Ian S. Trowbridge
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Ian S. Trowbridgephilosophy Degrees
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Ian S. Trowbridgebiology Degrees
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Immunology
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Philosophy Biology
Ian S. Trowbridge's Degrees
- PhD Immunology Stanford University
- Doctorate Medicine Stanford University
Why Is Ian S. Trowbridge Influential?
(Suggest an Edit or Addition)Ian S. Trowbridge's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. (1994) (775)
- Signal-dependent membrane protein trafficking in the endocytic pathway. (1993) (700)
- Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin. (1981) (632)
- Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells (1983) (600)
- Transferrin receptors in human tissues: their distribution and possible clinical relevance. (1983) (539)
- Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis (1990) (481)
- Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. (1989) (431)
- Detection of a novel human class II HLA antigen (1983) (375)
- Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. (1982) (319)
- Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit (1985) (293)
- Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization (1990) (279)
- Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells (1981) (274)
- The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid (1982) (269)
- In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella (1994) (264)
- Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200 (1978) (250)
- Biosynthesis of the human transferrin receptor in cultured cells. (1981) (241)
- In Polarized MDCK Cells Basolateral Vesicles Arise from Clathrin-γ-adaptin–coated Domains on Endosomal Tubules (1998) (229)
- The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides (1983) (211)
- Endocytosis and signals for internalization. (1991) (200)
- Characterization of Sorting Signals in the β-Amyloid Precursor Protein Cytoplasmic Domain (*) (1995) (197)
- Structural variants of human T200 glycoprotein (leukocyte‐common antigen). (1987) (197)
- Human cell-surface glycoprotein with unusual properties (1980) (195)
- Human homologue of murine T200 glycoprotein (1980) (194)
- Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. (1989) (191)
- Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment (1994) (184)
- Covalent binding of fatty acid to the transferrin receptor in cultured human cells. (1981) (173)
- A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc: alpha-D-mannoside beta 1,6 N-acetylglucosaminyltransferase. (1982) (167)
- Identification of the intermolecular disulfide bonds of the human transferrin receptor and its lipid‐attachment site. (1987) (161)
- Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. (1993) (153)
- Isolation and chemical characterization of a mitogenic lectin from Pisum sativum. (1974) (148)
- Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism (1996) (144)
- Structural Requirements for Basolateral Sorting of the Human Transferrin Receptor in the Biosynthetic and Endocytic Pathways of Madin-Darby Canine Kidney Cells (1997) (131)
- Transferrin receptors: structure and function. (1984) (131)
- Transferrin receptors promote the formation of clathrin lattices (1991) (123)
- The synthesis and properties of T25 glycoprotein in thy-1-negative mutant lymphoma cells (1978) (123)
- Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck (1990) (123)
- Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1 (1981) (122)
- Differences in the surface proteins of mouse B and T cells. (1975) (122)
- Role of CD44 cytoplasmic domain in hyaluronan binding (1995) (121)
- Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations. (1980) (119)
- Murine cell surface transferrin receptor: Studies with an anti‐receptor monoclonal antibody (1982) (119)
- Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: evidence for synergistic antiproliferative effects. (1990) (116)
- Monoclonal antibody to a membrane glycoprotein inhibits the acrosome reaction and associated Ca2+ and H+ fluxes of sea urchin sperm (1985) (116)
- YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis. (1993) (115)
- CD45. A prototype for transmembrane protein tyrosine phosphatases. (1991) (114)
- Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts. (1995) (111)
- Sorting Mechanisms Regulating Membrane Protein Traffic in the Apical Transcytotic Pathway of Polarized MDCK Cells (1998) (109)
- Rate of 59Fe Uptake into Brain and Cerebrospinal Fluid and the Influence Thereon of Antibodies Against the Transferrin Receptor (1993) (88)
- B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing. (1987) (88)
- Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester. (1984) (85)
- Transplanted LDL and mannose‐6‐phosphate receptor internalization signals promote high‐efficiency endocytosis of the transferrin receptor. (1991) (84)
- Structure of the lipid-linked oligosaccharides that accumulate in class E Thy-1-negative mutant lymphomas (1979) (82)
- Effects of anti‐transferrin receptor antibodies on growth of normal and malignant myeloid cells (1983) (82)
- Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues (1982) (78)
- Immunoglobulin-like nature of the α-chain of a human T-cell antigen/MHC receptor (1984) (77)
- CD45: a leukocyte-specific member of the protein tyrosine phosphatase family. (1991) (77)
- Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus. (1983) (73)
- A monoclonal antibody useful for the differential diagnosis between malignant lymphoma and nonhematopoietic neoplasms (1983) (72)
- Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia. (1981) (71)
- A lectin-resistant mouse lymphoma cell line is deficient in glucosidase II, a glycoprotein-processing enzyme. (1982) (69)
- Inhibition of human lymphocyte proliferation by monoclonal antibody to transferrin receptor. (1983) (68)
- Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. (1992) (68)
- Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate. (2006) (67)
- Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase. (1992) (66)
- Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene (1985) (66)
- Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies (1989) (66)
- Monoclonal antibodies against defined epitopes of the human transferrin receptor cytoplasmic tail. (1992) (66)
- Participation of histocompatibility antigens in capping of molecularly independent cell surface components by their specific antibodies. (1978) (66)
- Identification of lymphocyte integral membrane proteins as substrates for protein kinase C. Phosphorylation of the interleukin-2 receptor, class I HLA antigens, and T200 glycoprotein. (1986) (66)
- T200 cell surface glycoprotein of the mouse. Polymorphism defined by the Ly-5 system of alloantigens (1980) (64)
- p180, a novel recycling transmembrane glycoprotein with restricted cell type expression (1990) (61)
- Disposition of T200 glycoprotein in the plasma membrane of a murine lymphoma cell line. (1980) (58)
- High molecular weight lymphocyte surface proteins are structurally related and are expressed on different cell populations at different times during lymphocyte maturation and differentiation. (1982) (58)
- Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200 (1986) (55)
- Thy-1 variants of mouse lymphomas: biochemical characterization of the genetic defect (1975) (54)
- Mouse lymphoma cell lines resistant to pea lectin are defective in fucose metabolism. (1980) (52)
- Abnormal lipid-linked oligosaccharides in class E thy-1-negative mutant lymphomas (1979) (51)
- Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies. (1986) (50)
- Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 cell clones (1991) (49)
- Transferrin receptor as a potential therapeutic target. (1988) (45)
- Nonacylated human transferrin receptors are rapidly internalized and mediate iron uptake. (1990) (43)
- Selection and properties of a mouse L-cell transformant expressing human transferrin receptor (1983) (41)
- Effects of monoclonal antibodies that block transferrin receptor function on the in vivo growth of a syngeneic murine leukemia. (1987) (41)
- Effect of an anti-murine transferrin receptor-ricin A conjugate on bone marrow stem and progenitor cells treated in vitro. (1984) (40)
- Characterization of the human transferrin receptor produced in a baculovirus expression system. (1988) (39)
- Structure and function of transferrin receptors and their relationship to cell growth. (1986) (38)
- Analysis of lymphocyte surface antigen expression by the use of variant cell lines. (1977) (37)
- Mitogenic Properties of Pea Lectin and Its Chemical Derivatives (1973) (36)
- Functional analysis of human/chicken transferrin receptor chimeras indicates that the carboxy-terminal region is important for ligand binding. (1996) (35)
- Expression of Thy‐1 glycoprotein on lectin‐resistant lymphoma cell lines (1978) (32)
- Structural Requirements for Major Histocompatibility Complex Class II Invariant Chain Trafficking in Polarized Madin-Darby Canine Kidney Cells* (1997) (32)
- Preliminary characterization of two thymus-dependent xenoantigens from mouse lymphocytes. (1977) (30)
- Regulation of CD45 expression in human leukemia cells. (1991) (29)
- The role of transferrin receptors and iron delivery in mouse embryonic morphogenesis. (1985) (29)
- Regulation of transferrin receptor expression in myeloid leukemia cells. (1987) (29)
- Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor (1984) (28)
- Signal-dependent Trafficking of β-Amyloid Precursor Protein-Transferrin Receptor Chimeras in Madin-Darby Canine Kidney Cells* (1998) (27)
- Structural heterogeneity of human Pgp-1 and its relationship with p85 (2004) (25)
- Human B cell line deficient in the expression of B cell‐specific glycoproteins (GP 27,35) (1977) (22)
- The cDNA sequence and primary structure of the chicken transferrin receptor. (1991) (21)
- MEMBRANE PROTEIN TRAFFICKING IN THE ENDOCYTIC PATHW A Y (1993) (20)
- Identification and characterization of the human Pgp-1 glycoprotein (2004) (20)
- Induction in vitro of Hapten Specific Plaque Forming Cells (1970) (20)
- Analysis of the Structural Requirements for Lysosomal Membrane Targeting Using Transferrin Receptor Chimeras* (1998) (18)
- Effects of succinyl-con A on the growth of normal and transformed cells (1974) (18)
- Changes in gene expression induced by a phorbol diester: expression of IL 2 receptor, T3, and T cell antigen receptor. (1987) (17)
- Immune phenotype heterogeneity in AML. (2009) (15)
- Genetic characterization of a polymorphic murine cell-surface glycoprotein (1982) (14)
- Ligand-stimulated tyrosine phosphorylation of the IL-2 receptor beta chain and receptor-associated proteins. (1991) (14)
- Monoclonal Antibodies to Transferrin Receptors (1984) (14)
- Dynamin, SH3 domains and endocytosis (1993) (13)
- Interleukin-2 receptor proteins (1987) (12)
- Localization of T25 glycoprotein in wild-type and Thy 1- mutant cells by immunofluorescence and immunoelectron microscopy (1978) (12)
- Recombinant Rous sarcoma virus vectors for avian cells. (1994) (11)
- Structural requirements for high efficiency endocytosis of the human transferrin receptor. (1992) (11)
- Transferrin receptor as a target for antibody-drug conjugates. (1985) (10)
- Structure and function of CD45: a leukocyte-specific protein tyrosine phosphatase. (1992) (10)
- Monoclonal antibodies to transferrin receptor and assay of their biological effects. (1987) (10)
- Cell surface molecules of friend erythroleukemias: Decrease in T200 glycoprotein expression after induction (1980) (9)
- Revertant expressing a structural variant of T200 glycoprotein (2004) (9)
- The enhancement of a primary in vitro anti‐hapten response by carrier priming (1972) (8)
- Coclustering CD 45 with CD 4 or CD 8 Alters the Phosphorylation and Kinase Activity of p 56 " By (2003) (8)
- Evidence for two extracellular domains in the human interleukin‐2 receptor: localization of IL‐2 binding. (1986) (8)
- Regulation and structure-function relationship of CD45. (1992) (8)
- High level expression and purification of the enzymatically active cytoplasmic region of human CD45 phosphatase from yeast. (1994) (8)
- Structure-Function Analysis of the Human Transferrin Receptor: Effects of Anti-Receptor Monoclonal Antibodies on Tumor Growth1 (1991) (7)
- Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor. (1984) (7)
- Modulation of p 36 Phosphorylation in Human Cells : Studies Using Anti-p 36 Monoclonal Antibodies (6)
- CONTROL OF GROWTH OF MAMMALIAN CELLS (1975) (5)
- Monoclonal Antibodies Directed towards Growth-Related Receptors on Human Tumors (1985) (5)
- Immunoelectron microscopic localization of Thy-1 glycoprotein in wild type and Thy-1-negative lymphoma cells. (1982) (5)
- Structure-function analysis of the human transferrin receptor: effects of anti-receptor monoclonal antibodies on tumor growth. (1991) (4)
- Disposition of T 200 Glycoprotein in the Plasma Membrane of a Murine Lymphoma Cell Line (2001) (4)
- Two complementation classes of T200 (Ly-5) clycoprotein-negative mutants (1981) (4)
- Evidence for Conformational Changes in Concanavalin A Upon Binding of Saccharides as Determined from Solvent Water Proton Magnetic Relaxation Rate Dispersion Measurements (1975) (4)
- Structural studies of T200 glycoprotein and the IL-2 receptor. (1987) (4)
- A Mouse Lymphoma Cell Line Resistant to the Leukoagglutinating Lectin from Phaseolus vulgaris Is Deficient in UDP-G~CNAC:CX-D- (1982) (3)
- The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. (2006) (2)
- A Lectin-resistant Mouse Lymphoma Cell Line Is Deficient in Glucosidase 11, a Glycoprotein-processing Enzyme* (Received for publication, March 29, 1982) (1982) (2)
- Cell surface receptors that serve to transport ligands. (1989) (2)
- Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302. (2006) (1)
- Immunoassay of serum transferrin receptors: clinical implications. (1989) (1)
- Pea lectin resistant mouse lymphoma cell lines are defective in fucose metabolism. Abstr. (1980) (1)
- Aspects of tumour biology (1976) (1)
- Cancer monoclonals (1981) (0)
- Isolation and Chemical Characterization of a Mitogenic Lectin from Pisum satiwum* (2003) (0)
- Comparison of [ anS ] Methionine T ~ yptic Peptides from Murine T 200 and the Glycoprotein of Human Lymphoid Cells (2003) (0)
- OMARY , TROWBRIDGE , AND SCHEID (2003) (0)
- Mitogenic properties of lectin and its chemical dervatives. (1973) (0)
- Bricf Detlnitive Rcport (2003) (0)
- Dyntamin, SH3 domains and endocytosis The GTP-binding protein dynamin may regulate receptor-mediated endocytosis by interacting with the SH3 domain of an activator protein, (1993) (0)
- Xenoantigens from mouse lymphocytes. (1977) (0)
- Monoclonal antibody to transferrin binding and inhibits human tumor (iron starvation/leukemic cells) (2016) (0)
- Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies (1986) (0)
- Patents and literature (1985) (0)
- Immunoregulatory molecules and their modes of action: 22nd Midwinter Conference of Immunologists Pacific Grove, California, January 22–25, 1983☆ (1983) (0)
- (iodination/lymphocytes/mitogens/polyacrylamide gels/. (2016) (0)
- Cell surface antigen Thy-1. Immunology, neurology, and therapeutic applications Edited by A. E. Reif and M. Schlesinger. New York: Marcel Dekker, Inc. (1989). 618 pp. $165.00 (1989) (0)
- Monoclonal antibodies (mAb) ~ directed against a T lymphocyte membrane protein complex having characteristics predicted for the T lymphocyte antigen (2003) (0)
- Signals for Receptor-Mediated Endocytosis (1993) (0)
- MONOCLONAL ANTIBODIES AND CANCER (1982) (0)
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