Hitoshi Takahashi

Hitoshi Takahashi's AcademicInfluence.com Rankings

Hitoshi Takahashi

Biology

#10833

World Rank

#14191

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Neuroscience

#1711

World Rank

#1765

Historical Rank

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Biology

Hitoshi Takahashi's Degrees

Bachelors Biology University of Tokyo
PhD Neuroscience Stanford University

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Hitoshi Takahashi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

α-Synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy (1998) (523)
The Lewy body in Parkinson's disease: Molecules implicated in the formation and degradation of α‐synuclein aggregates (2007) (422)
Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription (2000) (413)
TDP‐43 mutation in familial amyotrophic lateral sclerosis (2008) (382)
Axonal α-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease (2008) (377)
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch (1998) (359)
Phosphorylated α-Synuclein Is Ubiquitinated in α-Synucleinopathy Lesions* (2002) (347)
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy (2015) (340)
Accumulation of α-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy (1998) (323)
NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease (1997) (322)
TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation (2007) (297)
The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders (2013) (292)
Synphilin‐1 is present in Lewy bodies in Parkinson's disease (2000) (277)
Degeneration of Cardiac Sympathetic Nerve Begins in the Early Disease Process of Parkinson’s Disease (2007) (252)
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans. (2011) (252)
Cardiac sympathetic denervation precedes neuronal loss in the sympathetic ganglia in Lewy body disease (2005) (251)
Mutations in COQ2 in familial and sporadic multiple-system atrophy. (2013) (246)
Animal model of axonal Guillain‐Barré syndrome induced by sensitization with GM1 ganglioside (2001) (239)
Regional specificity of alterations in NGF, BDNF and NT‐3 levels in Alzheimer's disease (1996) (227)
Neuropathology with Clinical Correlations of Sporadic Amyotrophic Lateral Sclerosis: 102 Autopsy Cases Examined Between 1962 and 2000 (2003) (221)
Selective Insolubility of α-Synuclein in Human Lewy Body Diseases Is Recapitulated in a Transgenic Mouse Model (2001) (219)
An autopsy case of autosomal‐recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene (2000) (212)
Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease. (2008) (207)
Animal model of axonal Guillain-Barré syndrome induced by sensitization with GM1 ganglioside. (2001) (195)
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy (2018) (193)
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster (2003) (193)
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions. (2002) (191)
Nuclear Accumulation of Truncated Atrophin-1 Fragments in a Transgenic Mouse Model of DRPLA (1999) (180)
Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease (1995) (180)
Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease Brains* (2009) (175)
Brain Cannabinoid CB2 Receptor in Schizophrenia (2010) (170)
Dentatorubral‐pallidoluysian atrophy: Clinical features are closely related to unstable expansions of trinucleotide (CAG) repeat (1995) (164)
Globular glial tauopathies (GGT): consensus recommendations (2013) (155)
Evaluation of changes in methylmercury accumulation in the developing rat brain and its effects: a study with consecutive and moderate dose exposure throughout gestation and lactation periods (2002) (153)
Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology (2011) (151)
Late‐onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation (2002) (148)
Cervical Spondylotic Myelopathy: Clinicopathologic Study on the Progression Pattern and Thin Myelinated Fibers of the Lesions of Seven Patients Examined During Complete Autopsy (1996) (147)
Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions (2008) (147)
Cellular pathology in multiple system atrophy (2006) (145)
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons (2012) (144)
Demonstration of α-Synuclein Immunoreactivity in Neuronal and Glial Cytoplasm in Normal Human Brain Tissue Using Proteinase K and Formic Acid Pretreatment (2002) (138)
ApoE–ε4 and early–onset Alzheimer's (1994) (137)
CAG repeat disorder models and human neuropathology: similarities and differences (2007) (137)
Spinocerebellar ataxia type 6: CAG repeat expansion in α1a voltage‐dependent calcium channel gene and clinical variations in japanese population (1997) (133)
Involvement of the peripheral nervous system in synucleinopathies, tauopathies and other neurodegenerative proteinopathies of the brain (2010) (128)
Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese. (2009) (127)
Patients with temporal lobe epilepsy show an increase in brain-derived neurotrophic factor protein and its correlation with neuropeptide Y (1999) (126)
Prefrontal Abnormality of Schizophrenia Revealed by DNA Microarray: Impact on Glial and Neurotrophic Gene Expression (2004) (121)
Patients homozygous and heterozygous for SNCA duplication in a family with parkinsonism and dementia. (2008) (121)
Selective reduction of a PDZ protein, SAP‐97, in the prefrontal cortex of patients with chronic schizophrenia (2002) (121)
Cerebellar involvement in progressive supranuclear palsy: A clinicopathological study (2009) (120)
Germ‐line and somatic mutations of the APC gene in patients with turcot syndrome and analysis of APC mutations in brain tumors (1994) (119)
Degeneration of cardiac sympathetic nerve can occur in multiple system atrophy (2006) (119)
A quantitative investigation of the substantia nigra in Huntington's disease (1989) (119)
Multiplex families with multiple system atrophy. (2007) (116)
Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice (2009) (116)
Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy. (2007) (115)
SCA17 homozygote showing Huntington's disease‐like phenotype (2004) (114)
Cognitive impairment and cortical degeneration in neuromyelitis optica (2013) (114)
Ultrastructural localization of CD38 immunoreactivity in rat brain (1997) (113)
Influences of dopaminergic lesion on epidermal growth factor‐ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons (2005) (110)
Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia (2008) (108)
Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. (2009) (107)
The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis (2012) (103)
Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly (2015) (103)
TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia (2007) (103)
Accumulation of phosphorylated α-synuclein in the brain and peripheral ganglia of patients with multiple system atrophy (2004) (101)
Hypertrophic pachymeningitis: significance of myeloperoxidase anti-neutrophil cytoplasmic antibody. (2014) (101)
Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS (2014) (100)
Analysis of the expression level of α-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy (2001) (99)
Widespread occurrence of intranuclear atrophin‐1 accumulation in the central nervous system neurons of patients with dentatorubral‐pallidoluysian atrophy (2001) (98)
Variants associated with Gaucher disease in multiple system atrophy (2015) (97)
Novel mutations, pseudo‐dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism (2000) (96)
Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease (2011) (96)
Characteristics of Aquaporin Expression Surrounding Senile Plaques and Cerebral Amyloid Angiopathy in Alzheimer Disease (2012) (92)
Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1. (2011) (91)
Preserved cardiac sympathetic nerve accounts for normal cardiac uptake of MIBG in PARK2 (2005) (88)
Pathology of CAG repeat diseases (2000) (87)
Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger–Huët anomaly (2010) (86)
Relationship Among &agr;-Synuclein Accumulation, Dopamine Synthesis, and Neurodegeneration in Parkinson Disease Substantia Nigra (2006) (86)
Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer’s disease☆ (1999) (85)
Immunocytochemical localization of synphilin-1, an α-synuclein-associated protein, in neurodegenerative disorders (2002) (85)
A mutant PSEN1 causes dementia with lewy bodies and variant Alzheimer's disease (2005) (84)
Aβ1–40 but not Aβ1–42 levels in cortex correlate with apolipoprotein E ϵ4 allele dosage in sporadic Alzheimer's disease (1997) (84)
Autophagic adapter protein NBR1 is localized in Lewy bodies and glial cytoplasmic inclusions and is involved in aggregate formation in α-synucleinopathy (2012) (82)
Bilateral periventricular nodular heterotopia due to filamin 1 gene mutation: widespread glomeruloid microvascular anomaly and dysplastic cytoarchitecture in the cerebral cortex (2002) (82)
TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies (2010) (82)
Clinical and neuropathological aspects of autosomal recessive juvenile parkinsonism (1998) (82)
Clinicopathological study of diffuse type brainstem gliomas: analysis of 40 autopsy cases. (2002) (80)
Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein (2004) (80)
Multiple system atrophy with severe involvement of the motor cortical areas and cerebral white matter (1998) (80)
Pathological heterogeneity in progressive supranuclear palsy and corticobasal degeneration (2004) (78)
Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72 (2012) (77)
Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis. (2013) (77)
Inhibition of VEGF signaling pathway attenuates hemorrhage after tPA treatment (2011) (77)
Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease. (2006) (76)
Co-localization of α-synuclein and phosphorylated tau in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration (2001) (75)
The intermediolateral nucleus and Clarke’s column in Parkinson’s disease (1997) (75)
Alteration of POLDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS (2012) (75)
Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum (1986) (74)
Genetic association study on in and around the APOE in late-onset Alzheimer disease (2009) (71)
Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice (2010) (69)
Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43 (2016) (68)
Immunohistochemical comparison of α- and β-synuclein in adult rat central nervous system (2002) (67)
Accumulation of phosphorylated alpha-synuclein in the brain and peripheral ganglia of patients with multiple system atrophy. (2004) (65)
NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1. (2006) (65)
Keap1 Is Localized in Neuronal and Glial Cytoplasmic Inclusions in Various Neurodegenerative Diseases (2013) (65)
α‐Synuclein Accumulates in Purkinje Cells in Lewy Body Disease but not in Multiple System Atrophy (2003) (64)
Subcellular localization of growth inhibitory factor in rat brain: light and electron microscopic immunohistochemical studies (1996) (64)
Dose-dependent effects of methylmercury administered during neonatal brain spurt in rats. (2004) (64)
Endothelin‐1 in the brain of patients with galactosialidosis: Its abnormal increase and distribution pattern (2000) (63)
Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population. (2014) (61)
Accumulation of histone deacetylase 6, an aggresome‐related protein, is specific to Lewy bodies and glial cytoplasmic inclusions (2011) (61)
A decrease in interleukin-1 receptor antagonist expression in the prefrontal cortex of schizophrenic patients (2003) (60)
Primary lateral sclerosis: a rare upper-motor-predominant form of amyotrophic lateral sclerosis often accompanied by frontotemporal lobar degeneration with ubiquitinated neuronal inclusions? (2003) (59)
Genetic association of CTNNA3 with late-onset Alzheimer's disease in females. (2007) (59)
No mutation in the entire coding region of the α-synuclein gene in pathologically confirmed cases of multiple system atrophy (1999) (58)
An Inducer of VGF Protects Cells against ER Stress-Induced Cell Death and Prolongs Survival in the Mutant SOD1 Animal Models of Familial ALS (2010) (57)
Neuropathology of sporadic amyotrophic lateral sclerosis of long duration (1997) (57)
Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology (2008) (56)
Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy (2016) (56)
Surgical Strategy and Outcomes for Epileptic Patients with Focal Cortical Dysplasia or Dysembryoplastic Neuroepithelial Tumor (2001) (56)
Microglial cystatin F expression is a sensitive indicator for ongoing demyelination with concurrent remyelination (2011) (56)
Accumulation of the sigma‐1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases (2014) (55)
p62/sequestosome 1 binds to TDP‐43 in brains with frontotemporal lobar degeneration with TDP‐43 inclusions (2012) (55)
Clinicopathological features in anterior visual pathway in neuromyelitis optica (2016) (55)
Widespread neuronal degeneration in rats following oral administration of methylmercury during the postnatal developing phase: a model of fetal-type Minamata disease (1998) (54)
α-Synuclein pathology in the neostriatum in Parkinson’s disease (2008) (54)
Intrauterine methylmercury intoxication Consequence of the inherent brain lesions and cognitive dysfunction in maturity (2000) (53)
Expression of α-synuclein, the precursor of non-amyloid β component of Alzheimer's disease amyloid, in human cerebral blood vessels (2002) (53)
Immunocytochemical localization of synaptic vesicle-specific protein in lewy body-containing neurons in Parkinson's disease (1992) (53)
Gene expression signature‐based prognostic risk score in patients with glioblastoma (2013) (53)
Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy (2014) (52)
Analysis of Chromosome 19q13.42 Amplification in Embryonal Brain Tumors with Ependymoblastic Multilayered Rosettes (2012) (52)
Alteration of autophagosomal proteins in the brain of multiple system atrophy (2013) (52)
Association of the HSPG2 Gene with Neuroleptic-Induced Tardive Dyskinesia (2010) (51)
Upregulation of α‐synuclein by lipopolysaccharide and interleukin‐1 in human macrophages (2002) (50)
Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity (2010) (50)
Coexistence of Huntington’s disease and amyotrophic lateral sclerosis: a clinicopathologic study (2012) (48)
Primary lateral sclerosis: Upper‐motor‐predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration – immunohistochemical and biochemical analyses of TDP‐43 (2012) (48)
Cerebellar cortical tau pathology in progressive supranuclear palsy and corticobasal degeneration (2002) (48)
Immunohistochemical comparison of alpha- and beta-synuclein in adult rat central nervous system. (2002) (48)
Proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase: a possible site of action of antiapoptotic drugs (2003) (48)
α-Synuclein pathology affecting Bergmann glia of the cerebellum in patients with α-synucleinopathies (2003) (47)
A subset of senile dementia with high incidence of the apolipoprotein E ϵ2 allele (1997) (47)
Quantitative correlation between cardiac MIBG uptake and remaining axons in the cardiac sympathetic nerve in Lewy body disease (2015) (46)
Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain (2014) (46)
Suprachiasmatic nucleus in a patient with multiple system atrophy with abnormal circadian rhythm of arginine-vasopressin secretion into plasma (1998) (46)
Immunohistochemical profiles of IDH1, MGMT and P53: Practical significance for prognostication of patients with diffuse gliomas (2015) (46)
Selective involvement of large neurons in the neostriatum of Alzheimer's disease and senile dementia: a morphometric investigation (1987) (46)
Primary central nervous system lymphomas and related diseases: Pathological characteristics and discussion of the differential diagnosis (2016) (45)
Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy (1998) (45)
The carboxy-terminal fragment of α1A calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells (2009) (45)
Induction of autophagy in temozolomide treated malignant gliomas (2011) (45)
Early clinical features of patients with progressive supranuclear palsy with predominant cerebellar ataxia. (2013) (45)
Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats (2004) (44)
Dementia and delirium in 4 patients with Machado-Joseph disease. (2002) (44)
Pathology and sensitivity of current clinical criteria in corticobasal syndrome (2014) (44)
Familial idiopathic basal ganglia calcification: Histopathologic features of an autopsied patient with an SLC20A2 mutation (2016) (43)
A quantitative study on the expression of synapsin II and N-ethylmaleimide-sensitive fusion protein in schizophrenic patients (2001) (43)
Autosomal dominant diffuse Lewy body disease (1998) (42)
Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy (2015) (41)
Correlative decrease of large neurons in the neostriatum and basal nucleus of Meynert in Alzheimer's disease (1989) (41)
Apolipoprotein E ε4 allele and progression of cortical Lewy body pathology in Parkinson’s disease (1998) (41)
Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice (2008) (41)
Characteristic microglial features in patients with hereditary diffuse leukoencephalopathy with spheroids (2016) (40)
Disclosure of a pro-apoptotic glyceraldehyde-3-phosphate dehydrogenase promoter: anti-dementia drugs depress its activation in apoptosis. (2004) (40)
Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado–Joseph disease (2009) (40)
Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury (2000) (39)
Assessment of copy number variations in the brain genome of schizophrenia patients (2015) (39)
Cardiac sympathetic denervation in Parkinson’s disease linked to SNCA duplication (2008) (39)
Clinical Aspects of ‘Senile Dementia of the Tangle Type’ – A Subset of Dementia in the Senium Separable from Late-Onset Alzheimer’s Disease (1998) (39)
Sporadic amyotrophic lateral sclerosis: Widespread multisystem degeneration with TDP‐43 pathology in a patient after long‐term survival on a respirator (2009) (39)
Restricted occurrence of Lewy bodies in the dorsal vagal nucleus in a patient with late-onset parkinsonism (1999) (39)
Activation of Signal Transducer and Activator of Transcription-3 in the Spinal Cord of Sporadic Amyotrophic Lateral Sclerosis Patients (2009) (39)
Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration? (2005) (38)
Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies (2004) (38)
Accumulation of phosphorylated α‐synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration (2016) (37)
Increased Levels of Soluble LR11 in Cerebrospinal Fluid of Patients with Alzheimer Disease (2010) (37)
Alteration of Upstream Autophagy‐Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease (2016) (37)
SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease. (2013) (37)
Alpha-synuclein accumulates in Purkinje cells in Lewy body disease but not in multiple system atrophy. (2003) (37)
Autophagy-related proteins (p62, NBR1 and LC3) in intranuclear inclusions in neurodegenerative diseases (2012) (37)
α-Synuclein immunoreactivity in normal and neoplastic Schwann cells (2002) (37)
Some glial progenitors in the neonatal subventricular zone migrate through the corpus callosum to the contralateral cerebral hemisphere (2003) (36)
Formation of granular cytoplasmic aggregates in COS7 cells expressing mutant Cu/Zn superoxide dismutase associated with familial amyotrophic lateral sclerosis (1998) (35)
Difference in MSA phenotype distribution between populations: genetics or environment? (2012) (35)
Neuronal migration disturbance and consequent cytoarchitecture in the cerebral cortex following transplacental administration of methylmercury (2002) (35)
Selective decrease of large neurons in the neostriatum in progressive supranuclear palsy (1988) (35)
Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes (2016) (35)
Ubiquilin immunoreactivity in cytoplasmic and nuclear inclusions in synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease (2012) (34)
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis (2015) (33)
Sporadic four-repeat tauopathy with frontotemporal degeneration, parkinsonism and motor neuron disease (2005) (33)
Biochemical and histopathological alterations in TAR DNA‐binding protein‐43 after acute ischemic stroke in rats (2011) (32)
Sporadic fatal insomnia with spongiform degeneration in the thalamus and widespread PrPSc deposits in the brain (2005) (32)
Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG) (2017) (32)
Large neurons in the neostriatum in Alzheimer's disease and progressive supranuclear palsy: a topographic, histologic and ultrastructural investigation (1991) (32)
Spinocerebellar ataxia type 2 (SCA2) is associated with TDP-43 pathology (2011) (32)
PARKINSONʼS DISEASE: AN IMMUNOHISTOCHEMICAL STUDY OF LEWY BODY-CONTAINING NEURONS IN THE ENTERIC NERVOUS SYSTEM (1989) (32)
Argyrophilic grains are reliable disease-specific features of corticobasal degeneration. (2014) (31)
Expression of ErbB4 in substantia nigra dopamine neurons of monkeys and humans (2009) (31)
Neuronal nuclear alterations in dentatorubral-pallidoluysian atrophy: ultrastructural and morphometric studies of the cerebellar granule cells (2001) (31)
Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington’s, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease (2012) (31)
Familial amyotrophic lateral sclerosis with bulbar onset and a novel Asp101Tyr Cu/Zn superoxide dismutase gene mutation (2004) (31)
Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene (2013) (30)
Intraventricular pleomorphic xanthoastrocytoma with anaplastic features (2009) (30)
Vertebral basilar system dolichoectasia with marked infiltration of IgG4‐containing plasma cells: A manifestation of IgG4‐related disease? (2012) (30)
Brain expression level and activity of HDAC6 protein in neurodegenerative dementia. (2013) (30)
Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation (2013) (30)
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy (2014) (30)
Widespread multiple system degeneration in a patient with familial amyotrophic lateral sclerosis (1993) (29)
Instability of mutant Cu/Zn superoxide dismutase (Ala4Thr) associated with familial amyotrophic lateral sclerosis (1996) (29)
Upregulation of alpha-synuclein by lipopolysaccharide and interleukin-1 in human macrophages. (2002) (29)
Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in Lewy bodies (2015) (29)
Intracranial malignant lymphomas: clinicopathological study of 26 autopsy cases (2006) (29)
Hemifacial spasm associated with an ependymal cyst in the cerebellopontine angle. Case report. (2002) (29)
Erratum to: “Intrauterine methylmercury intoxication. Consequence of the inherent brain lesions and cognitive dysfunction in maturity” [Brain Res. 877 (2000) 322–330] 1 1 PII of original article: S0006-8993(00)02717-7 (2000) (28)
Enhanced Accumulation of Phosphorylated α-Synuclein and Elevated β-Amyloid 42/40 Ratio Caused by Expression of the Presenilin-1 ΔT440 Mutant Associated with Familial Lewy Body Disease and Variant Alzheimer's Disease (2007) (28)
Direct, Ca2+-dependent Interaction between Tubulin and Synaptotagmin I (2002) (28)
PLA2G6 accumulates in Lewy bodies in PARK14 and idiopathic Parkinson's disease (2017) (28)
Remote astrocytic response of prefrontal cortex is caused by the lesions in the nucleus basalis of Meynert, but not in the ventral tegmental area (1992) (28)
Analysis of microRNA from archived formalin-fixed paraffin-embedded specimens of amyotrophic lateral sclerosis (2014) (28)
Tyrosine hydroxylase-immunoreactive intrinsic neurons in the Auerbach's and Meissner's plexuses of humans (1989) (28)
Gallyas-positive, tau-negative glial inclusions in Parkinson's disease midbrain (1996) (28)
Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin‐proteasome system, autophagy and aggresome formation (2012) (28)
Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease. (2007) (27)
PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex (2017) (27)
Organization of the human synphilin-1 gene, a candidate for Parkinson's disease (2000) (27)
Involvement of the γ‐Secretase‐Mediated EphA4 Signaling Pathway in Synaptic Pathogenesis of Alzheimer's Disease (2012) (27)
Association of SNPs linked to increased expression of SLC1A1 with schizophrenia (2012) (27)
Cerebral astroblastoma in an adult: An immunohistochemical, ultrastructural and genetic study (2013) (27)
Eosinophilic intranuclear inclusions in the hippocampal pyramidal neurons of a patient with amyotrophic lateral sclerosis (1997) (27)
Progressive multifocal leukoencephalopathy showing extensive spinal cord involvement in a patient with lymphocytopenia (2009) (27)
Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: With Special Reference to Astrocytic Tau Pathology (2016) (27)
Occurrence of GD3 ganglioside in reactive astrocytes — an immunocytochemical study in the rat brain (1994) (26)
TDP‐43 pathology in polyglutamine diseases: With reference to amyotrphic lateral sclerosis (2014) (26)
Immunohistochemical localization of NUB1, a synphilin-1-binding protein, in neurodegenerative disorders (2007) (26)
Polyglutamine disease: Recent advances in the neuropathology of dentatorubral‐pallidoluysian atrophy (2006) (26)
AMBRA1, a novel α‐synuclein‐binding protein, is implicated in the pathogenesis of multiple system atrophy (2018) (26)
ALS‐associated protein FIG4 is localized in Pick and Lewy bodies, and also neuronal nuclear inclusions, in polyglutamine and intranuclear inclusion body diseases (2014) (26)
Relationship between lobar intracerebral hemorrhage and leukoencephalopathy associated with cerebral amyloid angiopathy: Clinicopathological study of 64 Japanese patients (2003) (26)
Epstein‐Barr virus‐associated primary central nervous system cytotoxic T‐cell lymphoma (2013) (25)
Chordoid glioma of the third ventricle: A report of two cases, one with ultrastructural findings (2009) (25)
Supportive evidence for reduced expression of GNB1L in schizophrenia. (2010) (25)
Globular Glial Mixed Four Repeat Tau and TDP‐43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia (2016) (25)
A quantitative pathological investigation of the cervical cord, roots and ganglia after long-term amputation of the unilateral upper arm (2004) (25)
Involvement of lysosomes in the pathogenesis of CAG repeat diseases (2002) (25)
Alpha-synuclein pathology affecting Bergmann glia of the cerebellum in patients with alpha-synucleinopathies. (2003) (24)
Selective involvement of large motor neurons in the spinal cord of rats treated with methylmercury (1998) (24)
Decreased VEGFR2 expression and increased phosphorylated Akt1 in the prefrontal cortex of individuals with schizophrenia. (2016) (24)
Autosomal recessive spastic paraplegia with hypoplastic corpus callosum, multisystem degeneration and ubiquitinated eosinophilic granules (2000) (24)
Experimentally Induced Leptomeningeal Glioneuronal Heterotopia and Underlying Cortical Dysplasia of the Lateral Limbic Area in Rats Treated Transplacentally with Methylmercury (2001) (24)
Lung carcinoma metastasis presenting as a pineal region tumor (2003) (24)
The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS (2008) (24)
Familial amyotrophic lateral sclerosis with a mutation in the Cu/Zn superoxide dismutase gene (2004) (24)
Periventricular nodular heterotopia functionally couples with the overlying hippocampus (2012) (24)
GPNMB ameliorates mutant TDP‐43‐induced motor neuron cell death (2017) (24)
Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in α-synucleinopathy (2012) (23)
Cardiac sympathetic denervation in Lewy body disease (2006) (23)
Fusiform gyrus epilepsy: the use of ictal magnetoencephalography. Case report. (2002) (23)
Results of treatment of 112 cases of primary CNS lymphoma. (2008) (23)
Corticobasal degeneration with focal, massive tau accumulation in the subcortical white matter astrocytes (2006) (23)
Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy (2017) (23)
Sporadic motor neuron disease with severe sensory neuronopathy (1998) (22)
Ultrastructural Relationship between Lewy Bodies and Pale Bodies Studied in Locus Ceruleus Neurons of a Non‐Parkinsonian Patient (1994) (22)
Expression of alpha-synuclein, the precursor of non-amyloid beta component of Alzheimer's disease amyloid, in human cerebral blood vessels. (2002) (22)
Neuropathology of dentatorubropallidoluysian atrophy (1996) (22)
Is angiomatosis an intrinsic pathohistological feature of massive osteolysis? Report of an autopsy case and a review of the literature (2003) (22)
Increased expression and activation of cytosolic phospholipase A2 in the spinal cord of patients with sporadic amyotrophic lateral sclerosis (2010) (21)
Pathological involvement of the motor neuron system and hippocampal formation in motor neuron disease-inclusion dementia (2003) (21)
alpha-Synuclein pathology in the neostriatum in Parkinson's disease. (2008) (21)
Are Bunina Bodies of Endoplasmic Reticulum Origin? An Ultrastructural Study of Subthalamic Eosinophilic Inclusions in a Case of Atypical Motor Neuron Disease (1991) (21)
Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy‐related inflammation (2012) (21)
Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome (2008) (21)
Reduced brain‐derived neurotrophic factor (BDNF) mRNA expression and presence of BDNF‐immunoreactive granules in the spinocerebellar ataxia type 6 (SCA6) cerebellum (2012) (21)
Frontal anaplastic oligodendroglioma showing multi-organ metastases after a long clinical course. Case report. (2007) (21)
Neuronal atrophy and synaptic alteration in a mouse model of dentatorubral-pallidoluysian atrophy. (2006) (21)
Evidence for transneuronal degeneration in the spinal cord in man: a quantitative investigation of neurons in the intermediate zone after long-term amputation of the unilateral upper arm (2004) (20)
Valosin‐containing protein immunoreactivity in tauopathies, synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease (2013) (20)
Spinocerebellar Ataxia Type 17 (SCA17). (2018) (20)
Expression of β-synuclein in normal human astrocytes (2001) (20)
Neurocutaneous melanosis: surgical pathological features of an apparently hamartomatous lesion in the amygdala. (2010) (20)
DRPLA transgenic mouse substrains carrying single copy of full-length mutant human DRPLA gene with variable sizes of expanded CAG repeats exhibit CAG repeat length- and age-dependent changes in behavioral abnormalities and gene expression profiles (2012) (20)
Serial CT and MRI findings in a patient with isolated angiitis of the central nervous system associated with cerebral amyloid angiopathy (2002) (20)
Reciprocal accumulation of β-synuclein in α-synuclein lesions in multiple system atrophy (2003) (20)
Oligodendrocytic polyglutamine pathology in dentatorubral‐pallidoluysian atrophy (2002) (20)
Reliable diagnosis of IDH-mutant glioblastoma by 2-hydroxyglutarate detection: a study by 3-T magnetic resonance spectroscopy (2018) (19)
ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis (2013) (19)
Lewy bodies in the cerebellar dentate nucleus of a patient with Parkinson's disease (1994) (19)
A possible variant of neuro-Behçet disease presenting chronic progressive ataxia without mucocutaneo-ocular symptoms (2006) (19)
Protein‐bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase‐1 mutation‐associated familial amyotrophic lateral sclerosis and its transgenic mouse model (2007) (19)
The perivascular microenvironment in Epstein–Barr virus positive primary central nervous system lymphoma: The role of programmed cell death 1 and programmed cell death ligand 1 (2018) (18)
Synphilin-1-Binding Protein NUB1 is Colocalized With Nonfibrillar, Proteinase K-Resistant &agr;-Synuclein in Presynapses in Lewy Body Disease (2011) (18)
Pathologic features of dysplasia and accompanying alterations observed in surgical specimens from patients with intractable epilepsy. (2004) (18)
α‐Synuclein pathology in the cranial and spinal nerves in Lewy body disease (2016) (18)
Neuropathology Associated with Exposure to Different Concentrations and Species of Mercury: A Review of Autopsy Cases and the Literature. (2020) (18)
Dropped head syndrome in amyotrophic lateral sclerosis (2013) (18)
Pick's disease: alpha- and beta-synuclein-immunoreactive Pick bodies in the dentate gyrus. (2002) (18)
Spinal cord involvement of primary central nervous system lymphomas: Histopathological examination of 14 autopsy cases (2002) (17)
Alzheimer's disease: Report of two autopsy cases with a clinical diagnosis of corticobasal degeneration (2010) (17)
Venous congestive myelopathy: Three autopsy cases showing a variety of clinicopathologic features (2008) (17)
YOD1 attenuates neurogenic proteotoxicity through its deubiquitinating activity (2018) (17)
Glial clusters and perineuronal glial satellitosis in the basal ganglia of neurofibromatosis type 1 (2008) (16)
Histopathologic features of an autopsied patient with cerebral small vessel disease and a heterozygous HTRA1 mutation (2018) (16)
Cytoplasmic Location of α1A Voltage-Gated Calcium Channel C-Terminal Fragment (Cav2.1-CTF) Aggregate Is Sufficient to Cause Cell Death (2013) (16)
Alteration of mitochondrial protein PDHA1 in Lewy body disease and PARK14. (2017) (16)
Bunina bodies in motor and non‐motor neurons revisited: A pathological study of an ALS patient after long‐term survival on a respirator (2014) (16)
Ca2+‐permeable AMPA receptors associated with epileptogenesis of hypothalamic hamartoma (2017) (16)
Three‐Dimensional Anisotropy Contrast Periodically Rotated Overlapping Parallel Lines with Enhanced Reconstruction (3DAC PROPELLER) on a 3.0T System: A New Modality for Routine Clinical Neuroimaging (2006) (16)
Progressive myoclonus epilepsy: extraneuronal brown pigment deposition and system neurodegeneration in the brains of Japanese patients with novel SCARB2 mutations (2014) (16)
Phagocytized corpora amylacea as a histological hallmark of astrocytic injury in neuromyelitis optica (2012) (16)
The occurrence of catecholamine neurons in a parietal lobe ganglioglioma (1987) (16)
Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V) (2016) (16)
Giant cell reparative granuloma of the temporal bone: neuroradiological and immunohistochemical findings. (2002) (16)
A primary CNS lymphoma in spontaneous remission for 3.5 years after initial detection of the lesions by MRI (2006) (15)
Spatiotemporal dynamics of epileptiform propagations: Imaging of human brain slices (2011) (15)
Neurobehavioral deficits of epidermal growth factor-overexpressing transgenic mice: Impact on dopamine metabolism (2013) (15)
Similarities and differences among progressive among progressive supranuclear palsy, corticobasal degeneration and Pick's disease (1996) (15)
Suppressed Expression of Autophagosomal Protein LC3 in Cortical Tubers of Tuberous Sclerosis Complex (2013) (15)
Disruption of Postnatal Progenitor Migration and Consequent Abnormal Pattern of Glial Distribution in the Cerebrum Following Administration of Methylmercury (2003) (14)
Isolation and characterization of an N-linked oligosaccharide that is increased in glioblastoma tissue and cell lines. (2005) (14)
Cerebral lipoma and the underlying cortex of the temporal lobe: pathological features associated with the malformation (2005) (14)
Alterations of oligodendrocytes and demyelination in the spinal cord of patients with mitochondrial encephalomyopathy (1988) (14)
Involvement of Onuf’s nucleus in Machado–Joseph disease: a morphometric and immunohistochemical study (2010) (14)
Decreased cardiac uptake of MIBG is a potential biomarker for the presence of Lewy bodies (2007) (14)
Co‐localization of Bunina bodies and TDP‐43 inclusions in lower motor neurons in amyotrophic lateral sclerosis (2014) (14)
Pick's disease: α- and β-synuclein-immunoreactive Pick bodies in the dentate gyrus (2002) (14)
Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging (2018) (13)
Three-repeat Tau 69 is a major tau isoform in laser-microdissected Pick bodies (2006) (13)
Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism (2014) (13)
Familial amyotrophic lateral sclerosis: a SOD1-unrelated Japanese family of bulbar type with Bunina bodies and ubiquitin-positive skein-like inclusions in lower motor neurons (2007) (13)
Dysembryoplastic neuroepithelial tumor: report of a case without typical glioneuronal elements (2004) (13)
Venous congestive myelopathy of the cervical spinal cord: An autopsy case showing a rapidly progressive clinical course (2007) (13)
A fourth ventricle atypical teratoid/rhabdoid tumor in an infant (2006) (13)
Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy (2011) (13)
Persistent cleavage and nuclear translocation of apoptosis-inducing factor in motor neurons in the spinal cord of sporadic amyotrophic lateral sclerosis patients (2009) (13)
Marinesco‐Sjögren syndrome with atrophy of the brain stem tegmentum and dysplastic cytoarchitecture in the cerebral cortex (2008) (13)
Sporadic Creutzfeldt–Jakob Disease MM1+2C and MM1 are Identical in Transmission Properties (2016) (13)
A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time (2022) (13)
[Pathology of familial Parkinson's disease]. (2007) (12)
Is motor neuron disease‐inclusion dementia a forme fruste of amyotrophic lateral sclerosis with dementia? An autopsy case further supporting the disease concept (2005) (12)
Pathologic Features of Dysplasia and Accompanying Alterations Observed in Surgical Specimens From Patients With Intractable Epilepsy (2004) (12)
Spinal cord tau pathology in cervical spondylotic myelopathy (2008) (12)
A case of congenital supratentorial tumor: Atypical teratoid/rhabdoid tumor or primitive neuroectodermal tumor? (2007) (12)
Reciprocal accumulation of beta-synuclein in alpha-synuclein lesions in multiple system atrophy. (2003) (12)
Dynein and dynactin components modulate neurodegeneration induced by excitotoxicity (2012) (12)
A mouse model of adult-onset multiple system atrophy (2019) (12)
MicroRNA expression profiles of multiple system atrophy from formalin-fixed paraffin-embedded samples (2016) (12)
Neuronal differentiation associated with Gli3 expression predicts favorable outcome for patients with medulloblastoma (2014) (11)
Anterior striatum with dysmorphic neurons associated with the epileptogenesis of focal cortical dysplasia (2010) (11)
A fatal neuromuscular disease in an adult patient after poliomyelitis in early childhood: Consideration of the pathology of post‐polio syndrome (2013) (11)
Demonstration of ganglioside GD3 in human reactive astrocytes (1999) (11)
Pick’s disease: selective occurrence of apolipoprotein E-immunoreactive Pick bodies in the limbic system (1997) (11)
Anaplastic astrocytoma with angiocentric ependymal differentiation (2011) (11)
G protein‐coupled receptor 26 immunoreactivity in intranuclear inclusions associated with polyglutamine and intranuclear inclusion body diseases (2016) (11)
Lymphoplasmacyte‐rich meningioma: A convexity mass with regional enhancement in the adjacent brain parenchyma (2012) (11)
Nestin immunoreactivity of Purkinje cells in Creutzfeldt-Jakob disease (2006) (11)
Transcranial imaging of audiogenic epileptic foci in the cortex of DBA/2J mice (2006) (11)
Creutzfeldt‐Jakob disease with an M232R substitution: report of a patient showing slowly progressive disease with abundant plaque‐like PrP deposits in the cerebellum (2009) (11)
The subnucleus gelatinosus of the nucleus tractus solitarii is a catecholaminergic nucleus: Immunohistochemical and ultrastructural studies in the human fetal brain (1985) (11)
Clinical and imaging findings of progressive supranuclear palsy with predominant cerebellar ataxia (2016) (11)
A serial MRI study in a patient with progressive supranuclear palsy with cerebellar ataxia. (2012) (10)
Novel pathological abnormalities of deep brain structures including dysplastic neurons in anterior striatum associated with focal cortical dysplasia in epilepsy. (2012) (10)
Pathological Heterogeneity of the Precentral Gyrus in Pick’s Disease: A Study of 16 Autopsy Cases (2006) (10)
Immunohistochemical localization of exoribonucleases (DIS3L2 and XRN1) in intranuclear inclusion body disease (2018) (10)
Sortilin-related receptor CNS expressed 2 (SorCS2) is localized to Bunina bodies in amyotrophic lateral sclerosis (2015) (9)
Late relapse of primary central nervous system lymphoma (2017) (9)
Aprosencephaly: histopathological features of the rudimentary forebrain and retina (2001) (9)
Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia (2018) (9)
Survival motor neuron (SMN) protein in the spinal anterior horn cells of patients with sporadic amyotrophic lateral sclerosis (2011) (9)
Globular glial tauopathy Type II: Clinicopathological study of two autopsy cases (2019) (9)
Balloon cells in the dentate gyrus in hippocampal sclerosis associated with non-herpetic acute limbic encephalitis (2011) (9)
Novel eosinophilic intracytoplasmic inclusions in a meningioma (1993) (9)
Malignant peripheral nerve sheath tumor of the trigeminal nerve: Clinicopathologic features in a young adult patient (2012) (9)
An autopsy case of incipient Pick's disease: Immunohistochemical profile of early‐stage Pick body formation (2014) (9)
A case of lymphomatosis cerebri mimicking inflammatory diseases (2016) (9)
Occurrence of ganglioside GD3 in neoplastic astrocytes (1999) (9)
Phosphorylated NUB1 distinguishes α‐synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy (2019) (8)
Genotype‐phenotype correlation in CAG‐repeat diseases (2002) (8)
Lewy bodies in Betz cells of the motor cortex in a patient with Parkinson's disease (2003) (8)
Cerebral and spinal cord tanycytic ependymomas in a young adult with a mutation in the NF2 gene (2014) (8)
Radiation-Induced Glioblastoma Following Radiotherapy for Pituitary Adenomas: Marked Response to Chemotherapy (2013) (8)
Molecular characterization and gene disruption of a novel zinc‐finger protein, HIT‐4, expressed in rodent brain (2010) (8)
Degeneration of the synaptic boutons of parallel fibers in rats treated with methylmercury: Chronological observations (1996) (8)
Amyotrophic Lateral Sclerosis with Pallidonigroluysian Degeneration: A Clinicopathological Study (2019) (8)
Neuropathology Training Worldwide—Evolution and Comparisons (2014) (7)
Global democratic consensus on neuropathological disease criteria (2002) (7)
Tentorial cavernous angioma with profuse bleeding. Case report. (2009) (7)
Widespread ischemic brain lesions caused by vasculopathy associated with neurofibromatosis type 1 (2010) (7)
[Clinical aspects of the Niigata Minamata disease]. (2015) (7)
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy (2014) (7)
Enhancement of native and phosphorylated TDP‐43 immunoreactivity by proteinase K treatment following autoclave heating (2011) (7)
[A case of primary central nervous system malignant lymphoma developing from the optic chiasma and hypothalamus]. (2006) (7)
Co‐localization of β‐peptide and phosphorylated tau in astrocytes in a patient with corticobasal degeneration (2006) (7)
Hippocampal sclerosis in the parkinsonism‐dementia complex of Guam: quantitative examination of neurons, neurofibrillary tangles, and TDP‐43 immunoreactivity in CA1 (2015) (6)
Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy (2015) (6)
Cyclopia: histogenesis of the single optic nerve (1997) (6)
Progressive supranuclear palsy on Guam (2001) (6)
Oligodendroglioma (WHO grade I) in a young epilepsy patient: A specific entity lying within the spectrum of dysembryoplastic neuroepithelial tumor? (2013) (6)
Degeneration of spinal dorsal root ganglia in adult rats treated with methylmercury: Chronological observations on the cell bodies, centrally directed axons and presynaptic terminals (1997) (6)
Developmental profile of ganglioside GD3 in the central nervous system: an immunocytochemical study in the rat (1994) (6)
A newly discovered age-related synaptic change in the human locus ceruleus: morphometric and ultrastructural studies (1996) (6)
Guillain-Barré syndrome micking botulism (2001) (6)
A Fulminant Case of Granulomatosis with Polyangiitis with Meningeal and Parenchymal Involvement (2015) (6)
[A useful marker for differential diagnosis of Parkinson's disease--MIBG myocardial scintigraphy]. (2004) (6)
Glycogen synthase kinase‐3β phosphorylates synphilin‐1 in vitro (2003) (6)
[An autopsy case of systemic vasculitis associated with hepatitis C virus-related mixed cryoglobulinemia presenting severe peripheral neuropathy]. (2004) (6)
Indication of intraoperative immunohistochemistry for accurate pathological diagnosis of brain tumors (2011) (6)
An Autopsy Case of Atypical Motor Neuron Disease with Bunina Bodies in the Lower Motor and Subthalamic Neurons (1991) (5)
DRPLA: recent advances in research using transgenic mouse models. (2013) (5)
Extracerebral ectopic mass with huge cysts in the anterior cranial cavity (2003) (5)
Epidermoid cyst involving the medial temporal lobe: Surgical pathologic features of the epileptogenic lesion (2012) (5)
Expression of Ganglioside GD3 in Choroid Plexus (1994) (5)
Pursuit of the origin of the large myelinated fibers of the anterolateral funiculus in the spinal cord in humans in relation to the pathomechanism in amyotrophic lateral sclerosis (1999) (5)
EGFRvIII Is Expressed in Cellular Areas of Tumor in a Subset of Glioblastoma (2019) (5)
Immunocytochemical demonstration of IGF-II-like immunoreactivity in human paraganglioma of the craniocervical region (2004) (5)
Primary frontal‐lobe germinoma appearing as a large cyst (2003) (5)
Spinocerebellar ataxia type 17 (2012) (5)
Long‐term survivors of primary central nervous system lymphoma (2017) (4)
Pleomorphic xanthoastrocytoma: New ultrastructural observations (1995) (4)
GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma. (2020) (4)
[A case suspected of acute gas poisoning by carbon monoxide (CO), presenting with progressive diffuse leukoencephalopathy associated with marked brain edema]. (2002) (4)
Autopsy findings of a craniopharyngioma with a natural course over 60 years. (2004) (4)
Entrapment of the inferior horns of the lateral ventricle with enlargement of the bilateral choroid plexus (2014) (4)
[A case of solitary fibrous tumor in the cerebral convexity indicating its non-dural origin]. (2007) (4)
An autopsy case of dementia with Lewy bodies showing autonomic failure and dementia as the initial symptoms (2007) (4)
Genetic Variations and Neuropathologic Features of Patients with PRKN Mutations (2021) (4)
Significance of horizontal propagation of synchronized activities in human epileptic neocortex investigated by optical imaging and immunohistological study (2013) (4)
Familial amyotrophic lateral sclerosis with an I104F mutation in the SOD1 gene: Multisystem degeneration with neurofilamentous aggregates and SOD1 inclusions (2017) (4)
Glycogen synthase kinase-3beta phosphorylates synphilin-1 in vitro. (2003) (4)
Plasma matrix metalloproteinase‐3 correlates with the clinical severity in men with multiple system atrophy (2013) (3)
Multiple gas-forming brain microabscesses due to Klebsiella pneumoniae. (2006) (3)
Primary leptomeningeal meningiomatosis with widespread whorl formation (2006) (3)
C9ORF72 repeat‐associated non‐ATG‐translated polypeptides are distributed independently of TDP‐43 in a Japanese patient with c9ALS (2014) (3)
[Radiation-induced intracranial osteosarcoma after radiation for acute lymphocytic leukemia associated with Li-Fraumeni syndrome]. (2013) (3)
Progressive supranuclear palsy: Neuropathology of patients with a short disease duration due to unexpected death (2020) (3)
Transganglionic gracile response following limb amputation in man (2000) (3)
Fine structural study of a cerebral tumor characterized by a honeycomb appearance after a 20‐year post‐mortem interval (2006) (3)
A 64‐year‐old man presenting MRIs of expansive multiple high intensity areas in the cerebral white matter, cerebellum and brainstem (2007) (3)
Metastatic pineocytoma of the spinal cord after long‐term dormancy (1994) (3)
[Neuropathological similarities and differences between frontotemporal lobar degeneration with ubiquitin inclusions and amyotrophic lateral sclerosis with dementia]. (2009) (2)
Loss of Motor Neurons Innervating Cervical Muscles in Patients With Multiple System Atrophy and Dropped Head (2018) (2)
[Pathology of neurodegenerative diseases: with special reference to Parkinson's disease and amyotrophic lateral sclerosis]. (2002) (2)
[Oral cyclophosphamide therapy for multifocal fibrosclerosis with hypertrophic intracranial pachymeningitis]. (2006) (2)
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Effects of the −141C insertion/deletion polymorphism in the dopamine D2 receptor gene on the dopamine system in the striatum in patients with schizophrenia (2018) (2)
Cerebral amyloid angiopathy‐related leukoencephalopathy: Successful steroid treatment for neurological deficits and subcortical white matter lesions partly involving the cortical gray matter (2014) (2)
Elevation of EGR1/zif268, a Neural Activity Marker, in the Auditory Cortex of Patients with Schizophrenia and its Animal Model (2022) (2)
CORRELATIVE DECREASE OF LARGE NEURONS IN THE NEOSTRIATUM AND BASAL NUCLEUS OF MEYNERT IN ALZHEIMERʼS DISEASE: 106 (1989) (2)
[A case report of primary central nervous system lymphoma preceded by cerebral and cerebellar lesion diminishing spontaneously: consideration of two brain biopsy at the onset and after two years]. (2009) (2)
Spinocerebellar degeneration: Discrepancies between clinical and pathological diagnoses (2016) (2)
[FTLD/ALS as TDP-43 proteinopathies]. (2010) (2)
Autopsy case of primary central nervous system lymphoma with subacute mental deterioration and progressive white matter lesions in an elderly man (2003) (2)
RADIATION THERAPY OF PRIMARY MALIGNANT LYMPHOMA OF THE BRAIN (1990) (2)
Nonfunctional intra‐ and suprasellar tumor in a patient with visual disturbance and panhypopituitarism (2016) (2)
Coexistence of Creutzfeldt‐Jakob disease and senile dementia of the Alzheimer type (1995) (1)
VIRUS‐LIKE PARTICLES IN CULTURED C3H/St MOUSE CELLS TREATED WITH A CARCINOGENIC POLYCYCLIC HYDROCARBON (1986) (1)
Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation (2013) (1)
Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy (2014) (1)
The 25th Annual Meeting of the Japanese Society for Neuroimmunology (JSNI) (2014) (1)
CNS NEURONAL TUMORS: A STUDY OF 5 CASES WITH IMMUNOCYTOCHEMICAL NEUROENDOCRINE MARKERS AND IGF II (1989) (1)
Characteristic expression of p57/Kip2 in balloon cells in focal cortical dysplasia (2015) (1)
Clinicopathologic Features of Two Patients With Sporadic Amyotrophic Lateral Sclerosis Who Maintained Communication Ability for Over 30 Years (2018) (1)
Parkinson's disease and parkinsonism: Clinicopathological discrepancies on diagnosis in three patients (2021) (1)
Adrenoleukodystrophy with involvement of the cerebral cortex (1997) (1)
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Clinical and pathological features affecting cardiac sympathetic denervation in autopsy‐confirmed dementia with Lewy bodies (2020) (1)
α-Synuclein, synphilin-1 and inclusion body formation in α-synucleinopathies (2003) (1)
Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes (2016) (0)
O-22-325 Clinicopathological study of 26 autopsy cases with intracranial malignant lymphomas (1997) (0)
Second Tumor Occurrence Following GH Treatment in Children with Brain Tumors: A Report of Two Cases (1997) (0)
Toxic , High Mass Amyloid Isolation and Characterization of Protein Structure and Folding : (2009) (0)
EGF Downregulates Presynaptic Maturation and Suppresses Synapse Formation In Vitro and In Vivo (2022) (0)
Widespread expression of α-synuclein in neuronal cytoplasm and glial cells in the central and peripheral nervous systems in human (2003) (0)
[Aberration of the spliceosome in amyotrophic lateral sclerosis]. (2014) (0)
Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy (2015) (0)
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Prognostic significance of S-phase fractions in peritumoral invading zone analyzed by laser scanning cytometry in patients with high-grade glioma: A preliminary study. (2016) (0)
Table 1. [Summary of Molecular Genetic Testing Used in Spinocerebellar Ataxia Type 17]. (2012) (0)
Reciprocal accumulation of &bgr;-synuclein in &agr;-synuclein lesions in multiple system atrophy (2003) (0)
Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V) (2016) (0)
[Neuropathological features in corticobasal degeneration and progressive supranuclear palsy]. (2002) (0)
P3-243: Gene expression profiling of postmortem brain tissues affected by Alzheimer's disease (2008) (0)
Early Clinical Features in Japanese Patients with Pathologically Proven Progressive Supranuclear Palsy with Cerebellar Ataxia (P04.163) (2013) (0)
Expression of α- and β-synucleins in cultured astrocytes and the effects of inflammatory cytokines (2003) (0)
Comprehensive cross-platform gene expression profiling analysis of dentatorubral-pallidoluysian atrophy (DRPLA) transgenic mice (2007) (0)
Clinicopathologic Analysis of TDP-43 Expression in the Cerebral Cortex in ALS (P1.077) (2014) (0)
Clinicopathological Analysis of Japanese Patients with Corticobasal Syndrome (P01.217) (2012) (0)
Establishment of pathology center for amyotrophic lateral sclerosis/Parkinson's disease complex in Kii Peninsula (2012) (0)
co-existence of Mm1 and Mm2 features in a Cjd presenting with rapidly progressive dementia : P-2-e03 (2012) (0)
GENES ASSOCIATED WITH THE PROGRESSION OF NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE BRAINS (2014) (0)
Basal ganglion hamartoma in a patient presenting with precocious puberty (2005) (0)
10. Morphological characteristic of spike sources from an epileptogenic region in ictal magnetoencephalography (2011) (0)
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy (2018) (0)
Disequilibrium in MSA phenotype distribution between populations: genetics or environment? (2010) (0)
2017 Japanese Neuropathology Prizes (2017) (0)
Table 2. [Frequency of Clinical Features in SCA17 Correlated with Repeat Size]. (2012) (0)
Involvement of EphA4/γ-secretase signaling in pathogenesis of Alzheimer's disease (2011) (0)
POSSIBLE HUMAN-TO-HUMAN TRANSMISSION OF CEREBRAL β-AMYLOIDOSIS VIA CADAVERIC DURA MATER GRAFTING (2017) (0)
Hereditary Diffuse Leukoencephalopathy With Spheroids (HDLS): Histological Features Of Microglia (P1.245) (2014) (0)
Figure 1. [Number of CAG/CAA repeats versus age of individuals with SCA17]. (2012) (0)
Accumulation of presynaptic proteinase K-resistant alpha-synuclein in Parkinson's disease (2010) (0)
Magnetoencepahlography-directed epilepsy surgery in children : Can invasive intracranial electrode monitoring be avoided ? (2008) (0)
PATH-54. Gli3 INDUCES NEURONAL DIFFERENTIATION IN WNT- AND SHH- ACTIVATED MEDULLOBLASTOMA (2017) (0)
The Role of NEDD8 Ultimate Buster 1, NUB1, in Neurodegenerative α-Synucleinopathies [Emerging Theories of Host Defense. The 10th Meeting Hirosaki International Forum of Medical Science. Communication Center Hirosaki University School of Medicine. Hirosaki on November 21-22, 2006] (2007) (0)
Analysis of microRNA from archived formalin-fixed paraffin-embedded specimens of amyotrophic lateral sclerosis (2014) (0)
Evidence of impaired macroautophagy in human degenerative cervical myelopathy (2022) (0)
[Clinical and pathological spectrum of TDP-43 associated ALS]. (2010) (0)
Decreased cardiac uptake of MIBG due to cardiac sympathetic denervation in Lewy body disease (2005) (0)
SORL1 JAD Wen Y et al Supple 2013 (2014) (0)
Globular Glial Tauopathy (GGT): clinical-pathological study of two autopsied cases and review of the literature (P2.090) (2017) (0)
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Figure 3. [Correlation in SCA17 between age at onset and length of CAG/CAA repeat]. (2012) (0)
Hereditary Diffuse Leukoencephalopathy with Spheroids (HDLS): Clinical Characteristics and Molecular Analyses of CSF-1R (PD5.009) (2013) (0)
Neuroblastoma ampliﬁed sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger e Hue¨t anomaly (0)
JAD140225 Miyashita TREM2 14-0225r1 140310 (2014) (0)
Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain (2014) (0)
Legends Suppl Tables (2014) (0)
EGF Downregulates Presynaptic Maturation and Suppresses Synapse Formation In Vitro and In Vivo (2022) (0)
Separate CNS lesions involving the brainstem and spinal cord in a 47‐year‐old man (2008) (0)
Phenotypic expression of transmitter receptors regulated by neurotrophic factors (1998) (0)
Role of meningeal lymphoid follicle-like structures in the CNS inflammatory disorders (2014) (0)
A Case of Chondroblastoma arising from the Convexity of the Frontal Bone (2006) (0)
Reciprocal accumulation of b-synuclein in a-synuclein lesions in multiple system atrophy (2003) (0)
In what direction, or under what laws, does the myelin wrap around the axon? (2004) (0)
Evidence of impaired macroautophagy in human degenerative cervical myelopathy (2022) (0)
2015 Japanese Neuropathology Prizes (2015) (0)
Gene expression profiling of postmortem brain tissues with Alzheimer's disease (2010) (0)
Myoclonus epilepsy, Anraku type(Hereditary Spinocerebellar Degeneration : recent advances) (1986) (0)
Selective cauda equina hypertrophy with idiopathic inflammation (2008) (0)
[Neuropathology of polyglutamine diseases]. (2003) (0)
The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders (2012) (0)
Non‐motor Neuron System in Amyotrophic Lateral Sclerosis: Involvement of Clarke's Column and Intermediolateral Nucleus (1993) (0)
Somatic Mosaicism ofExpanded CAG Repeats inBrains ofPatients withDentatorubral-Pallidoluysian Atrophy: Cellular Population- Dependent Dynamics ofMitotic Instability (1996) (0)
Large Neurons in the Neostriatum and Basal Nucleus of Meynert: Simultaneous Decrease in Alzheimer’s Disease (1990) (0)
[Human brain resource--experience at the Brain Research Institute,University of Niigata]. (2010) (0)
Assessment of copy number variations in the brain genome of schizophrenia patients (2015) (0)
Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid (cid:1) -Protein (A (cid:1) ) Assembly from Alzheimer Disease Brains (2009) (0)
Bunina body‐like eosinophilic intracytoplasmic inlusions in a gangliocytomatous brain lesion (1996) (0)
Nicotine receptor and amyloid burden for frontal activation in Alzheimer disease (0)

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What Schools Are Affiliated With Hitoshi Takahashi?

Hitoshi Takahashi is affiliated with the following schools:

Niigata University

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