Ian R. Hart
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Biology
Ian R. Hart's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Ian R. Hart's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Metastatic potential correlates with enzymatic degradation of basement membrane collagen (1980) (1829)
- Biological diversity in metastatic neoplasms: origins and implications. (1982) (975)
- The biology of cancer invasion and metastasis. (1978) (606)
- Metastatic behavior of human tumor cell lines grown in the nude mouse. (1984) (463)
- Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors (2009) (445)
- A line of non‐tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth (1987) (441)
- Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. (1980) (433)
- In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. (1980) (432)
- The selection and characterization of an invasive variant of the B16 melanoma. (1979) (375)
- Biology of tumour metastasis (1992) (315)
- Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression. (2011) (312)
- E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. (1993) (306)
- Stromal features are predictive of disease mortality in oral cancer patients (2011) (284)
- A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. (1984) (246)
- Multiple ways of silencing E‐cadherin gene expression in lobular carcinoma of the breast (2001) (224)
- A direct role for Met endocytosis in tumorigenesis (2011) (217)
- Molecular aspects of the metastatic cascade. (1989) (203)
- Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. (1991) (195)
- Mechanisms of tumour metastasis. (1998) (194)
- The implications of tumor heterogeneity for studies on the biology and therapy of cancer metastasis (1981) (192)
- Inhibitors of nitric oxide synthase selectively reduce flow in tumour‐associated neovasculature (1992) (189)
- The intracellular hyaluronan receptor RHAMM/IHABP interacts with microtubules and actin filaments. (1999) (186)
- Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential. (1985) (171)
- Early onset of breast cancer in a group of British black women (2008) (164)
- Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth. (1981) (162)
- ‘Seed and soil’ revisited: mechanisms of site-specific metastasis (2004) (154)
- Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. (1995) (138)
- Cell surface properties of B16 melanoma variants with differing metastatic potential. (1980) (136)
- αvβ6integrin promotes invasion of squamous carcinoma cells through up‐regulation of matrix metalloproteinase‐9 (2001) (134)
- Matrix metalloproteinases and metastatic cancer. (1998) (131)
- Effect of sulfonation on the cell and tissue distribution of the photosensitizer aluminum phthalocyanine. (1990) (130)
- Cell uptake, distribution and response to aluminium chloro sulphonated phthalocyanine, a potential anti-tumour photosensitizer. (1986) (129)
- Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16 (1997) (129)
- Site-Directed Perturbation of Protein Kinase C- Integrin Interaction Blocks Carcinoma Cell Chemotaxis (2002) (127)
- Integrin trafficking and its role in cancer metastasis (2007) (124)
- Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells. (2009) (123)
- Expression of the αvβ6 Integrin Promotes Migration and Invasion in Squamous Carcinoma Cells (2001) (123)
- The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells. (1998) (117)
- HS1-Associated Protein X-1 Regulates Carcinoma Cell Migration and Invasion via Clathrin-Mediated Endocytosis of Integrin αvβ6 (2007) (117)
- The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development (2007) (117)
- Tissue uptake, distribution, and potency of the photoactivatable dye chloroaluminum sulfonated phthalocyanine in mice bearing transplantable tumors. (1988) (112)
- Metastasis and angiogenesis. (1990) (111)
- Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown. (1990) (107)
- Therapeutic Targeting of Integrin αvβ6 in Breast Cancer (2014) (107)
- Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability (2003) (101)
- Follow-up of solitary autonomous thyroid nodules treated with 131I. (1983) (101)
- Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence (2013) (95)
- Integrin expression in human melanoma cell lines: Heterogeneity of vitronectin receptor composition and function (1991) (94)
- An in vitro quantitative assay for tumor cell invasion. (1978) (92)
- The origin of metastatic heterogeneity in tumors. (1981) (91)
- The role of αv-integrins in tumour progression and metastasis (1996) (90)
- αvβ6 Integrin Upregulates Matrix Metalloproteinase 9 and Promotes Migration of Normal Oral Keratinocytes (2001) (90)
- Betel‐derived alkaloid up‐regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis (2011) (90)
- Influence of tumor-derived interleukin 1 on melanoma-endothelial cell interactions in vitro. (1991) (87)
- Tumour angiogenesis is reduced in the Tc1 mouse model of Down Syndrome (2010) (86)
- Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes (2016) (86)
- alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice. (2008) (85)
- Expression of alphav integrins and vitronectin receptor identity in breast cancer cells. (1998) (85)
- Proliferating cell nuclear antigen expression in non-cycling cells may be induced by growth factors in vivo. (1994) (85)
- Biological and experimental consequences of the zonal composition of solid tumors. (1981) (85)
- Characterization of a murine ovarian reticulum cell sarcoma of histiocytic origin. (1981) (81)
- Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes (2003) (80)
- Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides (2002) (80)
- Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome. (2008) (79)
- Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer (2003) (79)
- Increased experimental metastatic capacity of a murine melanoma following induction of differentiation. (1986) (77)
- Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression. (1996) (72)
- HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. (2007) (72)
- AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9. (2001) (72)
- The Integrins α3β1and α6β1Physically and Functionally Associate with CD36 in Human Melanoma Cells: REQUIREMENT FOR THE EXTRACELLULAR DOMAIN OF CD36 (2000) (71)
- The pattern of expression of the microtubule‐binding protein RHAMM/IHABP in mammary carcinoma suggests a role in the invasive behaviour of tumour cells (2001) (71)
- Murine melanoma: a model for intracranial metastasis. (1980) (70)
- In Vivo Retargeting of Adenovirus Type 5 to αvβ6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery (2009) (70)
- alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. (2008) (70)
- Endothelial FAK is required for tumour angiogenesis (2010) (70)
- Functional interaction between E-cadherin and alphav-containing integrins in carcinoma cells. (2000) (69)
- Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability. (1998) (69)
- Enhanced experimental metastatic capacity of a human tumor line following treatment with 5-azacytidine. (1986) (68)
- Foot-and-Mouth Disease Virus Forms a Highly Stable, EDTA-Resistant Complex with Its Principal Receptor, Integrin αvβ6: Implications for Infectiousness (2007) (66)
- Factors influencing blood supply in wound granuloma quantitated by a new in vivo technique. (1989) (66)
- Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells. (1980) (66)
- Corrigendum: Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes (2016) (65)
- Cell adhesion receptor expression during melanoma progression and metastasis (1991) (64)
- Structure-Function Analysis of Arg-Gly-Asp Helix Motifs in αvβ6 Integrin Ligands* (2007) (64)
- Patients with recessive dystrophic epidermolysis bullosa develop squamous-cell carcinoma regardless of type VII collagen expression. (2007) (62)
- Cyclooxygenase-2 Inhibition Suppresses αvβ6 Integrin–Dependent Oral Squamous Carcinoma Invasion (2006) (61)
- Alpha v beta 1 is a receptor for vitronectin and fibrinogen, and acts with alpha 5 beta 1 to mediate spreading on fibronectin. (1995) (59)
- Reduction of TSG101 protein has a negative impact on tumor cell growth (2004) (59)
- Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by αvβ1 integrin and can be modulated by changes in β1 integrin function (2001) (58)
- Desmoglein 3, via an Interaction with E-cadherin, Is Associated with Activation of Src (2010) (58)
- Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. (2010) (58)
- The Integrin Cytoplasmic-tail Motif EKQKVDLSTDC Is Sufficient to Promote Tumor Cell Invasion Mediated by Matrix Metalloproteinase (MMP)-2 or MMP-9* (2004) (57)
- Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth. (1991) (57)
- Ezrin interacts with cortactin to form podosomal rosettes in pancreatic cancer cells (2008) (57)
- Ability to acquire drug resistance arises early during the tumorigenesis process. (2007) (55)
- Isolation and preliminary characterization of an Adriamycin-resistant murine fibrosarcoma cell line. (1983) (55)
- Non‐junctional human desmoglein 3 acts as an upstream regulator of Src in E‐cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris (2012) (53)
- Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome (2010) (53)
- Endothelial FAK is required for tumour angiogenesis (2016) (53)
- Induction of tumorigenicity and lack of in vitro growth requirement for 12-O-tetradecanoylphorbol-13-acetate by transfection of murine melanocytes with v-Ha-ras. (1989) (52)
- High‐resolution in vivo imaging of breast cancer by targeting the pro‐invasive integrin αvβ6 (2010) (51)
- Mechanisms of metastasis. (1997) (51)
- Photocytotoxic efficacy of sulphonated species of aluminium phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumours. (1991) (49)
- Investigation of alternative prodrugs for use with E. coli nitroreductase in 'suicide gene' approaches to cancer therapy. (1996) (49)
- Comparison of the effects of thyrotropin and the long-acting thyroid stimulator on guinea pig adipose tissue. (1971) (49)
- alpha v beta 6 Integrin upregulates matrix metalloproteinase 9 and promotes migration of normal oral keratinocytes. (2001) (48)
- Proteome of formalin‐fixed paraffin‐embedded pancreatic ductal adenocarcinoma and lymph node metastases (2012) (48)
- Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells. (2001) (48)
- The integrins alpha3beta1 and alpha6beta1 physically and functionally associate with CD36 in human melanoma cells. Requirement for the extracellular domain OF CD36. (2000) (45)
- Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference. (2007) (45)
- The effect of magnetic susceptibility variations in NMR imaging and nmr spectroscopy in vivo (1986) (44)
- FAK-heterozygous mice display enhanced tumour angiogenesis (2013) (44)
- Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell‐surface marker of the basal phenotype that promotes tumour cell invasion (2011) (43)
- Tissue specific promoters in targeting systemically delivered gene therapy. (1996) (43)
- The role of alpha v-integrins in tumour progression and metastasis. (1996) (42)
- Cancer Invasion and Metastasis (1980) (42)
- Metalloproteinase domain structure, cellular invasion and metastasis. (1994) (41)
- Immunotherapy: Fusion induces tumour rejection (1997) (40)
- PHOTODYNAMIC THERAPY OF A MURINE TUMOR FOLLOWING SENSITISATION WITH CHLORO ALUMINUM SULFONATED PHTHALOCYANINE (1987) (39)
- Selective delivery of drugs encapsulated in liposomes: natural targeting to macrophages involved in various disease states. (1983) (39)
- Loss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation. (2009) (39)
- Growth of melanocytic cells is associated with down-regulation of protein kinase C alpha, delta, and epsilon isoforms. Possible role of diacylglycerol. (1993) (39)
- Problems with RHAMM A New Link between Surface Adhesion and Oncogenesis? (1998) (39)
- Demonstration of histamine H2 receptors on human melanoma cells. (1988) (38)
- Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. (2006) (38)
- CD44 and its role in tumour progression and metastasis. (1993) (38)
- Correlation of tumor growth inhibitory activity of macrophages exposed to adriamycin and adriamycin sensitivity of the target tumor cells. (1984) (38)
- Induction of nitric oxide synthase in the neo‐vasculature of experimental tumours in mice (1993) (38)
- Perspective: tumour spread—the problems of latency (1999) (37)
- Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands. (2007) (36)
- Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5. (2012) (36)
- Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues. (2008) (36)
- The role of E‐cadherin in low‐grade ductal breast tumourigenesis (2003) (35)
- Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. (2008) (34)
- Mechanisms underlying invasion and metastasis (1993) (32)
- Expression of NM23 in human melanoma progression and metastasis. (1996) (32)
- Stem/Progenitor Cell‐Like Properties of Desmoglein 3dim Cells in Primary and Immortalized Keratinocyte Lines (2007) (32)
- Effects of tumour cells on angiogenesis and vasoconstrictor responses in sponge implants in mice. (1992) (31)
- Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alphavbeta6: implications for infectiousness. (2008) (30)
- Species variability for toxicity of free and liposome-encapsulated muramyl peptides administered intravenously. (1985) (29)
- Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion (2011) (29)
- Mononuclear phagocyte adherence in the presence of laminin. A possible marker of cellular differentiation. (1983) (28)
- αvβ1 is a receptor for vitronectin and fibrinogen, and acts with α5β1 to mediate spreading on fibronectin (1995) (26)
- Tumor cell progression and differentiation in metastasis. (1991) (26)
- Modulation of human stromelysin 3 promoter activity and gene expression by human breast cancer cells (1997) (25)
- Therapy of human ovarian cancer xenografts with intraperitoneal liposome encapsulated muramyl-tripeptide phosphoethanolamine (MTP-PE) and recombinant GM-CSF. (1991) (24)
- Polyoma middle T abrogates TPA requirement of murine melanocytes and induces malignant melanoma. (1988) (24)
- Identification of genes controlling metastatic behaviour. (1991) (23)
- Metastatic behavior of an adriamycin-resistant murine tumor. (1983) (23)
- New evidence for tumour embolism as a mode of metastasis (2009) (23)
- The distribution of immunoglobulin-containing cells in canine small intestine. (1979) (23)
- The implications of tumor heterogeneity for studies on the biology of cancer metastasis. (1981) (22)
- A new role for the anti-apoptotic gene A20 in angiogenesis. (2006) (22)
- Laminin inhibits the adhesion of a murine tumor of macrophage origin. (1982) (22)
- The Integrins α3β1 and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells (2000) (21)
- Identification by differential display of a protein phosphatase‐2A regulatory subunit preferentially expressed in malignant melanoma cells (1999) (21)
- RhoC Interacts with Integrin α5β1 and Enhances Its Trafficking in Migrating Pancreatic Carcinoma Cells (2013) (20)
- Inhibited growth of a reticulum cell sarcoma (M5076) induced in vitro and in vivo by macrophage-activating agents. (1984) (19)
- The development of biological diversity and metastatic potential in malignant neoplasms. (1982) (19)
- Expression and function of the CD44 glycoprotein in melanoma cell lines (1993) (18)
- Inhibition of cellular division of a murine macrophage tumor by macrophage-activating agents. (1982) (18)
- The quantitative assessment of normal canine small intestinal mucosa. (1978) (17)
- Effect of tumour location on selective uptake and retention of phthalocyanines. (1989) (16)
- Fibronectin is chemotactic for CT 26 colon carcinoma cells: sub-lines selected for increased chemotaxis to fibronectin display decreased tumorigenicity and lung colonization (1998) (16)
- A v B 6 Integrin Promotes the Invasion of Morphoeic Basal Cell Carcinoma through Stromal Modulation (2008) (15)
- Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs (1986) (15)
- Effects of biologically active tumour-promoting and non-promoting phorbol esters on in vitro growth of melanocytic cells. (1989) (15)
- Comparative studies on the quantitative analysis of experimental metastatic capacity. (1983) (14)
- Toxicity studies of liposome-encapsulated immunomodulators administered intravenously to dogs and mice (2004) (14)
- Tumor cell hybridization and neoplastic progression. (1983) (14)
- Morphologic Studies on a Murine Reticulum Cell Sarcoma (Histiocytic Sarcoma) of Histiocytic Origin and its Metastases (1983) (13)
- Inhibition of [125I]epidermal growth factor binding to murine fibroblasts and keratinocytes by irradiation with UV-B light. Evidence for a protein kinase C-independent mechanism. (1990) (13)
- Adhesion characteristics of human melanoma cell lines of varying metastatic potential (1988) (13)
- DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential. (1986) (12)
- Host immunity in experimental metastasis (1978) (12)
- Activation status and function of the VLA‐4 (α4β1) integrin expressed on human melanoma cell lines (1997) (12)
- Long-term follow-up of ophthalmic Graves' disease. (1987) (12)
- Expression of cell surface P-glycoprotein by an Adriamycin-resistant murine fibrosarcoma (2004) (11)
- c-AMP-induced c-fos expression in cells of melanocyte origin. (1989) (11)
- Cell and tissue responses of a murine tumour to phthalocyanine-mediated photodynamic therapy. (1992) (11)
- Growth of melanocytic cells is associated with down-regulation of protein kinase C α,δ and ε isoforms: Possible role of diacylglycerol (1993) (11)
- Functional Analysis of a Breast Cancer-Associated FGFR2 Single Nucleotide Polymorphism Using Zinc Finger Mediated Genome Editing (2013) (11)
- Selectin ligands on human melanoma cells (1996) (11)
- Tumour angiogenesis and metastasis. (1991) (11)
- Divergent effects of flavone acetic acid on established versus developing tumour blood flow. (1991) (11)
- The role of animal models in the study of experimental metastasis (1982) (10)
- Different growth responses to agents which elevate cAMP in human melanoma cell lines of high and low experimental metastatic capacity (2005) (10)
- Management decisions in subclinical thyroid disease. (1995) (9)
- The early development of transient and permanent hypothyroidism following radioiodine therapy for hyperthyroid Graves' disease. (1984) (9)
- muc-1 gene expression in head and neck squamous cell carcinomas. (2000) (9)
- Protein kinase C levels and protein phosphorylation associated with inhibition of proliferation in a murine macrophage tumor (1990) (8)
- Differential induction of 12‐O‐tetradecanoylphorbol‐13‐acetate sequence gene expression in murine melanocytes and melanoma cells (1992) (8)
- β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear (2012) (8)
- Integrin a 5 b 1-Mediated Adenovirus Infection Is Enhanced by the Integrin-Activating Antibody TS 2 / 16 (1997) (8)
- Biology of tumor micrometastasis. (1996) (8)
- Immune profile in metastasis. (1989) (8)
- Value of free thyroxine (FT4), free triiodothyronine (FT3), and sensitive thyrotropin (TSH) assay in the assessment of optimal thyroxine therapy. (1987) (8)
- Activation status and function of the VLA-4 (alpha4beta1) integrin expressed on human melanoma cell lines. (1997) (7)
- Experimental metastasis and differentiation of murine melanoma cells: actions and interactions of factors affecting different intracellular signalling pathways (1994) (7)
- Gene therapy for lung cancer. (1995) (7)
- Tumour immunology: Molecular basis of tumour spread (1985) (6)
- Mast cell-tumour cell interactions: matrix degradation and the demonstration of histamine H2 receptors on human melanoma. (1988) (6)
- Reply: Early onset breast cancer in black British women: a letter to the editor of British Journal of Cancer regarding early onset of breast cancer in a group of British black women (2008) (6)
- Chronic active hepatitis and Graves' disease (1973) (6)
- Application of differential display, with in situ hybridization verification, to microscopic samples of breast cancer tissue (2003) (6)
- The collection, purification and characterization of canine peripheral blood monocytes. (1979) (6)
- Binding of canine IgM and IgG to protein A of Staphylococcus aureus: a simple method for the isolation of canine immunoglobulins from serum and the lymphocyte surface. (1979) (6)
- De novo expression of αvβ6 integrin by myoepithelial cells in ductal carcinoma in situ may be an important marker of disease progression (2008) (5)
- Metastatic Potential Cell Surface Properties of B 16 Melanoma Variants with Differing Updated (2006) (5)
- Thyrotoxicosis detected in a mass-screening program for neonatal hypothyroidism: demonstration of placental transfer of an immunoglobulin with marked lipolytic activity. (1977) (5)
- Protein kinase C-induced stimulation or inhibition of cellular proliferation in a murine macrophage tumor cell line. (1990) (5)
- Potential use of a charge-coupled device camera for imaging fluorescent dyes in vivo. (1991) (4)
- Role of integrins in tumor invasion and metastasis (2004) (4)
- The quantitative assessment of mucosa in canine small intestinal malabsorption. (1978) (4)
- Organ-specific metastasis of the b16 melanoma. Abstr. (1980) (4)
- Werner's The Thyroid: a Fundamental and Clinical Text (1987) (4)
- Recent observations on the pathogenesis of cancer metastasis. (1982) (4)
- Reply: Early onset of breast cancer in British black women (2008) (3)
- Rapid synthesis and biodistribution of [18F]-labelled linear peptides (2000) (3)
- Identification of Changes in Gene Expression Associated with Minimal Residual Disease (1999) (3)
- Investigation of signal transduction pathways involved in melanoma cell spreading. (2000) (3)
- The Role of Adhesion in Metastasis:: Potential Mechanisms and Modulation of Integrin Activity (1999) (3)
- The geographic full-time faculty system is dying: can we save it? (1984) (2)
- Tumour cell heterogeneity and the biology of metastasis. (1987) (2)
- Retinoic Acid-Induced Stellate Cell Quiescence Results in Sfrp4 Secretion Which Abrogates Wnt-β-Catenin Signalling Pathway Modulating Human Pancreatic Tumour Cell Behaviour (2011) (2)
- Structure-function analysis of RGD-helix motifs in αvβ6 integrin ligands (2007) (2)
- DCIS-Associated Myoepithelial Cells Expressing the αvβ6 Integrin Modify Tumour Cell Behaviour: A Predictor of Invasive Progression? (2009) (2)
- Signal transduction mechanisms involved in melanocytic cell growth and progression (1992) (2)
- High frequency of double drug resistance in the B16 melanoma cell line. (1990) (2)
- Induction of differentiation as a means of modifying metastatic behaviour. (1988) (2)
- Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer (2013) (2)
- Eating for two: How stromal fibroblasts might nurture adjacent carcinoma cells (2011) (2)
- Identification of the molecular signatures in cutaneous squamous cell carcinoma excised from patients with recessive dystrophic epidermolysis bullosa by using integrated genomic techniques. (2007) (1)
- β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear (2012) (1)
- Why do tumours metastasise (1987) (1)
- Transcriptionally targeted gene therapy. (1996) (1)
- Reply: Early onset of breast cancer in black British women: how reliable are the findings? (2008) (1)
- T1898 Organotypic Culture Modelling of Pancreatic Cancer (2008) (1)
- In vivo gene therapy of metastatic melanoma using the HSVtk gene by co-activation of anti-tumour immunity (1995) (1)
- The presence and distribution of beta-galactosidases in the small intestinal mucosa of the neonatal dog. (1977) (1)
- Locomotory Behavior of a BI6 Melanoma Variant Line Selected for Increased Invasiveness (1980) (1)
- Kindlin-1 is a migfilin-binding protein which associates with kindlin-2 at focal contacts (2007) (1)
- Molecular basis of tumour spread. (1985) (1)
- The Pemphigus Vulgaris antigen desmoglein-3 suppresses p53 function via the YAP-Hippo pathway (2018) (1)
- Myoepithelial Cells in DCIS Exhibit an Altered Phenotype and Promote Angiogenesis. (2009) (1)
- Potent, selective inhibitors of human gelatinase and their potential in the treatment of tumour metastases (1994) (1)
- Description of Specific Diseases (1983) (1)
- The effects of intravenous administration of Methanol Extraction Residue (MER) of tubercle bacilli in the dog (2004) (1)
- Expression of PAX-3 alternatively spliced transcripts in human tumours of neural crest origin. (2001) (1)
- Pointers to metastasis (1987) (1)
- THE USE OF NUDE MICE TO ASCERTAIN THE MALIGNANT CAPACITY OF HUMAN COLON CANCER (1986) (1)
- A role for A20 in tumour angiogenesis (2004) (1)
- The Selection and Characterization of an Invasive Variant of the Bi 6 Melanoma (2007) (1)
- Mechanisms of antitumor action of interferons on human tumour xenografts and in mouse metastases models (1987) (1)
- The Invasive Phenotype of Malignant Cells (1990) (1)
- History and Physical Examination (1983) (0)
- FROM THE BIOLOGY OF METASTASIS LABORATORY, IMPERIAL CANCER RESEARCH FUND, LINCOLN'S INN (1990) (0)
- S2 INTEGRIN-MEDIATED MIGRATION AND INVASION OF TUMOUR CELLS AND ENDOTHELIAL CELLS (2004) (0)
- 14. [18F]-Labelled linear peptides containing the RGD sequence: Rapid synthesis and biodistribution (2000) (0)
- Abstract P4-15-01: Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy (2013) (0)
- A tropism-modified, CAR-detargeted Ad5 vector which displays reduced hepatotropism and an optimal profile has an improved therapeutic index compared with Ad5 (2012) (0)
- Metastatic Phenotype and Cell Differentiation in Melanoma Cells (1989) (0)
- The Ratio of Pancreatic Stellate Cells to Pancreatic Cancer Cells Plays a Critical Role in Modulating Carcinoma Cell Behaviour (2011) (0)
- 340 Role of adhesion receptors in tumour spread (1995) (0)
- The Role of Recertification and Relicensure Programs in the Maintenance of Competence (1991) (0)
- Proliferating cellnuclear antigen expression innon-cycling cells maybe induced bygrowth factors invivo (1994) (0)
- Plakophilin 1 affects keratinocyte migration, but not proliferation, in an in vitro wound-healing model. (2002) (0)
- Role of cell adhesion molecules in melanoma progression and dissemination: 79 (1993) (0)
- Exhibiting Organ-specific Growth Metastatic Behavior of a Murine Reticulum Cell Sarcoma (2013) (0)
- Identification ofgenescontrolling metastatic behaviour (1991) (0)
- P26 24 WP – MELANOCYTE BASED SYSTEM TO STUDY THE EFFECTS OF RADIATION EXPOSURE ON NORMAL CELL GROWTH AND TRANSFORMATION (1991) (0)
- Generation of a single-chain Fv with binding specificity for the integrin, alpha v beta 6, by rational structure based antibody engineering – a promising agent for cancer therapy (2007) (0)
- Selection and preliminary characterization of variant lines of a murine macrophage tumor resistant to the antiproliferative effects of phorbol esters. (1990) (0)
- The biology of melanoma invasion and metastasis (1995) (0)
- Upregulation of alpha-v-beta 6 integrin promotes invasion of morphoeic basal cell carcinomas indirectly through stromal modulation (2008) (0)
- The Presentation of Endocrine Disease and the Diagnostic Possibilities (1983) (0)
- S1890 A Novel Interaction of Ezrin with Cortactin in Podosomal Rosette Assembly in Pancreatic Cancer Cells (2008) (0)
- A systematic approach to developing a diploma examination in sports medicine. (1989) (0)
- Therapie de tumeurs (1993) (0)
- Methylation status of p16 in breast cancer cell lines, normal breast tissue, breast tumours and lymphocytes (2000) (0)
- 37 Combination gene therapies for the treatment of malignant melanoma in vivo (1995) (0)
- The ss 6 integrin subunit C-terminal 11 amino acids are sufficient to promote invasion by squamous cell carcinoma (SCC) cells (2002) (0)
- PP-1-14 Integrins αvβ1 and αvβ5 function as breast cancer cell vitronectin receptors (1996) (0)
- On the threshold of success? Report on ECCO8, 29 October–2 November 1995, Paris, France (1996) (0)
- Antibody targeted magnetic nanoparticles for cancer imaging and therapy (2007) (0)
- Gelatinase inhibitors and tumour metastasis (1995) (0)
- Editorial: Special Section on “Site‐Specific Metastasis” (2011) (0)
- Functional analysis of normal and DCIS modified breast myoepithelial cells (2006) (0)
- Cell Adhesion Receptors and Melanoma Dissemination (1992) (0)
- An in vitro 3D-Model of Invasive Squamous Cell Carcinoma (SCC) Recapitulates in vivo Pathology (2003) (0)
- PP-1-2 Modulation of human stromelysin-3 (ST3) promoter activity by human breast cancer cell conditioned medium (1996) (0)
- An Introduction to Tumor Progression (2017) (0)
- Abstract B80: Targeting pancreatic cancer stroma with histone deacetylase inhibitors. (2012) (0)
- Serum protein-bound iodine levels in adolescents. (1967) (0)
- Book Review:Proteinases and Tumor Invasion. Peter Strauli, Alan J. Barrett, Antonio Baici (1981) (0)
- Melanomas following Direct Intratumoral Injection of DNA MurineThymidine Kinase Gene to Inhibit Growth of Established Use of Tissue-specific Expression of the Herpes Simplex Virus (2006) (0)
- Gene therapy for lung cancer. Discussion (1995) (0)
- S1891 RhoC Enhances Pancreatic Carcinoma Cell Migration By Mediating Integrin Signaling and Podosome Formation (2008) (0)
- 255 INVITED Targeting the invasio-association integrin alphavbeta6 as an anti-carcinoma strategy (2006) (0)
- Abstract B42: Toward targeting integrin αvβ6 for the therapy of pancreatic cancer. (2012) (0)
- EP4-mediated prostanoid signalling promotes oral cancer progression (2010) (0)
- Melanoma progression: role of signal transduction pathways in transformation, differentiation, and malignancy. (1989) (0)
- Adhesion-dependent cell cycle control of melanocyte-derived cell lines (2000) (0)
- Background to Endocrine Disease (1983) (0)
- Targeting pancreatic cancer stroma by HDAC inhibitors (2013) (0)
- 162 Reduction of TSG101 protein by RNA interference has a negative impact on prostate cancer cell growth (2004) (0)
- Expression of PAX3 spliced transcripts in human tumours of neural crest origin (2001) (0)
- Corrigendum. (2019) (0)
- Book Review:Cancer: A Comprehensive Treatise. Volume 1 (Etiology: Chemical and Physical Carcinogenesis). Frederick F. Becker (1982) (0)
- PP-1-13 Breast cancer cell mediated control of human stromelysin 3 (ST3) promoter activity (1996) (0)
- Biochemical association between kindlin-1, kindlin-2 and migfilin and relevance to Kindler syndrome (2007) (0)
- Insulins in New Zealand: a plea for rationalisation. (1978) (0)
- Genetics of cancer—Special issue (1994) (0)
- Role of adhesion and migration in melanoma metastasis: 185 (1997) (0)
- Cell adhesion, motility and cancer (1996) (0)
- Expression of the a v b 6 Integrin Promotes Migration and Invasion in Squamous Carcinoma Cells (2010) (0)
- The Principles of General Management and Treatment (1983) (0)
- P2-01-05: Integrin avb6 Mediates HER2−Driven Invasion in Breast Cancer. (2011) (0)
- HAX-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin v6 (2007) (0)
- The integrin αvβ6 identifies a novel poor prognosis subset in breast cancer and is a promising new therapeutic target. (2007) (0)
- Isolation and Preliminary Characterization of an Adriamycin-resistant Murine Fibrosarcoma Cell Line 1 (2006) (0)
- RNA interference of TSG101 gene expression reduces prostate cancer invasion in vitro (2003) (0)
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What Schools Are Affiliated With Ian R. Hart?
Ian R. Hart is affiliated with the following schools:
