vivo Detection of Dense Amyloid Plaques in Alzheimer's Disease Patients (2007) (223)
- Clinical Diagnosis (1890) (220)
- Impaired efficacy of cough in patients with Parkinson disease. (2003) (214)
- High incidence of pneumonia in elderly patients with basal ganglia infarction. (1997) (211)
- Glucose Hypometabolism and Neuropathological Correlates in Brains of Dementia with Lewy Bodies (2000) (207)
- Quinoline and Benzimidazole Derivatives: Candidate Probes for In Vivo Imaging of Tau Pathology in Alzheimer's Disease (2005) (196)
- MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease. (2014) (189)
- Phosphorylated tau in human cerebrospinal fluid is a diagnostic marker for Alzheimer's disease (1999) (180)
- Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease (1997) (177)
- Relation between incidence of pneumonia and protective reflexes in post‐stroke patients with oral or tube feeding (2000) (176)
- Elevated Plasma Homocysteine Levels and Risk of Silent Brain Infarction in Elderly People (2001) (163)
- SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians (2013) (161)
- Risk Factors of Aspiration Pneumonia in Alzheimer’s Disease Patients (2001) (157)
- Cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology. (1997) (156)
- Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. (1990) (146)
- Tau PET Imaging in Alzheimer’s Disease (2014) (146)
- Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. (1998) (144)
- Sleep Patterns and Mortality among Elderly Patients in a Geriatric Hospital (2000) (138)
- A Randomized Trial of Olfactory Stimulation Using Black Pepper Oil in Older People with Swallowing Dysfunction (2006) (138)
- Adiponectin in plasma and cerebrospinal fluid in MCI and Alzheimer’s disease (2011) (134)
- The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein (2011) (134)
- CSF Phosphorylated Tau Protein and Mild Cognitive Impairment: A Prospective Study (2000) (129)
- Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese. (2009) (127)
- Risk of falls in Alzheimer's disease: a prospective study. (2005) (124)
- Angiotensin‐Converting Enzyme Inhibitors and Incidence of Alzheimer's Disease in Japan (2004) (123)
- Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease (2017) (122)
- Expression patterns of β‐amyloid precursor protein (β‐APP) in neural and nonneural human tissues from alzheimer's disease and control subjects (1991) (119)
- Amantadine and pneumonia (1999) (115)
- 18F-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies (2000) (114)
- Docosahexaenoic acid: one molecule diverse functions (2017) (113)
- Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease. (2002) (110)
- Factors associated with suicidal ideation in an elderly urban Japanese population: A community‐based, cross‐sectional study (2005) (108)
- Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β‐amyloid proteins (2006) (107)
- Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer’s disease pathology (2012) (106)
- Male elderly subthreshold depression patients have smaller volume of medial part of prefrontal cortex and precentral gyrus compared with age-matched normal subjects: a voxel-based morphometry. (2005) (106)
- Oral hygiene reduces respiratory infections in elderly bed-bound nursing home patients. (1996) (104)
- Cerebrospinal Fluid Amyloid β1–42 Levels in the Mild Cognitive Impairment Stage of Alzheimer's Disease (2001) (103)
- [18F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer’s disease (2015) (101)
- Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine. (2001) (101)
- In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET (2016) (100)
- In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy. (2010) (98)
- Styrylbenzoxazole Derivatives for In Vivo Imaging of Amyloid Plaques in the Brain (2004) (97)
- Green tea consumption is associated with depressive symptoms in the elderly. (2009) (96)
- Brain-derived neurotrophic factor gene polymorphisms and Alzheimer’s disease (2005) (96)
- Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease (2005) (93)
- Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer’s disease (2000) (90)
- Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231. (2003) (86)
- Characteristics of Tau and Its Ligands in PET Imaging (2016) (84)
- Levodopa and swallowing reflex (1996) (84)
- Silent cerebral infarction: a potential risk for pneumonia in the elderly (2000) (83)
- A Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of the Chinese Herbal Medicine “Ba Wei Di Huang Wan” in the Treatment of Dementia (2004) (80)
- Diagnostic significance of tau protein in cerebrospinal fluid from patients with corticobasal degeneration or progressive supranuclear palsy (2001) (79)
- A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6‐penta‐O‐galloyl‐β‐d‐glucopyranose have potent anti‐aggregation effects on Alzheimer’s amyloid β proteins in vitro and in vivo (2009) (79)
- Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351 (2016) (78)
- Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease. (2006) (76)
- Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis. (2008) (75)
- Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways. (2004) (75)
- Amyloid β Levels in Human Red Blood Cells (2012) (75)
- Tau imaging with [18F]THK‐5351 in progressive supranuclear palsy (2017) (74)
- Docosahexaenoic acid disrupts in vitro amyloid β1‐40 fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer’s disease model rats (2008) (73)
- Cerebrospinal fluid tau in dementia disorders: a large scale multicenter study by a Japanese study group (2002) (72)
- Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [18F]THK-5117 Positron Emission Tomography (2015) (71)
- Genetic association study on in and around the APOE in late-onset Alzheimer disease (2009) (71)
- Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials (2018) (71)
- Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation. (2009) (68)
- Recent advances in the development of amyloid imaging agents. (2007) (68)
- Hippocampal Blood Flow Abnormality Associated With Depressive Symptoms and Cognitive Impairment in Patients With Chronic Heart Failure. (2016) (67)
- Widespread expression of α-synuclein and τ immunoreactivity in Hallervorden–Spatz syndrome with protracted clinical course (2000) (66)
- Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade. (2009) (65)
- Effects of the traditional Chinese herbal medicine Yi-Gan San for cholinesterase inhibitor-resistant visual hallucinations and neuropsychiatric symptoms in patients with dementia with Lewy bodies. (2005) (65)
- Macrophage colony-stimulating factor improves cardiac function after ischemic injury by inducing vascular endothelial growth factor production and survival of cardiomyocytes. (2007) (63)
- Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population. (2014) (61)
- Apolipoprotein E gene in Parkinson's disease with or without dementia (1994) (60)
- Increased plasma 8-isoprostane levels in hypertensive subjects: the Tsurugaya Project. (2004) (60)
- A Pilot Study of Banxia Houpu Tang, a Traditional Chinese Medicine, for Reducing Pneumonia Risk in Older Adults with Dementia (2007) (59)
- Apolipoprotein E gene in diffuse Lewy body disease with or without co-existing Alzheimer's disease (1994) (59)
- Genetic association of CTNNA3 with late-onset Alzheimer's disease in females. (2007) (59)
- Cerebrospinal fluid tau protein shows a better discrimination in young old (<70 years) than in old old patients with Alzheimer's disease compared with controls (1999) (59)
- A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH (2012) (59)
- A comparison of tau protein in cerebrospinal fluid between corticobasal degeneration and progressive supranuclear palsy (1999) (58)
- Fall Prevention Using Olfactory Stimulation with Lavender Odor in Elderly Nursing Home Residents: A Randomized Controlled Trial (2012) (57)
- Comparison study of amyloid PET and voxel-based morphometry analysis in mild cognitive impairment and Alzheimer's disease (2009) (56)
- Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia. (2006) (55)
- The neural correlates of driving performance identified using positron emission tomography (2005) (55)
- Antithrombotic Therapy for Prevention of Pneumonia (2001) (55)
- [18F]FDG-PET study in dementia with lewy bodies and alzheimer's disease (2001) (54)
- No increase in cerebrospinal fluid tau protein levels in patients with vascular dementia (1998) (54)
- The frequency of the methylenetetrahydrofolate reductase-gene mutation varies with age in the normal population. (1997) (54)
- New strategies for aspiration pneumonia. (1997) (53)
- High Expression of Apolipoprotein E mRNA in the Brains with Sporadic Alzheimer’s Disease (2001) (53)
- Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease (2012) (52)
- Basic and clinical studies on the measurement of tau protein in cerebrospinal fluid as a biological marker for Alzheimer's disease and related disorders: multicenter study in Japan. (1998) (52)
- Polymorphisms of dopamine receptor and transporter genes and Parkinson's disease (1995) (49)
- Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease. (2012) (49)
- Differential subcellular localization of neural isoforms of the catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin) in central nervous system neurons: immunohistochemistry on formalin-fixed paraffin sections employing antigen retrieval by microwave irradiation. (1996) (49)
- A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: a population-based, cross-sectional analysis. (2013) (49)
- Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals (1997) (48)
- Advances in the development of tau PET radiotracers and their clinical applications (2016) (47)
- Cerebrospinal fluid tau protein levels in demented and nondemented alcoholics. (1999) (46)
- Nobiletin‐rich Citrus reticulata peels, a kampo medicine for Alzheimer's disease: A case series (2013) (45)
- Differential cognitive effects of ebastine and (+)-chlorpheniramine in healthy subjects: correlation between cognitive impairment and plasma drug concentration. (2002) (45)
- Significance of lutein in red blood cells of Alzheimer's disease patients. (2012) (45)
- Lewy bodies contain beta-amyloid precursor proteins of Alzheimer's disease (1992) (45)
- Epitope analysis of senile plaque components in the hippocampus of patients with Parkinson's disease (1992) (45)
- ACE activity in CSF of patients with mild cognitive impairment and Alzheimer disease (2006) (45)
- Impaired urge-to-cough in elderly patients with aspiration pneumonia (2008) (44)
- Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy (2018) (44)
- Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain. (1996) (44)
- Effect of kami-untan-to on the impairment of learning and memory induced by thiamine-deficient feeding in mice (2004) (43)
- Histamine H(1) receptors in patients with Alzheimer's disease assessed by positron emission tomography. (2000) (43)
- The effects of the traditional chinese medicine, "Banxia Houpo Tang (Hange-Koboku To)" on the swallowing reflex in Parkinson's disease. (2000) (43)
- The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community. (2005) (42)
- Soluble Amyloid Precursor Protein 770 Is Released from Inflamed Endothelial Cells and Activated Platelets (2012) (42)
- Alterations in the Levels of Amyloid-β, Phospholipid Hydroperoxide, and Plasmalogen in the Blood of Patients with Alzheimer's Disease: Possible Interactions between Amyloid-β and These Lipids. (2015) (41)
- In vivo detection of amyloid plaques in the mouse brain using the near-infrared fluorescence probe THK-265. (2011) (41)
- Antioxidant effect of lutein towards phospholipid hydroperoxidation in human erythrocytes. (2009) (41)
- Apolipoprotein E genotyping and cerebrospinal fluid tau protein: implications for the clinical diagnosis of Alzheimer's disease. (1997) (41)
- YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology (2020) (41)
- Impact of physical activity and performance on medical care costs among the Japanese elderly (2011) (41)
- Development of a high-performance liquid chromatography-based assay for carotenoids in human red blood cells: application to clinical studies. (2008) (41)
- Amyloid PET in mild cognitive impairment and Alzheimer’s disease with BF-227: comparison to FDG–PET (2010) (41)
- A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid β proteins in vitro and in vivo (2009) (40)
- Dementia caregivers’ burdens and use of public services (2005) (40)
- Herpes simplex virus and risk of Alzheimer's disease (1997) (40)
- Neuroanatomical correlates of low body weight in Alzheimer's disease: a PET study (2002) (40)
- Presenilin-1 polymorphism and Alzheimer's disease (1996) (39)
- Expression patterns of beta-amyloid precursor protein (beta-APP) in neural and nonneural human tissues from Alzheimer's disease and control subjects. (1991) (38)
- Relationship between trait anxiety, brain activity and natural killer cell activity in cancer patients: a preliminary PET study (2001) (38)
- Use of a Benzimidazole Derivative BF-188 in Fluorescence Multispectral Imaging for Selective Visualization of Tau Protein Fibrils in the Alzheimer’s Disease Brain (2014) (38)
- Dietary patterns associated with fall-related fracture in elderly Japanese: a population based prospective study (2010) (38)
- Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter (2008) (38)
- A novel imaging probe for in vivo detection of neuritic and diffuse amyloid plaques in the brain (2007) (37)
- Coffee treatment prevents the progression of sarcopenia in aged mice in vivo and in vitro (2014) (37)
- In vivo detection of prion amyloid plaques using [11C]BF-227 PET (2010) (36)
- Cathepsin D polymorphism not associated with Alzheimer's disease in Japanese (2001) (36)
- Sugar Chains of Cerebrospinal Fluid Transferrin as a New Biological Marker of Alzheimer’s Disease (2008) (35)
- Sitting Position to Prevent Aspiration in Bed-Bound Patients (2002) (35)
- Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging. (2014) (35)
- Cerebrospinal fluid levels of amyloid β-peptide1–42, but not tau have positive correlation with brain glucose metabolism in humans (1999) (35)
- Association between a polymorphism of brain‐derived neurotrophic factor gene and sporadic Parkinson's disease (2003) (34)
- No evidence of linkage or association between tyrosine hydroxylase gene and affective disorder. (1995) (34)
- Regional cerebral glucose utilization is modulated by the dosage of apolipoprotein E type 4 allele and α1‐antichymotrypsin type A allele in Alzheimer's disease (1997) (34)
- BENEFITS OF COMBINING DONEPEZIL PLUS TRADITIONAL JAPANESE HERBAL MEDICINE ON COGNITION AND BRAIN PERFUSION IN ALZHEIMER'S DISEASE: A 12‐WEEK OBSERVER‐BLIND, DONEPEZIL MONOTHERAPY CONTROLLED TRIAL (2006) (33)
- GAB2 is not associated with late-onset Alzheimer's disease in Japanese (2009) (33)
- [Prediction of progression in patients with mild cognitive impairment using IMP-SPECT]. (2000) (33)
- Royal jelly prevents the progression of sarcopenia in aged mice in vivo and in vitro. (2013) (33)
- Accurate quantitation of choline and ethanolamine plasmalogen molecular species in human plasma by liquid chromatography–tandem mass spectrometry (2017) (32)
- Changes of Blood Flow Volume in the Superior Mesenteric Artery and Brachial Artery with Abdominal Thermal Stimulation (2009) (32)
- Exacerbation of dementia after the earthquake and tsunami in Japan (2012) (32)
- The apolipoprotein E gene in Binswanger's disease and vascular dementia (1996) (31)
- Acupuncture for patients with glaucoma. (2005) (31)
- Pupil dilatation assay by tropicamide is modulated by apolipoprotein E e4 allele dosage in Alzheimer's disease (1996) (30)
- Effects of capsiate on the triggering of the swallowing reflex in elderly patients with aspiration pneumonia (2010) (30)
- Shelter‐Acquired Pneumonia After a Catastrophic Earthquake in Japan (2011) (30)
- ACUPUNCTURE FOR DYSPHAGIA IN POSTSTROKE PATIENTS: A VIDEOFLUOROSCOPIC STUDY (2005) (30)
- Amyloid deposits and response to shunt surgery in idiopathic normal-pressure hydrocephalus (2015) (30)
- Aging deteriorated perception of urge-to-cough without changing cough reflex threshold to citric acid in female never-smokers (2011) (29)
- 18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging (2020) (29)
- BRIEF COMMUNICATION Mutation in the α-Synuclein Gene and Sporadic Parkinson's Disease, Alzheimer's Disease, and Dementia with Lewy Bodies (1998) (29)
- INTENSIVE STEPWISE METHOD FOR ORAL INTAKE USING A COMBINATION OF TRANSIENT RECEPTOR POTENTIAL STIMULATION AND OLFACTORY STIMULATION INHIBITS THE INCIDENCE OF PNEUMONIA IN DYSPHAGIC OLDER ADULTS (2010) (29)
- CSF‐Phospho‐tau (181P) as a Promising Marker for Discriminating Alzheimer's Disease from Dementia with Lewy Bodies (2002) (29)
- Localization of Calcineurin in the Mature and Developing Retina (2001) (27)
- Plasma Homocysteine and Risk of Coexisting Silent Brain Infarction in Alzheimer’s Disease (2006) (27)
- Elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of Alzheimer's disease elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of Alzheimer's disease. (1999) (27)
- Apolipoprotein E ε4 allele distribution in alcoholic dementia and in Alzheimer's disease in Japan (1994) (27)
- Brain accumulation of amyloid β protein visualized by positron emission tomography and BF‐227 in Alzheimer's disease patients with or without diabetes mellitus (2013) (26)
- ACUPUNCTURE AND SWALLOWING REFLEX IN POSTSTROKE PATIENTS (2003) (26)
- Effect of Genetic Risk Factors and Disease Progression on the Cerebrospinal Fluid Tau Levels in Alzheimer's Disease (1997) (26)
- Potentiation of brain acetylcholine neurons by Kami-Untan-To (KUT) in aged mice: implications for a possible antidementia drug. (2000) (25)
- Arg(184)his mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa‐responsive dystonia with parkinsonism: A case report (2004) (25)
- A 18F-Labeled BF-227 Derivative as a Potential Radioligand for Imaging Dense Amyloid Plaques by Positron Emission Tomography (2013) (25)
- Biological markers for the clinical diagnosis of Alzheimer's disease. (1996) (24)
- Folate Deficiency and Risk of Pneumonia in Older People (2001) (23)
- Biochemical and Ultrastructural Study of Neurofibrillary Tangles in Amyotrophic Lateral Sclerosis/Parkinsonism‐Dementia Complex in the Kii Peninsula of Japan (2003) (23)
- Nicotine imptoves cognitive disturbance in senescence-accelerated mice (1994) (22)
- Prevention of respiratory infections in the elderly (2002) (22)
- Development of the Dementia Assessment Sheet for Community‐based Integrated Care System 8‐items, a short version of the Dementia Assessment Sheet for Community‐based Integrated Care System 21‐items, for the assessment of cognitive and daily functions (2018) (22)
- NOS3 polymorphism not associated with Alzheimer's disease in Japanese (2000) (21)
- Preventive effect of kami-untan-to on performance in the forced swimming test in thiamine-deficient mice: Relationship to functions of catecholaminergic neurons (2007) (21)
- PERIVENTRICULAR WHITE MATTER LESIONS AND SLEEP ALTERATION IN OLDER PEOPLE (2003) (21)
- Pupillary Response to Tropicamide in Japanese Patients with Alcoholic Dementia, Alzheimer's Disease, and Vascular Dementia (1997) (21)
- Clinical and biomarker investigation of a patient with a novel presenilin-1 mutation (A431V) in the mild cognitive impairment stage of Alzheimer’s Disease (2002) (20)
- Radial artery hemodynamic changes related to acupuncture. (2010) (20)
- Cortical Laminar Binding of PET Amyloid and Tau Tracers in Alzheimer Disease (2015) (20)
- Traditional Chinese medicine on four patients with Huntington's disease (2009) (20)
- Absence of Association of α1-Antichymotrypsin Polymorphisms with Alzheimer's Disease: A Report on Autopsy-Confirmed Cases (1998) (19)
- Cerebrospinal Fluid Tau Protein as a Potential Diagnostic Marker in Alzheimer’s Disease (1998) (19)
- Effects of a sedative antihistamine, D‐chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving (2008) (19)
- Alpha2-macroglobulin gene polymorphisms show racial diversity and are not associated with Alzheimer's disease. (2000) (19)
- Vulnerability of the neuronal cytoskeleton in aging and Alzheimer disease: widespread involvement of all three major filament systems. (1990) (19)
- Elevated cerebrospinal fluid tau protein levels in Wernicke's encephalopathy. (2008) (19)
- Effects of sex, educational background, and chronic kidney disease grading on longitudinal cognitive and functional decline in patients in the Japanese Alzheimer's Disease Neuroimaging Initiative study (2018) (18)
- MOSAPRIDE CITRATE PROLONGS SURVIVAL IN STROKE PATIENTS WITH GASTROSTOMY (2007) (18)
- [A new interventional strategy for Alzheimer's disease by Japanese herbal medicine]. (2000) (18)
- Effect of a comprehensive lifestyle modification program on the bone density of male heavy drinkers. (2010) (18)
- [Association between social support and depression in the elderly Japanese population]. (2004) (18)
- The Expression of Presenilin 1 mRNA in Skin Fibroblasts and Brains from Sporadic Alzheimer’s Disease (2000) (17)
- CSF tau protein: A new prognostic marker for Guillain-Barré syndrome (2006) (17)
- Dental status and mortality in institutionalized elderly people (2006) (17)
- Possible Involvement of Iron-Dependent Lipid Peroxidation in the Delayed Neuronal Death of Rat Brain after a Transient Ischemia (1987) (17)
- Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351 (2016) (17)
- Role of Chronic Sinusitis in Cognitive Functioning in the Elderly (2003) (16)
- Presenilin-1 Polymorphism in Alzheimer's Disease and Vascular Dementia (1997) (16)
- [18F]THK-5351 PET imaging in early-stage semantic variant primary progressive aphasia: a report of two cases and a literature review (2018) (16)
- Olfactory stimuli and enhanced postural stability in older adults. (2009) (16)
- Apolipoprotein E epsilon 4 allele and pupillary response to tropicamide. (1997) (16)
- Aspiration Pneumonia and Insular Hypoperfusion in Patients with Cerebrovascular Disease (2004) (15)
- Cardiac positron-emission tomography images with an amyloid-specific tracer in familial transthyretin-related systemic amyloidosis. (2012) (15)
- Utility of SPM8 plus DARTEL (VSRAD) combined with magnetic resonance spectroscopy as adjunct techniques for screening and predicting dementia due to Alzheimer's disease in clinical practice. (2014) (15)
- Serum C-Reactive Protein Even at Very Low (<1.0 mg/l) Concentration Is Associated with Physical Performance in a Community-Based Elderly Population Aged 70 Years and Over (2008) (15)
- A clinical and neuropathological study of an unusual case of sporadic tauopathy. A variant of corticobasal degeneration? (2002) (15)
- Voxel-Based Analysis of Amyloid Positron Emission Tomography Probe [11C]BF-227 Uptake in Mild Cognitive Impairment and Alzheimer’s Disease (2010) (14)
- Tube feeding in terminal elderly care (2003) (14)
- Relationship between peripheral arterial disease and incident disability among elderly Japanese: the Tsurugaya project. (2010) (14)
- Expression of β-amyloid precursor protein in the developing human spinal cord (1994) (14)
- A new therapy for Alzheimer's disease (2004) (14)
- Lower Serum Calcium as a Potentially Associated Factor for Conversion of Mild Cognitive Impairment to Early Alzheimer's Disease in the Japanese Alzheimer's Disease Neuroimaging Initiative. (2019) (14)
- Differential effects of docoosahexaenoic and arachidonic acid on fatty acid composition and myosin heavy chain-related genes of slow- and fast-twitch skeletal muscle tissues (2016) (14)
- Advances in molecular imaging for the diagnosis of dementia. (2009) (14)
- Mutation in the alpha-synuclein gene and sporadic Parkinson's disease, Alzheimer's disease, and dementia with lewy bodies. (1998) (14)
- Aggravation of Alzheimer's disease symptoms after the earthquake in Japan: A comparative analysis of subcategories (2013) (13)
- Survival period after tube feeding in bedridden older patients (2012) (13)
- Rivastigmine Dermal Patch Solves Eating Problems in an Individual with Advanced Alzheimer's Disease (2012) (13)
- Geriatric medicine, Japanese Alzheimer's disease neuroimaging initiative and biomarker development. (2010) (13)
- ELONGATION OF LIFE EXPECTANCY MAY ACCOMPANY SHIFT OF MEDICAL COST TO OLDER ADULTS (1997) (13)
- Neurochemical regulation of cough response to capsaicin in guinea-pigs. (2002) (12)
- α1-Antichymotrypsin gene polymorphism and risk for Alzheimer's disease (2005) (12)
- Low Serum 1,25-Dihydroxyvitamin D Level and Risk of Respiratory Infections in Institutionalized Older People (2010) (12)
- Acupuncture for Gait Disorders in the Elderly (2004) (11)
- Predicting human performance by channelized Hotelling observer in discriminating between Alzheimer’s dementia and controls using statistically processed brain perfusion SPECT (2006) (11)
- Impact of Blunted Perception of Dyspnea on Medical Care Use and Expenditure, and Mortality in Elderly People (2012) (11)
- No association between DLST gene and Alzheimer’s disease or Wernicke-Korsakoff syndrome (2001) (11)
- Comparison of disabled older people in the USA and Japan (2002) (11)
- Cough reflex and oral chemesthesis induced by capsaicin and capsiate in healthy never-smokers (2007) (11)
- Cognitive function in rats with alcohol ingestion (1995) (11)
- 754 Apolipoprotein E ε4 allele and pupillary response to tropicamide in Alzheimer's disease and cognitively normal subjects (1996) (11)
- Long‐term cognitive benefits of donepezil in Alzheimer’s disease: A retrospective comparison between 1994–1999 and 2000–2004 (2007) (10)
- Effects of air pollution and smoking on chronic obstructive pulmonary disease and bronchial asthma. (1998) (10)
- Nicotine improves cognitive disturbance in senescence-accelerated mice. (1994) (10)
- Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis (2019) (10)
- TEMPORAL PROGRESSION OF HIPPOCAMPAL ATROPHY AND APOLIPOPROTEIN E GENE IN ALZHEIMER'S DISEASE (1996) (10)
- Basic and clinical studies on ApoE gene typing by line probe assay (LiPA) as a biological marker for Alzheimer's disease and related disorders: multicenter study in Japan. (1998) (10)
- Quantitative kinetic analysis of PET amyloid imaging agents [(11)C]BF227 and [(18)F]FACT in human brain. (2015) (10)
- [Alzheimer's disease neuroimaging initiative and mild cognitive impairment]. (2007) (10)
- Longitudinal changes in 18F‐THK5351 positron emission tomography in corticobasal syndrome (2019) (10)
- A modified method of 3D-SSP analysis for amyloid PET imaging using [11C]BF-227 (2011) (9)
- APOE ε4 allele in Alzheimer's and non-Alzheimer's dementias (1996) (9)
- In vivo visualization of a-synuclein deposition by carbon-11-labelled 2-[ 2-( 2-dimethylaminothiazol-5-yl ) ethenyl ]-6-[ 2-( fluoro ) ethoxy ] benzoxazole positron emission tomography in multiple system atrophy (2010) (9)
- Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians (2013) (9)
- Basic and Clinical Studies on the Measurement of β‐amyloid(1–42) in Cerebrospinal Fluid as a Diagnostic Marker for Alzheimer's Disease and Related Disorders: Multi Center Study in Japan (2001) (9)
- Improvement of Swallowing Reflex After Electrical Stimulation to Lower Leg Acupoints in Patients After Stroke (2009) (9)
- Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer's disease. (1996) (8)
- Earthquake in Japan (2011) (8)
- Binding and safety profile of novel benzoxazole derivative for in vivo imaging of amyloid deposits in Alzheimer's disease (2007) (8)
- Evaluation of the biodistribution and radiation dosimetry of the 18F-labelled amyloid imaging probe [18F]FACT in humans (2013) (8)
- Alteration in brain presenilin‐1 mRNA expression in sporadic Alzheimer's disease (1999) (8)
- PET imaging of tau pathology in mild cognitive impairment and Alzheimer's disease with [18F]THK-5351 (2015) (8)
- Reduced brain‐derived neurotrophic factor is associated with cognitive dysfunction in patients with chronic heart failure (2017) (7)
- AMANTADINE AND PNEUMONIA IN ELDERLY STROKE PATIENTS. AUTHORS' REPLY (1999) (7)
- Serum Cholesterol and Cerebrospinal Fluid Amyloid β Protein in Alzheimer'S Disease (2001) (7)
- Introduction and overview of the special issue “Brain imaging and aging”: The new era of neuroimaging in aging research (2016) (7)
- A TRANSIENT INCREASE IN CEREBROSPINAL FLUID TAU LEVEL AFTER EPILEPTIC SEIZURE IN AN ELDERLY PATIENT (2007) (7)
- Adiponectin pathway attenuates malignant mesothelioma cell growth. (2012) (7)
- PARALYTIC ILEUS AFTER DISCONTINUATION OF CHOLINESTERASE INHIBITOR (2006) (7)
- CONTRIBUTION OF GASTRIC ACID IN ELDERLY NURSING HOME PATIENTS WITH COUGH REFLEX HYPERSENSITIVITY (2007) (7)
- 18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies (2021) (7)
- Amantadine and pneumonia in elderly stroke patients (1999) (7)
- Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimer’s Disease (2021) (7)
- No evidence of association between apolipoprotein E gene regulatory region polymorphism and Alzheimer's disease in Japanese (2000) (6)
- Cognitive examination in older adults living in temporary apartments after the Great East Japan Earthquake (2015) (6)
- Subgroup differences in 'brain-type' transferrin and α-synuclein in Parkinson's disease and multiple system atrophy. (2016) (6)
- Current concept and future research directions of mild cognitive impairment (2005) (6)
- C-reactive protein (CRP) is a predictor of high medical-care expenditures in a community-based elderly population aged 70 years and over: the Tsurugaya project. (2012) (6)
- Acid and swallowing reflex (2007) (6)
- Will aging of the population make Japan less productive? (1996) (6)
- SEX DIFFERENCES IN THE PREFERENCE FOR PLACE OF DEATH IN COMMUNITY‐DWELLING ELDERLY PEOPLE IN JAPAN (2008) (6)
- HOMICIDES OF FRAIL OLDER PERSONS BY THEIR CAREGIVERS IN JAPAN (2009) (6)
- Hypoperfusion in the posterior cingulate cortex is associated with lower bone mass density in elderly women with osteopenia and Alzheimer’s disease (2019) (5)
- Dietary intakes and plasma 8-iso-prostaglandin F2alpha concentrations in community-dwelling elderly Japanese: the Tsurugaya project. (2006) (5)
- Apolipoprotein E and Alzheimer’s Disease (1999) (5)
- Expression of beta-amyloid precursor protein in the developing human spinal cord. (1994) (5)
- Apolipoprotein E epsilon 4 allele distribution in alcoholic dementia and in Alzheimer's disease in Japan. (1994) (5)
- Clinical Utility of a Semiquantitative Method Using Lumbar Radiography as a Screening Tool for Osteoporosis in Elderly Subjects (2019) (5)
- Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β (2018) (5)
- Medical costs for older people are not unfairly spent. (1997) (5)
- Congenital tracheal stenosis and an anomalous origin of the right upper lobe bronchus (2008) (5)
- Exhaled carbon monoxide levels in preschool‐age children with episodic asthma (2012) (5)
- [A proposal for diagnostic and clinical assessment criteria for Alzheimer's disease]. (2005) (5)
- In vivo selective imaging of tau pathology in Alzheimer's disease with 18F-THK5117 (2014) (5)
- TERMINAL CARE MEDICAL FEES FOR OLDER ADULTS (1996) (5)
- Disturbed consciousness and asthma (1997) (5)
- Relationship between asthma severity and progression of Alzheimer's disease (2002) (5)
- Cognitive decline in patients with long-term domiciliary oxygen therapy. (2005) (5)
- Imaging Amyloid Pathology in the Living Brain (2008) (4)
- ACARBOSE ATTENUATES HYPOGLYCEMIA FROM DUMPING SYNDROME IN AN ELDERLY MAN WITH GASTRECTOMY (2005) (4)
- Voxel-Based Morphometry Reveals a Correlation Between Bone Mineral Density Loss and Reduced Cortical Gray Matter Volume in Alzheimer’s Disease (2020) (4)
- CHAPTER 31 – Brain Mapping of the Effects of Aging on Histamine H1 Receptors in Humans: A PET Study with [11C]Doxepin (1998) (4)
- [Cerebrovascular disease and pneumonia in the elderly]. (2003) (4)
- Biomarkers in Subjects with Amnestic Mild Cognitive Impairment (2003) (4)
- A practical method to predict rate of cognitive decline in mild to moderate Alzheimer's disease (1999) (4)
- Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients (2022) (4)
- [Aspiration pneumonia in the elderly]. (2003) (4)
- Lack of association of apolipoprotein E epsilon 4 allele with progressive supranuclear palsy. (1996) (4)
- Computational Analyses of Docosahexaenoic Acid (DHA, C22:6, n-3) with Alzheimer’s Disease-Causing Amyloid Peptide A β 1-42 Reassures Its Therapeutic Utility (2016) (3)
- [Tube feeding in the bedridden elderly patients]. (2009) (3)
- SURVIVAL OF BED‐RIDDEN OLDER PATIENTS (1998) (3)
- Cough and transdermal long-acting beta2 agonist in Japan. (2008) (3)
- S182 and STM2 gene missense mutations in sporadic Alzheimer disease. (1996) (3)
- Quantitative Analysis of Amyloid ß Deposition in Patients with Alzheimer’s Disease Using Positron Emission Tomography (2011) (3)
- Increased protein-conjugated acrolein and beta-amyloid 40/42 ratio in the plasma in patients with mild cognitive impairment and Alzheimer's disease (2012) (3)
- Serum cholesterol and cerebrospinal fluid amyloid beta protein in Alzheimer's disease. (2001) (3)
- Comparison of the Binding Properties of Tau PET Radiotracer 18F-THK523 and Other Amyloid PET Tracers to Alzheimer's Disease Pathology (2013) (3)
- Posterior Associative and Cingulate Cortex Involvement of Brain Single-Photon Emission Computed Tomography (SPECT) Imaging in Semantic Dementia with Probable Alzheimer Disease Pathology: A Case Report (2018) (3)
- APOE epsilon 4 allele in Alzheimer's and non-Alzheimer's dementias. (1996) (3)
- Effects of the Chinese herbal medicine ‘Ba Wei Di Huang Wan’ in the treatment of dementia: A SPECT cerebral blood flow examination and a randomized, double‐blind, placebo‐controlled clinical trial for cognitive function and ADL (2004) (3)
- Assessment of Gait Symmetry in Elderly Women with Low Bone Mineral Density Using a Portable Trunk Accelerometer: A Pilot Study (2019) (3)
- F-SMBT-1 : A Selective and Reversible Positron-Emission Tomography Tracer for Monoamine Oxidase-B Imaging Running title : 18 F-SMBT-1 , a novel MAO-B PET tracer (2020) (3)
- Validation of the binding specificity of Tau PET tracer [18F]THK-5351 on postmortem human brain samples (2015) (3)
- CHANGES IN THE SERUM BONE METABOLISM MARKERS OF ELDERLY ALCOHOLICS DURING ABSTINENCE (2010) (2)
- [Caregiver's burden and use of public services among dementia caregivers]. (2005) (2)
- Adverse motor effects of progressive supranuclear palsy with frontal lobe signs: A case report (2019) (2)
- Prospects for health-systems research (2008) (2)
- Parkinson's disease and impaired chemosensitivity to hypoxia (2000) (2)
- ACCUMULATION OF THE NOVEL TAU IMAGING TRACER 18F-THK-5117 IS ASSOCIATED WITH BRAIN ATROPHY IN ALZHEIMER'S DISEASE (2014) (2)
- Pathobiology of Alzheimer's disease and biomarker development. (2010) (2)
- Early Permeability Change of Macromolecules After Transient Global Ischemia (1985) (2)
- A comprehensive strategy for dementia from primary prevention to end‐stage management (2011) (2)
- Effects of pneumococcal vaccination on hospitalization and exacerbations in elderly Japanese chronic obstructive pulmonary disease patients (2009) (2)
- HERPES SIMPLEX VIRUS AND RISK OF ALZHEIMER'S DISEASE. AUTHORS' REPLY (1997) (2)
- Analysis of early phase [11C]BF-227 PET, and its application for anatomical standardization of late-phase images for 3D-SSP analysis (2014) (2)
- 666 Microtubule-associated protein tau in cerebrospinal fluid: Implications for a potential diagnostic marker in Alzheimer's disease (1996) (2)
- [What we did and learnt in the care of the patients with dementia after the Great East Japan Earthquake in 2011]. (2016) (2)
- [Diagnosing the mild cognitive impairment stage of Alzheimer's disease]. (2004) (2)
- Angiotensin-Converting Enzyme Inhibitors and Smoking Cessation (2007) (2)
- PET imaging with BF-227 in dementia with Lewy bodies (2011) (2)
- Seizure and Pneumonia in an Elderly Patient with Systemic Lupus Erythematosus (2009) (2)
- Transcatheter aortic valve implantation and cognitive function in elderly patients with severe aortic stenosis (2020) (2)
- Confirmation of the Experimentally-Proven Therapeutic Utility of Madecassoside in an Aβ 1-42 Infusion Rat Model of Alzheimer’s Disease by in Silico Analyses (2015) (2)
- [Tau protein in cerebrospinal fluid--a potential marker of Alzheimer's disease]. (1996) (2)
- Classification of the dementias (2003) (2)
- Transcatheter aortic valve implantation improves cognitive function associated with increased cerebral blood flow in elderly patients with severe aortic stenosis. (2020) (2)
- Pitfalls of voxel-based amyloid PET analyses for diagnosis of Alzheimer's disease: artifacts due to non-specific uptake in the white matter and the skull. (2014) (2)
- Development of [ 18 F]SNFT‐1, a novel tau PET tracer with little off‐target binding: Neuroimaging / New imaging methods (2020) (2)
- Validation of the binding specificity of Tau PET tracer [18F]THK-5351 on postmortem human brain samples (2015) (2)
- Noninvasive Detection of Misfolded Proteins in the Brain Using [11C]BF-227 PET (2013) (2)
- Regional Brain Activity and Performance During Car-Driving Under Side Effects of Psychoactive Drugs (2009) (2)
- Defined neurofilament , T , and fi-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques ( cytoskeletal proteins / A 4 protein / neurodegenerative disease ) (2)
- [Clinical heterogeneity in mild cognitive impairment--beyond clinical diagnosis--towards imaging amyloid]. (2004) (1)
- SIGNIFICANCE OF CAROTENOIDS IN RED BLOOD CELLS OF ALZHEIMER'S DISEASE PATIENTS (2014) (1)
- 48. Aspiration Pneumonia (2012) (1)
- Depression in older people (2002) (1)
- Brain Diseases and Aspiration Pneumonia in the Elderly (2002) (1)
- Binding and pharmacokinetic properties of novel 18F-labeled agents for in vivo imaging of tau pathology in Alzheimer's disease (2010) (1)
- α2‐Macroglobulin gene polymorphisms show racial diversity and are not associated with Alzheimer's disease (2000) (1)
- [Neurotransmitter abnormalities in the dementia of Alzheimer type]. (1986) (1)
- Development of geriatric syndromes after taking countermeasures for polypharmacy: an overlooked issue of quitting semiregular single-dose medicine (2019) (1)
- [Importance of vascular aspects in Alzheimer's disease]. (2006) (1)
- [Laboratory and imaging studies for the diagnosis of prion disease]. (2003) (1)
- Rapid Nonradioactive In-Situ Hybridization for mRNA Detection of Calcineurin in Rat Brain Using PCR DNA Probe (2000) (1)
- CSF-phospho-tau as a promising marker for discriminating Alzheimer disease from Lewy body dementia (2000) (1)
- High Correlation among Brain-Derived Major Protein Levels in Cerebrospinal Fluid: Implication for Amyloid-Beta and Tau Protein Changes in Alzheimer’s Disease (2022) (1)
- 2-(2-[2-Dimethylaminothiazol-5-yl]ethenyl)-6-(2-fluoroethoxy)-benzoxazole: A Novel PET Agent for In Vivo Detection of Dense Amyloid Plaques in Alzheimer's Disease Patients (2006) (1)
- BINDING CHARACTERIZATION OF TAU PET TRACER 18F-THK5117 IN NON-ALZHEIMER'S NEURODEGENERATIVE DISEASES (2014) (1)
- P2-056: PET imaging of brain amyloid deposits using BF-227 and its derivative (2008) (1)
- Phenylquinoline derivatives for in vivo imaging of tau pathology in Alzheimer's disease (2011) (1)
- [The benefit of angiotensin converting enzyme inhibitor for geriatric syndrome in the elderly]. (2007) (1)
- In vivo Visualization of α-Synuclein Deposition by [11C]BF-227 PET in Multiple System Atrophy (2009) (1)
- Accidental carbon monoxide poisoning at home in Japan (2007) (1)
- [The measurement of phosphorylated tau in human cerebrospinal fluid as a diagnostic marker for Alzheimer's disease]. (2003) (1)
- PET amyloid imaging in mild cognitive impairment and Alzheimer's disease using novel amyloid ligand [18F]FACT - the hydroxylated BF-227 derivative (2010) (1)
- Characteristics of Respiratory Diseases in Older People (2002) (1)
- Amyloid PET in mild cognitive impairment and Alzheimer's disease with [11C] BF-227: Comparison to voxel-based morphometric MRI (2010) (1)
- The relationships between memory impairment and dense beta-amyloid deposition reflected by BF227 retention (2012) (0)
- P2-145 Novel 18F-labeled pet tracer for detecting amyloid plaques and neurofibrillary tangles in the brain (2004) (0)
- Pet studies of striatal pre-synaptic dopamine uptake in dementia with lewy bodies and Alzheimer's disease (2000) (0)
- [Homicides of disabled older persons by their caregivers and preference for place of death in community-dwelling elderly people in Japan]. (2009) (0)
- P2-320 18F-labeled ethenyl-benzoxazole derivatives for in vivo detection of amyloid plaques in the brain (2006) (0)
- Wavelength-dependent selective detection of tau pathology in Alzheimer's disease using a novel fluorescent probe THK-1188 (2012) (0)
- P2-256 [11C]-BF-227 and PET to visualize amyloid in Alzheimer’s disease patients (2006) (0)
- [Mild cognitive impairment (MCI)--diagnosis and differential diagnosis]. (2004) (0)
- Title Page / Table of Contents, Supplement 1, 1997 (1997) (0)
- GFAP IN THE CEREBROSPINAL FLUID OF AD, DLB, AND FTLD (2014) (0)
- Noninvasive Detection Of α-synuclein Deposits In Human Brain Using [11C]BF227-PET (2009) (0)
- A modified method for 3D-SSP analyses of amyloid PET imaging (2011) (0)
- A Pilot Study of Whole-Brain Low-Intensity Pulsed Ultrasound Therapy for Early Stage of Alzheimer's Disease (LIPUS-AD): A Randomized, Double-Blind, Placebo-Controlled Trial. (2022) (0)
- Erratum to: Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351 (2016) (0)
- IDENTIFICATION OF WAVELENGTH-DEPENDENT COMPOUNDS FOR IMAGING LEWY PATHOLOGY (2016) (0)
- News from the IAG (2000) (0)
- Reviewer ' s report Title : Dietary patterns associated with fall related fracture in elderly Japanese : a population based prospective study Version : 1 Date : 7 September 2009 Reviewer : Marie-Jeanne Kergoat Reviewer ' s report (0)
- Lithium therapy and cerebrospinal fluid biomarker levels in Alzheimer's disease (2005) (0)
- Subject Index Vol. 2, 2005 (2006) (0)
- Handheld computers and electronic medical records systems (2018) (0)
- P3-027 Proteomic analysis of cerebrospinal fluid in Alzheimer's disease (2004) (0)
- [Role of certified geriatric medical doctors in university hospitals in Japan]. (2006) (0)
- POTENTIAL APPLICATION OF 18F-THK5351 AND ITS DERIVATIVES FOR IMAGING ASTROGLIOSIS IN HUMAN BRAIN (2018) (0)
- Presenilin-1 polymorphism and Alzheimer's disease. (1996) (0)
- In vivo imaging of brain amyloid deposits using BF-227 and its derivative (2008) (0)
- Distribution of tau pathology in the patients with mild cognitive impairment and Alzheimer’s disease measured with [18F]THK-5351 PET (2015) (0)
- Analysis of mutation of the tau gene in Alzheimer's disease (2000) (0)
- Amyloid PET Imaging in Idiopathic Normal-Pressure Hydrocephalus (2013) (0)
- [F-18]THK5351 RETENTION IS ASSOCIATED WITH THE PROGRESSION OF BRAIN ATROPHY IN PATIENTS WITH ALZHEIMER’S DISEASE (2016) (0)
- Correlation between Car-draiving Performance and Regional Brain Activity after Oral Administration of a Sedative Antihistamaine (2007) (0)
- Radiation Dosimetry of the F-18 Labelled Amyloid Imaging Probe [18F]FACT in Humans (2013) (0)
- Repetitive pneumonia and wheezing in an elderly patient after radiation therapy (2012) (0)
- Synthesis and Preclinical Evaluation of a Fluorine-18 Labeled BF-227 Derivative (2013) (0)
- Phosphorylated tau protein in cerebrospinal fluid is elevated in Alzheimer's disease and other tauopathies (2000) (0)
- Characteristics of the longitudinal cognitive profile and accumulation of amyloid-beta protein in Alzheimer's disease patients with or without diabetes mellitus (2011) (0)
- Tau positron emission tomography images with a novel tracer, 18F-THK5351, in a patient with progressive supranuclear palsy (2015) (0)
- A study of correlation between the mini mental state examination score, grey matter atrophy and potentially Alzheimer's disease-related plasma biomarkers (2011) (0)
- Effects of Aging on Body Sway during Upright Standing in the patients with Dizziness and Associated Disorders (1998) (0)
- Characteristics of the baseline plasma homocysteine levels and the correlation with risk factors and cognition in Japanese-ADNI (J-ADNI) biomarker study (2010) (0)
- [The trend of developing new disease-modifying drugs in Alzheimer's disease]. (2016) (0)
- Assessment of Nigrostriatal Dopaminergic Function in Patients with Dementia with Lewy Bodies (2000) (0)
- Development of selective tau and MAO-B PET tracers through compound optimization of 18 F-THK5351 (2018) (0)
- Discussions on phosphorylated tau and other biochemical markers (2004) (0)
- Brain-Derived Major Glycoproteins Are Possible Biomarkers for Altered Metabolism of Cerebrospinal Fluid in Neurological Diseases (2023) (0)
- Amyloid PET and Voxel-based Morphometry Analysis Using MRI in Mild Cognitive Impairment and Alzheimer's Disease (2008) (0)
- Disaster medicine for the elderlies -chronological aspects of the Great East Japan Earthquake and Tsunami and future issues. (2017) (0)
- VIII. 4. Amyloid Imaging in MCI and Alzheimer's Disease with BF-227, a New PET Tracer: Comparison to FDG-PET (2009) (0)
- MRI using a voxel-based specific regional analysis system for Alzheimer's disease and magnetic resonance spectroscopy are useful methods for routine management of Alzheimer's disease (2013) (0)
- Role for Peroxisome Proliferator-Activated Receptor-g in Alzheimer’s Disease (2001) (0)
- Quantitative Analysis of Amyloid Beta Deposition in the Brain of Alzheimer’s Disease Patients Using PET and [11C]BF-227 and [18F]FACT (2010) (0)
- PET imaging for mild cognitive impairment with FDG and beta-amyloid tracer, 11C-BF-227 (2009) (0)
- P3-033 Cerebrospinal fluid Tau and periventricular white matter lesions in stable and progressive mild cognitive impairment (2004) (0)
- Leptin and adiponectin in plasma and CSF from Alzheimer's patients and normal controls (2009) (0)
- Subject Index Vol. 46, 2000 (2000) (0)
- Author ' s response to reviews Title : Dietary patterns associated with fall related fracture in elderly Japanese : a population based prospective study (2009) (0)
- 3-12-03 A positron emission tomographic analysis of changes in the striatal dopamine D2 receptor binding during the advances of Alzheimer's disease and vascular dementia (1997) (0)
- [F-18]THK5351 RETENTION IS ASSOCIATED WITH THE PROGRESSION OF BRAIN ATROPHY IN PATIENTS WITH ALZHEIMER’S DISEASE (2016) (0)
- FDG-PET Study of Patient with a Novel Presenilin4 Mutation in the Mild Cognitive Impairment Stage of Aizheimer's Disease (2001) (0)
- PET imaging for mild cognitive impairment with FDG and beta-amyloid tracer, 11C-BF-227 (2009) (0)
- [Genetic risk factors in senile dementia]. (1999) (0)
- Relationship between Cerebral Glucose Metabolism and CSF Markers in Neurodegenerative Dementia (1999) (0)
- Comparison of the binding characteristics of [¹⁸F]SNFT-1 and other tau imaging tracers to Alzheimer's disease pathology (2022) (0)
- Legends Suppl Tables (2014) (0)
- PET with Beta-Amyloid Tracer, 11C-BF-227 in MCI and Alzheimer's Disease: Comparison to Biofluid Biomarkers (2010) (0)
- A Glycan Marker for Idiopathic Normal Pressure Hydrocephalus (2014) (0)
- Characterization of β-sheet ligand positive astrocytosis found in Frontotemporal lobar degeneration TDP-43 type-A (2021) (0)
- A comparison of human observers and a channelized Hotelling observer in discriminating between Alzheimer's dementia and controls using brain perfusion SPECT (2005) (0)
- P4-337 Cognition and long term donepezil use in Alzheimer’s disease (2006) (0)
- Discriminant power of a combination of IMP-SPECT and CSF-tau protein in the early diagnosis of Alzheimer's disease (2000) (0)
- Benefit of herbal medicine use in donepezil-treated Alzheimer’s disease patients (2005) (0)
- P2-055: Noninversive detection of amyloid deposits by near-infrared fluorescence probe THK-265 (2008) (0)
- The earthquake- and tsunami-exacerbated dementia in Japan (2012) (0)
- AO-01-1 Efficacy of bone marrow transplantation for adolescent/ adult-onset cerebral/cerebello-brainstem ALD Serum and neurofilament light as in AO-01-5 Voxel-based QSM analysis as an imaging biomarker for mild cognitive impairment in Parkinson disease (2019) (0)
- [Pre-symptomatic detection of Alzheimer's disease and mild cognitive impairment]. (2009) (0)
- Cerebrospinal fluid phosphorylated tau protein at serine 199 is a useful diagnostic biomarker in Alzheimer’s disease and mild cognitive impairment (2005) (0)
- The binding of beta-amyloid 42 to lipid rafts containing detergent-resistant membranes of RBC ghost is enhanced by dietary docosahexaenoic acid in rats: An implication of erythrocyte functions to Alzheimer's disease (2013) (0)
- An Approach to Establish Antemortem Diagnosis of Dementia with Lewy Bodies (2002) (0)
- Brain Accumulation of Amyloid Protein Visualized by PET and BF-227 in Alzheimer's Disease Patients with or without Diabetes Mellitus (2015) (0)
- P4-275 Uncaria rhynchophylla, a Chinese medicinal herb, has potent anti-aggregation effects on Alzheimer’s amyloid β proteins (2006) (0)
- DEVELOPMENT OF A NOVEL 18F-LABELED PET TRACER FOR IMAGING ASTROGLIOSIS (2019) (0)
- LONGITUDINAL ASSESSMENT OF [18F]THK-5351 ACCUMULATION IN PATIENTS WITH ALZHEIMER’S DISEASE (2017) (0)
- INCREASED RISK FOR SILENT BRAIN INFARCTION AND DEEP WHITE MATTER LESION IN ALCOHOLIC PATIENTS. (2004) (0)
- DEVELOPMENT OF A NOVEL 18F-LABELED PET TRACER FOR IMAGING ASTROGLIOSIS (2019) (0)
- Centrally Active ACEIs and cognitive decline. (2010) (0)
- POTENTIAL APPLICATION OF 18F-THK5351 AND ITS DERIVATIVES FOR IMAGING ASTROGLIOSIS IN HUMAN BRAIN (2018) (0)
- Applicaton of An Artificial Neural Network to Generation of Parametric Images in A [11C]Doxepin-PET Study (1997) (0)
- In vitro comparative binding studies: Amyloid and tau imaging probes (2011) (0)
- Distribution of tau pathology in patients with mild cognitive impairment and Alzheimer’s disease measured with [18F]THK-5351 PET (2015) (0)
- [Pneumonia in the older people]. (1999) (0)
- Discovery and evaluation of a novel tau PET tracer [18F]THK-5562 for Alzheimer's disease (2020) (0)
- Relationships between Cognitive Ability and Driving Behavior in Elderly People : Using Trail Making Test and a Driving Simulator (2002) (0)
- The interaction of beta-amyloid with alpha1-chimaerin involved in the pathogenesis of Alzheimer's disease (2011) (0)
- The first autopsy report from J-ADNI (2013) (0)
- Voxel-based analyses of amyloid PET using BF-227. Differences in results of 3D-SSP and SPM-based methods (2012) (0)
- CSF TAU IS ELEVATED IN ALCOHOLICS WITH WERNICKE???S ENCEPHALOPATHY. (2004) (0)
- articleDietary patterns associated with fall-related fracture in elderly Japanese : a population based prospective study (2015) (0)
- On the Helmasperger Notarial Instrument: Translation and Interpretation (2018) (0)
- Regional Glucose Hypometabolism in Brain of Patients with Dementia with Lewy Bodies and Alzheimer's Disease (2000) (0)
- Development of [18F]SNFT‐1, a novel tau PET tracer with little off‐target binding (2020) (0)
- P2260Impacts of hippocampal blood flow on cardiac remodeling in patients with chronic heart failure (2019) (0)
- [11C]BF-227 PET study in patients with dementia with Lewy bodies (2012) (0)
- Development of candidate biomarkers for dementia: Cerebrospinal fluid-specific carbohydrate side chains (2010) (0)
- Olfactory Stimulation and Dysphagia in the Elderly (2008) (0)
- Quantification of Striatal Dopamine D2 Receptors in Normal Aging and Dementia Using PET and [11C]YM-09151-2 (1996) (0)
- COMPARISON OF 18F-THK5117 AND 11C-PIB PET IMAGES IN PATIENTS WITH ALZHEIMER'S DISEASE (2014) (0)
- [Clinical diagnosis, treatment and prevention of aspiration pneumonia]. (2011) (0)
- [Diagnosis and treatment of dementia: overview]. (2014) (0)
- Immunogenetherapy of Cancer Using Recombinant Adenovirus Expressing Type III interferon IL-28A or IL-29 (2016) (0)
- Characterization of a novel monoamine oxidase-B tracer [18F]SMBT-1 for imaging of reactive astrocytes (2021) (0)
- Contents Vol. 46, 2000 (2000) (0)
- Binding characterization of novel PET tracer [18F]THK-5117 in the brains of people with Alzheimer's disease (2013) (0)
- Impact on management of new diagnostic tests in Alzheimer's disease (1996) (0)
- AM-12 Natural products (2007) (0)
- P3-011: Antihypertensive drug use modulates progression of Alzheimer's disease (2008) (0)
- 542 Immunohistochemical study of apolipoprotein E (ApoE) in Alzheimer's disease by the confocal scanning laser microscope (1996) (0)
- Influences of Apolipoprotein E and α1-Antichymotrypsin Genotypes on Regional Cerebral Glucose Metabolism in Alzheimer's Disease (1996) (0)
- Functional Decline After an Emergency Shelter Stay: Misleading Evidence (2012) (0)
- Quantification of Amyloid β Deposition in Alzheimer's Disease Patients Using PET and [11C]BF-227 (2009) (0)
- Contents Vol. 2, 2005 (2006) (0)
- Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy (2018) (0)
- [The prevention of pneumonia in the elderly by dopamine agonists]. (2001) (0)
- IC-P2-122: PET imaging of brain amyloid deposits using BF-227 and its derivative (2008) (0)
- JAD140225 Miyashita TREM2 14-0225r1 140310 (2014) (0)
- Subject Index Vol. 56, 2010 (2010) (0)
- S1-01-04: BF-227 amyloid imaging in patients with Alzheimer's disease (2008) (0)
- S-II-16. Evalution of shunt Therapy Related to Etiology and Cerebral Demage in Normal Pressure Hydrocephalus (1972) (0)
- Contents Vol. 56, 2010 (2010) (0)
- Near-infrared fluorescence probe X50 for in vivo detection of amyloid plaques in the brain (2011) (0)
- [From neuropathology to biomarker development in Alzheimer research]. (2006) (0)
- LETTER TO THE EDITOR (2002) (0)
- Cerebral Muscarinic Acetylcholine Receptor Binding is Associated with the Severity of Dementia: A [11C]benztropine-PET Study in Alzheimer's Disease (1996) (0)
- [Progress in the field of pulmonary medicine in the last 100 years: Medical history of aspiration pneumonitis]. (2002) (0)
- [Biomarkers, mild cognitive impairment and early diagnosis of Alzheimer's disease]. (2003) (0)
- SUCCESSFUL REDUCTION OF OFF-TARGET BINDING OF QUINOLINE DERIVATIVES AS TAU-SELECTIVE PET TRACERS (2017) (0)
- Vulnerability of the Neuronal Cytoskeleton in Aging and Alzheimer Disease: Widespread Involvement of All Three Major Filament Systems (1990) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Hiroyuki Arai?
Hiroyuki Arai is affiliated with the following schools:
