Hiroyuki Arai
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Computer Science
Hiroyuki Arai's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Hiroyuki Arai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production (2002) (892)
- Affinity for α‐tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs (1997) (603)
- Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (2002) (544)
- Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid* (1999) (505)
- Ataxia with isolated vitamin E deficiency is caused by mutations in the α–tocopherol transfer protein (1995) (502)
- LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing (2005) (495)
- Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor (1994) (470)
- Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid* (2006) (452)
- Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. (2012) (445)
- Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways* (2002) (401)
- The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza (2013) (395)
- Activation of STING requires palmitoylation at the Golgi (2016) (322)
- Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1* (2004) (280)
- TGFα shedding assay: an accurate and versatile method for detecting GPCR activation (2012) (272)
- Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition (2013) (266)
- CD36, a Member of the Class B Scavenger Receptor Family, as a Receptor for Advanced Glycation End Products* (2001) (255)
- Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress (2001) (250)
- Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species (2000) (250)
- Autotaxin Is Overexpressed in Glioblastoma Multiforme and Contributes to Cell Motility of Glioblastoma by Converting Lysophosphatidylcholine TO Lysophosphatidic Acid* (2006) (238)
- Regulation and Function of Versatile Aerobic and Anaerobic Respiratory Metabolism in Pseudomonas aeruginosa (2011) (233)
- Topography and subunit stoichiometry of the coated vesicle proton pump. (1988) (226)
- Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response* (2010) (225)
- Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages. (1990) (219)
- The MAP1-LC3 conjugation system is involved in lipid droplet formation. (2009) (218)
- Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. (1995) (217)
- Phenotypic Modulation of Vascular Smooth Muscle Cells Induced by Unsaturated Lysophosphatidic Acids (2001) (204)
- Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid* (2012) (203)
- The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury (2009) (202)
- Expression Cloning of a Novel Scavenger Receptor from Human Endothelial Cells* (1997) (192)
- ABCA3 as a Lipid Transporter in Pulmonary Surfactant Biogenesis* (2007) (189)
- Molecular mechanisms of vitamin E transport. (1999) (188)
- A Novel Phosphatidic Acid-selective Phospholipase A1That Produces Lysophosphatidic Acid* (2002) (186)
- Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. (1995) (185)
- Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1s⃞ Published, JLR Papers in Press, May 15, 2006. (2006) (184)
- Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C (2007) (181)
- DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. (2006) (177)
- α-Tocopherol Transfer Protein Is Important for the Normal Development of Placental Labyrinthine Trophoblasts in Mice* (2001) (177)
- Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport Is Inhibited by Advanced Glycation End Products* (2001) (175)
- Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. (1992) (174)
- Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer (1997) (172)
- The Anaerobic Regulatory Network Required for Pseudomonas aeruginosa Nitrate Respiration (2007) (171)
- Purification and characterization of the α‐tocopherol transfer protein from rat liver (1991) (169)
- Different functional aspects of the group II subfamily (Types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation. (1999) (163)
- Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. (2000) (158)
- Purification and characterization of bovine brain platelet-activating factor acetylhydrolase. (1993) (156)
- Vitamin E decreases bone mass by stimulating osteoclast fusion (2012) (155)
- Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer (2004) (154)
- Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes (2011) (148)
- SRB1, a class B scavenger receptor, recognizes both negatively charged liposomes and apoptotic cells. (1996) (148)
- Expression of the nir and nor genes for denitrification of Pseudomonas aeruginosa requires a novel CRP/FNR‐related transcriptional regulator, DNR, in addition to ANR (1995) (147)
- Primary structure of alpha-tocopherol transfer protein from rat liver. Homology with cellular retinaldehyde-binding protein. (1993) (145)
- Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family. (2007) (141)
- Cascade regulation of the two CRP/FNR‐related transcriptional regulators (ANR and DNR) and the denitrification enzymes in Pseudomonas aeruginosa (1997) (140)
- Fibrates Down-regulate Hepatic Scavenger Receptor Class B Type I Protein Expression in Mice* (2003) (139)
- Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains (2017) (137)
- ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells Published, JLR Papers in Press, October 17, 2005. (2006) (137)
- Serine Phospholipid-specific Phospholipase A That Is Secreted from Activated Platelets (1997) (134)
- Miller-Dicker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase (1994) (134)
- Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice (2011) (134)
- CD36, serves as a receptor for advanced glycation endproducts (AGE). (2002) (129)
- Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide β-1,4-Galactosyltransferase from Rat Brain* (1998) (129)
- Protection against Oxidative Stress-induced Cell Death by Intracellular Platelet-activating Factor-Acetylhydrolase II* (1997) (123)
- Friedreich‐like ataxia with retinitis pigmentosa caused by the His101Gln mutation of the α‐Tocopherol transfer protein gene (1997) (122)
- 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload–induced maladaptive cardiac remodeling (2014) (122)
- Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol. (2007) (122)
- Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding (2008) (121)
- LPA‐producing enzyme PA‐PLA1α regulates hair follicle development by modulating EGFR signalling (2011) (120)
- Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling (2018) (119)
- Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma (2004) (119)
- Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells. (2005) (117)
- The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase. (1994) (117)
- Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma (2004) (117)
- Vitamin E and transfer proteins (2003) (115)
- The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site (2003) (114)
- Impaired α-TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency (2013) (114)
- Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, blocks lysosomal cholesterol trafficking in macrophages. (1993) (114)
- Biochemical and Molecular Characterization of a Novel Choline-specific Glycerophosphodiester Phosphodiesterase Belonging to the Nucleotide Pyrophosphatase/Phosphodiesterase Family* (2005) (110)
- Structure and function of phosphatidylserine-specific phospholipase A1. (2002) (109)
- LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice (2012) (107)
- Platelet-activating factor acetylhydrolase (PAF-AH). (2002) (107)
- Purification and Characterization of Platelet-activating Factor Acetylhydrolase II from Bovine Liver Cytosol (*) (1995) (106)
- LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. (2010) (106)
- α -Tocopherol Transfer Protein Stimulates the Secretion of α -Tocopherol from a Cultured Liver Cell Line through a Brefeldin A-Insensitive Pathway (1997) (106)
- Differential expression of multiple terminal oxidases for aerobic respiration in Pseudomonas aeruginosa. (2009) (105)
- Three of the seven bphC genes of Rhodococcus erythropolis TA421, isolated from a termite ecosystem, are located on an indigenous plasmid associated with biphenyl degradation (1997) (105)
- Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase (2015) (104)
- SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. (2002) (104)
- Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation (2014) (103)
- Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity. (2007) (103)
- Vascular Remodeling Induced by Naturally Occurring Unsaturated Lysophosphatidic Acid In Vivo (2003) (102)
- Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut (2015) (101)
- Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators (2013) (101)
- Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. (2008) (100)
- Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis (2001) (99)
- Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma. (2013) (98)
- Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice1 (2007) (98)
- Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain‐specific MMP highly expressed in cerebellum (2001) (96)
- Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction* (2006) (95)
- Dissociation, cross-linking, and glycosylation of the coated vesicle proton pump. (1990) (95)
- Localization of α-tocopherol transfer protein in rat brain (1998) (94)
- Transcriptional regulation of the nos genes for nitrous oxide reductase in Pseudomonas aeruginosa. (2003) (94)
- Interaction of anions and ATP with the coated vesicle proton pump. (1989) (94)
- Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. (2006) (93)
- A Novel Phospholipase A1 with Sequence Homology to a Mammalian Sec23p-interacting Protein, p125* (2002) (92)
- Adaptation of Comamonas testosteroni TA441 to utilize phenol: organization and regulation of the genes involved in phenol degradation. (1998) (89)
- SREC-II, a New Member of the Scavenger Receptor Type F Family, Trans-interacts with SREC-I through Its Extracellular Domain* (2002) (89)
- Transcriptional Regulation of the Flavohemoglobin Gene for Aerobic Nitric Oxide Detoxification by the Second Nitric Oxide-Responsive Regulator of Pseudomonas aeruginosa (2005) (88)
- Inhibition of the coated vesicle proton pump and labeling of a 17,000-dalton polypeptide by N,N'-dicyclohexylcarbodiimide. (1987) (88)
- Gene cluster for dissimilatory nitrite reductase (nir) from Pseudomonas aeruginosa: sequencing and identification of a locus for heme d1 biosynthesis (1997) (88)
- Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution. (1998) (87)
- Subunit composition and ATP site labeling of the coated vesicle proton-translocating adenosinetriphosphatase. (1987) (87)
- Biochemical and Molecular Characterization of Two Phosphatidic Acid-selective Phospholipase A1s, mPA-PLA1α and mPA-PLA1β* (2003) (87)
- cDNA Cloning and Expression of Intracellular Platelet-activating Factor (PAF) Acetylhydrolase II (1996) (86)
- Targeted Disruption of Intracellular Type I Platelet Activating Factor-acetylhydrolase Catalytic Subunits Causes Severe Impairment in Spermatogenesis* (2003) (86)
- Enzymatic Characterization and In Vivo Function of Five Terminal Oxidases in Pseudomonas aeruginosa (2014) (85)
- Autotaxin Regulates Vascular Development via Multiple Lysophosphatidic Acid (LPA) Receptors in Zebrafish* (2011) (85)
- Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA‐binding proteins in activation of LPA receptors (2002) (85)
- Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE (2000) (84)
- Regulation of Pseudomonas aeruginosa hemF and hemN by the dual action of the redox response regulators Anr and Dnr (1998) (84)
- Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples. (2018) (83)
- Expression patterns of the lysophospholipid receptor genes during mouse early development (2008) (83)
- Purification, microheterogeneity, and stability of human lipid transfer protein. (1989) (82)
- CO2-Responsive Expression and Gene Organization of Three Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase Enzymes and Carboxysomes in Hydrogenovibrio marinus Strain MH-110 (2004) (82)
- Bile salt–dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4 (2007) (81)
- Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis (2014) (80)
- Coexistence of Antibiotic-Producing and Antibiotic-Sensitive Bacteria in Biofilms Is Mediated by Resistant Bacteria (2008) (80)
- Cholesterol ester transfer mediated by lipid transfer protein as influenced by changes in the charge characteristics of plasma lipoproteins. (1993) (79)
- Cloning and Expression of a cDNA Encoding the -Subunit (30-kDa Subunit) of Bovine Brain Platelet-activating Factor Acetylhydrolase (*) (1995) (79)
- Meta-cleavage enzyme gene tesB is necessary for testosterone degradation in Comamonas testosteroni TA441. (2001) (78)
- Membrane lipid saturation activates IRE1α without inducing clustering (2013) (77)
- Arrangement and regulation of the genes for meta-pathway enzymes required for degradation of phenol in Comamonas testosteroni TA441. (2000) (76)
- Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. (1996) (75)
- Postmortem study of ataxia with retinitis pigmentosa by mutation of the α-tocopherol transfer protein gene (2000) (74)
- Switching of Platelet-activating Factor Acetylhydrolase Catalytic Subunits in Developing Rat Brain* (1998) (73)
- Phosphatidylserine-specific Phospholipase A1Stimulates Histamine Release from Rat Peritoneal Mast Cells through Production of 2-Acyl-1-lysophosphatidylserine* (2001) (72)
- Visualization of the heterogeneous membrane distribution of sphingomyelin associated with cytokinesis, cell polarity, and sphingolipidosis (2015) (71)
- Intracellular Transport of Fat‐Soluble Vitamins A and E (2015) (71)
- Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy (2012) (71)
- Identification of a Novel Member of the Carboxylesterase Family That Hydrolyzes Triacylglycerol (2006) (70)
- Protection against Oxidative Stress-induced Hepatic Injury by Intracellular Type II Platelet-activating Factor Acetylhydrolase by Metabolism of Oxidized Phospholipids in Vivo* (2008) (70)
- Total synthesis and bioactivity of resolvin E2. (2009) (69)
- Member of the membrane‐bound O‐acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity (2008) (69)
- Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A2* (2005) (69)
- Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells. (2004) (69)
- α-Tocopherol Transfer Protein Is Specifically Localized at the Implantation Site of Pregnant Mouse Uterus (2002) (69)
- Nerve Growth Factor Activates Mast Cells Through the Collaborative Interaction with Lysophosphatidylserine Expressed on the Membrane Surface of Activated Platelets1 (2002) (68)
- Complete inhibition of mouse macrophage-derived foam cell formation by triacsin C. (1999) (68)
- Cyclic Phosphatidic Acid Is Produced by Autotaxin in Blood* (2006) (67)
- Structure-activity relationships of fluorinated lysophosphatidic acid analogues. (2005) (66)
- Expression of cholesteryl ester transfer protein in human atherosclerotic lesions and its implication in reverse cholesterol transport. (2001) (66)
- Multivesicular Body Formation Requires OSBP–Related Proteins and Cholesterol (2010) (66)
- Stabilization of Pseudomonas aeruginosa Cytochromec 551 by Systematic Amino Acid Substitutions Based on the Structure of Thermophilic Hydrogenobacter thermophilus Cytochrome c 552 * (1999) (66)
- LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover (2020) (65)
- The structural genes for nitric oxide reductase from Pseudomonas aeruginosa. (1995) (65)
- Group VIB Ca2+-independent Phospholipase A2γ Promotes Cellular Membrane Hydrolysis and Prostaglandin Production in a Manner Distinct from Other Intracellular Phospholipases A2* (2005) (64)
- Effect of nitrogen oxides on expression of the nir and nor genes for denitrification in Pseudomonas aeruginosa. (1999) (63)
- pH‐dependent translocation of α‐tocopherol transfer protein (α‐TTP) between hepatic cytosol and late endosomes (2003) (63)
- Biochemical Characterization of Various Catalytic Complexes of the Brain Platelet-activating Factor Acetylhydrolase* (1999) (63)
- Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme. (2001) (63)
- Two Very Long Chain Fatty Acid Acyl-CoA Synthetase Genes, acs-20 and acs-22, Have Roles in the Cuticle Surface Barrier in Caenorhabditis elegans (2010) (62)
- Synthesis and evaluation of lysophosphatidylserine analogues as inducers of mast cell degranulation. Potent activities of lysophosphatidylthreonine and its 2-deoxy derivative. (2009) (61)
- Structure and ANR-dependent transcription of the nir genes for denitrification from Pseudomonas aeruginosa. (1994) (61)
- Retinitis pigmentosa and ataxia caused by a mutation in the gene for the alpha-tocopherol-transfer protein. (1996) (60)
- Transcriptome response to different carbon sources in Acetobacter aceti. (2011) (60)
- Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3. (2013) (59)
- An Alternative Splicing Form of Phosphatidylserine-specific Phospholipase A1 That Exhibits Lysophosphatidylserine-specific Lysophospholipase Activity in Humans* (1999) (59)
- Scavenger Receptor Expressed by Endothelial Cells I (SREC-I) Mediates the Uptake of Acetylated Low Density Lipoproteins by Macrophages Stimulated with Lipopolysaccharide* (2004) (58)
- Scavenger cells with gram-positive bacterial lipoteichoic acid infiltrate around the damaged interlobular bile ducts of primary biliary cirrhosis. (2001) (58)
- Proteolysis and orientation on reconstitution of the coated vesicle proton pump. (1990) (58)
- Measurement of lysophospholipase D/autotaxin activity in human serum samples. (2007) (56)
- Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency. (2014) (56)
- Stearoyl-CoA Desaturase 1 Activity Is Required for Autophagosome Formation* (2014) (56)
- CD36, a Member of Class B Scavenger Receptor Family, Is a Receptor for Advanced Glycation End Products (2001) (55)
- Transcriptome Dynamics during the Transition from Anaerobic Photosynthesis to Aerobic Respiration in Rhodobacter sphaeroides 2.4.1 (2007) (55)
- Functional hemizygosity of PAFAH1B3 due to a PAFAH1B3-CLK2 fusion gene in a female with mental retardation, ataxia and atrophy of the brain. (2001) (54)
- Matrix Metalloproteinase (MMP)-9 in Cancer-Associated Fibroblasts (CAFs) Is Suppressed by Omega-3 Polyunsaturated Fatty Acids In Vitro and In Vivo (2014) (54)
- Human Placental Trophoblast Cells Express α-Tocopherol Transfer Protein (2003) (54)
- Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity. (2007) (54)
- Maternal dietary imbalance between omega‐6 and omega‐3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites (2016) (54)
- Platelet-activating factor acetylhydrolase. (2002) (53)
- Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1. (2005) (53)
- Inhibition of cholesterol biosynthesis by 25‐hydroxycholesterol is independent of OSBP (2005) (52)
- Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor , EDG 7 , for Lysophosphatidic Acid * (1999) (51)
- MBR-1, a Novel Helix-Turn-Helix Transcription Factor, Is Required for Pruning Excessive Neurites in Caenorhabditis elegans (2005) (51)
- The binding of TBK1 to STING requires exocytic membrane traffic from the ER. (2018) (51)
- Intracellular Phospholipase A1γ (iPLA1γ) Is a Novel Factor Involved in Coat Protein Complex I- and Rab6-independent Retrograde Transport between the Endoplasmic Reticulum and the Golgi Complex* (2009) (51)
- Homeostatic regulation of STING by retrograde membrane traffic to the ER (2021) (51)
- Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase (2016) (50)
- Anti-apoptotic Actions of the Platelet-activating Factor Acetylhydrolase I α2 Catalytic Subunit* (2004) (50)
- The novel genes, cbbQ and cbbO, located downstream from the RubisCO genes of Pseudomonas hydrogenothermophila, affect the conformational states and activity of RubisCO. (1997) (50)
- PAF analogues capable of inhibiting PAF acetylhydrolase activity suppress migration of isolated rat cerebellar granule cells (1997) (49)
- Squalene as a target molecule in skin hyperpigmentation caused by singlet oxygen. (2009) (49)
- LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice[S] (2012) (49)
- Purification and characterization of the alpha-tocopherol transfer protein from rat liver. (1991) (49)
- Two c-type cytochromes, NirM and NirC, encoded in the nir gene cluster of Pseudomonas aeruginosa act as electron donors for nitrite reductase. (2001) (49)
- Intracellular Phospholipase A1 and Acyltransferase, Which Are Involved in Caenorhabditis elegans Stem Cell Divisions, Determine the sn-1 Fatty Acyl Chain of Phosphatidylinositol (2010) (48)
- Type F Scavenger Receptor SREC-I Interacts with Advillin, a Member of the Gelsolin/Villin Family, and Induces Neurite-like Outgrowth* (2004) (48)
- Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus. (2006) (47)
- ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion. (2010) (47)
- Apolipoprotein E enhances lipid exchange between lipoproteins mediated by cholesteryl ester transfer protein. (1993) (47)
- Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution (2019) (47)
- Characterization of a Bifunctional Archaeal Acyl Coenzyme A Carboxylase (2003) (46)
- Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth (2013) (46)
- Vitamin E Is Essential for Mouse Placentation but Not for Embryonic Development Itself (2005) (45)
- Mitochondria‐type GPAT is required for mitochondrial fusion (2013) (45)
- Binding of α‐tocopherylquinone, an oxidized form of α‐tocopherol, to glutathione‐S‐transferase in the liver cytosol (1998) (45)
- Binding of pleckstrin homology domains to WD40/beta-transducin repeat containing segments of the protein product of the Lis-1 gene. (1995) (45)
- Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P2 Synthesis (2019) (44)
- Identification of platelet-activating factor acetylhydrolase II in human skin. (2002) (44)
- alpha-tocopherol transfer protein stimulates the secretion of alpha-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway. (1997) (44)
- β-Catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions (2008) (42)
- Subcellular localization of sphingomyelin revealed by two toxin‐based probes in mammalian cells (2012) (42)
- Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441. (1999) (42)
- Omega-3 Polyunsaturated Fatty Acids Suppress the Cystic Lesion Formation of Peritoneal Endometriosis in Transgenic Mouse Models (2013) (41)
- Analysis of lissencephaly-causing LIS1 mutations. (1999) (40)
- Widespread expression of alpha-synuclein and tau immunoreactivity in Hallervorden-Spatz syndrome with protracted clinical course. (2000) (40)
- Changes in the gene expression profile of Acetobacter aceti during growth on ethanol. (2012) (39)
- Establishment of anti-human cholesteryl ester transfer protein monoclonal antibodies and radioimmunoassaying of the level of cholesteryl ester transfer protein in human plasma. (1992) (39)
- Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver Published, JLR Papers in Press, June 1, 2006. (2006) (39)
- Effect of α-Tocopherol Status on α-Tocopherol Transfer Protein Expression and Its Messenger RNA Level in Rat Liver (1998) (39)
- cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues. (1995) (39)
- Identifying specific conformations by using a carbohydrate scaffold: discovery of subtype-selective LPA-receptor agonists and an antagonist. (2004) (39)
- Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones. (1999) (39)
- Differential expression of lysophosphatidic acid receptor‐2 in intestinal and diffuse type gastric cancer (2006) (39)
- Altered vitamin E status in Niemann-Pick type C disease (2011) (38)
- Eicosapentaenoic acid is converted via ω‐3 epoxygenation to the anti‐inflammatory metabolite 12‐hydroxy‐17,18‐epoxyeicosatetraenoic acid (2014) (38)
- Anabolic five subunit-type pyruvate:ferredoxin oxidoreductase from Hydrogenobacter thermophilus TK-6. (2006) (38)
- Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation (2017) (38)
- Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. (2003) (38)
- A Soluble NADH-Dependent Fumarate Reductase in the Reductive Tricarboxylic Acid Cycle of Hydrogenobacter thermophilus TK-6 (2008) (38)
- Cloning and sequencing of the gene encoding cytochrome c‐551 from Pseudomonas aeruginosa (1990) (38)
- The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic (2017) (37)
- Damaged interlobular bile ducts in primary biliary cirrhosis show reduced expression of glutathione-S-transferase-pi and aberrant expression of 4-hydroxynonenal. (2002) (37)
- Lysophosphatidylcholine export by human ABCA7. (2017) (37)
- Genes encoding RubisCO in Pseudomonas hydrogenothermophila are followed by a novel cbbQ gene similar to nirQ of the denitrification gene cluster from Pseudomonas species. (1995) (37)
- Complete Genome Sequence of the Thermophilic, Obligately Chemolithoautotrophic Hydrogen-Oxidizing Bacterium Hydrogenobacter thermophilus TK-6 (2010) (37)
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- Localization of alpha-tocopherol transfer protein in rat brain. (1998) (35)
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- he cbbQ Genes, Located Downstream of the Form I nd Form II RubisCO Genes, Affect the Activity f Both RubisCOs (1999) (2)
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- Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking (2022) (0)
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- To clarify how Reelin affects the lipid composition of neurons (2017) (0)
- Acyl Coenzyme A Carboxylase Characterization of a Bifunctional Archaeal (2003) (0)
- Molecular and biological characterization of choline-specific lysophospholipase C, NPP6 (2006) (0)
- RSD-3, a C. elegans homolog of epsinR, is important for cellular uptake of silencing RNA in both somatic and germ cells (2016) (0)
- Implications of cholesterol and sphingomyelin in STING phosphorylation by TBK1 (2021) (0)
- Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from Hydrogenobacter thermophilus TK-6 in Complex with L-phosphoserine (2013) (0)
- [Regulation of the vitamin E level in the body by alpha-TTP, alpha-tocopherol-specific transfer protein]. (2014) (0)
- LIMITED EXCHANGE OF HISTONE VARIANT H2A.Z IN DYNAMIC NUCLEOSOMES OF NON-REPLICATING CELLS (2013) (0)
- P-183 Fitness effects of pellicle formation in aerobic bacteria(Poster Session) (2010) (0)
- evectin-2 regulates RE localization of Nedd4 family E3 ligases (2016) (0)
- The mechanism underlying the activation of STING variants associated with an autoinflammatory disease SAVI (2017) (0)
- Role of Nitric Oxide-Detoxifying Enzymes in the Virulence of Pseudomonas aeruginosa against the Silkworm, Bombyx mori (2013) (0)
- Structural Insights into the Phospholipid Binding Specificity of Human Evectin-2 (2012) (0)
- Identification and Characterization of a PDZ Domain-containing Protein That Interacts with the HDL Receptor SR-BI (2000) (0)
- TOPOGRAPHICAL ANALYSIS FOR COATED VESICLE H+-ATPASE DERIVED FROM CALF BRAIN (1991) (0)
- The sn-1 fatty acid composition of phosphatidylinositol is important for the integrity of apical junctions between epidermal cells (2017) (0)
- 2P-129 Carbon utilization in chemolithoautotrophs Hydrogenophilus thermoluteolus TH-1 (2013) (0)
- Clarification of the role of Reelin on lipid quality of brain (2016) (0)
- Deficiency of polyunsaturated fatty acids (PUFAs) induces the G1/S cell cycle arrest (2017) (0)
- Structure and Function of Human SREC (Scavenger Receptor expressed by Endothelial Cells), A Novel Receptor for Modified LDL (2000) (0)
- Type II platelet‐activating factor‐acetylhydrolase is essential for epithelial morphogenesis in C. elegans (2006) (0)
- Development of polyunsaturated fatty acids (PUFAs)-deficient cells in culture. (2016) (0)
- X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) (2000) (0)
- Crystal Structure of a Novel-type Phosphoserine Phosphatase from Hydrogenobacter thermophilus TK-6 (2013) (0)
- Erratum: Role of nitric oxide-detoxifying enzymes in the virulence of pseudomonas aeruginosa against the silkworm, bombyx mori (Bioscience, Biotechnology and Biochemistry (2013) 77:1 (199)) (2013) (0)
- Protective role of PAF-AH2, an oxidized phospholipid-selective phospholipase, in high-fat diet-induced fatty liver (2016) (0)
- Discovery and Analysis of Cofactor-dependent Phosphoglycerate Mutase Homologs as Novel Phosphoserine (2012) (0)
- Diversity and Evolution of Aromatic Compounds Degrading Pseudomonads (1997) (0)
- Complete Genome Sequence of the Acetic Acid Bacterium <named-content content-type='genus-species'>Acetobacter aceti</named-content> NBRC 14818 (2020) (0)
- 1P-0218 CLAMP, SR-B1 C-terminal binding protein, regulates the SR-B1 protein expression level in the liver (2003) (0)
- Mechanism of RRR-alpha-tocopherol transport mediated by RRR-alpha-tocopherol transfer protein in liver cells (1998) (0)
- Iconographies supplémentaires de l'article : Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma (2013) (0)
- [HDL receptor family]. (2001) (0)
- 3P-009 Discovery of a protein with intermolecular disulfide bond that has a thermostability from Hydrogenobacter thermophilus TK-6 (2014) (0)
- Synthesis of Resolvin E2 (2010) (0)
- [The metabolism of glycerophospholipid and its regulation in mammalian cells]. (2011) (0)
- A novel IRE1 signaling triggered by membrane lipid saturation (2015) (0)
- EpsinR is required for the transport of the cholera toxin B-subunit from recycling endosomes to the Golgi (2016) (0)
- Search for the upstream factors of a novel MAP kinase pathway activated by either heat stress or the alterations of membrane fatty acid composition (2016) (0)
- IRE1 protects saturated fatty acid-induced lipotoxicity through XBP1-independent pathway (2016) (0)
- A new probe for phosphatidylserine (PS) sensitive to the asymmetry of PS distribution in lipid bilayers (2015) (0)
- The mechanism underlying the activation of STING variants associated with an autoimmune disease SAVI (2016) (0)
- Regulation of the high-specificity Rubisco genes by the third CbbR-type regulator in a hydrogen-oxidizing bacterium Hydrogenovibriomarinus. (2022) (0)
- The development of a new method for depletion of phosphatidylserine with phosphatidylserine decarboxylase (2017) (0)
- α-Tocopherol transfer protein and familial isolated vitamin E deficiency (2012) (0)
- Saturated phospholipids induce inflammatory response (2016) (0)
- The role of oxidized phaspholipid-derived lipid mediators in IgE-mediated mast cell activation (2016) (0)
- BR-P7 Succinate production from glycerol with acetate as an electron sink(Section IV Biorefinery) (2009) (0)
- 1SC-02 Characterization and regulation of aerobic and anaerobic respiratory enzymes of Pseudomonas aeruginosa(1SC Structural Features and Molecular Evolution of Bioenergetic Enzymes,The 49th Annual Meeting of the Biophysical Society of Japan) (2011) (0)
- 2P-0456 Supernatant protein factor (SPF), a cystosolic squalene epoxidase regulator (2003) (0)
- Research transfer protein disruption confers resistance to malarial infection in mice (2010) (0)
- [Lipid transfer proteins]. (2004) (0)
- Implication of an intracellular phospholipase A1, KIAA0725, in cycling of TGN46 by hydrolyzing phosphatidylethanolamine (2005) (0)
- Gene disruption of 2-oxoglutarate : ferredoxin oxidoreductase in Hydrogenobacter thermophilus TK-6 (2003) (0)
- Phosphorylation of ATP8A1 is essential for ATP8A1 function at recycling endosomes (2016) (0)
- RRR-alpha-tocopherol transfer protein, major determinant of plasma vitamin E level (1998) (0)
- Erratum to “Characterization of two different 2-oxoglutarate:ferredoxin oxidoreductases from Hydrogenobacter thermophilus TK-6” [Biochem. Biophys. Res. Commun. 312 (2003) 1297–1302] (2004) (0)
- Protection against saturated fatty acid-induced lipotoxicity by SREBP pathway (2016) (0)
- Functional roles of the conserved glutamate residues in nitric oxide reductase from Pseudomonas aeruginosa (2017) (0)
- [Emerging roles of intracellular phosphatidylserine (PS) in membrane traffic]. (2012) (0)
- 1P-130 Studies on the carbon and energy metabolism of the thermophilic hydrogen-oxidizing bacterium Hydrogenophilus thermoluteolus TH-1 (2015) (0)
- Cellular responses to membrane phospholipid saturation and unsaturation (2016) (0)
- Succinate production from glycerol with acetate as an electron sink (2009) (0)
- 313 Alpha-Tocopherol Transfer Protein is Expressed in First-Trimester and Term Human Placenta (2005) (0)
- [Scavenger receptor family and molecular mechanism of xenobiotic removal]. (2001) (0)
- α-Tocopherol Transfer Protein and Familial Vitamin E Deficiency (1996) (0)
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What Schools Are Affiliated With Hiroyuki Arai?
Hiroyuki Arai is affiliated with the following schools: