Hitoshi Endou

Q: What Schools Are Affiliated With Hitoshi Endou

Hitoshi Endou is affiliated with the following schools: University of Tokyo, Kyorin University

Hitoshi Endou's AcademicInfluence.com Rankings

Hitoshi Endou

Medical

#2141

World Rank

#2543

Historical Rank

Pharmacology

#222

World Rank

#262

Historical Rank

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Medical

Hitoshi Endou's Degrees

PhD Pharmacology University of Tokyo
Masters Pharmacology University of Tokyo
Bachelors Pharmacy University of Tokyo

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Hitoshi Endou's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular identification of a renal urate–anion exchanger that regulates blood urate levels (2002) (1280)
Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)* (1998) (968)
CATs and HATs: the SLC7 family of amino acid transporters (2004) (682)
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. (2001) (645)
Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter* (1997) (636)
The SLC22 drug transporter family (2004) (504)
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. (2001) (495)
Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter* (1996) (494)
Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain* (1999) (483)
Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity* (1999) (480)
Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta* (2000) (394)
Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. (2002) (373)
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver (1998) (347)
Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. (2004) (343)
Identification and characterization of the high-affinity choline transporter (2000) (330)
The multispecific organic anion transporter (OAT) family (2000) (321)
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans* (2008) (319)
Molecular physiology of urate transport. (2005) (315)
Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. (2002) (279)
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (272)
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity. (2002) (271)
Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities (1999) (261)
Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids* (2000) (256)
Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters (2002) (249)
L‐type amino acid transporter 1 as a potential molecular target in human astrocytic tumors (2006) (235)
Expression Cloning of a Na+-independent Aromatic Amino Acid Transporter with Structural Similarity to H+/Monocarboxylate Transporters* (2001) (233)
Molecular physiology of renal organic anion transporters. (2006) (229)
T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. (1999) (227)
Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney. (2002) (226)
Identification of a Novel System L Amino Acid Transporter Structurally Distinct from Heterodimeric Amino Acid Transporters* (2003) (225)
Uric Acid Causes Vascular Smooth Muscle Cell Proliferation by Entering Cells via a Functional Urate Transporter (2005) (222)
L‐type amino‐acid transporter 1 as a novel biomarker for high‐grade malignancy in prostate cancer (2009) (218)
Characterization of uremic toxin transport by organic anion transporters in the kidney. (2004) (218)
l‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth (2010) (211)
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. (2004) (204)
Organic anion transporter family: current knowledge. (2006) (203)
Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I–III nonsmall cell lung cancer (2008) (198)
Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. (2002) (186)
Interactions of Human Organic Anion Transporters and Human Organic Cation Transporters with Nonsteroidal Anti-Inflammatory Drugs (2002) (185)
Molecular Identification of a Novel Carnitine Transporter Specific to Human Testis (2002) (184)
New insights into renal transport of urate (2007) (183)
Interactions of Human Organic Anion Transporters with Diuretics (2004) (181)
The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus* (2004) (179)
Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier (2001) (179)
Identification of an Amino Acid Transporter Associated with the Cystinuria-related Type II Membrane Glycoprotein* (1999) (178)
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. (2004) (168)
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease (2005) (168)
Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney. (1999) (167)
A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters (2005) (166)
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. (1999) (164)
Intrarenal handling of proteins in rats using fractional micropuncture technique. (1992) (157)
Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. (2001) (154)
Function and localization of urate transporter 1 in mouse kidney. (2004) (150)
Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. (2002) (149)
Role of human organic anion transporter 4 in the transport of ochratoxin A. (2002) (148)
Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. (2001) (148)
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. (2002) (144)
Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats (2001) (143)
Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. (2002) (142)
Expression of a system L neutral amino acid transporter at the blood–brain barrier (2000) (141)
l‐type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms (2008) (141)
Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. (2002) (134)
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. (1999) (131)
Substrate specificity to maintain cellular ATP along the mouse nephron. (1988) (130)
Human Sodium Phosphate Transporter 4 (hNPT4/SLC17A3) as a Common Renal Secretory Pathway for Drugs and Urate* (2010) (130)
Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis (2006) (130)
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. (2002) (130)
Human vascular smooth muscle cells express a urate transporter. (2006) (129)
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. (2000) (123)
LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells (2013) (122)
Urate transport via human PAH transporter hOAT1 and its gene structure. (2003) (120)
Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. (2001) (119)
Novel nonsense mutation in the Na+/HCO3- cotransporter gene (SLC4A4) in a patient with permanent isolated proximal renal tubular acidosis and bilateral glaucoma. (2001) (117)
BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. (2008) (116)
Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth. (2016) (116)
Interaction of human organic anion transporters with various cephalosporin antibiotics. (2002) (114)
Identification of a Novel Voltage-driven Organic Anion Transporter Present at Apical Membrane of Renal Proximal Tubule* (2003) (113)
Characterization of ochratoxin A transport by human organic anion transporters. (2001) (112)
Transport of 3-Fluoro-l-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET (2012) (112)
Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports d-serine with high affinity (2000) (111)
High expression of L‐type amino‐acid transporter 1 (LAT1) in gastric carcinomas: Comparison with non‐cancerous lesions (2011) (110)
Novel liver‐specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate (2007) (108)
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese. (2004) (107)
Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine. (1998) (106)
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. (2005) (105)
Fluorine-18-α-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer: A Clinicopathologic Study (2007) (104)
Transport of ochratoxin A by renal multispecific organic anion transporter 1. (1998) (104)
The multispecific organic anion transporter family: properties and pharmacological significance. (2004) (103)
Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites. (2003) (98)
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. (1999) (98)
Contribution of Organic Anion Transporters to the Renal Uptake of Anionic Compounds and Nucleoside Derivatives in Rat (2003) (98)
The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5) (2018) (98)
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. (2002) (96)
Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors. (2004) (91)
Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. (2001) (91)
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia (2014) (90)
Human organic anion transporters mediate the transport of tetracycline. (2002) (88)
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (88)
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs (2011) (86)
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. (2003) (85)
Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules (2005) (84)
Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. (2001) (82)
Transient upregulation of the glial glutamate transporter GLAST in response to fibroblast growth factor, insulin-like growth factor and epidermal growth factor in cultured astrocytes. (2001) (81)
Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (81)
Interactions of human organic anion as well as cation transporters with indoxyl sulfate. (2003) (81)
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc (2019) (80)
Quantitative Evaluation of the Drug-Drug Interactions between Methotrexate and Nonsteroidal Anti-Inflammatory Drugs in the Renal Uptake Process Based on the Contribution of Organic Anion Transporters and Reduced Folate Carrier (2004) (79)
Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions. (2004) (78)
Differential gene expression of organic anion transporters in male and female rats. (2002) (78)
Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity. (2003) (78)
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia (2004) (78)
System l-amino acid transporters are differently expressed in rat astrocyte and C6 glioma cells (2004) (77)
The genetic polymorphism of drug transporters: functional analysis approaches. (2004) (77)
Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract (2007) (75)
Identification of a Novel Na+-independent Acidic Amino Acid Transporter with Structural Similarity to the Member of a Heterodimeric Amino Acid Transporter Family Associated with Unknown Heavy Chains* (2002) (73)
Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid. (2008) (72)
Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation. (2001) (72)
Cadmium transport by human Nramp 2 expressed in Xenopus laevis oocytes. (2003) (71)
Hydrogen Peroxide Induces Necrosis, Apoptosis, Oncosis and Apoptotic Oncosis of Mouse Terminal Proximal Straight Tubule Cells (1999) (71)
Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. (2004) (70)
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. (2001) (69)
Localization of 25-hydroxyvitamin D3-lα-hydroxylase activity in the mammalian kidney (1980) (69)
High affinity d- and l-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices (2004) (68)
Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3). (2000) (68)
Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters. (2008) (68)
Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. (2004) (67)
Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. (2002) (67)
Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout (2009) (67)
Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells. (2008) (66)
Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas. (2003) (66)
High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas (2012) (66)
A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout. (2005) (65)
c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells. (2012) (63)
Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis (2011) (62)
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis (2004) (62)
Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung. (2008) (62)
Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. (2002) (61)
Effect of fenofibrate on uric acid metabolism and urate transporter 1. (2010) (61)
Two male siblings with hereditary renal hypouricemia and exercise-induced ARF. (2003) (61)
Renal urate handling: Clinical relevance of recent advances (2005) (59)
Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney. (2000) (59)
The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. (2004) (58)
Pathogenesis of adult-onset type II citrullinemia caused by deficiency of citrin, a mitochondrial solute carrier protein: tissue and subcellular localization of citrin. (2001) (58)
Correlation of angiogenesis with 18F‐FMT and 18F‐FDG uptake in non‐small cell lung cancer (2009) (58)
Cisplatin-induced toxicity in immortalized renal cell lines established from transgenic mice harboring temperature sensitive SV40 large T-antigen gene (1996) (57)
Molecular Mechanism of Ochratoxin A Transport in the Kidney (2010) (56)
L‐type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non‐small cell lung cancer (2009) (56)
Furosemide directly stimulates prostaglandin E2 production in the thick ascending limb of Henle's loop. (1989) (55)
JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells. (2014) (54)
Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3. (2006) (54)
Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction (2006) (54)
Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction. (2005) (54)
Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia. (2005) (53)
Metabolism and pharmacokinetic studies of JPH203, an L-amino acid transporter 1 (LAT1) selective compound. (2012) (53)
Involvement of H2O2 production in cisplatin-induced nephrotoxicity. (1998) (52)
Cytochrome P-450 monooxygenase system in the rabbit kidney: its intranephron localization and its induction. (1983) (52)
Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions. (2004) (51)
Prognostic significance of L‐type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung (2009) (50)
Association between GLUT9 and gout in Japanese men (2010) (50)
Altered renal elimination of organic anions in rats with chronic renal failure. (2005) (50)
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. (2004) (49)
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2. (1998) (49)
LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung (2006) (48)
Nephrotoxicity assessment by measuring cellular ATP content. I. Substrate specificities in the maintenance of ATP content in isolated rat nephron segments. (1989) (46)
Functional analysis of human organic cation transporter OCT3 (SLC22A3) polymorphisms. (2010) (46)
The RNA interference of amino acid transporter LAT1 inhibits the growth of KB human oral cancer cells. (2006) (46)
Interactions of organic anion transporters and organic cation transporters with mycotoxins. (2008) (45)
First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors (2020) (45)
Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule (2005) (44)
Integrated physiology of proximal tubular organic anion transport (2005) (44)
Developing potent human uric acid transporter 1 (hURAT1) inhibitors. (2011) (44)
Elimination of Organic Anions in Response to an Early Stage of Renal Ischemia-Reperfusion in the Rat: Role of Basolateral Plasma Membrane Transporters and Cortical Renal Blood Flow (2007) (44)
Inhibition of l-type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment (2017) (43)
Distribution of gamma-glutamyl transpeptidase and glutaminase isoenzymes in the rabbit single nephron. (1982) (43)
Cisplatin-induced apoptosis of immortalized mouse proximal tubule cells is mediated by interleukin-1β converting enzyme (ICE) family of proteases but inhibited by overexpression of Bcl-2 (1997) (43)
Urate transporters: an evolving field. (2011) (42)
Evaluation of thoracic tumors with 18F‐FMT and 18F‐FDG PET‐CT: A clinicopathological study (2009) (42)
Human cystinuria-related transporter: localization and functional characterization. (2001) (42)
Nephrotoxicity assessment by measuring cellular ATP content. II. Intranephron site of ochratoxin A nephrotoxicity. (1989) (41)
Protein characterization of NA+-independent system L amino acid transporter 3 in mice: a potential role in supply of branched-chain amino acids under nutrient starvation. (2007) (41)
Nephron heterogeneity: gluconeogenesis from pyruvate in rabbit nephron (1980) (40)
L‐type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas (2009) (40)
The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. (2006) (39)
Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B. (2004) (39)
A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules* (2010) (38)
Lipid peroxidation in isolated rat nephron segments. (1992) (37)
An adenosine deaminase inhibitor prevents puromycin aminonucleoside nephrotoxicity. (1997) (37)
A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter. (2006) (37)
Urate Transport Across the Apical Membrane of Renal Proximal Tubules (2008) (37)
Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells. (2005) (37)
Oxidative stress and chronic allograft nephropathy. (2004) (36)
Involvement of Multiple Transporters in the Efflux of 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors across the Blood-Brain Barrier (2004) (36)
Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs. (2004) (36)
Purinoceptor-mediated calcium mobilization and cellular proliferation in cultured bovine corneal endothelial cells. (2000) (34)
Functional and Immunochemical Characterization of a Novel Organic Anion Transporter Oat8 (Slc22a9) in Rat Renal Collecting Duct (2008) (34)
Interactions of human organic anion transporters with aristolochic acids. (2010) (32)
Effects of in Utero Exposure to Di(n-butyl) Phthalate for Estrogen Receptors α, β, and Androgen Receptor of Leydig Cell on Rats (2014) (32)
High expression of L-type amino acid transporter 1 as a prognostic marker in bile duct adenocarcinomas (2014) (32)
Effect of P2Y-purinoceptor stimulation on renal gluconeogenesis in rats. (1995) (31)
Nephrin and podocin expression around the onset of puromycin aminonucleoside nephrosis. (2005) (31)
Intranephron distribution of cysteine S -conjugate β-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats (1997) (31)
Hydrogen peroxide downregulates human organic anion transporters in the basolateral membrane of the proximal tubule. (2000) (30)
Characterization of 3-[125I]iodo-alpha-methyl-L-tyrosine transport via human L-type amino acid transporter 1. (2003) (29)
Expression and functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells. (2004) (29)
Mouse organic anion transporter 2 (mOat2) mediates the transport of short chain fatty acid propionate. (2008) (28)
Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. (2007) (28)
Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride (2009) (28)
Apical Voltage-Driven Urate Efflux Transporter NPT4 in Renal Proximal Tubule (2011) (28)
Recent advances in molecular mechanisms of nephrotoxicity. (1998) (28)
LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells. (2016) (28)
Isoform selectivity of 3-125I-iodo-alpha-methyl-L-tyrosine membrane transport in human L-type amino acid transporters. (2003) (28)
Unique and selective expression of L-amino acid transporter 1 in human tissue as well as being an aspect of oncofetal protein. (2014) (27)
Glucose dehydrogenase (hexose 6-phosphate dehydrogenase) and the microsomal electron transport system. Evidence supporting their possible functional relationship. (1979) (27)
Biosynthesis of Guanidinoacetic Acid in Isolated Renal Tubules (1992) (26)
Children's toxicology from bench to bed--Drug-induced renal injury (3): Drug transporters and toxic nephropathy in childhood. (2009) (26)
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation (2020) (26)
Distinct interleukin-1β-converting enzyme family proteases mediate cisplatin- and staurosporine-induced apoptosis of mouse proximal tubule cells (1998) (26)
Oat5 and NaDC1 Protein Abundance in Kidney and Urine After Renal Ischemic Reperfusion Injury (2009) (26)
Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells. (2006) (26)
Inhibition of L-type amino acid transporter modulates the expression of cell cycle regulatory factors in KB oral cancer cells. (2010) (26)
Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3. (2004) (26)
Cisplatin-induced alterations in renal structure, ammoniagenesis and gluconeogenesis of rats. (1992) (26)
Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney. (2003) (26)
Expression of L-type amino acid transporter 1 in a rat model of liver metastasis: positive correlation with tumor size. (2001) (26)
JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells (2017) (25)
Intra- and inter-nephron heterogeneity of ammoniagenesis in rats: effects of chronic metabolic acidosis and potassium depletion (1986) (25)
A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter. (2009) (25)
Involvement of rBAT in Na(+)-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA. (2000) (24)
Inhibition of the amino‐acid transporter LAT1 demonstrates anti‐neoplastic activity in medulloblastoma (2019) (24)
P 2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P 2 Y 1 and P 2 Y 2 (1998) (23)
Human urate transporter 1 (hURAT1) mediates the transport of orotate (2011) (22)
Atypical Leydig Cell Hyperplasia in Adult Rats with Low T and High LH Induced by Prenatal Di(n-butyl) Phthalate Exposure (2013) (22)
Inhibitory effect of cyclic AMP on phorbol ester-stimulated production of reactive oxygen metabolites in rat glomeruli. (1989) (22)
Biphasic increasing effect of angiotensin-II on intracellular free calcium in isolated rat early proximal tubule. (1989) (22)
Renal Solute Transporters and Their Relevance to Serum Urate Disorder (2010) (22)
Intracellular pH regulatory mechanism in a human renal proximal cell line (HKC-8): evidence for Na+/H+ exchanger, Cl–/HCO3– exchanger and Na+-HCO3– cotransporter (2000) (22)
FUNCTIONAL INVOLVEMENT OF RAT ORGANIC ANION TRANSPORTER 2 (SLC22A7) IN THE HEPATIC UPTAKE OF THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG KETOPROFEN (2005) (21)
Metformin enhances anti-tumor effect of L-type amino acid transporter 1 (LAT1) inhibitor. (2016) (21)
Interactions of Stevioside and Steviol with Renal Organic Anion Transporters in S2 Cells and Mouse Renal Cortical Slices (2005) (21)
Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo. (2010) (21)
L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa. (2007) (21)
Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway. (2007) (21)
Drug discovery for hyperuricemia (2007) (21)
Intranephron distribution of glycine-amidinotransferase activity in rats. (1992) (20)
Rapid Elimination of Cefaclor from the Cerebrospinal Fluid Is Mediated by a Benzylpenicillin-Sensitive Mechanism Distinct from Organic Anion Transporter 3 (2005) (20)
L-amino acid transporter 1 may be a prognostic marker for local progression of prostatic cancer under expectant management. (2015) (20)
L-Type amino acid transporter 1 (LAT1) expression in lymph node metastasis of gastric carcinoma: Its correlation with size of metastatic lesion and Ki-67 labeling. (2015) (20)
Distribution and some characteristics of cytochrome P-450 in the kidney. (1983) (20)
Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene. (2006) (19)
[Evaluation of nephrotoxic site in rat proximal tubule: intrarenal distributions of three enzymes and effects of mercuric chloride and gentamicin on their excretion into urine (author's transl)]. (1980) (19)
Identification of a Novel Organic Anion Transporter Mediating Carnitine Transport in Mouse Liver and Kidney (2010) (19)
Effect of chronic metabolic acidosis on ammonia production fromL-glutamine in microdissected rat nephron segments (1985) (19)
Cisplatin-induced apoptosis in mouse proximal tubular cell line. (1996) (19)
Male Sprague-Dawley Rats Exposed to In Utero Di(n-butyl) Phthalate (2013) (19)
Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus. (2004) (18)
Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters. (2004) (18)
Renal drug transporters and nephrotoxicity (2006) (17)
Nicergoline enhances glutamate uptake via glutamate transporters in rat cortical synaptosomes. (2004) (17)
Spermatogenesis in aged rats after prenatal 3,3',4,4',5-pentachlorobiphenyl exposure. (2007) (16)
Involvement of macromolecule synthesis, endonuclease activation and c-fos expression in cisplatin-induced apoptosis of mouse proximal tubule cells. (1998) (16)
ATP‐induced calcium mobilization in glomerular mesangial cells is mediated by P2U purinoceptor (1996) (16)
Mercury chloride as a possible phospholipase C activator: effect on angiotensin II-induced [Ca++]i transient in the rat early proximal tubule. (1990) (16)
[Human renal urate transpoter URAT1 mediates the transport of salicylate]. (2010) (16)
Amino acid transporters: molecular structure and physiological roles. (2000) (16)
CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl. (2005) (16)
Intranephron heterogeneity of ammoniagenesis and gluconeogenesis in rats. (1985) (15)
Solute Transport, Energy Consumption, and Production in the Kidney (2013) (15)
Investigation of the role of transporters on the hepatic elimination of an LAT1 selective inhibitor JPH203. (2013) (15)
Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (15)
First-in-human phaseIstudy of JPH203 in patients with advanced solid tumors. (2018) (14)
Establishment of vasopressin-responsive early proximal tubular cell lines derived from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. (1995) (14)
Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. (2010) (14)
Sex-associated difference in estrogen receptor β expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats. (2011) (14)
Cell type-specific activation of metabolism reveals that β-cell secretion suppresses glucagon release from α-cells in rat pancreatic islets (2006) (13)
A novel vasopressin receptor in rat early proximal tubule. (1991) (13)
Hyperoxia inhibits nitric oxide treatment effects in alveolar epithelial cells via effects on L-type amino acid transporter-1. (2014) (13)
Localization of kallikrein-like activity along a single nephron in rabbits (2004) (13)
Evaluation of nephrotoxicity using isolated nephron segments. (1986) (12)
Relationship between chronic treatment with morphine and sex-dependent low molecular weight protein excretion. (1981) (12)
Isolation by monoclonal antibody of intercalated cells of rabbit kidney. (1988) (12)
Effect of adenosine on phorbol myristate acetate induced-reactive oxygen metabolite production in cultured mesangial cells. (1996) (12)
Gene expression profiles in t24 human bladder carcinoma cells by inhibiting an l-type amino acid transporter, lat1 (2007) (11)
Biomarker Analyses in Patients With Advanced Solid Tumors Treated With the LAT1 Inhibitor JPH203 (2020) (11)
LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cells. (2014) (11)
Expression and Functional Characterization of Rat Organic Anion Transporter 3 ( rOat 3 ) in the Choroid Plexus (2002) (11)
LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation (2020) (11)
HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency (2016) (11)
Potent human uric acid transporter 1 inhibitors: in vitro and in vivo metabolism and pharmacokinetic studies (2012) (11)
Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms. (2011) (11)
Atrial natriuretic peptides stimulate renal gluconeogenesis. (1985) (11)
Suppressive effect of dipyridamole on the proteinuria of aminonucleoside nephrosis in rat. (1979) (10)
Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder. (1990) (10)
Kinetic studies on microsomal glucose dehydrogenase in rat liver. (1975) (10)
Furosemide acts on short loop of descending thin limb, but not on long loop. (1990) (10)
A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A. (2011) (10)
Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells. (2008) (10)
Distributional Patterns of Phospholipase C Isozymes in Rat Kidney (1998) (9)
Intranephron distribution of purine-metabolizing enzymes in rats. (1989) (9)
Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor (2020) (9)
L-type Amino Acid Transporter 1 Expression Increases in Well-Differentiated but Decreases in Poorly Differentiated Endometrial Endometrioid Adenocarcinoma and Shows an Inverse Correlation With p53 Expression (2014) (9)
Different sensitivity to nephrotoxic agents and osmotic stress in proximal tubular and collecting duct cell lines derived from transgenic mice. (2002) (9)
JPH 203 , an L-Type Amino Acid Transporter 1 – Selective Compound , Induces Apoptosis of YD-38 Human Oral Cancer Cells (2014) (8)
Effects of starvation on microsomal cytochrome P-450 and laurate-omega-hydroxylation of rat kidney and liver. (1983) (8)
[Arachidonic acid metabolites in the kidney]. (1990) (8)
First-in-human phase I study of JPH203, L-type amino acids transporter 1 inhibitor, in patients with advanced solid tumors. (2018) (8)
Quantitative analysis of electrophoretically separated proteins using Coomassie blue. (1978) (8)
Sequential increases in 4F2hc expression during DMBA-induced hamster buccal pouch carcinogenesis. (2003) (8)
Human Uric Acid Transporter 1 (hURAT1): An Inhibitor Structure–Activity Relationship (SAR) Study (2011) (7)
Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats. (2002) (7)
Ammonia production in cell lines established from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. (1994) (7)
Intranephron PGE2 production in stroke-prone spontaneously hypertensive rats. (1990) (7)
Time Course of Expression of 7,12-Dimethylbenz[a]anthracene-induced CYP1A1 and CYP1B1 mRNA and Protein in Rat Liver (2003) (7)
Alterations of gluconeogenesis by ischemic renal injury in rats. (1992) (7)
Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate (2013) (6)
Distribution and possible functions of gamma-glutamyl-transpeptidase in the kidney. (1981) (6)
1 A novel transporter of SLC 22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules (2010) (6)
Localization and properties of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in the rat kidney (1985) (6)
Testicular Toxicology of Pubescent and Adult Rats Prenatally Exposure to 3,3',4,4',5-Pentachlorobiphenyl (2007) (6)
Measurement of glutamate uptake and reversed transport by rat synaptosome transporters. (2004) (6)
Epidermal growth factor in the mouse kidney: developmental changes and intranephron localizations (2004) (6)
Molecular biology of multispecific organic anion transporter family (OAT family) (1999) (6)
Drug Transport in the Kidney (2014) (6)
L-type amino acid transporter 1 (LAT1)-specific inhibitor is effective against T cell-mediated nasal hyperresponsiveness. (2020) (5)
Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells (2018) (5)
Evidence that alpha-1-adrenergic stimuli specifically increase gluconeogenesis of the isolated proximal convoluted tubule in the rat. (1986) (5)
Positive correlation of expression of L-type amino-acid transporter 1 with colorectal tumor progression and prognosis: Higher expression in sporadic colorectal tumors compared with ulcerative colitis-associated neoplasia. (2020) (5)
Distinct interleukin-1beta-converting enzyme family proteases mediate cisplatin- and staurosporine-induced apoptosis of mouse proximal tubule cells. (1998) (5)
Differential effects of DNA tumor virus genes on the expression profiles, differentiation, and morphogenetic reprogramming potential of epithelial cells. (2002) (5)
Heterogeneity of Nephron Energy Metabolism: Implications for Response to Hypoxic Insult (1991) (5)
Developing selective L-Amino Acid Transport 1 (LAT1) inhibitors: A Structure-Activity Relationship overview (2019) (5)
The Acute Encephalopathy Induced by Intake of Sugihiratake Mushroom in the Patients with Renal Damage Might Be Associated with the Intoxication of Cyanide and Thiocyanate (2015) (5)
Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (5)
[Amino acid transporter molecule as a drug target]. (1999) (5)
Localization of 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the mammalian kidney. (1980) (5)
Postnatal development of urea concentration in the newborn rabbit's kidney. (1971) (4)
Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. (2021) (4)
Corrigendum to “Interaction of human organic anion transporters with various cephalosporin antibiotics” [Eur. J. Pharmacol. 438 (2001) 137–142] (2002) (4)
Functional expression of the rat organic anion transporter 1 (rOAT1) in Saccharomyces cerevisiae. (2005) (4)
Nephrotoxicity of cisplatin in rats. (1986) (4)
Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer (2020) (4)
Establishment of a mouse macula densa cell line with an nNOS promoter driving EGFP expression. (2005) (4)
Functional Analysis of Human Sodium-Phosphate Transporter 4 (NPT4/SLC17A3) Polymorphisms. (2011) (4)
Analysis of uric acid transport via hOAT3. (2000) (4)
L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation (2021) (4)
Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture. (2006) (4)
Attenuation of renomedullary phospholipase C isozyme, PLC‐δ1, in spontaneously hypertensive rats (1997) (4)
Potassium-Retaining Diuretics: Aldosterone Antagonists (1995) (4)
EZH2 Inhibitor GSK126: Metabolism, drug transporter and rat pharmacokinetic studies (2015) (4)
Primary Metabolic and Renal Hyperuricemia (2009) (4)
[Molecular mechanisms of drug transport]. (2000) (4)
Contribution of purine nucleotide cycle to intranephron ammoniagenesis in rats. (1988) (4)
Evidence suggesting a role for phospholipase C isozyme, PLC-delta 1 in corticomedullary osmotic gradients in rat kidneys. (1995) (4)
Chapter 4 – Renal Basis of Hyperuricemia (2012) (4)
[Urate transporter and renal hypouricemia]. (2003) (3)
Intranephron distribution of creatine content in rats. (1994) (3)
Renal gluconeogenesis in man: comparison with rats and rabbits. (1994) (3)
Intra- and inter-nephron heterogeneity of gluconeogenesis in the rat: effects of chronic metabolic acidosis and potassium depletion (2004) (3)
Cyclic AMP-dependent protein kinase activity and endogenous protein phosphorylation in isolated cortical segments of rabbit nephron. (1982) (3)
Development of the alternative method for renal drug excretion using Xenopus oocyte expression system combined with a high throughput method, OOCYTEXPRESS ® (2008) (3)
Orotic acid transport via organic anion transporters OATs. (2008) (3)
Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma. (2017) (3)
Intranephron ammoniagenesis and its regulation by PGE2 in rats and mice. (1988) (3)
Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney (2020) (3)
INTRANEPHRON DISTRIBUTION AND PROPERTIES OF XANTHINE OXIDASE, SUPEROXIDE DISMUTASE AND GUANASE ACTIVITIES IN CONTROL AND NEPHROTIC RATS (1987) (3)
Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin’s lymphoma (2021) (2)
Mutations in renal drug efflux transporter hOATv1 cause hyperuricemia (2010) (2)
Intranephron distribution of epidermal growth factor immunoreactivity in the mouse. (1987) (2)
A two-site solid phase enzyme immunoassay for rat epidermal growth factor. (1988) (2)
Localization and properties of NAD-dependent 15 hydroxyprostaglandin dehydrogenase activity in spontaneously hypertensive rat kidney. (1986) (2)
Characterization of Human Orgnic Anion Transporter 4 (hOAT4) as a Low Affinity p-aminohippurate (PAH) Transporter (2007) (2)
A new approach for assessment of narcotic physical dependence using urinary sex-dependent low molecular weight proteins in male rats. (1983) (2)
Attenuation of renomedullary phospholipase C isozyme, PLC-delta 1, in spontaneously hypertensive rats. (1997) (2)
Cyclosporine Induces Apoptosis of Mouse Terminal Proximal Straight Tubule Cells (1998) (2)
[The mechanisms of urate transport in the kidney and the intestine]. (1996) (2)
[The pharmacogenomics of drug transporters: functional analysis approaches]. (2004) (2)
Mouse Asc-1 (asc-type amino acid transporter 1) maps to chromosome 7, region B1-B5 (2004) (2)
A novel Na(+)-dependent amino acid transporter with a high affinity to glutamine. (1997) (2)
Cellular adenosine triphosphate production and consumption in the descending thin limb of Henle's loop in the rat. (1990) (2)
Relationship between L-alanine and sodium ion transport in isolated renal tubules. (1975) (2)
Functional heterogeneity of rat hepatocytes: predominance of aryl hydrocarbon hydroxylase activity in perivenular zone. (1988) (2)
Inhibition of gluconeogenesis in rat renal cortex slices by metabolites of L-tryptophan in vitro (2004) (1)
Distribution and Possible Functions of γ -Glutamyl-Transpeptidase in the Kidney (第23回日本腎臓学会総会 ) -- (ネフロンのheterogeneity(シンポジウム-3-)) (1981) (1)
Primary Renal Uricosuria (2009) (1)
Differential expression of system L amino acid transporters during wound healing process in the skin of young and old rats. (2008) (1)
The identification and structural characterization of C7orf24 as γ-glutamyl cyclotransferase. An essential enzyme in the γ-glutamyl cycle. VOLUME 283 (2008) PAGES 22031-22042 (2008) (1)
V1a receptor mRNA expression in mouse early proximal tubule (S1) cell line is regulated by protein kinase A (1998) (1)
Renal Organic Solute Transporters: Relation to Serum (2010) (1)
Identification of the multivalent PDZ domain protein PDZK1 as a binding partner of sodium‐coupled monocarboxylate cotransporter 2 (SMCT2) by yeast two‐hybrid assay (2008) (1)
Interaction of a novel urate efflux transporter URATv1 (SLC2A9) with uricosuric agents. (2009) (1)
Species differences in cellular adenosine triphosphate turnover within the nephron. (1991) (1)
Endothelin receptor subtypes in rat kidney epithelial cells (1992) (1)
Increased expression of the amino acid transporter LAT1 during healing of acetic acid-induced chronic gastric ulcers in rats (2006) (1)
Renal Organic Solute Transporters: Relation to Serum Urate Disorder (2010) (1)
Preferential Expression of L‐type Amino Acid Transporter 1 in Ameloblasts During Rat Tooth Development (2004) (1)
[Drug-induced nephrotoxicity]. (1996) (1)
CHAPTER 7 – Solute Transport, Energy Consumption, and Production in the Kidney (2008) (1)
Mechanism of Ochratoxin A induced Nephropathy (1984) (1)
Angiotensin II receptor subtypes in rat early proximal tubule. (1991) (1)
High affinity D- and L-serine transporter Asc-1: Cloning and dendritic localization in the rat brain. (2004) (1)
Treatment effects and predictors of a 24‐week course of interferon α‐2b plus ribavirin combination therapy for patients with chronic hepatitis C (2006) (1)
Guanidinoacetic acid (GAA) synthesis in rat tubular suspension as a system for evaluating gentamicin (GM) nephrotoxicity. (1995) (1)
[Molecular biology of urate transporter]. (2004) (1)
Urinary sex-dependent low molecular weight proteins as a sign of narcotic dependence in male rats. (1983) (1)
Cell type-speciﬁc activation of metabolism reveals that (cid:1) -cell secretion suppresses glucagon release from (cid:2) -cells in rat pancreatic islets (2005) (0)
S1-4 Molecular Mechanisms of Permeation of Methylmercury through the Blood-Tissue Barriers.(Proceedings of the 27th Annual Meeting) (2000) (0)
Subject Index, Vol. 12, 1989 (2004) (0)
LAT 1 Is a Central Transporter of Essential Amino Acids in Human Umbilical Vein Endothelial Cells (2014) (0)
Effects of cephaloridine (CER) on mouse terminal proximal straight tubule (S_3) cell lines expressing rat and human organic anion transporter-1 (OAT1) (1998) (0)
The role of amino acid transporters in the cytotoxicity of methylmercury.(GENERAL SESSION BY POSTER PRESENTATION)(ENVIRONMENTAL CHEMICALS,HEAVY METALS & CYTOTOXICITY) (2002) (0)
Nouvel anticorps anti-cd98 (2007) (0)
Changes in protein excretion from rat kidney during administration of Angiotensin II and its analogues (1978) (0)
Effect of deoxycorticosterone acetate on ammoniagenesis in isolated nephron segments of rats (1984) (0)
Effects of MK 870 and Pteridine Derivatives on the Toad Bladder (1968) (0)
EFFECTS OF MERCURY ON THE STRUCTURAL PROTEINS OF VARIOUS SEGMENTS IN ISOLATED NEPHRON (The Fourth Meeting for the Study of Toxic Effect) (1977) (0)
Cis-platinum(II)-diamino dichloride(CDDP) induced toxicity in immortalized cell lines established from each nephron segment of transgenic mice harboring ts-SV40 T-antigen gene. (1993) (0)
215. TOXIC ACTION OF HEAVY METALS. 2. ANALYSIS OF PROTEINURIA DUE TO MERCURY (The Third Meeting for the Study of Toxic Effect) (1977) (0)
Isoform Selectivity of 3125 I-Iodo-- Methyl-L-Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (0)
Gender differences in expression of rat renal OAT1 (2003) (0)
Sodium-dependent transport activity for l-DOPA in Xenopus laevis oocyte injected with polya+ RNA from rabbit intestinal epithelium (1998) (0)
Functional properties and distribution of expression of neutral amino acid transporters in the central nervous system (1997) (0)
Molecular mechanisms of drug transport (2000) (0)
MOUSE RST FACILITATES TRANSCELLULAR TRANSPORT OF ORGANIC ANIONS BY A COORDINATION OF BASOLATERAL ORGANIC ANIO N TRANSPORTERS (OAT3 ) (2004) (0)
Human Nramp2 as a cadmium transporter.(GENERAL SESSION BY POSTER PRESENTATION)(ENVIRONMENTAL CHEMICALS,HEAVY METALS & CYTOTOXICITY) (2002) (0)
Targeting leukemia metabolism or essential amino acid uptake shows anti-tumoral activity in PTEN-deficient T-cell mouse lymphomas and T-ALL/T-LL human cells (2014) (0)
Characteristics of the isolated kidney cell recognized specifically with the monoclonal antibody (γG6) (1983) (0)
W2-1 SIGNIFICANCE OF ALTERNATIVE TOXICITY TESTING (1989) (0)
Attenuation of response to ANG II in adult spontaneously hypertensive rats kidney (1996) (0)
C-17 IDENTIFICATION OF A NOVEL LIVER SPECIFIC ORGANIC ANION TRANSPORTER SELECTIVE FOR CONJUGATED DRUGS AND STEROID HORMONES (2003) (0)
Cellular atp production and consumption in the descending thin limb of henle's loop in the rat (1990) (0)
21D-02-2 Involvement of Organic Anion Transporter1 (OAT1) in the Development of Renal Toxicity Related to Anionic Substances. (1999) (0)
P7-56 Identification of novel system L transporters and their methyl mercury-cysteine conjugates transport properties(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting) (2004) (0)
Pharmacological inhibition of the amino-acid transporter LAT1 demonstrates in vitro anti-neoplastic activity towards medulloblastoma (2018) (0)
RELATIONSHIP BETWEEN γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY IN URINE AND RENAL PROXIMAL TUBULAR DAMAGE(S) BY NEPHROTOXIC AGENTS (The 6th Meeting for the Study of Toxic Effect) (1979) (0)
Induction of rat hepatic CYP 1A1, 1B1, and AhR by 7, 12-dimethylbenz[α]anthracene on prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Drug metabolism, Proceedings of the 32nd Annual Meeting) (2005) (0)
Human Drug Transporter Gene-expressing Cells are Useful Alternatives to Predict Pharmacokinetics in Man (2011) (0)
Neutral amino acids transporter and corresponding gen (1999) (0)
Intranephron localization of 15-hydroxyprostaglandin dehydrogenase in the rat. (1983) (0)
Endothelin Increases Intracellular Free Calcium in Isolated Rat Nephron (1997) (0)
Identification and functional characterization of a novel cationic amino acid transporter CAT5 specifically expressed in placenta (2006) (0)
Amino Acids for Immune Reactions in LAT1 Is a Critical Transporter of Essential (2013) (0)
S1-2 Role of drug transporters in druginduced nephrotoxicity(Proceedings of the 27th Annual Meeting) (2000) (0)
Organic anion transporter 4 (OAT4) interacts with two PDZ Domain Proteins (2005) (0)
Method of Ultramicro-Analysis of Proteins Using 1-Dimethylamino-Naphthalene-5-Sulfonyl Chloride (DNS-CL) (1972) (0)
Evaluation of testicular toxicology in puberty to adult rats with prenatal exposure for 3, 3', 4, 4', 5-pentachlorobiphenyl(Proceedings of the 32nd Annual Meeting) (2005) (0)
The Increasing Effect of Bee-Venom on the Sodium Transport of the Toad Bladder (1968) (0)
新規尿酸トランスポーターURATv1(SLC2A9)遺伝子変異と腎性低尿酸血症 (2009) (0)
Acid-base, nephrolithiasis and divalent ions (2009) (0)
[Micromethods for the determination of metabolic characteristics in individual nephron segments]. (1994) (0)
Characterization of alpha-fetoprotein secreted from cultured reuber H-35 hepatoma cells (1982) (0)
H2O2-induced apoptosis In mouse proximal straight tubule (S3) cell line (II) (1996) (0)
L-TYPE AMINO ACID TRANSPORTER 1 EXPRESSION IN PROSTATE CANCER: ASSOCIATION WITH CANCER PROGRESSION AND HIGH-GRADE MALIGNANCY (2008) (0)
Silica increases cytosolic calcium and causes cell injury in renal cell lines. (1999) (0)
Direct Effect of Tetragastrin, Caerulein and Pancreozymin on the Enzyme Secretion of the Rabbit Pancreas (1972) (0)
Role of the inhibitory effect of tetrodotoxin on the active sodium transport of the toad bladder (2004) (0)
Kidney-specific urate transporter and its gen (2002) (0)
Preventive and therapeutic agent against phosphorus disorder, oral agent for the adsorption of phosphate ions in foods, beverages and chemical and manufacturing processes (2006) (0)
Functional characterization of a novel urate efflux transporter URATv1 (SLC2A9) and its relation to renal hypouricemia. (2009) (0)
Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation. (2021) (0)
Interaction of the multivalent PDZ domain protein PDZK1 with novel liver‐specific organic anion transporter 7 (OAT7) (2008) (0)
The A BC o f S olute C arriers (2004) (0)
Pathophysiological role of a Novel Vasopressin Receptor (Vp) in isolated SHRSP nephron segments (1992) (0)
[Relationship between the decrease in urinary sex-dependent low molecular weight proteins by morphine and hormonal parameters in male rats]. (1983) (0)
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1 (2022) (0)
Effects of 3-methylcholanthrene and starvation on intranephron distribution of cytochrome P-450. (1983) (0)
Expression of a system L amino acid transporter at testis of rats after prenatal exposure to di(n-butyl)phate(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting) (2005) (0)
A TSUSHI ENOMOTO,*t MICHIO TAKEDA, t AKIHI.RO TOJO,t T AKASHI SEKINE, t§ (2002) (0)
[Mechanism of renal transport of potassium]. (1981) (0)
Functional Characterization and Organic Anion Transporter Immunohistochemical 1 ( Slc 22 a 6 ) fromMouse Localization of Kidney (2014) (0)
Intranephron Distribution of Insulin Binding in Wistar Kyoto and Spontaneously Hypertensive Rats (1989) (0)
Functional Characterization and Immunohistochemical Localization of Organic Anion Transporter 1 (S1c22a6) from Mouse Kidney (2004) (0)
ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO (1986) (0)
MON-470 Pharmacological Inhibition of LAT1 Suppresses Proliferation and Hormone Synthesis in Rat Pituitary Tumor GH4 Cells [cc1] Synthesis May Be Better as Only mRNAs Were Measured (2019) (0)
Establishment of early proximal tubule (Si) cell line selectively expressing V1a receptor derived from transgenic mice harboring SV40 large T-antigen gene (1995) (0)
Relation between serum human albumin level and serum urate level in the chimeric mice having human hepatocytes. (2008) (0)
Transport of Methylmercury through the Epithelial Type Amino Acid Transporter System B0 (2019) (0)
Functional Analysis of Human Sodium-Phosphate Transporter 4 ( NPT 4 / SLC 17 A 3 ) Polymorphisms (2011) (0)
P-22 Protective effects of N-acetylcysteine, a precursor of glutathione, on teratogenicity of cadmium chloride in mice.(Proceedings of the 27th Annual Meeting) (2000) (0)
103. EFFECT OF MERCURY ON THE NEWT KIDNEY (The Second Meeting for the Study of Toxic Effect) (1976) (0)
Transport of nicotinate by human organic anion transporters of SLC22 family (2006) (0)
PCR cloning of Na+-dependent L-alanine transporter SNAT2(ASCT2B) gene from rat kidney. (1996) (0)
A new ultramicro analysis of protein by S.D.S. polyacrylamide gel electrophoresis. (1974) (0)
Investigation of expression of a system L neutral amino acid transporter LAT1 and its biological role in human glioma cells (2004) (0)
VECTORIAL TRANSPORT OF ORGANIC ANIONS ACROSS LLC-PK1 CELL MONOLAYERS (2004) (0)
Implications of free radicals for nephropathy and their scavenging agents. (1996) (0)
Drug transport studies by human MDR1 in Xenopus laevis oocyte expression system (2008) (0)
The multivalent PDZ domain protein PDZK1 upregulates the transport activity of renal urate-anion exchanger URAT1 via its C-terminal (2004) (0)
Expression of LAT1 predicts progression of transitional cell carcinoma of the upper urinary tract (2006) (0)
Current Status and Future Perspective on Molecular Toxicology (KEYNOTE LECTURE) (Proceedings of the 30th Annual Meeting) (2003) (0)
Distinct Interleukin-1β-converting enzyme (ICE) family proteases mediate cisplatin (CDDP)- and staurosporine (STS)- induced apoptosis of mouse terminal proximal tubule (S_3) cells (1998) (0)
Anti-tumor effects of L-type amino acid transporter 1 (LAT1) inhibitor in a syngeneic and orthotropic mouse model for melanoma (2019) (0)
Distribution and Properties of Intranephron Prostaglandin E2 Production in Wistar Kyoto and Stroke Prone Spontaneously Hypertensive Rats (1988) (0)
A NEW ULTRAMICRO ANALYSIS OF PROTEIN BY S.D.S.<SUP>1</SUP> POLYACRYLAMIDE GEL ELECTROPHORESIS (2006) (0)
Uricosuric agents and renal tubular transporters (2011) (0)
In vitro Thermoreversible Gel Disc Quantitative Assay of Rat Angiogenesis (2011) (0)
Progress in nephrotoxicology: from in vivo screening test to molecular mechanisms. (1998) (0)
Role of ammonium ion in adenosine triphosphate consumption of the rat medullary thick ascending limb. (1991) (0)
Partial purification of the antidiuretic hormone receptor from the rabbit kidney. (1983) (0)
Suppression of tumor angiogenesis by inhibition of LAT1 in stromal endothelial cells (2019) (0)
Transport of methylmercury through the epithelial type amino acid transport system B^0(Proceedings of the 32nd Annual Meeting) (2005) (0)
143 – EFFECTS OF ANGIOTENSIN IE AND ITS ANALOGUES ON PROTEINURIA IN RAT (1978) (0)
Suppressive effects of LAT1 specific inhibitor on allergic skin inflammation (2019) (0)
1126: A New Classification of Phenotype-Genotype of Cystinuria Patients in Japan (2004) (0)
PROGRESS INNEPHROTOXICOLOGY : TEST TO MOLECULAR FROM IN VIVO SCREENING MECHANISMS (2018) (0)
[Usefulness of microdissection of nephron segments and fluorescent indicator for molecular biological studies of nephron functions]. (1992) (0)
Organic anion transporter (OAT) family: the role as a drug transporter family (2000) (0)
Molecular aspects of the aldosterone effect on the developing rat kidney (1992) (0)
Narcotic physical dependence and urinary sex-dependent low molecular weight proteins in male rats. (1983) (0)
[Advances in the biochemical and immunohistochemical study of kidney tubule transport]. (1989) (0)
Roles of glutamate transporters in neuronal cell death (1994) (0)
Abstract 5286: Expression of cancer type amino acid transporter LAT1 is a prognosis prediction factor in breast carcinoma: comparison between triple-negative and non-triple-negative types (2015) (0)
Identification and Characterization of a Na 1 -independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral D - and L -Amino Acids* (2000) (0)
Micropuncture study of protein concentration in glomerular fluid in the newt. (1971) (0)
1125: Identification of A Novel Missense Mutation of SLC7A9 Frequent in Japanese Cystinuria Population that Cause Membrane Targeting Defect of the Transporter Protein by Introducing A Bulky Side Chain on its C -Terminus (2004) (0)
Functional characterization of urate transport via a novel urate efflux transporter URATv1. (2009) (0)
N-methyl-N-nitrosourea induced rat prostate carcinogenesis is modulated by prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Proceedings of the 32nd Annual Meeting) (2005) (0)
Human urate transporter 1 (URAT1) mediates orotic acid transport (2007) (0)
CBMS-05 COMPREHENSIVE METABOLOMIC ANALYSIS OF IDH1R132H CLINICAL GLIOMA SAMPLES REVEALS SUPPRESSION OF Β-OXIDATION DUE TO CARNITINE DEFICIENCY (2019) (0)
Agonists stimulated cAMP response in renal cell lines established from transgenic mice harboring SV40 large T antigen gene. (1994) (0)
Role of intracellular C‐terminal domain of the catalytic subunit of system b0,+ for its trafficking and the RACK1 binding. (2006) (0)
Acute renal failure - basic research (2009) (0)
[Organic ion transporter family]. (2001) (0)
Effects of aminonucleoside on renal function. (1972) (0)
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2. (1998) (0)
363 – GLUCOSE DEHYDROGENASE (HEXOSE 6-PHOSPHATE DEHYDROGENASE) AS SUPPLIER OF REDUCED PYRIDINE NUCLEOTIDES FOR MICROSOMAL ELECTRON TRANSPORT SYSTEM (1978) (0)
Use of hydantoin derivatives for the manufacture of a medicament for the treatment of diseases associated with active Sauestoff and free radicals (1996) (0)
[Identification of a novel urate transporter URAT1 and current status on urate research]. (2003) (0)
Transporter-mediated toxicity in the nephrotoxicity of organic compounds(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting) (2005) (0)
7th European Colloquium on Renal Physiology (Part 2 of 3) (1992) (0)
Erratum to “Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters” [Eur. J. Pharmacol. 419 (2001) 113–120] (2002) (0)
Pathophysiological Significance of a Novel Vasopressin Receptor (Vp) in Stroke-prone Spontaneously Hypertensive Rat Kidneys (1995) (0)
Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets. (2006) (0)
Functional characterization and tissue localization of a novel liver‐specific organic anion transporter OAT7 (2006) (0)
Contents, Vol. 12, 1989 (1989) (0)
7th European Colloquium on Renal Physiology (Part 1 of 3) (1992) (0)
Effect of Mercuric Chloride on Angiotensin II-Induced Ca ++ Transient in the Proximal Tubule of Rats (1991) (0)
A21 RELATIONSHIP BETWEEN CELLULAR ATP AND CYTOSOLIC CALCIUM IN NEPHROTOXIC MANIFESTATION (1989) (0)
Molecular identification of a novel prostaglandin‐specific organic anion transporter (OAT‐PG) that is colocalized with prostaglandin producing enzyme Cox‐2 in the distal tubular cells. (2006) (0)

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What Schools Are Affiliated With Hitoshi Endou?

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