Howard Lipshitz
#168,546
Most Influential Person Now
American and Canadian biologist
Howard Lipshitz's AcademicInfluence.com Rankings
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Biology
Howard Lipshitz's Degrees
- PhD Biology University of British Columbia
Why Is Howard Lipshitz Influential?
(Suggest an Edit or Addition)According to Wikipedia, Howard David Lipshitz is an American and Canadian biologist who does genetic research on the fruit fly, Drosophila. Early life and education Lipshitz was born and raised in Durban, South Africa, where he attended the University of Natal , obtaining a B.Sc. in Biological Sciences and Mathematical Statistics and a B.Sc. cum laude in Biological Sciences . He completed his M. Phil. and Ph.D. degrees in Biology at Yale University with Douglas R. Kankel, working on Drosophila developmental neurogenetics. He then carried out postdoctoral research in the Biochemistry Department at Stanford University with David Hogness, where he defined the first long non-coding RNA, from the Bithorax complex of Drosophila.
Howard Lipshitz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A compendium of RNA-binding motifs for decoding gene regulation (2013) (1214)
- The maternal-to-zygotic transition: a play in two acts (2009) (994)
- Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. (1988) (552)
- RNA localization in development. (1998) (354)
- SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. (2007) (299)
- A Vertebrate Polycomb Response Element Governs Segmentation of the Posterior Hindbrain (2009) (259)
- Smaug Recruits the CCR4/POP2/NOT Deadenylase Complex to Trigger Maternal Transcript Localization in the Early Drosophila Embryo (2005) (258)
- Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster (1999) (236)
- Spatial and temporal control of RNA stability (2001) (200)
- Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage. (1999) (188)
- The maternal-to-zygotic transition revisited (2019) (181)
- Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure. (2010) (181)
- Mechanisms of RNA localization and translational regulation. (2000) (175)
- Novel transcripts from the Ultrabithorax domain of the bithorax complex. (1987) (172)
- Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate (1996) (166)
- Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code (2000) (165)
- Dynamic Hsp83 RNA localization during Drosophila oogenesis and embryogenesis (1993) (159)
- Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila (1997) (155)
- Specification and development of the pars intercerebralis and pars lateralis, neuroendocrine command centers in the Drosophila brain. (2007) (149)
- Transcript clearance during the maternal-to-zygotic transition. (2011) (143)
- An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition (2009) (137)
- Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila (2005) (126)
- Integrin-Dependent Apposition of Drosophila Extraembryonic Membranes Promotes Morphogenesis and Prevents Anoikis (2004) (116)
- Localized RNAs and their functions (1993) (110)
- Control of germ-band retraction in Drosophila by the zinc-finger protein HINDSIGHT. (1997) (106)
- Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning. (1990) (105)
- Downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo (2001) (102)
- Differential distributions of two adducin-like protein isoforms in the Drosophila ovary and early embryo (1996) (100)
- Finding the target sites of RNA-binding proteins (2013) (98)
- Regulation and products of the Ubx domain of the bithorax complex. (1985) (95)
- Regulation of maternal transcript destabilization during egg activation in Drosophila. (2003) (93)
- Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors. (2016) (87)
- Reciprocal effects of hyper- and hypoactivity mutations in the Drosophila pattern gene torso. (1989) (86)
- Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein (2014) (85)
- HuR Is Required for IL-17–Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization (2013) (84)
- Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition (2015) (79)
- Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity (2013) (78)
- Different genetic requirements for anterior RNA localization revealed by the distribution of Adducin-like transcripts during Drosophila oogenesis. (1993) (77)
- Staufen2 regulates neuronal target RNAs. (2013) (74)
- Drosophila Maternal Hsp83 mRNA Destabilization Is Directed by Multiple SMAUG Recognition Elements in the Open Reading Frame (2008) (69)
- Role of the amnioserosa in germ band retraction of the Drosophila melanogaster embryo. (1999) (68)
- Regulation and Function of Maternal Gene Products During the Maternal-to-Zygotic Transition in Drosophila. (2015) (65)
- Eye evolution at high resolution: the neuron as a unit of homology. (2009) (64)
- Specificity of gene action during central nervous system development in Drosophila melanogaster: analysis of the lethal (1) optic ganglion reduced locus. (1985) (60)
- Spatially regulated expression of retrovirus-like transposons during Drosophila melanogaster embryogenesis. (1994) (56)
- Role of Adducin-like (hu-li tai shao) mRNA and protein localization in regulating cytoskeletal structure and function during Drosophila Oogenesis and early embryogenesis. (1996) (56)
- Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells (2012) (50)
- Conserved Role of the Vsx Genes Supports a Monophyletic Origin for Bilaterian Visual Systems (2008) (48)
- The hindsight gene is required for epithelial maintenance and differentiation of the tracheal system in Drosophila. (2000) (46)
- The mother-to-child transition. (2007) (44)
- achaete-scute feminizing activities and Drosophila sex determination. (1993) (42)
- ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition (2017) (40)
- Different 3' untranslated regions target alternatively processed hu-li tai shao (hts) transcripts to distinct cytoplasmic locations during Drosophila oogenesis. (1999) (40)
- The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes (2017) (38)
- Mitochondrially encoded 16S large ribosomal RNA is concentrated in the posterior polar plasm of early Drosophila embryos but is not required for pole cell formation. (1994) (38)
- Control of photoreceptor cell morphology, planar polarity and epithelial integrity during Drosophila eye development. (2002) (38)
- A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis (2015) (36)
- Follow the mRNA: a new model for Bicoid gradient formation (2009) (32)
- A Multiprotein Complex That Mediates Translational Enhancement in Drosophila* (2007) (32)
- Regulation and function of maternal mRNA destabilization during early Drosophila development. (2007) (31)
- RNA localization and translational regulation during axis specification in the Drosophila oocyte. (2001) (28)
- The maternal-to-zygotic transition (2015) (27)
- A molecular screen for polar-localised maternal RNAs in the early embryo of Drosophila (1993) (26)
- The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms. (2020) (25)
- Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition (2019) (23)
- A high-throughput pipeline for the production of synthetic antibodies for analysis of ribonucleoprotein complexes (2016) (21)
- The RNA-Binding Protein Rasputin/G3BP Enhances the Stability and Translation of Its Target mRNAs. (2020) (21)
- Hindsight modulates Delta expression during Drosophila cone cell induction (2009) (21)
- Axis specification in the Drosophila embryo. (1991) (19)
- Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo. (1991) (18)
- The Smaug RNA-Binding Protein Is Essential for microRNA Synthesis During the Drosophila Maternal-to-Zygotic Transition (2016) (18)
- Dose-Sensitive Autosomal Modifiers Identify Candidate Genes for Tissue Autonomous and Tissue Nonautonomous Regulation by the Drosophila Nuclear Zinc-Finger Protein, Hindsight (2004) (18)
- Synthetic antibodies as tools to probe RNA-binding protein function. (2012) (17)
- Drosophila Hindsight and mammalian RREB-1 are evolutionarily conserved DNA-binding transcriptional attenuators. (2013) (17)
- Post-transcriptional regulation of gene expression. (2017) (16)
- From fruit flies to fallout: Ed Lewis and his science (2004) (8)
- Genes, development, and cancer : the life and work of Edward B. Lewis (2004) (8)
- Measuring mRNA stability during early Drosophila embryogenesis. (2008) (8)
- Genetic control of cell fate in the termini of the Drosophila embryo. (1992) (6)
- From fruit flies to fallout: Ed Lewis and his science (2005) (6)
- Regulation of the RNA‐binding protein Smaug by the GPCR Smoothened via the kinase Fused (2020) (6)
- Opposing roles for Egalitarian and Staufen in transport, anchoring and localization of oskar mRNA in the Drosophila oocyte (2021) (6)
- Genes, Development, and Cancer (2004) (6)
- Supplemental Data Smaug Recruits the CCR 4 / POP 2 / NOT Deadenylase Complex to Trigger Maternal Transcript Localization in the Early Drosophila Embryo (2005) (4)
- Lewis, Edward B. (2013) (3)
- RNA localization (1999) (3)
- Lewis and the Somatic Effects of Ionizing Radiation (2004) (2)
- The Descent of Databases. (2021) (2)
- The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition. (2021) (2)
- The 2003 Thomas Hunt Morgan Medal; David S. Hogness. (2003) (2)
- Axis specification in the Drosophila embryo (1992) (2)
- Transcription Gets to the Checkpoint (2015) (2)
- Resynthesis or revisionism? (1996) (2)
- Drosophila Maternal Hsp83 mRNA Destabilization Is Directed by Multiple SMAUG Recognition Elements in the Open Reading Frame (2008) (2)
- Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition (2015) (1)
- The Maternal-to-Zygotic Transition. Preface. (2015) (1)
- Developmental interactions between the peripheral and central nervous system in Drosophila melanogaster: analysis of the mutant, two-faced. (1985) (1)
- Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells (2012) (1)
- The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes (2017) (1)
- The Origin of GENETICS. (2021) (1)
- The Terminal Gene Hierarchy of Drosophila and the Genetic Control of Tissue Specification and Morphogenesis (1996) (1)
- Author response: ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition (2017) (1)
- Role of Nanos and ‘S bodies’ in distinguishing somatic from germ cell fate in Drosophila (2009) (0)
- The translational repressor Smaug2 regulates maintenance of mammalian neural stem cells (2015) (0)
- Analysis of Lung Tumor Mortality in the Battelle Beagle Lifespan Experiment (2007) (0)
- Making biological knowledge useful for humans and machines. (2022) (0)
- The Expression of the Emotions in Man and Fruit Flies (2021) (0)
- Lewis and the Molecular Control of Development (2004) (0)
- Flying into the post-genome era. (2000) (0)
- Edward B. Lewis (2006) (0)
- E. B. Lewis and His Science (2004) (0)
- Question & Answer Q & A : Epistasis (2009) (0)
- Making biological knowledge useful for humans and machines. (2022) (0)
- Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the oskar and bruno 1 mRNAs (2023) (0)
- Lewis and the Nature of the Gene (2004) (0)
- complex.transcripts from the Ultrabithorax domain of the bithorax (2012) (0)
- The RNA-binding protein, Rasputin/G3BP, enhances the stability and translation of its target mRNAs (2020) (0)
- DynamicHsp83RNA Localization during Drosophila Oogenesis andEmbryogenesis (1993) (0)
- Global regulation of mRNA translation and stability in the early Drosophilaembryo by the Smaug RNA-binding protein (2014) (0)
- Lewis and the Genetic Control of Development (2004) (0)
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