Hjalte Rasmussen
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Why Is Hjalte Rasmussen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hjalte Rasmussen was Professor of European Union Law at the University of Copenhagen. Previously he was a Professor of law at the Law Department of the Copenhagen Business School and a Visiting Professor at the College of Europe, at Bruges.
Hjalte Rasmussen's Published Works
Published Works
- Regional Angiogenesis With Vascular Endothelial Growth Factor in Peripheral Arterial Disease: A Phase II Randomized, Double-Blind, Controlled Study of Adenoviral Delivery of Vascular Endothelial Growth Factor 121 in Patients With Disabling Intermittent Claudication (2003) (569)
- Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. (1997) (380)
- Sodium zirconium cyclosilicate in hyperkalemia. (2015) (359)
- Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial. (2014) (302)
- Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF121 (AdVEGF121) versus maximum medical treatment (2006) (264)
- Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer. (1998) (237)
- Combined analysis of studies of the effects of the matrix metalloproteinase inhibitor marimastat on serum tumor markers in advanced cancer: selection of a biologically active and tolerable dose for longer-term studies. (1998) (220)
- INTRAVENOUS MAGNESIUM IN ACUTE MYOCARDIAL INFARCTION (1986) (208)
- TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. (2004) (195)
- Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet: a randomized controlled trial. (2015) (188)
- Acute renal failure. Multivariate analysis of causes and risk factors. (1982) (180)
- Exaggeration of nonculprit stenosis severity during acute myocardial infarction: implications for immediate multivessel revascularization. (2002) (173)
- Reversible Oxidative Modification: A Key Mechanism of Na+-K+ Pump Regulation (2009) (162)
- Short-chain fatty acid production from mono- and disaccharides in a fecal incubation system: implications for colonic fermentation of dietary fiber in humans. (1988) (155)
- Maintenance of serum potassium with sodium zirconium cyclosilicate (ZS‐9) in heart failure patients: results from a phase 3 randomized, double‐blind, placebo‐controlled trial (2015) (137)
- Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions. (2002) (136)
- Characterization of Structure and Function of ZS-9, a K+ Selective Ion Trap (2014) (135)
- Field triage to primary angioplasty combined with emergency department bypass reduces treatment delays and is associated with improved outcome. (2007) (133)
- Degradation of amino acids to short-chain fatty acids in humans. An in vitro study. (1988) (128)
- Influence of magnesium substitution therapy on blood lipid composition in patients with ischemic heart disease. A double-blind, placebo controlled study. (1989) (127)
- A phase 2 study on the treatment of hyperkalemia in patients with chronic kidney disease suggests that the selective potassium trap, ZS-9, is safe and efficient (2015) (125)
- Prediction of outcome in acute renal failure by discriminant analysis of clinical variables. (1985) (115)
- Marimastat in patients with advanced pancreatic cancer: a dose-finding study. (1999) (110)
- Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis. (2020) (104)
- Magnesium deficiency in patients with ischemic heart disease with and without acute myocardial infarction uncovered by an intravenous loading test. (1988) (100)
- A Phase I Trial of TNFerade Biologic in Patients with Soft Tissue Sarcoma in the Extremities (2004) (93)
- Dofetilide, A Novel Class III Antiarrhythmic Agent (1992) (91)
- Regional Angiogenesis with Vascular Endothelial Growth Factor (VEGF) in peripheral arterial disease: Design of the RAVE trial. (2003) (90)
- TNFerade Biologic: Preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene (2002) (84)
- Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH oxidase. (2009) (83)
- Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy. (2002) (83)
- FXYD Proteins Reverse Inhibition of the Na+-K+ Pump Mediated by Glutathionylation of Its β1 Subunit* (2011) (82)
- Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. (2002) (82)
- &bgr;3 Adrenergic Stimulation of the Cardiac Na+-K+ Pump by Reversal of an Inhibitory Oxidative Modification (2010) (82)
- Magnesium infusion reduces the incidence of arrhythmias in acute myocardial infarction. A double‐blind placebo‐controlled study (1987) (79)
- Effects of the class III antiarrhythmic drug dofetilide on ventricular monophasic action potential duration and QT interval dispersion in stable angina pectoris. (1992) (78)
- Glutathionylation Mediates Angiotensin II–Induced eNOS Uncoupling, Amplifying NADPH Oxidase‐Dependent Endothelial Dysfunction (2014) (78)
- The electrophysiological effects of intravenous magnesium on human sinus node, atrioventricular node, atrium, and ventricle (1989) (76)
- Value of two-dimensional echocardiography, electrocardiography, and clinical signs in detecting right ventricular infarction. (1986) (74)
- Magnesium and acute myocardial infarction. Transient hypomagnesemia not induced by renal magnesium loss in patients with acute myocardial infarction. (1986) (74)
- Effect of osmotic swelling and shrinkage on Na(+)-K+ pump activity in mammalian cardiac myocytes. (1993) (72)
- Hyperaldosteronemia in rabbits inhibits the cardiac sarcolemmal Na(+)-K(+) pump. (2000) (71)
- Apical sparing in tako‐tsubo cardiomyopathy (2006) (71)
- Connections: heart disease, cellular electrophysiology, and ion channels (1992) (70)
- Efficacy and safety of a new selective class III antiarrhythmic agent dofetilide in paroxysmal atrial fibrillation or atrial flutter. (1992) (66)
- Pharmacokinetics and metabolism of dofetilide in mouse, rat, dog and man. (1992) (65)
- Angiotensin-converting enzyme inhibitors regulate the Na(+)-K+ pump via effects on angiotensin metabolism. (1996) (64)
- Adenoviral-mediated gene transfer of vascular endothelial growth factor in critical limb ischemia: safety results from a phase I trial (2003) (63)
- Na+ influx and Na(+)-K+ pump activation during short-term exposure of cardiac myocytes to aldosterone. (1998) (62)
- A randomized phase II pilot trial of adjuvant marimastat in patients with early-stage breast cancer. (2002) (60)
- Clinical and electrophysiologic effects of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with angina pectoris. (1992) (60)
- The first‐in‐man randomized trial of a beta3 adrenoceptor agonist in chronic heart failure: the BEAT‐HF trial (2017) (58)
- The nitric oxide donor sodium nitroprusside stimulates the Na+–K+ pump in isolated rabbit cardiac myocytes (2005) (58)
- Reversible oxidative modification: implications for cardiovascular physiology and pathophysiology. (2010) (58)
- Electrophysiologic profile and efficacy of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with sustained monomorphic ventricular tachycardia. Dofetilide Arrhythmia Study Group. (1995) (57)
- Angiotensin-converting enzyme inhibition, intracellular Na+, and Na(+)-K+ pumping in cardiac myocytes. (1995) (56)
- An in vitro study of short-chain fatty acid concentrations, production and absorption in pig (Sus scrofa) colon. (1992) (55)
- Activation of cAMP-dependent Signaling Induces Oxidative Modification of the Cardiac Na+-K+ Pump and Inhibits Its Activity* (2010) (54)
- Hemodynamic effects of intravenously administered magnesium on patients with ischemic heart disease (1988) (53)
- Prevalence of coronary occlusion and outcome of an immediate invasive strategy in suspected acute myocardial infarction with and without ST-segment elevation. (2002) (51)
- Myeloid progenitor cell proliferation and mobilization effects of BB10010, a genetically engineered variant of human macrophage inflammatory protein-1alpha, in a phase I clinical trial in patients with relapsed/refractory breast cancer. (1998) (50)
- Electrogenic Li+/Li+ exchange mediated by the Na+-K+ pump in rabbit cardiac myocytes. (1997) (50)
- Siglec-8 antibody reduces eosinophil and mast cell infiltration in a transgenic mouse model of eosinophilic gastroenteritis. (2019) (49)
- Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication. (2002) (49)
- Voltage-dependent stimulation of the Na(+)-K(+) pump by insulin in rabbit cardiac myocytes. (2000) (48)
- One‐year death rate in 270 patients with suspected acute myocardial infarction, initially treated with intravenous magnesium or placebo (1988) (48)
- Oxidative regulation of the Na(+)-K(+) pump in the cardiovascular system. (2012) (43)
- Susceptibility of β1 Na+-K+ Pump Subunit to Glutathionylation and Oxidative Inhibition Depends on Conformational State of Pump* (2012) (43)
- Mechanisms of Na+-K+pump regulation in cardiac myocytes during hyposmolar swelling. (1999) (42)
- Quantitative calculation of the role of the Na(+),K(+)-ATPase in thermogenesis. (2013) (42)
- Inhibition of Na‐K Pump Current in Guinea Pig Ventricular Myocytes by Dihydroouabain Occurs at High‐ and Low‐Affinity Sites (1989) (39)
- Serum methylmalonic acid in uraemia. (1992) (39)
- Pharmacokinetic and pharmacodynamic effects of UK-68,798, a new potential class III antiarrhythmic drug. (1991) (38)
- Amiodarone inhibits the Na(+)-K+ pump in rabbit cardiac myocytes after acute and chronic treatment. (1998) (35)
- Alloxan-induced diabetes reduces sarcolemmal Na+-K+ pump function in rabbit ventricular myocytes. (2007) (35)
- The influence of ispaghula husk and lactulose on the in vivo and the in vitro production capacity of short-chain fatty acids in humans. (1987) (35)
- The use of beta3-adrenergic receptor agonists in the treatment of heart failure. (2009) (34)
- Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes. (2008) (33)
- Effect of dofetilide on cardiac repolarization in patients with ventricular tachycardia. A study using simultaneous monophasic action potential recordings from two sites in the right ventricle. (1994) (33)
- Angiotensin regulates the selectivity of the Na+-K+ pump for intracellular Na. (1999) (32)
- HMG CoA reductase inhibition reduces sarcolemmal Na(+)-K(+) pump density. (2000) (31)
- Protein kinase Cɛ contributes to regulation of the sarcolemmal Na+-K+ pump (2001) (29)
- Natriuretic peptides stimulate the cardiac sodium pump via NPR-C-coupled NOS activation. (2008) (29)
- Two stable levels of diastolic potential at physiological K+ concentrations in human ventricular myocardial cells. (1990) (29)
- An Open-Label, Proof-of-Concept Study of Lirentelimab for Antihistamine-Resistant Chronic Spontaneous and Inducible Urticaria. (2021) (28)
- Inhibition of electrogenic Na(+)-pumping in isolated atrial tissue from patients treated with digoxin. (1990) (27)
- Lactulose detoxifies in vitro short-chain fatty acid production in colonic contents induced by blood: implications for hepatic coma. (1988) (27)
- VEGF gene therapy for coronary artery disease and peripheral vascular disease. (2002) (26)
- β3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade. (2015) (26)
- A dose-ranging study of UK-68,798, a novel class III anti-arrhythmic agent, in normal volunteers. (1991) (25)
- Dietary cholesterol affects Na+-K+ pump function in rabbit cardiac myocytes. (1997) (25)
- Redox-dependent regulation of the Na⁺-K⁺ pump: new twists to an old target for treatment of heart failure. (2013) (25)
- Sodium‐hydrogen exchange in guinea‐pig ventricular muscle during exposure to hyperosmolar solutions. (1991) (24)
- A Randomized, Double-Blind, Placebo-Controlled, Ascending Dose Phase 1 Study of AK002, a Novel Siglec-8 Selective Monoclonal Antibody, in Healthy Subjects (2018) (24)
- Dietary cholesterol alters Na+/K+ selectivity at intracellular Na+/K+ pump sites in cardiac myocytes. (2004) (23)
- Dependence of Na+-K+ pump current-voltage relationship on intracellular Na+, K+, and Cs+ in rabbit cardiac myocytes. (2002) (23)
- Protein kinase‐dependent oxidative regulation of the cardiac Na+–K+ pump: evidence from in vivo and in vitro modulation of cell signalling (2013) (21)
- New approaches to hyperkalemia in patients with indications for renin angiotensin aldosterone inhibitors: Considerations for trial design and regulatory approval. (2016) (21)
- Na+ influx and Na+-K+pump activation during short-term exposure of cardiac myocytes to aldosterone. (1998) (21)
- Regulation of intracellular pH in cardiac muscle during cell shrinkage and swelling in anisosmolar solutions. (1994) (20)
- Influence of oral magnesium supplementation on cardiac events among survivors of an acute myocardial infarction. (1993) (20)
- Short-chain fatty acids in bowel contents after intestinal surgery. (1989) (20)
- Identification of electric-field-dependent steps in the Na(+),K(+)-pump cycle. (2014) (19)
- Inhibition of electrogenic Na-pumping attributable to binding of cardiac steroids to high-affinity pump sites in human atrium. (1985) (18)
- Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition. (2015) (18)
- Multivariate Analysis of Causes and Risk Factors (1992) (17)
- The effect of intravenous magnesium therapy on serum and urine levels of potassium, calcium, and sodium in patients with ischemic heart disease, with and without acute myocardial infarction. (1988) (17)
- β-Adrenergic regulation of the cardiac Na+-K+ ATPase mediated by oxidative signaling. (2012) (17)
- Prediction of Outcome in Acute Renal Failure by Discriminant Analysis of Clinical Variables (1986) (16)
- Angiogenic gene therapy strategies for the treatment of cardiovascular disease. (2002) (16)
- Na+-dependent activation of Na+-K+ pump in human myocardium during recovery from acidosis. (1989) (16)
- A randomized phase II study of BB‐10010: a variant of human macrophage inflammatory protein‐1α for patients receiving high‐dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer (1997) (15)
- Natriuretic Peptides Stimulate the Cardiac Sodium Pump via NPR-C Coupled NOS Activation (2007) (14)
- New agents for hyperkalemia. (2015) (13)
- Myocardial contractility and performance capacity after magnesium infusions in young healthy persons: A double‐blind, placebo‐controlled, cross‐over study (1988) (13)
- Extracellular allosteric Na(+) binding to the Na(+),K(+)-ATPase in cardiac myocytes. (2013) (11)
- Myocardial cation transport. (1993) (11)
- Short chain fatty acids in inflammatory bowel disease. The effect of bacterial fermentation of blood. (1988) (11)
- Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion. (2016) (11)
- Decomposition of wheat bran and ispaghula husk in the stomach and the small intestine of healthy men. (1988) (11)
- Silencing overexpression of FXYD3 protein in breast cancer cells amplifies effects of doxorubicin and γ-radiation on Na+/K+-ATPase and cell survival (2016) (11)
- Membrane accessibility of glutathione. (2015) (10)
- Kinetic comparisons of heart and kidney Na+,K(+)-ATPases. (2012) (9)
- Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab. (2021) (9)
- Routine aspiration thrombectomy improves the diagnosis and management of embolic myocardial infarction (2016) (9)
- Thyroid status and Na(+)-K+ pump current, intracellular sodium, and action potential duration in rabbit heart. (1995) (9)
- Cyclosporine and FK506 differentially regulate the sarcolemmal Na(+)-K(+) pump. (2001) (9)
- Batimastat and Marimastat in Cancer (1999) (9)
- Procedural and in-patient outcomes in patients aged 80 years or older undergoing contemporary primary percutaneous coronary intervention. (2012) (9)
- P152 CLINICAL ACTIVITY OF AK002, AN ANTI-SIGLEC-8 ANTIBODY, IN MULTIPLE FORMS OF UNCONTROLLED CHRONIC URTICARIA (2019) (8)
- 929b Larazotide Acetate, a First In-Class, Novel Tight Junction Regulator, Meets Primary Endpoint and Significantly Reduces Signs and Symptoms of Celiac Disease in Patients on a Gluten-Free Diet: Results of a Multicenter, Randomized, Placebo Controlled Trial (2014) (8)
- Evidence for electrogenic Na+ pumping in human atrial myocardium. (1984) (7)
- "Don't flog the heart!" - development of specific drug therapies for heart failure. (2007) (7)
- Characterization of a sodium pump-induced hyperpolarization in isolated human atrium. (1986) (7)
- Thyroid status and regulation of intracellular sodium in rabbit heart. (1997) (7)
- A primary stenting strategy as an alternative to fibrinolytic therapy in acute myocardial infarction: An analysis of results in hospital and at 6 weeks and 6 months (1999) (7)
- Glutathionylation of erythrocyte Na–K pump in heart failure: a novel biomarker that reflects a key oxidative abnormality in the heart (2012) (6)
- Clinical intervention studies on magnesium in myocardial infarction. (1989) (6)
- Looking into anti-angiogenic gene therapies for disorders of the eye. (2001) (6)
- Trial of a trial by media (2001) (6)
- AK002, an Anti-Siglec-8 Antibody, Depletes Tissue Eosinophils and Improves Dysphagia Symptoms in Patients with Eosinophilic Esophagitis (2020) (6)
- Targeting Cardiac Myocyte Na+-K+ Pump Function With β3 Adrenergic Agonist in Rabbit Model of Severe Congestive Heart Failure (2020) (6)
- Chronic amiodarone-induced inhibition of the Na+-K+ pump in rabbit cardiac myocytes is thyroid-dependent: comparison with dronedarone. (2003) (6)
- Outcomes by day and night for patients bypassing the emergency department presenting with ST-segment elevation myocardial infarction identified with a pre-hospital electrocardiogram. (2015) (5)
- Left bundle branch block without concordant ST changes is rarely associated with acute coronary occlusion. (2013) (5)
- Phase 1b Study of AK002, an Anti-Siglec-8 Monoclonal Antibody, in Patients with Severe Allergic Conjunctivitis (KRONOS Study) (2020) (5)
- A randomized phase II study of BB-10010: a variant of human macrophage inflammatory protein-1alpha for patients receiving high-dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer. (1997) (5)
- A randomized double blind placebo controlled multicenter pilot study of the safety and feasibility of AdGVVEGF121.10 via an intramyocardial injection catheter in patients with advanced coronary artery disease (2003) (4)
- Justification for intravenous magnesium therapy in acute myocardial infarction. (1988) (4)
- Procedural and In-patient Outcomes in Patients Aged 80 Years or Older Undergoing Contemporary Primary Percutaneous Coronary Intervention (2012) (4)
- Thermodynamic energy stability and in vitro potassium exchange capacity of ZS-9, a novel selective cation trap for the treatment of hyperkalemia (2014) (4)
- Protein kinase Cepsilon contributes to regulation of the sarcolemmal Na(+)-K(+) pump. (2001) (4)
- Abstract 17142: Treatment With a Beta3 Adrenergic Receptor Agonist in Heart Failure Reverses an Oxidative Modification and Inhibition of the Na+-K+ Pump in Cardiac Myocytes and Improves Pulmonary Congestion (2013) (4)
- ACID BASE, ION DISORDERS, LITHISASIS (2014) (3)
- FO012NORMALIZATION OF SERUM BICARBONATE WITH SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) IN THE PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED HARMONIZE STUDY (2015) (3)
- [Colloids versus crystalloids in the treatment of hypovolemic or septic shock]. (1989) (3)
- Angiotensin regulates the selectivity of the Na 1K 1 pump for intracellular Na 1 (1999) (3)
- Clinical Activity of AK002, an Anti-Siglec-8 Monoclonal Antibody, in Treatment-Refractory Chronic Urticaria (2020) (3)
- Mechanisms of Na+-K+ pump regulation in cardiac myocytes during hyposmolar swelling. (1999) (3)
- 5-(N,N-dimethyl)amiloride-sensitive Na-Li exchange in isolated specimens of human atrium. (1988) (3)
- Justification for magnesium therapy in acute ischaemic heart disease. Clinical and experimental studies. (1993) (3)
- D451 CLINICAL ACTIVITY OF AK002, AN ANTI-SIGLEC-8 ANTIBODY, IN SEVERE ALLERGIC CONJUNCTIVITIS AND COMORBID ATOPIC DISEASES (2019) (3)
- Oxidative regulation of the Na+ -K+ pump in cardiac physiology and pathology: clarifying the published evidence. (2013) (2)
- ZS-9 MAINTAINS NORMOKALEMIA IN HYPERKALEMIC PATIENTS DESPITE CONTINUING RAAS INHIBITORS: A SUBGROUP ANALYSIS FROM A PHASE 3 MULTICENTER, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL (2015) (2)
- Fr198 GASTRODUODENAL EOSINOPHILIA IS UNDER-APPRECIATED IN EOSINOPHILIC ESOPHAGITIS (EOE) PATIENTS WITH FUNCTIONAL BOWEL SYMPTOMS: A REAL LIFE EXPERIENCE (2021) (2)
- [PP.35.03]: SODIUM ZIRCONIUM CYCLOSILICATE FOR TREATMENT OF HYPERKALAEMIA ANALYSIS OF PATIENTS ON RENIN-ANGIOTENSIN-ALDOSTERONE INHIBITORS (RAASI) FROM THE PHASE 3 HARMONIZE STUDY (2015) (2)
- ZS-9, A NOVEL SELECTIVE CATION TRAP, LEADS TO A RAPID AND PREDICTABLE RATE OF DECLINE IN SERUM POTASSIUM IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERKALEMIA (2014) (2)
- TREATMENT OF HYPERKALEMIA WITH ZS-9, A SELECTIVE NONABSORBED CATION EXCHANGE RESIN, DOES NOT LEAD TO HYPOMAGNESEMIA: RESULTS FROM TWO MULTICENTER, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED PHASE 3 TRIALS (2015) (2)
- Abstract 13555: Acute Efficacy of Sodium Zirconium Cyclosilicate (ZS-9) in Patients on Mineralocorticoid-Receptor Antagonists: Analysis From Two Phase 3 Studies (2015) (2)
- Voltage‐Dependent Inhibition of the Na+‐K+ Pump by Intracellular Potassium in Rabbit Venticular Myocytes (1997) (2)
- Effect of ZS-9, a novel selective cation trap, on urinary potassium and sodium excretion when used for the treatment of hyperkalemia in patients with chronic kidney disease (2014) (2)
- ACUTE-PHASE EFFICACY OF ZS-9 IN PATIENTS WITH BASELINE SERUM POTASSIUM LEVELS ABOVE 5.5 MEQ/L: ANALYSIS FROM A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL (2015) (2)
- On the effect of unstirred layers on K+-activated electrogenic Na+ pumping in cardiac Purkinje strands. (1986) (2)
- 932 HISTOLOGIC AND SYMPTOMATIC IMPROVEMENT ACROSS MULTIPLE FORMS OF EOSINOPHILIC GASTROINTESTINAL DISEASES IN ENIGMA, A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ANTOLIMAB (AK002) (2020) (2)
- Abstract 16278: {beta}3 Adrenergic Stimulation Protects Against eNOS Uncoupling, Oxidative Na+-K+ Pump Inhibition and Vascular Dysfunction in Type 2 Diabetes (2012) (2)
- Sodium zirconium cyclosilicate (ZS-9) treatment in patients with serum potassium >6.5 mEq/L (2015) (2)
- Batimastat and Marimastat in Cancer: Summary of Early Clinical Data (1998) (2)
- S-glutathionylation of the Na +-K + pump: a novel redox mechanism in preeclampsia. (2020) (1)
- RAPID ONSET OF POTASSIUM:LOWERING WITH SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) ACROSS PATIENTS STRATIFIED BY RACE, AGE, AND COMORBIDITIES IN THE RANDOMIZED, DOUBLE:BLIND, PLACEBO:CONTROLLED PHASE 3 HARMONIZE STUDY (2016) (1)
- Fr178 ACTIVATED MAST CELLS AND EOSINOPHILS ARE ASSOCIATED WITH INCREASED INFLAMMATORY MEDIATORS IN MUCOSAL BIOPSIES FROM PATIENTS WITH CHRONIC GASTROINTESTINAL SYMPTOMS (2021) (1)
- 1246 Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis Endure a Lengthy Path to Diagnosis and Experience Persistent Symptoms After Diagnosis (2019) (1)
- ZS-9 once-daily maintained serum K+ in hyperkalemic subjects on RAAS therapy: subgroup analysis from a phase 3, multicenter, randomized, double-blind, placebo-controlled trial (2014) (1)
- FP007EFFICIENCY OF SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) INCREASES WITH SEVERITY OF HYPERKALAEMIA: SUBGROUP ANALYSIS OF PATIENTS STRATIFIED BY BASELINE POTASSIUM IN THE PHASE 3 HARMONIZE STUDY (2015) (1)
- Electrophysiological Effects of Intravenous UK-68, 798, a New Class III Antiarrhythmic Agent (1991) (1)
- FP010MAINTENANCE OF NORMAL SERUM POTASSIUM WITH SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) IN SUBGROUP OF PATIENTS WITH HISTORY OF CHRONIC KIDNEY DISEASE AND ON RAAS INHIBITORS FROM THE PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED HARMONIZE STUDY (2015) (1)
- [Short chain fatty acids in the human large intestine. The significance for gastrointestinal health and disease]. (1988) (1)
- EFFECT OF SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) ON URINARY POTASSIUM AND SODIUM: AN ANALYSIS OF THE PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED HARMONIZE STUDY (2015) (1)
- 539 LONG-TERM TREATMENT OF PATIENTS WITH EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC DUODENITIS WITH LIRENTELIMAB, A MONOCLONAL ANTIBODY AGAINST SIGLEC-8 (2021) (1)
- ACHIEVEMENT AND MAINTENANCE OF NORMOKALAEMIA IN PATIENTS WITH NON-DIALYSIS STAGE 5 CHRONIC KIDNEY DISEASE (2015) (1)
- FP008ACHIEVEMENT OF NORMAL SERUM POTASSIUM WITH SODIUM ZIRCONIUM CYCLOSILICATE (ZS-9) IN A SUBGROUP OF PATIENTS WITH STAGE 4/5 CHRONIC KIDNEY DISEASE AND BASELINE POTASSIUM ≥5.5 MMOL/L FROM THE PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED HARMONIZE STUDY (2015) (1)
- Tu1251 MAST CELLS ARE SIGNIFICANTLY ACTIVATED IN PATIENTS WITH ULCERATIVE COLITIS AND ARE INHIBITED BY AN ANTI-SIGLEC-8 ANTIBODY, ANTOLIMAB (AK002) (2020) (1)
- EoE Biopsies have Elevated and Activated Mast Cells that Produce Cytokines and Chemokines that Drive Disease Pathogenesis (2020) (1)
- Change from baseline in serum K+ with ZS-9 in patients with chronic kidney disease treated for hyperkalemia (2014) (1)
- 1247 Development of a Patient Reported Outcome (PRO) Questionnaire to Assess the Symptoms of Eosinophilic Gastritis and Gastroenteritis (EG/EGE-SQ©) (2019) (1)
- 257 Sodium Zirconium Cyclosilicate for Patients With Severe Hyperkalemia: Subgroup Analysis of the Phase 3, International, Multicenter, Randomized, Double-Blind, Placebo-Controlled HARMONIZE Trial (2015) (1)
- ZS-9 for treatment of hyperkalemia in black patients: subgroup analysis from the phase 3 HARMONIZE study (2015) (1)
- The effectiveness of ZS-9 in achieving normokalemia during the open-label phase of the HARMONIZE trial (2015) (1)
- Long-term safety and efficacy of intramuscular administration of Cl-1023 (AdGVVEGF121.10) in patients with intermittent claudication (2002) (1)
- Treatment with a beta3 Adrenergic Receptor Agonist in Heart Failure Reverses Inhibition of the Na+–K+ Pump in Cardiac Myocytes and Improves Pulmonary Congestion (2013) (1)
- Glutathionylation of the β1 Subunit Prevents the E1Na3 to E2P Forward Reaction in the Na+, K+ ATPase (2014) (1)
- The “Obesity Paradox” in a Contemporary ST Elevation Myocardial Infarction (STEMI) Cohort (2016) (1)
- Abstract 1379: Angiotensin II Inhibits the Na+-K+ pump via PKC-dependent Activation of NAD(P)H Oxidase (2008) (1)
- Activation of sodium-hydrogen exchange in heart cells by hyperosmolar solutions (1990) (1)
- Redox Regulation of Na+–K+ Pump in Vascular Smooth Muscle Cells: Implications for Vascular Tone in Heath and Disease (2012) (1)
- Does emergency triage of acute myocardial infarction (ETAMI) increase unnecessary coronary angiography? A 5-year comparison of Field Triage versus Emergency Department Triage (2009) (1)
- The Impact of Aspiration Thrombectomy on the Diagnosis and Outcomes of Coronary Embolism (2011) (1)
- Emergency surgery for AMI patients with fibrinolysis failure or contraindication not suitable for percutaneous intervention (2000) (0)
- 1009-47 Effect of Insulin on Electrogenic Na+-K+ Pump Current in Isolated Rabbit Ventricular Myocytes (1995) (0)
- Consideration of natriuretic peptide receptor C. (2011) (0)
- Spontaneous Coronary Artery Dissection: A Single Centre Case Series (2012) (0)
- Angiotensin regulates the selectivity of the Na+-K+ pump for intracellular Na+. (1999) (0)
- The Changing Face of STEMI Patients – Then and Now (2016) (0)
- From Bench-Based PhD Project to First-in-Man Use of β3 Adrenergic Agonist in Patients with Treatment-Resistant Decompensated Congestive Heart Failure (2017) (0)
- Beta3 adrenergic stimulation confers trophoblast protection against oxidative damages from hypoxia-reoxygenation injury through the endothelial nitric oxide synthase-mediated NADPH oxidase signaling pathway (2021) (0)
- Not all cardiac glycosides are equal: Could ouabain prove to be better than digoxin for heart failure? (2015) (0)
- Na+/K+-ATPase-associated FXYD3 Protein As An Intracellular Therapeutic Target in Cancer (2020) (0)
- Antioxidant Effect of Beta-1 Adrenergic Receptor Blockade Through Macromolecular Remodelling of An Oxidative Pathway: New Tricks of An Old Dog (2012) (0)
- Selective Activation of β3 Adrenoceptors Protects Against Type 2 Diabetes-induced eNOS Uncoupling, Oxidative Na+–K+ Pump Inhibition and Vascular Dysfunction (2013) (0)
- Extracellular Allosteric Na D Binding to the Na D ,K D -ATPase in Cardiac Myocytes (2013) (0)
- Raised Neutrophil-Lymphocyte Ratio following acute STEMI is associated with increased rates of Re-infarction and Mortality at 1 year (2015) (0)
- A cautionary tale for multivessel stenting during acute myocardial infarction: Significant vasoconstriction of non-culprit lesions (2003) (0)
- Can acute myocardial infarction be predicted on presentation in patients with persistent chest pain without significant ST segment elevation (2003) (0)
- The N-3 polyunsaturated fatty acid eicosapentanoic acid (EPA) stimulates the NaK pump in rabbit cardiac myocytes (2000) (0)
- Co-location of a private cardiac catheter laboratory within a university teaching hospital: An initial six month experience (2000) (0)
- Nitric Oxide-Activated Guanylyl Cyclase Modulates NAD(P)H Oxidase and Oxidative Inhibition of the Na+–K+ Pump in Ventricular Myocytes in a Phosphatase Dependent Manner (2009) (0)
- Primary Percutaneous Coronary Intervention is associated with less myocardial injury in an older population (2009) (0)
- A dose-ranging study ofUK-68,798, anovel class III anti-arrhythmic agent, innormal volunteers (1991) (0)
- Metoprolol Stimulates the Cardiac Na+–K+ Pump by Reducing the Baseline Glutathiolynation of its beta1 Subunit (2010) (0)
- Glutathionylation Mediates Angiotensin II-induced Uncoupling of Endothelial Nitric Oxide Synthase and Endothelial Dysfunction (2012) (0)
- 847 Lactate to Albumin Ratio (LAR) Predicts In-Hospital Mortality in Patients Presenting With ST Elevation Myocardial Infarction (STEMI) (2020) (0)
- Silencing FXYD3 protein enhances cytotoxicity effect of doxorubicin and gamma irradiation in human breast cancer cells (2014) (0)
- Inhibition of Na+-K+ pumping in human tissue by cardiac steroids (1994) (0)
- Field Triage Reduces the Incidence and Mortality of Ischaemic Cardiogenic Shock in Patients with Acute Myocardial Infarction (2010) (0)
- Myocardial injury following Primary Percutaneous Coronary Intervention (PCI) is comparable in patients with multi-vessel disease compared to single vessel disease (2009) (0)
- (cid:1) 3 Adrenergic Stimulation of the Cardiac Na (cid:2) -K (cid:2) Pump by Reversal of an Inhibitory Oxidative Modification (2010) (0)
- In vivo Function and Oxidative Modification of the Na+–K+ Pump in an Infarct Model of Heart Failure (2012) (0)
- Incidence, Risk Factors, and In-Hospital Mortality of Contrast-Induced Nephropathy in Field Triaged Patients with Acute Myocardial Infarction (2010) (0)
- Ventricular Myocardial Cells (2005) (0)
- Field Triage for ST Elevation Myocardial Infarction Reduces the Incidence of Cardiogenic Shock and Subsequent In-patient Mortality (2012) (0)
- Urgent transfer of rural and district hospital AMI patients with fibrinolysis failure or contraindication for immediate coronary angiography ± intervention is feasible and safe (2000) (0)
- Abstract 177: Promotion Of Nitroso-redox Balance By Beta 3 Adrenoceptor Agonism: Therapeutic Implications For Cardiovascular Complications Of Diabetes (2014) (0)
- Treatment with β3 adrenergic agonists reverses impaired cardiac myocyte Na+ export and improves severely decompensated heart failure; a clinical application of an experimental finding (2019) (0)
- β3 Adrenergic Receptor Stimulates the Cardiac Na/K Pump via an NO-dependent Pathway and Reduces Oxidative Modification of the β1 Pump Subunit (2009) (0)
- In vivo effect of aldosterone on the cardiac Na+-K+ pump (1998) (0)
- Electrocardiographic features of left circumflex coronary artery occlusion in patients presenting with acute myocardial infarction (2000) (0)
- A novel kinetic model based on the Albers-Post scheme that mimics the behaviour of the Na+, K+-ATPase in situ (2015) (0)
- Mo1236 MAST CELL LEVEL AND CLINICAL CORRELATES IN PATIENS WITH EOSINOPHILIC GASTRITIS AND GASTROENTERITIS (2020) (0)
- Abstract 503: Maintenance of Normokalemia with ZS-9 Once Daily in CHF Patients on RAAS Inhibitors: Subgroup Analysis of a Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Hyperkalemia (2014) (0)
- Acute Coronary Collaterals Reduce Mortality and Improve Left Ventricular Function in Patients Presenting with ST Elevation Myocardial Infarction (STEMI) (2019) (0)
- 867 EGID BIOPSIES HAVE FUNCTIONALLY DISTINCT AND ACTIVATED MAST CELLS THAT CONTRIBUTE TO DISEASE PATHOGENESIS AND ARE INHIBITED BY AN ANTI-SIGLEC-8 ANTIBODY, ANTOLIMAB (AK002) (2020) (0)
- Miscellaneous Acute Renal Failure: Multivariate Analysis of Causes and Risk Factors (1983) (0)
- Fr173 OPTIMIZATION OF EOSINOPHILIC GASTRITIS/DUODENITIS DETECTION REQUIRES EVALUATION OF MULTIPLE HIGH-POWERED FIELDS IN EACH OF 8 GASTRIC AND 4 DUODENAL BIOPSIES: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
- P0620OXIDANT-INDUCED RENAL PRECONDITIONING BIOMARKERS FOR AKI PREVENTION WITH RBT-1 (2020) (0)
- Abstract 509: Thermodynamic Energy Stability and In Vitro Potassium Exchange by ZS-9, a Novel Selective Cation Trap for Treatment of Hyperkalemia (2014) (0)
- CKD PATHOPHYSIOLOGY AND CLINICAL STUDIES (2014) (0)
- Mo1237 ESTABLISHMENT OF NORMAL TISSUE MAST CELL LEVELS IN GASTRIC AND DUODENAL BIOPSIES OF PATIENTS WTHOUT GASTROINTESTINAL DISEASE (2020) (0)
- cGMP Compartmentalization Accounts for the Bi-phasic Effect of ANP on Na+–K+ Pump in Cardiac Myocytes (2009) (0)
- [Magnesium and cardiovascular disease. I. Do patients with ischemic heart disease suffer from magnesium deficiency?]. (1988) (0)
- Ouabain-Induced Stimulation of Sodium Potassium Pump Activity is Transient in Cardiac Myocytes (2018) (0)
- Structure of ZS-9. (2014) (0)
- 1244 Symptomatic Patients Suspected of Eosinophilic Gastritis and/or Enteritis Have Elevated Mucosal Mast Cell Counts Without Eosinophilia: A New Diagnostic Entity? (2019) (0)
- Fr191 EOSINOPHILIC GASTRITIS AND EOSINOPHILIC DUODENITIS EXHIBIT A SIMILAR CLINICAL PRESENTATION, UNDERSCORING THE NEED FOR COLLECTION OF MULTIPLE BIOPSIES FROM BOTH THE STOMACH AND DUODENUM TO EVALUATE FOR TISSUE EOSINOPHILIA: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
- Mo1163 – Eg and Eoe Patient Biopsies Have High Numbers of Activated Eosinophils and Mast Cells that are Inhibited by Ak002 (2019) (0)
- Abstract 16681: Effect of ZS-9 Treatment for Hyperkalemia in Patients With Heart Failure Receiving Maximal, Submaximal or no Renin-angiotensin-aldosterone-system Inhibitors: Pooled Analysis From Two Phase III Trials (2016) (0)
- P159 PHENOTYPIC CHARACTERIZATION OF INFLAMMATORY BOWEL DISEASE BIOPSIES REVEAL THAT MAST CELLS ARE SIGNIFICANTLY ELEVATED AND ACTIVATED IN PATIENTS WITH ULCERATIVE COLITIS (2020) (0)
- Methods and compositions for treating myocardial affections (2005) (0)
- Mo1127 – Mast Cells in Addition to Eosinophils are Markedly Elevated At Baseline in Patients with Eosinophilic Gastritis And/Or Gastroenteritis (2019) (0)
- Models of colonic short chain fatty acid transport (1988) (0)
- Fr176 ENDOSCOPIC APPEARANCE DOES NOT PREDICT THE PRESENCE OF HISTOLOGIC EOSINOPHILIC GASTRITIS AMONG SYMPTOMATIC ADULTS, INDICATING THAT COLLECTION AND EVALUATION OF BIOPSIES SHOULD OCCUR REGARDLESS OF ENDOSCOPIC APPEARANCE: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
- S1330 High Discovery Rate of Previously Undiagnosed Patients With Eosinophilic Gastritis and Duodenitis Using a Systematic Endoscopic Biopsy Protocol: Screening Data Analysis From ENIGMA, a Randomized Controlled Trial (2020) (0)
- Cyclosporine and FK 506 Differentially Regulate the Sarcolemmal Na 1K 1 Pump (2001) (0)
- Abstract 14686: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Once-Daily ZS-9 for Treatment of Hyperkalemia: Achievement and Maintenance of K+ in Subgroup Analysis of Patients with Significant Renal Impairment and Heart Failure (2014) (0)
- The Role of Metalloprotease Inhibitors in Cancer and Chronic Inflammatory Diseases (2000) (0)
- Abstract 635: Achievement of Normokalemia with ZS-9 Across Subgroups in a Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Patients with Hyperkalemia (2014) (0)
- New Agents for Hyperkalemia REPLY (2015) (0)
- 278 PRIMARY RESULTS OF A PHASE 1 MULTICENTER OPEN-LABEL STUDY OF ANTOLIMAB, AN ANTI-SIGLEC-8 ANTIBODY, FOR THE TREATMENT OF PATIENTS WITH CHRONIC GASTROINTESTINAL SYMPTOMS AND ELEVATED GASTRIC AND/OR DUODENAL MAST CELLS (2020) (0)
- Abstract 17489: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Once-Daily ZS-9 for Treatment of Hyperkalemia: Achievement and Maintenance of K+ in Subgroup Analysis of Patients with Heart Failure not on RAAS Inhibitors (2014) (0)
- Trends in Opioid Analgesic Abuse and Mortality in the United States (2015) (0)
- Electrophysiologic Profile and Efficacy of Intravenous Do#efWe/e UK-68,798), a New Class III Antiarrh I 63 mic Patients with Sustaine Drug, in Monomorphic Ventricular Tachycardia (1995) (0)
- P-004. A novel use of β3 adrenergic receptor agonist in treating preeclampsia (2021) (0)
- Heart Failure and CardiomyopathiesACHIEVEMENT OF NORMOKALEMIA IN HEART FAILURE PATIENTS NOT ON RENIN:ANGIOTENSIN:ALDOSTERONE SYSTEM INHIBITORS: POOLED ANALYSIS FROM TWO PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE:BLIND, PLACEBO:CONTROLLED TRIALS OF SODIUM ZIRCONIUM CYCLOSILICATE FOR TREATMENT OF HYPERK (2016) (0)
- Maintenance of normokalemia with sodium zirconium cyclosilicate (ZS-9) in patients with heart failure on RAAS inhibitors: Subgroup analysis of a phase 3, randomized, placebo-controlled trial (2015) (0)
- 851 Long Term Angiographic Follow-Up of Saphenous Vein Graft Interventions Using Distal Embolisation Protection Devices (2020) (0)
- ACELL September 46/3 (1999) (0)
- Normalization of Serum Potassium With Sodium Zirconium Cyclosilicate (ZS-9) in Patients With Heart Failure (2015) (0)
- Predictors of Radiation Exposure During ST Elevation Myocardial Infarction (STEMI) (2019) (0)
- [Magnesium and cardiovascular disease. II. The significance of magnesium deficiency for cardiovascular disease]. (1988) (0)
- Angiographic Predictors of Coronary Haemodynamics: The FFR Is Not Affected by Lesion Length or Location (2018) (0)
- RARE SALAMI trial revisited (2002) (0)
- 228 INTERIM RESULTS OF AN OPEN-LABEL EXTENSION STUDY OF ANTOLIMAB, AN ANTI-SIGLEC-8 ANTIBODY, FOR THE TREATMENT OF PATIENTS WITH EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC ENTERITIS (2020) (0)
- Stimulation of β3 Adrenergic Signalling Reverses Diabetes-Induced Oxidative Inhibition of Sarcolemmal Na+–K+ pump (2013) (0)
- PKA inhibits the Na+–K+pump in cadiac myocytes via superoxide (2006) (0)
- S3146 Patients With Eosinophilic Esophagitis (EoE) and Persistent Extra-Esophageal GI Symptoms Should Be Evaluated for Eosinophilic Gastritis (EG) and Eosinophilic Duodenitis (EoD) (2020) (0)
- 621 PL02.05 LONG-TERM TREATMENT OF PATIENTS WITH EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC DUODENITIS WITH LIRENTELIMAB, A MONOCLONAL ANTIBODY AGAINST SIGLEC-8 (2021) (0)
- Prediction of Outcome in Acute Renal Failure bv Discriminant Analysis of Clinical Variables (1986) (0)
- Targeting cardiac myocyte Na+-K+ pump function with β3 adrenergic agonist in rabbits and patients with severe congestive heart failure (2019) (0)
- High pressure treatment of foods (1998) (0)
- Abstract 508: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Once-Daily ZS-9 for Treatment of Hyperkalemia: Maintenance of Serum K + in Subgroup Analysis of Patients on RAAS Therapy (2014) (0)
- Siglec—8, a Novel Selective Target for Eosinophilic Gastrointestinal Diseases (EGIDs) Found on Eosinophils and Mast Cells in Human Tissue (2018) (0)
- PKA/PKC cross-talk mediates NADPH oxidase-induced Na+–K+ pump inhibition in cardiac myocytes (2007) (0)
- Left Bundle Branch Block without superadded ST elevation is rarely associated with significant myocardial injury in the setting of field triage to primary angioplasty (2009) (0)
- Oxidative inhibition of erythrocyte Na+-K+ pump in diabetes: A functionally relevant circulating marker of oxidative stress (2012) (0)
- 832 Graft Versus Native Vessel Intervention for Patients With Previous Bypass Surgery Undergoing Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction (2020) (0)
- Dependence of Na (cid:1) -K (cid:1) pump current-voltage relationship on intracellular Na (cid:1) , K (cid:1) , and Cs (cid:1) in rabbit cardiac myocytes (2002) (0)
- VENTRICULAR PREMATURE BEATS INDUCED BY CONTRAST ECHOCARDIOGRAPHY IN AN ANIMAL MODEL (2003) (0)
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