Hitoshi Endou
#129,889
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Hitoshi Endou's AcademicInfluence.com Rankings
Hitoshi Endoumedical Degrees
Medical
#2141
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#2543
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Pharmacology
#222
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#262
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Hitoshi Endou's Degrees
- PhD Pharmacology University of Tokyo
- Masters Pharmacology University of Tokyo
- Bachelors Pharmacy University of Tokyo
Why Is Hitoshi Endou Influential?
(Suggest an Edit or Addition)Hitoshi Endou's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular identification of a renal urate–anion exchanger that regulates blood urate levels (2002) (1280)
- Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)* (1998) (968)
- CATs and HATs: the SLC7 family of amino acid transporters (2004) (682)
- Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. (2001) (645)
- Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter* (1997) (636)
- The SLC22 drug transporter family (2004) (504)
- Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. (2001) (495)
- Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter* (1996) (494)
- Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain* (1999) (483)
- Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity* (1999) (480)
- Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta* (2000) (394)
- Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. (2002) (373)
- Identification of multispecific organic anion transporter 2 expressed predominantly in the liver (1998) (347)
- Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. (2004) (343)
- Identification and characterization of the high-affinity choline transporter (2000) (330)
- The multispecific organic anion transporter (OAT) family (2000) (321)
- Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans* (2008) (319)
- Molecular physiology of urate transport. (2005) (315)
- Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. (2002) (279)
- Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (272)
- Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity. (2002) (271)
- Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities (1999) (261)
- Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids* (2000) (256)
- Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters (2002) (249)
- L‐type amino acid transporter 1 as a potential molecular target in human astrocytic tumors (2006) (235)
- Expression Cloning of a Na+-independent Aromatic Amino Acid Transporter with Structural Similarity to H+/Monocarboxylate Transporters* (2001) (233)
- Molecular physiology of renal organic anion transporters. (2006) (229)
- T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. (1999) (227)
- Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney. (2002) (226)
- Identification of a Novel System L Amino Acid Transporter Structurally Distinct from Heterodimeric Amino Acid Transporters* (2003) (225)
- Uric Acid Causes Vascular Smooth Muscle Cell Proliferation by Entering Cells via a Functional Urate Transporter (2005) (222)
- L‐type amino‐acid transporter 1 as a novel biomarker for high‐grade malignancy in prostate cancer (2009) (218)
- Characterization of uremic toxin transport by organic anion transporters in the kidney. (2004) (218)
- l‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth (2010) (211)
- Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. (2004) (204)
- Organic anion transporter family: current knowledge. (2006) (203)
- Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I–III nonsmall cell lung cancer (2008) (198)
- Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. (2002) (186)
- Interactions of Human Organic Anion Transporters and Human Organic Cation Transporters with Nonsteroidal Anti-Inflammatory Drugs (2002) (185)
- Molecular Identification of a Novel Carnitine Transporter Specific to Human Testis (2002) (184)
- New insights into renal transport of urate (2007) (183)
- Interactions of Human Organic Anion Transporters with Diuretics (2004) (181)
- The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus* (2004) (179)
- Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier (2001) (179)
- Identification of an Amino Acid Transporter Associated with the Cystinuria-related Type II Membrane Glycoprotein* (1999) (178)
- Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. (2004) (168)
- Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease (2005) (168)
- Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney. (1999) (167)
- A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters (2005) (166)
- Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. (1999) (164)
- Intrarenal handling of proteins in rats using fractional micropuncture technique. (1992) (157)
- Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. (2001) (154)
- Function and localization of urate transporter 1 in mouse kidney. (2004) (150)
- Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. (2002) (149)
- Role of human organic anion transporter 4 in the transport of ochratoxin A. (2002) (148)
- Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. (2001) (148)
- Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. (2002) (144)
- Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats (2001) (143)
- Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. (2002) (142)
- Expression of a system L neutral amino acid transporter at the blood–brain barrier (2000) (141)
- l‐type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms (2008) (141)
- Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. (2002) (134)
- The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. (1999) (131)
- Substrate specificity to maintain cellular ATP along the mouse nephron. (1988) (130)
- Human Sodium Phosphate Transporter 4 (hNPT4/SLC17A3) as a Common Renal Secretory Pathway for Drugs and Urate* (2010) (130)
- Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis (2006) (130)
- The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. (2002) (130)
- Human vascular smooth muscle cells express a urate transporter. (2006) (129)
- Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. (2000) (123)
- LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells (2013) (122)
- Urate transport via human PAH transporter hOAT1 and its gene structure. (2003) (120)
- Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. (2001) (119)
- Novel nonsense mutation in the Na+/HCO3- cotransporter gene (SLC4A4) in a patient with permanent isolated proximal renal tubular acidosis and bilateral glaucoma. (2001) (117)
- BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. (2008) (116)
- Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth. (2016) (116)
- Interaction of human organic anion transporters with various cephalosporin antibiotics. (2002) (114)
- Identification of a Novel Voltage-driven Organic Anion Transporter Present at Apical Membrane of Renal Proximal Tubule* (2003) (113)
- Characterization of ochratoxin A transport by human organic anion transporters. (2001) (112)
- Transport of 3-Fluoro-l-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET (2012) (112)
- Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports d-serine with high affinity (2000) (111)
- High expression of L‐type amino‐acid transporter 1 (LAT1) in gastric carcinomas: Comparison with non‐cancerous lesions (2011) (110)
- Novel liver‐specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate (2007) (108)
- A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese. (2004) (107)
- Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine. (1998) (106)
- Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. (2005) (105)
- Fluorine-18-α-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer: A Clinicopathologic Study (2007) (104)
- Transport of ochratoxin A by renal multispecific organic anion transporter 1. (1998) (104)
- The multispecific organic anion transporter family: properties and pharmacological significance. (2004) (103)
- Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites. (2003) (98)
- Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. (1999) (98)
- Contribution of Organic Anion Transporters to the Renal Uptake of Anionic Compounds and Nucleoside Derivatives in Rat (2003) (98)
- The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5) (2018) (98)
- Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. (2002) (96)
- Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors. (2004) (91)
- Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. (2001) (91)
- L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia (2014) (90)
- Human organic anion transporters mediate the transport of tetracycline. (2002) (88)
- Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (88)
- Interactions of urate transporter URAT1 in human kidney with uricosuric drugs (2011) (86)
- Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. (2003) (85)
- Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules (2005) (84)
- Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. (2001) (82)
- Transient upregulation of the glial glutamate transporter GLAST in response to fibroblast growth factor, insulin-like growth factor and epidermal growth factor in cultured astrocytes. (2001) (81)
- Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (81)
- Interactions of human organic anion as well as cation transporters with indoxyl sulfate. (2003) (81)
- Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc (2019) (80)
- Quantitative Evaluation of the Drug-Drug Interactions between Methotrexate and Nonsteroidal Anti-Inflammatory Drugs in the Renal Uptake Process Based on the Contribution of Organic Anion Transporters and Reduced Folate Carrier (2004) (79)
- Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions. (2004) (78)
- Differential gene expression of organic anion transporters in male and female rats. (2002) (78)
- Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity. (2003) (78)
- The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia (2004) (78)
- System l-amino acid transporters are differently expressed in rat astrocyte and C6 glioma cells (2004) (77)
- The genetic polymorphism of drug transporters: functional analysis approaches. (2004) (77)
- Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract (2007) (75)
- Identification of a Novel Na+-independent Acidic Amino Acid Transporter with Structural Similarity to the Member of a Heterodimeric Amino Acid Transporter Family Associated with Unknown Heavy Chains* (2002) (73)
- Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid. (2008) (72)
- Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation. (2001) (72)
- Cadmium transport by human Nramp 2 expressed in Xenopus laevis oocytes. (2003) (71)
- Hydrogen Peroxide Induces Necrosis, Apoptosis, Oncosis and Apoptotic Oncosis of Mouse Terminal Proximal Straight Tubule Cells (1999) (71)
- Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. (2004) (70)
- Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. (2001) (69)
- Localization of 25-hydroxyvitamin D3-lα-hydroxylase activity in the mammalian kidney (1980) (69)
- High affinity d- and l-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices (2004) (68)
- Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3). (2000) (68)
- Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters. (2008) (68)
- Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. (2004) (67)
- Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. (2002) (67)
- Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout (2009) (67)
- Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells. (2008) (66)
- Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas. (2003) (66)
- High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas (2012) (66)
- A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout. (2005) (65)
- c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells. (2012) (63)
- Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis (2011) (62)
- Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis (2004) (62)
- Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung. (2008) (62)
- Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. (2002) (61)
- Effect of fenofibrate on uric acid metabolism and urate transporter 1. (2010) (61)
- Two male siblings with hereditary renal hypouricemia and exercise-induced ARF. (2003) (61)
- Renal urate handling: Clinical relevance of recent advances (2005) (59)
- Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney. (2000) (59)
- The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. (2004) (58)
- Pathogenesis of adult-onset type II citrullinemia caused by deficiency of citrin, a mitochondrial solute carrier protein: tissue and subcellular localization of citrin. (2001) (58)
- Correlation of angiogenesis with 18F‐FMT and 18F‐FDG uptake in non‐small cell lung cancer (2009) (58)
- Cisplatin-induced toxicity in immortalized renal cell lines established from transgenic mice harboring temperature sensitive SV40 large T-antigen gene (1996) (57)
- Molecular Mechanism of Ochratoxin A Transport in the Kidney (2010) (56)
- L‐type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non‐small cell lung cancer (2009) (56)
- Furosemide directly stimulates prostaglandin E2 production in the thick ascending limb of Henle's loop. (1989) (55)
- JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells. (2014) (54)
- Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3. (2006) (54)
- Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction (2006) (54)
- Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction. (2005) (54)
- Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia. (2005) (53)
- Metabolism and pharmacokinetic studies of JPH203, an L-amino acid transporter 1 (LAT1) selective compound. (2012) (53)
- Involvement of H2O2 production in cisplatin-induced nephrotoxicity. (1998) (52)
- Cytochrome P-450 monooxygenase system in the rabbit kidney: its intranephron localization and its induction. (1983) (52)
- Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions. (2004) (51)
- Prognostic significance of L‐type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung (2009) (50)
- Association between GLUT9 and gout in Japanese men (2010) (50)
- Altered renal elimination of organic anions in rats with chronic renal failure. (2005) (50)
- Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. (2004) (49)
- P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2. (1998) (49)
- LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung (2006) (48)
- Nephrotoxicity assessment by measuring cellular ATP content. I. Substrate specificities in the maintenance of ATP content in isolated rat nephron segments. (1989) (46)
- Functional analysis of human organic cation transporter OCT3 (SLC22A3) polymorphisms. (2010) (46)
- The RNA interference of amino acid transporter LAT1 inhibits the growth of KB human oral cancer cells. (2006) (46)
- Interactions of organic anion transporters and organic cation transporters with mycotoxins. (2008) (45)
- First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors (2020) (45)
- Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule (2005) (44)
- Integrated physiology of proximal tubular organic anion transport (2005) (44)
- Developing potent human uric acid transporter 1 (hURAT1) inhibitors. (2011) (44)
- Elimination of Organic Anions in Response to an Early Stage of Renal Ischemia-Reperfusion in the Rat: Role of Basolateral Plasma Membrane Transporters and Cortical Renal Blood Flow (2007) (44)
- Inhibition of l-type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment (2017) (43)
- Distribution of gamma-glutamyl transpeptidase and glutaminase isoenzymes in the rabbit single nephron. (1982) (43)
- Cisplatin-induced apoptosis of immortalized mouse proximal tubule cells is mediated by interleukin-1β converting enzyme (ICE) family of proteases but inhibited by overexpression of Bcl-2 (1997) (43)
- Urate transporters: an evolving field. (2011) (42)
- Evaluation of thoracic tumors with 18F‐FMT and 18F‐FDG PET‐CT: A clinicopathological study (2009) (42)
- Human cystinuria-related transporter: localization and functional characterization. (2001) (42)
- Nephrotoxicity assessment by measuring cellular ATP content. II. Intranephron site of ochratoxin A nephrotoxicity. (1989) (41)
- Protein characterization of NA+-independent system L amino acid transporter 3 in mice: a potential role in supply of branched-chain amino acids under nutrient starvation. (2007) (41)
- Nephron heterogeneity: gluconeogenesis from pyruvate in rabbit nephron (1980) (40)
- L‐type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas (2009) (40)
- The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. (2006) (39)
- Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B. (2004) (39)
- A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules* (2010) (38)
- Lipid peroxidation in isolated rat nephron segments. (1992) (37)
- An adenosine deaminase inhibitor prevents puromycin aminonucleoside nephrotoxicity. (1997) (37)
- A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter. (2006) (37)
- Urate Transport Across the Apical Membrane of Renal Proximal Tubules (2008) (37)
- Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells. (2005) (37)
- Oxidative stress and chronic allograft nephropathy. (2004) (36)
- Involvement of Multiple Transporters in the Efflux of 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors across the Blood-Brain Barrier (2004) (36)
- Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs. (2004) (36)
- Purinoceptor-mediated calcium mobilization and cellular proliferation in cultured bovine corneal endothelial cells. (2000) (34)
- Functional and Immunochemical Characterization of a Novel Organic Anion Transporter Oat8 (Slc22a9) in Rat Renal Collecting Duct (2008) (34)
- Interactions of human organic anion transporters with aristolochic acids. (2010) (32)
- Effects of in Utero Exposure to Di(n-butyl) Phthalate for Estrogen Receptors α, β, and Androgen Receptor of Leydig Cell on Rats (2014) (32)
- High expression of L-type amino acid transporter 1 as a prognostic marker in bile duct adenocarcinomas (2014) (32)
- Effect of P2Y-purinoceptor stimulation on renal gluconeogenesis in rats. (1995) (31)
- Nephrin and podocin expression around the onset of puromycin aminonucleoside nephrosis. (2005) (31)
- Intranephron distribution of cysteine S -conjugate β-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats (1997) (31)
- Hydrogen peroxide downregulates human organic anion transporters in the basolateral membrane of the proximal tubule. (2000) (30)
- Characterization of 3-[125I]iodo-alpha-methyl-L-tyrosine transport via human L-type amino acid transporter 1. (2003) (29)
- Expression and functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells. (2004) (29)
- Mouse organic anion transporter 2 (mOat2) mediates the transport of short chain fatty acid propionate. (2008) (28)
- Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. (2007) (28)
- Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride (2009) (28)
- Apical Voltage-Driven Urate Efflux Transporter NPT4 in Renal Proximal Tubule (2011) (28)
- Recent advances in molecular mechanisms of nephrotoxicity. (1998) (28)
- LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells. (2016) (28)
- Isoform selectivity of 3-125I-iodo-alpha-methyl-L-tyrosine membrane transport in human L-type amino acid transporters. (2003) (28)
- Unique and selective expression of L-amino acid transporter 1 in human tissue as well as being an aspect of oncofetal protein. (2014) (27)
- Glucose dehydrogenase (hexose 6-phosphate dehydrogenase) and the microsomal electron transport system. Evidence supporting their possible functional relationship. (1979) (27)
- Biosynthesis of Guanidinoacetic Acid in Isolated Renal Tubules (1992) (26)
- Children's toxicology from bench to bed--Drug-induced renal injury (3): Drug transporters and toxic nephropathy in childhood. (2009) (26)
- Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation (2020) (26)
- Distinct interleukin-1β-converting enzyme family proteases mediate cisplatin- and staurosporine-induced apoptosis of mouse proximal tubule cells (1998) (26)
- Oat5 and NaDC1 Protein Abundance in Kidney and Urine After Renal Ischemic Reperfusion Injury (2009) (26)
- Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells. (2006) (26)
- Inhibition of L-type amino acid transporter modulates the expression of cell cycle regulatory factors in KB oral cancer cells. (2010) (26)
- Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3. (2004) (26)
- Cisplatin-induced alterations in renal structure, ammoniagenesis and gluconeogenesis of rats. (1992) (26)
- Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney. (2003) (26)
- Expression of L-type amino acid transporter 1 in a rat model of liver metastasis: positive correlation with tumor size. (2001) (26)
- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells (2017) (25)
- Intra- and inter-nephron heterogeneity of ammoniagenesis in rats: effects of chronic metabolic acidosis and potassium depletion (1986) (25)
- A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter. (2009) (25)
- Involvement of rBAT in Na(+)-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA. (2000) (24)
- Inhibition of the amino‐acid transporter LAT1 demonstrates anti‐neoplastic activity in medulloblastoma (2019) (24)
- P 2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P 2 Y 1 and P 2 Y 2 (1998) (23)
- Human urate transporter 1 (hURAT1) mediates the transport of orotate (2011) (22)
- Atypical Leydig Cell Hyperplasia in Adult Rats with Low T and High LH Induced by Prenatal Di(n-butyl) Phthalate Exposure (2013) (22)
- Inhibitory effect of cyclic AMP on phorbol ester-stimulated production of reactive oxygen metabolites in rat glomeruli. (1989) (22)
- Biphasic increasing effect of angiotensin-II on intracellular free calcium in isolated rat early proximal tubule. (1989) (22)
- Renal Solute Transporters and Their Relevance to Serum Urate Disorder (2010) (22)
- Intracellular pH regulatory mechanism in a human renal proximal cell line (HKC-8): evidence for Na+/H+ exchanger, Cl–/HCO3– exchanger and Na+-HCO3– cotransporter (2000) (22)
- FUNCTIONAL INVOLVEMENT OF RAT ORGANIC ANION TRANSPORTER 2 (SLC22A7) IN THE HEPATIC UPTAKE OF THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG KETOPROFEN (2005) (21)
- Metformin enhances anti-tumor effect of L-type amino acid transporter 1 (LAT1) inhibitor. (2016) (21)
- Interactions of Stevioside and Steviol with Renal Organic Anion Transporters in S2 Cells and Mouse Renal Cortical Slices (2005) (21)
- Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo. (2010) (21)
- L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa. (2007) (21)
- Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway. (2007) (21)
- Drug discovery for hyperuricemia (2007) (21)
- Intranephron distribution of glycine-amidinotransferase activity in rats. (1992) (20)
- Rapid Elimination of Cefaclor from the Cerebrospinal Fluid Is Mediated by a Benzylpenicillin-Sensitive Mechanism Distinct from Organic Anion Transporter 3 (2005) (20)
- L-amino acid transporter 1 may be a prognostic marker for local progression of prostatic cancer under expectant management. (2015) (20)
- L-Type amino acid transporter 1 (LAT1) expression in lymph node metastasis of gastric carcinoma: Its correlation with size of metastatic lesion and Ki-67 labeling. (2015) (20)
- Distribution and some characteristics of cytochrome P-450 in the kidney. (1983) (20)
- Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene. (2006) (19)
- [Evaluation of nephrotoxic site in rat proximal tubule: intrarenal distributions of three enzymes and effects of mercuric chloride and gentamicin on their excretion into urine (author's transl)]. (1980) (19)
- Identification of a Novel Organic Anion Transporter Mediating Carnitine Transport in Mouse Liver and Kidney (2010) (19)
- Effect of chronic metabolic acidosis on ammonia production fromL-glutamine in microdissected rat nephron segments (1985) (19)
- Cisplatin-induced apoptosis in mouse proximal tubular cell line. (1996) (19)
- Male Sprague-Dawley Rats Exposed to In Utero Di(n-butyl) Phthalate (2013) (19)
- Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus. (2004) (18)
- Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters. (2004) (18)
- Renal drug transporters and nephrotoxicity (2006) (17)
- Nicergoline enhances glutamate uptake via glutamate transporters in rat cortical synaptosomes. (2004) (17)
- Spermatogenesis in aged rats after prenatal 3,3',4,4',5-pentachlorobiphenyl exposure. (2007) (16)
- Involvement of macromolecule synthesis, endonuclease activation and c-fos expression in cisplatin-induced apoptosis of mouse proximal tubule cells. (1998) (16)
- ATP‐induced calcium mobilization in glomerular mesangial cells is mediated by P2U purinoceptor (1996) (16)
- Mercury chloride as a possible phospholipase C activator: effect on angiotensin II-induced [Ca++]i transient in the rat early proximal tubule. (1990) (16)
- [Human renal urate transpoter URAT1 mediates the transport of salicylate]. (2010) (16)
- Amino acid transporters: molecular structure and physiological roles. (2000) (16)
- CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl. (2005) (16)
- Intranephron heterogeneity of ammoniagenesis and gluconeogenesis in rats. (1985) (15)
- Solute Transport, Energy Consumption, and Production in the Kidney (2013) (15)
- Investigation of the role of transporters on the hepatic elimination of an LAT1 selective inhibitor JPH203. (2013) (15)
- Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (15)
- First-in-human phaseIstudy of JPH203 in patients with advanced solid tumors. (2018) (14)
- Establishment of vasopressin-responsive early proximal tubular cell lines derived from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. (1995) (14)
- Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. (2010) (14)
- Sex-associated difference in estrogen receptor β expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats. (2011) (14)
- Cell type-specific activation of metabolism reveals that β-cell secretion suppresses glucagon release from α-cells in rat pancreatic islets (2006) (13)
- A novel vasopressin receptor in rat early proximal tubule. (1991) (13)
- Hyperoxia inhibits nitric oxide treatment effects in alveolar epithelial cells via effects on L-type amino acid transporter-1. (2014) (13)
- Localization of kallikrein-like activity along a single nephron in rabbits (2004) (13)
- Evaluation of nephrotoxicity using isolated nephron segments. (1986) (12)
- Relationship between chronic treatment with morphine and sex-dependent low molecular weight protein excretion. (1981) (12)
- Isolation by monoclonal antibody of intercalated cells of rabbit kidney. (1988) (12)
- Effect of adenosine on phorbol myristate acetate induced-reactive oxygen metabolite production in cultured mesangial cells. (1996) (12)
- Gene expression profiles in t24 human bladder carcinoma cells by inhibiting an l-type amino acid transporter, lat1 (2007) (11)
- Biomarker Analyses in Patients With Advanced Solid Tumors Treated With the LAT1 Inhibitor JPH203 (2020) (11)
- LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cells. (2014) (11)
- Expression and Functional Characterization of Rat Organic Anion Transporter 3 ( rOat 3 ) in the Choroid Plexus (2002) (11)
- LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation (2020) (11)
- HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency (2016) (11)
- Potent human uric acid transporter 1 inhibitors: in vitro and in vivo metabolism and pharmacokinetic studies (2012) (11)
- Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms. (2011) (11)
- Atrial natriuretic peptides stimulate renal gluconeogenesis. (1985) (11)
- Suppressive effect of dipyridamole on the proteinuria of aminonucleoside nephrosis in rat. (1979) (10)
- Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder. (1990) (10)
- Kinetic studies on microsomal glucose dehydrogenase in rat liver. (1975) (10)
- Furosemide acts on short loop of descending thin limb, but not on long loop. (1990) (10)
- A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A. (2011) (10)
- Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells. (2008) (10)
- Distributional Patterns of Phospholipase C Isozymes in Rat Kidney (1998) (9)
- Intranephron distribution of purine-metabolizing enzymes in rats. (1989) (9)
- Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor (2020) (9)
- L-type Amino Acid Transporter 1 Expression Increases in Well-Differentiated but Decreases in Poorly Differentiated Endometrial Endometrioid Adenocarcinoma and Shows an Inverse Correlation With p53 Expression (2014) (9)
- Different sensitivity to nephrotoxic agents and osmotic stress in proximal tubular and collecting duct cell lines derived from transgenic mice. (2002) (9)
- JPH 203 , an L-Type Amino Acid Transporter 1 – Selective Compound , Induces Apoptosis of YD-38 Human Oral Cancer Cells (2014) (8)
- Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. (1983) (8)
- [Arachidonic acid metabolites in the kidney]. (1990) (8)
- First-in-human phase I study of JPH203, L-type amino acids transporter 1 inhibitor, in patients with advanced solid tumors. (2018) (8)
- Quantitative analysis of electrophoretically separated proteins using Coomassie blue. (1978) (8)
- Sequential increases in 4F2hc expression during DMBA-induced hamster buccal pouch carcinogenesis. (2003) (8)
- Human Uric Acid Transporter 1 (hURAT1): An Inhibitor Structure–Activity Relationship (SAR) Study (2011) (7)
- Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats. (2002) (7)
- Ammonia production in cell lines established from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. (1994) (7)
- Intranephron PGE2 production in stroke-prone spontaneously hypertensive rats. (1990) (7)
- Time Course of Expression of 7,12-Dimethylbenz[a]anthracene-induced CYP1A1 and CYP1B1 mRNA and Protein in Rat Liver (2003) (7)
- Alterations of gluconeogenesis by ischemic renal injury in rats. (1992) (7)
- Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate (2013) (6)
- Distribution and possible functions of gamma-glutamyl-transpeptidase in the kidney. (1981) (6)
- 1 A novel transporter of SLC 22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules (2010) (6)
- Localization and properties of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in the rat kidney (1985) (6)
- Testicular Toxicology of Pubescent and Adult Rats Prenatally Exposure to 3,3',4,4',5-Pentachlorobiphenyl (2007) (6)
- Measurement of glutamate uptake and reversed transport by rat synaptosome transporters. (2004) (6)
- Epidermal growth factor in the mouse kidney: developmental changes and intranephron localizations (2004) (6)
- Molecular biology of multispecific organic anion transporter family (OAT family) (1999) (6)
- Drug Transport in the Kidney (2014) (6)
- L-type amino acid transporter 1 (LAT1)-specific inhibitor is effective against T cell-mediated nasal hyperresponsiveness. (2020) (5)
- Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells (2018) (5)
- Evidence that alpha-1-adrenergic stimuli specifically increase gluconeogenesis of the isolated proximal convoluted tubule in the rat. (1986) (5)
- Positive correlation of expression of L-type amino-acid transporter 1 with colorectal tumor progression and prognosis: Higher expression in sporadic colorectal tumors compared with ulcerative colitis-associated neoplasia. (2020) (5)
- Distinct interleukin-1beta-converting enzyme family proteases mediate cisplatin- and staurosporine-induced apoptosis of mouse proximal tubule cells. (1998) (5)
- Differential effects of DNA tumor virus genes on the expression profiles, differentiation, and morphogenetic reprogramming potential of epithelial cells. (2002) (5)
- Heterogeneity of Nephron Energy Metabolism: Implications for Response to Hypoxic Insult (1991) (5)
- Developing selective L-Amino Acid Transport 1 (LAT1) inhibitors: A Structure-Activity Relationship overview (2019) (5)
- The Acute Encephalopathy Induced by Intake of Sugihiratake Mushroom in the Patients with Renal Damage Might Be Associated with the Intoxication of Cyanide and Thiocyanate (2015) (5)
- Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (5)
- [Amino acid transporter molecule as a drug target]. (1999) (5)
- Localization of 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the mammalian kidney. (1980) (5)
- Postnatal development of urea concentration in the newborn rabbit's kidney. (1971) (4)
- Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. (2021) (4)
- Corrigendum to “Interaction of human organic anion transporters with various cephalosporin antibiotics” [Eur. J. Pharmacol. 438 (2001) 137–142] (2002) (4)
- Functional expression of the rat organic anion transporter 1 (rOAT1) in Saccharomyces cerevisiae. (2005) (4)
- Nephrotoxicity of cisplatin in rats. (1986) (4)
- Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer (2020) (4)
- Establishment of a mouse macula densa cell line with an nNOS promoter driving EGFP expression. (2005) (4)
- Functional Analysis of Human Sodium-Phosphate Transporter 4 (NPT4/SLC17A3) Polymorphisms. (2011) (4)
- Analysis of uric acid transport via hOAT3. (2000) (4)
- L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation (2021) (4)
- Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture. (2006) (4)
- Attenuation of renomedullary phospholipase C isozyme, PLC‐δ1, in spontaneously hypertensive rats (1997) (4)
- Potassium-Retaining Diuretics: Aldosterone Antagonists (1995) (4)
- EZH2 Inhibitor GSK126: Metabolism, drug transporter and rat pharmacokinetic studies (2015) (4)
- Primary Metabolic and Renal Hyperuricemia (2009) (4)
- [Molecular mechanisms of drug transport]. (2000) (4)
- Contribution of purine nucleotide cycle to intranephron ammoniagenesis in rats. (1988) (4)
- Evidence suggesting a role for phospholipase C isozyme, PLC-delta 1 in corticomedullary osmotic gradients in rat kidneys. (1995) (4)
- Chapter 4 – Renal Basis of Hyperuricemia (2012) (4)
- [Urate transporter and renal hypouricemia]. (2003) (3)
- Intranephron distribution of creatine content in rats. (1994) (3)
- Renal gluconeogenesis in man: comparison with rats and rabbits. (1994) (3)
- Intra- and inter-nephron heterogeneity of gluconeogenesis in the rat: effects of chronic metabolic acidosis and potassium depletion (2004) (3)
- Cyclic AMP-dependent protein kinase activity and endogenous protein phosphorylation in isolated cortical segments of rabbit nephron. (1982) (3)
- Development of the alternative method for renal drug excretion using Xenopus oocyte expression system combined with a high throughput method, OOCYTEXPRESS ® (2008) (3)
- Orotic acid transport via organic anion transporters OATs. (2008) (3)
- Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma. (2017) (3)
- Intranephron ammoniagenesis and its regulation by PGE2 in rats and mice. (1988) (3)
- Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney (2020) (3)
- INTRANEPHRON DISTRIBUTION AND PROPERTIES OF XANTHINE OXIDASE, SUPEROXIDE DISMUTASE AND GUANASE ACTIVITIES IN CONTROL AND NEPHROTIC RATS (1987) (3)
- Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin’s lymphoma (2021) (2)
- Mutations in renal drug efflux transporter hOATv1 cause hyperuricemia (2010) (2)
- Intranephron distribution of epidermal growth factor immunoreactivity in the mouse. (1987) (2)
- A two-site solid phase enzyme immunoassay for rat epidermal growth factor. (1988) (2)
- Localization and properties of NAD-dependent 15 hydroxyprostaglandin dehydrogenase activity in spontaneously hypertensive rat kidney. (1986) (2)
- Characterization of Human Orgnic Anion Transporter 4 (hOAT4) as a Low Affinity p-aminohippurate (PAH) Transporter (2007) (2)
- A new approach for assessment of narcotic physical dependence using urinary sex-dependent low molecular weight proteins in male rats. (1983) (2)
- Attenuation of renomedullary phospholipase C isozyme, PLC-delta 1, in spontaneously hypertensive rats. (1997) (2)
- Cyclosporine Induces Apoptosis of Mouse Terminal Proximal Straight Tubule Cells (1998) (2)
- [The mechanisms of urate transport in the kidney and the intestine]. (1996) (2)
- [The pharmacogenomics of drug transporters: functional analysis approaches]. (2004) (2)
- Mouse Asc-1 (asc-type amino acid transporter 1) maps to chromosome 7, region B1-B5 (2004) (2)
- A novel Na(+)-dependent amino acid transporter with a high affinity to glutamine. (1997) (2)
- Cellular adenosine triphosphate production and consumption in the descending thin limb of Henle's loop in the rat. (1990) (2)
- Relationship between L-alanine and sodium ion transport in isolated renal tubules. (1975) (2)
- Functional heterogeneity of rat hepatocytes: predominance of aryl hydrocarbon hydroxylase activity in perivenular zone. (1988) (2)
- Inhibition of gluconeogenesis in rat renal cortex slices by metabolites of L-tryptophan in vitro (2004) (1)
- Distribution and Possible Functions of γ -Glutamyl-Transpeptidase in the Kidney (第23回日本腎臓学会総会 ) -- (ネフロンのheterogeneity(シンポジウム-3-)) (1981) (1)
- Primary Renal Uricosuria (2009) (1)
- Differential expression of system L amino acid transporters during wound healing process in the skin of young and old rats. (2008) (1)
- The identification and structural characterization of C7orf24 as γ-glutamyl cyclotransferase. An essential enzyme in the γ-glutamyl cycle. VOLUME 283 (2008) PAGES 22031-22042 (2008) (1)
- V1a receptor mRNA expression in mouse early proximal tubule (S1) cell line is regulated by protein kinase A (1998) (1)
- Renal Organic Solute Transporters: Relation to Serum (2010) (1)
- Identification of the multivalent PDZ domain protein PDZK1 as a binding partner of sodium‐coupled monocarboxylate cotransporter 2 (SMCT2) by yeast two‐hybrid assay (2008) (1)
- Interaction of a novel urate efflux transporter URATv1 (SLC2A9) with uricosuric agents. (2009) (1)
- Species differences in cellular adenosine triphosphate turnover within the nephron. (1991) (1)
- Endothelin receptor subtypes in rat kidney epithelial cells (1992) (1)
- Increased expression of the amino acid transporter LAT1 during healing of acetic acid-induced chronic gastric ulcers in rats (2006) (1)
- Renal Organic Solute Transporters: Relation to Serum Urate Disorder (2010) (1)
- Preferential Expression of L‐type Amino Acid Transporter 1 in Ameloblasts During Rat Tooth Development (2004) (1)
- [Drug-induced nephrotoxicity]. (1996) (1)
- CHAPTER 7 – Solute Transport, Energy Consumption, and Production in the Kidney (2008) (1)
- Mechanism of Ochratoxin A induced Nephropathy (1984) (1)
- Angiotensin II receptor subtypes in rat early proximal tubule. (1991) (1)
- High affinity D- and L-serine transporter Asc-1: Cloning and dendritic localization in the rat brain. (2004) (1)
- Treatment effects and predictors of a 24‐week course of interferon α‐2b plus ribavirin combination therapy for patients with chronic hepatitis C (2006) (1)
- Guanidinoacetic acid (GAA) synthesis in rat tubular suspension as a system for evaluating gentamicin (GM) nephrotoxicity. (1995) (1)
- [Molecular biology of urate transporter]. (2004) (1)
- Urinary sex-dependent low molecular weight proteins as a sign of narcotic dependence in male rats. (1983) (1)
- Cell type-specific activation of metabolism reveals that (cid:1) -cell secretion suppresses glucagon release from (cid:2) -cells in rat pancreatic islets (2005) (0)
- S1-4 Molecular Mechanisms of Permeation of Methylmercury through the Blood-Tissue Barriers.(Proceedings of the 27th Annual Meeting) (2000) (0)
- Subject Index, Vol. 12, 1989 (2004) (0)
- LAT 1 Is a Central Transporter of Essential Amino Acids in Human Umbilical Vein Endothelial Cells (2014) (0)
- Effects of cephaloridine (CER) on mouse terminal proximal straight tubule (S_3) cell lines expressing rat and human organic anion transporter-1 (OAT1) (1998) (0)
- The role of amino acid transporters in the cytotoxicity of methylmercury.(GENERAL SESSION BY POSTER PRESENTATION)(ENVIRONMENTAL CHEMICALS,HEAVY METALS & CYTOTOXICITY) (2002) (0)
- Nouvel anticorps anti-cd98 (2007) (0)
- Changes in protein excretion from rat kidney during administration of Angiotensin II and its analogues (1978) (0)
- Effect of deoxycorticosterone acetate on ammoniagenesis in isolated nephron segments of rats (1984) (0)
- Effects of MK 870 and Pteridine Derivatives on the Toad Bladder (1968) (0)
- EFFECTS OF MERCURY ON THE STRUCTURAL PROTEINS OF VARIOUS SEGMENTS IN ISOLATED NEPHRON (The Fourth Meeting for the Study of Toxic Effect) (1977) (0)
- Cis-platinum(II)-diamino dichloride(CDDP) induced toxicity in immortalized cell lines established from each nephron segment of transgenic mice harboring ts-SV40 T-antigen gene. (1993) (0)
- 215. TOXIC ACTION OF HEAVY METALS. 2. ANALYSIS OF PROTEINURIA DUE TO MERCURY (The Third Meeting for the Study of Toxic Effect) (1977) (0)
- Isoform Selectivity of 3125 I-Iodo-- Methyl-L-Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (0)
- Gender differences in expression of rat renal OAT1 (2003) (0)
- Sodium-dependent transport activity for l-DOPA in Xenopus laevis oocyte injected with polya+ RNA from rabbit intestinal epithelium (1998) (0)
- Functional properties and distribution of expression of neutral amino acid transporters in the central nervous system (1997) (0)
- Molecular mechanisms of drug transport (2000) (0)
- MOUSE RST FACILITATES TRANSCELLULAR TRANSPORT OF ORGANIC ANIONS BY A COORDINATION OF BASOLATERAL ORGANIC ANIO N TRANSPORTERS (OAT3 ) (2004) (0)
- Human Nramp2 as a cadmium transporter.(GENERAL SESSION BY POSTER PRESENTATION)(ENVIRONMENTAL CHEMICALS,HEAVY METALS & CYTOTOXICITY) (2002) (0)
- Targeting leukemia metabolism or essential amino acid uptake shows anti-tumoral activity in PTEN-deficient T-cell mouse lymphomas and T-ALL/T-LL human cells (2014) (0)
- Characteristics of the isolated kidney cell recognized specifically with the monoclonal antibody (γG6) (1983) (0)
- W2-1 SIGNIFICANCE OF ALTERNATIVE TOXICITY TESTING (1989) (0)
- Attenuation of response to ANG II in adult spontaneously hypertensive rats kidney (1996) (0)
- C-17 IDENTIFICATION OF A NOVEL LIVER SPECIFIC ORGANIC ANION TRANSPORTER SELECTIVE FOR CONJUGATED DRUGS AND STEROID HORMONES (2003) (0)
- Cellular atp production and consumption in the descending thin limb of henle's loop in the rat (1990) (0)
- 21D-02-2 Involvement of Organic Anion Transporter1 (OAT1) in the Development of Renal Toxicity Related to Anionic Substances. (1999) (0)
- P7-56 Identification of novel system L transporters and their methyl mercury-cysteine conjugates transport properties(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting) (2004) (0)
- Pharmacological inhibition of the amino-acid transporter LAT1 demonstrates in vitro anti-neoplastic activity towards medulloblastoma (2018) (0)
- RELATIONSHIP BETWEEN γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY IN URINE AND RENAL PROXIMAL TUBULAR DAMAGE(S) BY NEPHROTOXIC AGENTS (The 6th Meeting for the Study of Toxic Effect) (1979) (0)
- Induction of rat hepatic CYP 1A1, 1B1, and AhR by 7, 12-dimethylbenz[α]anthracene on prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Drug metabolism, Proceedings of the 32nd Annual Meeting) (2005) (0)
- Human Drug Transporter Gene-expressing Cells are Useful Alternatives to Predict Pharmacokinetics in Man (2011) (0)
- Neutral amino acids transporter and corresponding gen (1999) (0)
- Intranephron localization of 15-hydroxyprostaglandin dehydrogenase in the rat. (1983) (0)
- Endothelin Increases Intracellular Free Calcium in Isolated Rat Nephron (1997) (0)
- Identification and functional characterization of a novel cationic amino acid transporter CAT5 specifically expressed in placenta (2006) (0)
- Amino Acids for Immune Reactions in LAT1 Is a Critical Transporter of Essential (2013) (0)
- S1-2 Role of drug transporters in druginduced nephrotoxicity(Proceedings of the 27th Annual Meeting) (2000) (0)
- Organic anion transporter 4 (OAT4) interacts with two PDZ Domain Proteins (2005) (0)
- Method of Ultramicro-Analysis of Proteins Using 1-Dimethylamino-Naphthalene-5-Sulfonyl Chloride (DNS-CL) (1972) (0)
- Evaluation of testicular toxicology in puberty to adult rats with prenatal exposure for 3, 3', 4, 4', 5-pentachlorobiphenyl(Proceedings of the 32nd Annual Meeting) (2005) (0)
- The Increasing Effect of Bee-Venom on the Sodium Transport of the Toad Bladder (1968) (0)
- 新規尿酸トランスポーターURATv1(SLC2A9)遺伝子変異と腎性低尿酸血症 (2009) (0)
- Acid-base, nephrolithiasis and divalent ions (2009) (0)
- [Micromethods for the determination of metabolic characteristics in individual nephron segments]. (1994) (0)
- Characterization of alpha-fetoprotein secreted from cultured reuber H-35 hepatoma cells (1982) (0)
- H2O2-induced apoptosis In mouse proximal straight tubule (S3) cell line (II) (1996) (0)
- L-TYPE AMINO ACID TRANSPORTER 1 EXPRESSION IN PROSTATE CANCER: ASSOCIATION WITH CANCER PROGRESSION AND HIGH-GRADE MALIGNANCY (2008) (0)
- Silica increases cytosolic calcium and causes cell injury in renal cell lines. (1999) (0)
- Direct Effect of Tetragastrin, Caerulein and Pancreozymin on the Enzyme Secretion of the Rabbit Pancreas (1972) (0)
- Role of the inhibitory effect of tetrodotoxin on the active sodium transport of the toad bladder (2004) (0)
- Kidney-specific urate transporter and its gen (2002) (0)
- Preventive and therapeutic agent against phosphorus disorder, oral agent for the adsorption of phosphate ions in foods, beverages and chemical and manufacturing processes (2006) (0)
- Functional characterization of a novel urate efflux transporter URATv1 (SLC2A9) and its relation to renal hypouricemia. (2009) (0)
- Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation. (2021) (0)
- Interaction of the multivalent PDZ domain protein PDZK1 with novel liver‐specific organic anion transporter 7 (OAT7) (2008) (0)
- The A BC o f S olute C arriers (2004) (0)
- Pathophysiological role of a Novel Vasopressin Receptor (Vp) in isolated SHRSP nephron segments (1992) (0)
- [Relationship between the decrease in urinary sex-dependent low molecular weight proteins by morphine and hormonal parameters in male rats]. (1983) (0)
- Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1 (2022) (0)
- Effects of 3-methylcholanthrene and starvation on intranephron distribution of cytochrome P-450. (1983) (0)
- Expression of a system L amino acid transporter at testis of rats after prenatal exposure to di(n-butyl)phate(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting) (2005) (0)
- A TSUSHI ENOMOTO,*t MICHIO TAKEDA, t AKIHI.RO TOJO,t T AKASHI SEKINE, t§ (2002) (0)
- [Mechanism of renal transport of potassium]. (1981) (0)
- Functional Characterization and Organic Anion Transporter Immunohistochemical 1 ( Slc 22 a 6 ) fromMouse Localization of Kidney (2014) (0)
- Intranephron Distribution of Insulin Binding in Wistar Kyoto and Spontaneously Hypertensive Rats (1989) (0)
- Functional Characterization and Immunohistochemical Localization of Organic Anion Transporter 1 (S1c22a6) from Mouse Kidney (2004) (0)
- ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO (1986) (0)
- MON-470 Pharmacological Inhibition of LAT1 Suppresses Proliferation and Hormone Synthesis in Rat Pituitary Tumor GH4 Cells [cc1] Synthesis May Be Better as Only mRNAs Were Measured (2019) (0)
- Establishment of early proximal tubule (Si) cell line selectively expressing V1a receptor derived from transgenic mice harboring SV40 large T-antigen gene (1995) (0)
- Relation between serum human albumin level and serum urate level in the chimeric mice having human hepatocytes. (2008) (0)
- Transport of Methylmercury through the Epithelial Type Amino Acid Transporter System B0 (2019) (0)
- Functional Analysis of Human Sodium-Phosphate Transporter 4 ( NPT 4 / SLC 17 A 3 ) Polymorphisms (2011) (0)
- P-22 Protective effects of N-acetylcysteine, a precursor of glutathione, on teratogenicity of cadmium chloride in mice.(Proceedings of the 27th Annual Meeting) (2000) (0)
- 103. EFFECT OF MERCURY ON THE NEWT KIDNEY (The Second Meeting for the Study of Toxic Effect) (1976) (0)
- Transport of nicotinate by human organic anion transporters of SLC22 family (2006) (0)
- PCR cloning of Na+-dependent L-alanine transporter SNAT2(ASCT2B) gene from rat kidney. (1996) (0)
- A new ultramicro analysis of protein by S.D.S. polyacrylamide gel electrophoresis. (1974) (0)
- Investigation of expression of a system L neutral amino acid transporter LAT1 and its biological role in human glioma cells (2004) (0)
- VECTORIAL TRANSPORT OF ORGANIC ANIONS ACROSS LLC-PK1 CELL MONOLAYERS (2004) (0)
- Implications of free radicals for nephropathy and their scavenging agents. (1996) (0)
- Drug transport studies by human MDR1 in Xenopus laevis oocyte expression system (2008) (0)
- The multivalent PDZ domain protein PDZK1 upregulates the transport activity of renal urate-anion exchanger URAT1 via its C-terminal (2004) (0)
- Expression of LAT1 predicts progression of transitional cell carcinoma of the upper urinary tract (2006) (0)
- Current Status and Future Perspective on Molecular Toxicology (KEYNOTE LECTURE) (Proceedings of the 30th Annual Meeting) (2003) (0)
- Distinct Interleukin-1β-converting enzyme (ICE) family proteases mediate cisplatin (CDDP)- and staurosporine (STS)- induced apoptosis of mouse terminal proximal tubule (S_3) cells (1998) (0)
- Anti-tumor effects of L-type amino acid transporter 1 (LAT1) inhibitor in a syngeneic and orthotropic mouse model for melanoma (2019) (0)
- Distribution and Properties of Intranephron Prostaglandin E2 Production in Wistar Kyoto and Stroke Prone Spontaneously Hypertensive Rats (1988) (0)
- A NEW ULTRAMICRO ANALYSIS OF PROTEIN BY S.D.S.<SUP>1</SUP> POLYACRYLAMIDE GEL ELECTROPHORESIS (2006) (0)
- Uricosuric agents and renal tubular transporters (2011) (0)
- In vitro Thermoreversible Gel Disc Quantitative Assay of Rat Angiogenesis (2011) (0)
- Progress in nephrotoxicology: from in vivo screening test to molecular mechanisms. (1998) (0)
- Role of ammonium ion in adenosine triphosphate consumption of the rat medullary thick ascending limb. (1991) (0)
- Partial purification of the antidiuretic hormone receptor from the rabbit kidney. (1983) (0)
- Suppression of tumor angiogenesis by inhibition of LAT1 in stromal endothelial cells (2019) (0)
- Transport of methylmercury through the epithelial type amino acid transport system B^0(Proceedings of the 32nd Annual Meeting) (2005) (0)
- 143 – EFFECTS OF ANGIOTENSIN IE AND ITS ANALOGUES ON PROTEINURIA IN RAT (1978) (0)
- Suppressive effects of LAT1 specific inhibitor on allergic skin inflammation (2019) (0)
- 1126: A New Classification of Phenotype-Genotype of Cystinuria Patients in Japan (2004) (0)
- PROGRESS INNEPHROTOXICOLOGY : TEST TO MOLECULAR FROM IN VIVO SCREENING MECHANISMS (2018) (0)
- [Usefulness of microdissection of nephron segments and fluorescent indicator for molecular biological studies of nephron functions]. (1992) (0)
- Organic anion transporter (OAT) family: the role as a drug transporter family (2000) (0)
- Molecular aspects of the aldosterone effect on the developing rat kidney (1992) (0)
- Narcotic physical dependence and urinary sex-dependent low molecular weight proteins in male rats. (1983) (0)
- [Advances in the biochemical and immunohistochemical study of kidney tubule transport]. (1989) (0)
- Roles of glutamate transporters in neuronal cell death (1994) (0)
- Abstract 5286: Expression of cancer type amino acid transporter LAT1 is a prognosis prediction factor in breast carcinoma: comparison between triple-negative and non-triple-negative types (2015) (0)
- Identification and Characterization of a Na 1 -independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral D - and L -Amino Acids* (2000) (0)
- Micropuncture study of protein concentration in glomerular fluid in the newt. (1971) (0)
- 1125: Identification of A Novel Missense Mutation of SLC7A9 Frequent in Japanese Cystinuria Population that Cause Membrane Targeting Defect of the Transporter Protein by Introducing A Bulky Side Chain on its C -Terminus (2004) (0)
- Functional characterization of urate transport via a novel urate efflux transporter URATv1. (2009) (0)
- N-methyl-N-nitrosourea induced rat prostate carcinogenesis is modulated by prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Proceedings of the 32nd Annual Meeting) (2005) (0)
- Human urate transporter 1 (URAT1) mediates orotic acid transport (2007) (0)
- CBMS-05 COMPREHENSIVE METABOLOMIC ANALYSIS OF IDH1R132H CLINICAL GLIOMA SAMPLES REVEALS SUPPRESSION OF Β-OXIDATION DUE TO CARNITINE DEFICIENCY (2019) (0)
- Agonists stimulated cAMP response in renal cell lines established from transgenic mice harboring SV40 large T antigen gene. (1994) (0)
- Role of intracellular C‐terminal domain of the catalytic subunit of system b0,+ for its trafficking and the RACK1 binding. (2006) (0)
- Acute renal failure - basic research (2009) (0)
- [Organic ion transporter family]. (2001) (0)
- Effects of aminonucleoside on renal function. (1972) (0)
- P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2. (1998) (0)
- 363 – GLUCOSE DEHYDROGENASE (HEXOSE 6-PHOSPHATE DEHYDROGENASE) AS SUPPLIER OF REDUCED PYRIDINE NUCLEOTIDES FOR MICROSOMAL ELECTRON TRANSPORT SYSTEM (1978) (0)
- Use of hydantoin derivatives for the manufacture of a medicament for the treatment of diseases associated with active Sauestoff and free radicals (1996) (0)
- [Identification of a novel urate transporter URAT1 and current status on urate research]. (2003) (0)
- Transporter-mediated toxicity in the nephrotoxicity of organic compounds(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting) (2005) (0)
- 7th European Colloquium on Renal Physiology (Part 2 of 3) (1992) (0)
- Erratum to “Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters” [Eur. J. Pharmacol. 419 (2001) 113–120] (2002) (0)
- Pathophysiological Significance of a Novel Vasopressin Receptor (Vp) in Stroke-prone Spontaneously Hypertensive Rat Kidneys (1995) (0)
- Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets. (2006) (0)
- Functional characterization and tissue localization of a novel liver‐specific organic anion transporter OAT7 (2006) (0)
- Contents, Vol. 12, 1989 (1989) (0)
- 7th European Colloquium on Renal Physiology (Part 1 of 3) (1992) (0)
- Effect of Mercuric Chloride on Angiotensin II-Induced Ca ++ Transient in the Proximal Tubule of Rats (1991) (0)
- A21 RELATIONSHIP BETWEEN CELLULAR ATP AND CYTOSOLIC CALCIUM IN NEPHROTOXIC MANIFESTATION (1989) (0)
- Molecular identification of a novel prostaglandin‐specific organic anion transporter (OAT‐PG) that is colocalized with prostaglandin producing enzyme Cox‐2 in the distal tubular cells. (2006) (0)
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What Schools Are Affiliated With Hitoshi Endou?
Hitoshi Endou is affiliated with the following schools: