Isidore S. Edelman
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Philosophy Biology
Isidore S. Edelman's Degrees
- PhD Molecular Biology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Isidore S. Edelman Influential?
(Suggest an Edit or Addition)Isidore S. Edelman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). (1996) (1526)
- The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene (1993) (1270)
- Interrelations between serum sodium concentration, serum osmolarity and total exchangeable sodium, total exchangeable potassium and total body water. (1958) (484)
- Anatomy of body water and electrolytes. (1959) (441)
- The measurement of total body water in the human subject by deuterium oxide dilution; with a consideration of the dynamics of deuterium distribution. (1950) (371)
- Self-diffusion and Structure of Liquid Water. III. Measurement of the Self-diffusion of Liquid Water with H2, H3 and O18 as Tracers1 (1953) (351)
- The Mechanism of the Calorigenic Action of Thyroid Hormone (1971) (342)
- Subcellular mechanisms in the action of adrenal steroids. (1972) (240)
- Mechanism of thyroid calorigenesis: role of active sodium transport. (1970) (234)
- The roles of plasma binding and receptor specificity in the mineralocorticoid action of aldosterone. (1973) (228)
- Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia. (2001) (211)
- ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF RNA SYNTHESIS. (1963) (208)
- Calcium dependence of glucocorticoid-induced lymphocytolysis. (1977) (178)
- Mechanism of action of steroid hormones. (1975) (176)
- Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder (1983) (167)
- Glucocorticoid receptors in rat kidney: the binding of tritiated-dexamethasone. (1973) (166)
- Thyroid thermogenesis. Relationships between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in rat skeletal muscle. (1976) (153)
- Effect of triiodothyronine on the synthesis and degradation of renal cortical (Na+ + k+)-adenosine triphosphatase. (1976) (152)
- Electrolyte composition of bone and the penetration of radiosodium and deuterium oxide into dog and human bone. (1954) (142)
- THE ACTION OF ALDOSTERONE AND RELATED CORTICOSTEROIDS ON SODIUM TRANSPORT ACROSS THE TOAD BLADDER. (1964) (141)
- Glucocorticoid and mineralocorticoid receptors for aldosterone. (1972) (140)
- Body Composition: Studies in the Human Being by the Dilution Principle. (1952) (140)
- Dependence of renal (Na+ + k+)-adenosine triphosphatase activity on thyroid status. (1976) (140)
- CALCIUM INHIBITION OF THE ACTION OF VASOPRESSIN ON THE URINARY BLADDER OF THE TOAD. (1964) (135)
- ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF PROTEIN SYNTHESIS. (1963) (129)
- Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia. (1997) (127)
- Evidence for a new class of corticosterone receptors in the rat kidney. (1973) (120)
- Effects of Ca++ and prostaglandin E1 on vasopressin activation of renal adenyl cyclase. (1971) (115)
- Studies on renal aldosterone-binding proteins. (1968) (113)
- Specific aldosterone binding in rat kidney and parotid. (1972) (113)
- Body sodium and potassium. III. Interrelated trends in alimentary, renal and cardiovascular disease; lack of correlation between body stores and plasma concentration. (1954) (111)
- On the biochemical mechanism of action of aldosterone. (1968) (111)
- Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304). (1974) (110)
- Induction of RNA and protein synthesis in the action of aldosterone in the rat. (1967) (109)
- The volume of distribution of sodium thiosulfate as a measure of the extracellular fluid space. (1952) (108)
- Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors. (1974) (102)
- Relationships between renal cytoplasmic and nuclear aldosterone-receptors. (1972) (102)
- Total exchangeable sodium, total exchangeable potassium, and total body water in edematous patients with cirrhosis of the liver and congestive heart failure. (1958) (99)
- Stereospecific binding of aldosterone to renal chromatin. (1970) (97)
- Thyroid thermogenesis and active sodium transport. (1974) (91)
- Further observations on total body water. I. Normal values throughout the life span. (1952) (89)
- Effects of thyroid status on electrolyte distribution in rat tissues. (1973) (84)
- Thyroid hormone control of Na+-K+-ATPase and K+-dependent phosphatase in rat heart. (1977) (82)
- Characteristics of the renal nuclear receptors for aldosterone. (1966) (79)
- Thyroidal regulation of rat renal and hepatic Na,K-ATPase gene expression. (1988) (73)
- Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro (1979) (73)
- 31P NMR studies of intact anchorage-dependent mouse embryo fibroblasts. (1981) (72)
- Effects of aldosterone and vasopressin on electrolytes of toad bladder epithelial cells. (1971) (71)
- Body sodium and potassium. IV. The normal total exchangeable sodium; its measurement and magnitude. (1954) (69)
- Exchange of water between blood and tissues; characteristics of deuterium oxidases equilibration in body water. (1952) (68)
- Metabolic Changes Associated with Mitral Valvuloplasty (1954) (68)
- Effect of Thyroid Hormone on the Abundance of Na, K-Adenosine Triphosphatase α-Subunit Messenger Ribonucleic Acid* (1987) (67)
- The role of the tricarboxylic acid cycle in the action of aldosterone on sodium transport (1967) (67)
- The measurement of deuterium oxide in body fluids by the falling drop method. (1951) (64)
- Stereospecific nuclear and cytosol aldosterone-binding proteins of various tissues. (1969) (63)
- Assembly of the (Na+ + K+)-adenosine triphosphatase. Post-translational membrane integration of the alpha subunit. (1984) (62)
- Aldosterone stimulation of sodium transport (1967) (62)
- 10 – Regulation of Thermogenesis by Thyroid Hormones (1983) (61)
- Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis. (1978) (60)
- Gastrointestinal water and electroyltes. IV. The equilibration of deuterium oxide (D2O) in gastrointestinal contents and the proportion of total body water (T.B.W.) in the gastrointestinal tract. (1957) (57)
- KINETIC ANALYSIS OF THE ANTIDIURETIC ACTION OF VASOPRESSIN AND ADENOSINE-3',5'-MONOPHOSPHATE. (1964) (56)
- Critical role played by thyroid hormone in induction of neoplastic transformation by chemical carcinogens in tissue culture. (1983) (56)
- CHEMICAL CONCENTRATION GRADIENTS AND ELECTRICAL PROPERTIES OF GASTRIC MUCOSA. (1964) (53)
- CONTROL OF APICAL SODIUM PERMEABILITY IN THE TOAD URINARY BLADDER BY ALDOSTERONE (1981) (52)
- Current-voltage analysis of apical sodium transport in toad urinary bladder: Effects of inhibitors of transport and metabolism (1980) (51)
- Aldosterone control of the density of sodium channels in the toad urinary bladder (2005) (51)
- Stimulation of Na,K-activated adenosine triphosphatase and active transport by low external K+ in a rat liver cell line (1986) (49)
- The role of sodium-channel density in the natriferic response of the toad urinary bladder to an antidiuretic hormone (2005) (49)
- The equilibration of radiosodium (Na24), radiopotassium (K42), and deuterium oxide (D2O) in hydropic human subjects. (1957) (48)
- Further studies on the effect of aldosterone on electrical resistance of toad bladder. (1975) (46)
- Increased abundance of Na+-K+-ATPase mRNAs in response to low external K+. (1988) (46)
- The use of the mass spectrometer to measure deuterium in body fluids. (1950) (45)
- Binding of aldosterone to cytoplasmic and nuclear receptors of the urinary bladder epithelium of Bufo marinus. (1978) (44)
- Receptors and effectors in hormone action on the kidney. (1981) (42)
- Further observations on total body water. II. Changes of body composition in disease. (1952) (41)
- Time-Course of the Effects of Thyroid Hormone on Respiration and Na+ + K+-ATPase Activity in Rat Liver 1 (1974) (41)
- The Coupling of the Short-Circuit Current to Metabolism in the Urinary Bladder of the Toad (1963) (40)
- Studies on the influence of the low sodium cardiac diet and the Kempner regimen on renal hemodynamics and electrolyte excretion in hypertensive subjects. (1950) (40)
- Dihydrocortisol: a potential mineralocorticoid. (1978) (40)
- Autoradiographic localization of corticosterone receptors (type III) to the collecting tubule of the rat kidney. (1975) (39)
- Effect of actinomycin D on aldosterone-mediated changes in electrolyte excretion. (1973) (39)
- Kinetics of RNA labeling in toad bladder epithelium: effects of aldosterone and related steroids. (1974) (39)
- Electrolyte and lipid composition of skeletal and cardiac muscle in mice with hereditary muscular dystrophy. (1959) (39)
- Isolation of rat kidney cortical tubules enriched in proximal and distal segments. (1979) (36)
- Auto‐Anti‐Idiotype: A Basis for Autoimmunity and a Strategy for Anti‐Receptor Antibodies (1986) (36)
- Interrelations of plasma potassium concentration, plasma sodium concentration, arterial pH and total exchangeable potassium. (1959) (36)
- Internal image properties of a monoclonal auto-anti-idiotypic antibody and its binding to aldosterone receptors. (1989) (34)
- Relationship between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in the action of thyroid hormone on rat jejunal mucosa. (1979) (33)
- The action of aldosterone on sodium transport: further studies with inhibitors of RNA and protein synthesis. (1973) (32)
- Mediating events in the action of aldosterone. (1980) (32)
- Studies on VEM and VDM in blood in relation to renal hemodynamics and renal oxygen extraction in chronic congestive heart failure. (1950) (31)
- Crucial role of thyroid hormone in x-ray-induced neoplastic transformation in cell culture. (1981) (31)
- Hydrogen-ion dependence of the antidiuretic action of vasopressin, oxytocin and deaminooxytocin. (1965) (31)
- Characteristics of thyroid-stimulated Na+-K+-ATPase of rat heart. (1977) (31)
- The pathogenesis of hyponatremia: physiologic and therapeutic implications. (1956) (30)
- Transport through biological membranes. (1961) (29)
- Glucocorticoid stimulation of Na-K-ATPase in superfused distal segments of kidney tubules in vitro. (1982) (29)
- Body sodium and potassium. I. Simultaneous measurement of exchangeable sodium and potassium in man by isotope dilution. (1954) (29)
- Generation of an auto-anti-idiotypic antibody that binds to glucocorticoid receptor. (1986) (29)
- Thyroid thermogenesis. (1974) (28)
- High-resolution YAC-cosmid-STS map of human chromosome 13. (1998) (26)
- Rat liver adenyl cyclase activity in various thyroid states. (1972) (26)
- Thyroidal regulation of renal energy metabolism and (Na+ + K+)-activated adenosine triphosphatase activity. (1975) (26)
- Gastrointestinal water and electrolytes. I. The equilibration of radiosodium in gastrointestinal contents and the proportion of exchangeable sodium (Nae) in the gastrointestinal tract. (1956) (26)
- Aldosterone receptor occupancy and sodium transport in the urinary bladder of Bufo marinus. (1978) (26)
- On the mechanism of action of aldosterone on sodium transport: effects of inhibitors of RNA and of protein synthesis. (1966) (25)
- Steroidal 21-diazo ketones: photogenerated corticosteroid receptor labels. (1975) (24)
- The initiation mechanism in the action of aldosterone on sodium transport. (1972) (23)
- Hormonal regulation of Na,K-ATPase. (1988) (22)
- Transport of potassium by the gastric mucosa of the frog. (1960) (22)
- Effects of corticosteroids on electrolyte metablism during osmoregulation in teleosts. (1960) (22)
- Na(+)-K(+)-ATPase in adipocyte differentiation in culture. (1990) (22)
- Glucocorticoid receptors in rat kidney cortical tubules enriched in proximal and distal segments. (1981) (22)
- Calcium dependence of ionophore A23187-induced lymphocyte cytotoxicity. (1978) (22)
- Kinetic analysis of Na,K-activated adenosine triphosphatase induced by low external K+ in a rat liver cell line. (1988) (21)
- The role of sodium transport in thyroid thermogenesis. (1979) (19)
- Effect of pH and theophylline on uptake, elution, and antidiuretic action of cyclic AMP. (1967) (19)
- Photoaffinity site-specific covalent labeling of human corticosteroid-binding globulin. (1976) (19)
- Actions of aldosterone on polyadenylated ribonucleic acid and Na+ transport in the toad bladder. (1976) (17)
- Paraplegia secondary to metastatic prostatic carcinoma treated with stilbestrol; report of a case. (1949) (17)
- Metabolic regulation of apical sodium permeability in toad urinary bladder in the presence and absence of aldosterone (2005) (16)
- Loss of thyroidal inducibility of Na,K-ATPase with neoplastic transformation in tissue culture. (1986) (16)
- Effect of potassium on ion transport and bioelectric potentials of frog gastric mucosa. (1958) (16)
- Stimulation of Na+ transport across the toad urinary bladder by p-chloromercuribenzene sulfonate. (1976) (16)
- Effect of aldosterone on abundance and phosphorylation kinetics of Na-K-ATPase of toad urinary bladder. (1984) (15)
- Dual action of aldosterone on toad bladder: Na+ permeability and Na+ pump modulation. (1984) (15)
- Induction of citrate synthase by aldosterone in the rat kidney (1978) (14)
- Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions. (2000) (14)
- CHAPTER 8 – Mineralocorticoids (1970) (14)
- Nuclear binding of T3 and effects of QO2, Na-K-ATPase, and alpha-GPDH in liver and kidney. (1981) (14)
- Anomalous mobilities of Na,K-ATPase alpha subunit isoforms in SDS-PAGE: identification by N-terminal sequencing. (1991) (14)
- A high-resolution annotated physical map of the human chromosome 13q12-13 region containing the breast cancer susceptibility locus BRCA2. (1996) (14)
- Isoforms of Na,K-ATPase inArtemia salina: II. Tissue distribution and kinetic characterization (1989) (13)
- Low-angle neutron scattering analysis of Na/K-ATPase in detergent solution. (1987) (13)
- Studies on Thiomerin—A Subcutaneously Administerable Mercurial Diuretic (1950) (13)
- Tritium Assay by Liquid Scintillation Spectrometry: Comparison of Tritium and Deuterium Oxides as Tracers for Body Water (1960) (13)
- Modulation of adenovirus transformation by thyroid hormone. (1983) (13)
- Actions of aldosterone on rRNA and Na+ transport in the toad bladder. (1976) (13)
- Assembly of ordered contigs of cosmids selected with YACs of human chromosome 13. (1994) (12)
- SPECIFIC ACTION OF ALDOSTERONE ON RNA SYNTHESIS. (1964) (12)
- Effects of sulfhydryl reagents on basal and vasopressin-stimulated Na+ transport in the toad bladder. (1975) (12)
- Occupancy of aldosterone binding sites in rat kidney cytosol (1978) (12)
- The response of an established line of rat liver cells to thyroid hormone. (1986) (12)
- Transition from the polikilotherm to the homeotherm: possible role of sodium transport and thyroid hormone. (1976) (11)
- Reduced ouabain inhibition of Na,K-activated adenosine triphosphatase in cultured cell recipients of the ouabain-resistance gene. (1986) (11)
- The role of sodium, potassium and water in the hypo-osmotic states of heart failure. (1961) (11)
- Spironolactone antagonism of aldosterone action on Na+ transport and RNA metabolism in toad bladder epithelium (1977) (10)
- Effect of thyroid hormone on the abundance of Na,K-adenosine triphosphatase alpha-subunit messenger ribonucleic acid. (1987) (9)
- Cordycepin and α-amanitin: Inhibitors of transcription as probes of aldosterone action (1972) (9)
- Serum independence of low K+ induction of Na,K-ATPase: Possible role of c-fos (2004) (9)
- The membrane surfaces of the toad bladder: Scanning and transmission electron-microscopy (2005) (9)
- Relationship between potassium, acid secretion and bioelectric potentials of frog gastric mucosa in the presence of histamine and thiocyanate. (1959) (9)
- Distribution of aldosterone receptors in rat kidney cortical tubules enriched in proximal and distal segments. (1979) (9)
- Subcellular Distribution and Mode of Action of Aldosterone (1966) (8)
- Effect of high extracellular K+ on Na-K-ATPase in cultured canine kidney cells. (1990) (8)
- Effects of aldosterone on Na+ transport in the toad bladder. I. Glycolysis and lactate production under aerobic conditions. (1976) (8)
- Physiological and morphological effects of poly-L-lysine on the toad bladder (1969) (8)
- Gastrointestinal water and electrolytes. II. The equilibration of radiopotassium in gastrointestinal contents and the proportion of exchangeable potassium (Ke) in the gastrointestinal tract. (1956) (7)
- Isolation of radio-iodinated apical and basal-lateral plasma membranes of toad bladder epithelium (1979) (7)
- Intracellular Action of Aldosterone on Sodium Transport (1969) (7)
- Characteristics of antibodies to guinea pig (Na++K+)-adenosine triphosphatase and their use in cell-free synthesis studies (2005) (6)
- Cell-free transcription and translation of Na,K-ATPase alpha and beta subunit cDNAs. (1990) (6)
- Renal Aldosterone Receptors : Studies with [ 3 H ] Aldosterone and the Anti-Mineralocorticoid [ 3 H ] Spirolactone ( SC-26304 ) ( kidney / aldosterone receptors / tritiated spirolactone ) (6)
- Iodination (125I) of the apical plasma membrane of toad bladder epithelium: Electron-microscopic autoradiography and physiological effects (1973) (6)
- Effects of 3'-deoxycytidine on rRNA synthesis in toad bladder: analysis of response to aldosterone. (1977) (6)
- Effects of aldosterone on Na+ transport in the toad bladder. II. The anaerobic response. (1976) (5)
- A technique for differential extraction of nuclear receptors. (1975) (5)
- Aldosterone Binding Proteins (1971) (5)
- Effects of Thyroid Hormone on Adenine Nucleotide Content of Rat Liver 1 (1973) (5)
- Isolation of two isoforms of Na,K-ATPase from Artemia salina: kinetic characterization. (1988) (5)
- Thyroid thermogenesis: Minimal contribution of energy requirement for protein synthesis (1976) (5)
- Potassium and the transmucosal resistance of the frog gastric mucosa. (1960) (5)
- Effect of aldosterone on incorporation of amino acids into renal medullary proteins (1978) (4)
- Differential covalent labeling of apical and basal-lateral membranes of the epithelium of the toad bladder (1976) (4)
- THE ROLE OF EXTRARENAL TRANSPORT MECHANISMS IN THE REGULATION OF BODY POTASSIUM CONTENT (1963) (4)
- THE AUTO-ANTI-IDIOTYPIC ROUTE TO ANTI-RECEPTOR ANTIBODIES1 (1986) (4)
- Formation of Oriented Membrane Multilayers of Na/K‐ATPase a (1984) (4)
- Mg-Dependent, Zn-ATPase: Enzymatic Characteristics, Ion Specificities and Tissue Distribution (2001) (4)
- Biochemistry of the Action of Aldosterone on Sodium Transport (1967) (4)
- Mechanism of action of aldosterone: energetic and permeability factors. (1979) (3)
- Gastrointestinal water and electroyltes. III. The equilibration of radiobromide in gastrointestinal contents and the proportion of exchangeable chloride (Cle) in the gastrointestinal tract. (1957) (3)
- Identification of an epitope shared by the DNA-binding domain of glucocorticoid receptor and the B chain of insulin. (1989) (3)
- Cordycepin and alpha-amanitin: inhibitors of transcription as probes of aldosterone action. (1972) (3)
- Isoforms of Na,K-ATPase inArtemia saline: I. Detection by FITC binding and time course (1989) (3)
- Hormonal regulation of Na+ channels in tight epithelia. (1985) (3)
- Recent progress in the study of potassium metabolism. (1955) (3)
- Thyroid and Sodium Transport (1973) (2)
- Sodium thiosulfate dilution as a measure of the volume of fluid outside of body cells. (1951) (2)
- On the mechanism of action of aldosterone on sodium transport: the role of protein synthesis. 1963. (1999) (2)
- Method for simultaneous measurement of total exchangeable body sodium and potassium in man (1953) (1)
- Radio-iodination of plasma membranes of toad bladder epithelium (1979) (1)
- The turnover rate of body water in the human. (1951) (1)
- Effect of thyroid hormones on biochemical processes. (1979) (1)
- 233. Effects of aldosterone on nuclear and cytoplasmic RNA of toad bladder epithelium (1974) (1)
- Tissue-specific differences in the expression of the genes encoding the alpha and beta subunits of rat Na,K-ATPase. (1988) (1)
- The mechanism of the respiratory and transport effect of thyroid hormone on small intestinal mucosa. (1978) (1)
- The mechanism of action of spirolactones. (1975) (1)
- P NMR studies of intact anchorage-dependent mouse embryo fibroblasts ( cell culture / intracellular pH / intracellular ATP / 2-deoxyglucose ) (1)
- Sodium content of gastrointestinal secretions and the penetration of radiosodium into the gastrointestinal tract (1954) (1)
- Role of energy metabolism in the action of aldosterone on Na+ transport. (1965) (0)
- Thyroid hormone regulation of myocardial Na,K-ATPase (1987) (0)
- Effects of aldosterone and vasopressin on adenyl cyclase activity of rat kidney. (1972) (0)
- Basic Principles of Transport Across Cell Membranes. (1962) (0)
- TRANSPORT: THE ROLE OF RNA SYNTHESIS* (2016) (0)
- MECHANISM OF ACTION OF STEROID HORMONES (1976) (0)
- Hormones and the single cell: a relationship prerequisite for transformation. (1982) (0)
- Potassium content of gastrointestinal secretions and its relation to total exchangeable potassium (1955) (0)
- Renal aldosterone-binding proteins. (1968) (0)
- Equilibration of water and sodium in blood and tissues (2005) (0)
- AN OFFICIAL JOURNAL oftk AMERICAN HEART ASSOCIATION (1960) (0)
- Modulation of adenovirus transformation by thyroid hormone (triiodothyronine/tumor promoter/CREF cells/temperature-sensitive mutant/viral transformation) (2016) (0)
- Antibodies to Acetylcholine, Adenosine and Glucocorticoid Receptors by an Auto-Anti-Idiotypic Route (1987) (0)
- Antibodies to Na,K-ATPase: Characterization and Use in Cell-Free Synthesis Studies (1983) (0)
- The effect of thyroid disease on water turnover rate in the human subject. (1953) (0)
- Aldosterone, genes, and salt metabolism. (1965) (0)
- Annual Review of Physiology, Vol. 44 (1982) (0)
- Research vs. social medicine? Demands of society upon medical research. (1970) (0)
- Dependence of lonophore A23187-induced Lymphocyte Cytotoxicity1 (2006) (0)
- Tribute to Gordon Tomkins (1976) (0)
- Cell-free Transcription and Translation of Na,K-ATPase a! and @ Subunit cDNAs* (2001) (0)
- Gordon M. Tomkins - a dedication. (1979) (0)
- 2 METABOLIC CHANGES IN MITRAL VALVULOPLASTY CHANGES IN LATE CONVALESCENCE (0)
- EQUILIBRATION OF RADIOBROMIDE IN GASTROINTESTI- NAL CONTENTS AND THE PROPORTION OF EX- (0)
- Effect of aldosterone on protein synthesis in rat kidney slices (1975) (0)
- Acceptance of the 1999 A.N. Richards Award (1999) (0)
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