Hiroyuki Sasaki
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Japanese geneticist
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Genetics
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Biology
Hiroyuki Sasaki's Degrees
- Bachelors Biology University of Tokyo
- Masters Genetics University of Tokyo
- PhD Genetics University of Tokyo
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Why Is Hiroyuki Sasaki Influential?
(Suggest an Edit or Addition)According to Wikipedia, is a Japanese geneticist known for contributing to clarify epigenetic regulations during gametogenesis and embryogenesis through investigation of genomic imprinting as a model. He participates in the International Human Epigenome Consortium [IHEC].
Hiroyuki Sasaki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (2004) (1316)
- Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes (2008) (1138)
- DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. (2008) (882)
- Epigenetic events in mammalian germ-cell development: reprogramming and beyond (2008) (810)
- Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. (2006) (581)
- Targets and dynamics of promoter DNA methylation during early mouse development (2010) (561)
- Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. (2007) (505)
- Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. (2008) (448)
- Parental-origin-specific epigenetic modification of the mouse H19 gene (1993) (437)
- Derivation of Human Trophoblast Stem Cells. (2018) (417)
- Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. (2007) (395)
- Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus (2011) (359)
- Regulation of imprinted X-chromosome inactivation in mice by Tsix. (2001) (325)
- Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene. (1992) (290)
- Genomic organization of the human-amyloid beta-protein precursor gene. (1990) (282)
- The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. (2009) (280)
- Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2. (1997) (277)
- Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases (2013) (255)
- Pro----leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Sträussler syndrome. (1989) (254)
- Genomic Imprinting and Physiological Processes in Mammals (2019) (250)
- MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. (2011) (250)
- Tsix silences Xist through modification of chromatin structure. (2005) (245)
- MVH in piRNA processing and gene silencing of retrotransposons. (2010) (237)
- Synergistic Function of DNA Methyltransferases Dnmt3a and Dnmt3b in the Methylation of Oct4 and Nanog (2007) (236)
- The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development (2000) (229)
- Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method (1994) (219)
- Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes (2011) (217)
- Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells (2014) (199)
- Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS–M (1996) (197)
- De novo DNA methylation drives 5hmC accumulation in mouse zygotes (2016) (181)
- Generation of human oogonia from induced pluripotent stem cells in vitro (2018) (164)
- Temporal and spatial regulation of H19 imprinting in normal and uniparental mouse embryos. (1995) (159)
- Increased HTLV‐I proviral DNA in HTLV‐I–associated myelopathy: A quantitative polymerase chain reaction study (1991) (154)
- Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification (2007) (144)
- Complementary DNA for the mouse homolog of the human amyloid beta protein precursor. (1987) (140)
- Genome-wide profiling of promoter methylation in human (2006) (136)
- Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development (2010) (132)
- Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells (2009) (132)
- Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome (2015) (125)
- Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming (2011) (124)
- A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse (2009) (119)
- Correlation between Shh expression and DNA methylation status of the limb-specific Shh enhancer region during limb regeneration in amphibians. (2007) (118)
- An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. (2012) (115)
- In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. (2016) (112)
- Lysyl 5-Hydroxylation, a Novel Histone Modification, by Jumonji Domain Containing 6 (JMJD6)* (2013) (111)
- De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation (2004) (111)
- Diagnosis of familial amyloidotic polyneuropathy by recombinant DNA techniques. (1984) (108)
- Three novel DNMT3B mutations in Japanese patients with ICF syndrome. (2002) (103)
- Global Landscape and Regulatory Principles of DNA Methylation Reprogramming for Germ Cell Specification by Mouse Pluripotent Stem Cells. (2016) (103)
- Meiotic and epigenetic aberrations in Dnmt3L‐deficient male germ cells (2006) (102)
- Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression. (2012) (102)
- DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis (2015) (101)
- Microarray analysis of promoter methylation in lung cancers (2006) (99)
- Loss of the maternal imprint in Dnmt3Lmat-/- mice leads to a differentiation defect in the extraembryonic tissue. (2006) (97)
- Maternal high-fat diet induces insulin resistance and deterioration of pancreatic β-cell function in adult offspring with sex differences in mice. (2014) (93)
- Genetic evidence for Dnmt3a‐dependent imprinting during oocyte growth obtained by conditional knockout with Zp3‐Cre and complete exclusion of Dnmt3b by chimera formation (2010) (93)
- Bisulfite sequencing and dinucleotide content analysis of 15 imprinted mouse differentially methylated regions (DMRs): paternally methylated DMRs contain less CpGs than maternally methylated DMRs (2006) (93)
- Identification of the Imprinted KLF14 Transcription Factor Undergoing Human-Specific Accelerated Evolution (2007) (93)
- Type I familial amyloid polyneuropathy. A pathological study of the peripheral nervous system. (1990) (92)
- Corrigendum: Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome (2016) (90)
- Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos (2017) (86)
- Unusually high conservation of untranslated sequences in cDNAs for Trimeresurus flavoviridis phospholipase A2 isozymes. (1992) (84)
- Abnormal DNA Methyltransferase Expression in Mouse Germline Stem Cells Results in Spermatogenic Defects1 (2009) (79)
- Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development (2012) (79)
- In vitro expansion of mouse primordial germ cell‐like cells recapitulates an epigenetic blank slate (2017) (77)
- Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos. (2019) (77)
- Evolution of the vertebrate DNMT3 gene family: a possible link between existence of DNMT3L and genomic imprinting (2006) (76)
- Genomic imprinting and its relevance to congenital disease, infertility, molar pregnancy and induced pluripotent stem cell (2012) (76)
- Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta. (2016) (75)
- Stochastic imprinting in the progeny of Dnmt3L-/- females. (2006) (72)
- Production of recombinant human transthyretin with biological activities toward the understanding of the molecular basis of familial amyloidotic polyneuropathy (FAP). (1991) (72)
- Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. (2008) (71)
- Structure and expression of the alternatively-spliced forms of mRNA for the mouse homolog of Alzheimer's disease amyloid beta protein precursor. (1989) (69)
- Mechanism of chromosomal integration of transgenes in microinjected mouse eggs: sequence analysis of genome-transgene and transgene-transgene junctions at two loci. (1993) (66)
- Positive and negative regulatory elements for the expression of the Alzheimer's disease amyloid precursor-encoding gene in mouse. (1992) (66)
- Structure of the chromosomal gene for human serum prealbumin. (1985) (65)
- Parental methylation patterns of a transgenic locus in adult somatic tissues are imprinted during gametogenesis. (1992) (64)
- Inherited type of allelic methylation variations in a mouse chromosome region where an integrated transgene shows methylation imprinting. (1991) (61)
- Activation of an imprinted Igf 2 gene in mouse somatic cell cultures (1993) (59)
- Genomic imprinting: significance in development and diseases and the molecular mechanisms. (1996) (57)
- Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L. (2006) (56)
- Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos. (2009) (54)
- Unregulated Expression of the Imprinted Genes H19 andIgf2r in Mouse Uniparental Fetuses* (2002) (54)
- Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. (2019) (52)
- RNA sequencing-based identification of aberrant imprinting in cloned mice. (2014) (51)
- Tsix defective in splicing is competent to establish Xist silencing (2006) (49)
- CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome (2018) (49)
- Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development. (2011) (48)
- ICF syndrome in a girl with DNA hypomethylation but without detectable DNMT3B mutation (2004) (47)
- Structural and functional analysis of a 0.5-Mb chicken region orthologous to the imprinted mammalian Ascl2/Mash2-Igf2-H19 region. (2005) (46)
- Creutzfeldt‐Jakob disease patients with congophilic kuru plaques have the missense variant prion protein common to Gerstmann‐Sträussler syndrome (1990) (45)
- HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse (2014) (42)
- Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline (2018) (42)
- Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes (2017) (42)
- DNA methylation and genomic imprinting in mammals. (1993) (41)
- DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells (2014) (41)
- An evolutionarily conserved putative insulator element near the 3' boundary of the imprinted Igf2/H19 domain. (2002) (41)
- Isolation and sequencing of a cDNA clone encoding 107 kDa sialoglycoprotein in rat liver lysosomal membranes (1989) (40)
- Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non-small cell lung cancer. (2017) (39)
- Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients (2013) (39)
- Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice (2017) (39)
- A methylation imprint mark in the mouse imprinted gene Grf1/Cdc25Mm locus shares a common feature with the U2afbp-rs gene: an association with a short tandem repeat and a hypermethylated region. (1998) (39)
- Disruption of mesodermal enhancers for Igf2 in the minute mutant. (2002) (39)
- Imprinting and looping: epigenetic marks control interactions between regulatory elements. (2005) (38)
- A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip (2010) (38)
- DBTSS/DBKERO for integrated analysis of transcriptional regulation (2017) (37)
- Role of de novo DNA methyltransferases in initiation of genomic imprinting and X-chromosome inactivation. (2004) (36)
- Effect of Tsix disruption on Xist expression in male ES cells (2003) (35)
- Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy. (1986) (34)
- Haplotype analysis of familial amyloidotic polyneuropathy (1989) (34)
- Tsix-deficient X chromosome does not undergo inactivation in the embryonic lineage in males: implications for Tsix-independent silencing of Xist (2006) (33)
- Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes (2013) (33)
- Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation (2019) (33)
- Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus (2013) (32)
- De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes (2008) (32)
- Large-scale identification and mapping of nuclear matrix-attachment regions in the distal imprinted domain of mouse chromosome 7. (2004) (32)
- Allele‐specific detection of nascent transcripts by fluorescence in situ hybridization reveals temporal and culture‐induced changes in Igf2 imprinting during pre‐implantation mouse development (2001) (31)
- X‐inactivation is stably maintained in mouse embryos deficient for histone methyl transferase G9a (2004) (30)
- Human transthyretin (prealbumin) gene and molecular genetics of familial amyloidotic polyneuropathy. (1989) (29)
- The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster. (2000) (28)
- Genomic organization and promoter analysis of the Dnmt3b gene. (2003) (28)
- Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA (2018) (28)
- Cloning and sequence analysis of cDNA for Trimeresurus flavoviridis phospholipase A2, and consequent revision of the amino acid sequence. (1990) (27)
- The inheritance of germline-specific epigenetic modifications during development. (1993) (27)
- The two-domain hypothesis in Beckwith–Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster (2005) (26)
- Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2–q12.1 (1987) (26)
- Reprogramming of the histone H3.3 landscape in the early mouse embryo (2020) (25)
- Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes (2013) (25)
- Haplotype analysis of familial amyloidotic polyneuropathy. Evidence for multiple origins of the Val----Met mutation most common to the disease. (1989) (25)
- Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters (2021) (24)
- Zfp281 Shapes the Transcriptome of Trophoblast Stem Cells and Is Essential for Placental Development. (2019) (24)
- Structure of the mutant prealbumin gene responsible for familial amyloidotic polyneuropathy. (1986) (24)
- Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing (2017) (23)
- Germline genes hypomethylation and expression define a molecular signature in peripheral blood of ICF patients: implications for diagnosis and etiology (2014) (23)
- Clinical and Immunological Characterization of ICF Syndrome in Japan (2018) (22)
- Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation. (2019) (22)
- Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse (2011) (21)
- Defects in dosage compensation impact global gene regulation in the mouse trophoblast (2017) (21)
- Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers. (1997) (20)
- Active role of small non-coding RNAs derived from SINE/B1 retrotransposon during early mouse development (2012) (20)
- PRESYMPTOMATIC DIAGNOSIS OF HETEROZYGOSITY FOR FAMILIAL AMYLOIDOTIC POLYNEUROPATHY BY RECOMBINANT DNA TECHNIQUES (1985) (19)
- A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip (2010) (19)
- Imprinted genes are up-regulated by growth arrest in embryonic fibroblasts. (1997) (18)
- Nucleotide sequence of a 28-kb mouse genomic region comprising the imprinted Igf2 gene. (1996) (18)
- Amyloid beta-protein gene duplication is not common in Alzheimer's disease: analysis by polymorphic restriction fragments. (1988) (18)
- Isolation and sequencing of a cDNA clone encoding 96 kDa sialoglycoprotein in rat liver lysosomal membranes. (1989) (18)
- A 210-kb segment of tandem repeats and retroelements located between imprinted subdomains of mouse distal chromosome 7. (2004) (17)
- Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human. (2000) (17)
- Analysis of small RNA profiles during development. (2007) (16)
- Tetramer formation of a variant type human transthyretin (prealbumin) produced by Escherichia coli expression system. (1989) (16)
- Expression of Alzheimer amyloid beta-protein precursor gene in neuronal cells. (1991) (16)
- Whole-Mount MeFISH: A Novel Technique for Simultaneous Visualization of Specific DNA Methylation and Protein/RNA Expression (2014) (15)
- Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability (2017) (14)
- Sequence of a 42-kb mouse region containing the imprinted H19 locus: identification of a novel muscle-specific transcription unit showing biallelic expression (1998) (14)
- Molecular analysis of a variant type of familial amyloidotic polyneuropathy showing cerebellar ataxia and pyramidal tract signs. (1987) (13)
- CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats (2020) (12)
- Biochemical and genetic characterization of type I familial amyloidotic polyneuropathy (1987) (12)
- Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice (2018) (12)
- Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites (2017) (11)
- Genetic and clinical studies of Japanese patients with familial amyloid polyneuropathy. (1989) (10)
- De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. (2008) (10)
- Activity of a metallothionein-transthyretin fusion gene in transgenic mice. Possible effect of plasmid sequences on tissue-specific expression. (1989) (9)
- Differential chromatin packaging of genomic imprinted regions between expressed and non-expressed alleles. (2000) (8)
- The 5′ region of Xist RNA has the potential to associate with chromatin through the A-repeat (2017) (7)
- Stochastic imprinting in the progeny of Dnmt3L 2 / 2 females (2006) (7)
- A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation (2020) (7)
- The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes (2021) (7)
- Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo (2020) (7)
- Genetic analysis of familial amyloidotic polyneuropathy, an autosomal dominant disease. (1989) (6)
- TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication. (2021) (6)
- Identification of SLC38A7 as a Prognostic Marker and Potential Therapeutic Target of Lung Squamous Cell Carcinoma (2021) (5)
- A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-of-origin effects (2015) (5)
- Enhancer-dependent, locus-wide regulation of the imprinted mouse insulin-like growth factor II gene. (1998) (5)
- Genomic organization of the human amyloid beta-protein precursor gene. (1990) (5)
- Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells. (2020) (5)
- Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring (2019) (4)
- Clinical features and diagnosis by recombinant DNA techniques of familial amyloid polyneuropathy in Japan. (1989) (3)
- Localization of mouse imprinted gene U2af1-rs1 to A3.2-4 band of chromosome 11 by FISH. (1994) (3)
- [Familial amyloid polyneuropathy (FAP), in an inborn habitat of Hiroshima Prefecture, Japan]. (1986) (3)
- A HindIII polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease. (1987) (3)
- Germ line-specific programming of parental genomes for development (1993) (2)
- Assessement of Structure and Binding Capacities of Secreted Mutant Transthyretins by an E. Coli System (1991) (2)
- Structural and functional analysis of a 0 . 5-Mb chicken region orthologous to the imprinted mammalian Ascl 2 / Mash 2 – Igf 2 – H 19 region (2004) (2)
- Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes (2022) (2)
- Ddhd1 knockout mouse as a model of locomotive and physiological abnormality in familial spastic paraplegia (2021) (2)
- Neuraminidase Amino Acid Sequences of Influenza A/H3N2 and B Viruses Isolated from Influenza Patients in the 2014/15 Japanese Influenza Season. (2016) (2)
- Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation (2019) (2)
- [Analysis of the Neuraminidase Amino Acid Sequences of Influenza A/H1N1pdm09, A/H3N2, and B Viruses Isolated from Influenza Patients in the 2013/14 Japanese Influenza Season]. (2015) (2)
- “Sporadic” prealbumin-related amyloid polyneuropathy: report of two cases (2004) (2)
- Maternal DNMT3A-dependent de novo methylation of the zygotic paternal genome inhibits gene expression in the early embryo (2020) (1)
- The UHRF protein family in epigenetics, development, and carcinogenesis (2022) (1)
- Structure and expression of Alzheimer's amyloid β-protein precursor gene (1990) (1)
- Characterization of genetic‐origin‐dependent monoallelic expression in mouse embryonic stem cells (2019) (1)
- Diagnosis of Familial Amyloid Polyneuropathy by Recombinant DNA Techniques in Relation with Clinical Features (1988) (1)
- [Establishment of genomic imprints in the mammalian germline and their maintenance in preimplantation embryos]. (2007) (1)
- Sequences in the H19 ICR that are transcribed as small RNA in oocytes are dispensable for methylation imprinting in YAC transgenic mice. (2012) (1)
- [DNA diagnosis of familial amyloidotic polyneuropathy]. (1985) (1)
- Parental imprinting and epigenetic programming of the mouse genome: long lasting consequences for development and phenotype (1993) (1)
- Biochemical and Genetic Characterization of a Variant Transthyretin Causing Familial Amyloidotic Polyneuropathy (1986) (1)
- DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis (2015) (1)
- Identification of Genomic Alterations Acquired During Treatment With EGFR-TKIs in Non-small Cell Lung Cancer (2019) (1)
- Localization of mouse imprinted gene U2af1-rs1 to A3.2-4 band of Chromosome 11 by FISH (2004) (1)
- Supplemental Information In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells (2016) (0)
- Molecular Cloning and Structural Analysis of the Human Amyloid ß Protein Precursor Gene (1990) (0)
- DNA Methylation-Dependent and -Independent Regulation of Monoallelic Expression by Zfp57 in Ground-State Embryonic Stem Cells (2016) (0)
- Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites (2017) (0)
- DNA Polymorphisms Analysis in Families with Familial Amyloidotic Polyneuropathy (FAP) from Different Ethnic Origins (1988) (0)
- Supplemental Information Derivation of Human Trophoblast Stem Cells (2017) (0)
- Functional analysis of the PWWP domain (a H3K36me3 reader) of Dnmt3a in DNA methylation establishment in mouse oocytes and somatic cells (2017) (0)
- Role for SmcHD1 in the establishment of the proper epigenetic states of the inactive X chromosome (2017) (0)
- Promoter Methylation Patterns in Human Genome: Implication for Clinical Epigenomic Studies (2008) (0)
- Role of H3K9 methyltransferase G9a during oogenesis and early embryo development (2016) (0)
- Active role of small non-coding RNAs derived from SINE/B1 retrotransposon during early mouse development (2011) (0)
- Reprogramming of the histone H3.3 landscape in the early mouse embryo (2020) (0)
- Title Roles of MIWI , MILI and PLD 6 in small RNA regulation inmouse growing oocytes (2017) (0)
- Long-term influence of maternal diabetes on the phenotype and gene expression of the offspring in adulthood (2016) (0)
- DNA methylation in epigenetics, development, and imprinting (2005) (0)
- A search for genomic regions associated with neurodevelopmental differences between Rett syndrome monozygotic twins by genomic and epigenomic comparative assays (2009) (0)
- Identification of ZBTB24 protein domains and motifs essential for heterochromatin localization and transcriptional gene activation (2019) (0)
- Mutations in PLD6 and MILI in mouse oocytes reveal sex-dependent differences in piRNA regulation (2016) (0)
- A Recombinants System for Production of Variant Type Human Transthyretin(TTR) (1991) (0)
- Toward Establishment of an Animal Model for Familial Amyloidotic Polyneuropathy: Generation and Characterization of Transgenic Mice (1988) (0)
- Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA (2018) (0)
- Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing (2017) (0)
- Essential role of Uhrf1 during oocyte growth and preimplantation development (2016) (0)
- Genomic imprinting : single topic volume ; 33 tables (2006) (0)
- Defect of DNA repair pathway is involved in pathogenesis of ICF syndrome (2017) (0)
- The mouse l23mrp gene located downstream of the imprinted ins2/igf2/h19 region is biallelically expressed and not influenced by the h19 enhancer (1997) (0)
- Additional file 2: Table S1. of Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites (2017) (0)
- Haplotype Analisis of Familial Amyloidotic Polyneuropathy: an Evidence for Multiple Origins of the Val→met Mutation (1988) (0)
- Genomic Imprinting: Mechanisms, Significance and Evolution (2003) (0)
- Structure and Expression of mRNA for the Mouse Homolog of Alzheimer Amyloid Beta Protein Precursor (1990) (0)
- Quantitative dynamics of epigenome remodeling in the primordial germ cell formation (2017) (0)
- H3K9 methyltransferase G9a regulates oogenesis and early embryo development (2017) (0)
- Incomplete reprogramming of germline DNA methylation in the human placenta (2016) (0)
- Low Input Genome-Wide DNA Methylation Analysis with Minimal Library Amplification. (2022) (0)
- Transcriptional Regulation of Monoallelically Expressed Genes in Ground-state Embryonic Stem Cells (2017) (0)
- 2011/12及び2012/13年インフルエンザ流行期に患者より分離されたA/H3N2型ウイルス96株のNA遺伝子配列と薬剤感受性との関連についての検討 (2015) (0)
- 2014/15年流行期に患者より分離されたインフルエンザA/H3N2,Bウイルスのノイラミニダーゼ遺伝子と薬剤感受性との関連についての検討 (2016) (0)
- Elucidation of the role of ADD domain of Dnmt3a for DNA methylation establishment in mouse oocytes (2017) (0)
- A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns (2021) (0)
- CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers (2022) (0)
- The ADD domain of Dnmt3a is important for DNA methylation establishment in mouse oocytes (2019) (0)
- SCML2 establishes germline epigenome during spermatogenesis (2016) (0)
- CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers (2022) (0)
- Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome with distinctive genome-wide DNA hypomethylation. (2022) (0)
- Forward genetic screen using haploid embryonic stem cells identifies a regulator for extraembryonic development (2017) (0)
- Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring (2019) (0)
- A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns (2021) (0)
- [Analysis of influenza A/H3N2 neuraminidase genes obtained from influenza patients in the 2011/12 and 2012/13 seasons in Japan]. (2015) (0)
- 3D chromosome relaxation with TE-rich heterochromatin opening during de novo DNA methylation in gonocyte (2018) (0)
- O-16. Comparative chromosome study between chicken and Guinea fowl by FISH(Abstracts of the 52nd Annual Meeting of the Society of Chromosome Research) (2001) (0)
- New function of cytoplasmic Uhrf1 during oogenesis and early embryogenesis (2017) (0)
- [Parental imprinting of mammalian genomes]. (1992) (0)
- O13. Genomic imprinting and small RNAs in mammalian germ cells (2010) (0)
- Dissection of Structure-Function Relationship of ZBTB24 and Molecular Pathology of ICF Syndrome (2017) (0)
- Does mtDNA epigenetics exist? 〜 an investigation of DNA methylation in mammalian mitochondria (2016) (0)
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Hiroyuki Sasaki is affiliated with the following schools: