Inger Sandlie
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Norwegian molecular biologist
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Why Is Inger Sandlie Influential?
(Suggest an Edit or Addition)According to Wikipedia, Inger Sandlie is a Norwegian molecular biologist. She took her dr.philos. degree in biochemistry at the University of Bergen, and was a post-doctoral fellow at the Johns Hopkins University. She was hired at the University of Oslo in 1988, and is now a professor at the Section for Biochemistry and Molecular Biology. She is a fellow of the Norwegian Academy of Science and Letters.
Inger Sandlie's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Therapeutic antibodies for human diseases at the dawn of the twenty-first century (2003) (551)
- The Neonatal Fc Receptor (FcRn): A Misnomer? (2019) (224)
- Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential (2011) (221)
- Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics (2015) (188)
- Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8−CD11b+ dendritic cells (2011) (187)
- Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding* (2009) (167)
- Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor (2012) (157)
- The structural requirements for complement activation by IgG: does it hinge on the hinge? (1995) (152)
- Aglycosylated IgG variants expressed in bacteria that selectively bind FcγRI potentiate tumor cell killing by monocyte-dendritic cells (2009) (151)
- The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery. (2015) (137)
- Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells. (1997) (126)
- The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH‐dependent binding to albumin (2006) (125)
- Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding* (2014) (119)
- The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics. (2009) (119)
- Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease (2011) (99)
- Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies (2018) (97)
- Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry. (1998) (91)
- Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. (2015) (90)
- Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells. (2005) (83)
- Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury (2017) (74)
- TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity (2015) (68)
- Enhancement of Complement Activation and Cytolysis of Human IgG3 by Deletion of Hinge Exons (1990) (68)
- DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells. (2006) (68)
- Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity. (2013) (66)
- Monoclonal antibodies produced by muscle after plasmid injection and electroporation. (2004) (65)
- Polymeric human Fc-fusion proteins with modified effector functions (2011) (64)
- Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation. (2000) (63)
- The Carboxyl-terminal Domains of IgA and IgM Direct Isotype-specific Polymerization and Interaction with the Polymeric Immunoglobulin Receptor* (2002) (62)
- TRIM21—From Intracellular Immunity to Therapy (2019) (60)
- Effect of the IgM and IgA secretory tailpieces on polymerization and secretion of IgM and IgG. (1996) (60)
- Single-chain Variable Fragment Albumin Fusions Bind the Neonatal Fc Receptor (FcRn) in a Species-dependent Manner (2013) (59)
- Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells (1999) (59)
- Structural requirements for incorporation of J chain into human IgM and IgA. (2000) (59)
- Identification of Residues in the Cμ4 Domain of Polymeric IgM Essential for Interaction with Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1)1 (2008) (56)
- Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease. (2019) (56)
- A human endothelial cell-based recycling assay for screening of FcRn targeted molecules (2018) (53)
- Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions (2015) (52)
- Polymerization of IgA and IgM: roles of Cys309/Cys414 and the secretory tailpiece. (1999) (51)
- Complement C4 Prevents Viral Infection through Capsid Inactivation (2019) (50)
- Solution conformation of wild-type and mutant IgG3 and IgG4 immunoglobulins using crystallohydrodynamics: possible implications for complement activation. (2007) (49)
- Differential Segmental Flexibility and Reach Dictate the Antigen Binding Mode of Chimeric IgD and IgM: Implications for the Function of the B Cell Receptor1 (2004) (48)
- The influence of the hinge region length in binding of human IgG to human Fcgamma receptors. (1998) (47)
- Efficient Delivery of T Cell Epitopes to APC by Use of MHC Class II-Specific Troybodies1 (2002) (46)
- Antibody dependent cell-mediated cytotoxicity induced by chimeric mouse-human IgG subclasses and IgG3 antibodies with altered hinge region. (1992) (45)
- Recombinant expression of polymeric IgA: incorporation of J chain and secretory component of human origin (1999) (45)
- Structural Difference in the Complement Activation Site of Human IgG1 and IgG3 (2009) (44)
- The effect of caffeine on cell growth and metabolism of thymidine in Escherichia coli. (1980) (43)
- A Practical Approach to T-Cell Receptor Cloning and Expression (2011) (43)
- Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions. (2013) (42)
- Expanding the Versatility of Phage Display II: Improved Affinity Selection of Folded Domains on Protein VII and IX of the Filamentous Phage (2011) (41)
- Dissection of the Neonatal Fc Receptor (FcRn)-Albumin Interface Using Mutagenesis and Anti-FcRn Albumin-blocking Antibodies* (2014) (41)
- Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation (2013) (40)
- Structural requirements for the interaction of human IgM and IgA with the human Fcα/μ receptor (2009) (40)
- Interaction with Both Domain I and III of Albumin Is Required for Optimal pH-dependent Binding to the Neonatal Fc Receptor (FcRn)* (2014) (40)
- Human IgG isotype‐specific amino acid residues affecting complement‐mediated cell lysis and phagocytosis (1994) (39)
- Human and mouse albumin bind their respective neonatal Fc receptors differently (2018) (39)
- FcRn binding properties of an abnormal truncated analbuminemic albumin variant. (2010) (38)
- T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation. (2001) (38)
- C1q binding to chimeric monoclonal IgG3 antibodies consisting of mouse variable regions and human constant regions with shortened hinge containing 15 to 47 amino acids (1989) (38)
- Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues (2008) (36)
- One disulfide bond in front of the second heavy chain constant region is necessary and sufficient for effector functions of human IgG3 without a genetic hinge. (1994) (36)
- The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: Implications for peptide vaccination (2001) (36)
- An intact C-terminal end of albumin is required for its long half-life in humans (2020) (34)
- The cytoplasmic tail of invariant chain modulates antigen processing and presentation (2003) (33)
- Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells. (1997) (33)
- Chimeric mouse human IgG3 antibodies with an IgG4‐like hinge region induce complement‐mediated lysis more efficiently than IgG3 with normal hing (1991) (32)
- Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications (2015) (32)
- TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity (2016) (32)
- Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life* (2012) (31)
- Targeting the MHC Ligandome by Use of TCR-Like Antibodies (2019) (31)
- A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance. (2013) (31)
- Activation of complement by an IgG molecule without a genetic hinge (1993) (31)
- A strategy for bacterial production of a soluble functional human neonatal Fc receptor. (2008) (28)
- Next generation phage display by use of pVII and pIX as display scaffolds. (2012) (28)
- Antibody-antigen kinetics constrain intracellular humoral immunity (2016) (28)
- Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization. (2016) (27)
- Expanding the Versatility of Phage Display I: Efficient Display of Peptide-Tags on Protein VII of the Filamentous Phage (2011) (26)
- An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics (2020) (26)
- Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA (2010) (26)
- Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells (2012) (22)
- CORRECTION: Therapeutic antibodies for human disease at the dawn of the twenty-first century (2003) (22)
- Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation. (2000) (22)
- Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display (2013) (21)
- MHC class II loading of high or low affinity peptides directed by Ii/peptide fusion constructs: implications for T cell activation. (2003) (20)
- FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity (2020) (20)
- Identification of a Polymeric Ig Receptor Binding Phage-displayed Peptide That Exploits Epithelial Transcytosis without Dimeric IgA Competition* (2006) (19)
- DeltaPhage—a novel helper phage for high-valence pIX phagemid display (2012) (18)
- Functional phage display of two murine α/β T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance (2007) (18)
- Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype. (2008) (17)
- Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling. (1995) (17)
- Multivalent pIX phage display selects for distinct and improved antibody properties (2016) (16)
- Phage Display and Selection of Protein Ligands (2015) (16)
- A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions. (2017) (16)
- Selection and Characterization of Cyclic Peptides that Bind to a Monoclonal Antibody Against Meningococcal L3,7,9 lipopolysaccharides (2004) (16)
- Human Secretory IgM Antibodies Activate Human Complement and Offer Protection at Mucosal Surface (2017) (16)
- IgM secretory tailpiece drives multimerisation of bivalent scFv fragments in eukaryotic cells. (1998) (16)
- Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling. (1996) (15)
- Activation of complement by an IgG molecule without a genetic hinge (1993) (15)
- A receptor-mediated mechanism to support clinical observation of altered albumin variants. (2007) (15)
- Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region. (2002) (15)
- The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fcγ receptors, but the heavy chains must be disulfide bonded (1993) (14)
- A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells (2006) (14)
- Characterization of an FcγRI-binding peptide selected by phage display (2006) (14)
- Human IgG3 can adopt the disulfide bond pattern characteristic for IgG1 without resembling it in complement mediated cell lysis. (1993) (13)
- Functional in vitro studies of recombinant human immunoglobulin G and immunoglobulin A anti‐D (2007) (13)
- Recombinant chimeric OKT3 scFv IgM antibodies mediate immune suppression while reducing T cell activation in vitro (2001) (12)
- Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life (2022) (12)
- T-cell receptor tau delta +/CD3+4-8-T- cell acute lymphoblastic leukemias: a distinct subgroup of leukemias in children. A report of five cases. (1991) (11)
- Mechanism of inhibition of thymidine kinase from Escherichia coli by caffeine (1980) (11)
- Troybodies and pepbodies. (2001) (11)
- Animal models for evaluation of albumin-based therapeutics (2018) (11)
- Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system (2018) (10)
- In vitro assessment of recombinant, mutant immunoglobulin G anti‐D devoid of hemolytic activity for treatment of ongoing hemolytic disease of the fetus and newborn (2008) (10)
- Selection of Nanobodies that Target Human Neonatal Fc Receptor (2013) (10)
- In vitro functional test of two subclasses of an anti‐RhD antibody produced by transient expression in COS cells (2006) (9)
- Engineering monoclonal antibodies to determine the structural requirements for complement activation and complement mediated lysis. (1991) (8)
- Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes (2005) (8)
- Processing of an Antigenic Sequence from IgG Constant Domains for Presentation by MHC Class II1 (2008) (8)
- Identification of a High Affinity FcγRIIA-binding Peptide That Distinguishes FcγRIIA from FcγRIIB and Exploits FcγRIIA-mediated Phagocytosis and Degradation* (2009) (7)
- Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins (2010) (7)
- 'Troy-bodies': antibodies as vector proteins for T cell epitopes. (2001) (7)
- Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo (2021) (7)
- The neonatal Fc receptor in mucosal immune regulation (2020) (7)
- Phage Display Engineered T Cell Receptors as Tools for the Study of Tumor Peptide–MHC Interactions (2014) (7)
- Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge (2022) (6)
- The expression of the Escherichia coli uvrA gene in human cells. (1988) (6)
- A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation (2021) (6)
- Mechanism of caffeine‐induced inhibition of DNA synthesis in Escherichia coli (1983) (6)
- Induction of central T cell tolerance: Recombinant antibodies deliver peptides for deletion of antigen‐specific CD4+8+ thymocytes (2005) (6)
- Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance. (2007) (6)
- Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes. (2008) (6)
- Complement-mediated lysis of cultured osteosarcoma cell lines using chimeric mouse/human TP-1 IgG1 and IgG3 antibodies (1999) (5)
- The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure. (2014) (4)
- “Troy-bodies”: Recombinant Antibodies that Target T Cell Epitopes to Antigen Presenting Cells (2001) (4)
- Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life (2022) (4)
- Engineering of the Fc Region for Improved PK (FcRn Interaction) (2010) (4)
- Effect of caffeine on nucleotide pools in Escherichia coli. (1982) (4)
- A TRAV26‐1‐encoded recognition motif focuses the biased T cell response in celiac disease (2019) (3)
- CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses. (2012) (3)
- Characterization of an FcgammaRI-binding peptide selected by phage display. (2006) (3)
- Balanced expression of single subunits in a multisubunit protein, achieved by cell fusion of individual transfectants. (2002) (2)
- A Public T cell Receptor Recognized by a Monoclonal Antibody Specific for the D‐J Junction of the β‐chain (2013) (2)
- Erratum: Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Location of lysine residues and implications for radiolabeling (Nuclear Medicine and Biology (1995) 22 (765- 771)) (1999) (1)
- Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies (2019) (1)
- Shapes TCR Usage in Celiac Disease Posttranslational Modification of Gluten (2011) (1)
- Enhanced albumins and albumin fusion technology: tuning circulatory half-life with Novozymes Albufuse ® Flex to meet medical needs (2012) (1)
- The Influence of FcRn on Albumin-Fused and Targeted Drugs (2016) (1)
- THE MHC CLASS I-RELATED FCRN PROTECTS ALBUMIN AND IGG FROM DEGRADATION: IMPLICATIONS FOR DEVELOPMENT AND EVALUATIONS OF NEW DIAGNOSTICS AND THERAPEUTICS (2008) (1)
- A human endothelial cell-based recycling assay for screening of FcRn targeted molecules (2018) (1)
- Affinity maturation of TCR-like antibodies using phage display guided by structural modeling (2022) (1)
- The Influence of FcRn on Albumin-Fused and Targeted Drugs (2016) (1)
- Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design (2011) (0)
- Microsoft Word-Manuscript3JBC (2009) (0)
- Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses. (2021) (0)
- Edinburgh Research Explorer Identification of Residues in the C4 Domain of Polymeric IgM Essential for Interaction with Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1)1 (2017) (0)
- Engineering of aglycosylated antibody Fc for selective binding to Fc gamma receptors and effector function (2008) (0)
- Modèle pharmacocinétique animal (2014) (0)
- An intact C-terminal end of albumin is required for its long half-life in humans (2020) (0)
- Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity (2017) (0)
- Human and mouse albumin bind their respective neonatal Fc receptors differently (2018) (0)
- Recombinant anti-human and anti-porcine CD14 antibodies (2012) (0)
- Flexibility and Geometry Small Immune Complexes: A Role for Hinge Mutants, IgM, IgE, and IgA2, to Form Comparisons of the Ability of Human IgG3 (1998) (0)
- Mechanism of caffeine-induced inhibition Escherichia coli (2001) (0)
- Receptor ( FcRn ) pH-dependent Binding to the Neonatal Fc Albumin Is Required for Optimal Interaction with Both Domain I and III of Protein Structure and Folding : (2014) (0)
- Recombinant Antibodies for Immunotherapy: Extending Antibody Fragment Half-Lives with Albumin (2009) (0)
- P150 THE HUMAN FC GAMMA RIIA H131 POLYMORPHISM IS A NEONATAL RECEPTOR (FCRN)-DEPENDENT HIGH RESPONDER VARIANT IN INFLAMMATORY BOWEL DISEASE (2019) (0)
- Affinity-engineered human antibodies detect celiac disease gluten pMHC complexes and inhibit T-cell activation (2019) (0)
- Erratum: Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins (European Journal of Immunology (2000) 30:12 (3591-3597)) (2001) (0)
- Pig and Human Models of Inflammation Antibodies for Therapeutic Intervention in Chimeric Anti-CD14 IGG2/4 Hybrid (2013) (0)
- P150 THE HUMAN FC GAMMA RIIA H131 POLYMORPHISM IS A NEONATAL RECEPTOR (FCRN)-DEPENDENT HIGH RESPONDER VARIANT IN INFLAMMATORY BOWEL DISEASE. (2019) (0)
- Heterodimers MHC class II soluble functional stabilized by disulfide bonds (2011) (0)
- D. Plan for Second Five-year Period, including Exit Strategy, Cir, 179573 A. Research Plan (0)
- CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4 1 T-cell responses (2012) (0)
- [DNA probes. An important aid in the diagnosis of lymphoma]. (1987) (0)
- The role of ROS in the etiology of cancer and in ageing (2012) (0)
- animal pharmacokinetic model (2014) (0)
- HALF-LIFE EVALUATION OF IMPLICATIONS FOR IN VIVO ( FcRn ) in a Species-dependent Manner : Fusions Bind the Neonatal Fc Receptor Single-chain Variable Fragment Albumin Protein Structure and Folding : (2013) (0)
- T Cell Recognition of the Dominant I-Ak–Restricted Hen Egg Lysozyme Epitope (2001) (0)
- Activation ofcomplement byhumanIgG1andhumanIgG3antibodies against the humanleucocyte antigen CD52 (1998) (0)
- Function of the B Cell Receptor Chimeric IgD and IgM: Implications for the Dictate the Antigen Binding Mode of Differential Segmental Flexibility and Reach (2004) (0)
- IgG3 antibody with shortened hinge-region and a komplementaktivierungstest (1990) (0)
- Antibody Fusion Proteins edited by S.M. Chamow and A. Ashkenazi (2000) (0)
- Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer. (2022) (0)
- [The T-cell antigen receptor. Structure, gene rearranging and function]. (1987) (0)
- Engineering of human albumin for enhanced half-life and transmucosal 1 delivery of protein-based biologics 2 (2020) (0)
- Neonatal FC Receptor Cooperates with Classical FC Gamma Receptors to Control Inflammatory Bowel Disease through Regulating Immune Complex Processing (2017) (0)
- Binding of albumin-fusions to FcRn (2013) (0)
- Cover Picture: Eur. J. Immunol. 4/09 (2009) (0)
- Antibody Variable Sequences Have a Pronounced Effect on Cellular Uptake, Transport and Plasma Half-Life (2021) (0)
- Pepbodies and Troybodies (2002) (0)
- Class II IgG Constant Domains for Presentation by Processing of an Antigenic Sequence from and (2008) (0)
- Cell Receptor Implications for the Function of the B Mode of Chimeric IgD and IgM: Reach Dictate the Antigen Binding Differential Segmental Flexibility and (2010) (0)
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