Ian R. Kimber

Q: What Schools Are Affiliated With Ian R. Kimber

Ian R. Kimber is affiliated with the following schools: University of Liverpool, Liverpool John Moores University, University of Manchester

Ian R. Kimber's AcademicInfluence.com Rankings

Ian R. Kimber

Chemistry

#1689

World Rank

#2464

Historical Rank

Organic Chemistry

#214

World Rank

#267

Historical Rank

chemistry Degrees

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Chemistry

Ian R. Kimber's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Ian R. Kimber's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization. (2007) (1043)
Allergic Contact Dermatitis (1998) (679)
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 (2011) (536)
Natural killer cells. (1985) (493)
Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods (2005) (431)
Immunogenicity of therapeutic proteins: Influence of aggregation (2013) (408)
Langerhans cells require signals from both tumour necrosis factor‐α and interleukin‐1β for migration (1997) (371)
Food processing and allergenicity. (2015) (363)
Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration. (1992) (353)
Assessment of the safety of foods derived from genetically modified (GM) crops. (2004) (335)
Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. (2011) (304)
The murine local lymph node assay: a commentary on collaborative studies and new directions. (1992) (277)
Tumour necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization. (1995) (272)
Why are some proteins allergens? (2000) (246)
Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy (2012) (245)
Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects (2011) (235)
The local lymph node assay: developments and applications. (1994) (232)
Epicutaneous exposure to peanut protein prevents oral tolerance and enhances allergic sensitization (2005) (228)
A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses (1999) (223)
REVIEWCytokines and chemokines in the initiation and regulation of epidermal Langerhans cell mobilization (2000) (220)
Classification of contact allergens according to potency: proposals. (2003) (218)
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing. (2012) (214)
Use of the local lymph node assay for the estimation of relative contact allergenic potency (2000) (213)
Local lymph node assay: validation assessment for regulatory purposes. (2000) (198)
The local lymph node assay: past, present and future (2002) (195)
The local lymph node assay: a viable alternative to currently accepted skin sensitization tests. (1996) (190)
α6 Integrins Are Required for Langerhans Cell Migration from the Epidermis (1997) (185)
Further evaluation of the local lymph node assay in the final phase of an international collaborative trial. (1996) (185)
Interleukin (IL)‐18 induces Langerhans cell migration by a tumour necrosis factor‐α‐ and IL‐1β‐dependent mechanism (2001) (181)
Allergic contact dermatitis: the cellular effectors (2002) (176)
A future approach to measuring relative skin sensitising potency: a proposal (2006) (174)
The murine local lymph node assay. (1995) (171)
Contact allergenic potency: correlation of human and local lymph node assay data. (2001) (169)
Local Lymph Node Data for the Evaluation of Skin Sensitization Alternatives: A Second Compilation (2010) (166)
An assessment of the ability of phthalates to influence immune and allergic responses. (2010) (163)
Local lymph node assay - validation, conduct and use in practice. (2002) (160)
An international evaluation of the murine local lymph node assay and comparison of modified procedures. (1995) (159)
Regulation of mouse peritoneal mast cell secretory function by stem cell factor, IL-3 or IL-4. (1993) (158)
Langerhans cell migration (2000) (156)
Differential stimulation of immune function by respiratory and contact chemical allergens. (1991) (152)
Skin sensitization testing in potency and risk assessment. (2001) (150)
Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response (2004) (146)
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma (2003) (145)
Consensus report on the future of animal-free systemic toxicity testing. (2014) (144)
Chemical allergy: translating biology into hazard characterization. (2011) (143)
Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-alpha. (1994) (143)
Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice. (1996) (139)
The murine local lymph node assay for identification of contact allergens: a preliminary evaluation of in situ measurement of lymphocyte proliferation (1989) (138)
Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals. (2007) (138)
Challenges and approaches for the development of safer immunomodulatory biologics (2013) (138)
The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses. (2006) (135)
Predictive identification of human skin sensitization thresholds (2005) (132)
Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells. (1998) (132)
Intracellular Phosphotyrosine Induction by Major Histocompatibility Complex Class II Requires Co-aggregation with Membrane Rafts* (1999) (130)
Development of a murine local lymph node assay for the determination of sensitizing potential (1986) (129)
A chemical dataset for evaluation of alternative approaches to skin‐sensitization testing (2004) (127)
The multiple factors affecting the association between atopic dermatitis and contact sensitization (2014) (126)
A novel model of sensitization and oral tolerance to peanut protein (2004) (126)
Impaired Langerhans cell migration in psoriasis (2006) (126)
A murine local lymph node assay for the identification of contact allergens (2004) (126)
Dendritic cells and cutaneous immune responses to chemical allergens. (1992) (123)
Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure. (1994) (123)
The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test. (1994) (123)
Functional Caspase-1 Is Required for Langerhans Cell Migration and Optimal Contact Sensitization in Mice1 (2001) (123)
Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation (2005) (122)
Phenotypic Anchoring of Gene Expression Changes during Estrogen-Induced Uterine Growth (2004) (121)
Investigation of lymph node cell proliferation as a possible immunological correlate of contact sensitizing potential. (1991) (120)
Cytokines and Langerhans cell mobilisation in mouse and man. (2005) (116)
Structure activity relationships in skin sensitization using the murine local lymph node assay. (1995) (116)
The murine local lymph node assay: results of an inter-laboratory trial. (1991) (114)
Toll‐like receptor ligand activation of murine bone marrow‐derived dendritic cells (2009) (114)
Influence of sodium lauryl sulphate on 2,4-dinitrochlorobenzene-induced lymph node activation. (1993) (112)
Cell and molecular biology of chemical allergy (1997) (112)
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens (1996) (112)
Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation. (1999) (112)
Role of tumour necrosis factor-alpha in ultraviolet B light-induced dendritic cell migration and suppression of contact hypersensitivity. (1994) (110)
Tumour necrosis factor‐α‐induced migration of human Langerhans cells: the influence of ageing (2002) (109)
Activity of human contact allergens in the murine local lymph node assay (2000) (109)
Stimulation of Langerhans Cell Migration by Tumor Necrosis Factor α (TNF-α) (1992) (106)
Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone (1992) (104)
Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen. (2004) (104)
The principles and practice of toxigenomics: applications and opportunities. (2000) (104)
Strategies for identifying false positive responses in predictive skin sensitization tests. (1998) (102)
The local lymph node assay and the assessment of relative potency: status of validation (2007) (101)
IL‐1β‐induced Langerhans’ cell migration and TNF‐α production in human skin: regulation by lactoferrin (2003) (101)
Interlaboratory Evaluation of the Local Lymph Node Assay with 25 Chemicals and Comparison with Guinea Pig Test Data (1991) (98)
Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64. (2008) (98)
Dendritic Cells as a Tool for the Predictive Identification of Skin Sensitisation Hazard (2005) (97)
IL‐18 is a key proximal mediator of contact hypersensitivity and allergen‐induced Langerhans cell migration in murine epidermis (2008) (96)
Contact sensitization: A new approach to risk assessment (1997) (95)
Anti-proliferative effect of estrogen in breast cancer cells that re-express ERalpha is mediated by aberrant regulation of cell cycle genes. (2005) (95)
Langerhans cells and chemical allergy. (1998) (95)
Local lymph node assay: use in hazard and risk assessment (1999) (94)
The effect of ultraviolet B irradiation and urocanic acid isomers on dendritic cell migration. (1992) (93)
Variable effects of chemical allergens on serum ige concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers (1992) (91)
Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses. (2002) (89)
Assessment of the skin sensitization potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation. (1998) (89)
Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure. (2002) (89)
Local lymph node assay responses to paraphenylenediamine: intra‐ and inter‐laboratory evaluations (1999) (89)
Regulation of epidermal Langerhans cell migration by lactoferrin (2000) (89)
Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response. (2004) (87)
Interleukin 1β and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor α (1997) (87)
Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides (1999) (85)
Dendritic cell accumulation in draining lymph nodes during the induction phase of contact allergy in mice. (1989) (85)
Role of CD4+ T helper 2‐type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate (2000) (84)
Determination of protein allergenicity: studies in mice. (2001) (84)
Exogenous topical lactoferrin inhibits allergen‐induced Langerhans cell migration and cutaneous inflammation in humans (2001) (84)
The safety of genetically modified foods produced through biotechnology. (2003) (83)
Divergent antibody isotype responses induced in mice by systemic exposure to proteins: a comparison of ovalbumin with bovine serum albumin. (2000) (83)
Classification of Chemical Allergens According to Cytokine Secretion Profiles of Murine Lymph Node Cells (1997) (81)
Chemical Reactivity Measurement and the Predictive Identification of Skin Sensitisers (2008) (81)
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens. (2002) (81)
Identification of contact allergens using the murine local lymph node assay: Comparisons with the buehler occluded patch test in guinea pigs (1990) (80)
Langerhans cells require signals from both tumour necrosis factor alpha and interleukin 1 beta for migration. (1997) (80)
Thresholds in contact sensitization: theoretical and practical considerations. (1999) (80)
Epidermal Langerhans cell migration and sensitisation to chemical allergens (2003) (79)
An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential (2007) (79)
Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment. (2005) (78)
MHC class II expression by Langerhans' cells and lymph node dendritic cells: possible evidence for maturation of Langerhans' cells following contact sensitization. (1991) (78)
Development of non-radio isotopic endpoint of murine local lymph node assay based on 5-bromo-2'-deoxyuridine (BrdU) incorporation. (2001) (78)
Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay. (2002) (77)
Human potency predictions for aldehydes using the local lymph node assay (2001) (77)
Chemical Respiratory Allergy: Opportunities for Hazard Identification and Characterisation (2007) (76)
Cytokine fingerprinting and hazard assessment of chemical respiratory allergy (2001) (76)
Investigation of induced changes in interleukin 1beta mRNA expression by cultured human dendritic cells as an in vitro approach to skin sensitization testing. (2000) (76)
The local lymph node assay: Results of a final inter‐laboratory validation under field conditions (1992) (76)
The Need to Decide If All Estrogens Are Intrinsically Similar (2004) (75)
Chemical allergy: considerations for the practical application of cytokine profiling. (2003) (75)
Phenotypic characteristics of antigen-bearing cells in the draining lymph nodes of contact sensitized mice. (1990) (74)
Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays. (1993) (73)
Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin‐1β (2002) (73)
Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure. (2001) (73)
Allergen‐induced changes in interleukin 1β (iL‐1β) mRNA expression by human blood‐derived dendritic cells: inter‐individual differences and relevance for sensitization testing (2001) (72)
Adverse Outcome Pathways can drive non-animal approaches for safety assessment (2015) (71)
Toxicology of protein allergenicity: prediction and characterization. (1999) (70)
Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing. (2006) (70)
Examination of a vehicle for use with water soluble materials in the murine local lymph node assay. (2002) (69)
Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens. (1995) (68)
Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses. (2002) (68)
Lactoferrin: influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation. (2002) (67)
The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay (2001) (67)
Protein digestibility and relevance to allergenicity. (2003) (67)
Alternative approaches to the identification and characterization of chemical allergens. (2001) (66)
Assessing the potential to induce respiratory hypersensitivity. (2006) (66)
Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium (2005) (65)
Animal models of protein allergenicity: potential benefits, pitfalls and challenges (2009) (65)
Skin Sensitisation and Epidermal Disposition: The Relevance of Epidermal Disposition for Sensitisation Hazard Identification and Risk Assessment (2007) (65)
A primer on systematic reviews in toxicology (2017) (65)
Potency values from the local lymph node assay: application to classification, labelling and risk assessment. (2010) (65)
Characterization of a monoclonal antibody to cis-urocanic acid: detection of cis-urocanic acid in the serum of irradiated mice by immunoassay. (1993) (64)
Gene ontology mapping as an unbiased method for identifying molecular pathways and processes affected by toxicant exposure: application to acute effects caused by the rodent non-genotoxic carcinogen diethylhexylphthalate. (2005) (64)
Skin sensitisation, vehicle effects and the local lymph node assay. (2001) (63)
Systemic migration of dendritic cells during contact sensitization. (1990) (63)
T helper cell 2 immune skewing in pregnancy/early life: chemical exposure and the development of atopic disease and allergy (2015) (62)
Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area. (2008) (62)
Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde. (1998) (62)
Constitutive and inducible expression of interleukin‐6 by Langerhans cells and lymph node dendritic cells (1996) (61)
The direct peptide reactivity assay: selectivity of chemical respiratory allergens. (2012) (61)
A mouse model for food allergy using intraperitoneal sensitization. (2007) (61)
Chemical respiratory allergy: reverse engineering an adverse outcome pathway. (2014) (61)
What makes a chemical a respiratory sensitizer? (2005) (60)
The rapid rejection of allogeneic lymphocytes by a non-adaptive, cell-mediated mechanism (NK activity). (1985) (60)
Characterization in mice of the immunological properties of five allergenic acid anhydrides (2000) (59)
Evaluation of protein allergenic potential in mice: dose–response analyses (2003) (59)
Dendritic cells and skin sensitization: biological roles and uses in hazard identification. (2007) (59)
Influence of chronic low-level exposure to lead on plasma immunoglobulin concentration and cellular immune function in man (1986) (59)
Cytokines in non-genotoxic hepatocarcinogenesis. (1999) (58)
Impact of Cutaneous IL-10 on Resident Epidermal Langerhans’ Cells and the Development of Polarized Immune Responses (2005) (58)
Cytokine fingerprinting: characterization of chemical allergens. (1999) (57)
Characterization of murine immune responses to allergenic diisocyanates. (1992) (57)
Sensitization to 2,4-dinitrochlorobenzene: influence of vehicle on absorption and lymph node activation. (1996) (57)
Alternative Methods for Skin Sensitisation Testing (1996) (56)
Assessment of protein allergenicity on the basis of immune reactivity: animal models. (2002) (56)
Regulation of expression of the novel IL‐1 receptor family members in the mouse brain (2005) (56)
Interleukin‐1‐induced interleukin‐6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones (2008) (56)
The bronchial epithelium in asthma--much more than a passive barrier. (2001) (55)
Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: an analysis using the local lymph node assay (1999) (55)
Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty? (2008) (54)
Identification of metal allergens in the local lymph node assay. (1999) (53)
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin. (2003) (53)
The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides. (2008) (53)
Selective Haptenation of Cellular or Extracellular Protein by Chemical Allergens: Association with Cytokine Polarization (2005) (53)
Vehicle effects on skin sensitizing potency of four chemicals: assessment using the local lymph node assay (2001) (52)
Toxicology of Contact Hypersensitivity (1996) (52)
Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde (1998) (52)
Chemical reactivity measurements: potential for characterization of respiratory chemical allergens. (2011) (51)
Antigen-bearing dendritic cells in the draining lymph nodes of contact sensitized mice: cluster formation with lymphocytes. (1991) (50)
Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity. (1993) (49)
The local lymph node assay in practice: a current regulatory perspective (2006) (48)
Why does allergic contact dermatitis exist? (2013) (48)
The Mouse IgE Test for the Identification of Potential Chemical Respiratory Allergens: Considerations of Stability and Controls (1996) (48)
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing. (2002) (48)
Current challenges facing the assessment of the allergenic capacity of food allergens in animal models (2016) (47)
The effect of sleep deprivation and exercise on reaction threshold in peanut-allergic adults: a randomised controlled study. (2019) (47)
Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice. (1992) (47)
The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics1 (2009) (47)
Methods for the identiﬁcation of chemical respiratory allergens in rodents: comparisons of cytokine proﬁling with induced changes in serum IgE (2003) (47)
Identification of Chemical Respiratory Allergens: Dose-Response Relationships in the Mouse IgE Test (1995) (46)
Immunotoxicology: suppressive and stimulatory effects of drugs and environmental chemicals on the immune system (2004) (46)
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody. (1991) (46)
Inhibition by dexamethasone of Langerhans cell migration: influence of epidermal cytokine signals. (1999) (46)
Dinitrohalobenzenes: evaluation of relative skin sensitization potential using the local lymph node assay (1997) (46)
The role of the skin in the development of chemical respiratory hypersensitivity. (1996) (45)
Immunogenic properties of rapidly digested food proteins following gavage exposure of mice: a comparison of ovalbumin with a potato acid phosphatase preparation. (2002) (45)
Respiratory allergy: hazard identification and risk assessment. (1994) (45)
Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen‐activated protein kinase (MAPK) inhibitor SB203580 (2004) (45)
Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH (2009) (45)
Predictive Tests for Irritants and Allergens and Their Use in Quantitative Risk Assessment (2011) (44)
The expanding interleukin-1 family and its receptors (2003) (44)
Allergic contact dermatitis: a commentary on the relationship between T lymphocytes and skin sensitising potency. (2012) (43)
Skin sensitisation testing--new perspectives and recommendations. (2001) (43)
Updating the skin sensitization in vitro data assessment paradigm in 2009 (2009) (43)
Intercellular adhesion molecule-1 (ICAM-1) expression by lymph node dendritic cells: comparison with epidermal Langerhans cells. (1992) (43)
Measurement of allergenic potency using the local lymph node assay. (2001) (43)
Differential effects of UVA1 and UVB radiation on Langerhans cell migration in mice. (2000) (43)
Characteristics of antibody responses induced in mice by protein allergens. (1997) (42)
The role of dendritic cells in cutaneous immunity (1996) (42)
What makes a chemical an allergen? (2003) (42)
Developing a framework for assessing chemical respiratory sensitization: A workshop report. (2016) (41)
Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization (2013) (41)
Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome* (2014) (41)
The local lymph node assay and skin sensitization: a cut‐down screen to reduce animal requirements? (2006) (40)
Stimulation of Langerhans cell migration by tumor necrosis factor alpha (TNF-alpha). (1992) (40)
Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones (2008) (40)
Toxicology of Contact Dermatitis: Allergy, Irritancy and Urticaria (1999) (40)
Inter‐relationships between different classes of chemical allergens (2013) (40)
Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization. (1994) (39)
Extrapolating Local Lymph Node Assay EC3 Values To Estimate Relative Sensitizing Potency (2007) (39)
Induction of IgE antibody responses by protein allergens: inter-laboratory comparisons. (2003) (39)
Sulphanilic acid: divergent results in the guinea pig maximization test and the local lymph node assay (1992) (39)
Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens. (1994) (39)
Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease. (2011) (39)
Workshop overview. Identification of respiratory allergens. (1996) (39)
Influence of dibutyl phthalate on dermal sensitization to fluorescein isothiocyanate. (1996) (38)
Langerhans cell migration in mice requires intact type I interleukin 1 receptor (IL-1RI) function (1999) (38)
Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea‐pig data and human experience (2006) (38)
The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce IL-1beta signalling responses. (2005) (38)
Interleukin 1 beta and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor alpha. (1997) (38)
Aligning the 3Rs with new paradigms in the safety assessment of chemicals. (2015) (38)
Oral tolerance to contact allergens: a common occurrence? A review (2007) (37)
Chemical allergens--what are the issues? (2010) (37)
Influence of plant lipids on immune responses in mice to the major Brazil nut allergen Ber e 1 (2007) (37)
Thresholds in chemical respiratory sensitisation. (2015) (37)
Differential immunogenicity and allergenicity of native and recombinant human lactoferrins: Role of glycosylation (2013) (37)
The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay. (1999) (37)
The Hapten‐Atopy hypothesis II: the ‘cutaneous hapten paradox’ (2011) (36)
Toxicogenomics; transcript profiling and potential application to chemical allergy. (2002) (36)
Identification of a truncated IL-18Rβ mRNA: a putative regulator of IL-18 expressed in rat brain (2003) (36)
Workshop overview: approaches to the assessment of the allergenic potential of food from genetically modified crops. (2003) (36)
Cytokines and regulation of allergic sensitization to chemicals. (1994) (35)
Toxicogenetics: applications and opportunities. (2003) (35)
Assessing the potency of respiratory allergens: uncertainties and challenges. (2011) (35)
Identification of Respiratory Allergens (1996) (35)
Acne, quorum sensing and danger (2014) (35)
Food allergy: what are the issues? (2001) (35)
Inhibition of CD23‐dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules (2010) (35)
Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway. (2018) (34)
Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarization. (2005) (34)
Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients. (2012) (34)
Identification of a possible association between carbon tetrachloride–induced hepatotoxicity and interleukin‐8 expression (2000) (34)
Correlation between lymphocyte proliferative responses and dendritic cell migration in regional lymph nodes following skin painting with contact-sensitizing agents. (1990) (34)
Measurement of cytokine expression and Langerhans cell migration in human skin following suction blister formation (2004) (33)
Pathology considerations for, and subsequent risk assessment of, chemicals identified as immunosuppressive in routine toxicology. (1995) (33)
Dendritic cells and skin sensitisation hazard assessment. (2004) (33)
Contact sensitization of mice to nickel sulphate and potassium dichromate (1990) (33)
Selective induction of type 2 cytokines following topical exposure of mice to platinum salts. (1998) (33)
Induced changes in total serum IgE concentration in the Brown Norway rat: potential for identification of chemical respiratory allergens (2002) (33)
Identification of dendritic cells as a major source of interleukin-6 in draining lymph nodes following skin sensitization of mice. (1995) (32)
Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals. (1997) (32)
Induction of iron homeostasis genes during estrogen-induced uterine growth and differentiation (2006) (32)
Immune Responses: Adverse Versus Non-Adverse Effects (2002) (32)
Thalidomide: lack of mutagenic activity across phyla and genetic endpoints. (1997) (32)
Immune responses to contact allergens: novel approaches to hazard evaluation. (1999) (32)
A critique of the World Resources Institute's report "Pesticides and the immune system: the public health risks". (1998) (32)
Selection of Chemicals for the Development and Evaluation of In Vitro Methods for Skin Sensitisation Testing (2009) (32)
Allergy, asthma and the environment: an introduction. (1998) (31)
Aspects of the immune response to contact allergens: opportunities for the development and modification of predictive test methods. (1989) (31)
Factors affecting the development of food allergy (2002) (31)
Cytokine Production by CD4+ and CD8+ T Cells in Mice following Primary Exposure to Chemical Allergens: Evidence for Functional Differentiation of T Lymphocytes in vivo (1998) (31)
Skin sensitization, false positives and false negatives: experience with guinea pig assays (2010) (31)
THE MOUSE IgE TEST: INTERLABORATORY EVALUATION AND COMPARISON OF BALB/c AND C57BL/6 STRAIN MICE (1998) (31)
Evaluation of an in vitro method for the measurement of specific IgE antibody responses: the rat basophilic leukemia (RBL) cell assay. (2005) (31)
Immunoregulation of skin sensitization and regulatory T cells (2012) (31)
An in vitro human skin test for assessing sensitization potential (2016) (31)
Allergen‐induced cytokine phenotypes in mice: role of CD4+ and CD8+ T cell populations (2005) (31)
Interactions of IFN-gamma with IL-3 and IL-4 in the regulation of serotonin and arachidonate release from mouse peritoneal mast cells. (1994) (30)
Approaches to assessment of the allergenic potential of novel proteins in food from genetically modified crops. (2002) (30)
Proteomic analysis of suction blister fluid isolated from human skin (2006) (30)
Regulation of lymphocyte proliferation in contact sensitivity: homeostatic mechanisms and a possible explanation of antigenic competition. (1989) (30)
Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay (2007) (30)
Experimental assessment of the sensitizing properties of formaldehyde. (1996) (29)
Editor’s Highlight: Subvisible Aggregates of Immunogenic Proteins Promote a Th1-Type Response (2016) (29)
Anamnestic responses to contact allergens: Application in the murine local lymph node assay (1991) (29)
Selective down-regulation of T cell- and non-T cell-derived tumour necrosis factor alpha by thalidomide: comparisons with dexamethasone. (1999) (29)
Identification of early molecular pathways affected by paraquat in rat lung. (2006) (29)
Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones (2008) (29)
Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay. (2001) (29)
Diet and the aetiology of temporal advances in human and rodent sexual development (2000) (28)
Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens (1998) (28)
Exogenous interleukin‐1β restores impaired Langerhans cell migration in aged skin (2004) (28)
The Local Lymph Node Assay (LLNA) (2012) (28)
Respiratory Allergy: Hazard Identification and Risk Assessment (1994) (28)
Langerhans cell mobilization distinguishes between early-onset and late-onset psoriasis. (2010) (28)
An Evaluation of Performance Standards and Non-radioactive Endpoints for the Local Lymph Node Assay (2008) (28)
Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary (1998) (28)
Does hapten exposure predispose to atopic disease? The hapten-atopy hypothesis. (2009) (28)
IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure. (2002) (28)
Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo (2000) (28)
Evaluation of the Sensitizing Potential of Eugenol and Isoeugenol in Mice and Guinea Pigs (1996) (27)
The kinetics of cytokine production by draining lymph node cells following primary exposure of mice to chemical allergens. (1994) (27)
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides (2002) (27)
The lymphocyte transformation test in allergic contact dermatitis: New opportunities (2016) (27)
Advantage of using CBA/N strain mice in a non‐radioisotopic modification of the local lymph node assay (2006) (27)
Danger signals and skin sensitization (2002) (27)
Cytokine endpoints for the local lymph node assay: consideration of interferon‐γ and interleukin 12 (1999) (27)
The Local Lymph Node Assay: Current Position in the Regulatory Classification of Skin Sensitizing Chemicals (2007) (27)
Gene regulation by IL‐1β independent of IL‐1R1 in the mouse brain (2006) (26)
Assessment of the inherent allergenic potential of proteins in mice. (2003) (26)
Reactivity of chemical respiratory allergens in the Peroxidase Peptide Reactivity Assay. (2013) (26)
Factors governing susceptibility to chemical allergy. (2007) (26)
Di-(2-ethylhexyl) phthalate is without adjuvant effect in mice on ovalbumin. (2008) (26)
Local Lymph Node Assays (2004) (26)
Skin irritation, false positives and the local lymph node assay: a guideline issue? (2011) (26)
Setting Occupational Exposure Limits for Chemical Allergens—Understanding the Challenges (2015) (26)
Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens. (1998) (25)
Assessment of statistic analysis in non-radioisotopic local lymph node assay (non-RI-LLNA) with alpha-hexylcinnamic aldehyde as an example. (2003) (25)
Cytokine regulation of chemical sensitization. (1995) (25)
Reflections on the progress towards non-animal methods for acute toxicity testing of chemicals. (2019) (25)
Correlation of contact sensitizer potency with T cell frequency and TCR repertoire diversity. (2014) (25)
Production and in situ localization of cutaneous tumour necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) following skin sensitization. (1998) (25)
Differential effect of thalidomide and dexamethasone on the transcription factor NF-κB (2001) (24)
The Development of Novel Approaches to the Identification of Chemical and Protein Respiratory Allergens (2008) (24)
Toxicology of Chemical Respiratory Hypersensitivity (1997) (24)
Relationship between protein digestibility and allergenicity: comparisons of pepsin and cathepsin. (2013) (24)
T lymphocyte subpopulations in immunotoxicology (1998) (24)
Concepts in psoriasis: psoriasis and the extracellular matrix (2012) (24)
BTS working party report on in vitro toxicology (1997) (24)
Contact-sensitizing and tolerogenic properties of 2,4-dinitrothiocyanobenzene. (1986) (24)
Characteristics and regulation of the expression of interleukin 1 receptors by murine Langerhans cells and keratinocytes (1998) (24)
The cellular and molecular basis for divergent allergic responses to chemicals. (1992) (24)
Predictive methods for food allergenicity: perspectives and current status. (2000) (24)
Skin sensitization (2015) (24)
Phenotypic variation in mast cell responsiveness to the inhibitory action of nitric oxide (2000) (24)
Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization (2014) (24)
Information derived from sensitization test methods: test sensitivity, false positives and false negatives (2007) (24)
The Aryl Hydrocarbon Receptor: Differential Contribution to T Helper 17 and T Cytotoxic 17 Cell Development (2014) (24)
P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages (2015) (24)
Models for contact sensitization‐novel approaches and future developments (1986) (23)
Contact hypersensitivity induces plasma interleukin 6. (1990) (23)
Protein Allergenicity in Mice (2002) (23)
Potency and risk assessment of a skin‐sensitizing disperse dye using the local lymph node assay (2005) (23)
Factors influencing the induction phase of skin sensitization. (2003) (23)
Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride. (2002) (23)
Predictive testing for respiratory sensitization in the mouse. (1996) (22)
Interleukin-6 production by draining lymph node cells following primary contact sensitisation of mice: relationship to the proliferative response. (1994) (22)
Impaired Langerhans cell migration in psoriasis is due to an altered keratinocyte phenotype induced by interleukin‐17 (2018) (22)
Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens. (1992) (21)
Downregulation of Lactoferrin by PPARα Ligands: Role in Perturbation of Hepatocyte Proliferation and Apoptosis (2002) (21)
Predictive testing in contact all_ergy: facts and future (2001) (21)
Selectivity of IgE responses, mast cell sensitization, and cytokine expression in the immune response of Brown Norway rats to chemical allergens. (1996) (21)
Bisphenol A and immunotoxic potential: A commentary. (2017) (21)
The local lymph node assay: An interlaboratory evaluation of Interleukin 6 (IL‐6) production by draining lymph node cells (1994) (21)
Approaches to the identification and classification of chemical allergens in mice. (1993) (21)
Mannosylation Allows for Synergic (CD44/C‐Type Lectin) Uptake of Hyaluronic Acid Nanoparticles in Dendritic Cells, but Only upon Correct Ligand Presentation (2016) (21)
Management of an Integrated Project (Sens-it-iv) to Develop In Vitro Tests to Assess Sensitisation (2007) (20)
Assessment of cumulative allergen-activated lymph node cell proliferation using flow cytometry. (2003) (20)
Assessment of the allergenic potential of proteins. (2003) (20)
Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation. (2003) (20)
The future trajectory of adverse outcome pathways: a commentary (2018) (20)
A Review on the Potential Role of Basement Membrane Laminin in the Pathogenesis of Psoriasis (2016) (20)
Detection of Allergen-Specific IgE Antibody Responses (2005) (19)
Allergenicity of proteins (1997) (19)
Treatment-Related Restoration of Langerhans Cell Migration in Psoriasis (2013) (19)
Computational chemistry, systems biology and toxicology. Harnessing the chemistry of life: revolutionizing toxicology. A commentary (2011) (19)
The identification of chemicals with sensitizing or immunosuppressive properties in routine toxicology. (1994) (19)
Assessment of allergenic potential of genetically modified foods: an agenda for future research. (2002) (19)
Chemical respiratory allergy. Toxicological and occupational health issues (1995) (19)
Induction of mast cell sensitization by chemical allergens: A comparative study (1993) (19)
Blocking Antibodies: Relationship between IgG4-associated Inhibitory Activity and Clinical Response to Grass-Pollen Immunotherapy (2010) (19)
Mechanism and regulation of natural cytotoxicity. Minireview on cancer research. (1985) (19)
The effect of ageing on phenotype and function of monocyte-derived Langerhans cells (2011) (19)
Thresholds of contact sensitization from disperse dyes in textiles (2005) (18)
Differential function of dendritic cells isolated from blood and lymph nodes. (1994) (18)
Contact and respiratory sensitization by chemical allergens: Uneasy relationships☆ (1995) (18)
The selective peptide reactivity of chemical respiratory allergens under competitive and non-competitive conditions (2013) (18)
Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells. (2005) (18)
Assessment of the skin sensitization potency of eugenol and its dimers using a non‐radioisotopic modiﬁcation of the local lymph node assay (2004) (18)
Reviewing the Utility of Two Species in General Toxicology Related to Drug Development (2018) (18)
Draining lymph node cell activation in guinea pigs: comparisons with the murine local lymph node assay. (1991) (18)
Selective Stimulation of Cutaneous Interleukin 6 Expression by Skin Allergens (1996) (18)
Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin (2017) (18)
The mechanisms and evaluation of chemically induced allergy. (1992) (18)
Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparison (1996) (18)
Workshop on Status of Test Methods for Assessing Potential of Chemicals to Induce Respiratory Allergic Reactions (1994) (17)
Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response. (2004) (17)
Failure of vehicle to influence local lymph node assay response to benzocaine. (2000) (17)
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe. (2009) (17)
Interleukin 6 (IL-6) Production by Lymph Node Cells: An Alternative Endpoint for the Murine Local Lymph Node Assay (1993) (17)
Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice (2009) (16)
Retrospective appraisal of the relationship between skin irritancy and contact sensitization potential. (1995) (16)
Stimulation of Langerhans cell migration in mice by tumour necrosis factor alpha and interleukin 1 beta. (1997) (16)
Cytokine profiling and chemical allergy. (2002) (16)
Differential effect of thalidomide and dexamethasone on the transcription factor NF-kappa B. (2001) (16)
Quantitative risk assessment for skin sensitization: Success or failure? (2017) (16)
Streptozotocin: inherent but not expressed skin sensitizing activity (1995) (16)
The reduced local lymph node assay: the impact of group size (2008) (16)
Differential actions of IL-1 alpha and IL-1 beta in glial cells share common IL-1 signalling pathways (2005) (16)
Assessment of the functional activity of antigen-bearing dendritic cells isolated from the lymph nodes of contact-sensitized mice. (1989) (15)
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation. (2020) (15)
Oxidised adenosine 5′-triphosphate, a P2X7 antagonist, is toxic to rat cerebellar granule neurones in vitro (2001) (15)
Acute-phase proteins and the serological evaluation of experimental contact sensitivity in the mouse. (1989) (15)
Fragrance sensitisers: Is inhalation an allergy risk? (2015) (15)
Chemical pollution, respiratory allergy and asthma: a perspective (2008) (15)
Dichloronitrobenzene: a reappraisal of its skin sensitization potential (1996) (15)
Induction by tumour necrosis factor α of dose-related changes in Langerhans cell frequency in mice (1999) (15)
Can animal models predict food allergenicity (2001) (15)
Modulation of T-helper cell populations: potential mechanisms of respiratory hypersensitivity and immune suppression. (1997) (15)
Utility of historical vehicle‐control data in the interpretation of the local lymph node assay (2003) (15)
Leukocyte migration inhibition in human pulmonary neoplasia. (1977) (15)
Key issues for the assessment of the allergenic potential of genetically modified foods: breakout group reports. (2002) (15)
Food allergy--science and policy needs--The UK Food Standards Agency Research Programme. (2010) (15)
Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection (2020) (15)
Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment. (2019) (15)
Psoriasis and basement‐membrane laminin (2013) (15)
Selection of chemicals for the development and evaluation of in vitro methods for skin sensitisation testing. (2007) (15)
Assessment of the skin sensitising potency of the lower alkyl methacrylate esters. (2014) (15)
Epidermal Langerhans cell migration: signals and mechanisms. (1995) (14)
Epidermal cytokines in contact hypersensitivity: Immunological roles and practical applications. (1993) (14)
Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin* (2015) (14)
Behaviour of chemical respiratory allergens in novel predictive methods for skin sensitisation. (2017) (14)
The local lymph node assay and potential application to the identification of drug allergens. (2001) (14)
Failure of inorganic lead exposure to impair natural killer (NK) cell and T lymphocyte function in rats. (1986) (14)
Distinguishing between adverse and non-adverse effects. Session summary. (2002) (14)
Langerhans cells express human β‐defensin 3: relevance for immunity during skin ageing (2018) (14)
Inter‐laboratory comparisons of assessment of the allergenic potential of proteins in mice (2009) (14)
A re-appraisal of the skin-sensitizing activity of 2,4-dinitrothiocyanobenzene. (1997) (14)
Selective impairment of T lymphocyte activation following contact sensitization with oxazolone. (1991) (14)
Selective Enhancement of Human Mononuclear Leucocyte Cytotoxic Function by Interferon (1981) (14)
Fragrance inhalation and adverse health effects: The question of causation (2019) (13)
Integrating asthma hazard characterization methods for consumer products. (2014) (13)
Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens. (1999) (13)
Influence of Escherichia coli chaperone DnaK on protein immunogenicity (2016) (13)
Dimethylfumarate: potency prediction and clinical experience (2013) (13)
Immunologic basis for autoimmunity and the potential influences of xenobiotics. (2002) (13)
Anti‐hapten antibodies in response to skin sensitization (2016) (13)
Epicutaneous exposure to proteins and skin immune function (2014) (13)
Skin sensitization induced Langerhans’ cell mobilization: variable requirements for tumour necrosis factor‐α (2015) (13)
Reduced allergy rates in atopic eczema to contact allergens used in both skin products and foods: atopy and the ‘hapten‐atopy hypothesis’ (2008) (13)
Characterisation of immune responses to food allergens in mice (2005) (13)
Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation. (2008) (12)
Exposure of UVB‐sensitive mice to immunosuppressive doses of UVB in vivo fails to affect the accessory function or the phenotype of draining lymph node dendritic cells (1996) (12)
Antigenic competition in contact sensitivity. Evidence for changes in dendritic cell migration and antigen handling. (1990) (12)
Regulation of allergic responses to chemicals and drugs: possible roles of epigenetic mechanisms. (2012) (12)
Phthalic anhydride: Illustrating a conundrum in chemical allergy (2016) (12)
Chemical allergy in humans: Fresh perspectives (2014) (12)
The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors (2017) (12)
Identification of B cell epitopes enhanced by protein unfolding and aggregation (2019) (12)
A Modified Murine Local Lymph Node Assay for Identification of Contact Allergens (1989) (12)
“Omics” Technologies and the Immune System (2006) (12)
Chemical respiratory allergy: classification and labelling. (2001) (12)
Toxic shock syndrome: characterization of human immune responses to TSST-1 and evidence for sensitivity thresholds. (2013) (12)
The hapten–atopy hypothesis III: the potential role of airborne chemicals (2014) (12)
Olive oil: suitability for use as a vehicle in the local lymph node assay (1996) (11)
Dendritic cells and the assessment in vitro of skin sensitizing potential (2013) (11)
Langerhans Cell Migration: Initiation and Regulation (1995) (11)
Lymphocyte Circulation: Experimental and Clinical Aspects (1982) (11)
T lymphocyte dynamics in methylisothiazolinone‐allergic patients (2016) (11)
Atopic dermatitis and allergic reactions to individual fragrance chemicals (2009) (11)
Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies (2019) (11)
Skin sensitization quantitative risk assessment for occupational exposure of hairdressers to hair dye ingredients (2018) (11)
The COLIPA strategy for the development of in vitro alternatives: Skin sensitisation (2008) (11)
Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride. (1992) (11)
B220 analysis with the local lymph node assay: proposal for a more flexible prediction model (2007) (11)
Depression of lymph node cell proliferation induced by oxazolone. (1987) (11)
Skin sensitization: Uncertainties, challenges, and opportunities for improved risk assessment (2018) (11)
Perforin and resistance to SARS coronavirus 2 (2020) (11)
Regulation by lactoferrin of epidermal Langerhans cell migration. (1998) (11)
Distinguishing between Adverse and Non-Adverse Effects (2001) (11)
Sodium metabisulfite as a contact allergen – an example of a rare chemical mechanism for protein modification (2012) (10)
1-Chloromethylpyrene: a reference skin sensitizer and genotoxin. (1990) (10)
Attempts to identify the causative allergen in cases of allergic contact dermatitis using an in vitro lymphocyte transformation test. (1990) (10)
Chemical allergen induced perturbations of the mouse lymph node DNA methylome. (2014) (10)
No impairment of monocyte-derived Langerhans cell phenotype or function in early-onset psoriasis (2012) (10)
Designation of substances as skin sensitizing chemicals: a commentary (2003) (10)
Stimulation by oxazolone of increased IL-6, but not IL-10, in the skin of mice. (1996) (10)
Reduction, Refinement and Replacement: Putting the Immune System to Work (2002) (10)
Guttate psoriasis is associated with an intermediate phenotype of impaired Langerhans cell migration (2014) (10)
The effects of interferon on the recirculation of lymphocytes in the rat. (1987) (10)
The activity of methacrylate esters in skin sensitisation test methods: A review (2019) (10)
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response (2009) (9)
The local lymph node assay in 2014. (2014) (9)
Inhibition of antibody-dependent cellular cytotoxicity by artificial immune complexes and pathological sera. (1979) (9)
Immunoglobulin G1 and immunoglobulin G4 antibodies in multiple sclerosis patients treated with IFNβ interact with the endogenous cytokine and activate complement☆ (2013) (9)
The Local Lymph Node Assay (2019) (9)
The Murine Local Lymph Node Assay: Principles and Practice (1993) (9)
Variance in resistance to natural and antibody‐dependent cellular cytotoxicity and to complement‐mediated lysis among K562 lines (1983) (9)
Characterization of the allergenic potential of proteins: an assessment of the kiwifruit allergen actinidin (2014) (9)
Characterization of skin sensitizing chemicals: A lesson learnt from nickel allergy (2011) (9)
Topical Application of TRPA1 Agonists and Brief Cold Exposure Accelerate Skin Permeability Barrier Recovery (2010) (8)
Migration of dendritic cells during contact sensitization. (1993) (8)
Antigen-specific regulation of T lymphocyte proliferative responses to contact-sensitizing chemicals in the guinea pig. (1989) (8)
Surrogate CD16‐expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies (2017) (8)
Household chemicals, immune function, and allergy: A commentary (2013) (8)
Identifying key priorities for research to protect the consumer with food hypersensitivity: A UK Food Standards Agency Priority Setting Exercise (2021) (8)
Workshop: Immunotoxicology and in vitro possibilities. (1994) (8)
Immunotoxicity: hazard identification and risk assessment (1996) (8)
Cytokine profiling of chemical allergens in mice: measurement of message versus protein. (2008) (8)
Investigation of TNF-alpha release as a measure of skin irritancy. (1993) (8)
Examination of Phenotypic Changes in Peripheral Blood‐Derived Dendritic Cells Following Exposure to a Contact Allergen: Cell Surface Marker and Gene Expression (2005) (8)
Oral exposure to mineral oils: Is there an association with immune perturbation and autoimmunity? (2016) (8)
The effects of halothane anaesthesia on antibody-dependent cellular cytotoxicity in rats. (1977) (8)
Azodicarbonamide (ADCA): A reconsideration of classification as a respiratory sensitiser. (2017) (7)
Prediction of drug allergenicity: possible use of the local lymph node assay. (2001) (7)
Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens. (2016) (7)
Toxicology and the Immune System: a Perspective (1991) (7)
Antigen-restricted antigenic competition induced by 2,4-dinitrochlorobenzene: association with depression of lymphocyte proliferation. (1990) (7)
Immunologic Defects in Laboratory Animals (1982) (7)
Migration of interleukin-6 producing Langerhans cells to draining lymph nodes following skin sensitization. (1995) (7)
Using problem formulation to clarify the meaning of weight of evidence and biological relevance in environmental risk assessments for genetically modified crops. (2019) (7)
Production of interleukin-1 by draining lymph node cells during the induction phase of contact sensitization in mice. (1990) (7)
Downregulation of lactoferrin by PPARalpha ligands: role in perturbation of hepatocyte proliferation and apoptosis. (2002) (7)
Perforin, COVID‐19 and a possible pathogenic auto‐inflammatory feedback loop (2021) (7)
Cytokine-mast cell interactions: relevance to IgE-mediated chemical allergy. (1994) (7)
Chemical allergy: molecular mechanisms and practical applications. (1992) (7)
Thresholds, dose–response relationships and dose metrics in allergic contact dermatitis (2008) (6)
The impact of LLNA group size on the identification and potency classification of skin sensitizers: a review of published data (2009) (6)
Use of the kinetically-derived maximum tolerated dose: Opportunities for delivering 3Rs benefits. (2020) (6)
Epidermal cytokines and the induction of allergic and non-allergic contact dermatitis. (1997) (6)
Influence of 12‐o‐tetradecanoylphorbol‐13‐acetate (TPA) on the susceptibility of K562 to natural cytotoxicity: Evidence for clonal variation in differentiation‐induced changes of lytic sensitivity (1984) (6)
alpha 6 integrins are required for Langerhans cell migration. (1997) (6)
The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses. (2020) (6)
Serum histamine and the elicitation of murine contact sensitivity (1991) (6)
Azodicarbonamide (ADCA): A reconsideration of classification as a respiratory sensitiser. (2018) (6)
Cutaneous Cytokine Expression: Induction by Chemical Allergen and Paracrine Regulation (2003) (6)
The evolution of validation: a commentary (2010) (6)
The European Long-range Research Initiative (LRI): A decade of contributions to human health protection, exposure modelling and environmental integrity. (2015) (6)
The cosmetic allergy conundrum: inference of an immunoregulatory response to cosmetic allergens (2013) (6)
Naturally Cytotoxic Tonsillar Lymphocytes: A Manifestation of Heterogeneity among Human NK Cells (1983) (6)
Biomarkers of immunotoxicity in man (1995) (6)
The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies (2019) (6)
Rethinking agrochemical safety assessment: A perspective. (2021) (6)
Lack of immunotoxic effects of repeated exposure to atrazine associated with the adaptation of adrenal gland activation (2017) (6)
Are skin sensitisation test methods relevant for proteins? (2018) (6)
Lysis of alloantibody-sensitized human erythrocytes by peripheral blood mononuclear cells: heterogeneity of effector populations. (1981) (5)
Classification of chemicals as respiratory allergens based on human data: requirements and practical considerations. (2021) (5)
Categorisation of protein respiratory allergens: the case of Subtilisin. (2014) (5)
Inhalation Exposure to Methylene Chloride Does Not Induce Systemic Immunotoxicity in Rats (2003) (5)
The use of ethanol:diethylphthalate as a vehicle for the local lymph node assay (2007) (5)
A preliminary evaluation of immune stimulation following exposure to metal particles and ions using the mouse popliteal lymph node assay. (2016) (5)
Mobilization of epidermal Langerhans cells – reply from the authors (2000) (5)
Antigen-induced unresponsiveness in contact sensitivity: association of depressed T lymphocyte proliferative responses with decreased interleukin 6 secretion. (1996) (5)
Respiratory allergenic potential of plant-derived proteins: Understanding the relationship between exposure and potency for risk assessments (2015) (5)
Determination of the relative allergenic potency of proteins: hurdles and opportunities (2020) (5)
Chemical allergy: Cellular and molecular mechanisms and novel approaches to predictive testing. (1994) (5)
Function of dendritic cells and changes in T cell proliferation in antigen-induced nonresponsiveness. (1992) (5)
Dendritic cell research projects. (2006) (5)
T lymphocyte phenotype of contact‐allergic patients: experience with nickel and p‐phenylenediamine (2019) (4)
Langerhans Cells and Skin Irritation (2006) (4)
Hexyl cinnamal: consideration of skin-sensitizing properties and suitability as a positive control (2015) (4)
AUGMENTATION OF HUMAN NK AND ADCC BY INTERFERON (1980) (4)
Lack of association between interleukin-6 production by contact allergen-activated draining lymph node cells and lymphoproliferative activity. (1998) (4)
Regulation of natural and antibody-dependent cellular cytotoxicity by staphylococcal enterotoxin A. (1983) (4)
Assessment of Allergic Potential (1996) (4)
The influence of 7,12-dimethylbenzanthracene on natural killer (NK) cell function in rats. (1986) (4)
Allergic contact dermatitis: is the reactive chemistry of skin sensitizers the whole story? (2013) (4)
Interleukin‐17 and interleukin‐23 regulate Langerhans cell migration (2016) (4)
Accessory cell requirements for T lymphocyte activation and interferon-gamma production in peripheral lymph nodes. (1996) (4)
Protein Allergenicity: Mouse Models (2002) (4)
Comparison between the phenotype and function of maturing dendritic cells from spleen and lymph nodes (1996) (4)
Native and inducible levels of natural cytotoxicity in lymph nodes draining mammary carcinoma (2004) (4)
Integration of Consortia Recommendations for Justification of Animal Use Within Current and Future Drug Development Paradigms (2019) (4)
The local lymph node assay and skin sensitization testing. (2010) (4)
Immunotoxicology and allergy: Opportunities for in vitro analysis. (1991) (4)
Sensitization of mice to chemical allergens modulates the responsiveness of isolated mast cells to IgE-dependent activation. (1993) (4)
Consideration of criteria required for assignment of a (skin) sensitiser a substance of very high concern (SVHC) under the REACH regulation. (2014) (3)
Antigen-specific and nonspecific determinants of cytokine production during topical sensitization of mice to chemical allergens. (2000) (3)
Re: Updating the Skin Sensitization in Vitro Data Assessment Paradigm in 2009 - a chemistry and QSAR perspective (2010) (3)
Critical evaluation of low-molecular weight respiratory sensitizers and their protein reactivity potential towards lysine residues. (2021) (3)
Transcript Profiling of T Lymphocytes and Dendritic Cells in a Co–culture System Using Anti‐CD3 and Allergen Activation (2004) (3)
Influence of protein expression system on elicitation of IgE antibody responses: experience with lactoferrin. (2012) (3)
Antigen-specific and non-specific depression of proliferative responses induced during contact sensitivity in mice. (1991) (3)
The role of cis-urocanic acid in UVB-induced immunosuppression. (1995) (3)
The use of T cells in hazard characterization of chemical and drug allergens and integration in testing strategies. Foreword. (2014) (3)
Guinea Pig, Mouse, and Rat Models for Safety Assessment of Protein Allergenicity (2005) (3)
Immunotoxicology and allergy: Old problems and new approaches. (1988) (3)
Epidermal cytokines and skin sensitization hazard. (1994) (3)
Interleukin 6 production in vitro: An alternative read-out for the local lymph node assay. (1994) (3)
Contact allergy across the human lifespan. (2020) (3)
Differential susceptibility of haemolysin-sensitized erythrocytes to complement-mediated cytotoxicity: a biological manifestation of the relationship between antibody availability and complement fixation. (1989) (3)
Immunotoxicology of Lead (1990) (3)
The influence of chemical carcinogens on natural killer cell function in rats. A comparison of 2-acetylaminofluorene with 4-acetylaminofluorene. (1986) (3)
Reproductive and developmental toxicology: The value and limitations of in vitro techniques. (1989) (3)
Chemicals in moisturizers may promote type 2 inflammation and food allergy. (2021) (2)
Harnessing co‐operative immune augmentation by contact allergens to enhance the efficacy of viral vaccines (2020) (2)
Keratinocytes derived from late‐onset‐psoriasis skin do not impair Langerhans cell migration (2018) (2)
COMMENTARY Cytokines in non-genotoxic hepatocarcinogenesis (1999) (2)
Epicutaneous exposure to peanut prevents oral tolerance and enhances allergic sensitisation (2004) (2)
FORUM Why Are Some Proteins Allergens (2000) (2)
Quantitative risk assessment for skin sensitization: A simplified approach for hair dye ingredients? (2013) (2)
The XS106 cell: a Langerhans’ cell surrogate with a selective type 2 phenotype (2014) (2)
Immunotoxicology and Allergy: Options for Ex Vivo and In Vitro Experimentation (1991) (2)
Reference Chemical Potency List (RCPL): A new tool for evaluating the accuracy of skin sensitisation potency measurements by New Approach Methodologies (NAMs). (2022) (2)
Enhanced K-cell activity in the peripheral blood of patients with malignant disease (2004) (2)
K cell mediated haemolysis: influence of large numbers of unsensitized cells on the antibody‐dependent lysis of anti‐D‐sensitized erythrocytes by human lymphocytes (1984) (2)
The role of antibody density in the immune lysis of sensitised erythrocytes. A mathematical appreciation. (1989) (2)
Requirements for antigenic competition in contact sensitivity. (1990) (2)
In vivo assays of langerhans cell migration. (2001) (2)
P74 Categorisation of human sensitisation potency using local lymph node assay EC3 values (2004) (2)
Characterization of circulating immune complexes in bronchiectasis by gel filtration (1979) (2)
Immunotoxicological Aspects of Food Allergy (2002) (2)
Prolonged exposure of mice to 2,4-dinitrochlorobenzene (DNCB) results in a Th1/Th17 cytokine fingerprint (2011) (2)
Human K cell-mediated haemolysis: determination of the cytotoxic capacity and antibody sensitization requirements of T lymphocyte enriched and depleted populations. (1983) (2)
Immunotoxicology and Immunopharmacology, Third Edition (2006) (2)
Toxicological aspects of allergic contact dermatitis: report on selected proceedings of the society of toxicology meeting, New Orleans, LA, USA, March 14-18, 1999. (1999) (1)
Immunopharmacology and the regulation of leukocyte function. Immunology series—Vol 19 (1983) (1)
This information is current as Environmental Xenobiotics against Sensitization by Highly Reactive DefensesA Component of the Innate Immune The Cutaneous Biochemical Redox Barrier : and (2009) (1)
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Food Allergy Safety Assessment: An Introduction (2002) (1)
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101 Assessment of the skin sensitization potency of eugenol and its dimers using a non-radioisotopic modification of the local lymph node assay (2003) (1)
Development of the local lymph node assay for risk assessment of chemicals and formulations (2001) (1)
The Use of Cytokines in the Identification and Characterization of Chemical Allergens (2007) (1)
Characterisation of antibody responses induced in mice by food proteins: influence of route of exposure (2000) (1)
Time course transcriptomic analysis of the 17β-estradiol (17βE2)-regulated transcriptome in mouse uterus (1970) (1)
Epidermal cytokines and the induction of allergic and non-allergic contact dermatitis (1996) (1)
Peanut lectin elicits a Th2 cytokine gene expression and protein secretion profile in mice (2002) (1)
Review Food processing and allergenicity (2015) (1)
Reaction thresholds in in peanut‐allergic adults and the influence of exercise and sleep deprivation: a randomised controlled trial: 614 (2019) (1)
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Books Received at the Editorial Office (1986) (1)
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Cytokine Responses Induced by Skin Exposure of Mice to Chemical Allergens: Role of Interleukin 12 (2004) (1)
Reviewing the use of two species in toxicology studies supporting drug development (2018) (1)
The Role of Antibody Density in the Immune Lysis of Sensitised Erythrocytes: A Mathematical Appreciation (1989) (1)
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Allergic Sensitization to Nickel and Implanted Metal Devices: A Perspective (2021) (1)
Synergistic effect of chemical insult and toll-like receptor ligands on dendritic cell activation (2006) (1)
Up-regulation of Granzyme B Gene Expression by Chemical Allergens (2007) (1)
Enzymes and sensitization via skin exposure: A critical analysis. (2021) (1)
Influence of lectin-free interleukin-2 on natural and antibody-dependent cellular cytotoxicity. (1984) (1)
Interleukin-18 is a key mediator of epidermal Langerhans cell migration and contact hypersensitivity in mice. (2002) (1)
Hyperplastic and hypertrophic responses in toxicity and carcinogenesis. (1990) (1)
Methyl methacrylate and respiratory sensitisation: a comprehensive review (2022) (1)
Assessing the severity of allergic reactions: a regulatory dilemma (2012) (1)
Skin Sensitization Tests: The LLNA and the RhE IL-18 Potency Assay. (2021) (1)
Persistent gene expression changes induced by diethylstilbestrol in the neonatal mouse uterus: Role of epigenetics in carcinogenesis (2006) (0)
Assessment of Protein Allergenicity Following Systemic Exposure in Mice: Relationship with Immunogenicity (2009) (0)
REVIEW Toxicogenetics: Applications and Opportunities (2003) (0)
Bisphenol A, TH17 cells, and allergy: A commentary (2022) (0)
The XS106 cell line: profile of TLR ligand responses reveals a Langerhans cell-like phenotype (102.7) (2011) (0)
Relative frequencies of cytokine expressing CD4 and CD8 cells induced in mice by peanut allergen (2005) (0)
Contribution of interleukins 1a and 1 to langerhans cell migration (1998) (0)
Influence of vehicle upon potency estimation in the local lymph node assay: Further investigations (2000) (0)
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Functional dichotomy of dendritic cells isolated from blood and lymph nodes. (1995) (0)
In vitro alternatives: progress, challenges and opportunities (2018) (0)
Reprint of: Characterising hepatic mitochondrial function as a model for systemic toxicity: a commentary. (2012) (0)
Analysis of antigen-specific responses by high throughput sequencing of the T cell receptor repertoire (2016) (0)
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Use of lactoferrin in the treatment of complaints which are caused by allergens (1998) (0)
Respiratory Allergy : Hazard Identification and Risk Assessment 1 (0)
Honorary Doctorate awarded to Thomas Karger (1994) (0)
6.12 The evolutionary significance of natural killer cells (1989) (0)
Methlychloroisothiazolinone/methylisothiazolinone: A contact sensitizer or a respiratory allergen? (2013) (0)
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Cytokine gene expression following topical exposure of mice to chemical contact and respiratory allergens (1997) (0)
Chemical allergy: The relationships between in vitro tests, animal tests and clinical experience (2010) (0)
Acid anhydride activated murine Lymph Node Cells (LNC) produce interleukin (IL) 5 among other T helper cytokines (2000) (0)
331 Addition of interleukin-17 alters the healthy keratinocyte secretome and causes inhibition of Langerhans’ cell migration (2016) (0)
Characteristic cytoldne patterne induced by discrete classes of chemical altergen (1995) (0)
P051Changes in the level of expression and frequency of B220 positive lymphocytes may discriminate more accurately between contact allergens and skin irritants (2011) (0)
106 Cytokine profiling of chemical allergens: Inter-animal variation (2003) (0)
405 Topical administration of peanut lectin to mice stimulates specific antibody production (2000) (0)
Session 6: Mechanisms of allergic disease (2004) (0)
FORUM Toxicology of Protein Allergenicity: Prediction and Characterization (1999) (0)
Lacrimal lipocalin muteins and procedures for obtaining them. (2007) (0)
The aryl hydrocarbon receptor: Differential contribution to type 17 T cell subsets (2013) (0)
GENOMIC ANALYSES OF THE MOLECULAR BASES FOR TOXIC RESPONSES (2000) (0)
Professor Iain Francis Harvey Purchase (1937-2016) Founding Editor of Toxicology in Vitro (2016) (0)
Changes in gene expression profiles following topical exposure of mice to chemical respiratory allergen (2006) (0)
Interferon γ secretion and nitric oxide production by allergen-activated murine lymph node cells (1998) (0)
112 The induction of oral tolerance to ovalbumin in BALB/C strain mice (2003) (0)
Molecular basis of chemical allergy and novel approaches to sensitization testing (1998) (0)
Zenca Central Toxicoloty Laboratory (CTL) seminar, Alderley Park, Cheshire, UK, 26-27 January 1998: The scientific and practical basis for thresholds in biology (1998) (0)
Newer approaches to the evaluation of sensitization phenomena. (1994) (0)
The relationship between antibody concentration and target cell number in the induction of K cell-mediated haemolysis: evidence for asymmetry among reactants. (1983) (0)
Predictive Testing for Allergy: Critical evaluation (1997) (0)
Evaluation of the contact allergic potential of 2,4-dinitrothiocyanobenze (1996) (0)
Chemical respiratory allergen-induced gene expression profiles following topical exposure of mice (2006) (0)
Response (1998) (0)
Implementing 3Rs methods in toxicology: A view from academia (2015) (0)
Thioredoxin and lactoferrin differentially regulate Langerhans’ cell migration (102.4) (2011) (0)
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Innate defect? Bronchial epithelial cells of atopic patients with asthma lack the ability to activate allergens. (1996) (0)
Use of microarray expression profiling in PPARα null and wild-type mice to investigate the mechanism of hepatocarcinogenesis induced by the Peroxisome Proliferator diethylhexylphthalate (DEHP) (2000) (0)
INTERLEUKIN 5 EXPRESSION BY ALLERGEN-ACTIVATED MURINE LYMPH NODE CELLS (1999) (0)
91 How do natural and synthetic estrogens induce cell proliferation and differentiation? A transcriptional view of the uterotrophic response (2003) (0)
The Basics Immunological Aspects Direct interaction between antigen‐bearing dendritic cells and T‐lymphocytes during the induction phase of allergic contact dermatitis (1990) (0)
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Antigenic competition incontactsensitivity. Evidence forchanges indendritic cellmigration andantigen handling (1990) (0)
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299 Fibroblasts from aged human skin show an augmented pro-inflammatory response to TLR4 stimulation compared to young fibroblasts (2016) (0)
Endotoxin, IgE antibody responses and allergenicity assessment (2011) (0)
Regulation ofnatural andantibody-dependent cellular cytotoxicity bystaphylococcal enterotoxin A (1983) (0)
Differential antibody responses induced by Ara h 1 and patatin (2002) (0)
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Cytokines and the induction of contact sensitization (1995) (0)
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Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies (2019) (0)
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Recent Developments in Allergic Contact Dermatitis (2005) (0)
Acid anhydride-activated murine lymph node cells express interleukin 13 (2000) (0)
The Report and Recommendations of ECVAM Workshop 51 1,2 (2005) (0)
Pre- and postnatal sensitisation to foods. (2002) (0)
Differential Allergenicity of Human Lactoferrin: Role of Glycosylation (2008) (0)
Chemical insult and toll-like receptor ligands: Synergistic effects on dendritic cells (2007) (0)
Processes in Pathology: An Introduction for Students of Medicine (1980) (0)
Other manifestations of food intolerances. (2002) (0)
Identification of chemical sensitizers according to cytokine expression induced in draining lymph nodes (1996) (0)
Immunological Methods (1979) (0)
A response to Professor Steinemann. (2019) (0)
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6 Conclusions (2009) (0)
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Reduced allergy rates to contact allergens/haptens with both oral and cutaneous exposure in atopic eczema subjects. Atopy and the "hapten hypothesis" (2007) (0)
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News & Views (2007) (0)
Respiratory sensitisation: in the absence of an appropriate animal model how can an AoP approach help? (2018) (0)
Measurement of B220 expression: An adjunct to the standard local lymph node assay (LLNA)? (2011) (0)
Gene expression profiling in allergic contact dermatitis (2004) (0)
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The effect of extracellular matrix (ECM) on 2,4-dinitrochlorobenzene (DNCB)-induced responses of the dendritic cell surrogate THP-1 cells (2010) (0)
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CONTRIBUTION OF INTERLEUKIN 18 TO MURINE EPIDERMAL LANGERHANS CELL MIGRATION. (2000) (0)
Muteins of tearlipocalin and process for their recovery (2007) (0)
Changes in total serum IgE concentration in the brown Norway rat following topical exposure to respiratory and contact allergens (2000) (0)
Extended comparison of the local lymph node assay with guinea pig test methods (1998) (0)
Distinct cutaneous cytokine secretion profiles induced in mice by skin irritant and sensitising chemicals (2006) (0)
Contents, Vol. 103, 1994 (1994) (0)
Title Page / Table of Contents (2006) (0)
Specificity of the local lymph node assay (LLNA) for skin sensitisation. (2023) (0)
PD1-1 Measurement of Potency in Allergic Responses to Chemicals(PANEL DISCUSSION 1: RECENT STATUS AND FUTURE PERSPECTIVES OF IMMUNOTOXICOLOGY)(Proceedings of the 31st Annual Meeting) (2004) (0)
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1st Tatra Immunology Conference: Molecular Determinants of T Cell Immunity (1994) (0)
PL-2 Recent Advances in Chemical Allergy(SPECIAL LECTURE)(Proceedings of the 31st Annual Meeting) (2004) (0)
HLA and H-2. Basic Immunogenetics, Biology and Clinical Relevance. Current Topics in Immunology Vol. 9 (1979) (0)
Impact of environmental pollution on respiratory sensitization and asthma. (1996) (0)
3 Molecular basis and implications of functional subpopulations of T lymphocytes-the type 1/type 2 paradigm (2003) (0)
Handbook of Cancer Immunology, Vol. I: Basic Cancer-related Immunology (1979) (0)
141 Influence of 2,4-dinitrothiocyanobenzene on cutaneous dendritic cell migration (2000) (0)
Skin sensltization is associated with induced changes in cutansous cytokine expresion (1995) (0)
The immunological bases for protein immunogenicity and allergenicity (2014) (0)
A fresh look at T cells in psoriasis (2015) (0)
Enumeration of the frequency of Langerhans cells in epidermis: reply from authors (2002) (0)
Fibronectin feedback loops and their relationship with inflammatory skin diseases (48.11) (2010) (0)
Contact sensitisers induce CD 86 expression and apoptosis in an independent manner in U-937 cell line (2005) (0)
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Mechanism of skin sensitisation to 2,4-dinitrothiocyanobenzene (2000) (0)
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Use Of Microarray Expression Profiling To Investigate The Mechanism Of Hepatocarcinogenesis Induced By The Peroxisome Proliferator Diethylhexylphthalate (DEHP) In Mice (2000) (0)
Letter to the Editor (2010) (0)
Confocal Imaging of Low Affinity IgE Receptor Distribution on B cells: Effects of Grass Pollen Immunotherapy (2008) (0)
Allergen-induced langerhans’ cell migration: Requirement for tumour necrosis factor alpha (2014) (0)
Relationship between cell toxicity and interleukin (IL) 8 production for chemical contact allergens (2011) (0)
Session 19: Clinical immunology of psoriasis (2004) (0)
Topical exposure of mice to fluorescein isothiocyanate provokes a selective type 2 cvtokine secretion profile (1998) (0)
S12-5Enabling innovation and practical application of new and better science in toxicology (2016) (0)
P79 A chemical dataset for evaluation of alternative approaches to skin sensitization testing (2004) (0)
Analysis of interleukin 12 protein and mRNA expression following chronic exposure of mice to chemical allergens (1998) (0)
Contents, Vol. 97, 1992 (1992) (0)
Characterising hepatic mitochondrial function as a model for systemic toxicity: a commentary. (2012) (0)
Expression of the signalling receptor for interleukin 1 (IL-1RI) by murine epidermal Langerhans cells and keratinocytes (1997) (0)
Functional genomic analysis of stress-activated protein kinase signalling pathways (2003) (0)
Systemic exposure of mice to respiratory sensitizing pro teins: Induction of IgE* (2003) (0)
Mompha langiella (Hb.) (Lep: Momphidae): The first records for North Hampshire, VC12 (2003) (0)
The Application of Genomics and Proteomics to Toxicological Sciences (2003) (0)
IgE antibody responses induced in mice by protein allergens: Influence of bacterial endotoxin (2005) (0)
International Collaborative Studies on the Detection of Immunotoxicity (2013) (0)
Progress and needs for developing and validating alternatives for dermal sensitisation testing (2006) (0)
Investigating the factors that regulate the rate of intracellular IL-1β degradation (IRM12P.652) (2015) (0)
Inhalation exposure of sprague-dawley rats to methylene chloride (MeCl2) does not suppress humoral immune responses (2000) (0)
Changes in granzyme B gene expression induced by chemical allergens (2007) (0)
Allergenicity of human lactoferrin is dependent on glycosylation status (2007) (0)
Relationship between protein allergenicity and glycosylation (2009) (0)
Contact Sensitization in Mice Langerhans Cell Migration and Optimal Functional Caspase-1 Is Required for (2001) (0)
Differential function ofdendritic cells isolated frombloodandlymphnodes (1994) (0)
Joint meeting of the Experimental Contact Dermatitis Research Group and the American Contact Dermatitis Society in Baltimore, MD, September 28 to 30, 2006. (2007) (0)
Quantitative risk assessment for contact allergens: a simplified approach for hair dye ingredients (2013) (0)
Novel and integrated approaches to skin sensitisation testing (2007) (0)
The effect of sleep deprivation and exercise on reaction threshold in peanut-allergic adults: a randomised controlled study (2020) (0)
Book Reviews (1993) (0)
Interferon γ and nitric oxide production by allergen-activated murine lymph node cells (1998) (0)
Food Allergy: Immunological Aspects and Approaches to Safety Assessment (2006) (0)
Assessment of protein allergenic potential in mice: Inter-laboratory comparisons (2006) (0)
Allergic Contact Dermatitis to Chemicals: Immunological and Clinical Aspects (2006) (0)
Challenges in the classification of chemical respiratory allergens based on human data: Case studies of 2-hydroxyethylmethacrylate (HEMA) and 2-hydroxypropylmethacrylate (HPMA). (2023) (0)
Role of Lewis x sugars in the differential allergenicity of wild type and recombinant lactoferrin (2010) (0)
Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model (2022) (0)
Proteomics and AllerCatPro analysis for the identification of low allergenic proteins (2018) (0)
Molecular mechanisms associated with aberrant liver growth and carcinogenesis in F344 rats treated with phenobarbital (2006) (0)
Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects (2011) (0)
Predictive Tests for Irritants and Allergens: Human, Animal, and In Vitro Tests (2020) (0)
Chemical Allergy: Mechanisms, Clinical Experience, Animal Tests and In Vitro Tests (2011) (0)
Cytokine production by lymph node cells following antigen-induced unresponsiveness in mice (1997) (0)
REVIEW Assessing the Potential to Induce Respiratory Hypersensitivity (2006) (0)
Relationship between protein allergenicity and glycosylation (79.14) (2009) (0)
British Contact Dermatitis Society: Summaries of Papers (2008) (0)
Introduction: Allergy, asthma and the environment (1998) (0)
Cytokine expression by allergen-activated CD4+ and CD8+ cells (1997) (0)
The expression of VLA-4 and VLA-6 by langerhans cells - their potential role in regulating langerhans cell-migration[Abstract] (1995) (0)

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