Ichiro Azuma
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Ichiro Azuma's Degrees
- PhD Immunology University of Tokyo
- Masters Biology University of Tokyo
- Bachelors Biology University of Tokyo
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(Suggest an Edit or Addition)Ichiro Azuma's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors (2000) (445)
- Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside-Rg3, of red ginseng. (1995) (389)
- Immunological activity of chitin and its derivatives. (1984) (376)
- Role of aminopeptidase N (CD13) in tumor‐cell invasion and extracellular matrix degradation (1993) (344)
- Biologically active components from mycobacterial cell walls. I. Isolation and composition of cell wall skeleton and component P3. (1974) (221)
- Inhibition of tumor angiogenesis and metastasis by a saponin of Panax ginseng, ginsenoside-Rb2. (1994) (219)
- Bovine Lactoferrin and Lactoferricin, a Peptide Derived from Bovine Lactoferrin, Inhibit Tumor Metastasis in Mice (1997) (194)
- Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by Mycobacterium bovis Bacillus Calmette-Guérin Peptidoglycan (2003) (175)
- Stimulation of cytokine production in mice using deacetylated chitin. (1986) (154)
- Adjuvant activity of chitin derivatives in mice and guinea-pigs. (1985) (153)
- Biochemical Studies on the Thermal Dimorphism of Paracoccidioides brasiliensis (1972) (145)
- Apoptosis in human leukemic cells induced by lactoferricin, a bovine milk protein-derived peptide: involvement of reactive oxygen species. (1997) (145)
- Zinc suppresses Th17 development via inhibition of STAT3 activation. (2010) (144)
- Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules. (1989) (134)
- Biologically active components from mycobacterial cell walls. II. Suppression and regression of strain-2 guinea pig hepatoma. (1974) (128)
- Macrophage activation with multi-porous beads prepared from partially deacetylated chitin. (1986) (126)
- Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13 (1995) (122)
- Inhibition by sulfated chitin derivatives of invasion through extracellular matrix and enzymatic degradation by metastatic melanoma cells. (1990) (120)
- Adjuvant activity of mycobacterial fractions: adjuvant activity of synthetic N-acetylmuramyl-dipeptide and the related compounds (1976) (114)
- Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer. (2003) (114)
- Bioactive chitin derivatives. Activation of mouse-peritoneal macrophages by O-(carboxymethyl)chitins. (1986) (114)
- Development of immunoadjuvants for immunotherapy of cancer. (2001) (113)
- Adjuvant-Mediated Tumor Regression and Tumor-Specific Cytotoxic Response Are Impaired in MyD88-Deficient Mice (2004) (110)
- Characterization of the nucleocapsid protein of Hantaan virus strain 76-118 using monoclonal antibodies. (1996) (103)
- Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation1 (2005) (100)
- Occurrence of N-glycolylmuramic acid in bacterial cell walls. A preliminary survey. (1970) (90)
- Mycobacterium bovis BCG Cell Wall-Specific Differentially Expressed Genes Identified by Differential Display and cDNA Subtraction in Human Macrophages (2004) (87)
- Inhibition of Tumor Cell Invasion by Ubenimex (Bestatin) in vitro (1989) (86)
- Structures and biological activities of peptidoglycans of Listeria monocytogenes and Propionibacterium acnes. (1982) (82)
- Inhibition of tumor-induced angiogenesis by sulfated chitin derivatives. (1991) (81)
- Lectins isolated from Korean mistletoe (Viscum album coloratum) induce apoptosis in tumor cells. (1999) (81)
- High sensitivity of human melanoma cell lines to the growth inhibitory activity of mycoplasmal arginine deiminase in vitro (1992) (80)
- Biologically active components from mycobacterial cell walls. IV. Protection of mice against aerosol infection with virulent mycobacterium tuberculosis. (1975) (79)
- Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences. (1989) (79)
- Structural studies on teichoic acids in cell walls of several serotypes of Listeria monocytogenes. (1986) (78)
- Structural and immunochemical studies on D-arabino-D-mannans and D-mannans of Mycobacterium tuberculosis and other Mycobacterium species. (1977) (77)
- Immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets. (1974) (75)
- Prophylactic effect of Korean mistletoe (Viscum album coloratum) extract on tumor metastasis is mediated by enhancement of NK cell activity. (1998) (75)
- Enhancement of Immunologic Tumor Regression by Intratumoral Administration of Dendritic Cells in Combination with Cryoablative Tumor Pretreatment and Bacillus Calmette-Guerin Cell Wall Skeleton Stimulation (2006) (74)
- Adjuvant effect of cord factor, a mycobacterial lipid (1976) (71)
- Adjuvant and antitumor activities of Nocardia cell-wall skeletons. (1976) (68)
- The inhibition of murine lung metastasis by synthetic polypeptides [poly(arg-gly-asp) and poly(tyr-ile-gly-ser-arg)] with a core sequence of cell adhesion molecules. (1989) (68)
- Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice. (1998) (68)
- Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN. (1997) (68)
- Stimulation of nonspecific resistance to infection induced by 6-O-acyl muramyl dipeptide analogs in mice (1981) (67)
- Adjuvant immunotherapy of lung cancer with BCG cell wall skeleton (BCG‐CWS) (1979) (65)
- Structure and immunological properties of D-arabino-D-galactans isolated from cell walls of Mycobacterium species. (1974) (65)
- Inhibitory effect of Korean mistletoe (Viscum album coloratum) extract on tumour angiogenesis and metastasis of haematogenous and non-haematogenous tumour cells in mice. (1995) (63)
- Stimulation of non-specific host resistance against Sendai virus and Escherichia coli infections by chitin derivatives in mice. (1987) (61)
- Inhibitory Effect of Chitin Heparinoids on the Lung Metastasis of B16‐BL6 Melanoma (1989) (61)
- IMMUNOTHERAPY OF CANCER WITH CELL WALL SKELETON OF MYCOBACTERIUM BOVIS‐BACILLUS CALMETTE‐GUÉRIN: EXPERIMENTAL AND CLINICAL RESULTS (1976) (61)
- Nonspecific adjuvant immunotherapy of lung cancer with cell wall skeleton of Mycobacterium bovis Bacillus Calmette-Guérin. (1979) (60)
- Structural and immunochemical studies of teichoic acid of Listeria monocytogenes. (1983) (60)
- Synthesis of long chain fatty acid esters of N-acetylmuramyl-L-alanyl-D-isoglutamine in relation to antitumor activity (1979) (60)
- Activation of rainbow trout (Oncorhynchus mykiss) phagocytes by muramyl dipeptide. (1993) (57)
- Adjuvanticity of mycobacterial cell walls. (1971) (57)
- Stimulation of nonspecific resistance to infection induced by muramyl dipeptide analogs substituted in the gamma-carboxyl group and evaluation of N alpha-muramyl dipeptide-N epsilon-stearoyllysine (1983) (55)
- New model of a synthetic adjuvant, N-acetylmuramyl-L-alanyl-D-isoglutamine- induced arthritis: clinical and histologic studies in athymic nude and euthymic rats. (1982) (54)
- Functional role of sialyl Lewis X and fibronectin‐derived RGDS peptide analogue on tumor‐cell arrest in lungs followed by extravasation (1996) (54)
- Studies on the firmly bound lipids of human tubercle bacillus (1962) (53)
- Association of macrophage activation with antitumor effect on rat syngeneic fibrosarcoma by Nocardia rubra cell wall skeleton. (1979) (52)
- Interferon gamma-producing ability in blood lymphocytes of patients with lung cancer through activation of the innate immune system by BCG cell wall skeleton. (2001) (51)
- Synthetic immunoadjuvants: application to non-specific host stimulation and potentiation of vaccine immunogenicity. (1992) (50)
- Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds (1978) (50)
- Biologically active components from mycobacterial cell walls. V. Granuloma formation in mouse lungs and guinea pig skin. (1975) (48)
- Chemical and ultrastructural studies on the cell walls of the yeastlike and mycelial forms of Histoplasma capsulatum (1974) (48)
- Anti-metastatic and anti-invasive effects of polymeric Arg-Gly-Asp (RGD) peptide, poly(RGD), and its analogues. (1990) (48)
- Immunological aspects of chitin and chitin derivatives administered to animals. (1999) (48)
- Fractionation of mycobacterial cell wall. Isolation of arabinose mycolate and arabinogalactan from cell wall fraction of Mycobacterium tuberculosis strain Aoyama B (1968) (47)
- Effect of multiporous microspheres derived from chitin and partially deacetylated chitin on the activation of mouse peritoneal macrophages. (1987) (46)
- Isolation and mass spectrometric identification of the peptide subunits of mycobacterial cell walls. (1970) (46)
- Recombinant human granulocyte colony‐stimulating factor inhibits the metastasis of hematogenous and non‐hematogenous tumors in mice (1991) (45)
- Antitumor activity of cell-wall skeletons and peptidoglycolipids of mycobacteria and related microörganisms in mice and rabbits. (1974) (45)
- Establishment of a SCID mouse model having circulating human red blood cells and a possible growth of Plasmodium falciparum in the mouse. (1995) (45)
- WT1 peptide vaccination combined with BCG-CWS is more efficient for tumor eradication than WT1 peptide vaccination alone (2004) (44)
- Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album colaratum). (2001) (43)
- Inhibition of Lung Metastasis by Synthetic and Recombinant Fragments of Human Fibronectin with Functional Domains (1990) (43)
- MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide, inhibits the metastasis of haematogenous and non-haematogenous tumours in mice. (1994) (42)
- Inhibition of tumor‐induced angiogenesis by the administration of recombinant interferon‐γ followed by a synthetic lipid‐a subunit analogue (GLA‐60) (1992) (42)
- Induction of tumoricidal macrophages and production of cytokines by synthetic muramyl dipeptide analogues. (1988) (41)
- Inhibition of tumor angiogenesis by a synthetic cell-adhesive polypeptide containing the Arg-Gly-Asp (RGD) sequence of fibronectin, poly(RGD). (1990) (40)
- Isolation and Characterization of Arabinose Mycolate from Firmly Bound Lipids of Mycobacteria (1969) (40)
- Immuno-friendly use of BCG-cell wall skeleton remarkably improves the survival rate of various cancer patients (1998) (39)
- Adjuvant activities of quinonyl-N-acetyl muramyl dipeptides in mice and guinea pigs (1981) (39)
- Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine. (1998) (38)
- The adjuvant activity of synthetic N-acetylmuramyl-dipeptide: evidence of initial target cells for the adjuvant activity. (1979) (38)
- Structural studies on lipoteichoic acids from four Listeria strains (1986) (37)
- Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine. (1998) (37)
- Randomly controlled study of chemotherapy versus chemoimmunotherapy in postoperative lung cancer patients. (1983) (37)
- Induction of resistance to tuberculosis in mice with defined components of mycobacteria and with some unrelated materials. (1982) (36)
- Theileria sergenti proliferates in SCID mice with bovine erythrocyte transfusion. (1992) (36)
- Chemical Compositions of Cell Walls and Polysaccharide Fractions of Spirochetes (1984) (36)
- Protective immunity of Hantaan virus nucleocapsid and envelope protein studied using baculovirus-expressed proteins (2005) (36)
- Lethal and adjuvant activities of cord factor (trehalose-6,6'-dimycolate) and synthetic analogs in mice. (1985) (35)
- Mycobacterial cell wall components in tumor suppression and regression. (1973) (35)
- Inhibition of tumor invasion and extracellular matrix degradation by ubenimex (bestatin) (2004) (35)
- Adjuvant Activity of Mycobacterial Fractions (1974) (34)
- Chemical and immunological properties of galactomannans obtained from Histoplasma duboisii, Histoplasma capsulatum, Paracoccidioides brasiliensis and Blasomyces dermatitidis (1974) (34)
- Inhibitory effect of trehalose dimycolate (TDM) and its stereoisometric derivatives, trehalose dicorynomycolates (TDCMs), with low toxicity on lung metastasis of tumour cells in mice. (1999) (33)
- Structural studies of cell wall polysaccharides from Bifidobacterium breve YIT 4010 and related Bifidobacterium species. (1987) (33)
- Mitogenic activity of the cell walls of mycobacteria, nocardia, corynebacteria and anaerobic coryneforms. (1976) (32)
- Killing of tumor cells in vitro by macrophages from mice given injections of squalene-treated cell wall skeleton of Nocardia rubra. (1981) (32)
- Stimulation of chemiluminescence and resistance against aerogenic influenza virus infection by synthetic muramyl dipeptide combined with trehalose dimycolate (1984) (32)
- Chemical and Immunological Studies on Mycobacterial Polysaccharides I. Purification and Properties of Polysaccharides from Human Tubercle Bacilli (1968) (32)
- Adjuvant activity of synthetic N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds on cell-mediated cytotoxicity in syngeneic mice. (1977) (32)
- 6-O-carboxymethyl-chitin (CM-chitin) as a drug carrier. (1990) (31)
- Production of recombinant hantavirus nucleocapsid protein expressed in silkworm larvae and its use as a diagnostic antigen in detecting antibodies in serum from infected rats. (1995) (31)
- Review: inducer of cytokines in vivo: overview of field and romurtide experience. (1992) (31)
- Efficient syntheses of a series of trehalose dimycolate (TDM)/trehalose dicorynomycolate (TDCM) analogues and their interleukin-6 level enhancement activity in mice sera. (2007) (31)
- Stimulation of Nonspecific Host Resistance to Infection Induced by Muramyldipeptides (1981) (30)
- Structural study on teichoic acids of Listeria monocytogenes types 4a and 4d. (1985) (30)
- Influence of fibroblasts on the invasion and migration of highly or weakly metastatic b16 melanoma cells (1994) (30)
- Effect of muramyl dipeptide and its stearoyl derivatives on resistance to Sendai virus infection in mice. (1985) (30)
- Protective activity of recombinant cytokines against Sendai virus and herpes simplex virus (HSV) infections in mice. (1989) (29)
- Suppression of Sendai virus growth by treatment with Nα-acetylmuramyl-l-alanyl-d-isoglutaminyl-Nϵ-stearoyl-l-lysine in mice (1987) (29)
- Role of the heparin-binding domain of chimeric peptides derived from fibronectin in cell spreading and motility. (1995) (29)
- Novel quinonyl derivatives of muramyl dipeptide possessing potent antitumor activity. (1979) (29)
- Anti-tumour activity of Lactobacillus casei on lewis lung carcinoma and line-10 hepatoma in syngeneic mice and guinea pigs (2004) (29)
- Immunotherapy of cancer: tumor suppression and regression by cell walls of Mycobacterium phlei attached to oil droplets. (1975) (28)
- Synthesis of 6-O-Mycoloyl-Nacetylmuramyl-L-alanyl-D-isoglutamine with Antitumor Activity (1978) (28)
- Regulation of antibody response in different immunoglobulin classes. VI. Selective suppression of IgE response by administration of antigen-conjugated muramylpeptides. (1978) (28)
- Adjuvant activity of purified peptidoglycan of Listeria monocytogenes in mice and guinea pigs (1982) (27)
- Effect of Paraquat Dichloride on Some Metabolic and Enzyme Parameters of Clarias gariepinus (2011) (27)
- Vaccination of tumor cells transfected with the B7‐1 (CD80) gene induces the anti‐metastatic effect and tumor immunity in mice (1996) (27)
- Comparison of Virulence between Seoul Virus Strain SR‐11 and Hantaan Virus Strain 76–118 of Hantaviruses in Newborn Mice (1993) (26)
- Adjuvant activity of carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs (1981) (26)
- Adjuvant and anti tumor activities of nocardia rubra cell wall skeletons (1976) (26)
- Antitumor activity of squalene-treated cell-wall skeleton of Nocardia rubra in mice. (1978) (26)
- Immunological Activity of Chitin Derivatives (1986) (26)
- Antimetastatic Activity of Polymeric RGDT Peptides Conjugated with Poly(ethylene glycol) (1993) (26)
- Tumor growth inhibitory activity of a lymphocyte blastogenesis inhibitory factor. (1990) (25)
- Chemical and immunological studies on the cell walls of Propionibacterium acnes strain C7 and Corynebacterium parvum ATCC 11829. (1975) (25)
- Antimetastatic Effect by Anti‐adhesion Therapy with Cell‐adhesive Peptide of Fibronectin in Combination with Anticancer Drugs (1993) (25)
- Transfusion with xenogeneic erythrocytes into SCID mice and their clearance from the circulation. (1994) (24)
- CHEMICAL AND IMMUNOLOGICAL STUDIES ON PEPTIDES AND POLYSACCHARIDES FROM TUBERCLE BACILLI (1968) (24)
- Synthesis of Muramyl Dipeptide Analogs with Enhanced Adjuvant Activity (1980) (24)
- Effects of muramyl dipeptide derivatives as adjuvants on the induction of antibody response to recombinant hepatitis B surface antigen. (1995) (24)
- Adjuvant activity of N-acetyl muramyl dipeptides for the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs. (1980) (23)
- Effect of Nα-acetylmuramyl-l-alanyl-d-isoglutaminyl-Nϵ-stearoyl-l-lysine on resistance to herpes simplex virus type-1 infection in cyclophosphamide-treated mice (1989) (23)
- Adjuvant activity of mycobacterial fractions. I. Purification and in vivo adjuvant activity of cell wall skeletons of Mycobacterium bovis BCG, Nocardia asteroides 131 and Corynebacterium diphtheriae PW8. (1975) (23)
- Modulation of haptotactic migration of metastatic melanoma cells by the interaction between heparin and heparin-binding domain of fibronectin. (1990) (23)
- Inhibition of Tumor Cell Arrest in Lungs by Antimetastatic Chitin Heparinoid (1990) (22)
- Characterization of the invasive and metastatic phenotype in human renal cell carcinoma (1991) (22)
- Anti-viral activity of sulfated chitin derivatives against Friend murine leukaemia and herpes simplex type-1 viruses. (1993) (22)
- Antimetastatic effect of Lactobacillus casei YIT9018 (LC 9018) on a highly metastatic variant of B16 melanoma in C57BL/6J mice (2004) (22)
- Recombinant Fusion Polypeptide with Cell‐ and Heparin‐binding Domains of Fibronectin Inhibits Liver Metastasis of L5178Y‐ML25 Lymphoma Cells (1991) (22)
- Persistence of protein, carbohydrate and was components of tubercle bacilli in dermal BCG lesions. (1981) (21)
- Adjuvant and antitumour activities of synthetic lipid A analogues. (1986) (21)
- Antimetastatic activities of synthetic Arg-Gly-Asp-Ser (RGDS) and Arg-Leu-Asp-Ser (RLDS) peptide analogues and their inhibitory mechanisms. (1995) (21)
- Biochemical and immunological studies on Aspergillus (1969) (21)
- Effect of MDP-Lys(L18) as a mucosal immunoadjuvant on protection of mucosal infections by Sendai virus and rotavirus. (1996) (21)
- Inhibitory Effect of Recombinant Fibronectin Polypeptides on the Adhesion of Liver‐metastatic Lymphoma Cells to Hepatic Sinusoidal Endothelial Cells and Tumor Invasion (1994) (20)
- Cytostatic activity of peripheral blood monocytes against bronchogenic carcinoma cells in patients with lung cancer. (1979) (20)
- Adjuvant activity of mycobacterial fractions. III. Adjuvant effect of cell wall of Mycobacterium bovis BCG on cell-mediated cytotoxicity in mice. (1975) (20)
- Suppression of BCG cell wall-induced delayed-type hypersensitivity by pretreatment with killed BCG: induction of nonspecific suppressor T cells by the adjuvant portion (MDP) and of specific suppressor T cells by the antigen portion (TAP). (1984) (20)
- Structure of acidic polysaccharide from cell wall of Propionibacterium acnes strain C7. (1985) (19)
- Identification and purification of arginine deiminase that originated from Mycoplasma arginini (1990) (19)
- Adjuvant activity of 6-O-mycoloyl derivatives of N-acetylmuramyl-L-seryl-D-isoglutamine and related compounds in mice and guinea pigs (1979) (19)
- A sulfated chitin inhibits hemagglutination by Theileria sergenti merozoites (1999) (19)
- Inhibitory effect of a synthetic polypeptide, poly(Tyr-Ile-Gly-Ser-Arg), on the metastatic formation of malignant tumour cells. (1989) (19)
- A cytokine, lymphocyte blastogenesis inhibitory factor (LBIF), arrests mitogen‐stimulated T lymphocytes at early G1 phase with no influence on interleukin 2 production and interleukin 2 receptor light chain expression (1989) (19)
- Antimetastatic activity of neocarzinostatin incorporated into controlled release gels of CM-chitin (1992) (19)
- Elevated argininosuccinate synthetase activity in adult T leukemia cell lines. (1990) (19)
- Syntheses of Trehalose Monomycolate and Related Compounds, and Their Lethal Toxicity and Adjuvant Activity (1986) (19)
- Synthesis and biological activities of N-acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine and some of its lipophilic derivatives. (1983) (18)
- Chemical studies on the cell walls of Leptorspira biflexa strain Urawa and Treponema pallidum strain Reiter. (1975) (18)
- Antitumor activity of Nocardia cell wall skeleton preparations in transplantable tumors in syngeneic mice and patients with malignant pleurisy (1978) (18)
- Persistent infection of MT-4 cells by human immunodeficiency virus type 1 becomes increasingly likely with in vitro serial passage of wild-type but not nef mutant virus. (1994) (18)
- Synthesis, and the Adjuvant and Tumor-Suppressive Activities of Quinonyl Muramyl Dipeptides (1984) (18)
- The conjugation of RGDS peptide with CM-chitin augments the peptide-mediated inhibition of tumor metastasis (1993) (18)
- Relationship of anti-tuberculous protection to lung granuloma produced by intravenous injection of synthetic 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine with or without specific antigens. (1982) (18)
- Suppression of BCG cell wall induced delayed-type hypersensitivity by BCG pre-treatment. I. Induction of adherent suppressor cells by live BCG injection and their characterization. (1981) (18)
- A novel synthetic lipid A analog with low endotoxicity, DT-5461, prevents lethal endotoxemia (1995) (18)
- Inhibition of tumor invasion and metastasis by peptidic mimetics of Arg-Gly Asp (RGD) derived from the cell recognition site of fibronectin. (1996) (18)
- Polysaccharides of Mycobacterium bovis Ushi 10, Mycobacterium smegmatis, Mycobacterium phlei, and Atypical Mycobacterium P1 (1970) (18)
- Potentiation of Host Defense Mechanism Against Infection by a Cytokine Inducer, an acyl‐MDP Derivative, MDP‐Lys(L18) (Romurtide) in Mice and Humans (1994) (17)
- Use of low toxicity adjuvants and killed virus to induce protective immunity against the Friend murine leukaemia retrovirus-induced disease. (1992) (17)
- Adjuvant activity of synthetic cell-wall peptidoglycan subunits on monoazobenzenearsonate-N-acetyl-L-tyrosine and bacterial alpha-amylase in guinea pigs. (1976) (17)
- Suppression of tumor growth and regression of established tumor with oil-attached mycobacterial fractions. (1974) (17)
- Adjuvant Activity of 6-Amino-6-Deoxy-Muramyldipeptides and Their Acylamino Derivatives on the Induction of Delayed Hypersensitivity to Azobenzenearsonate-N-Acetyl-l-Tyrosine in Guinea Pigs (1981) (17)
- A new pseudo-peptide of Arg-Gly-Asp (RGD) with inhibitory effect on tumor metastasis and enzymatic degradation of extracellular matrix (2004) (17)
- Muramyl Dipeptide Derivatives with Multiprenylacetyl Group. Synthesis and Immunological Activities (1981) (17)
- Biochemical and immunological studies on Aspergillus. 3. Chemical and immunological properties of glycopeptide obtained from Aspergillus fumigatus. (1971) (17)
- Skin-testing and precipitation antigens from Aspergillus fumigatus for diagnosis of aspergillosis. (1967) (17)
- Inhibitory Effect of Fibronectin and Its Recombinant Polypeptides on the Adhesion of Metastatic Melanoma Cells to Laminin (1991) (17)
- Suppression of autochthonous tumors by mixed implantation with Nocardia rubra cell-wall skeleton and related bacterial fractions. (1978) (17)
- Effect of stearoyl-N-acetylmuramyl-L-alanyl-D-isoglutamine on host resistance to Corynebacterium kutscheri infection in cortisone-treated mice. (1984) (16)
- The equilibrium compositions and conformations of some carbohydrate analogs of N-acetylmuramoyl-l-alanyl-d-isoglutamine as determined by 1H-n.m.r. spectroscopy☆ (1983) (16)
- Stimulation of chemiluminescence by synthetic muramyl dipeptide and analogs (1983) (16)
- Differences in Chemotaxis to Fibronectin in Weakly and Highly Metastatic Tumor Cells (1992) (16)
- Human MD-1 homologue is a BCG-regulated gene product in monocytes: its identification by differential display. (1999) (16)
- Activation of peritoneal macrophages by oil-attached cell-wall skeleton of BCG and Nocardia rubra. (1979) (16)
- Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies (2019) (16)
- Structural-functional relationship of pathogen-associated molecular patterns: lessons from BCG cell wall skeleton and mycoplasma lipoprotein M161Ag. (2002) (16)
- Studies on the toxic substances isolated from mycobacteria. II. Toxic glycolipids of Mycobacterium smegmatis, Mycobacterium phlei and atypical mycobacteria strain No. 6 and No. 22. (1962) (15)
- Immunotherapy of human malignant melanoma with oil-attached BCG cell-wall skeleton. (1975) (15)
- Molecular properties of poly(RGD) and its binding capacities to metastatic melanoma cells. (2009) (15)
- Adjuvant-polyarthritogenicity of cell walls of mycobacteria, nocardia and corynebacteria. (1972) (15)
- Lethal toxicity and adjuvant activities of synthetic TDM and its related compounds in mice. (1989) (15)
- Synthesis of 6-o-mycoloyl-n-acetylmuramyl-l-alanyl- D-isoglutamine with immunoadjuvant activity (1976) (15)
- Chemical and immunological properties of polysaccharides of wax D extracted from Mycobacterium tuberculosis strain Aoyama B (1968) (15)
- Inhibitory effect of BCG cell-wall skeletons (BCG-CWS) emulsified in squalane on tumor growth and metastasis in mice (2002) (14)
- Biological activities of synthetic polypeptides containing a repetitive core sequence (Arg-Gly-Asp) of cell adhesion molecules. (1989) (14)
- Biochemical and Immunological Studies on Aspergillus :I. Chemical and Biological Investigations of Lipopolysaccharide, Protein and Polysaccharide Fractions isolated from Aspergillus fumigatus (1967) (14)
- Adjuvant activity of 6-O-mycoloyl-N-acetylmuramuyl-L-alanyl-D-isoglutamine. (1976) (14)
- Synthesis and immunoadjuvant activities of muramoyl-L-alanyl-D-isoglutamine and some carbohydrate analogs. (1980) (14)
- Cloning and nucleotide sequence of the gene encoding arginine deiminase of Mycoplasma arginini (1990) (14)
- Cell Wall of Mycobacterium lepraemurium Strain Hawaii (1973) (14)
- Macrophage Dependency of T‐lymphocyte Mitogenesis by Nocardia rubra Cell‐Wall Skeleton (1977) (13)
- Enzymatic ADP-ribosylation of benzotriazoles and related triazoles. Difference of glycosidation site between triazoles and indazoles (1989) (13)
- Human immunodeficiency virus type 1 (HIV-1) superinfection of a cell clone converting it from production of defective to infectious HIV-1 is mediated predominantly by CD4 regions other than the major binding site for HIV-1 glycoproteins. (1992) (13)
- Characterization of neutralizing monoclonal antibody escape mutants of Hantaan virus 76118 (1998) (13)
- Synthetic Arg-Gly-Asp-Ser analogues of the cell recognition site of fibronectin that retain antimetastatic and anti-cell adhesive properties. (1993) (13)
- Inhibitory Effect of Antimetastatic Fusion Polypeptide of Human Fibronectin on Tumor Cell Adhesion to Extracellular Matrices (1991) (13)
- Adjuvant and antitumor activities of quinonyl-N-acetylmuramyldipeptides. (1979) (13)
- Comparative study on antitumor effect of cell-wall skeleton of Mycobacterium bovis BCG and Nocardia rubra, with reference to T-cell dependency and independency. (1979) (13)
- Enzymic synthesis and biochemical activity of various indazole adenine dinucleotides. (1985) (13)
- Muramyl dipeptides: prospect for cancer treatments and immunostimulation. (1983) (12)
- Fast protein liquid chromatography of lymphocyte blastogenesis inhibitory factor produced by the human macrophage-like cell line U937. (1988) (12)
- Effect of quinonyl-N-acetyl muramyl dipeptide on immune responses in tumor-bearing mice (1983) (12)
- Immunostimulation in cancer patients. (1983) (12)
- DT‐5461, a New Synthetic Lipid A Analogue, Inhibits Lung and Liver Metastasis of Tumor in Mice (1992) (12)
- [Chemical and immunological studies on mycobacterial polysaccharides]. (1968) (12)
- Inhibition of Tumor‐induced Angiogenesis by a Synthetic Lipid A Analogue with Low Endotoxicity, DT‐5461 (1995) (12)
- In vivo induction of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes and delayed-type hypersensitivity by a 23-amino acid peptide from the highly conserved region in major core protein p24. (1994) (12)
- Inhibition of tumor metastasis by Arg-Gly-Asp-Ser (RGDS) peptide conjugated with sulfated chitin derivative, SCM-chitin-RGDS (1993) (12)
- Synthesis of 1-Thio-N-acetylmuramoyl-L-alanyl-D-isoglutamine Derivatives, and Their Biological Activities. XX (1982) (12)
- Vaccination with WT-1 (Wilms' tumor gene-1) peptide and BCG-CWS in melanoma. (2012) (11)
- ISOLATION OF ARABINOSE MYCOLATE FROM WAX D FRACTION OF HUMAN TYPE TUBERCLE BACILLUS AOYAMA B STRAIN. (1965) (11)
- Two receptor theory in innate immune activation: studies on the receptors for bacillus Culmet Guillen-cell wall skeleton. (2001) (11)
- Possible regulation of intermediate filament proteins by Rho-binding kinases. (1998) (11)
- Chemical synthesis and biological activities of 6,6′-di-O-mycoloyl-β,β- and -α,β-trehalose (1991) (11)
- Biological activities of fundamental, carbohydrate skeleton of lipid A containing amide-linked 3-hydroxytetradecanoic acid. (1981) (11)
- Arginine Deiminase Gene of an AIDS‐Associated Mycoplasma, Mycoplasma incognitus (1992) (11)
- Chemical modification of the C-6 substituent in the carbohydrate moiety of N-acetylmuramoyl-L-alanyl-D-isoglutamine (MDP), and the immunoadjuvant activity. (1983) (11)
- Chemical and immunological studies on polysaccharide antigens of mycobacteria, nocardia and corynebacteria. (1972) (11)
- Viral activation from latency during retrodifferentiation of U937 cells exposed to phorbol ester followed by infection with human immunodeficiency virus type 1. (1995) (10)
- Chemical synthesis and adjuvant activity of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) analogs. (1981) (10)
- Immunostimulants: Now and Tomorrow (1987) (10)
- Chemical modification of the carbohydrate moiety in N-acetylmuramoyl-l-alanyl-d-isoglutamine, and the immunoadjuvant activity☆ (1981) (10)
- Production of interleukin 1 from human monocytes stimulated by synthetic lipid A subunit analogues. (1990) (10)
- Innate Immune Therapy For Cancer (2002) (10)
- Macrophage activation with ubiquinones and their related compounds in mice. (1983) (10)
- Chemical Combination of Biologically Active Derivatives ofN-Acetylmuramoyl Dipeptide and Lipid-A, and Their Biological Activities (1986) (10)
- Antitumor activity of cell-wall skeleton of Propionibacterium acnes C7 in mice and guinea pigs. (1979) (10)
- Biologically active components from mycobacterial cell walls. III. Production of experimental allergic encephalomyelitis in guinea-pigs. (1975) (10)
- Stimulation of host-defense mechanism with synthetic adjuvants and recombinant cytokines against viral infection in mice. (1992) (10)
- Inhibition of Tumor Metastasis by a Synthetic Polymer Containing a Cell-Adhesive RGDS Peptide (1993) (10)
- SYNTHESIS OF 6-O-MYCOLOYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE WITH ANTITUMOR ACTIVITY (1979) (10)
- Prophylactic activity against Sendai virus infection and macrophage activation with lipophilic derivatives of N-acetylglucosaminylmuramyl tri- or tetrapeptides. (1989) (10)
- Suppression by Nocardia rubra cell wall skeleton mammary DNA synthesis, plasma prolactin level, and spontaneous mammary tumorigenesis in mice. (1978) (9)
- B30-MDP, a synthetic muramyl dipeptide derivative for tumour vaccination to enhance antitumour immunity and antimetastatic effect in mice. (1992) (9)
- Structures of Peptidoglycans of Propionibacterium (1983) (9)
- Purification of Polysaccharide Antigen from Leptospira biflexa Strain Urawa (1972) (9)
- Effect of Nocardia and Mycobacterium cell-wall skeleton on autochthonous tumor grafts. (1975) (9)
- Studies on the firmly bound lipids of human tubercle bacillus. I. Isolation of arabinose mycolate. (1962) (9)
- Argininosuccinate synthetase gene expression in leukemias: potential diagnostic marker for blastic crisis of chronic myelocytic leukemia. (1992) (9)
- The mycolic acids of Mycobacterium rhodochrous and Nocardia corallina. (1974) (9)
- Oral application of romurtide, a synthetic muramyl dipeptide derivative, stimulates nonspecific resistance to microbial infections and hematopoiesis in mice. (1996) (9)
- Antitumor activity of peritoneal exudate cells induced by cell-wall skeleton of Mycobacterium bovis BCG. (1978) (9)
- New synthetic immunomodulators combining a 4-O-phosphono-D-glucosamine derivative related to bacterial lipid A with 1-deoxy-N-acetylmuramoyl dipeptide analogs. (1987) (9)
- A new synthetic route to 2-(acylamino)-2-deoxy-alpha-D-glucopyranosyl phosphates, and their endotoxic activity related to the Salmonella-type lipid A. (1981) (9)
- Isolation and purification of anaphylactically active polysaccharide from human tubercle bacilli (1967) (9)
- Monoclonal antibodies to a CD4 peptide derivative which includes the region corresponding to an immunoglobulin CDR3: evidence of the involvement of pre-CDR3-related region in HIV-1 and host cell interaction. (1992) (9)
- Acrylic oligomer for high solid automotive top coating system having excellent acid resistance (1997) (9)
- Activation of macrophages by quinonyl-N-acetylmuramyl dipeptide (1983) (9)
- Experimental immunotherapy of neoplastic pleural effusion with oil-attached BCG cell-wall skeleton in mice. (1976) (8)
- Partial chemical characterization of the cell wall of Nocardia asteroides strain 131. (1973) (8)
- Tolerance to the anti‐metastatic effect of lipopolysaccharide against liver metastasis in mice (1996) (8)
- Inhibition of tumour cell adhesion by anti-metastatic polypeptide containing a repetitive Arg-Gly-Asp sequence. (1989) (8)
- Further purification of polysaccharides having anaphylactic activity from culture filtrate of human tubercle bacilli. (1967) (8)
- Regression of line-10 hepatocellular carcinomas following treatment with water-soluble, microbial extracts combined with trehalose or arabinose mycolates (1978) (8)
- Effect of MDP-Lys(L18), a derivative of MDP, on enhancing host resistance against Hantaan virus infection in newborn mice. (1995) (8)
- Activation of mouse peritoneal adherent cells with N-acyl muramyl dipeptide derivatives (1985) (8)
- Effect of cell-wall skeleton of Mycobacterium bovis BCG on cell-mediated cytotoxicity in tumor-bearing mice. (1975) (8)
- Effect of BCG cell-wall skeleton on metastasis of syngeneic tumor in rats, with special reference to lymphocyte trapping. (1978) (8)
- Serial passage of human immunodeficiency virus type 1 generates misalignment deletions in non-essential accessory genes. (1996) (8)
- Further studies on the structural requirements of agents for immunotherapy of the guinea pig line-10 tumor (1978) (8)
- Prophylactic activity of dihydro-heptaprenol, a synthetic polyprenol derivative, against Sendai virus infection in mice (1990) (7)
- Mannan decelerates the clearance of human red blood cells in SCID mouse. (1998) (7)
- Effect of systemic administration of mouse recombinant interferon-gamma on the lung tumor metastases in mice. (1989) (7)
- Isolation of tuberculin active peptides from cell wall fraction of human tubercle bacillus strain Aoyama B. (1969) (7)
- Activation by synthetic lipid A subunit analogues (GLA compounds) of tumoricidal properties in human blood monocytes. (1990) (7)
- Synthesis of N-acetyl-6-amino- and -6-(acylamino)-6-deoxymuramoyl dipeptides, and their immunoadjuvant activities. (1980) (7)
- Occurrence of 3-O-Methylmannose in the Polysaccharide of Leptospira biflexa Urawa (1976) (7)
- Synthesis and biological activity of some lipophilic derivatives of 1-thio-muramoyl-L-alanyl-D-isoglutamine. (1984) (7)
- Elevated gene expression of argininosuccinate synthetase in peripheral lymphocytes from systemic lupus erythematosus (SLE) patients. (1992) (7)
- Identification of 4‐O‐Methylmannose in Cell Wall Polysaccharide of Leptospira (1983) (7)
- Preparation of an adjuvant-active, tuberculin-free peptidoglycolipid from human tubercle bacilli. (1974) (7)
- Romurtide, a synthetic muramyl dipeptide derivative, accelerates peripheral platelet recovery in nonhuman primate chemotherapy model. (1996) (7)
- Protective effect of mucosal administration of recombinant human macrophage colony-stimulating factor (rhM-CSF) on mucosal infection of Sendai virus in mice. (1997) (7)
- Polymorphism in genes for the enzyme arginine deiminase among Mycoplasma species (1993) (7)
- Immunological Activity of Synthetic Cell-Wall Peptidoglycan Subunits (1976) (7)
- PHYSICOCHEMICAL, BIOCHEMICAL AND BIOLOGICAL PROPERTIES OF CHITIN DERIVATIVES (1984) (7)
- Purification and characterization of an immunologically active glycoprotein from Asperigillus fumigatus (1968) (7)
- A Facile Synthesis of N-Acetyl-muramyl-L-alanyl-D-isoglutamine and Its Carbohydrate Analogs, and Their Immunoadjuvant Activities (1978) (7)
- Synthesis and immunoadjuvant activity of N-[2-O-(2-acetamido- 1,2,3,5-tetradeoxy-1,5-imino-D-glucitol-3-yl)-D-lactoyl]- L-alanyl-D-isoglutamine. (1990) (7)
- Phagocytosis plays a dual role in activating dendritic cells; digestive production of active Toll-like receptor ligands and cooperation with Toll-like receptor signaling. (2010) (7)
- Synthesis of N-[2-S -(2-Acetamido-2,3-dideoxy-D-glucopyranose-3-y1)-2-Thio-D-Lactoyl]-L-alanyl-D-isoglutamine (1984) (6)
- Romurtide, a synthetic muramyl dipeptide derivative, promotes megakaryocytopoiesis through stimulation of cytokine production in nonhuman primates with myelosuppression. (1997) (6)
- The effect of ubiquinone-7 and its metabolites on the immune response. (1972) (6)
- Preferential adsorption of bovine fibrinogen dimer onto polymer microspheres having heterogeneous surfaces consisting of hydrophobic and hydrophilic parts (1992) (6)
- Adjuvant activities of synthetic lipid A subunit analogues and its conjugates with muramyl dipeptide derivatives. (1989) (6)
- Synthesis of immunologically active muramyl dipeptide derivatives containing a quinonyl moiety via aminoacyl intermediates. (1981) (6)
- Induction of resistance to tuberculosis in mice with defined components of Mycobacteria and with some unrelated materials. (1982) (6)
- Mitogenic Activity of Cell‐Wall Components in Mouse Spleen Cells (1977) (6)
- Suppression of Sendai virus growth by treatment with N alpha-acetylmuramyl-L-alanyl-D-isoglutaminyl-N epsilon-stearoyl-L-lysine in mice. (1987) (6)
- A lymphocyte blastogenesis inhibitory factor (LBIF) reversibly arrests a human melanoma cell line, A375, at G1 and G2 phases of cell cycle. (1990) (6)
- Synthesis of lipophilic muramyl dipeptide derivatives via O-aminoacyl intermediates. (1980) (6)
- Adjuvant activity of mycobacterial fractions. II. In vitro adjuvant activity of cell walls of mycobacteria, nocardia and corynebacteria. (1974) (6)
- Regression of line-10 hepatocellular carcinoma by a less toxic cord factor analogue combined with L18-MDP or synthetic lipid A analogues. (1988) (6)
- Synthesis and Structure-activity Relationship of N-(Acyl)muramoyl-dipeptides (1983) (6)
- Synthesis of (N-acetyl-1-O-acylmuramoyl)-L-alanyl-D-isoglutamines, and their immunoadjuvant activities. (1983) (6)
- Effect of Nocardia rubra cell-wall skeleton on the induction of lung cancer and amyloidosis by 3-methylcholanthrene in rabbits. (1980) (6)
- Inhibitory effect of Nocardia rubra cell wall skeleton on carcinogen-induced mammary tumorigenesis in rats. (1980) (6)
- Comparison of antimetastatic effect against Lewis lung carcinoma after intratumoral and intravenous injections of cell-wall skeleton of Propionibacterium acnes C7 in C57BL/6 mice. (1984) (6)
- Effect of Nocardia rubra cell-wall skeleton on the induction of lung cancer in ACI/N rats. (1979) (6)
- Chemical and Immunological Properties of Protein and Polysaccharide Fractions Extracted from Aspergillus fumigatus (1967) (5)
- Synthesis and immunoadjuvant activity of 2,2′-O-[2,2′-diacetamido-2,3,2′,3′-tetradeoxy-6,6′-di-O-(2-tetradecyl-hexadecanoyl)-α, α′-trahalose-3,3′-diyl]bis(N-d-lactoyl-l-alanyl-d-isoglutamine) (1989) (5)
- Effect of chitin heparinoids on the activation of peritoneal macrophages and on the production of monokines in mice. (1990) (5)
- Synthesis of N-[2-O-(2-acetamido-2,3-dideoxy-5-thio-d-glucopyranose-3-yl)-d-lactoyl]-l-alanyl-d-isoglutamine (1983) (5)
- Studies on the allergenicity of various tuberculoprotein derivatives and the adjuvanticity of wax D fractions of Mycobacterium tuberculosis. (1969) (5)
- Antimetastatic effect of cell-wall skeleton of Propionibacterium acnes C7 on Lewis lung carcinoma in C57BL/6J mice. (1981) (5)
- Enhancement by immunostimulants of the production by mouse spleen cells of factor(s) stimulating differentiation of mouse myeloid leukemic cells. (1981) (5)
- Immunologieal and Antitumor Activities of Synthetic 6-O-Mycoloyl-N-acetylmuramyldipeptides (1977) (5)
- Prophylactic effect of BCG cell-wall skeleton on the tumor induction by 7,12-dimethylbenz[a]anthracene in mice: strain difference. (1979) (5)
- Synthesis and immunoadjuvant activities of novel N-acylmuramoyl dipeptides related to the lipid A constituent of the bacterial lipopolysaccharide (1981) (5)
- Development of the cytokine inducer romurtide: experimental studies and clinical application. (1992) (5)
- Synthesis and biological properties of partially modified retro and retro-inverso pseudo peptides of arg-gly-asp (RGD) (1996) (5)
- Adjuvant Activity of Mycoloyl Derivatives of N‐Acetylmuramyl‐L‐alanyl‐D‐isoglutamine in Mice and Guinea Pigs (1979) (5)
- Synthesis and immunoadjuvant activity of acylamino analogs of N-acetylmuramoyl-L-alanyl-D-isoglutamine. (1982) (5)
- Enzymatic alcoholyses of NAD: A New type of ADP-ribosylation reaction catalysed by NAD glycohydrolase (1997) (5)
- The prevention of the orotic acid fatty liver by the administration of 5-aminoimidazolecarboxamide. (1962) (4)
- Combination of anti-cell adhesive synthetic Arg-Gly-Asp-Ser analogue and anticancer drug doxorubicin heightens their original antimetastatic activities. (1995) (4)
- Muroctasin, a muramyl dipeptide derivative. An introductory overview. (1988) (4)
- Further study on relationship of anti-tuberculous protection to lung granulomata produced by intravenous injections of synthetic 6-0-mycoloyl-N-acetyl-muramyl-L-alanyl-D-isoglutamine with or without specific antigens. (1982) (4)
- Innate immune therapy for cancer. Screen for molecules capable of activating the innate immune system. (2000) (4)
- Synthesis and immunoadjuvant activity of the conjugates of 1-thio-N-acetyl-muramoyl dipeptide with lipid A subunit analogs (1989) (4)
- Enzymic synthesis and characterization of some novel indazole nucleotides. (1983) (4)
- Inherited hyperactivation of L-arginine synthesis in gamma + B lymphocytes of systemic autoimmune MRL mice. (1990) (4)
- The effect of ubiquinone-7 and its metabolites on the immune response. III. The effect on the immune response to sheep erythrocytes and DNP-Lys-Ficoll in mice. (1976) (4)
- Effect of oil-attached BCG cell-wall skeleton on the induction of pleural fibrosarcomas in mice. (1976) (4)
- Immune response against cell-wall skeleton of Mycobacterium bovis BCG at the inoculation site and peripheral lymphoid organs. (2008) (4)
- The isolation and purification of polysaccharides from culture filtrate of human tubercle bacilli strain H37Rv. (1968) (4)
- Evidence for Enzymatic ADP-Ribosylation to Histidine and Related Dipeptides. (1994) (4)
- Synthesis and biological activity of O-(N-acetyl-β-muramoyl-l-alanyl-d-isoglutamine)-(1→6)-2-acylamino-2-deoxy-d-glucoses☆ (1982) (4)
- Triazolo[4,5‐b]‐ and Imidazo[4,5‐b]pyridines as Substrates of NAD Glycohydrolase: Evidence for Two Competitive Transglycosylatin Reaction Sites (2006) (4)
- Synthesis and immunoadjuvant activity of N-[2-O-(2-acetamido-2,3,di-deoxy-6-thio-D-glucopyranose-3-yl)-D-lac toy l]-L- alanyl-D-isoglutamine derivatives. (1984) (4)
- Bacillus Calmette‐Guérin cell‐wall skeleton enhances the killing activity of cytotoxic lymphocyte‐activated human dendritic cells transduced with the prostate‐specific antigen gene (2009) (4)
- Vaccination with B7-1+ Tumor and Anti-Adhesion Therapy with RGD Pseudo-Peptide (FC-336) Efficiently Induce Anti-Metastatic Effect (1998) (4)
- Differentiation and production of colony‐stimulating factor induced by immunostimulants in a leukemia cell line (1980) (4)
- Cubical anatomy of several ducts and vessels by injection method of acrylic resin. XI. Arterial distribution of the palatine tonsil in some mammals. (1961) (4)
- Effect of Nocardia rubra cell-wall skeleton treatment on tumor formation in two-stage chemical carcinogenesis of mouse skin (1981) (4)
- Adjuvant activity of bacterial glycolipids. (1976) (4)
- Synthesis and Biological Activities of 6-Amino- and 6-(Acylamino)-N-acetylmuramyl Dipeptides (1980) (3)
- Antimetastatic effect of endogenous tumor necrosis factor induced by the treatment of recombinant interferon γ followed by an analogue (GLA-60) to synthetic lipid A subunit (2005) (3)
- Terminal diols as efficient substrates for transglycosylational activity of NAD glycohydrolase. (1999) (3)
- Synthesis of Positional and Configurational Isomers of N-Acetylmuramyl-l-alanyl-d-isoglutamine (MDP), and Their Immunoadjuvant Activities (1980) (3)
- BCG-cell wall skeleton completely cures the immunologically eligible acute leukemia patients (1999) (3)
- Immunological activities of multiprenylacetyl derivatives of muramyldipeptides. (1988) (3)
- Prophylactic activity of dihydroheptaprenol, a synthetic polyprenol derivative, against Sendai virus infection in mice. (1990) (3)
- Effect of BCG cell-wall skeleton immunotherapy on the peripheral blood lymphocytes in patients with lung cancer after radiotherapy. (1978) (3)
- Experimental and clinical studies on the effects of synthetic muramyldipeptide derivatives on viral and opportunistic infections. (1986) (3)
- Staphylococcal enterotoxin A induced interferon (IFN)-gamma production in spleen cells from BCG-immunized mice: the IFN production is dependent on leukotriene C4 but not dependent on interleukin 2. (1990) (3)
- A new toxic glycolipid isolated from human tubercle bacillus. (1962) (3)
- Synthesis and Immunoadjuvant Activity of 1-α-O-, 1-β-S- and 6-O-(2-Tetra-decylhexadecanoyl) Derivatives of N-Acetylmuramoyl-L-alanyl-D-isoglutamine Methyl Ester (1991) (3)
- Prevention of cancer metastasis in mice with fibronectin-related substances. (1994) (3)
- Enzymatic Preparations and Regiochemical Properties of Some New ADP‐ Ribosylated 1,2,4‐Triazoles. (1991) (3)
- Synthesis of N-[2-O-(2-Acetamido-1,5-anhydro-2,3-dideoxy-D-glucitol-3-yl)-d-lactoyl]-l-alanyl-d-isoglutamine (1-Deoxy-MDP) and Some of Its Lipophilic Analogs, and Their Immunoadjuvant Activities (1986) (3)
- Preventive effect of a quinonyl derivative of N-acetylmuramyl dipeptide, QMDP-66, against adriamycin-induced ECG abnormalities in rats. (1983) (3)
- Macrophage activation and host augmentation against Sendai or herpes simplex virus (HSV) infections with synthetic polypeptides in mice. (1989) (3)
- Inhibition of pulmonary granuloma formation in mice by treatment with Mycobacterial protoplasm and immuno-suppressants and its relation to protection against aerosol infection with virulent Mycobacterium tuberculosis. (1981) (3)
- Combined treatment of syngeneic murine tumors and xenotransplanted human lung cancer by immunotherapy and radiotherapy. (1981) (3)
- Erythrocyte-replaced mouse model for Haemoparasite studies: comparison of NOD/shi-scid and C.B-17/Jcl-scid mouse upon acceptability of human erythrocytes. (2003) (3)
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- Regression of bovine lymphosarcoma by treatment with cell-wall skeleton of Nocardia rubra. (1989) (3)
- Regression of line-10 hepatocarcinoma with synthetic quinonyl muramyl dipeptide in strain-2 guinea pigs. (1983) (3)
- Effect of oil-attached BCG cell-wall skeleton and thymectomy on the incidence of lung cancer and amyloidosis induced by chemical carcinogens in rabbits. (1978) (3)
- Injection of cell-wall skeleton of Mycobacterium bovis BCG draining to a sentinel lymph node eliminates both lymph node metastases and the primary transplanted tumor. (2008) (3)
- Synthesis and Biological Activities ofN-Acetyl-6-O-acyl-1-thiomuramoyl-l-alanyl-d-isoglutamine Derivatives (1986) (3)
- MDP-Lys (L18), a Synthetic Muramyl Dipeptide Derivative, Enhances Antitumor Activity of an Inactivated Tumor Vaccine (2000) (3)
- The effect of ubiquinone-7 and its metabolites on the immune response. II. Adjuvant activity on the circulating antibody production and the effect on the liver lysosomal membrane. (1976) (2)
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- Inhibitory effect of chitin heparinoids on the lung metastasis of B16-B16 Melanoma (1991) (2)
- Chemical combination of 6-deoxy-6-mycoloylamino-α,α-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide (1989) (2)
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- SYNTHESIS OF 6-O-MYCOLOYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE WITH IMMUNOADJUVANT ACTIVITY (1977) (2)
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- Enzyme immunoassay of teichoic acids from Listeria monocytogenes (1985) (2)
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- In vitro activation of bovine macrophage and peripheral blood mononuclear cells by Nocardia rubra cell wall skeleton (N-CWS). (1990) (2)
- Therapeutic effect of cell-wall skeleton of Propionibacterium acnes in combination with a monoclonal antibody (C6-1.2) on the lung metastases of Lewis lung carcinoma. (1987) (2)
- Isolation and properties of mannans from Alternaria kikuchiana Tanaka and Alternaria zinniae. (1971) (2)
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- Synthesis and Biological Activity of 6–O-(3-Acyloxytetradecanoyl)-N-acetyl-muramoyl Dipeptide Methyl Esters and Related Compounds (1989) (2)
- Synthesis and Biological Activities of Lipophilic Derivatives of 1-Deoxy-N-acetylmuramoyl-l-alanyl-d-isoglutamine (1986) (1)
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- Stimulation of human immunodeficiency virus type 1 infected cells with superoxide enhances the chemotactic motile response of CD4+ human T cells: implication for virus transmission by cell-to-cell interaction. (1995) (1)
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- Synthesis and Biological Activity of the Lipophilic Derivatives of N-Acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine (1986) (1)
- Synthesis of N-{2-O-[2-Acetamido-1-O-acyl (or 1, 6-di-O-acyl)-2, 3-dideoxy-α-D-glucopyranose-3-yl]-D-lactoyl}-L-alanyl-D-isoglutamine Methyl Esters, and Their Immunoadjuvant Activities (1986) (1)
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- Chemical synthesis and adjuvant activity of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) analogs 1, 2. (1981) (1)
- Synthesis and Immunoadjuvant Activity of 1–S- and/or 6-O-(ω-Amino) Fatty Acylated Derivatives of N-Acetyl-1-thio-muramoyl-l-alanyl-d-isoglutamine Methyl Ester (1991) (1)
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- ENZYMIC SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL INDAZOLE NUCLEOTIDES (1983) (0)
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- SYNTHESIS OF IMMUNOLOGICALLY ACTIVE MURAMYL DIPEPTIDE DERIVATIVES CONTAINING A QUINONYL MOIETY VIA AMINOACYL INTERMEDIATES (1982) (0)
- Effect of dihydroheptaprenol on nonspecific resistance to bacterial infections in immunocompromised mice (1988) (0)
- Th17 (PP-014) (2010) (0)
- Optimization of Microwave-assisted Extraction of Polysaccharides from the Fruiting Body of Mushrooms (2006) (0)
- Monoclonal antibodies to Lewis lung carcinoma (2004) (0)
- [Basic studies on tuberculosis and tubercle bacilli in U.S.-Japan medical cooperative program tuberculosis panel]. (1996) (0)
- [Immunochemistry of tubercle bacilli, with special reference to adjuvant activity (author's transl)]. (1981) (0)
- Synthesis of Novel Mycoloyl Derivatives of l-Glucose, 2-Deoxy-d-glucose, d-Glucosamine, and 1,5-Anhydro-d-glucosaminitol (1989) (0)
- SYNTHESIS AND THE ADJUVANT AND TUMOR-SUPPRESSIVE ACTIVITIES OF QUINONYL MURAMYL DIPEPTIDES (1985) (0)
- Immunology; drug resistance; gene amplification (2004) (0)
- Effect of Nocardia rubra cell wall skeleton and/or cyclophosphamide on leukemogenesis induced by N-ethyl-N-nitrosourea in Donryu rats (2004) (0)
- Immunomodulatory and therapeutic properties of ubenimex (bestatin) (1991) (0)
- [Pathology of epithelioid cell granulomas in relation to the cell components of Mycobacterium tuberculosis]. (1979) (0)
- Studies on the Toxic Substances Isolated from Mycobacteria1 (2015) (0)
- Synthesis and immunoadjuvant activity of 2,2'-O-[2,2'-diacetamido-2,3,2',3'-tetradeoxy-6,6'-di-O-(2-tetradecyl- hexadecanoyl)-alpha,alpha'-trehalose-3,3'-diyl]bis(N-D-lactoyl-L-alanyl -D-isoglutamine). (1989) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS, PART XXIII. SYNTHESIS OF N-(2-O-(2-ACETAMIDO-2,3-DIDEOXY-5-THIO-D-GLUCOPYRANOSE-3-YL)-D-LACTOYL)-L-ALANYL-D-ISOGLUTAMINE (1984) (0)
- SYNTHESIS OF LIPOPHILIC MURAMYL DIPEPTIDE DERIVATIVES VIA O-AMINOACYL INTERMEDIATES (1981) (0)
- [Radiographic diagnosis of bladder neoplasms]. (1976) (0)
- Workshop 12Antimetastatic effect by systemic administration of mouse recombinant IFN-γ against pulmonary metastases in mice (1988) (0)
- 2.Purification and Properties of Fungal Polysaccharides(Candida Allergy) (1972) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS, PART XXV. SYNTHESIS AND BIOLOGICAL ACTIVITIES OF N-ACETYL-1-THIOMURAMOYL-L-ALANYL-D-ISOGLUTAMINE AND SOME OF IT LIPOPHILIC DERIVATIVES (1984) (0)
- Stimulation with Synthetic Acyl-MDP Derivatives of Host-Defense Mechanism against Cancer and Viral Infections (1986) (0)
- [Chemical synthesis and immunologic activities of the active unit of BCG-CWS]. (1981) (0)
- [Symposium B. I. Studies on the antigen in the skin reaction]. (1969) (0)
- Effect of the Substituent Groups of SCM-Chitin-RGDS Conjugate on Inhibitory Activity of Tumor Metastasis (1995) (0)
- [Antitumor activity and action mechanisms of BCG cell-wall skeleton and related substances]. (1977) (0)
- [Adjuvant effect of various wax D fractions during development of tuberculin allergy reaction]. (1970) (0)
- Major polypeptide with repeated sequences that are set in the cell. (1989) (0)
- Histological study of local skin injected with adjuvant-active and -inactive muramyl dipeptide (MDP) (histological change in MDP injected skin. (1983) (0)
- [Chemistry, biology, and pathology of Mycobacteria grown in vivo. 3. Biochemical study of the cellular components of M. lepraemurium Hawaii grown in vivo and in vitro]. (1976) (0)
- Antitumor activity with cell wall skeleton of BCG in rat syngeneic tumor. (1979) (0)
- Effect of Muramyl Dipeptide on Phagocyte Functions in Rainbow Trout (Oncorhynchus mykiss) (1993) (0)
- muramyl dipeptides derivatives (1983) (0)
- Characterization of human neuroblastoma-derived thymic cell growth factor (NTGF) (1988) (0)
- Enzymatic ADP-Ribosylation of Benzotriazoles and Related Triazoles. Difference of Glycosidation Site Between Triazoles and Indazoles. (1989) (0)
- Monoclonal antibodies distinguish between the head portions of two myosin isozymes from chicken breast muscle. (1986) (0)
- [Chemistry and biological activities of the components of Mycobacterium tuberculosis]. (1975) (0)
- [New technology of vaccine production--international prospect of the development. Development of synthetic immunologic adjuvants and MDP-antigen binding vaccines]. (1987) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS. PART XV. SYNTHESIS AND IMMUNOADJUVANT ACTIVITIES OF THE REPEATING, DISACCHARIDE-DIPEPTIDE UNIT OF THE BACTERIAL, CELL-WALL PEPTIDOGLYCAN AND OF SOME CARBOHYDRATE ANALOGS (1982) (0)
- A curable resin composition, its use in a paint composition and method for producing a top coat (1994) (0)
- Synthesis and Immunoadjuvant Activity of 2,2′-O-(2,2′-Diacetamido-2,3,2′,3′-tetradeoxy-6,6′-di-O-(2-tetradecylhexadecanoyl)-α,α′-trehalose-3,3′-diyl)bis(N-D-lactoyl-L-alanyl-D-isoglutamin# e). (1990) (0)
- [Symposium: microstructure, composition and immunology of Mycobacterium tuberculosis]. (1970) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS, PART XXII. CHEMICAL MODIFICATION OF THE C-6 SUBSTITUENT IN THE CARBOHYDRATE MOIETY OF N-ACETYLMURAMOYL-L-ALANYL-D-ISOGLUTAMINE (MDP), AND THE IMMUNOADJUVANT ACTIVITY (1984) (0)
- Syntheses of Trehalose Monomycolate and Related Compounds, and Their Lethal Toxicity and Adjuvant Activity. (1986) (0)
- Protective Activity of MDP-Lys (L-18) and Recombinant Cytokines Against Sendai Virus and Herpes Simplex Virus (HSV) Infections in Mice (1990) (0)
- Fruiting bodies of Basidiomycetes mushrooms have been attracted increasing attention of pharmaceutical and functional food industry because of their health promotion and disease alleviation effects on human health. On ac- count of bioactive and medicinal activities, immune- (2009) (0)
- Adjuvant and mitogenic activities of niacine derivatives and their NAD-analogs. (1981) (0)
- Contents, Vol. 43, 1972 (1972) (0)
- Cancer Immunotherapy in Japan (1984) (0)
- Chemical combination of 6-deoxy-6-mycoloylamino-alpha,alpha-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide. (1989) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS, PART 28. SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME LIPOPHILIC DERIVATIVES OF 1-THIOMURAMOYL-L-ALANYL-D-ISOGLUTAMINE (1985) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS, PART 27. SYNTHESIS AND IMMUNOADJUVANT ACTIVITY OF N-(2-O-(2-ACETAMIDO-2,3-DI-DEOXY-6-THIO-D-GLUCOPYRANOSE-3-YL)-D-LACTOYL)-L-ALANYL-D-ISOGLUTAMINE (1984) (0)
- Nonspecific Adjuvant Immunotherapy of Lung Cancer with Cell Wall Skeleton of Mycobacterium bovis Bacillus e-1 (2004) (0)
- Nouvelle methode d'induction de lymphocytes t specifiques d'un antigene (2002) (0)
- Resin composition having a high solids content and paints with high solids content (1993) (0)
- Human lymphocyte blastogenesis inhibitory factor (LBIF) II. Distinction from other cell growth inhibitors (1988) (0)
- Enzymic Synthesis und Biochemical Activity of Various Indazole Adenine Dinucleotides. (1985) (0)
- Cancer metastasis-inhibiting agent using carboxymethylated chitin derivative (1992) (0)
- Enhancement of host resistance against sendai virus infection by chemically defined adjuvants or recombinant cytokines in mice (1988) (0)
- Effective Synthesis of Four Isomeric Trehalose Dicorynomycolates ( TDCMs) and Their Immunoadjuvant Activities. (1996) (0)
- [BCG vaccine in cancer immunotherapy]. (1980) (0)
- Synthesis and Immunoadjuvant Activity of NAcetyl–6-O-phosphono-muramoyl-l-alanyl-d-isoglutamine Methyl Ester and Its Lipophilic Derivatives (1989) (0)
- Synthesis and Biological Activities of N-Acetyl-6-O-acyl-1-S-acyl-1- thiomuramoyl-L-alanyl-D-isoglutamine Derivatives. (1987) (0)
- [Chemial structure of cell walls prepared from nocardia, corynebacteria and mycobacteria]. (1970) (0)
- Behcet's disease and streptococci — The role of S.Salivarius the mechanism of aphthous ulceration (1990) (0)
- [RECENT PROGRESS IN BIOSYNTHESIS OF FATTY ACIDS]. (1964) (0)
- STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS. PART 26. SYNTHESIS OF N-(2-S-(2-ACETAMIDO-2,3-DIDEOXY-D-GLUCOPYRANOSE-3-YL)-2-THIO-D-LACTOYL)-L-ALANYL-D-ISOGLUTAMINE (1984) (0)
- 18 Systematic Synthesis of Trehalose Dicorynomycolate (TDCM) Analogues and Their IL-6 Level Enhancement Activity (2006) (0)
- Adjuvanticity of mycobacterial cell walls(Notes) (1971) (0)
- Isolation and Characterization of Arabinose Mycolate from Firmly Bound Lipids of Mycobacteria 1 (0)
- Bovine lactoferirn and lactoferrcinTM inhibit tumor metastasis in mice. (1998) (0)
- Anti Tumor Effects and Cell Cycle Analysis of Δ^12-Prostaglandin J_2 (1987) (0)
- Synthesis and Immunoadjuvant Activity of the Phosphorylated Derivatives of 1-β-S-Acyl- and 6-O-Acyl-1-deoxy-N-acetylmuramoyl-l-alanyl-d-isoglutamine Methyl Esters (1991) (0)
- Peptide derivatives and their use (1992) (0)
- Synthesis and Immunoadjuvant Activity of 1-α-O- and 1-β-S-[(3R)-3-Tetradecanoyloxy-tetradecanoyl]-N-acetylmuramoyl-L-alanyl-D-isoglutamine Methyl Esters and Related Compounds (1993) (0)
- Synthetic Immunomodifiers (I) (1989) (0)
- Suppressive effect of indazole adenine dinucleotides on proliferation of normal and malignant cells. (1986) (0)
- Acnes c7 in mice and guinea pigs. (1979) (0)
- [Diagnosis by x-ray television]. (1969) (0)
- [Treatment of dysfunction of cellular immunity and the prospect for future]. (1978) (0)
- [Radiotherapy of bladder neoplasms]. (1977) (0)
- Curable resin composition, their use and Paints (1994) (0)
- Enhancement of macrophage cytotoxicity to tumors and production of megakaryocyte-stimulating factors by microbial agents. (1980) (0)
- [25 years progress in tubercule bacillus research--report of tuberculosis panels in silver jubilee of the Japan-U.S. Cooperative Medical Science Program]. (1991) (0)
- Endotoxin antagonism by a synthetic lipid A analogue, DT-5461, with low endotoxicity in human peripheral blood monocytes. (1995) (0)
- Macrophage activation with pantethine and pantetheine-4'-phosphate. (1985) (0)
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What Schools Are Affiliated With Ichiro Azuma?
Ichiro Azuma is affiliated with the following schools:
