A. Ian Scott
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Scotland-born chemist
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(Suggest an Edit or Addition)According to Wikipedia, Alastair Ian Scott was a British-American organic chemist who achieved international renown for elucidating the biosynthetic pathway of vitamin B12. He occupied successive chairs of organic chemistry at the universities of British Columbia, Sussex, and Yale before moving to Texas A&M University in 1977. In 1980 he occupied the Forbes chair of organic Chemistry at the University of Edinburgh. He was named a distinguished professor of chemistry and biochemistry in 1981 at Texas A&M University, and remained there until the end of his career.
A. Ian Scott's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Interpretation of the ultraviolet spectra of natural products (1964) (467)
- Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. (2001) (199)
- Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus. (1990) (165)
- Biosynthesis of the indole alkaloids. (1965) (126)
- Tetrapyrrole assembly and modification into the ligands of biologically functional cofactors. (1990) (107)
- The Escherichia coli cysG gene encodes S-adenosylmethionine-dependent uroporphyrinogen III methylase. (1990) (103)
- The Escherichia coli cysG gene encodes the multifunctional protein, siroheme synthase (1993) (99)
- Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein. (1994) (96)
- Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium. (2003) (94)
- Sterol carrier protein-2: structure reveals function (2002) (93)
- Structure of the Methanococcus jannaschii Mevalonate Kinase, a Member of the GHMP Kinase Superfamily* (2002) (86)
- A symmetry rule for chiral olefins (1969) (84)
- Biosynthesis of cobalamin (vitamin B(12)). (2001) (81)
- NMR and molecular modeling study of the conformations of taxol and of its side chain methylester in aqueous and non-aqueous solution. (1993) (77)
- The condensation reaction between isocyanates and carboxylic acids. A practical synthesis of substituted amides and anilides. (1986) (75)
- Purification and properties of strictosidine synthetase (an enzyme condensing tryptamine and secologanin) from Catharanthus roseus cultured cells. (1979) (71)
- The structure and chemistry of hirsutic acid. (1967) (70)
- How Nature Synthesizes Vitamin B12 ? A Survey of the Last Four Billion Years (1993) (68)
- The constitution of monorden, an antibiotic with tranquilising action (1964) (68)
- Biosynthesis of vitamin B12 (1993) (67)
- Enzymatic synthesis of dihydrosirohydrochlorin (precorrin‐2) and of a novel pyrrocorphin by uroporphyrinogen III methylase (1990) (64)
- 13 C n.m.r. evidence for a new intermediate, pre-uroporphyrinogen, in the enzymic transformation of porphobilinogen into uroporphyrinogens I and III (1979) (63)
- Biogenetic-type synthesis of the Calycanthaceous alkaloids. (1967) (62)
- Intracellular Sterol Binding Proteins: Cholesterol Transport and Membrane Domains (1998) (62)
- cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation (2002) (61)
- Pre-uroporphyrinogen: a substrate for uroporphyrinogen III cosynthetase (1979) (61)
- Cloning, sequencing, and expression of the uroporphyrinogen III methyltransferase cobA gene of Propionibacterium freudenreichii (shermanii) (1995) (61)
- The sterol carrier protein-2 fatty acid binding site: an NMR, circular dichroic, and fluorescence spectroscopic determination. (1997) (58)
- Fine-Tuning Our Knowledge of the Anaerobic Route to Cobalamin (Vitamin B12) (2006) (57)
- Discovering nature's diverse pathways to vitamin B12: a 35-year odyssey. (2003) (56)
- How corrinoids are synthesized without oxygen: nature's first pathway to vitamin B12. (1997) (54)
- Biosynthesis of corrins. II. Incorporation of 13C-labeled substrates in vitamins B12. (1974) (53)
- Identification and Characterization of a Novel Vitamin B12 (Cobalamin) Biosynthetic Enzyme (CobZ) from Rhodobacter capsulatus, Containing Flavin, Heme, and Fe-S Cofactors* (2005) (53)
- Overproduction, in Escherichia coli, of soluble taxadiene synthase, a key enzyme in the Taxol biosynthetic pathway. (1998) (52)
- Chimonanthine. A One-Step Synthesis and Biosynthetic Model (1964) (52)
- Holo-sterol Carrier Protein-2 (1999) (52)
- Site-directed mutagenesis and high-resolution NMR spectroscopy of the active site of porphobilinogen deaminase. (1988) (52)
- Mechanistic and evolutionary aspects of vitamin B12 biosynthesis (1990) (52)
- Carbon-13 as a label in biosynthetic studies. (1974) (51)
- Modification of proteases to esterases for peptide synthesis: methylchymotrypsin (1988) (50)
- Pharmacological studies with vinblastine in the dog. (1975) (49)
- Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis Identification of the 11‐methyl and 20‐methyl transferases of corrin biosynthesis (1992) (48)
- Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii). (2002) (47)
- Biotransformation of geraniol, nerol and (+)- and (−)-carvone by suspension cultured cells of Catharanthus roseus (1997) (46)
- Biosynthesis of Natural Products (1974) (45)
- Enzymatic synthesis and structure of precorrin-3, a trimethyldipyrrocorphin intermediate in vitamin B12 biosynthesis. (1992) (45)
- NMR and molecular modeling study of active and inactive taxol analogues in aqueous and nonaqueous solution (1994) (45)
- Identification of a cysteine residue as the binding site for the dipyrromethane cofactor at the active site of Escherichia coli porphobilinogen deaminase (1988) (44)
- Structure and stereochemistry of tetrahedral inhibitor complexes of papain by direct NMR observation (1983) (44)
- Stereochemistry of the diterpenoids—IV (1964) (44)
- Genetically engineered synthesis of precorrin-6x and the complete corrinoid, hydrogenobyrinic acid, an advanced precursor of vitamin B12. (1994) (44)
- Sequence of the Candida albicans erg7 gene. (1993) (44)
- Facile and highly selective 5′-desilylation of multisilylated nucleosides (2000) (43)
- Biogenetic-type synthesis of the indole alkaloids (1974) (42)
- Sirohydrochlorin. Prosthetic group of sulfite and nitrite reductases and its role in the biosynthesis of vitamin B12 (1978) (41)
- Characterization of a 5-methyltryptophan resistant strain of Catharanthus roseus cultured cells (1979) (41)
- Electrooxidation of Tyrosyl Derivatives: A Model for Coumarin Biosynthesis (1963) (41)
- Enzymatic synthesis of S-adenosyl-L-methionine on the preparative scale. (1996) (41)
- Studying enzyme mechanism by 13C nuclear magnetic resonance. (1984) (40)
- Sirohydrochlorin. Prosthetic group of a sulfite reductase enzyme and its role in the biosynthesis of vitamin B12. (1978) (40)
- Conformation in solution and dynamics of a structurally constrained linear insect kinin pentapeptide analogue. (1999) (39)
- Reconstitution of apo‐porphobilinogen deaminase: Structural changes induced by cofactor binding (1989) (39)
- Role of anhydrovinblastine in the biosynthesis of the antitumor dimeric indole alkaloids (1978) (39)
- Biosynthesis of corrinoids. Concerning ithe origin of the methyl groups in vitamin B 12 . (1972) (38)
- Overexpression, purification, and characterization of the thermostable mevalonate kinase from Methanococcus jannaschii. (1999) (38)
- Timing of cobalt insertion in vitamin B12 biosynthesis (1991) (37)
- Hydroxylation of piperitone by cell suspension cultures of Catharanthus roseus (1994) (36)
- The Role of Isovincoside (Strictosidine) in the Biosynthesis of the Indole Alkaloids (1977) (36)
- Multiple biosynthetic pathways for vitamin B12: variations on a central theme. (2001) (36)
- Effects of bioregulators on indole alkaloid biosynthesis in Catharanthus roseus cell culture (1981) (36)
- Structural characterization of novel cobalt corrinoids synthesized by enzymes of the vitamin B12 anaerobic pathway. (2006) (35)
- The mechansim of action of coenzyme B12. The role thioester in a nonenzyme model reaction for coenzyme B12 Dependent isomerization of methylmalony coenzyme A to succinyl coenzyme A. (1977) (34)
- Isolation, structure, and genetically engineered synthesis of precorrin-5, the pentamethylated intermediate of vitamin B12 biosynthesis (1993) (34)
- 5‐Aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum (1988) (34)
- 13C NMR study of the stereospecificity of the thiohemiacetals formed on inhibition of papain by specific enantiomeric aldehydes. (1986) (34)
- Stereochemistry of olefins—IX : Correlation of Mills' and Brewster's rules with the Cotton effects of cyclic olefins☆ (1971) (34)
- Deoxygenation of phenolic natural products. Enzymic conversion of emodin to chrysophanol (1988) (33)
- Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes. (1995) (33)
- Biosynthesis of polyketides. Purification and inhibition studies of 6-methylsalicylic acid synthase (1974) (32)
- INTERPRETATION OF THE ULTRAVIOLET SPECTRA OF SOME COMPLEX MOLECULES (1964) (31)
- Achieving natural product synthesis and diversity via catalytic networking ex vivo. (1996) (31)
- Temporal resolution of the methylation sequence of vitamin B12 biosynthesis (1989) (31)
- Carbon-13 nuclear-magnetic-resonance studies of glucose catabolism by Trypanosoma brucei gambiense. (1982) (31)
- Pyrone studies—I (1967) (31)
- Quantitation of cocaine in a variety of matrices by high-performance liquid chromatography (1981) (30)
- Mechanisms of indole alkaloid biosynthesis. The Corynanthe-Strychnos relationship. (1969) (30)
- 13C NMR study of the ionizations within a trypsin-chloromethyl ketone inhibitor complex. (1985) (30)
- Biosynthesis of vitamin B12: Timing of the methylation steps between uro'gen III and cobyrinic acid (1984) (30)
- Absolute stereochemistry of the bisindole alkaloids of the vinblastine type. Circular dichroism studies (1975) (30)
- Detection of a tetrahedral adduct in a trypsin-chloromethyl ketone specific inhibitor complex by carbon-13 NMR (1983) (29)
- Synthesis, biological activity, and conformational studies of insect allatostatin neuropeptide analogues incorporating turn-promoting moieties. (1998) (29)
- Genetically engineered synthesis of natural products (1993) (29)
- 20-Methylsirohydrochlorin. A revised structure for a trimethylisobacteriochlorin intermediate (factor III) in the biosynthesis of vitamin B12 (1979) (29)
- Self-condensation of activated malonic acid half esters: a model for the decarboxylative Claisen condensation in polyketide biosynthesis (2003) (29)
- The biosynthesis of patulin (1973) (29)
- Biogenesis of Strychnos, Aspidosperma, and Iboga alkaloids. The structure and reactions of preakuammicine. (1969) (29)
- Biosynthesis of vitamin B12: ring contraction is preceded by incorporation of molecular oxygen into precorrin-3 (1993) (29)
- 894. Metabolic products of penicillium patulum (1960) (28)
- Biosynthesis of vitamin B12: factor IV, a new intermediate in the anaerobic pathway. (1996) (28)
- 363. The constitutions of geodin and erdin (1958) (28)
- Crystal structure of precorrin-8x methyl mutase. (2001) (28)
- Biosynthesis of vitamin B12. In search of the porphyrin-corrin connection (1978) (27)
- Characterization of Alkaloid Uptake by Catharanthus roseus (L.) G. Don Protoplasts. (1988) (27)
- Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes. (2006) (26)
- Citlalitrione, a new diterpene from Jatropha dioica var. sessiliflora. (1988) (26)
- Biosynthesis of strychnine (1973) (26)
- Indole aldaloid biosynthesis: partial purification of "ajmalicine synthetase" from Catharanthus roseus. (1977) (26)
- Total synthesis of colchicine modelled on a biogenetic theory. (1965) (26)
- Laboratory model for the biosynthesis of vallesamine, apparicine, and related alkaloids (1978) (26)
- Simulation of the Biosynthesis of Tetracyclines. A Partial Synthesis of Tetracycline from Anhydroaureomycin (1962) (25)
- Formation of catharanthine, akuammicine and vindoline in Catharanthus roseus suspension cells (1980) (25)
- Letter: Biosynthesis of uroporphyrinogen III from porphobilinogen. Resolution of the enigmatic "switch" mechanism. (1976) (25)
- Structure and biogenetic-type synthesis of andranginine: an indole alkaloid of a new type (1974) (25)
- Synthesis of the 2-fluoro-11-hydroxy analog of porphobilinogen, a new suicide inhibitor of the enzyme porphobilinogen deaminase (1994) (25)
- Diastereotopic covalent binding of the natural inhibitor leupeptin to trypsin: detection of two interconverting hemiacetals by solution and solid-state NMR spectroscopy. (1991) (25)
- Concerning the catalytic site of porphobilinogen deaminase (1988) (25)
- Biosynthesis of vitamin B12: concerning the identity of the two-carbon fragment eliminated during anaerobic formation of cobyrinic acid. (1996) (24)
- Tetrahedron report : Concerning the biosynthesis of vitamin B12 (1975) (24)
- Conversion of anhydrovinblastine to vinblastine by cell-free homogenates of catharanthus roseus cell suspension cultures (1983) (24)
- Timing and mechanistic implications of regiospecific carbonyl oxygen isotope exchange during vitamin B12 biosynthesis (1991) (24)
- A general synthesis of β-aryl and heteroarylpyrroles by palladium-catalyzed coupling reaction of β-tributylstannylpyrrole with aryl and heteroaryl halides (1996) (24)
- Studies on taxadiene synthase: interception of the cyclization cascade at the verticillene stage and rearrangement to phomactatriene (2007) (24)
- Kukulkanins A and B, new chalcones from Mimosa tenuefolia. (1989) (23)
- Studies on taxadiene synthase: interception of the cyclization cascade at the isocembrene stage with GGPP analogues. (2005) (23)
- The structure of the antibiotic hedamycin I. Chemical, physical and spectral properties. (1977) (23)
- Genetically engineered synthesis of natural products: from alkaloids to corrins. (1996) (23)
- Diversity in cyclic sesquiterpene production by Gossypium hirsutum. (1995) (23)
- 13C nuclear magnetic resonance studies of anaerobic glycolysis inTrypanosoma brucei spp. (1983) (23)
- Structure of factor S3, a metabolite of Propionibacterium shermanii derived from uroporphyrinogen I (1986) (22)
- Fluoro-decarboxylation of pyrrolecarboxylic acids by F–TEDA–BF4– a convenient general synthesis of fluoropyrroles (1995) (22)
- Genetically Engineered Production of 1-Desmethylcobyrinic Acid, 1-Desmethylcobyrinic Acid a,c-Diamide, and Cobyrinic Acid a,c-Diamide in Escherichia coli Implies a Role for CbiD in C-1 Methylation in the Anaerobic Pathway to Cobalamin* (2005) (22)
- Mechanisms of indole alkaloid biosynthesis. Recognition of intermediacy and sequence by short-term incubation (1971) (22)
- NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. (1996) (22)
- Stereochemistry of the Diterpenoids: Absolute Configuration of Cafestol (1962) (22)
- Chemistry of Polypyrones. A Model for Acetogenin Biosynthesis (1965) (22)
- Purification of an indole alkaloid biosynthetic enzyme, strictosidine synthase, from a recombinant strain of Escherichia coli. (1992) (21)
- Biotransformation of testosterone isomers by a green cell suspension culture of Marchantia polymorpha (1991) (21)
- Improved separation of uroporphyrin isomers by high-performance liquid chromatography (1980) (21)
- Biosynthesis of patulin. Dehydrogenase and dioxygenase enzymes of penicillium patulum (1974) (21)
- Comparison of Ring Current Methods for Use in Molecular Modeling Refinement of NMR Derived Three-Dimensional Structures (1998) (21)
- On B12 biosynthesis and evolution. (1977) (21)
- Definition of the redox states of cobalt-precorrinoids: investigation of the substrate and redox specificity of CbiL from Salmonella typhimurium. (1998) (21)
- Biosynthesis of the fungal tropolones. Stipitatic and stipitatonic acids. (1971) (20)
- Biosynthesis of corrins. A cell-free system from Propionibacterium shermanii. (1973) (20)
- Biosynthesis of porphyrins and corrins. 2. Isolation, purification, and NMR investigations of the porphobilinogen-deaminase covalent complex. (1986) (20)
- Letter: Acetyl transfer reaction in catechol acetate malonate. A model for the biosynthesis of polyketides and fatty acids. (1975) (20)
- Circular dichroism studies on cuprammonium complexes of diols and amino-alcohols (1970) (20)
- A new derivative of glucose and 2-C-methyl-D-erythritol from Ferula sinaica. (1996) (20)
- Mechanism of action of coenzyme B12. An overall anionic mechanism for carbon-skeleton rearrangement in a model reaction (1978) (19)
- THE STRUCTURE OF FACTOR III: A TRIMETHYL ISOBACTERIOCHLORIN INTERMEDIATE IN THE BIOSYNTHESIS OF VITAMIN B12† (1981) (19)
- Cryoenzymology of proteases: NMR detection of a productive thioacyl derivative of papain at subzero temperatures (1982) (19)
- Factor S1, a natural corphin from Propionibacterium shermanii (1987) (19)
- Stereochemistry of olefins—VIII : Determination of the absolute configuration of square planar complexes (1971) (19)
- Reactivity of peptide hydroxamates: A model for the biosynthesis of β-lactam antibiotics (1976) (19)
- Biosynthesis of polyketides the synthesis of 6-methylsalicylic acid and triacetic acid lactone in Penicillium patulum (1971) (19)
- Regio- and stereospecific models for the biosynthesis of the indole alkaloids—II : Biogenetic type synthesis of Aspidosperma and Iboga alkaloids from a corynanthe precursor (1974) (19)
- The discovery of nature's pathway to vitamin B12. A 25 year odyssey (1994) (19)
- Fluorination of pyrrolic compounds with xenon difluoride (1994) (18)
- Chemical Aspects of Enzyme Biotechnology (1990) (18)
- On the mechanism of porphobilinogen deaminase. Design, synthesis, and enzymatic reactions of novel porphobilinogen analogs. (1992) (18)
- 793. Oxidative pairing of phenolic radicals. Part I. The total synthesis of griseofulvin (1961) (18)
- Mechanism of the Ring Contraction Step in Vitamin B12 Biosynthesis: The Origin and Subsequent Fate of the Oxygen Functionalities in Precorrin-3x (1994) (18)
- Application of CMR spectroscopy to the study of porphyrin and corrin biosynthesis in vitro and in vivo (1981) (18)
- Biosynthesis of corrins. I. Experiments with 14-C porphobilinogen and 14-C uroporphyrinogens. (1974) (18)
- Genetically Engineered Synthesis of Complex Natural Products (1992) (18)
- Stereochemistry of methyl group insertion in corrinoid biosynthesis. Determination of carbon isotope chirality by 13C nuclear magnetic resonance. (1973) (17)
- Biosynthesisfof indole alkaloids. Vindoline. (1968) (17)
- Structure of preuroporphyrinogen. Exploration of an enzyme mechanism by carbon-13 and nitrogen-15 NMR spectroscopy (1979) (17)
- Observation of enzyme bound intermediates in the biosynthesis of preuroporphyrinogen by PBG deaminase (1991) (17)
- Conformational studies of N-benzoyl-L-phenylalanine by combined rotation and multiple-pulse spectroscopy proton nuclear magnetic resonance (1990) (17)
- Use of high-performance liquid chromatography to quantitate the opiate and sugar content of illicit heroin preparations. (1983) (17)
- Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced glucose metabolism in MCF-7 human breast cancer cells: 13C nuclear magnetic resonance spectroscopy studies. (1991) (17)
- Conformational studies of paclitaxel analogs modified at the C-2' position in hydrophobic and hydrophilic solvent systems. (1997) (16)
- Partial purification and characterization of oxidosqualene-lanosterol cyclase from bakers yeast (1991) (16)
- Study of the cotton effect of 16-substituted 20-keto pregnane and 17α-pregnane derivatives☆ (1964) (16)
- Synthesis of (±)-eicosa-cis-8,9-(11, 12- and 14, 15-)epoxy-cis-11, 14-(8, 14- and 8, 11-) dienoic acids and attempted bioconversion to prostaglandins (1974) (16)
- Preparation of aminated taxol side chain precursors. A Simple Approach to 2,3-Diamond Acids Using the β-Lactam Synthon Method. (1997) (16)
- Aqueous trifluoroacetic acid—an efficient reagent for exclusively cleaving the 5′-end of 3′,5′-TIPDS protected ribonucleosides (2000) (16)
- Comparison of insect kinin analogs with cis-peptide bond motif 4-aminopyroglutamate identifies optimal stereochemistry for diuretic activity. (2007) (16)
- Uroporphyrinogen III methylase catalyzes the enzymatic synthesis of sirohydrochlorins II and IV by a clockwise mechanism (1990) (16)
- Evidence for conformational changes in Escherichia coli porphobilinogen deaminase during stepwise pyrrole chain elongation monitored by increased reactivity of cysteine-134 to alkylation by N-ethylmaleimide. (1995) (16)
- Development of an ‘overmethylation’ strategy for corrin synthesis. Multi-enzyme preparation of pyrrocorphins (1990) (16)
- Decarboxylative Claisen condensation catalyzed by in vitro selected ribozymes. (2006) (15)
- Biosynthesis of indole alkaloids: sequential precursor formation and biological conversion in Vinca rosea (1968) (15)
- How were porphyrins and lipids synthesized in the RNA world (1997) (15)
- Biosynthesis of the antitumour catharanthus alkaloids. Conversion of anhydrovinblastine into vinblastine (1979) (15)
- Regio- and stereospecific models for the biosynthesis of the indole alkaloids—III (1974) (15)
- Efficient one-step syntheses of isoprenoid conjugates of nucleoside 5'-diphosphates. (2003) (14)
- 13C NMR studies of glycolysis in intra- and extra-erythrocytic Babesia microti. (1984) (14)
- An Improved Procedure for the Epoxidation of Methyl Cinnamate Derivatives and Production of Acid Sensitive Epoxides (1996) (14)
- INDOLE ALKALOID BIOSYNTHESIS (1981) (14)
- Synthesis of oxa analogs of porphobilinogen (PBG) as probes for mechanistic studies of PBG deaminase (1993) (14)
- Overexpression, single-step purification, and site-directed mutagenetic analysis of casbene synthase. (1998) (14)
- 1H, 3H and 13C NMR studies on porphobilinogen (1985) (14)
- An efficient synthesis of δ-aminolevulinic acid (ALA) and its isotopomers (1997) (14)
- N.m.r. spectroscopy as a probe for the study of enzyme-catalysed reactions. Further observations of preuroporphyrinogen, a substrate for uroporphyrinogen III cosynthetase (1980) (14)
- Interconversion of Corynanthe, aspidosperma, and Iboga alkaloids. A model for indole alkaloid biosynthesis (1968) (14)
- Cryoenzymology of trypsin. 13C-n.m.r. detection of an acyl-trypsin intermediate in the trypsin-catalysed hydrolysis of a highly specific substrate at subzero temperature. (1984) (14)
- An efficient synthesis of 3-vinylpyrroles by Stille coupling reaction of 3-iodopyrroles with vinyltributyltin† (1995) (14)
- Structure and absolute configuration of (+)-coronaridine hydrobromide. Absolute configuration of the Iboga alkaloids (1973) (13)
- Absolute Stereochemistry of Precorrin-3x and Its Relevance to the Dichotomy of Ring Contraction Mechanism in Vitamin B12 Biosynthesis (1996) (13)
- Cryoenzymology of trypsin. A detailed kinetic study of the trypsin-catalysed hydrolysis of N-alpha-benzyloxycarbonyl-L-lysine p-nitrophenyl ester at low temperatures. (1983) (13)
- A mass-spectrometric study of biosynthesis: conversion of deutero-m-cresol into patulin (1967) (13)
- Overcoming product inhibition of S-Adenosyl-L-methionine (SAM) synthetase: Preparation of SAM on the 30 mM scale (1995) (13)
- Inhibition of trypsin by carbobenzyloxylysyl chloromethyl ketone: 13C NMR and x-ray diffraction analyses of the enzyme-inhibitor complex (1986) (13)
- AN IMPROVED SYNTHESIS OF THE DINUCLEOTIDES pdCpA AND pdCpdA (2001) (13)
- Stereospecific synthesis of chiral acetic acid from glycine (1978) (12)
- Further observations on the biogenetic-type chemistry of the indole alkaloids. (1969) (12)
- CMR as a Probe for Metabolic Pathways in vivo (1983) (12)
- A New Type of Cytotoxic Immunosuppressive Agent: 3-Acetyl-5-(4-fluorobenzylidene)4-hydroxy-2-oxo-2:5-dihydrothiophen (1966) (12)
- Evidence for an intermediate in the enzymatic formation of uroporphyrinogen III. (1994) (12)
- Use of Montmorillonite clay for the synthesis of linear tetrapyrroles and their cyclization to Uroporphyrinogens (1994) (12)
- An efficient synthesis of 4(5),11(12)-taxadiene derivatives and microbial mediated 20-hydroxylation of taxoids (2000) (12)
- Development of Weiner et al. Force Field Parameters Suitable for Conformational Studies of [1, 4]-Benzodiazepines and Related Compounds (1997) (12)
- Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids. Topics in Current Chemistry. Vol. 209 Edited by Finian J. Leeper (University of Cambridge) and John C. Vederas (University of Alberta). Springer-Verlag: Berlin, Heidelberg, New York. 2000. viii + 247 pp. $159.00. ISBN 3-540-66573-0. (2000) (12)
- 521. An approach to the partial synthesis of aldosterone from steroids lacking substitution at C18 (1957) (12)
- Regio- and stereospecific models for the biosynthesis of the indole alkaloids—III : The Aspidosperma-Iboga-secodine relationship (1974) (12)
- Chemical synthesis and papain-catalysed hydrolysis of N-alpha-benzyloxycarbonyl-L-lysine p-nitroanilide. (1985) (12)
- Reflections on the discovery of nature's pathways to vitamin B12. (2001) (11)
- Synthesis of Hydroaromatic Compounds Containing Angular Methyl Groups. V. Equilenin Series (1956) (11)
- Synthesis of difluoroalkylpyrrolic compounds from (diethylamino)sulfur trifluoride and acylpyrroles (1995) (11)
- Preparation of pyrrolin-2-ones and 4,5-dihydrodipyrrin-1-ones by oxidation of α-formylpyrroles and α-formyldipyrromethanes with hydrogen peroxide (2000) (11)
- Concerning the terpenoid origin of indole alkaloids: biosynthetic mapping by direct mass spectrometry (1966) (11)
- Biosynthesis of vitamin B12: concerning the origin of the methine protons of the corrin nucleus. (1987) (11)
- Direct non-invasive observation of metabolism in living cells by 13C nuclear magnetic resonance spectroscopy (1980) (11)
- Multienzyme Synthesis and Structure of Factor S3 (1993) (11)
- 149. Tropolones. Part II. The synthesis of α-, β-, and γ-thujaplicins (1951) (11)
- Laboratory model for the biogenesis of the antipodal strychnos alkaloids (1974) (11)
- Total synthesis of corallistin A (1991) (11)
- Mutagenesis identifies a conserved tyrosine residue important for the activity of uroporphyrinogen III synthase from Anacystis nidulans (2002) (11)
- Biosynthesis of Colchicine (1960) (11)
- On the Duality of Mechanism of Ring Contraction iv Vitamin B12 Biosysthesis (1994) (11)
- Synthesis and reactions of thioaldehyde dehydropeptides related to β-lactam antibiotics (1974) (10)
- Isolation and identification of xochitloldione and isoxochitlolone from Cnidosculus urens. (1992) (10)
- The structure of sirohydrochlorin I, a dimethylisobacteriochlorin derived from uroporphyrinogen I (1989) (10)
- Genetic and Mechanistic Exploration of the Two Pathways of Vitamin B 12 Biosynthesis (2003) (10)
- The methylation process in corrin biosynthesis. Application of 1H{13C} nuclear magnetic resonance difference spectroscopy to a biochemical problem (1976) (10)
- Conformation of vinblastine in aqueous solution determined by 2D 1H- and 13C-NMR spectroscopy (1992) (10)
- Bacteriochlorophyll c formation via the C5 pathway of 5‐aminolevulinic acid synthesis in Chloroflexus aurantiacus (1991) (10)
- Fluorescence-based method for selection of recombinant plasmids. (1995) (10)
- CHAPTER 2 – CONJUGATED CHROMOPHORES (1964) (10)
- Concerning the biosynthesis of vitamin B12. (1976) (10)
- Biogenetic-type synthesis of polyketides. Part X : Synthesis and reactions of hepta and nona-β-carbonyl chains as substrate models (1971) (10)
- Solid state and solution conformation of phenylacetyl-L-cysteinyl-D-penicillamine cyclic disulphide methyl ester; a cyclic dipeptide containing a trans amide (1988) (10)
- Uniformly 13C-enriched substrates as n.m.r probes for metabolic events in vivo. Application of double quantum coherence to a biochemical problem (1982) (10)
- Discovering Nature′s Diverse Pathways to Vitamin B12: A 35‐Year Odyssey. (2003) (10)
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- Eighteen-deoxyaldosterone and other less polar forms of 18-hydroxycorticosterone as aldosterone precursors in rat adrenals. (1985) (9)
- 13C-NMR analysis of alanine metabolism by isolated perfused livers from C3HeB/FeJ mice infected with African trypanosomes. (1988) (9)
- A Simple Algorithm for Superimposing Sets of NMR Derived Structures: Its Application to the Conformational Study of Cephalomannine in Lipophobic and Lipophilic Solution (1996) (9)
- Conversion of cycloocta-1,5-diene-palladium (II) chloride to 6--chloro-2--acetoxybicyclo[3.3.0]Octane by lead tetraacetate in acetic acid (1975) (9)
- Studies On uro'gen III synthase with modified bilanes (1994) (9)
- N.m.r. studies of enzyme mechanism. Comparison of the crystal structure and solid state 13C and 15N n.m.r. spectra of a carboxypeptidase A complex with glycyl tyrosine (1985) (9)
- Biosynthesis of porphyrins and corrins. Direct observation of an enzyme−substrate complex by tritium NMR spectroscopy (1984) (9)
- Biosynthesis of the indole alkaloids: vindoline (1965) (9)
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- The biosynthesis of vitamin B12. (1976) (9)
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- 5-Aminolevulinic acid biosynthesis in Propionibacterium shermanii and Halobacterium salinarium: distribution of the two pathways of 5-aminolevulinic acid biosynthesis in prokaryotes (1993) (9)
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- Evidence for a mono-oxygenase mechanism in the biosynthesis of the fungal tropolones (1972) (8)
- The Early Stages of Papaver Alkaloid Biosynthesis. Cell-Free Synthesis of Benzykisoqui-nolines (1978) (8)
- Template-directed organic synthesis. A model for the peptidyl transfer reaction of protein biosynthesis (1978) (8)
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- Models for Taxol Biosynthesis: SeO2 Oxidation of Taxadiene (2006) (8)
- Recent discoveries in the pathways to cobalamin (coenzyme B12) achieved through chemistry and biology (2007) (8)
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- Chemical aspects of enzyme biotechnology : fundamentals (1990) (8)
- C-AROMATIC COMPOUNDS (1964) (8)
- Mechanism of coenzyme-B12-dependent molecular rearrangements. Evidence for a radical-like process in a model reaction for methylmalonyl–CoA mutase (1980) (8)
- Studies on a synthesis of (RS)-mevalonic acid lactone (1984) (8)
- 794. Oxidative pairing of phenolic radicals. Part II. The synthesis of picrolichenic acid (1961) (8)
- Indole alkaloid biosynthesis in catharanthus roseus — involvement of geissoschizine and 19-epiajmalicine (1979) (8)
- A 13C-n.m.r. investigation of ionizations within a trypsin-inhibitor complex. Evidence that the pKa of histidine-57 is raised by interaction with the hemiketal oxyanion. (1985) (8)
- Synthesis of (±)-(15E)&(15Z)-16-oxa-2,3-oxidosqualenes (1995) (7)
- CONCERNING THE BIOSYNTHESIS OF VITAMIN B12 * (1975) (7)
- β-Caryophyllene Derivatives from the Wild Cottons (1997) (7)
- Asymmetric synthesis of (E)- and (Z)-3,7-dimethyl-2-octene-1,8-diol and callosobruchusic acid (2004) (7)
- ABSOLUTE STEREOCHEMISTRY OF THE BISINDOLE ALKALOIDS OF THE VINBLASTINE TYPE, CIRCULAR DICHROISM STUDIES (1975) (7)
- Vitamin B12: Catalyst for a nonenzymic carbon-skeleton model rearrangement (1980) (7)
- Biosynthesis of vitamin B12. Concerning the mechanism of the uro'gen III → cobyrinic acid transformation (1977) (7)
- Synthesis and biological activity of δ-(L-α-aminoadipoyl)-L-cysteinyl-N-hydroxy-D-valine: a proposed intermediate in the biosynthesis of the penicillins (1984) (7)
- Direct observation of porphyrinogen biosynthesis in living cells by 13C n.m.r. spectroscopy (1979) (6)
- Eudesmane derivatives from Iva frutescens. (1998) (6)
- 771. An alternative synthetic approach to (±)-gibberone (1961) (6)
- Chemoenzymatic synthesis of an unnatural tetramethyl cobalt corphinoid. (1999) (6)
- Recent studies of enzymically controlled steps in B12 biosynthesis. (2007) (6)
- Detection of nascent polyproline II helices in solution by NMR in synthetic insect kinin neuropeptide mimics containing the X-Pro-Pro-X motif. (1999) (6)
- Biogenetic-type synthesis of Iboga alkaloids: (±)-catharanthine (1968) (6)
- Biosynthetic Studies with 13C Labeled Precursors (1976) (6)
- Biosynthesis of the fungal tropolones. Puberulonic and puberulic acids (1972) (6)
- New sesquiterpene alpha-methylene lactones from the Egyptian plant Jasonia candicans. (1993) (6)
- Letter: Biosynthesis of the indole alkaloids. A cell-free system from Catharanthus roseus. (1975) (6)
- The synthesis of 5S-5-[3H1]mevalonic acid lactone (1970) (6)
- Chemical suppression of long range 13C-1H coupling in 13C n.m.r. spectra (1974) (6)
- Biosynthesis of porphyrins and corrins. 1. 1H and 13C NMR spectra of (hydroxymethyl)bilane and uroporphyrinogens I and III. (1986) (6)
- Control of porphyrin biosynthesis in Rhodopseudomonas spheroides and Propionibacterium shermanii. A direct 13C nuclear-magnetic-resonance spectroscopy study. (1981) (6)
- An improved procedure for the synthesis of DL‐[2‐13C]‐glutamic acid (1990) (6)
- HOW NATURE SYNTHESIZES B12 WITHOUT OXYGEN. DISCOVERIES ALONG THE ANCIENT, ANAEROBIC PATHWAY (1998) (6)
- Systematic specificity studies on porphobilinogen deaminase (1994) (6)
- An easy synthesis of (RS)-[3′13C]mevalonic acid lactone (1980) (6)
- Isorosenolic acid, a new diterpenoid constituent of trichothecium roseum link (1964) (6)
- Characterization of the process of 5-aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum. (1991) (5)
- Enzymatic syntheses of 13C-enriched geranylgeranyl diphosphate and casbene from 13C-labeled isopentenyl diphosphate (1998) (5)
- Phenol oxidation. A model for the biosynthesis of the Erythrina alkaloids (1966) (5)
- Vitamin B12. Recent discoveries cast new light on an ancient structure (1996) (5)
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- The chirality of olefin complexes (1969) (5)
- Synthesis of substrate analogs of methyltransferases in the vitamin B(12) biosynthetic pathway and characterization of their enzymatic products. (2006) (5)
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- Synthesis of unsymmetrical dipyrrolyl sulfides (1996) (5)
- Sesquiterpenes produced by truncated taxadiene synthase (2000) (5)
- Intermediates in the vitamin B12 biosynthetic pathway of Propionibacterium shermanii by fast atom bombardment mass spectrometry (1990) (5)
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- NMR studies of biosynthesis and enzyme mechanism (1986) (4)
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- A highly efficient chemoselective synthesis of 3,5-diketoesters by lipase-catalyzed transesterification: application to the resolution of secondary alcohols (2004) (4)
- Photosensitized oxygenation of trans,trans-1-methylcyclodeca-1,6-diene. Regiospecific hydroperoxidation with singlet oxygen (1975) (4)
- Studies on the formation of porphyrinogens from monopyrroles in presence of the enzymes PBG deaminase and/or Uro’gen III synthase (2005) (4)
- B12 biosynthesis: the anaerobic pathway. (1999) (4)
- Fungal metabolites. Part VII. Stereochemistry of gibberellic acid: X-ray analysis of methyl bromogibberellate (1966) (4)
- Intermediary metabolism of cobyrinic acid biosynthesis (1979) (4)
- Retention of configuration at C-3 of (2S,3S)-[4-13C] valine in the biosynthesis of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine, the acyclic precursor of the penicillins (1982) (4)
- O- AND S-HETEROAROMATIC COMPOUNDS (1964) (4)
- Porcine cytosolic aspartate aminotransferase reconstituted with [4'-13C]pyridoxal phosphate. pH- and ligand-induced changes of the coenzyme observed by 13C NMR spectroscopy. (1991) (4)
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- 847. Tropolones. Part VI. Further reactions of tropolone (1952) (3)
- BIOTRANSFORMATION PRODUCTS OF (5R)-(+)-PULEGONE AND (2S, 5R)-(-)-MENTHONE PRODUCED BY CULTURED CELLS OF CATHARANTHUS ROSEUS (1998) (3)
- Rapid separation of cobyrinic acid and its biosynthetic precursors by ion-exchange paper chromatography. (1976) (3)
- Intact incorporation of δ-(α-L-aminoadipoyl)-L-[3-13C]cysteinyl-D-[15N]valine into isopenicillin N. Observation of one-bond 13C–15N coupling (1985) (3)
- Application of the olefin octant rule to some taxane derivatives: assignment of absolute configuration using the Cotton Effect (1970) (3)
- Synthesis of 1-(1-D-car☐y-2-methylpropyl)3-L-(5-L-aminoadipamido)-4-L-mercaptoazetidin-2-one (seco-isopenicillin N), a potential intermediate in penicillin biosynthesis. (1983) (3)
- Epimerization of Taxol® in Human Cancer Cells (1996) (3)
- Photosensitised oxidation of 3β-acetoxylanost-8-ene (1967) (3)
- Design of a reusable enzymatic system for the preparation of porphyrins of biological interest (1994) (3)
- Facile and Highly Selective 5′‐Desilylation of Multisilylated Nucleosides. (2000) (3)
- Tetrapyrrole biosynthesis: N-methyl-N'-nitrosoguanidine-induced mutants of Propionibacterium shermanii. (1976) (3)
- Phenol Oxidation. IV.1Simulation of the Biosynthesis of Colchicine by a Radical-Pairing Reaction of the Tropolone Ring (1963) (3)
- NMR Studies of Biosynthetic Pathways a (1986) (3)
- Biosynthesis of plant products using cell free systems from tissue cultures (1978) (3)
- Studies on the tetramerization of substituted monopyrroles to type I porphyrins (2002) (3)
- Deacetylation of vindoline by buffered cell suspension cultures ofCatharanthus roseus (1990) (3)
- 13C nuclear magnetic resonance observations on the interaction between p-amidinophenylpyruvic acid and trypsin (1985) (3)
- A novel rearrangement of 4-dedimethylamino-4-keto-5a,6-anhydrotetracycline (1975) (3)
- Novel Synthetic Approach to Multibenzoylated Nucleosides (2008) (3)
- How Nature Synthesizes Vitamin B12. A Survey of the Last Four Billion Years (1993) (3)
- Achieving Natural Product Synthesis and Diversity via Catalytic Networking ex vivo (1996) (3)
- NMR studies of the enzyme mechanisms of B12 (1989) (3)
- The synthesis of tetra-acetic acid lactone and a model for the biosynthesis of 6-methylsalicyclic acid (1968) (3)
- Biomimetic self-condensation of malonates mediated by nucleosides. (2007) (3)
- CHIRAL LACTAMS AS TEMPLATES FOR ENZYME INHIBITORS : A SIMPLIFIED ROUTE TO THE EXPANDED POOL (1996) (3)
- Direct syntheses of β‐hydroxyvaline and [4,4′‐2H6]‐β‐hydroxyvaline (1981) (3)
- Unexpected loss of the β-lactam ring during rearrangement of a penicillin sulfoxide (1988) (3)
- BIOSYNTHESE OF CORRINS, A CELL-FREE SYSTEM FROM PROPIONIBACTERIUM SHERMANII (1973) (3)
- Concerning the Intermediacy of Monocyclic b-Lactams in Penicillin Biosynthesis: Synthesis and Attempted Bioconversion of Seco-isopenicillin N (1990) (3)
- Total synthesis of a 15N-labelled macrocyclic tetrapyrrole of the preuroporphyrinogen type (1983) (3)
- On the optical activity of trans-cyclo-octene (1970) (3)
- Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase (2002) (2)
- SOME APPLICATIONS OF SPECTROPHOTOMETRY TO THE ANALYSIS OF NATURAL PRODUCTS (1964) (2)
- Indole Alkaloid Biosynthesis: Partial Purification of "Ajamalicine Synthesis" from Catharanthus roseus Tissue Cultures (1977) (2)
- π–π* Circular dichroism of mono-olefins (1975) (2)
- Applications of NMR and molecular biology in studies of the enzyme mechanisms of vitamin B12 biosynthesis (1989) (2)
- Infrared studies of terpenoid compounds. Part III. Rosololactone and related diterpenoid lactones from Trichothecium roseum link (1966) (2)
- N-HETEROAROMATIC COMPOUNDS (MONO-AZINES) (1964) (2)
- SYNTHESIS OF (+-)-EICOSA-CIS-8,9-(11,12- AND 14,15-) EPOXY-CIS-11,14-(8,14- AND 8,11-) DIENOIC ACIDS AND ATTEMPTED BIOCONVERSION TO PROSTAGLANDINS (1974) (2)
- CARBON‐13 FOURIER TRANSFORM NMR PART 7, STEREOCHEMISTRY OF METHYL GROUP INSERTION IN CORRINOID BIOSYNTHESIS, DETERMINATION OF CARBON ISOTOPE CHIRALITY BY (13)C NUCLEAR MAGNETIC RESONANCE (1973) (2)
- An Improved Transient Method for the Synthesis of N‐Benzoylated Nucleosides. (2003) (2)
- The structure and stereochemistry of hirsutic acid C, a novel fungal sesquiterpenoid (1965) (2)
- Synthesis of Chiral Lactams as Templates for Enzyme Inhibitors: An Unusual Annulation in the Intramolecular Wadsworth-Horner-Emmons Reaction (1994) (2)
- Synthesis of ?-(L-?-aminoadipyl)-L-cysteinyl-D-valine and ?-(L-?-aminoadipyl)-L-cysteinyl-D-valylglycine (1983) (2)
- Towards the genetically engineered synthesis of natural products (1994) (2)
- Use of fluoroptic thermometer temperature sensing for high-resolution temperature-controlled NMR applications (1988) (2)
- 888. The self-condensation of cyclodecane-1 : 2-dione (1952) (2)
- Autoxidation of pyrrolylurethanes (1997) (2)
- Determination of absolute configuration of platinum–olefin complexes by circular dichroism (1968) (2)
- Synthesis and aromatisation of the linear hepta-β-carbonyl system (1968) (2)
- 19-Bromo-1-hydroxymethylbilane, a novel inhibitor of uro'gen III synthase. (1994) (2)
- Laboratory Models for the Biogenesis of Indole Alkaloids (1975) (1)
- Preparation of two stereochemically defined isomers of deuterium labeled δ‐cadinene (1997) (1)
- APPLICATION OF 13C-NMR SPECTROSCOPY IN THE STUDY OF METABOLISM IN VIVO AND IN VITRO (1981) (1)
- 1H and 13C NMR studies of sirohydrochlorin (factor II) and its 20-methyl derivative (factor III) (1992) (1)
- Selective 13C-edited 1D NOESY spectroscopy in proteins using a heteronuclear Half-Gaussian pulse (1990) (1)
- Preparation of a mono hemi-ketal of a thiosulfonate ester (1975) (1)
- A General Synthesis of β-Aryl and Heteroarylpyrroles by Palladium- Catalyzed Coupling Reaction of β-Tributylstannylpyrrole with Aryl and Heteroaryl Halides. (1996) (1)
- Self-Condensation of Activated Malonic Acid Half Esters: A Model for the Decarboxylative Claisen Condensation in Polyketide Biosynthesis. (2004) (1)
- Synthesis of novel 19-(alkyloxycarbonylamino)bilanes (1999) (1)
- Regio- and stereospecific models for the biosynthesis of the indole alkaloids. Prologue and commentary. (1972) (1)
- STRUCTURE AND ABSOLUTE CONFIGURATION OF (+)-CORONARIDINE HYDROBROMIDE, A COMMENT ON THE ABSOLUTE CONFIGURATION OF THE IBOGA ALKALOIDS (1973) (1)
- CHAPTER 1 – SINGLE CHROMOPHORES (1964) (1)
- CONCERNING THE INTERMEDIACY OF URO′GEN III AND OF A HEPTACARBOXYLIC URO′GEN IN CORRINOID BIOSYNTHESIS (1975) (1)
- 4.06 – Enzymatically Controlled Steps in Vitamin B12 Biosynthesis (1999) (1)
- A Convenient Synthesis of 2‐(Diethoxyphosphonyl)glycine and Its Derivatives. (1993) (1)
- Circular dichroism of platinum–olefin complexes (1967) (1)
- Biosynthesis of corrinoids. Uroporphyrinogen 3 as a precrusor of vitamin B 12 . (1972) (1)
- Crystal and molecular structure of a proline derivative: t-butyl-(E)-5-p-nitrobenzyloxycarbonylmethine-L-proline (1994) (1)
- An efficient synthesis of δ-amino[3-13C]levulinic acid (2002) (1)
- Simple devices for sterile aeration and mixing in NMR cell metabolism studies (1991) (1)
- Preparation of Aminated Taxol Side Chain Precursors. A Simple Approach to 2,3‐Diamino Acids Using the β‐Lactam Synthon Method. (1997) (1)
- CONVERSION OF CYCLOOCTA-1,5-DIENE-PALLADIUM(II) CHLORIDE TO 6-EXO-CHLORO-2-ENDOACETOXYBICYCLO(3,3,0)OCTANE BY LEAD TETRAACETATE IN ACETIC ACID (1975) (1)
- Structure–function studies on an S-adenosyl-l-methionine dependent uroporphyrinogen-III C-methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis (2004) (1)
- An Improved Procedure for the Epoxidation of Methyl Cinnamate Derivatives and Production of Acid Sensitive Epoxides. (1996) (1)
- Chapter 3 The biosynthesis of vitamin B12 (1991) (1)
- PHOTOSENSITIZED OXYGENATION OF TRANS, TRANS-1-METHYLCYCLODECA-1,6-DIENE. A REGIOSPECIFIC HYDROPEROXIDATION WITH SINGLET OXYGEN (1975) (1)
- Synthesis of [4′‐13C] pyridoxol (1985) (1)
- Erratum: Synthesis and characterization of Cu(1) complex compounds with methyl isonicotinate (1977) (0)
- Aqueous Trichloroacetic Acid: Another Useful Reagent for Highly Selective 5′-Desilylation of Multisilylated Nucleosides. (2003) (0)
- Applications of NMR and Molecular Biology in Studies of the Enzyme Mechanism of Vitamin B12 Biosynthesis (1989) (0)
- THE STRUCTURE OF FACTOR III: A TRIMETHYL ISOBACTERIOCHLORIN INTERMEDIATE IN THE BIOSYNTHESIS OF VITAMIN B12††Dedicated to the memory of Prof. R. B. Woodward. (1981) (0)
- SYNTHESIS OF 1-(1-D-CARBOXY-2-METHYLPROPYL)-3-L-(5-L-AMINOADIPAMIDO)-4-L-MERCAPTOAZETIDIN-2-ONE (SECOISOPENICILLIN N), A POTENTIAL INTERMEDIATE IN PENICILLIN BIOSYNTHESIS (1983) (0)
- Additions and Corrections - Concerning the Intermediacy of Uro'gen III and of a Heptacarboxylic Uro'Gen in Corrinoid Biosynthesis (1976) (0)
- The Bakerian Lecture (1996): Genetically Engineered Synthesis of Natural Products (1998) (0)
- Structure of Factor S3, a Metabolite of Propionibacterium shermanii Derived from Uroporphyrinogen I. (1987) (0)
- Synthesis of a Novel Tetrapyrrolic Macrolactam (X) and Its Activity Towards Uro′gen III Synthase. (1996) (0)
- Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT (2004) (0)
- Study of the Cotton effect of 16-substituted 20-keto pregnane and 17-alpha-pregnane derivatives. (1964) (0)
- RECENT PROGRESS IN THE SEARCH FOR BIOSYNTHETIC INTERMEDIATES (1971) (0)
- Unexpected Loss of the β-Lactam Ring During Rearrangement of a Penicillin Sulfoxide. (1988) (0)
- Mechanism of emodin deoxygenation to chrysophanol (1988) (0)
- Characterization of parasite metabolism by 13 CNMR spectroscopy (1988) (0)
- Synthesis of (.+‐.)‐(15E) and (15Z)‐16‐Oxa‐2,3‐oxidosqualenes (1995) (0)
- Synthesis and reactions of alpha-thioformyl dipeptides, possible biogenetic precursors of penicillin. (1974) (0)
- An Improved Synthesis of the Dinucleotides pdCpA and pdCpdA. (2001) (0)
- Synthesis of a novel tetrapyrrolic macrolactam and its activity towards Uro'gen III synthase† (2010) (0)
- Enzymatic Transformations: Isotope Probes (2007) (0)
- Applications of NMR in Biochemistry and Biosynthesis (1988) (0)
- Synthesis and Biological Activity of δ-(L-α-Amino-adipoylyl)-L-cysteinyl-N-hydroxy-D-valine: A Proposed Intermediate in the Biosynthesis of the Penicillins. (1984) (0)
- Synthesis of Oxa Analogues of Porphobilinogen (PBG) as Probes for Mechanistic Studies of PBG Deaminase. (2010) (0)
- SYNTHESIS AND REACTIONS OF THIOALDEHYDE DEHYDROPEPTIDES RELATED TO BETA-LACTAM ANTIBIOTICS (1974) (0)
- ChemInform Abstract: Reflections on the Discovery of Nature′s Pathways to Vitamin B12 (2002) (0)
- Synthesis of Chiral Lactams as Templates for Enzyme Inhibitors: An Unusual Annulation in the Intramolecular Wadsworth-Horner-Emmons Reaction. (1994) (0)
- CRYSTAL STRUCTURE ANALYSIS OF PRECORRIN-8X METHYLMUTASE COMPLEX WITH HYDROGENOBYRINIC ACID (2001) (0)
- STRUCTURE AND BIOGENETIC-TYPE SYNTHESIS OF ANDRANGININE, AN INDOLE ALKALOID OF A NEW TYPE (1974) (0)
- NMR Studies of the Enzyme Mechanisms of Vitamin B12 Biosynthesis (1991) (0)
- Erratum: Concerning the intermediacy of uro'gen III and of a heptacarboxylic uro'gen in corrinoid biosynthesis (Journal of the American Chemical Society (1975) 97 (2548)) (1976) (0)
- Uroporphyrinogen III methylase catalyzes the enzymic synthesis of sirohydrochlorins II and IV by a clockwise mechanism [Erratum to document cited in CA113(3):20050w] (1990) (0)
- Synthesis of the 2‐Fluoro‐11‐hydroxy Analogue of Porphobilinogen, a New Suicide Inhibitor of the Enzyme Porphobilinogen Deaminase. (1994) (0)
- SYNTHESIS OF Δ-(L-α-AMINOADIPYL)-L-CYSTEINYL-D-VALINE AND Δ-(L-α-AMINOADIPYL)-L-CYSTEINYL-D-VALYLGLYCINE (1983) (0)
- Solid State and Solution Conformation of Phenylacetyl-L-Cysteinyl-D-penicillamine Cyclic Disulfide Methyl Ester: A Cyclic Dipeptide Containing a trans Amide. (1988) (0)
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- Porphyrins Switch Mechanism Clarified. (1976) (0)
- Discovery of Nature′s Pathway to Vitamin B12. A 25 Year Odyssey (1995) (0)
- Factor S1, a Natural Corphin from Propionibacterium shermanii. (1988) (0)
- CorrigendumA convenient synthesisof 2-(diethoxyphosphonyl)glycine and its derivatives (1994) (0)
- MINIREVIEW Fine-Tuning Our Knowledge of the Anaerobic Route to Cobalamin (Vitamin B 12 ) (cid:1) (2006) (0)
- Mechanism-based inactivation of porphobilinogen synthase: Substitution of ketone functionality in the substrate with a thioester (1995) (0)
- An Efficient Synthesis of 4(5),11(12)-Taxadiene Derivatives and Microbial Mediated 20-Hydroxylation of Taxoids. (2000) (0)
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- How Nature Sunthesizes Vitamin B 12 . A Survey of the Last Four Billion Years (2002) (0)
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- Regio- and sterospecific models for the biosynthesis of the indole alkaloids. The Aspidosperma-Iboga relationship. (1972) (0)
- REACTIVITY OF PEPTIDE HYDROXAMATES. A MODEL FOR THE BIOSYNTHESIS OF β-LACTAM ANTIBIOTICS (1976) (0)
- An Efficient Synthesis of 3-Vinylpyrroles by Stille Coupling Reaction of 3-Iodopyrroles with Vinyltributyltin. (1996) (0)
- Preparation of Pyrrolin-2-ones and 4,5-Dihydrodipyrrin-1-ones by Oxidation of α-Formylpyrroles and α-Formyldipyrromethanes with Hydrogen Peroxide. (2000) (0)
- Applications of 13C nmr in the study of biosynthetic mechanism. (1985) (0)
- CRYSTAL STRUCTURE ANALYSIS OF PRECORRIN-8X METHYLMUTASE OF AEROBIC VITAMIN B12 SYNTHESIS (2001) (0)
- Regio- and stereospecif models for the biosynthesis of the indole alkaloids. The Corynanthe-Strychnoslboga relationship. (1972) (0)
- INTACT INCORPORATION OF Δ-(α-L-AMINOADIPOYL)-L-CYSTEINYL-3-13C-D-VALINE-15N INTO ISOPENICILLIN N. OBSERVATION OF ONE-BOND CARBON-13-NITROGEN-15 COUPLING (1985) (0)
- Fluorination of Pyrrolic Compounds with Xenon Difluoride. (1994) (0)
- SYMMETRIEREGEL FUER CHIRALE OLEFINE (1970) (0)
- Regio- and stereospecific models for the biosynthesis of the indole alkaloids. The Corynanthe-Aspidosperma relationship. (1972) (0)
- Letter: Absolute stereochemistry of the bisindole alkaloids of the vinblastine type. Circular dichroism studies. (1975) (0)
- Biosynthesis of vitamin B12: Facl anaerobic pathway (tetradehydrocorrin/biosynthetic intermediate/NMR spectroscl (1996) (0)
- Biosynthesis of vitamin B12: Con two-carbon fragment eliminated formation of cobyrinic acid (acetaldehyde/l3C-NMR spectroscopy/Propionibacterium shermi (1996) (0)
- Visualization of vacuoplasts in isolated vacuole preparations from mesophyll protoplasts of periwinkle [Catharanthus roseus (L.) G. Don] (1992) (0)
- THE STRUCTURE OF THE ANTIBIOTIC HEDAMYCIN. I. CHEMICAL, PHYSICAL AND SPECTRAL L PROPERTIES (1977) (0)
- BIOSYNTHESIS OF PORPHYRINS AND CORRINS. DIRECT OBSERVATION OF AN ENZYME-SUBSTRATE COMPLEX BY TRITIUM NMR SPECTROSCOPY (1985) (0)
- Fluoro-Decarboxylation of Pyrrolecarboxylic Acids by F-TEDA-BF4 - A Convenient General Synthesis of Fluoropyrroles. (1996) (0)
- N-HETEROAROMATIC COMPOUNDS (POLYAZINES) (1964) (0)
- Concerning the Intermediacy of Monocyclic β‐Lactams in Penicillin Biosynthesis: Synthesis and Attempted Bioconversion of Seco‐isopenicillin N. (1990) (0)
- Additions and Corrections - Biosynthesis of Indole Alkaloids. Vindoline. (1969) (0)
- NMR studies of the enzyme mechanisms of BI2 b iosy n t hesis (1989) (0)
- Scott, A. Ian: 13C NMR Studies of Biosynthesis. A Quarter Century in Retrospect (2007) (0)
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