Inderjit Singh
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Inderjit Singh's Degrees
- PhD Computer Science Stanford University
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(Suggest an Edit or Addition)Inderjit Singh's Published Works
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Published Works
- Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. (1997) (597)
- 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase* (2005) (337)
- 5-Aminoimidazole-4-Carboxamide-1-β-4-Ribofuranoside Inhibits Proinflammatory Response in Glial Cells: A Possible Role of AMP-Activated Protein Kinase (2004) (274)
- Hepatocellular and Hepatic Peroxisomal Alterations in Mice with a Disrupted Peroxisomal Fatty Acyl-coenzyme A Oxidase Gene* (1996) (243)
- Adrenoleukodystrophy: Survey of 303 cases: Biochemistry, diagnosis, and therapy (1984) (241)
- Administration of N‐acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke (2004) (227)
- Adrenoleukodystrophy: Impaired Oxidation of Very Long Chain Fatty Acids in White Blood Cells, Cultured Skin Fibroblasts, and Amniocytes (1984) (214)
- Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis1 (2009) (211)
- Cytokine-mediated Induction of Ceramide Production Is Redox-sensitive (1998) (208)
- Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. (1988) (202)
- Long-Chain Acyl Coenzyme A Dehydrogenase Deficiency: An Inherited Cause of Nonketotic Hypoglycemia (1985) (187)
- Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms (2006) (183)
- Kidney ischemia-reperfusion: Modulation of antioxidant defenses (2000) (183)
- Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin (1999) (175)
- AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model (2006) (173)
- Sphingomyelinase and Ceramide Stimulate the Expression of Inducible Nitric-oxide Synthase in Rat Primary Astrocytes* (1998) (169)
- Potential Targets of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor for Multiple Sclerosis Therapy (2004) (168)
- N‐acetylcysteine prevents endotoxin‐induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain (2004) (168)
- N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes. (1998) (163)
- N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia (2003) (159)
- Lignoceroyl‐CoASH ligase: enzyme defect in fatty acid β‐oxidation system in X‐linked childhood adrenoleukodystrophy (1986) (158)
- S-Nitrosoglutathione Reduces Inflammation and Protects Brain against Focal Cerebral Ischemia in a Rat Model of Experimental Stroke (2005) (153)
- 5-Aminoimidazole-4-Carboxamide Ribonucleoside: A Novel Immunomodulator with Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis1 (2005) (147)
- Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis (2001) (145)
- Increasing cAMP Attenuates Induction of Inducible Nitric-oxide Synthase in Rat Primary Astrocytes* (1997) (143)
- The 15-Deoxy-δ12,14-Prostaglandin J2 Inhibits the Inflammatory Response in Primary Rat Astrocytes via Down-Regulating Multiple Steps in Phosphatidylinositol 3-Kinase-Akt-NF-κB-p300 Pathway Independent of Peroxisome Proliferator-Activated Receptor γ1 (2004) (134)
- Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats (2005) (133)
- Sphingolipid signaling and redox regulation. (2006) (131)
- Inhibition of Phosphatidylinositol 3-Kinase Induces Nitric-oxide Synthase in Lipopolysaccharide- or Cytokine-stimulated C6 Glial Cells* (1999) (130)
- Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact (2009) (129)
- Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. (2004) (124)
- Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis (2009) (119)
- Biochemistry of peroxisomes in health and disease (1997) (119)
- Pathomechanisms Underlying X‐Adrenoleukodystrophy: A Three‐Hit Hypothesis (2009) (119)
- Combination of Systemic Hypothermia and N-acetylcysteine Attenuates Hypoxic-Ischemic Brain Injury in Neonatal Rats (2006) (117)
- Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy (2007) (113)
- Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death (2008) (112)
- Lovastatin for X-linked adrenoleukodystrophy. (1998) (110)
- Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia (2007) (107)
- Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death Published, JLR Papers in Press, April 27, 2006. (2006) (106)
- Molecular mechanism of psychosine‐induced cell death in human oligodendrocyte cell line (2003) (105)
- Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies (2003) (105)
- Demonstration of Cu-Zn superoxide dismutase in rat liver peroxisomes. Biochemical and immunochemical evidence. (1992) (105)
- Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke. (2006) (100)
- The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells. (1999) (99)
- Galactosylsphingosine (psychosine) ‐induced expression of cytokine‐mediated inducible nitric oxide synthases via AP‐1 and C/EBP: implications for Krabbe disease (2002) (98)
- Post‐trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury (2006) (98)
- Bone marrow transplant in adrenoleukodystrophy (1984) (95)
- S-Nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats (2011) (95)
- Modulation of Endogenous Antioxidant Enzymes by Nitric Oxide in Rat C6 Glial Cells (1997) (93)
- Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X‐ adrenoleukodystrophy (1998) (92)
- Inhibitors of Protein Phosphatase 1 and 2A Differentially Regulate the Expression of Inducible Nitric-oxide Synthase in Rat Astrocytes and Macrophages* (1998) (92)
- Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia (2006) (91)
- Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury (1993) (91)
- Synergistic activity of interleukin‐17 and tumor necrosis factor‐α enhances oxidative stress‐mediated oligodendrocyte apoptosis (2011) (89)
- Rhinovirus-Induced Oxidative Stress and Interleukin-8 Elaboration Involves p47-phox but Is Independent of Attachment to Intercellular Adhesion Molecule-1 and Viral Replication (2000) (88)
- Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. (2006) (88)
- T‐bet is essential for the progression of experimental autoimmune encephalomyelitis (2006) (87)
- Mammalian Peroxisomes: Metabolism of Oxygen and Reactive Oxygen Species (1996) (86)
- Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: Attenuation by N-acetyl cysteine (2008) (86)
- HMG‐CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis (2005) (83)
- GSNO attenuates EAE disease by S‐nitrosylation‐mediated modulation of endothelial‐monocyte interactions (2007) (81)
- Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin (2002) (78)
- Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin (2004) (76)
- Abnormality in catalase import into peroxisomes leads to severe neurological disorder. (1998) (76)
- Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin (2008) (75)
- IL-4-Induced Peroxisome Proliferator-Activated Receptor γ Activation Inhibits NF-κB Trans Activation in Central Nervous System (CNS) Glial Cells and Protects Oligodendrocyte Progenitors under Neuroinflammatory Disease Conditions: Implication for CNS-Demyelinating Diseases1 (2006) (75)
- STAT3 regulation by S‐nitrosylation: implication for inflammatory disease (555.8) (2014) (73)
- Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity. (2009) (73)
- The protein coded by the X‐adrenoleukodystrophy gene is a peroxisomal integral membrane protein (1994) (72)
- Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis. (2010) (72)
- Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. (1989) (72)
- Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis (2008) (71)
- The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe Disease (2008) (71)
- Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients. (2000) (69)
- Interleukin‐10 and Interleukin‐13 Inhibit Proinflammatory Cytokine‐Induced Ceramide Production Through the Activation of Phosphatidylinositol 3‐Kinase (2000) (68)
- 5‐aminoimidazole‐4‐carboxamide‐1‐beta‐4‐ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial–monocyte interaction (2006) (67)
- Topographical localization of peroxisomal acyl-CoA ligases: differential localization of palmitoyl-CoA and lignoceroyl-CoA ligases. (1990) (65)
- Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment (2004) (63)
- Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney. (1992) (63)
- A Novel Role of Lactosylceramide in the Regulation of Lipopolysaccharide/Interferon-γ-Mediated Inducible Nitric Oxide Synthase Gene Expression: Implications for Neuroinflammatory Diseases (2004) (63)
- The inhibitory effect of S‐nitrosoglutathione on blood–brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke (2012) (62)
- Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice. (2011) (62)
- Inducible Nitric Oxide Synthase in the Central Nervous System of Patients with X‐Adrenoleukodystrophy (2000) (62)
- Rho/ROCK pathway as a target of tumor therapy (2006) (60)
- Postnatal Development and Isolation of Peroxisomes from Brain (1991) (59)
- Peroxisomal participation in psychosine‐mediated toxicity: Implications for Krabbe's disease (2005) (59)
- Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis (2009) (58)
- Demonstration of glutathione peroxidase in rat liver peroxisomes and its intraorganellar distribution. (1994) (57)
- Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. (1993) (57)
- The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide‐mediated expression of inducible nitric oxide synthase (2003) (55)
- Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy. (1992) (55)
- The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma. (2004) (54)
- Peroxisomal disorders. Neurodevelopmental and biochemical aspects. (1993) (52)
- Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. (1993) (51)
- Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. (2003) (51)
- Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy. (2003) (50)
- Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion. (2012) (50)
- N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats (2005) (50)
- Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes. (1996) (49)
- Increased Plp1 gene expression leads to massive microglial cell activation and inflammation throughout the brain (2010) (49)
- Inhibition of phosphoinositide 3 kinase‐Akt (protein kinase B)–nuclear factor‐κB pathway by lovastatin limits endothelial–monocyte cell interaction (2005) (49)
- Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. (1990) (47)
- S-nitrosoglutathione a Physiologic Nitric Oxide Carrier Attenuates Experimental Autoimmune Encephalomyelitis (2010) (47)
- Lactosylceramide: a lipid second messenger in neuroinflammatory disease (2007) (46)
- Cytokine‐Induced Accumulation of Very Long‐Chain Fatty Acids in Rat C6 Glial Cells: Implication for X‐Adrenoleukodystrophy (1998) (46)
- 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia (2005) (46)
- Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (46)
- The Involvement of Glucose Metabolism in the Regulation of Inducible Nitric Oxide Synthase Gene Expression in Glial Cells: Possible Role of Glucose-6-Phosphate Dehydrogenase and CCAAT/Enhancing Binding Protein (2003) (45)
- Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion. (2013) (44)
- Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability. (2004) (44)
- Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress. (1997) (43)
- Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney (2002) (43)
- Lignoceroyl-CoA ligase activity in rat brain microsomal fraction: topographical localization and effect of detergents and alpha-cyclodextrin. (1985) (43)
- Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. (1998) (43)
- A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. (2005) (43)
- Oxidative Imbalance in Nonstimulated X-Adrenoleukodystrophy-Derived Lymphoblasts (2009) (42)
- Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats (2015) (42)
- Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. (2010) (42)
- Endotoxin-induced alterations of lipid and fatty acid compositions in rat liver peroxisomes (2000) (42)
- Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion (1997) (41)
- Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease. (2006) (41)
- Antioxidant enzymes in ciprofibrate-induced oxidative stress. (1994) (40)
- Activation of PPAR‐γ and PTEN cascade participates in lovastatin‐mediated accelerated differentiation of oligodendrocyte progenitor cells (2010) (40)
- AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model. (2013) (39)
- Attenuation of Lipopolysaccharide-Induced Inflammatory Response and Phospholipids Metabolism at the Feto-Maternal Interface by N-Acetyl Cysteine (2008) (39)
- Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat (2009) (39)
- Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis (2008) (39)
- Modulation of peroxisome proliferator‐activated receptor‐α activity by N‐acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures (2008) (39)
- Lovastatin inhibits amyloid precursor protein (APP) β‐cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts (2008) (39)
- Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. (2006) (38)
- Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy (2010) (36)
- Acyl-CoA ligases from rat brain microsomes: an immunochemical study. (1988) (36)
- Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI (2016) (34)
- Modulation of Rho‐Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR‐α‐dependent mechanism (2013) (34)
- Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy. (2000) (34)
- HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes (2011) (34)
- ABCD1 deletion‐induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy (2015) (34)
- Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy (2015) (33)
- Characterization of rat brain microsomal acyl-coenzyme A ligases: different enzymes for the synthesis of palmitoyl-coenzyme A and lignoceroyl-coenzyme A. (1986) (33)
- Peroxisomal disorders. Biochemical and clinical diagnostic considerations. (1988) (33)
- N-acetylcysteine attenuates the maternal and fetal proinflammatory response to intrauterine LPS injection in an animal model for preterm birth and brain injury (2011) (33)
- Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease (2016) (32)
- S-Nitrosoglutathione Induces Ciliary Neurotrophic Factor Expression in Astrocytes, Which Has Implications to Protect the Central Nervous System under Pathological Conditions* (2012) (32)
- Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: Implication for Krabbe disease (2013) (32)
- Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia (2016) (32)
- Mitochondrial abnormalities in CLN2 and CLN3 forms of Batten disease. (1996) (31)
- S‐nitrosoglutathione prevents blood–brain barrier disruption associated with increased matrix metalloproteinase‐9 activity in experimental diabetes (2015) (31)
- Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes. (1995) (30)
- Increased peroxisomal fatty acid β-oxidation and enhanced expression of peroxisome proliferator-activated receptor-α in diabetic rat liver (1999) (30)
- Nitric Oxide Regulates Peroxisomal Enzyme Activities (1995) (30)
- The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats. (2005) (29)
- Hypoxia inducible factor-1 alpha stabilization for regenerative therapy in traumatic brain injury (2017) (29)
- Therapeutic potential of statins in multiple sclerosis: immune modulation, neuroprotection and neurorepair. (2008) (28)
- Increased peroxisomal fatty acid beta-oxidation and enhanced expression of peroxisome proliferator-activated receptor-alpha in diabetic rat liver. (1999) (28)
- Endotoxin induces structure‐function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators (2000) (26)
- Induction of the Manganese Superoxide Dismutase Gene by Sphingomyelinase and Ceramide (1999) (26)
- Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP. (1998) (26)
- Simvastatin protects bladder and renal functions following spinal cord injury in rats (2010) (26)
- Peroxisomal Dysfunction in Inflammatory Childhood White Matter Disorders: An Unexpected Contributor to Neuropathology (2009) (26)
- Preclinical use of longitudinal MRI for screening the efficacy of s‐nitrosoglutathione in treating spinal cord injury (2011) (26)
- Cardiovascular Disease, Statins, and HIV. (2016) (25)
- Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide‐induced inducible nitric oxide synthase expression in glial cells (2005) (25)
- Phytanic acid α-oxidation in human cultured skin fibroblasts (1992) (24)
- Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. (1993) (24)
- Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts. (1991) (24)
- Effect of nitric oxide on rhinovirus replication and virus-induced interleukin-8 elaboration. (1999) (24)
- Effect of Salicylic Acid on Mitochondrial-Peroxisomal Fatty Acid Catabolism (1988) (23)
- Tissue differences in antioxidant enzyme gene expression in response to endotoxin (1996) (23)
- S-nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma☆ (2015) (23)
- GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1α (2018) (22)
- Targeted Disruption of the Peroxisomal Fatty Acyl‐CoA Oxidase Gene: Generation of a Mouse Model of Pseudoneonatal Adrenoleukodystrophy a (1996) (22)
- Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix. (2006) (22)
- Degradation of myelin proteins by brain endogenous neutral protease (1983) (22)
- Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy (2015) (21)
- Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes. (1993) (21)
- Presence of heterogeneous peroxisomal populations in the rat nervous tissue. (1998) (21)
- Manganese superoxide dismutase in rat liver peroxisomes: Biochemical and immunochemical evidence (1999) (20)
- Combinatorial Effect of Metformin and Lovastatin Impedes T-cell Autoimmunity and Neurodegeneration in Experimental Autoimmune Encephalomyelitis. (2013) (20)
- Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis (2013) (19)
- Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes. (2013) (19)
- N-acetylcysteine prevents preterm birth by attenuating the LPS-induced expression of contractile associated proteins in an animal model (2012) (19)
- Histone Deacetylase Inhibitor Upregulates Peroxisomal Fatty Acid Oxidation and Inhibits Apoptotic Cell Death in Abcd1-Deficient Glial Cells (2013) (19)
- Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. (2012) (19)
- Psychosine-induced alterations in peroxisomes of twitcher mouse liver. (2008) (18)
- Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer’s Disease (2018) (18)
- 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases (2008) (18)
- Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats (2015) (17)
- Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata. (1996) (17)
- S‐Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide‐induced sepsis (2016) (17)
- Combination therapy of lovastatin and AMP‐activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model (2018) (16)
- Neuroprotective Interventions: Is It Too Late? (2009) (16)
- Peroxisomal participation in the cellular response to the oxidative stress of endotoxin (1993) (16)
- S-nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161-180))-induced experimental autoimmune uveitis. (2007) (16)
- Regulation of STAT3 and NF‐&kgr;B activations by S‐nitrosylation in multiple myeloma (2017) (16)
- Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis. (1996) (15)
- Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice (2013) (15)
- Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells (2005) (15)
- Spinal cord injury induced arrest in estrous cycle of rats is ameliorated by S-nitrosoglutathione: novel therapeutic agent to treat amenorrhea. (2012) (15)
- Vitamin D improves functional outcomes in neonatal hypoxic ischemic male rats treated with N-acetylcysteine and hypothermia (2017) (15)
- S‐Nitrosoglutathione protects the spinal bladder: Novel therapeutic approach to post‐spinal cord injury bladder remodeling (2015) (15)
- Effect of hypoxia-reoxygenation on peroxisomal functions in cultured human skin fibroblasts from control and Zellweger syndrome patients. (1995) (15)
- Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation. (2015) (15)
- Fatty acid α-hydroxylation and its relation to myelination (1979) (14)
- Pseudo Infantile Refsum's Disease: Catalase-Deficient Peroxisomal Particles with Partial Deficiency of Plasmalogen Synthesis and Oxidation of Fatty Acids (1993) (14)
- Factors that affect postnatal bone growth retardation in the twitcher murine model of Krabbe disease. (2010) (14)
- S‐nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis (2018) (14)
- Inhibition of peroxisomal functions due to oxidative imbalance induced by mistargeting of catalase to cytoplasm is restored by vitamin E treatment in skin fibroblasts from Zellweger syndrome-like patients. (2004) (14)
- Effect of fatty acids and their derivatives on mitochondrial structures. (1989) (13)
- Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries. (2019) (13)
- Hypoxia‐inducible factor‐1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases (2021) (13)
- Kinetic characteristics of rat liver peroxisomal nafenopin-CoA ligase. (1995) (13)
- Effect of salicylic acid and calcium on mitochondrial functions (1992) (13)
- Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease (2015) (13)
- Identification of the pathway of α-oxidation of cerebronic acid in peroxisomes (2000) (12)
- Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (2010) (12)
- Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid α‐oxidation (1995) (12)
- S-Nitrosoglutathione administration ameliorates cauda equina compression injury in rats. (2012) (12)
- Effect of Rhinovirus Challenge on Antioxidant Enzymes in Respiratory Epithelial Cells (2002) (12)
- MicroRNA Profiling Identifies miR-196a as Differentially Expressed in Childhood Adrenoleukodystrophy and Adult Adrenomyeloneuropathy (2017) (11)
- Protective effect of S-nitrosoglutathione administration against hyperglycemia induced disruption of blood brain barrier is mediated by modulation of tight junction proteins and cell adhesion molecules (2018) (11)
- Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione. (2018) (11)
- Isolation and Biochemical Characterization of Peroxisomes from Cultured Rat Glial Cells (2000) (11)
- Restoration of phytanic acid oxidation in Refsum disease fibroblasts from patients with mutations in the phytanoyl‐CoA hydroxylase gene (1998) (11)
- STAT3 Regulation By S-Nitrosylation: Implication In Cancer. (2015) (10)
- [31] Peroxisomal fatty acid oxidation and cellular redox (2002) (10)
- Thioridazine induces lipid peroxidation in myelin of rat brain (1993) (10)
- S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke. (2019) (10)
- S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion (2015) (10)
- Abnormality in Translational Regulation of Catalase Expression in Disorders of Peroxisomal Biogenesis (1996) (9)
- Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI (2018) (9)
- An NO/GSNO-based Neuroregeneration Strategy for Stroke Therapy (2015) (8)
- Late-onset generalized disorder of peroxisomes (1996) (8)
- Peroxisomal enzyme activities in brain and liver of pups of lactating mothers treated with ciprofibrate (1992) (8)
- A Novel Role of Lactosylceramide in the Regulation of Tumor Necrosis Factor α-mediated Proliferation of Rat Primary Astrocytes (2005) (7)
- S-Nitrosylation in Regulation of Inflammation and Cell Damage. (2018) (7)
- AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis (2015) (7)
- Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis. (2019) (7)
- Effect of clofibrate on peroxisomal lignoceroyl-CoA ligase activity. (1990) (7)
- Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathology (2020) (6)
- Impairment of peroxisomal β-oxidation system by endotoxin treatment (1994) (6)
- Regulation of B cell functions by S-nitrosoglutathione in the EAE model (2021) (6)
- Peroxisomal fatty acid oxidation and cellular redox. (2002) (6)
- Effect of ciprofibrate on the activation and oxidation of very long chain fatty acids (1991) (6)
- Implication for CNS-Demyelinating Diseases Neuroinflammatory Disease Conditions: Protects Oligodendrocyte Progenitors under Nervous System (CNS) Glial Cells and Activation in Central Trans B k Inhibits NF-Activation g Proliferator-Activated Receptor IL-4-Induced Peroxisome (2006) (6)
- Autoimmune Encephalomyelitis with Therapeutic Efficacy in Experimental Ribonucleoside: A Novel Immunomodulator 5-Aminoimidazole-4-Carboxamide (2005) (6)
- Biochemical Features of a Patient with Zellweger-like Syndrome with Normal PTS-1 and PTS-2 Peroxisomal Protein Import Systems: A New Peroxisomal Disease (1997) (6)
- Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes. (2000) (5)
- Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity (2018) (5)
- CuZn Superoxide Dismutase: Intraorganellar Distribution in Peroxisomes a (1994) (5)
- Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms (2021) (5)
- Phytanic acid alpha-oxidation in rat liver mitochondria. (1994) (5)
- Downregulation of Cellular Energy Sensor during Disease condition results in Alteration of Lipid Homeostasis in Immune Cells (2008) (5)
- Impairment of peroxisomal beta-oxidation system by endotoxin treatment. (1994) (5)
- NAC and Vitamin D Restore CNS Glutathione in Endotoxin-Sensitized Neonatal Hypoxic-Ischemic Rats (2021) (5)
- Detoxification of Reactive Aldehydes by Alda-1 Treatment Ameliorates Experimental Autoimmune Encephalomyelitis in Mice (2021) (4)
- Investigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research (2020) (4)
- 72 Topographical localization of Peroxisomal Acyl-CoA Ligases: Differential localization of Palmitoyl-CoA and Lignoceroyl-CoA Ligases (1990) (4)
- Modulation of Endogenous Antioxidant Enzymes by Nitric Oxide in Rat C6 Glial Cells † 1722 (1997) (4)
- Effect of proteolipid protein on central nervous system myelin membrane fluidity (1985) (4)
- Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke (2020) (4)
- Fatty Acid Metabolism in Cultured Skin Fibroblasts from Patients with Peroxisomal Disorders: Lignoceroyl-CoA Ligase Deficiency in Childhood Adrenoleukodystrophy (1987) (4)
- Association of Alterations of Cellular Redox Pathways with Rhinovirus(RV)-Induced Interleukin-8 (IL-8) Elaboration in Respiratory Epithelial Cells† 722 (1997) (3)
- GSNOR and ALDH2 alleviate traumatic spinal cord injury (2021) (3)
- In situ genetic complementation analysis of cells with generalized peroxisomal dysfunction. (1989) (3)
- Peroxisomal activation, transport and oxidation of fatty acids: implications to peroxisomal disorders. (1992) (3)
- Peroxisomal oxidation of lignoceric acid in rat brain (1986) (3)
- CuZn superoxide dismutase: intraorganellar distribution in peroxisomes. (1994) (3)
- Adrenoleukodystrophy: Molecular, Metabolic, Pathologic, and Therapeutic Aspects (2009) (2)
- Erratum: Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα (Laboratory Investigation (2010) 90 (696-708) DOI: 10.1038/labinvest.2010.46) (2010) (2)
- Therapeutic exploitation of the S-nitrosoglutathione/S-nitrosylation mechanism for the treatment of contusion spinal cord injury (2019) (2)
- Purification and characterization of palmitoyl-CoA ligase from rat brain microsomes. (1987) (2)
- Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes. (1992) (2)
- Inhibition of the AMPK/nNOS pathway for neuroprotection in stroke (2016) (2)
- N‐acetyl cysteine protects against injury in animal model of transient focal cerebral ischemia (2008) (2)
- Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis (2021) (2)
- Ischemia-reperfusion alterations in the structure-function of peroxisomes (1993) (2)
- Anti-diabetic drug, metformin protects oligodendrocytes under CNS pathological conditions: implication for multiple sclerosis (P5205) (2013) (2)
- Levels and syntheses of cerebrosides and sulfatides in subcellular fractions of jimpy mutants (1981) (1)
- Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats. (1990) (1)
- Correction of mitochondrial and peroxisomal defects by lovastatin and AICAR in EAE. (2017) (1)
- Preclinical screening of a potential drug treatment for spinal cord injury using magnetic resonance imaging (2008) (1)
- PPARα Activation Induces Nε-Lys-Acetylation of Rat Liver Peroxisomal Multifunctional Enzyme Type 1 (2014) (1)
- Reye syndrome: rate of oxidation of fatty acids in leukocytes and serum levels of lipid peroxides. (1989) (1)
- Rhinovirus (RV)-Induced Interleukin-8 (IL-8) Production in Respiratory Epithelial Cells is Mediated by H2O2 and is Inhibited by N-Acetyl Cysteine (NAC) † 690 (1997) (1)
- Antioxidant enzymes system in peroxisomes (1993) (1)
- 73 Rhizomelic Chondrodysplasia Punctata: Metabolic Studies in Isolated Peroxisomes (1990) (1)
- Phytanic acid alpha-oxidation in human cultured skin fibroblasts. (1992) (1)
- Sphingolipids in rat model of transient focal cerebral ischemia: implication for stroke injury (2008) (1)
- Effect of ciprofibrate on peroxisomal antioxidant-enzyme system in rat liver (1993) (1)
- Inhibition of peroxisomal functions and production of excessive oxidative stress by psychosine in rat C6 glial cells (2008) (1)
- Novel mechanism in autoimmune regulation by S-nitrosoglutathione (2016) (0)
- Peroxisomal Proliferation Prevents Loss of Oligodendrocyte Progenitors and Hypomyelination in Periventricular Leukomalacia‐like Brain (2007) (0)
- S-Nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions. (2013) (0)
- 110: N-acetylcysteine prevents preterm birth in an intrauterine inflammatory model of preterm labor (2008) (0)
- Researchprotects bladder and renal functions following spinal cord injury in rats (2010) (0)
- IN PRESS OF Serial Review : Redox-Regulated Phospholipase Signal Transduction Serial Review (2006) (0)
- Oral Presentation OR1: Myelin, Oligodendrocyte, and Schwann Cell Biology (2004) (0)
- Hepatic toxicity in twitcher mice: effect on peroxisomes (2007) (0)
- Poster Sessions CP1: Astrocytes and C6 Cells (2004) (0)
- B cell-mediated immunomodulation by S-nitrosoglutathione (GSNO) in experimental autoimmune encephalomyelitis (2020) (0)
- Impaired oxidation of Nervonic acid in fibroblasts of patients with Zellweger Syndrome and X-linked Adrenoleukodystrophy. † 622 (1997) (0)
- Hepatic toxicity in twitcher mice: effect on peroxisomes: 558.10 (2007) (0)
- Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis (2012) (0)
- Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity (2018) (0)
- Animal Models of Multiple Sclerosis Disease of the Central Nervous System in Metformin Attenuated the Autoimmune (2009) (0)
- Metformin, a diabetic drug attenuated autoimmune inflammatory disease of CNS in animal models of multiple sclerosis (2008) (0)
- S-Nitrosoglutathione Protects Against Secondary Inflammatory Effects of Acute Spinal Cord Injury in Rats (2012) (0)
- KUPFFER CELLS MODULATE THE LIPOPOLYSACCHARIDE-INDUCED LIPID ALTERATIONS IN RAT LIVER PEROXISOMES. 610 (1997) (0)
- Asymmetric dimethylarginine-induced oxidative damage leads to cerebrovascular dysfunction (2021) (0)
- Interleukin-17 exacerbates tumor necrosis Factor-α induced apoptotic cell death of oligodendrocytes (148.8) (2011) (0)
- PTW11 Poster Session 11 ‐ Microglia, the blood brain barrier and neuroinflammation (2006) (0)
- Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy (2015) (0)
- Abstract TP101: Inhibition of S-nitrosoglutathione Reductase Improves Stroke Outcomes and Stimulates Functional Recovery in an Aged Mouse Model of Stroke (2020) (0)
- Lovastatin in combination with metformin provides neuroprotection in experimental animal model of multiple sclerosis (P5195) (2013) (0)
- Lovastatin exhibits synergy with Vitamin D hormone to confer protection from experimental autoimmune encephalomylitis (148.5) (2011) (0)
- DIFFERENTIAL EFFECTS OF ALUMINUM AND LITHIUM ON LPS AND A β‐(25–35) INDUCED INOS GENE EXPRESSION IN GLIA AND IN TAU HYPER‐PHOSPHORYLATION, AND ON NEURITE INHIBITION. (2007) (0)
- Peroxisomal fatty acyl-coa oxidase gene disruption causes defective peroxisome assembly in hepatocytes with severe microvesicular steatosis, cell death and hepatocellular proliferation in mouse liver (1996) (0)
- Tumor Necrosis Factor‐[Alpha] regulates lactosylceramide synthesis via activation of Protein Kinase C: A novel function of Gi‐linked sphingosine‐1‐phosphate receptor (2007) (0)
- N-acetylcysteine (NAC) reverses the alterations in antioxidant enzymes seen in the reduced uterine perfusion pressure model (RUPP) of preeclampsia (2006) (0)
- Abstract 2741: S-Nitrosoglutathione Increases Benefit of Motor Exercise on Functional Recovery and Stimulates Neurorepair Mechanisms Following Experimental Stroke in Rats (2012) (0)
- Poster Session BP9: Multiple Sclerosis, EAE (2004) (0)
- Liver Peroxisomes and Fatty acids in Endotoxemia (2003) (0)
- Endotoxin treatment alters the activity of peroxisomal enzymes (1993) (0)
- Abstract 12: S-Nitrosylation Invokes Functional Recovery from Experimental Stroke through the Hypoxia-inducible Factor-1 alpha/Vascular Endothelial Growth Factor Pathway (2014) (0)
- Endogenous Nitric Oxide Carrier S-nitrosoglutathione Attenuates Experimental Autoimmune Encephalomyelitis by Maintaining a Fine Balance between Th1/Th2 Immune Responses (2007) (0)
- Endogenous Nitric Oxide Carrier S-nitrosoglutathione Attenuates Experimental Autoimmune Encephalomyelitis by Maintaining a Fine Balance between Th1/Th2 Immune Responses (131.32) (2007) (0)
- Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats (2015) (0)
- BIOCHEMICAL FEATURES OF A PATIENT WITH ZELLWEGER-LIKE SYNDROME WITH NORMAL PTS-1 AND PTS-2 PEROXISOMAL PROTEIN IMPORT SYSTEMS: A NEW PEROXISOMAL DISEASE. ♦ 626 (1997) (0)
- S-nitrosoglutathione (GSNO) improves cognitive function in a rat model of chronic cerebral hypoperfusion: Vasoprotective and anti-amyloidogenic role of GSNO (2012) (0)
- The role of inflammatory mediators in the pathophysiology of X‐ALD disease (2008) (0)
- FATPY ACID METABOLISM IN REYE'S SYNDROME (1987) (0)
- Multiple intrapartum insults at term: A model of neurodevelopmental injury (2006) (0)
- Lovastatin induced cytokine-mediated inducible nitric oxide synthase (INOS) expression in brain transformed cell lines (2008) (0)
- Abstract TP133: GSNO Pre- and Post-Conditioning Blocks Blood-Brain Barrier Disruption and Improves Endothelial Function in a Mouse Model of Cerebral Ischemia and Reperfusion (2019) (0)
- Endogenous S-Nitrosothiol Induced hypertrophic Astrogliosis has potential to maintain CNS homeostasis under pathological Conditions (72.8) (2012) (0)
- Lysine acetylation: a new protein modification in PPAR‐alpha agonist induced peroxisomes (2008) (0)
- Potential Role of Nitrobiolome in Autoimmune Disease: Efficacy of GSNO in EAE. (2017) (0)
- Therapeutic efficacy of statins and AICAR in mitochondrial dysfunction in EAE (2016) (0)
- The role of complement in spinal cord injury (2007) (0)
- Corticosteroid Responsiveness of Cytokine Airway Inflammation in Mice and Inhibits Social Stress Enhances Allergen-Induced (2009) (0)
- TISSUE DIFFERENCES IN ANTIOXIDANT ENZYME GENE EXPRESSION IN RESPONSE TO ENDOTOXIN. • 297A (1996) (0)
- PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version (2005) (0)
- INCREASED ENDOTHELIN-1 PRODUCTION DURING COLD ISCHEMIA IN STEATOTIC AND NONFUNCTIONAL HUMAN LIVER ALLOGRAFTS MAY INDICATE ENHANCED SUSCEPTIBILITY TO ISCHEMIA-REPERFUSION INJURY (1998) (0)
- The effects of treatment with N-acetylcysteine (NAC) in a rat model of preeclampsia (2004) (0)
- Abstract TMP115: Inhibition Of S-nitrosoglutathione Reductase Mitigates The Acute Injury In A Mouse Model Of Stroke (2023) (0)
- Oral Presentations OR3: Molecular Mechanisms of Neuroinflammation‐Neurodegeneration (2004) (0)
- Reductase Inhibitor for Multiple Sclerosis 3-Hydroxy-3-Methylglutaryl Coenzyme A Potential Targets of (2013) (0)
- 531: N-acetylcysteine prevents preterm birth by attenuating the LPS-induced expression of contractile associated proteins in an animal model forpreterm birth (2009) (0)
- N‐ACETYLCYSTEINE (NAC) REVERSES ALTERATIONS IN ANGIOGENIC FACTORS IN THE REDUCED UTERINE PERFUSION PRESSURE MODEL (RUPP) OF PREECLAMPSIA (2007) (0)
- LOW DOSE ZIDOVUDINE (ZDV) REDUCES MEDIUM AND LONG CHAIN FATTY ACID OXIDATION IN PREGNANT AND NEONATAL RATS. † 1033 (1996) (0)
- Abstract WP113: Induced Pluripotent Stem Cells Derived Neurons Ideally Serve as a Human Stroke Model of Neuronal Damage and Neuroprotective Intervention (2017) (0)
- Kupffer Cells Modulate the Peroxisomal Enzymes in Rat Liver. † 174 (1997) (0)
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What Schools Are Affiliated With Inderjit Singh?
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