Ian P. Hall
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Ian P. Hallcomputer-science Degrees
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Computer Science
Ian P. Hall's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Ian P. Hall's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction (2009) (790)
- Genome-wide association study identifies five loci associated with lung function (2010) (560)
- Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. (1995) (435)
- Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function (2011) (401)
- Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. (2005) (372)
- Association between β2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics (1997) (349)
- IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. (2013) (342)
- Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank (2015) (326)
- Association of Glu 27 β2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects (1995) (313)
- A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample (2011) (281)
- Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis (2017) (275)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. (2018) (257)
- Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms. (1994) (245)
- Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (2017) (217)
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell type and phenotype associations (2019) (200)
- Severe hyponatraemia in medical in-patients: aetiology, assessment and outcome. (2006) (198)
- Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. (2012) (187)
- A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea (2013) (180)
- Agonist and Inverse Agonist Actions of β-Blockers at the Human β2-Adrenoceptor Provide Evidence for Agonist-Directed Signaling (2003) (179)
- Haplotype estimation for biobank scale datasets (2016) (178)
- Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function (2012) (167)
- The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. (1997) (167)
- Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study (2017) (162)
- Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients. (1997) (153)
- Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells. (2001) (152)
- Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα (2012) (151)
- Thiazide diuretic prescription and electrolyte abnormalities in primary care. (2006) (148)
- Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. (2011) (144)
- Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study (2019) (141)
- Genome-wide association analysis identifies six new loci associated with forced vital capacity (2014) (141)
- A sequence variant on 17q21 is associated with age at onset and severity of asthma (2010) (137)
- Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis (2019) (133)
- The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol. (2003) (133)
- ORAI and store-operated calcium influx in human airway smooth muscle cells. (2008) (127)
- Effect of IL-1 beta on responses of cultured human airway smooth muscle cells to bronchodilator agonists. (1997) (122)
- Second messengers, ion channels and pharmacology of airway smooth muscle. (2000) (115)
- Contribution of ADAM33 polymorphisms to the population risk of asthma (2005) (113)
- Identification of novel polymorphisms within the promoter region of the human β2 adrenergic receptor gene (1999) (112)
- NMR Hyperpolarization Techniques of Gases. (2017) (111)
- alpha-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation. (1995) (111)
- Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (2015) (110)
- A key role for STIM1 in store operated calcium channel activation in airway smooth muscle (2006) (109)
- Association of CCR5 ▵32 with reduced risk of asthma (1999) (109)
- Impaired uptake of serotonin by platelets from patients with irritable bowel syndrome correlates with duodenal immune activation. (2011) (108)
- Cell adhesion and mechanical properties of a flexible scaffold for cardiac tissue engineering. (2007) (99)
- β2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study (2006) (98)
- Expression of transient receptor potential C6 and related transient receptor potential family members in human airway smooth muscle and lung tissue. (2004) (92)
- Implications of Genetic Variability of Human β2-adrenergic Receptor Structure (1995) (91)
- Expression of muscarinic M2 receptors in cultured human airway smooth muscle cells. (1993) (90)
- Inhibition of histamine‐stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle (1989) (90)
- Cyclic AMP-dependent Transcriptional Up-regulation of Phosphodiesterase 4D5 in Human Airway Smooth Muscle Cells (2002) (90)
- Carbachol-induced actin reorganization involves Gi activation of Rho in human airway smooth muscle cells. (1998) (89)
- Association of glutamine 27 polymorphism of β2 adrenoceptor with reported childhood asthma: population based study (1998) (86)
- β2 Agonists. (2017) (85)
- Agonist Actions of “β-Blockers” Provide Evidence for Two Agonist Activation Sites or Conformations of the Human β1-Adrenoceptor (2003) (85)
- Tryptase's potent mitogenic effects in human airway smooth muscle cells are via nonproteolytic actions. (2002) (84)
- Airway smooth muscle in bronchial tone, inflammation, and remodeling: basic knowledge to clinical relevance. (2008) (83)
- PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. (2009) (81)
- Efficacy of BI 671800, an oral CRTH2 antagonist, in poorly controlled asthma as sole controller and in the presence of inhaled corticosteroid treatment. (2015) (79)
- Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients. (1999) (78)
- Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma. (1998) (75)
- Meta-analysis of genome-wide linkage studies of asthma and related traits (2008) (75)
- Genetics and pulmonary medicine: asthma (1999) (72)
- Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
- Comparison of asthma treatment given in addition to inhaled corticosteroids on airway inflammation and responsiveness (2006) (72)
- Molecular mechanisms underlying variations in lung function: a systems genetics analysis. (2015) (71)
- Control of cyclic AMP levels in primary cultures of human tracheal smooth muscle cells (1992) (70)
- Use of cultured airway myocytes for study of airway smooth muscle. (1995) (70)
- Regulation of proliferation of human colonic subepithelial myofibroblasts by mediators important in intestinal inflammation. (1998) (70)
- Complications and mortality in hereditary hemorrhagic telangiectasia (2015) (68)
- Agonist and inverse agonist actions of beta-blockers at the human beta 2-adrenoceptor provide evidence for agonist-directed signaling. (2003) (68)
- Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol. (1998) (68)
- Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma. (2001) (66)
- The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study (2013) (65)
- A major functional role for phosphodiesterase 4D5 in human airway smooth muscle cells. (2008) (63)
- Isoenzyme selective phosphodiesterase inhibitors: potential clinical uses. (1993) (63)
- Variations in the subunit content and catalytic activity of the cytochrome c oxidase complex from different tissues and different cardiac compartments. (1998) (62)
- Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels (2013) (62)
- β2-Adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting β2-agonist therapy (1999) (62)
- Control of histamine induced inositol phospholipid hydrolysis in cultured human tracheal smooth muscle cells. (1993) (62)
- Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function (2014) (59)
- The selective CXCR2 antagonist SB272844 blocks interleukin-8 and growth-related oncogene-alpha-mediated inhibition of spontaneous neutrophil apoptosis. (2002) (58)
- Glucocorticoids Increase Repair Potential in a Novel in vitro Human Airway Epithelial Wounding Model (2006) (56)
- Association of CCR5 delta32 with reduced risk of asthma. (1999) (54)
- Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. (1999) (53)
- Pharmacogenetics of asthma. (2000) (53)
- Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia (2017) (52)
- Beta 2-adrenoceptor desensitization in cultured human airway smooth muscle. (1993) (52)
- Eosinophil-mediated cholinergic nerve remodeling. (2006) (51)
- Opportunities and Challenges in the Genetics of COPD 2010: An International COPD Genetics Conference Report (2011) (50)
- Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle. (2001) (50)
- Novel cAMP signalling paradigms: therapeutic implications for airway disease (2012) (50)
- Receptor Genotypes on Signal Transduction in Human Airway Smooth Muscle Cells (1995) (49)
- Molecular and phenotypic analyses of human embryonic stem cell-derived cardiomyocytes (2005) (48)
- Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses. (2003) (47)
- A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation? (2014) (46)
- Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
- β2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells (2002) (45)
- Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation (2010) (45)
- GSTCD and INTS12 Regulation and Expression in the Human Lung (2013) (44)
- Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma (2017) (44)
- Airway myofibroblasts and their relationship with airway myocytes and fibroblasts. (2008) (44)
- Beta 2 adrenoceptor polymorphisms: are they clinically important? (1996) (43)
- A biomechanical model of agonist-initiated contraction in the asthmatic airway (2010) (43)
- Genetic risk factors for the development of pulmonary disease identified by genome‐wide association (2018) (41)
- Epigenome-wide association study of lung function level and its change (2019) (41)
- Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome) (2013) (41)
- Pharmacogenetic approaches in the treatment of asthma (2005) (41)
- Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle. (2004) (40)
- Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells. (2010) (39)
- Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells. (2004) (39)
- Pharmacological characterization of CGP 12177 at the human β2‐adrenoceptor (2002) (39)
- Evidence for large-scale gene-by-smoking interaction effects on pulmonary function (2017) (38)
- Temporal characteristics of cAMP response element-mediated gene transcription: requirement for sustained cAMP production. (2004) (38)
- Modulation of human airway smooth muscle proliferation by type 3 phosphodiesterase inhibition. (1999) (38)
- Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke (2006) (37)
- 5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists (2002) (37)
- Investigating measurements of fine particle (PM2.5 ) emissions from the cooking of meals and mitigating exposure using a cooker hood. (2019) (35)
- Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts (2020) (35)
- Pharmacology and direct visualisation of BODIPY‐TMR‐CGP: a long‐acting fluorescent β2‐adrenoceptor agonist (2003) (34)
- A Genome‐Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos (2018) (34)
- Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction (2014) (34)
- Inositol phosphates and airway smooth muscle. (1989) (33)
- Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors. (1990) (33)
- Implications of genetic variability of human beta 2-adrenergic receptor structure. (1995) (33)
- Pharmacogenetics and asthma: false hope or new dawn? (2007) (32)
- Meta-analysis of exome array data identifies six novel genetic loci for lung function (2017) (31)
- Age at menarche and lung function: a Mendelian randomization study (2017) (31)
- Patient attitudes to clinical trials: development of a questionnaire and results from asthma and cancer patients (2005) (30)
- Are β2-adrenoceptor polymorphisms important in asthma—an unravelling story (2004) (30)
- A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom. (2011) (30)
- Abnormalities of mucosal serotonin metabolism and 5‐HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron (2019) (30)
- Refinement of welfare through development of a quantitative system for assessment of lifetime experience (2015) (30)
- Can crops be irrigated with sodium bicarbonate rich CBM deep aquifer water? Theoretical and field evaluation (2008) (29)
- Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells. (2007) (29)
- The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro (2016) (29)
- Effects of a range of β2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells (1999) (29)
- PLAUR polymorphisms and lung function in UK smokers (2009) (29)
- Genetic association studies in Thorax (2005) (29)
- Integrative pathway genomics of lung function and airflow obstruction. (2015) (28)
- Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium (2020) (28)
- Biosynthesized matrix provides a key role for survival signaling in bronchial epithelial cells. (2004) (26)
- Pharmacogenetics, pharmacogenomics and airway disease (2001) (26)
- Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12 (2016) (26)
- Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline (2017) (26)
- Genetically raised serum bilirubin levels and lung cancer: a cohort study and Mendelian randomisation using UK Biobank (2020) (25)
- Current progress in pharmacogenetics. (2011) (24)
- Human airway smooth muscle expresses 7 isoforms of adenylyl cyclase: a dominant role for isoform V. (2001) (24)
- The Role of Inflammation Resolution Speed in Airway Smooth Muscle Mass Accumulation in Asthma: Insight from a Theoretical Model (2014) (24)
- Alternative promoter use and splice variation in the human histamine H1 receptor gene. (2006) (22)
- Peripheral blood neutrophils are hyperresponsive to IL-8 and Gro-alpha in cryptogenic fibrosing alveolitis. (2001) (21)
- Improving communication between hospital and primary care increases follow-up rates for asthmatic patients following casualty attendance. (1998) (20)
- Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor. (2002) (20)
- Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy. (1999) (20)
- The β-agonist controversy revisited (2004) (20)
- Interleukin-1 β and Rhinovirus Sensitize Adenylyl Cyclase in Human Airway Smooth-Muscle Cells (2001) (20)
- HTR4 gene structure and altered expression in the developing lung (2013) (20)
- Phenotypic and functional translation of IL33 genetics in asthma. (2020) (19)
- Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) (2021) (19)
- Stratified medicine: drugs meet genetics (2013) (19)
- The future of asthma (1997) (17)
- Beta 2-adrenoceptor polymorphisms and asthma. (1996) (17)
- Copy Number Variation of the Beta-Defensin Genes in Europeans: No Supporting Evidence for Association with Lung Function, Chronic Obstructive Pulmonary Disease or Asthma (2014) (16)
- Identification of the autoantigen SART-1 as a candidate gene for the development of atopy. (2002) (16)
- The effect of β2‐adrenoceptor haplotypes on bronchial hyper‐responsiveness in patients with asthma (2006) (15)
- Interleukin-4 receptor alpha gene variants and allergic disease (2000) (15)
- Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr☆ (2014) (15)
- ADRB2 polymorphisms and β2 agonists (2007) (15)
- Setting the standard: The acceptability of kitchen ventilation for the English housing stock (2019) (15)
- The effect of β2-adrenoceptor agonists on phospholipase C (beta1) signalling in human airway smooth muscle cells (2006) (15)
- Agonist actions of "beta-blockers" provide evidence for two agonist activation sites or conformations of the human beta1-adrenoceptor. (2003) (15)
- Hypertension: β testing (2003) (14)
- Effect of high-dose salbutamol on cardiac rhythm in severe chronic airflow obstruction: a controlled study. (1994) (14)
- Reduced inflammatory responses to SARS-CoV-2 infection in children presenting to hospital with COVID-19 in China (2020) (14)
- Pharmacogenetics of asthma. (2000) (14)
- Agonist-induced inositol phosphate responses in bovine airway submucosal glands. (1992) (14)
- Associations of a novel IL4RA polymorphism, Ala57Thr, in Greenlander Inuit. (2006) (13)
- Personalised prescribing for asthma ‐ is pharmacogenetics the answer? (2003) (13)
- Salmeterol and cytokines modulate inositol-phosphate signalling in Human airway smooth muscle cells via regulation at the receptor locus (2007) (13)
- A data analysis of the Chilean housing stock and the development of modelling archetypes (2020) (13)
- Publishing genetic association studies in Thorax (2005) (13)
- New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries (2018) (12)
- Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development (2016) (12)
- Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways (2017) (12)
- Cyclic AMP and the Control of Airways Smooth Muscle Tone (1994) (12)
- Pharmacogenetics of asthma. (2006) (12)
- β 2 -Adrenoceptor Agonists (2009) (11)
- Interleukin-1beta and rhinovirus sensitize adenylyl cyclase in human airway smooth-muscle cells. (2001) (11)
- Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort. (2009) (11)
- Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways? (2010) (10)
- The genetics of obstructive lung disease: big is beautiful (2010) (10)
- Real time analysis of β2-adrenoceptor-mediated signaling kinetics in Human Primary Airway Smooth Muscle Cells reveals both ligand and dose dependent differences (2011) (10)
- Chloride intracellular channel 1 (CLIC1) contributes to modulation of cyclic AMP‐activated whole‐cell chloride currents in human bronchial epithelial cells (2018) (10)
- Effect of oral lithium on bronchial reactivity in asthma. (1992) (10)
- Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes (2007) (10)
- Beta-adrenoceptor stimulation inhibits histamine-stimulated inositol phospholipid hydrolysis in bovine tracheal smooth muscle. (1988) (10)
- Effects of a range of beta2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells. (1999) (10)
- A key role for STIM 1 in store operated calcium channel activation in airway smooth muscle (2006) (10)
- Cigarette Smoke and the Induction of Urokinase Plasminogen Activator Receptor In Vivo: Selective Contribution of Isoforms to Bronchial Epithelial Phenotype. (2014) (9)
- Effect of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone (1990) (9)
- Defining the inflammatory signature of human lung explant tissue in the presence and absence of glucocorticoid (2017) (9)
- Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease (2016) (9)
- Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone. (1992) (9)
- Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies (2011) (8)
- Developmental genetics of the COPD lung (2015) (8)
- Candidate gene studies in respiratory disease: avoiding the pitfalls (2002) (8)
- The beta-agonist controversy revisited. (2004) (8)
- Efficacy and safety of BI 671800, an oral CRTH2 antagonist, as add on therapy in poorly controlled asthma patients prescribed an inhaled corticosteroid (2012) (8)
- Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls (2017) (7)
- Hypertension: beta testing. (2003) (7)
- Genetic Associations and Architecture of Asthma-COPD Overlap (2022) (7)
- Fc(epsilon)RI-(beta) polymorphisms unlikely to contribute substantially to genetic risk of allergic disease (1996) (7)
- The effect of beta2-adrenoceptor agonists on phospholipase C (beta1) signalling in human airway smooth muscle cells. (2006) (7)
- Inhibition by salbutamol, forskolin and IBMX of AlF4-induced inositol phosphate formation in bovine airway smooth muscle. (1989) (6)
- Challenges of chronic obstructive pulmonary disease in rural Nepal. (2019) (6)
- The burden of chronic respiratory diseases in adults in Nepal: A systematic review (2021) (6)
- Expanded genetic landscape of chronic obstructive pulmonary disease reveals heterogeneous cell type and phenotype associations (2018) (6)
- Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank (2021) (6)
- A Systematic Analysis of Protein-altering Exonic Variants in Chronic Obstructive Pulmonary Disease. (2021) (5)
- ADRB2 polymorphisms and beta2 agonists. (2007) (5)
- Interleukin-4 receptor α gene variants and allergic disease (2000) (5)
- Agonist Action of “β-Blockers” Provide Evidence for Two Agonist Activation Sites on the Human β1-Adrenoceptor (2003) (5)
- Purulent pericarditis. (1989) (5)
- Modulation of human airway smooth muscle proliferation by type 3 phosphodiesterase inhibition. (1999) (5)
- Peripheral muscle training in COPD : still much to learn (2005) (5)
- Pro-Inflammatory Effects in ex vivo Human Lung Tissue of Respirable Smoke Extracts from Indoor Cooking in Nepal. (2020) (5)
- Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity (2014) (5)
- Association of the Gln 27 beta 2-adrenoceptor polymorphism and IgE variability in asthmatic families. (1997) (5)
- Altitude induced illness. (1992) (4)
- Defining a role for lung function associated gene GSTCD in cell homeostasis (2019) (4)
- Functional genomics of GPR126 in airway smooth muscle and bronchial epithelial cells (2021) (4)
- How will genetic approaches assist in the management of respiratory diseases? (2009) (4)
- Purinergic Receptors in the Airways: Potential Therapeutic Targets for Asthma? (2021) (4)
- Effects of atopy and grass pollen season on histamine H₄ receptor expression in human leukocytes. (2013) (4)
- Pharmacogenetics and ethnicity: more complexities of personalized prescribing. (2005) (4)
- University of Groningen Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha 1-antitrypsin Serum Levels (2013) (4)
- A Simple Asthma Severity Score Predicts Exacerbations (2011) (4)
- Audit of a complete home nebulizer service provided by a respiratory nurse specialist. (1994) (4)
- Interstitial lung damage following COVID-19 hospitalisation: an interim analysis of the UKILD Post-COVID study. (2022) (3)
- Digestive Tract Disorders (1998) (3)
- Single nucleotide polymorphism analysis of the human adenosine A2B receptor gene: Prevalence of SNPs in asthmatics and normal subjects (2002) (3)
- Variants associated with HHIP expression have sex-differential effects on lung function. (2020) (3)
- CHAARM: A model to predict uncertainties in indoor pollutant concentrations, ventilation and infiltration rates, and associated energy demand in Chilean houses (2021) (3)
- Association of Proinflammatory Genetic Polymorphisms With the Irritable Bowel Syndrome (IBS): Phenotype and Genotype Correlation (2011) (3)
- A weighted genetic risk score based on 279 signals of association with lung function predicts Chronic Obstructive Pulmonary Disease (2018) (3)
- Does use or withdrawal of long-acting β2-adrenoceptor induce desensitisation? (1998) (3)
- Frontispiece: NMR Hyperpolarization Techniques of Gases (2017) (3)
- Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study (2022) (3)
- Genetic polymorphisms of adrenergic receptors. (2000) (3)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (3)
- FLT1: a potential therapeutic target in sepsis-associated ARDS? (2020) (2)
- The genetics of asthma. Candidate gene approaches: gene-environmental interactions. (1998) (2)
- ß-Adrenoceptor Agonists (1998) (2)
- A Genome Wide Association Study of Moderate-Severe Asthma in subjects from the United Kingdom (2017) (2)
- Genome-Wide Association Study To Identify Genetic Determinants Of Severe Asthma (AUGOSA) (2011) (2)
- Assessing the impact of posture on diaphragm morphology and function using an open upright MRI system-A pilot study. (2020) (2)
- Real Time Analysis Of The Initiation And Rate Of Beta2-Adrenoceptor-Mediated Response In Human Primary Airway Smooth Muscle Cells Reveals Both Ligand And Dose Dependent Differences (2011) (2)
- Genetics of asthma. (1999) (2)
- Edinburgh Research Explorer Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry (2017) (2)
- The Development of Archetypes to Represent the Chilean Housing Stock (2017) (2)
- Association study between asthma and single nucleotide polymorphisms of ORMDL3, GSDMB, and IL1RL1 genes in an Algerian population (2021) (2)
- Conference scene: UK pharmacogenetics and stratified medicine network. (2012) (2)
- 680 Elevated Chemokine mRNA in Rectal Mucosa Following Gastrointestinal Infection and in Irritable Bowel Syndrome (2009) (2)
- Genetics of asthma and atopy (1996) (2)
- CLINICAL PHARMACY TEACHING FOR UNDERGRADUATES (1997) (2)
- Real Time Confocal Imaging And FRET-based Studies Of Dynamic Stim1 And Orai Interactions in Human Airway Smooth Muscle Cells During Store-Operated Calcium Influx (2010) (2)
- Should we use ADRB2 variation to stratify asthma treatment? (2014) (2)
- Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction (2012) (2)
- Mechanisms of Action of β2 Adrenoceptor Agonists (2009) (2)
- Pleiotropic effects of heterozygosity for the SERPINA1 Z allele in the UK Biobank (2020) (2)
- Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk (2023) (2)
- An intervention study of PM2.5 concentrations measured in domestic kitchens (2018) (2)
- Lack of Association of Functional Interleukin-6 and Interleukin-10 Polymorphisms with Idiopathic Pulmonary Fibrosis (2001) (1)
- Agonist-specific Temporal Characteristics of β2-Adrenoceptor-Stimulated Gene Transcription Response in CHO-K1 Cells Transfected with the Human β2-Adrenoceptor (2002) (1)
- Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice (2019) (1)
- SERIES "THE AIRWAY SMOOTH MUSCLE CELL" Edited by F. Chung and P. Sterk Number 4 in this Series Second messengers, ion channels and pharmacology of airway smooth muscle (2000) (1)
- Susceptibility Loci Regulating Total Serum IgE Levels , Bronchial Hyperresponsiveness , and Clinical Asthma Map to Chromosome 5 q * (1)
- Serum urate and lung cancer: a cohort study and Mendelian randomization using UK Biobank (2021) (1)
- Early experience of oxygen enhanced magnetic resonance imaging (OE-MRI) in ataxia telangiectasia (A-T) (2018) (1)
- Airways Smooth Muscle Cells in Culture (1994) (1)
- Azithromycin for treatment of bronchiolitis obliterans syndrome in adult lung transplant recipients (2017) (1)
- Use of FEV1 as a measure of lung health in the UK BiLEVE study - Authors' reply. (2015) (1)
- Mechanisms Underlying Ca 2+ Store Refilling in Airway Smooth Muscle (2014) (1)
- New Loci Associated with Lung Function and Chronic Obstructive Pulmonary Disease (2010) (1)
- Discussion Session A: The early life origins of asthma (1998) (1)
- The Uk Bileve Study: The First Genetic Study In Uk Biobank Identifies Novel Regions Associated With Airway Obstruction And Smoking Behaviour (2015) (1)
- Novel Thoracic MRI Approaches for the Assessment of Pulmonary Physiology and Inflammation. (2021) (1)
- Thoracic Surgical Procedures (1998) (1)
- A genome-wide association study of asthma-COPD overlap syndrome (ACOS) (2020) (1)
- Key topics in respiratory medicine (1998) (1)
- University of Groningen Genome-wide association studies identify CHRNA 5 / 3 and HTR 4 in the development of airflow obstruction (2017) (1)
- Cover Picture: NMR Hyperpolarization Techniques of Gases (Chem. Eur. J. 4/2017) (2017) (1)
- Reproducibility of hyperpolarised xenon-129 MRI (129Xe-MRI) of lungs in healthy volunteers (2017) (1)
- Pharmacogenetics: focus on pharmacodynamics (2001) (1)
- The Role Of Receptor For Advanced Glycation Endproducts (RAGE) And 5-Hydroxytryptamine Receptor Subtype 4 (5HTR4) In Bronchial Epithelial Function (2012) (1)
- Drug-Induced Lung Disease (1998) (1)
- Modelling Virus-Host Interactions: TLR-Induced Release of Inflammatory Mediators in Human Lung Explants (2019) (1)
- in MOCS 3 , IFIT 3 and SERPINA 12 (2016) (1)
- Genome-Wide Association Study to Identify Genetic Determinants of Atopy (2010) (1)
- Asthma genetics 2014: reaching for high‐hanging fruit (2014) (1)
- Prevalence of Atopy/Asthma Associated Alleles in 7 Different Populations (2003) (1)
- Genome-wide association and large scale follow-up identifies 16 novel loci for lung function (2011) (1)
- CO-CONNECT: A hybrid architecture to facilitate rapid discovery and access to UK wide data in the response to the COVID-19 pandemic. (2022) (1)
- Genome-wide association study of susceptibility to hospitalised respiratory infections (2021) (1)
- Mendelian randomisation analyses of eosinophils and other blood cell types in relation to lung function and disease. (2020) (1)
- Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease (2022) (1)
- Variants associated with HHIP expression have sex-differential effects on lung function (2021) (1)
- Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function (2021) (1)
- Multi-ancestry genetic risk score for lung function from meta-analysis of genome-wide association studies in 580,869 individuals from five ancestry groups (2022) (1)
- BREATHE: The Health Data Research Hub for Respiratory Health. (2022) (1)
- Genome-wide association study of susceptibility to hospitalised respiratory infections [version 1; peer review: awaiting peer review] (2021) (1)
- PCSK6 and Survival in Idiopathic Pulmonary Fibrosis (2022) (1)
- Patient-related outcomes in patients referred to a respiratory clinic with persisting symptoms following non-hospitalised COVID-19 (2022) (1)
- Domesticating cleaner cookstoves for improved respiratory health: Using approaches from the sanitation sector to explore the adoption and sustained use of improved cooking technologies in Nepal. (2022) (1)
- The effect of enhanced stove design on ‘real life’ exposure to PM 2.5 and CO in rural dwellings in Salambu, Nepal (2017) (1)
- Unusual Respiratory Infections (1998) (0)
- Household air pollution (HAP) from solid biomass fuel and lung inflammation: An exposure study in rural high altitude households of Nepal. (2020) (0)
- Lack of Association between IL-13 Pathway Gene Polymorphisms and COPD Susceptibility in UK Smokers. (2009) (0)
- Systems Genetics Approach Identifies Nicotine Receptor Antagonist As A Potential Therapeutic Target In COPD (2015) (0)
- Comprehensive Evaluation Of Mild-To-Moderate Asthma Genes In Severe Asthma (augosa) (2011) (0)
- Genome-Wide Association Study Identifies Novel Loci Associated With Reversibility To ²2 Agonist In Severe Asthma Subjects (2012) (0)
- Carbachol-induced actin reorganization involves Gi activation of Rho in human airway smooth muscle cells. (1998) (0)
- NPNT Knock Down Leads to Reveal Function in Human Bronchial Epithelial Cells (2019) (0)
- Association of the arginine-16 polymorphism desensitization and β2-agonist intrinsic efficacy (2003) (0)
- Pharmacogenetics of Respiratory Disease (2016) (0)
- ES8 Asthma and beta2 agonists (2012) (0)
- NMR Spectroscopy NMR Hyperpolarization Techniques of Gases (2017) (0)
- Developmental Disorders and Mediastinal Disease (1998) (0)
- Identification of a novel regulatory mechanism for the disease associated protein, uPAR (2014) (0)
- AUTHORS' REPLY (1996) (0)
- P109 Regional assessment of lung function using non-contrast MRI in people with cystic fibrosis (2021) (0)
- Activation Of Store-Operated Cation Channels Involves STIM-1 And Orai-1 In Cultured Human Airway Smooth Muscle (HASM) Cells (2012) (0)
- IL33 receptor activation is IL33 isoform and receptor genotype specific (2019) (0)
- Genetic and Molecular Regulation of β 2 -Adrenergic Receptors (2009) (0)
- Re-sequencing of PLAUR in severe asthma patients identifies novel variation (2014) (0)
- Expression Profiling of Splice Variants of the Histamine H 4 Receptor in Human Airways and Periphery. (2009) (0)
- Genome-wide association analysis identifies six new loci associated with forced vital capacity | NOVA. The University of Newcastle's Digital Repository (2014) (0)
- Profiling the Expression of Histamine H4 Receptor Isoforms in Human Airways and Periphery (2010) (0)
- Unifying the UK’S Data for Respiratory Science: BREATHE, The Health Data Research UK (HDR UK) Respiratory Health Data Research Hub (2020) (0)
- A Genome-Wide Association Study of > 250,000 Subjects Identifies Novel Risk Loci for COPD (2018) (0)
- IL11 Understanding lung function and asthma : does Genetics help? (2012) (0)
- Edwin K. Silverman, Steven D. Shapiro, David A. Lomas, Scott T. Weiss: Respiratory Genetics (2007) (0)
- Editorial: understanding differences in patient response to ondansetron in irritable bowel syndrome with diarrhoea—are we any closer? Authors' reply (2019) (0)
- Using transcriptomics to understand the potential functions of lung function associated gene, GPR126 in human airway smooth muscle cells (2019) (0)
- Asthma exacerbations and eosinophilia in the UK Biobank: a Genome-Wide Association Study (2022) (0)
- human adenosine A 2B receptor gene: prevalence (2002) (0)
- on in the Human Lung (2013) (0)
- smooth muscle cells are via nonproteolytic actions Tryptase's potent mitogenic effects in human airway (2016) (0)
- Association of glutamine 27 polymorphism of beta2 adrenoceptor childhood with reported asthma is age-dependent (2000) (0)
- Phosphodiesterase 4D5 Expression in Human Airway Smooth Muscle Cells is Controlled by Cyclic AMP (2003) (0)
- GWAS Identifies That A Human Plasma Kallikrein Single Nucleotide Polymorphism Regulates Serum PLAUR Levels In Asthma And COPD (2012) (0)
- Faculty Opinions recommendation of Orai proteins interact with TRPC channels and confer responsiveness to store depletion. (2007) (0)
- Secretory Profile of Human Bronchial Epithelial Cell (HBEC) In Vitro Post-Injury. (2009) (0)
- Expression profiling: fishing and chips (2004) (0)
- Inflammatory Effects of Short-Term Exposure to Smoke Emissions from Biomass Fuels (2018) (0)
- The role of ALOX5AP, LTA4H and LTB4R polymorphisms in COPD, atopy and asthma (2009) (0)
- Hyperpolarised xenon-129 MRI (129Xe-MRI) of lung in healthy adult volunteers (2016) (0)
- Chronic lung diseases--Institut Pasteur Euroconference. (2001) (0)
- Practical phenotyping of dif fi cult asthma (2014) (0)
- Approach to Unravel the Molecular Mechanisms Underlying Variations in Lung Function (2015) (0)
- Chapter 49 – β2-Adrenoceptor Agonists (2002) (0)
- Obeidat et al. 2013 PLoS ONE (2015) (0)
- EMISSIONS FROM THE COOKING OF MEALS AND MITIGATING (2019) (0)
- Gene Expression Profiling of Mesenchyme-Derived Cell Population in Human Airways. (2009) (0)
- Commentary Interleukin-4 receptor α gene variants and allergic disease (2000) (0)
- Natriuretic peptides and asthma: is there a connection? (2008) (0)
- /1-Adrenoceptor stimulation inhibits histamine-stimulated inositol phospholipid hydrolysis in bovine tracheal smooth muscle (2006) (0)
- Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways (2017) (0)
- Practical phenotpying of difficult asthma (2014) (0)
- Re-sequencing of IL33 and IL1RL1 in severe asthma patients identifies novel variation (2014) (0)
- Genome-Wide Interaction Study With Cigarette Smoking In Relation To Pulmonary Function (2011) (0)
- Genetics of COPD (2014) (0)
- Report of the Working Group on functional genetics/molecular approaches to asthma genetics (1998) (0)
- Meta-Analysis Of Genome-Wide Association Studies Of Longitudinal Decline In Lung Function (2012) (0)
- Identification of novel alternative lung function gene transcripts using high-throughput mRNA sequencing (2014) (0)
- Implicating biological pathways in lung function and COPD by variant-to-gene mapping of novel signals from a multi-ancestry meta-analysis of genome-wide association studies (2022) (0)
- Mutation Screening of the Histamine H4Receptor Coding Region and Validation of Single Nucleotide Polymorphisms. (2009) (0)
- Haplotype estimation for biobank scale datasets 1 2 (2016) (0)
- INTS12knockdown leads to perturbation of genes and pathways of relevance to airway biology (2015) (0)
- Epigenome-wide association study of lung function level and its change. European Respiratory Journal. (2019) (0)
- Multi-Combination Driver Training and Assessment (2018) (0)
- Evaluation of outpatient treatment for non-hospitalised patients with COVID-19: The experience of a regional centre in the UK (2023) (0)
- The Inflammatory Profile of Human Lung Explant Tissue in Response to Smoke Exposure from Biomass Burning (2019) (0)
- Genetic and environmental factors linked with oxidant-antioxidant balance and their relationship with respiratory health in UK Biobank (2019) (0)
- Polygenic Risk Scores in Chronic Obstructive Pulmonary Disease and Related Phenotypes (2020) (0)
- Functional Translation of IL33 Locus Polymorphisms Into Altered Epithelial Cell Function Underlying Asthma (2019) (0)
- A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study (2022) (0)
- HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW Systematic Review and Meta-Analysis of the Association between b 2 -Adrenoceptor Polymorphisms and Asthma: A HuGE Review (2005) (0)
- Determining the contribution of IL33 and IL1RL1 polymorphisms to clinical and immunological features of asthma (2016) (0)
- Prevalence of Klhl3 and Cul3 Mutations in Familial Hyperkalemic Hypertension (2014) (0)
- Patient Attitudes toward Clinical Trials Questionnaire (2017) (0)
- ASH XIII abstractβ2 adrenoceptor polymorphism and vascular reactivity in human resistance and capacitance vessels (1998) (0)
- Proton MRI assessment of lung structure and function in people with cystic fibrosis (2021) (0)
- Cigarette Smoke Modulates PLAUR Expression In Bronchial Epithelial Cells Via A 3`UTR Mechanism (2012) (0)
- Ninety seven independent genomic signals for lung function predict susceptibility to moderate to severe COPD (2016) (0)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Practical phenotyping of difficult asthma (2013) (0)
- Respiratory research in the UK: investing for the next 10 years (2022) (0)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- IL33 and TNFα synergistically enhance store operated Ca2+ entry in cultured human airway smooth muscle cells (2013) (0)
- Methods for Determining β(2)-Adrenoreceptor Genotype. (2000) (0)
- Expression Of Histamine H4 Receptor Isoforms In Peripheral Leukocytes Isolated From The Whole Blood Of Non-Atopic And Atopic Volunteers During Low And High Grass Pollen Seasons (2011) (0)
- S83 Genetically raised serum urate and lung cancer: a cohort study and mendelian randomisation using UK Biobank (2021) (0)
- Extracellular matrix protein promotes survival of human colonic sub-epithelial myofibroblasts by beta1-integrin dependent inhibition of apoptosis (1998) (0)
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (2019) (0)
- P1392Outcomes of out of hospital cardiac arrest patients who undergo primary percutaneous coronary intervention (2017) (0)
- Late Breaking Abstract - Reported outcomes in patients referred with persisting respiratory symptoms following non-hospitalised COVID-19 (2021) (0)
- Transcriptional Regulation of Phosphodiesterase 4D Splice Variant 5 (PDE4D5) in Human Airway Smooth Muscle (2002) (0)
- Muscle volume, functionality and metabolic resilience during recovery following severe COVID-19 (2022) (0)
- Audit of lipid modification therapy in patients with acute coronary syndrome (2014) (0)
- Type 2 Cytokines and Biomarkers in Asthma Patient Sera Show Coordinated Expression and Identify Patient Subsets (2019) (0)
- Respiratory morbidity in Nepali communities: a cross-sectional analysis (2021) (0)
- A Stochastic Approach to Estimate Uncertainty in Pollutant Concentrations in an Archetypal Chilean House (2018) (0)
- Re-Sequencing To Identify Rare Variants Within IL1RL1 And IL33 Genes In Severe Asthma And Control Subjects (2012) (0)
- Polymorphisms in UPAR Are COPD Susceptibility Markers and Predict COPD and Asthma Severity. (2009) (0)
- Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and airway epithelium in asthma (2018) (0)
- Drug Treatment of Airways Obstruction — New Questions about Old Drugs (1990) (0)
- Lung Function Tests (1998) (0)
- Shared polygenic effects of FEV1 in the first genetic study in UK Biobank (2015) (0)
- Investigating Soluble Cleaved Upar As A Biomarker For COPD (2011) (0)
- Genome-Wide Association Study Identifies Novel Loci Associated With Forced Expiratory Volume In One Second (FEV1) As A Percent Of Predicted In Severe Asthma Subjects (2012) (0)
- Pharmacogenetics, pharmacogenomics and gene therapy (2004) (0)
- Downregulation of TRPC6 expression by pro-inflammatory cytokines in cultured human airway smooth muscle cells (2005) (0)
- Profiling of COPD and IPF Cytokine Responses in Human Lung (2020) (0)
- Joint Effect of Single-Nucleotide Polymorphisms and Smoking Exposure in Chronic Obstructive Pulmonary Disease Risk (2012) (0)
- Genome Wide Association Study To Identify SNPs Regulating IL33 And SIL1RL1 Serum Levels In Asthma (2012) (0)
- BRONCHODILATORS | Beta Agonists (2006) (0)
- Using an upright MRI system to assess the impact of posture on diaphragm morphology (2019) (0)
- Desensitization of Histamine H1-Receptor-Mediated Calcium Responses in Human Umbilical Vein Endothelial-Cells (1995) (0)
- Promoter Mapping And Expression Profiling Of GSTCD/INTS12 Locus At 4q21 Recently Associated With Lung Function Measures In The General Population (2012) (0)
- Fine Mapping of Atopy Loci on Chromosomes 3 and 17. (2009) (0)
- Assessing the validity of genetic association studies. Author's reply (2005) (0)
- The effects of INTS12 knockdown on processing of snRNAs (2014) (0)
- L3 Structural and functional proton MRI assessment of cystic fibrosis lung disease in people with F508-del mutation (2021) (0)
- IS1-3 Airway smooth muscle : a key player in Asthma(Key cells in allergic diseases) (2012) (0)
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