Ikuo Morita
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Philosophy Biology
Ikuo Morita's Degrees
- PhD Molecular Biology University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Ikuo Morita's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Autoamplification of NFATc1 expression determines its essential role in bone homeostasis (2005) (771)
- Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2 (*) (1995) (608)
- Biocompatible inkjet printing technique for designed seeding of individual living cells. (2005) (494)
- Distinct functions of COX-1 and COX-2. (2002) (432)
- IL-6 increases endothelial permeability in vitro. (1992) (387)
- Novel mechanism for age‐related macular degeneration: An equilibrium shift between the angiogenesis factors VEGF and PEDF (2001) (267)
- TGF-β regulates isoform switching of FGF receptors and epithelial–mesenchymal transition (2011) (208)
- Contribution of Nuclear Factor of Activated T Cells c1 to the Transcriptional Control of Immunoreceptor Osteoclast-associated Receptor but Not Triggering Receptor Expressed by Myeloid Cells-2 during Osteoclastogenesis* (2005) (200)
- The potential role of amyloid beta in the pathogenesis of age-related macular degeneration. (2005) (195)
- Prostaglandins promote osteoclastlike cell formation by a mechanism involving cyclic adenosine 3′,5′‐monophosphate in mouse bone marrow cell cultures (1989) (193)
- The Gap Junction-independent Tumor-suppressing Effect of Connexin 43* (2003) (177)
- Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro. (1988) (176)
- Topographic analyses of shape of eyes with pathologic myopia by high-resolution three-dimensional magnetic resonance imaging. (2011) (176)
- The inhibitory effect of vitamin K2 (menatetrenone) on bone resorption may be related to its side chain. (1995) (174)
- A comparison of the tube forming potentials of early and late endothelial progenitor cells. (2008) (158)
- Sonic Hedgehog Signaling is Important in Tooth Root Development (2006) (154)
- Stimulatory effects of insulin and insulin-like growth factor I on migration and tube formation by vascular endothelial cells. (1992) (154)
- Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell. (1993) (134)
- Participation of oxidative stress in the process of osteoclast differentiation. (1993) (129)
- A novel route for connexin 43 to inhibit cell proliferation: negative regulation of S-phase kinase-associated protein (Skp 2). (2003) (127)
- Connexin43 suppresses proliferation of osteosarcoma U2OS cells through post-transcriptional regulation of p27 (2001) (122)
- Isolation of multipotent stem cells from adult rat periodontal ligament by neurosphere-forming culture system. (2007) (121)
- Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis (2017) (121)
- Regulation of bone morphogenetic protein‐2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells (2004) (117)
- Eicosapentaenoic acid inhibits bone loss due to ovariectomy in rats. (1994) (115)
- Growth/differentiation factor-5 induces angiogenesis in vivo. (1997) (113)
- Conditioned Medium from Periodontal Ligament Stem Cells Enhances Periodontal Regeneration. (2016) (105)
- Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons (2003) (102)
- Effect of eicosapentaenoic acid on the platelet aggregation and composition of fatty acid in man. A double blind study. (1983) (102)
- Protein kinase CK2 is a key activator of histone deacetylase in hypoxia‐associated tumors (2008) (100)
- Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells. (2003) (95)
- Docosapentaenoic acid (22:5, n-3) suppressed tube-forming activity in endothelial cells induced by vascular endothelial growth factor. (2003) (92)
- Amyloid‐β up‐regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age‐related macular degeneration (2009) (91)
- Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells (1990) (90)
- Reduced retinal angiogenesis in MMP-2-deficient mice. (2003) (89)
- Effect of vitamin K2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures. (1994) (84)
- Cementum protein 1 (CEMP1) induces a cementoblastic phenotype and reduces osteoblastic differentiation in periodontal ligament cells (2012) (84)
- Altered Function of Factor I Caused by Amyloid β: Implication for Pathogenesis of Age-Related Macular Degeneration from Drusen1 (2008) (83)
- Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. (1983) (82)
- Different substrate utilization between prostaglandin endoperoxide H synthase-1 and -2 in NIH3T3 fibroblasts. (1998) (79)
- Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes. (2009) (78)
- Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol‐3 kinase/Akt pathway (2000) (78)
- Eicosapentaenoic acid attenuates vascular endothelial growth factor‐induced proliferation via inhibiting Flk‐1 receptor expression in bovine carotid artery endothelial cells (1998) (73)
- Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat. (1989) (73)
- Involvement of adhesion molecules LFA-1 and ICAM-1 in osteoclast development. (1993) (72)
- High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization. (1999) (70)
- Expression of estrogen receptors in a normal human breast epithelial cell type with luminal and stem cell characteristics and its neoplastically transformed cell lines. (1997) (68)
- Periodontal ligament stem cells possess the characteristics of pericytes. (2013) (68)
- Docosapentaenoic acid (22:5, n-3), an elongation metabolite of eicosapentaenoic acid (20:5, n-3), is a potent stimulator of endothelial cell migration on pretreatment in vitro. (1996) (68)
- The effects of amniotic membrane on retinal pigment epithelial cell differentiation. (2005) (67)
- Mechanical stress induces production of angiogenic regulators in cultured human gingival and periodontal ligament fibroblasts. (2003) (67)
- Cerebellar nitric oxide synthase activity is reduced in nervous and Purkinje cell degeneration mutants but not in climbing fiber-lesioned mice (1993) (66)
- The Control of Vascular Endothelial Cell Injury (1990) (65)
- C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase. (2007) (65)
- Leukotriene C4 stimulates angiogenesis in bovine carotid artery endothelial cells in vitro. (1989) (63)
- Periodontal regeneration using periodontal ligament stem cell-transferred amnion. (2013) (62)
- Quantitative analyses of high-resolution 3D MR images of highly myopic eyes to determine their shapes. (2012) (61)
- Direct integration of cell‐free‐synthesized connexin‐43 into liposomes and hemichannel formation (2010) (61)
- Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene. (2003) (59)
- A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol. (1997) (57)
- Expression and function of PPARγ in rat placental development (2004) (57)
- Supplementation of arachidonic acid-enriched oil increases arachidonic acid contents in plasma phospholipids, but does not increase their metabolites and clinical parameters in Japanese healthy elderly individuals: a randomized controlled study (2011) (55)
- Expression of IL-6 receptor and GP130 in mouse bone marrow cells during osteoclast differentiation. (1998) (55)
- Prostaglandin production via induction of cyclooxygenase-2 by human gingival fibroblasts stimulated with lipopolysaccharides (1996) (55)
- Arachidonic-acid metabolism in normal and experimentally-inflamed rat dental pulp. (1987) (54)
- Inhibition of angiogenesis by staurosporine, a potent protein kinase inhibitor. (1992) (52)
- Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels (1994) (51)
- Eponemycin, a novel antibiotic, is a highly powerful angiogenesis inhibitor. (1991) (51)
- Cytoprotective effect of reduced glutathione in arsenical-induced endothelial cell injury. (1991) (51)
- Involvement of prostaglandin endoperoxide H synthase‐2 in osteoclast‐like cell formation induced by interleukin‐1β (1996) (50)
- Increased arachidonic acid content in platelet phospholipids from diabetic patients. (1983) (50)
- A possible mechanism for vascular endothelial cell injury elicited by activated leukocytes: a significant involvement of adhesion molecules, CD11/CD18, and ICAM-1. (1994) (49)
- Conversion of xanthine dehydrogenase to xanthine oxidase in bovine carotid artery endothelial cells induced by activated neutrophils: involvement of adhesion molecules. (1995) (49)
- Involvement of the collagen I-binding motif in the anti-angiogenic activity of pigment epithelium-derived factor. (2005) (48)
- Enhancement of membrane fluidity in cholesterol-poor endothelial cells pre-treated with simvastatin. (1997) (48)
- Re‐expression of functional P‐selectin molecules on the endothelial cell surface by repeated stimulation with thrombin (1997) (48)
- Radicicol, a microbial cell differentiation modulator, inhibits in vivo angiogenesis. (1993) (47)
- Connexin 43 expression promotes malignancy of HuH7 hepatocellular carcinoma cells via the inhibition of cell-cell communication. (2007) (47)
- Nuclear disintegration as a leading step of glutamate excitotoxicity in brain neurons (1996) (46)
- Three novel synthetic retinoids, Re 80, Am 580 and Am 80, all exhibit anti-angiogenic activity in vivo. (1993) (46)
- The effects of polyunsaturated fatty acids and their metabolites on osteoclastogenesis in vitro. (2010) (46)
- Prostaglandin-synthesizing system in rat liver. (1978) (45)
- The role of Mac‐1 (CD11b/CD18) in osteoclast differentiation induced by receptor activator of nuclear factor‐κB ligand (2008) (43)
- The detection of platelet-activating factor in inflamed human gingival tissue. (1989) (43)
- Three isoforms of platelet-derived growth factors all have the capability to induce angiogenesis in vivo. (1994) (43)
- Effects of eicosapentaenoic acid on arachidonic acid metabolism in cultured vascular cells and platelets: species difference. (1983) (42)
- Roles of glutathione and glutathione peroxidase in the protection against endothelial cell injury induced by 15-hydroperoxyeicosatetraenoic acid. (1992) (40)
- Expression and role of mannose receptor/terminal high-mannose type oligosaccharide on osteoclast precursors during osteoclast formation. (2003) (40)
- In vitro formation of capillary networks using optical lithographic techniques. (2007) (39)
- Regulation of Angiogenesis by Controlling VEGF Receptor (2000) (39)
- Presence of nitric oxide synthase activity in the neurons of the rat embryonal cerebrum (1991) (39)
- Cadmium stimulates prostaglandin E2 production and bone resorption in cultured fetal mouse calvaria. (1989) (38)
- Placenta Mesenchymal Stem Cell Derived Exosomes Confer Plasticity on Fibroblasts (2016) (38)
- Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin A4 contents in colon, but does not affect severity or prostaglandin E2 content in murine colitis model (2014) (37)
- Mechanism for endothelial cell injury induced by 15-hydroperoxyeicosatetraenoic acid, an arachidonate lipoxygenase product. (1992) (36)
- Induction of KDR expression in bovine arterial endothelial cells by thrombin: Involvement of nitric oxide (2002) (36)
- Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid β in age-related macular degeneration. (2012) (36)
- Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model (2015) (36)
- Effects of glucose on migration, proliferation and tube formation by vascular endothelial cells (1991) (36)
- Appearance of the arachidonic acid metabolic pathway in human promyelocytic leukemia (HL-60) cells during monocytic differentiation: enhancement of thromboxane synthesis by 1 alpha,25-dihydroxyvitamin D-3. (1986) (35)
- Inhibition of PGE2 production in macrophages from vitamin E-treated rats. (1991) (35)
- Eicosapentaenoic acid inhibits tube formation of vascular endothelial cellsin vitro (1991) (35)
- Expression and function of PPARgamma in rat placental development. (2004) (34)
- Transcriptome Remodeling in Hypoxic Inflammation (2010) (34)
- Promotion of osteoclast differentiation and activation in spite of impeded osteoblast-lineage differentiation under acidosis: effects of acidosis on bone metabolism. (2013) (34)
- Preventive effect of zinc against cadmium-induced bone resorption. (1990) (33)
- Relationship between the ability to support differentiation of osteoclast-like cells and adipogenesis in murine stromal cells derived from bone marrow. (2000) (33)
- Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. (2000) (33)
- Expression on outer membranes of mannose residues, which are involved in osteoclast formation via cellular fusion events. (1994) (33)
- The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. (1977) (32)
- Connexin 43 contributes to differentiation of retinal pigment epithelial cells via cyclic AMP signaling. (2008) (32)
- Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation (2008) (32)
- Expression of angiogenesis‐related factors and inflammatory cytokines in placenta and umbilical vessels in pregnancies with preeclampsia and chorioamnionitis/funisitis (2012) (32)
- Screening of anti-hypoxia/reoxygenation agents by an in vitro method. Part 2: Inhibition of tyrosine kinase activation prevented hypoxia/reoxygenation-induced injury in endothelial gap junctional intercellular communication. (2000) (32)
- Involvement of cholesterol in osteoclast-like cell formation via cellular fusion. (1998) (32)
- The Fate of Transplanted Periodontal Ligament Stem Cells in Surgically Created Periodontal Defects in Rats (2019) (32)
- Augmentation of endothelin-1, prostacyclin and thromboxane A2 secretion associated with in vitro ageing in cultured human umbilical vein endothelial cells (1993) (32)
- Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-α cytotoxicity (2001) (31)
- Pretreatment with eicosapentaenoic acid prevented hypoxia/reoxygenation-induced abnormality in endothelial gap junctional intercellular communication through inhibiting the tyrosine kinase activity. (1999) (31)
- PGE2 induces its own secretion in vitro by bovine 270-day placenta but not by 200-day placenta. (1999) (31)
- In vitro and in vivo characterization of iris pigment epithelial cells cultured on amniotic membranes. (2006) (30)
- Vitamin K2 and geranylgeraniol, its side chain component, inhibited osteoclast formation in a different manner. (2004) (30)
- Arachidonic acid metabolism in cultured astrocytes from rat embryo and in C6 glioma cells (1989) (29)
- Involvement of tyrosine kinase in the hypoxia/reoxygenation‐induced gap junctional intercellular communication abnormality in cultured human umbilical vein endothelial cells (1999) (29)
- Endogenous nitric oxide blocks calcium influx induced by glutamate in neurons containing NADPH diaphorase (1993) (29)
- Potential enhancement of osteoclastogenesis by severe acute respiratory syndrome coronavirus 3a/X1 protein (2009) (29)
- POSSIBLE INVOLVEMENT OF A CHLORIDE—BICARBONATE EXCHANGER IN APOPTOSIS OF ENDOTHELIAL CELLS AND CARDIOMYOCYTES (1999) (29)
- The role of the Cx43 C-terminus in GJ plaque formation and internalization. (2012) (29)
- Effects of purified eicosapentaenoic acid on arachidonic acid metabolism in cultured murine aortic smooth muscle cells, vessel walls and platelets (2006) (28)
- A new in vitro method using fura-2 for the quantification of endothelial cell injury. (1988) (28)
- Communication-dependent mineralization of osteoblasts via gap junctions. (2014) (28)
- The steady-state expression of connexin43 is maintained by the PI3K/Akt in osteoblasts. (2009) (28)
- Involvement of adhesion molecules (CD11a-ICAM-1) in vascular endothelial cell injury elicited by PMA-stimulated neutrophils. (1991) (27)
- Human oral squamous cell carcinoma cell lines promote angiogenesis via expression of vascular endothelial growth factor and upregulation of KDR/flk-1 expression in endothelial cells. (2000) (27)
- Basolateral BMP Signaling in Polarized Epithelial Cells (2013) (27)
- Recruitment of bone marrow-derived cells to periodontal tissue defects (2014) (27)
- Expression-activity profiles of cells transfected with prostaglandin endoperoxide H synthase measured by quantitative fluorescence microscopy. (1995) (27)
- Regulation of chemokine gene expression by hypoxia via cooperative activation of NF-kappaB and histone deacetylase. (2009) (26)
- Amlodipine Modulates THP-1 Cell Adhesion to Vascular Endothelium via Inhibition of Protein Kinase C Signal Transduction (2003) (26)
- Prostaglandin D2 is the major prostaglandin of arachidonic acid metabolism in rat bone marrow homogenate. (1980) (25)
- Constitutive Expression and Involvement of Cyclooxygenase-2 in Human Megakaryocytopoiesis (2004) (25)
- Human uterine myometrial smooth muscle cell proliferation and vascular endothelial growth-factor production in response to platelet-derived growth factor. (2001) (25)
- Inhibitory effects of interleukin 6 on prostaglandin I2 production in cultured bovine vascular endothelial cells. (1992) (25)
- Change in prostaglandin E synthases (PGESs) in microsomal PGES-1 knockout mice in a preterm delivery model. (2005) (24)
- Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1β in human synovial fibroblasts (2003) (24)
- Acidosis environment promotes osteoclast formation by acting on the last phase of preosteoclast differentiation: a study to elucidate the action points of acidosis and search for putative target molecules. (2011) (23)
- Cadmium stimulates prostaglandin E2 synthesis in osteoblast-like cells, MC3T3-E1. (1989) (23)
- Preparation of connexin43‐integrated giant Liposomes by a baculovirus expression–liposome fusion method (2010) (23)
- Ipriflavone inhibits murine osteoclast formationIn Vitro (2005) (23)
- Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. (1978) (22)
- Prolonged exposure to high glucose impaired cellular behavior of normal human corneal epithelial cells (2003) (22)
- Inhibitory effect of docosahexaenoic acid-containing phospholipids on 5-lipoxygenase in rat basophilic leukemia cells. (1993) (22)
- The Role of Leukotriene B4 in Neutrophil Infiltration in Experimentally-induced Inflammation of Rat Tooth Pulp (1991) (21)
- Neuroprotective effects of human umbilical cord-derived mesenchymal stem cells on periventricular leukomalacia-like brain injury in neonatal rats (2017) (21)
- PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. (2007) (21)
- Pathophysiological roles of arachidonic acid metabolites in rat dental pulp. (1992) (20)
- Transforming growth factor-β stimulates IL-1β-induced monocyte chemoattractant protein-1 expression in human synovial cells via the ERK/AP-1 pathway (2006) (20)
- Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment. (2015) (20)
- Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. (2010) (20)
- Cell adhesion molecule mediates endothelial cell injury caused by activated neutrophils. (1996) (19)
- Astrocytes are responsive to endothelium-derived relaxing factor (EDRF) (1991) (19)
- Regulation of the expression of pigment epithelium-derived factor, an anti-angiogenic factor in human oral squamous cell carcinoma cell lines. (2003) (19)
- Enhancement of migration in bovine endothelial cells by eicosapentaenoic acid pretreatment. (1991) (19)
- The involvement of DNA and histone methylation in the repression of IL-1β-induced MCP-1 production by hypoxia. (2011) (19)
- Inhibitory effects of eicosapentaenoic acid (EPA) on the hypoxia/reoxygenation-induced tyrosine kinase activation in cultured human umbilical vein endothelial cells. (2002) (19)
- Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra (1994) (19)
- Regulation of platelet aggregation and arachidonate metabolism in streptozotocin-diabetic rats. (1986) (19)
- Cholesterol enhances amyloid β deposition in mouse retina by modulating the activities of Aβ-regulating enzymes in retinal pigment epithelial cells. (2012) (19)
- Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. (2001) (19)
- Hypoxia-reoxygenation inhibits gap junctional communication in cultured human umbilical vein endothelial cells. (2000) (19)
- Therapeutic Angiogenesis by Implantation of a Capillary Structure Constituted of Human Adipose Tissue Microvascular Endothelial Cells (2010) (18)
- Platelet thromboxane synthesizing activity in non-insulin-dependent diabetes: correlation with diabetic retinopathy and diabetic treatment. (1985) (18)
- Establishment of novel therapy to reduce progression of myopia in rats with experimental myopia by fibroblast transplantation on sclera (2018) (18)
- Increased bone mass in adult prostacyclin-deficient mice. (2010) (17)
- Impact of Docosahexaenoic Acid on Gene Expression during Osteoclastogenesis in Vitro—A Comprehensive Analysis (2013) (17)
- Chemical ionization mass spectrometry of trimethylsilyl derivatives of various prostaglandins. (1978) (17)
- Increased prostacyclin synthesizing activity in human ripening uterine cervix. (1981) (17)
- Immunohistochemical detection of prostaglandin I2 synthase in various calcified tissue-forming cells in rat. (1993) (16)
- Vitamin K2 (menatetrenone) induces iNOS in bovine vascular smooth muscle cells: no relationship between nitric oxide production and gamma-carboxylation. (1999) (16)
- Expression of adhesion molecules LFA-I and ICAM-I on osteoclast precursors during osteoclast differentiation and involvement of estrogen deficiency (2000) (16)
- Preventive effects of zinc on cadmium-induced inhibition of alkaline phosphatase activity and mineralization activity in osteoblast-like cells, MC3T3-E1. (1989) (16)
- Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1β in human synovial fibroblasts (2004) (16)
- Effect of 15‐deoxyspergualin, a microbial angiogenesis inhibitor, on the biological activities of bovine vascular endothelial cells (1992) (16)
- Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages. (1978) (16)
- Phenotypic change regulates monocyte chemoattractant protein‐1 (MCP‐1) gene expression in human retinal pigment epithelial cells (2003) (16)
- Prostaglandin-synthesizing system in rat liver: changes with aging and various stimuli. (1980) (15)
- Cell‐printing and transfer technology applications for bone defects in mice (2011) (15)
- Prostaglandin-synthesizing system in rat liver homogenates: ATP shifts arachidonic acid away from cyclooxygenase into phospholipids. (1980) (15)
- Vitamin K2 suppresses malignancy of HuH7 hepatoma cells via inhibition of connexin 43. (2008) (15)
- Involvement of nitric oxide and free radical (O2-) in neuronal injury induced by deprivation of oxygen and glucose in vitro. (1994) (15)
- Changes in characteristics of periodontal ligament stem cells in spheroid culture. (2018) (15)
- Double-layered cell transfer technology for bone regeneration (2016) (15)
- Inhibition of vacuolar‐type (H+)‐ATPase by the cytostatic macrolide apicularen A and its role in apicularen A‐induced apoptosis in RAW 264.7 cells (2006) (14)
- The existence of distinct classes of prostaglandin E2 receptors mediating adenylate cyclase and phospholipase C pathways in osteoblastic clone MC3T3-E1. (1992) (14)
- Adhesion Molecule Mediated Endothelial Cell Injury Elicited by Activated Leukocytes a (1994) (14)
- Expression and possible role of PVR/CD155/Necl-5 in osteoclastogenesis (2007) (14)
- Effects of nitrogen dioxide exposure on prostacyclin synthesis in lung and thromboxane A2 synthesis in platelets in rats. (1983) (14)
- A narrow window for rescuing cells by the inhibition of calcium influx and the importance of influx route in rat cortical neuronal cell death induced by glutamate (2001) (14)
- Pharmacological characterization of cepharanthin in chronic idiopathic thrombocytopenic purpura (2001) (13)
- Effect of various prostaglandins on the release of arachidonic acid from cultured fibroblasts. (1978) (13)
- Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast formation induced by parathyroid hormone. (1997) (13)
- Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation. (1994) (13)
- Simvastatin, a potent HMG-CoA reductase inhibitor, inhibits the proliferation of human and bovine endothelial cells in vitro. (1998) (13)
- Rubratoxin B induces apoptosis in p53-null cells (1998) (13)
- Implantation of capillary structure engineered by optical lithography improves hind limb ischemia in mice. (2010) (13)
- A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. (1999) (12)
- Tumor associated osteoclast-like giant cells promote tumor growth and lymphangiogenesis by secreting vascular endothelial growth factor-C. (2014) (12)
- Effect of IL-6 on tumor cell invasion of vascular endothelial monolayers (1997) (12)
- Characterization of the stimulatory effects of PGF2alpha on the release of arachidonic acid. (1979) (12)
- Enhancement of migration activity in cholesterol-poor endothelial cells by pre-treating with HMG-CoA reductase inhibitors. (1994) (12)
- A proposed method for exploring anti-aggregatory effects of eicosapentaenoic acid in the rat. (1984) (12)
- Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression (2014) (12)
- Eicosapentaenoic acid abolishes the proatherogenic effects of cholesterol: effects on migration of bovine smooth muscle and endothelial cells in vitro. (1993) (12)
- Vascular endothelial growth factor promotes proliferation and function of hepatocyte-like cells in embryoid bodies formed from mouse embryonic stem cells. (2008) (12)
- Quantitative determination of 6-keto prostaglandin F1 alpha in biological fluids by capillary gas chromatography-chemical ionization mass spectrometry. (1980) (12)
- Age- and cell cycle-dependent changes in EPC-1/PEDF promoter activity in human diploid fibroblast-like (HDF) cells (2006) (12)
- Role of 12-lipoxygenase products of arachidonic acid on platelet aggregation. (1987) (11)
- Increased arachidonic acid incorporation into platelet phospholipids in Type 2 (non-insulin-dependent) diabetes (1984) (11)
- Inhibition of angiogenesis by erbstatin, an inhibitor of tyrosine kinase. (1993) (11)
- Amyloid &bgr; Enhances Migration of Endothelial Progenitor Cells by Upregulating CX3CR1 in Response to Fractalkine, Which May Be Associated With Development of Choroidal Neovascularization (2011) (11)
- Cerebellar nitric oxide synthase, cGMP and motor function in two lines of cerebellar mutant mice, Staggerer and Wriggle Mouse Sagami (1994) (10)
- Hydrogen peroxide induced apoptosis of endothelial cells concomitantly with cycloheximide. (2000) (10)
- NO is not involved in the simvastatin induced cell division and differentiation in PC12 cells (1998) (10)
- PREP1, MEIS1 homolog protein, regulates PF4 gene expression. (2003) (10)
- Development of a liquid culture system for megakaryocyte terminal differentiation: fibrinogen promotes megakaryocytopoiesis but not thrombopoiesis (2003) (10)
- Hyperoxia decreases cyclooxygenase activity in endothelial cells. (1993) (9)
- Dietary arachidonic acid supplementation increases thromboxane synthesizing activity in platelets from diabetics. (1983) (9)
- Prostaglandin E2 mediates parathyroid hormone induced osteoclast formation by cyclic AMP independent mechanism. (1997) (9)
- Effects of surface modification of materials on human neutrophil activation. (1995) (9)
- Characterization of thromboxane B2 and 6-ketoprostaglandin F alpha by combined gas chromatography and chemical-ionization mass spectrometry. (1978) (9)
- Endothelial cell migration and morphogenesis on silk fibroin scaffolds containing hydroxyapatite electret. (2012) (9)
- Spontaneous differentiation of periodontal ligament stem cells into myofibroblast during ex vivo expansion (2019) (9)
- The reduction in pigment epithelium-derived factor is a sign of malignancy in ovarian cancer expressing low-level of vascular endothelial growth factor (2009) (9)
- Eicosapentaenoic Acid Protects Endothelial Cell Function Injured by Hypoxia/Reoxygenation (2001) (8)
- Arachidonic acid pretreatment enhances smooth muscle cell migration via increased Ca2+ influx. (1998) (8)
- Cell transfer technology for tissue engineering (2017) (8)
- Effects of prostaglandin E2 on phenotype of osteoblasts-like cells. (1989) (8)
- [Regulation of cell growth by prostaglandins]. (1983) (8)
- Role of intercellular adhesion molecule‐2 in osteoclastogenesis (2012) (7)
- Involvement of cyclooxygenase-2 in bone loss induced by interleukin-1 beta. (1995) (7)
- Synthesis of prostaglandin F2α in rat liver (1977) (7)
- Effect of aging on the prostaglandin-synthesizing system in rat liver. (1980) (7)
- Prostaglandin E2 evokes intracellular calcium rise in mouse osteoblastic cell line, MC3T3E-1. (1990) (7)
- Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization (2017) (7)
- Importance of cyclooxygenase induction in the biosynthesis of prostacyclin. (1983) (6)
- Prostacyclin does not play any cytoprotective role in endothelial cell injury induced by 15-hydroperoxy-eicosatetraenoic acid, an arachidonate lipoxygenase product. (1990) (6)
- Angiogenic Effects of Secreted Factors from Periodontal Ligament Stem Cells (2021) (6)
- Induction of cyclooxygenase-1 in cultured synovial cells isolated from rheumatoid arthritis patients (2004) (6)
- Impaired polymorphonuclear leukocyte 15-lipoxygenase activity in juvenile and rapidly progressive periodontitis. (1988) (6)
- [Bone and Stem Cells. Mesenchymal stem cells and bone regeneration]. (2014) (6)
- Arachidonic acid metabolism by nuclei of a retinoic acid--or vitamin D3-differentiated human leukemia cell line HL-60. (1994) (6)
- The synergistic effect of elastase and hydrogen peroxide on vascular endothelial cell injury is due to the production of hydroxylradical in the endothelial cells. (1996) (6)
- A novel mode of stimulating platelet formation activity in megakaryocytes with peanut skin extract (2017) (5)
- Effects of Eicosapentaenoic acid on endothelial cell function (1999) (5)
- Cell adhesion molecules acting between C6 glioma and endothelial cells (2005) (5)
- Cytological Effects of Rubratoxin B: Morphological Change and Gap Junctional Intercellular Communication (1997) (5)
- Angiogenic factor of a rat mammary tumor cell line (RMT-1) (I). Secretion of two distinct angiogenic factors into serum-free conditioned medium by RMT-1 cells. (1991) (5)
- Optimized method for culturing outgrowth endothelial progenitor cells (2011) (5)
- Effect of dietary protein level on platelet aggregation in rat. (1985) (5)
- Kallikrein stimulates prostacyclin production in bovine vascular endothelial cells. (1984) (5)
- Pigpen, a nuclear coiled body component protein, is involved in angiogenesis (2010) (5)
- Priming effects of leukotriene B4 on endothelial cell injury induced by tpa-activated leukocytes (1992) (4)
- Age-related shift from the biosynthesis of prostacyclin to thromboxane A2 and change in cyclic AMP production in response to prostacyclin in human diploid fibroblasts. (1983) (4)
- A novel method for prostaglandin endoperoxide H synthase activity in individual intact cells. (1997) (4)
- Endothelial Cell Injury caused by 15-HPETE, a Lipoxygenase Product of Arachidonic acid (1990) (4)
- Involvement of eicosanoids in angiogenesis. (1991) (4)
- Tissue specific regulation of prostaglandin production: stimulation of 6-ketoprostaglandin F1alpha biosynthesis by rat kidney cytosol. (1979) (3)
- Trial of high myopia disease classification using MRI and prototyping of image analysis software (2012) (3)
- PP 2 B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun / Sp 1 interaction in A 431 cells (2009) (3)
- Induction of cyclooxygenase in osteoblasts and bone metabolism. (1991) (3)
- An in vitro Assay System for Measuring Both Vascular Permeability and Endothelial Cell Damage (1988) (3)
- A kallikrein induced new peptide stimulating prostacyclin production by vascular endothelial cells. (1989) (2)
- Comparison of arachidonic acid metabolism between myofibroblasts and fibroblasts isolated from rat palatal mucoperiosteum. (1988) (2)
- Phorbol ester enhances choline uptake in cultured porcine brain endothelial cells (1996) (2)
- Possible mechanisms of antithrombotic effect of eicosapentaenoic acid: species specificity. (1985) (2)
- Sera from patients with sepsis induce nitric oxide production in vascular smooth muscle cells. (2000) (2)
- Comparative study on the prostacyclin producing activities in bovine heart valves. (1981) (2)
- The Effect of High Glucose on Proliferation, Adhesion and Migration of Normal Human Corneal Epithelial Cells (2002) (2)
- Dipyridamole, an Anti-platelet Agent, Reduces the Vascular Endothelial Cell Injury Induced by Active Oxygen Species. (1995) (2)
- Simvastatin enhanced sodium nitroprusside-induced apoptosis of smooth muscle cells. An involvement of geranylgeraniol. (2000) (2)
- Prostaglandin and Arteriosclerosis: Effects of Eicosapentaenoic Acid (EPA) on Platelet Aggregation, Bleeding Time, Fatty Acid Composition of Plasma and Platelet in Man (1982) (2)
- Mechanism of Inhibitory Effect of Hypoxia/Reoxygenation on Gap Junctional Intercellular Communication of Vascular Endothelial Cells in Culture (2001) (1)
- Cytoprotective effect of protease inhibitors on vascular endothelial cell injury induced by PMA-stimuloted leukocytes. (1991) (1)
- [Regulation of angiogenesis-expression of VEGF receptors]. (1998) (1)
- Comparative Analysis of Retinal Fundus Images with the Distant Past Images Using a Vessel Extraction Technique (2016) (1)
- Immunohistochemical study of prostaglandin E in rat carrageenin granuloma. (1987) (1)
- Cytoprotective drugs for the endothelial and neuronal cell injury by lipid peroxides (1990) (1)
- TOXICOLOGY OF ENDOTHELIAL CELLS BY LIPID PEROXIDES AND ACTIVE OXYGENS-THE MECHANISM AND PREVENTION (1991) (1)
- CYTOPROTECTIVE EFFECTS OF GLUTATHIONE AND GLUTATHIONE PEROXIDASE ON ENDOTHELIAL CELL INJURY INDUCED BY LIPID PEROXIDATION (1991) (1)
- Existence of endogenous inhibitor(s) of prostaglandin endoperoxide H synthase activities in murine NIH3T3 fibroblasts. (1999) (1)
- [Arachidonate metabolites]. (2006) (1)
- [Endothelial cell function and angiogenesis]. (1996) (1)
- Mesenchymal stem cells ameliorate intra-amniotic inflammation-related neonatal complications in rats (2015) (1)
- Cathepsin L in Bone Marrow-Derived Endothelial Progenitor Cells is Required for Choroidal Neovascularization (2010) (1)
- [PPAR (peroxisome proliferator activated receptor), a factor that decides differentiation of adipocytes]. (1997) (1)
- Effect of acute nitrogen dioxide exposure on the prostacyclin synthesis in lung. (1981) (1)
- [Distribution of nitric oxide synthase activity in rat brain--analysis by high performance liquid chromatography]. (1993) (1)
- The mechanism of the stimulatory effect of kallikrein on prostacyclin production in vascular endothelial cells. (1989) (1)
- Kallikrein produces a new peptide that specifically stimulates prostacyclin formation in vascular endothelial cells by activating phospholipase A2. (1987) (1)
- 101. Prostaglandin I_2(Prostacycline) Synthesizing Activity of Human Ripening Uterin Cervix (1980) (0)
- Reduced Retinal and Choroidal Neovascularization in Cathepsin L Gene-Deficient Mice (2008) (0)
- A novel mode of stimulating platelet formation activity in megakaryocytes with peanut skin extract (2017) (0)
- Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis (2017) (0)
- Hypoxia antagonizes IL-1β-mediated transcriptional responses by the coordinated actions of HDAC, PHD and deacetylation of p65-subunit of NF-κB. (2016) (0)
- 81 Urinary 11-Dehydro TXB_2 during normal pregnancy. (1989) (0)
- Photoreceptor Protection by Iris Pigment Epithelial Transplantation Cultured on Amniotic Membrane (2006) (0)
- [Prostaglandins and related substances: metabolic pathways]. (1985) (0)
- Quantitative analysis of 6-keto-prostaglandin F1 alpha in biological fluids. (1985) (0)
- 1P324 Functional Membrane Protein Expression and Integration on Lipid Vesicles(Bioengineering, and new biophysical techniques and instrumentation,Oral Presentations) (2007) (0)
- 3.P.221 Involvement of Na+/H+ exchanger and intracellular pH in migration of bovine endothelial cells (1997) (0)
- Effect of hyaluronic acid on angiogenesis in rheumatoid arthritis (2000) (0)
- Subretinal Deposit Formation in Neprilysin Gene–disrupted Mice: An Important Role of Amyloid ß in the Pathogenesis of Age–related Macular Degeneration (2005) (0)
- Ebselen and sodium selenite, mimics of glutathione peroxidase, inhibit prostaglandin endoperoxide H synthase-2, but not prostaglandin endoperoxide H synthase-1 (1997) (0)
- Erratum to “A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol”: [Biochim. Biophys. Acta 1327 (1997) 222–230]1PII of the original article: S0005-2736(97)00061-8.1 (1998) (0)
- Change of arachidonic acid metabolism in inflamed rat dental pulp. (1987) (0)
- Introduction to the special issue "The interaction among bone immunology and vascular biology" (2011) (0)
- Effects of eicosapentaenoic acid (EPA) on platelet aggregation, blood coagulation, blood lipid and fatty acid composition of plasma and platelet in man (1983) (0)
- Is Apoptosis Involved in Glutamate Neurotoxicity (1997) (0)
- UTILITY OF URINARY 11-DEHYDRO-TXB_2 AS A INDEX OF PLATELET ACTIVATION IN VIVO IN PATIENTS WITH VALVULAR HEART DISEASE : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society (1989) (0)
- P088 The involvement of IL-6 receptor and GP130 in osteoclast differentiation and function in postmenopause (1996) (0)
- Neuroprotective effects of human umbilical cord-derived mesenchymal stem cells on periventricular leukomalacia-like brain injury in neonatal rats (2017) (0)
- Time-dependent Increase of Platelet-activating Factor Acetylhydrolase in the Culture Medium of Mouse Calvaria. (1992) (0)
- Pharmacological analysis on the rise of the nuclear calcium by glutamate and its role in neuronal cell death (2000) (0)
- IN VITRO MODEL FOR REMODELING OF THE SPIRAL ARTERY BY TROPHOBLASTIC CELLS (2012) (0)
- 46. PGI_2 Synthesizing Activity in Smooth Muscle Cell Derived from Rabbit Rippening Cervix (1986) (0)
- Inhibition of Cathepsin L Causes a Reduced Neovascularization in the Retina and Choroid (2007) (0)
- The correlation between sirt1 and Muller cells in the development of CNV (2016) (0)
- Amlodipine modulates monocyte adhesion to vascular endothelium under physiological flow condition via inhibition of RhoA GTPase. (2002) (0)
- 3.P.248 Pretreatment with simvastatin caused synergestic effect on sodium nitroprusside-induced apoptosis of smooth muscle cells (1997) (0)
- Synthesis of prostaglandin F2alpha in rat liver. (1977) (0)
- N-3 Polyunsaturated Fatty Acids and Bone Metabolism (2000) (0)
- Vascular Endothelial Growth Factor Up-Regulates Pigment Epithelium-Derived Factor Expression via VEGFR-1 in Human Retinal Pigment Epithelial Cells (2003) (0)
- P-31 Acidosis promotes preosteoclast differentiation : A research to elucidate the major action point and putative target molecules (2011) (0)
- Expression of Interactive Laser Cytometer : Neutrophil Adhesion Molecules in preeclampsi (1995) (0)
- Amyloid β enhances expression and activity of HTRA1 in retinal pigment epithelial cells, a mechanism of wet age-related macular degeneration development from drusen (2013) (0)
- The Mechanism of Vascular Endothelial Cell Injury Caused by Activated Leukocytes and Platelets (1990) (0)
- 3.P.222 Suppression of gap junctional intercellular communication in HUVEC by neutrophil adhesion (1997) (0)
- The Quantification and the Control of Vascular Endothelial Cell Injury (1988) (0)
- Inhibitory Effects of Antioxidants on NF-KappaB Activation in Bovine Carotid Artery Endothelial Cells. (2000) (0)
- S5-2 ROLE OF NEURONAL GLUTAMATE TRANSPORTER IN THE CYSTEINE UPTAKE AND INTRACELLULAR GLUTATHIONE LEVELS IN CULTURED CORTICAL NEURONS(SYMPOSIUM 5: PHYSIOLOGY AND DISEASE OF GLUTAMATE IN NEURONAL AND GLIAL CELLS)(Proceedings of the 31st Annual Meeting) (2004) (0)
- TGF-β switches isoform of FGF receptors and epithelial-mesenchymal transition (2010) (0)
- 446 Luminol-dependent chemiluminescence (CL) of peripheral neutrophils in preterm labor. (1991) (0)
- [Preventive effects of supplemental n-3 polyunsaturated fatty acids on metabolic syndromes]. (2006) (0)
- Effects of Cadmium on Bone Metabolism (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology) (1989) (0)
- COMPUTER-AIDED 2 DIMENSIONAL CAPILLARY VASCULATURE DESIGNING AND ENGINEERING (2004) (0)
- Effects of eicosapentaenoic acid (EPA) and dochosahexaenoic acid (DHA) on hemostasis, blood lipids and fatty acid composition of plasma and platelet in man (1984) (0)
- Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin A4 contents in colon, but does not affect severity or prostaglandin E2 content in murine colitis model (2014) (0)
- Cytoprotective effects of glutathione and glutathione peroxidase on endothelial cell injury by lipid peroxide (1990) (0)
- 120. Prostaglandin I_2(prostacyclin) Synthesizing Activity of Rabbit Uterine Cervix during Gestation (1981) (0)
- Significance of up and down regulation of vascular endothelial growth factor receptor in angiogenesis (2000) (0)
- Molecular Mechanism of the Enhanced Migration of Endothelial Progenitor Cells Induced by Amyloid β (2010) (0)
- Cell transfer technology for tissue engineering (2017) (0)
- Mechanism of Endothelial Cell Injury Induced by Activated Leukocytes (1993) (0)
- Visual arrestin modulates gene expression in the retinal pigment epithelium: Implications for homeostasis in the retina (2019) (0)
- 3.P.230 Effect of estrogen on synthesis of prostacyclin in cultured bovine endothelial cells (1997) (0)
- Endometrium and angiogenesis : Isolation of human endometrial epithelial cells and production of angiogenic factors (2000) (0)
- 2P342 Chaperone-like function of liposomes for cell-free synthesized membrane protein(The 48th Annual Meeting of the Biophysical Society of Japan) (2010) (0)
- [Intracellular communication through connexin]. (2003) (0)
- In vitro capillary engineering and angioplasty (2006) (0)
- Amyloid–beta regulates gene expression of angiogenesis–related factors in human retinal pigment epithelial cells. (2004) (0)
- Polyunsaturated Fatty Acids Regulate the Expression of VEGF and MCP-1 in Human Retinal Pigment Epithelial Cells (2003) (0)
- 3P318 Artificial cells equipped with cellular connection mechanism (2005) (0)
- Amyloid-β Regulates the Gene Expression Profile of Matrix Metalloproteinases in Human Retinal Pigment Epithelial Cells (2008) (0)
- P1-59 Metabolic acidosis is a contributor to bone absorption with multiple action points (2007) (0)
- Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model (2015) (0)
- Effects of n-3 polyunsaturated fatty acids on the susceptibility to VEGF through down-regulation of VEGFR-2 expression (2006) (0)
- 3.P.224 Different regulation of prostaglandin endoperoxide H synthase-1 and -2 activities by nitric oxide in vascular endothelial cells (1997) (0)
- 22. Effect of DHA-S on PGI_2 Synthesizing Activity of Rabbit Uterine Cervix (1982) (0)
- PI-25 Metabolic acidosis is a contributor to bone resorption with various action points : (2008) (0)
- REGULATION OF PIGMENT EPITHELIUM-DERIVED FACTOR (PEDF) PRODUCTION—ROLE IN THE DEVELOPMENT OF CHOROIDAL NEOVASCULARIZATION OF AGE-RELATED MACULAR DEGENERATION (2004) (0)
- Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels. (1994) (0)
- Collagen synthesizing activity in myofibroblasts isolated from scar tissue in rat oral mucoperiosteum. (1988) (0)
- Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells (2001) (0)
- Synergistic effect of elastase and hydrogen peroxide on vascular enfdothelial cell injury. (1992) (0)
- Role of SERCA 2 b in mobilization of nuclear Ca 2 + in HeLa cells (2002) (0)
- EPA pretreatment inhibited the tube formation of endothelial cells induced by LTC4. (1992) (0)
- Qualitative And Quantitative Analyses Of The Eye Shape Of Pathologic Myopia Obtained By High-resolution 3D MRI (2012) (0)
- Endothelial cells pretreated with high glucose enhanced the expression of FLK-I/KDR and angiogenesis induced by VEGF (1999) (0)
- [Gap junctional intercellar communication through connexins]. (2003) (0)
- 133 Urinary 11-dehydro TXB2 during toxemic pregnancies. (1990) (0)
- Cytoprotective effect of protease inhibitors of endothelial cell injury induced by activated leukocytes (1990) (0)
- Amyloid Beta Enhances Migration Of Endothelial Progenitor Cells Via Upregulation Of CX3CR1 (2011) (0)
- PI-16 Metabolic acidosis acts on the last phase of osteoclast differentiation to promote cell fusion (2009) (0)
- Variation of increases in free cytosolic calcium ion induced by prostaglandin E2 in mouse osteoblast clone, MC3T3-E1—Single cell assay using microspectro-fluorometry (1991) (0)
- A novel rat model of intra-uterine infection using lipopolysaccharide: evaluation of placental and neonatal complications (2014) (0)
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