Hugues de Thé
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French biologist
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Why Is Hugues de Thé Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hugues de Thé , is a French doctor and researcher. He is currently a hospital doctor and professor at the Collège de France, holder of the chair of cellular and molecular oncology , member of the French Academy of sciences since 2011. His work, at the interface between biology and medicine, has radically transformed the management of a rare form of leukaemia, which has become the paradigm for targeted cancer treatments.
Hugues de Thé's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. (1997) (772)
- Acute promyelocytic leukemia. (1993) (712)
- Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML (2010) (646)
- All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. (2004) (542)
- PML nuclear bodies. (2010) (525)
- Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as2O3-Induced Pml or Pml/Retinoic Acid Receptor α Degradation (2001) (509)
- Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia. (1997) (423)
- Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer (2012) (320)
- SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation. (1999) (315)
- Retinoic Acid and Arsenic Synergize to Eradicate Leukemic Cells in a Mouse Model of Acute Promyelocytic Leukemia (1999) (299)
- PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3. (2010) (286)
- PML protein expression in hematopoietic and acute promyelocytic leukemia cells. (1993) (258)
- A refined molecular taxonomy of breast cancer (2011) (257)
- Resistance to Virus Infection Conferred by the Interferon-Induced Promyelocytic Leukemia Protein (1998) (257)
- The PML growth-suppressor has an altered expression in human oncogenesis. (1995) (254)
- Induction of the PML protein by interferons in normal and APL cells. (1995) (241)
- Arsenic trioxide and interferon-alpha synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells. (1999) (192)
- Acute promyelocytic leukemia, arsenic, and PML bodies (2012) (188)
- PML mediates the interferon‐induced antiviral state against a complex retrovirus via its association with the viral transactivator (2001) (186)
- Acute Promyelocytic Leukemia: A Paradigm for Oncoprotein-Targeted Cure. (2017) (181)
- Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL). (2009) (179)
- p53 in breast cancer subtypes and new insights into response to chemotherapy. (2013) (174)
- Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins (2014) (171)
- Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin−Cyclophosphamide Regimen (2007) (170)
- Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells. (1998) (169)
- From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia. (2011) (168)
- PML–RARA-RXR Oligomers Mediate Retinoid and Rexinoid/cAMP Cross-Talk in Acute Promyelocytic Leukemia Cell Differentiation (2004) (163)
- High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors. (2009) (163)
- Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia. (2003) (154)
- Characterization of endogenous human promyelocytic leukemia isoforms. (2006) (153)
- A sumoylation site in PML/RARA is essential for leukemic transformation. (2005) (142)
- New therapeutic approaches for adult T-cell leukaemia. (2004) (139)
- Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine. (2014) (135)
- PML nuclear bodies: from architecture to function. (2018) (131)
- The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies (1996) (130)
- Curing APL through PML/RARA degradation by As2O3. (2012) (129)
- TP53 Status and Response to Chemotherapy in Breast Cancer (2008) (126)
- Phase II trial of arsenic trioxide and alpha interferon in patients with relapsed/refractory adult T-cell leukemia/lymphoma. (2004) (126)
- Revisiting the differentiation paradigm in acute promyelocytic leukemia. (2011) (119)
- Resistance to therapy in acute promyelocytic leukemia. (2014) (118)
- PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers (2019) (118)
- Nuclear targeting of incoming human foamy virus Gag proteins involves a centriolar step (1997) (116)
- Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies. (1997) (116)
- PML‐containing nuclear bodies: Their spatial distribution in relation to other nuclear components (1996) (115)
- Targeting of incoming retroviral Gag to the centrosome involves a direct interaction with the dynein light chain 8 (2003) (114)
- A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia. (1992) (114)
- RXR is an essential component of the oncogenic PML/RARA complex in vivo. (2007) (111)
- Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation. (2006) (110)
- Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells. (2015) (109)
- Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor. (2005) (108)
- Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells. (2003) (107)
- In Vivo Activation of cAMP Signaling Induces Growth Arrest and Differentiation in Acute Promyelocytic Leukemia (2002) (106)
- Distinct tumor protein p53 mutants in breast cancer subgroups (2013) (102)
- Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure (2009) (97)
- Adenovirus infection induces rearrangements in the intranuclear distribution of the nuclear body-associated PML protein. (1995) (97)
- Isolation and Characterization of an Equine Foamy Virus (2000) (95)
- Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics. (2010) (92)
- Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15 (2013) (92)
- Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia (2010) (92)
- Differentiation therapy revisited (2017) (88)
- PML nuclear bodies: Assembly and oxidative stress-sensitive sumoylation (2014) (83)
- A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells (2007) (80)
- Critical Involvement of the ATM-Dependent DNA Damage Response in the Apoptotic Demise of HIV-1-Elicited Syncytia (2008) (79)
- Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies (2013) (78)
- All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells. (1991) (77)
- Arsenic-interferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation. (2000) (75)
- Chromatin Tethering of Incoming Foamy Virus by the Structural Gag Protein (2008) (74)
- LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies. (1996) (71)
- Two populations of neuronal intranuclear inclusions in SCA7 differ in size and promyelocytic leukaemia protein content. (2002) (69)
- Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors. (1995) (68)
- Donor-derived oral squamous cell carcinoma after allogeneic bone marrow transplantation. (2007) (67)
- Human T-cell lymphotropic virus type 1-transformed cells induce angiogenesis and establish functional gap junctions with endothelial cells. (2002) (65)
- Mycosis fungoides and Sezary syndrome are not associated with HTLV‐I infection: an international study (1997) (64)
- PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence (2015) (63)
- HIV‐1 infection of primary effusion lymphoma cell line triggers Kaposi's sarcoma‐associated herpesvirus (KSHV) reactivation (2002) (61)
- ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation. (2015) (59)
- Distinct p53 Gene Signatures Are Needed to Predict Prognosis and Response to Chemotherapy in ER-Positive and ER-Negative Breast Cancers (2011) (58)
- PML is a ROS sensor activating p53 upon oxidative stress (2017) (58)
- Human T-Cell Lymphotropic Virus Type I-Infected Cells Extravasate through the Endothelial Barrier by a Local Angiogenesis-Like Mechanism (2004) (58)
- Candidate Luminal B Breast Cancer Genes Identified by Genome, Gene Expression and DNA Methylation Profiling (2014) (57)
- Dimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization. (2006) (57)
- Adenovirus protein IX sequesters host‐cell promyelocytic leukaemia protein and contributes to efficient viral proliferation (2003) (56)
- Involvement of a spliced and defective human foamy virus in the establishment of chronic infection (1995) (56)
- Immunohistochemical and molecular analyses of HER2 status in breast cancers are highly concordant and complementary approaches (2011) (55)
- Impairment of Human Immunodeficiency Virus Type-1 Integrase SUMOylation Correlates with an Early Replication Defect* (2011) (55)
- TP53 mutation‐correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53‐mutated breast cancers (2014) (54)
- RARα-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia (2007) (54)
- Association between a high number of isolated lymph nodes in T1 to T4 N0M0 colorectal cancer and the microsatellite instability phenotype. (2010) (54)
- RING tetramerization is required for nuclear body biogenesis and PML sumoylation (2018) (53)
- Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome (2011) (53)
- Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication (2014) (53)
- PML nuclear bodies: regulation, function and therapeutic perspectives (2014) (52)
- The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells. (1994) (50)
- Cyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers. (2010) (48)
- Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress (2020) (48)
- Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity. (2007) (46)
- Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. (2019) (45)
- p53 dependent cell‐cycle arrest triggered by chemotherapy in xenografted breast tumors (2009) (43)
- A Meta-Analysis of the Relationship between FGFR3 and TP53 Mutations in Bladder Cancer (2012) (43)
- The drug-induced degradation of oncoproteins: an unexpected Achilles' heel of cancer cells? (2011) (42)
- Centrosomal Latency of Incoming Foamy Viruses in Resting Cells (2007) (41)
- HTLV-1 provirus and mycosis fungoides. (1993) (41)
- Animal models on HTLV-1 and related viruses: what did we learn? (2012) (39)
- Protease-Dependent Uncoating of a Complex Retrovirus (2005) (39)
- The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma (2013) (39)
- Controversies in Targeted Therapy of Adult T Cell Leukemia/Lymphoma: ON Target or OFF Target Effects? (2011) (39)
- DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish (2015) (39)
- An Evolutionarily Conserved Splice Generates a Secreted Env-Bet Fusion Protein during Human Foamy Virus Infection (1998) (38)
- Retinoic acid and arsenic: towards oncogene-targeted treatments of acute promyelocytic leukaemia. (1997) (37)
- Acute promyelocytic leukemia: new issues on pathogenesis and treatment response. (2007) (37)
- Human Foamy Virus Capsid Formation Requires an Interaction Domain in the N Terminus of Gag (2001) (36)
- PML, SUMOylation, and Senescence (2013) (35)
- Altered retinoic acid receptors. (1996) (33)
- Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392. (2014) (32)
- Effective targeting of chronic myeloid leukemia initiating activity with the combination of arsenic trioxide and interferon alpha (2013) (32)
- Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation. (2014) (32)
- Centrosomal pre-integration latency of HIV-1 in quiescent cells (2007) (31)
- The PML and PML/RARalpha domains: from autoimmunity to molecular oncology and from retinoic acid to arsenic. (1996) (31)
- Human T‐cell‐leukemia virus type I in post‐transfusional spastic paraparesis: Complete proviral sequence from uncultured blood cells (1995) (30)
- Evidence of chromosome regions and gene involvement in inflammatory breast cancer (2002) (30)
- FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias. (2019) (29)
- Arsenic trioxide and acute promyelocytic leukemia: clinical and biological. (2007) (28)
- Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia (2018) (28)
- Retinoic acid dramatically enhances the arsenic trioxide-induced cell cycle arrest and apoptosis in retinoic acid receptor alpha-positive human T-cell lymphotropic virus type-I-transformed cells. (2001) (27)
- Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation. (2018) (27)
- Sequestration of PML and Sp100 proteins in an intranuclear viral structure during herpes simplex virus type 1 infection. (1995) (27)
- Identification of a three-gene expression signature of early recurrence in non-muscle-invasive urothelial cell carcinoma of the bladder. (2012) (25)
- Long-term survival of advanced triple-negative breast cancers with a dose-intense cyclophosphamide/anthracycline neoadjuvant regimen (2014) (24)
- The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia (2018) (24)
- Promyelocytic Leukemia Protein (PML) Controls Listeria monocytogenes Infection (2017) (23)
- Classic and Variants APLs, as Viewed from a Therapy Response (2020) (23)
- Sumoylation of CCAAT/enhancer-binding protein α promotes the biased primitive hematopoiesis of zebrafish. (2011) (23)
- Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy (2021) (22)
- Recent insights into the biology of the human foamy virus. (1995) (21)
- Retinoic acid plus arsenic trioxide, the ultimate panacea for acute promyelocytic leukemia? (2013) (19)
- Opinion: how patients have benefited from mouse models of acute promyelocytic leukaemia. (2005) (19)
- Limited small cell lung cancer: possible prognostic impact of initial chemotherapy doses. (1989) (19)
- 8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation (2013) (19)
- Combination of chemotherapy and radiotherapy in limited small cell lung carcinoma: results of alternating schedule in 109 patients. (1988) (18)
- TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy (2019) (18)
- Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML (2021) (17)
- Prognostic value of loss of heterozygosity at chromosome 9p in non-muscle-invasive bladder cancer. (2010) (16)
- Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation (2015) (16)
- Human skin carcinoma arising from kidney transplant-derived tumor cells. (2013) (15)
- Responding to allegations of scientific misconduct (2000) (15)
- CCAAT/enhancer-binding protein α is required for hepatic outgrowth via the p53 pathway in zebrafish (2015) (14)
- Sumoylation of CCAAT/enhancer-binding protein α is implicated in hematopoietic stem/progenitor cell development through regulating runx1 in zebrafish (2015) (13)
- Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia. (2018) (13)
- Arsenic trioxide (As2O3) as a maintenance therapy for adult T cell leukemia/lymphoma (2020) (13)
- GATA5 SUMOylation is indispensable for zebrafish cardiac development. (2017) (13)
- A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells (2019) (12)
- JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML (2020) (12)
- Detection of Protein SUMOylation In Situ by Proximity Ligation Assays. (2016) (12)
- Sumoylation in Physiology, Pathology and Therapy (2022) (11)
- p53 as an Effector or Inhibitor of Therapy Response. (2015) (10)
- The efficacy of combined therapy of arsenic trioxide and alpha interferon in human T-cell leukemia virus type-1-infected squirrel monkeys (Saimiri sciureus). (2006) (10)
- Changes in allelic imbalances in locally advanced breast cancers after chemotherapy (2007) (9)
- Functional TP53 mutations have no impact on response to cytotoxic agents in metastatic colon cancer. (2015) (9)
- Retinoids in haematology : a timely revival? (2021) (8)
- A new oncoprotein catabolism pathway. (2010) (8)
- Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells (2021) (8)
- Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia (2022) (7)
- A Promyelocytic Leukemia Protein–Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma (2016) (7)
- Prevalence and spectrum of microsatellite alterations in nonmuscle invasive bladder cancers. (2011) (7)
- Interferon regulatory factor 2 binding protein 2b regulates neutrophil versus macrophage fate during zebrafish definitive myelopoiesis (2019) (7)
- How animal models of leukaemias have already benefited patients (2013) (7)
- Hematopoietic stem cells burn fat to prevent exhaustion. (2012) (7)
- A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c-acute myeloid leukemia. (2021) (6)
- Promyelocytic Leukemia Protein, a Protein at the Crossroad of Oxidative Stress and Metabolism. (2017) (6)
- A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA (2021) (6)
- Molecular biology of the human foamy virus. (1996) (6)
- Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia. (2023) (5)
- Experience of the Institut Gustave-Roussy in alternating radiotherapy and chemotherapy schedules as induction treatment in limited small-cell lung cancer. (1988) (5)
- The DNA Binding Property of PML/RARA but Not the Integrity of PML Nuclear Bodies Is Indispensable for Leukemic Transformation (2014) (4)
- Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway (2020) (4)
- PML/RARA destabilization by hyperthermia: a new model for oncogenic fusion protein degradation? (2021) (4)
- Lessons taught by acute promyelocytic leukemia cure. (2015) (4)
- Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML) (2021) (4)
- [RXR, a key member of the oncogenic complex in acute promyelocytic leukemia]. (2011) (3)
- Primitive macrophages are dispensable for HSPC mobilization and definitive hematopoiesis. (2019) (3)
- Comparison of TP53 mutations screening by functional assay of separated allele in yeast and next-generation sequencing in myelodysplastic syndromes. (2015) (3)
- Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish (2021) (3)
- SMAD4-related Familial Juvenile Polyposis Syndrome with Colon Cancer. (2004) (3)
- Publisher Correction: RING tetramerization is required for nuclear body biogenesis and PML sumoylation (2018) (2)
- Tax as a therapeutic target in ATL (2015) (2)
- Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication (2022) (2)
- [Exquisite sensitivity of TP53 mutant breast cancers to dose-dense chemotherapy]. (2007) (2)
- The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” micro-environment in patients with adult T-cell leukemia lymphoma (2013) (2)
- Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells (2022) (2)
- [Effect of PML and PML-RAR on the transactivation properties and subcellular localization of steroid hormone receptors]. (1996) (2)
- HIV-1 integrase SUMOylation and viral replication (2011) (1)
- Tax as a therapeutic target in ATL (2015) (1)
- Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway (2020) (1)
- Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15 (2013) (1)
- PML/RARα Destabilization by Hyperthermia: A New Model for Oncogenic Fusion Protein Degradation? (2021) (1)
- [Biological parameters of the efficiency of retinoic acid in acute leukemia]. (1991) (1)
- Acute promyelocytic leukemia, the retinoid paradox (1992) (1)
- Unbiased in vivo exploration of nuclear bodies-enhanced sumoylation reveals that PML orchestrates embryonic stem cell fate (2021) (1)
- [Arsenic and retinoic acid, toward targeted treatments of acute promyelocytic anemia?]. (1998) (1)
- The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” micro-environment in patients with adult T-cell leukemia lymphoma (2014) (0)
- Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival (2023) (0)
- [Tissue microdissection: application to the study of cancer of the breast]. (1999) (0)
- Zbtb14 regulates monocyte and macrophage development through inhibiting pu.1 expression in zebrafish (2022) (0)
- Publisher Correction: RING tetramerization is required for nuclear body biogenesis and PML sumoylation (2018) (0)
- Author Correction: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells (2023) (0)
- [Acute promyelocytic leukemia: molecular aspects]. (1995) (0)
- The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma (2013) (0)
- Tax as a therapeutic target in ATL (2015) (0)
- TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy (2019) (0)
- Tax as a therapeutic target in ATL (2015) (0)
- 1017 – INVESTIGATING THE MECHANISMS OF IFNALPHA THERAPY IN JAK2V617F AND CALR MUTATED MYELOPROLIFERATIVE NEOPLASMS (2020) (0)
- Obituary for Guy de Thé (2015) (0)
- Microdissection and breast cancer. (2000) (0)
- [Arsenic: The gold standard for acute promyelocytic leukaemia with FLT3-ITD mutation]. (2021) (0)
- [Arsenic and retinoic acid, towards targeted treatments of acute promyelocytic leukemia?]. (1998) (0)
- Ypel5 regulates liver development and function in zebrafish. (2023) (0)
- Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia (2015) (0)
- An exciting RXRA mutant revives interest in retinoids for acute myeloid leukemia (2021) (0)
- Clinical Trials and Observations (2006) (0)
- Tax as a therapeutic target in ATL (2015) (0)
- Tax as a therapeutic target in ATL (2015) (0)
- Arsenic (2022) (0)
- Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia (2015) (0)
- Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients (2021) (0)
- In APL, noncoding mutations and SNP converge on WT1. (2022) (0)
- Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia (2018) (0)
- RING tetramerization is required for nuclear body biogenesis and PML sumoylation (2018) (0)
- Prognostic value of initial chemotherapy doses in limited small cell lung cancer. (1988) (0)
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