Ingolf Cascorbi
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(Suggest an Edit or Addition)Ingolf Cascorbi's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. (2000) (2528)
- Metabolic gene polymorphism frequencies in control populations. (2001) (915)
- Frequency of single nucleotide polymorphisms in the P‐glycoprotein drug transporter MDR1 gene in white subjects (2001) (747)
- A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. (1996) (374)
- Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. (1996) (372)
- Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity. (1995) (354)
- Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. (2006) (341)
- Modulation of steady‐state kinetics of digoxin by haplotypes of the P‐glycoprotein MDR1 gene (2002) (329)
- Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. (2003) (327)
- Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. (2002) (326)
- Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden (2005) (298)
- Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population (2003) (248)
- Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer. (2003) (220)
- Pharmacogenetics of cytochrome P4502D6: genetic background and clinical implication (2003) (214)
- The effects of the human MDR1 genotype on the expression of duodenal P‐glycoprotein and disposition of the probe drug talinolol (2002) (212)
- CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis. (2003) (211)
- MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier (2007) (203)
- Should We Use N-Acetyltransferase Type 2 Genotyping To Personalize Isoniazid Doses? (2005) (191)
- Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism. (2000) (186)
- CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. (2002) (185)
- P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations. (2011) (184)
- Functional Gene Variants of CYP3A4 (2014) (181)
- Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes (2002) (175)
- Substantially reduced risk of cancer of the aerodigestive tract in subjects with variant--463A of the myeloperoxidase gene. (2000) (169)
- Carbamazepine regulates intestinal P‐glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans (2004) (161)
- The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease. (2004) (160)
- Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. (2017) (157)
- Drug interactions--principles, examples and clinical consequences. (2012) (155)
- MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. (2002) (152)
- VARIABLE EXPRESSION OF MRP2 (ABCC2) IN HUMAN PLACENTA: INFLUENCE OF GESTATIONAL AGE AND CELLULAR DIFFERENTIATION (2005) (149)
- Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. (1996) (145)
- Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles (2014) (141)
- High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes. (1998) (138)
- Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants. (2001) (134)
- Transient Receptor Potential Channel Polymorphisms Are Associated with the Somatosensory Function in Neuropathic Pain Patients (2011) (133)
- CYP1A1 T3801 C polymorphism and lung cancer: A pooled analysis of 2,451 cases and 3,358 controls (2003) (129)
- CYP3A5 Genotype Markedly Influences the Pharmacokinetics of Tacrolimus and Sirolimus in Kidney Transplant Recipients (2007) (126)
- Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis. (2011) (123)
- Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance (2014) (121)
- CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects (2004) (120)
- Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies. (2001) (118)
- Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years. (2003) (116)
- Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex (2007) (116)
- Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19 (2005) (104)
- Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1). (1999) (100)
- Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United States) (2003) (100)
- A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: a case-controlled study (1999) (99)
- Intestinal expression of P‐glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate–glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans (2006) (96)
- Arylamine N-acetyltransferase activity in man. (1999) (95)
- Clinical pharmacology in research, teaching and health care: Considerations by IUPHAR, the International Union of Basic and Clinical Pharmacology. (2010) (94)
- Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 −24C>T polymorphism in young and adult patients with epilepsy (2009) (93)
- The ATP-binding Cassette Transporter ABCG2 (BCRP), a Marker for Side Population Stem Cells, Is Expressed in Human Heart (2006) (93)
- Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart. (2003) (91)
- A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics (2016) (91)
- Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol (2008) (91)
- Polymorphisms in the human CYP1A1 gene as susceptibility factors for lung cancer: exon-7 mutation (4889 A to G), and a T to C mutation in the 3′-flanking region (1994) (91)
- Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10. (2001) (90)
- Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms. (2004) (87)
- The Nomenclature, Definition and Distinction of Types of Shock. (2018) (84)
- High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease. (2000) (81)
- MicroRNAs and their relevance to ABC transporters. (2014) (79)
- Down-Regulation of ATP-Binding Cassette C2 Protein Expression in HepG2 Cells after Rifampicin Treatment Is Mediated by MicroRNA-379 (2011) (77)
- Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk. (1999) (77)
- A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1. (2006) (76)
- Molecular Genetics of Cancer Susceptibility (2000) (75)
- Genetic basis of toxic reactions to drugs and chemicals. (2006) (75)
- A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. (2019) (75)
- Pitfalls in N-acetyltransferase 2 genotyping. (1999) (74)
- MicroRNA profiling in K-562 cells under imatinib treatment: influence of miR-212 and miR-328 on ABCG2 expression (2012) (73)
- Decreased Levels of Dopamine D3 Receptor mRNA in Schizophrenic and Bipolar Patients (2004) (71)
- Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function (2011) (71)
- Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-jewish caucasian sample. (2001) (70)
- Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex (2007) (69)
- Pharmacogenetics of ATP-binding cassette transporters and clinical implications. (2010) (69)
- Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens (2007) (68)
- High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma. (2004) (67)
- Polymorphisms in xenobiotic conjugation and disease predisposition. (1998) (67)
- Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study. (2005) (66)
- Impact of Myeloperoxidase and NADPH-Oxidase Polymorphisms in Drug-Induced Agranulocytosis (2004) (63)
- miRNAs as mediators of drug resistance. (2012) (63)
- Hematopoietic stem cell involvement in BCR-ABL1-positive ALL as a potential mechanism of resistance to blinatumomab therapy. (2017) (63)
- Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy. (2004) (62)
- Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1) (2013) (61)
- Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease. (2001) (59)
- Population frequency, mutation linkage and analytical methodology for the Arg16Gly, Gln27Glu and Thr164Ile polymorphisms in the beta2-adrenergic receptor among Turks. (1999) (58)
- Occupational history and genetic N-acetyltransferase polymorphism in urothelial cancer patients of Leverkusen, Germany. (1996) (57)
- Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity. (2000) (57)
- Expression and Localization of P-glycoprotein in Human Heart (2002) (57)
- Antimicrobial peptides and proteins of the horse - insights into a well-armed organism (2011) (56)
- HLA-DRB1*16: 01-DQB1*05 02 is a novel genetic risk factor for flupirtine-induced liver injury (2016) (55)
- Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease. (1999) (54)
- Clinical trial: A novel high‐dose 1 g mesalamine suppository (salofalk) once daily is as efficacious as a 500‐mg suppository thrice daily in active ulcerative proctitis (2010) (54)
- Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry. (2001) (53)
- Myeloperoxidase G-463A polymorphism and lung cancer: A HuGE Genetic Susceptibility to Environmental Carcinogens pooled analysis (2007) (52)
- Functional significance of a hereditary adenine insertion variant in the 5'-UTR of the endothelin-1 gene. (2003) (52)
- Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity. (2009) (50)
- Myeloperoxidase--463A variant reduces benzo[a]pyrene diol epoxide DNA adducts in skin of coal tar treated patients. (2001) (49)
- Determination and allelic allocation of seven nucleotide transitions within the arylamine N‐acetyltransferase gene in the Polish population (1996) (48)
- Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy (2011) (48)
- How to Manage Individualized Drug Therapy: Application of Pharmacogenetic Knowledge of Drug Metabolism and Transport (2000) (48)
- Gender and smoking-related risk reduction of periodontal disease with variant myeloperoxidase alleles (2002) (47)
- Simvastatin does not influence the intestinal P-glycoprotein and MPR2, and the disposition of talinolol after chronic medication in healthy subjects genotyped for the ABCB1, ABCC2 and SLCO1B1 polymorphisms. (2006) (46)
- Effect of levothyroxine administration on intestinal P‐glycoprotein expression: Consequences for drug disposition * (2002) (46)
- Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study (2018) (46)
- Educating European (junior) doctors for safe prescribing. (2007) (46)
- Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus (2015) (45)
- Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey. (2019) (44)
- Identification and Characterization of a Defective CYP3A4 Genotype in a Kidney Transplant Patient With Severely Diminished Tacrolimus Clearance (2014) (44)
- High frequency of CYP1A1 mutations in a Turkish population (1998) (44)
- Paraoxonase 1 mutations in a Turkish population. (1999) (43)
- Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme (2013) (42)
- NAT2*12A (803A-->G) codes for rapid arylamine n-acetylation in humans. (1996) (42)
- The Neurophysiology and Treatment of Motion Sickness. (2018) (40)
- Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease. (2013) (40)
- Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper (2020) (39)
- Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample (2005) (39)
- Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients (2008) (39)
- Elimination half-life of anti-Müllerian hormone. (2012) (38)
- SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients (2015) (38)
- Role of Kozak sequence polymorphism of platelet glycoprotein Ibalpha as a risk factor for coronary artery disease and catheter interventions. (2001) (38)
- OpenVigil—free eyeballs on AERS pharmacovigilance data (2012) (37)
- Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes: no association with myeloperoxidase and cytochrome P4502D6. (2000) (37)
- Endothelial NO Synthase Polymorphisms and Postural Tachycardia Syndrome (2005) (35)
- Interaction of herbal products with prescribed medications: A systematic review and meta‐analysis (2019) (34)
- CYP1A1 mutations 4887A, 4889G, 5639C and 6235C in the Polish population and their allelic linkage, determined by peptide nucleic acid-mediated PCR clamping. (1997) (34)
- Polymorphic enzymes of xenobiotic metabolism as modulators of acquired P53 mutations in bladder cancer. (1996) (33)
- Dysregulation of Mucosal Membrane Transporters and Drug-Metabolizing Enzymes in Ulcerative Colitis. (2019) (33)
- Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population. (1997) (33)
- Pharmacogenetics‐Based New Therapeutic Concepts (2004) (31)
- Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients (2012) (31)
- Co-expression of human cytochrome P4501A1 (CYP1A1) variants and human NADPH-cytochrome P450 reductase in the baculovirus/ insect cell system (2001) (31)
- Meta-analysis on outcome-worsening comorbidities of COVID-19 and related potential drug-drug interactions (2020) (30)
- Genetic variants may play an important role in mRNA–miRNA interaction: evidence for haplotype-dependent downregulation of ABCC2 (MRP2) by miRNA-379 (2014) (30)
- Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic lupus erythematosus. (2002) (29)
- Influence of CYP3A4, CYP3A5, and ABCB1 Genotype and Expression on Budesonide Pharmacokinetics: A Possible Role of Intestinal CYP3A4 Expression (2008) (29)
- Differential Expression and Functionality of TRPA1 Protein Genetic Variants in Conditions of Thermal Stimulation* (2012) (28)
- Interaction of xenobiotics on the glucose-transport system and the Na+/K(+)-ATPase of human skin fibroblasts. (1991) (28)
- Elevated serum leptin in patients with coronary artery disease: no association with the Trp64Arg polymorphism of the β3-adrenergic receptor (2000) (27)
- Reduced procedural risk for coronary catheter interventions in carriers of the coagulation factor VII-Gln353 gene. (2000) (27)
- Implementation and obstacles of pharmacogenetics in clinical practice: An international survey (2019) (27)
- ABC Transporters in Drug‐Refractory Epilepsy: Limited Clinical Significance of Pharmacogenetics? (2010) (26)
- Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine. (2017) (25)
- Endothelial nitric oxide synthase Glu298→Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample (2005) (25)
- Association between the N-acetylation genetic polymorphism and bronchial asthma. (2002) (23)
- Correlation between the lipophilicity of substituted phenols and their inhibition of the Na+/K+-ATPase of Chinese hamster ovary cells. (1989) (23)
- Association of metabolic gene polymorphisms with tobacco consumption in healthy controls (2004) (23)
- Pharmacogenetics and Predictive Testing of Drug Hypersensitivity Reactions (2016) (22)
- Genotype frequencies of selected drug metabolizing enzymes and ABC drug transporters among breast cancer patients on FAC chemotherapy. (2010) (21)
- Pharmacogenomic or ‐epigenomic biomarkers in drug treatment: Two sides of the same medal? (2016) (21)
- The promises of personalized medicine (2010) (20)
- ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding? (2021) (20)
- Effects of a heterogeneous set of xenobiotics on growth and plasma membranes of mammalian and fungal cell cultures. (1993) (20)
- Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method. (2011) (19)
- Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide combination chemotherapy for breast cancer (2014) (19)
- Cyclophosphamide treatment-induced leukopenia rates in ANCA-associated vasculitis are influenced by variant CYP450 2C9 genotypes. (2016) (18)
- 'Comparison of extremes' approach provides evidence against the modifying role of NAT2 polymorphism in lung cancer susceptibility. (2005) (18)
- Genetic determinants of drug-induced agranulocytosis: potential risk of olanzapine? (1999) (18)
- Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure (2004) (17)
- Interaction with functional membrane proteins--a common mechanism of toxicity for lipophilic environmental chemicals? (1991) (17)
- miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model. (2016) (17)
- Length variants of the ABCB1 3'-UTR and loss of miRNA binding sites: possible consequences in regulation and pharmacotherapy resistance. (2016) (17)
- Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population (2019) (16)
- The β3-adrenergic receptor Trp64Arg mutation is not associated with coronary artery disease (2001) (16)
- MicroRNA-212/ABCG2-axis contributes to development of imatinib-resistance in leukemic cells (2017) (16)
- Pharmacogenomics of heart failure -- focus on drug disposition and action. (2004) (16)
- TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL REGULATION OF DUODENAL P-GLYCOPROTEIN AND MRP2 IN HEALTHY HUMAN SUBJECTS AFTER CHRONIC TREATMENT WITH RIFAMPIN AND CARBAMAZEPINE. (2019) (16)
- Drug-Induced Agranulocytosis: Impact of Different Fcγ Receptor Polymorphisms? (2005) (16)
- Association of NAT 1 and NAT 2 Polymorphisms to Urinary Bladder Cancer : Significantly Reduced Risk in Subjects with NAT 1 * 10 1 (2001) (16)
- A1166C polymorphism of the angiotensin II type 1 receptor gene and risk of adverse events after coronary catheter interventions. (2000) (15)
- Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia (2021) (15)
- Challenges in pharmacogenetics (2013) (15)
- Drug Hypersensitivity. (2018) (15)
- Endothelial nitric oxide synthase Glu(298)-->Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample. (2005) (15)
- Peptide nucleic acid-mediated polymerase chain reaction clamping allows allelic allocation of CYP1A1 mutations. (1997) (14)
- A clinical trial on absorption and N‐acetylation of oral and rectal mesalazine (2007) (14)
- Beta 2-adrenergic receptor polymorphism and susceptibility to primary congenital and primary open angle glaucoma (2003) (14)
- Interaction of CA repeat polymorphism of the endothelial nitric oxide synthase and hyperhomocysteinemia in acute coronary syndromes: evidence of gender-specific differences (2003) (14)
- Short Report: TRPV1-polymorphism 1911 A>G alters capsaicin-induced sensory changes in healthy subjects (2017) (13)
- Major increase of quetiapine steady-state plasma concentration following co-administration of clarithromycin: confirmation of the pharmacokinetic interaction potential of quetiapine. (2008) (13)
- Expression differences of miR-142-5p between treatment-naïve chronic myeloid leukemia patients responding and non-responding to imatinib therapy suggest a link to oncogenic ABL2, SRI, cKIT and MCL1 signaling pathways critical for development of therapy resistance (2020) (13)
- Metabolic Gene Polymorphism Frequencies in Control Populations 1 (2001) (13)
- Epigenetics in Drug Response (2016) (13)
- Influence of an Insertion Variant in the 5′UTR of the Endothelin-1 Gene on Orthostatic Intolerance (2005) (13)
- Clinical implementation of pharmacogenetics: a nonrepresentative explorative survey to participants of WorldPharma 2010. (2011) (13)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2005) (12)
- Pharmacovigilance‐based drug repurposing: The search for inverse signals via OpenVigil identifies putative drugs against viral respiratory infections (2021) (12)
- Risk of coronary artery disease as influenced by variants of the human endothelin and endothelin-converting enzyme genes (2007) (12)
- Identification and functional analysis of genetic variants of the human &bgr;-glucuronidase in a German population sample (2005) (12)
- Expression of N-acetyltransferases in Periodontal Granulation Tissue (2002) (12)
- Overlapping effects of genetic variation and epigenetics on drug response: challenges of pharmacoepigenomics. (2013) (11)
- Significance of Pharmacogenomics in Precision Medicine (2018) (10)
- Progress in Pharmacogenomics: Bridging the Gap From Research to Practice (2014) (10)
- No benefit of 3,4-diaminopyridine in essential tremor: A placebo-controlled crossover study (2006) (10)
- High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from subjects with combined CYP1A1 Mspl/Mspl and GSTM1*0/*0 genotypes (1997) (10)
- MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2 (2018) (10)
- Alternative Polyadenylation of ABC Transporters of the C-Family (ABCC1, ABCC2, ABCC3) and Implications on Posttranscriptional Micro-RNA Regulation (2019) (10)
- Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important? (2017) (10)
- Retinoic acid–induced survival effects in SH‐SY5Y neuroblastoma cells (2018) (10)
- P XVI A.8 High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from subjects with combined CYP1A1 MspI/MspI-GSTM1*0/*0 genotypes (1997) (9)
- The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients (2020) (9)
- Opportunities and limitations: the value of pharmacogenetics in clinical practice. (2014) (9)
- Drug‐Drug‐Gene Interactions: A Call for Clinical Consideration (2021) (9)
- Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians (2014) (9)
- The beta3-adrenergic receptor Trp64Arg mutation is not associated with coronary artery disease. (2001) (9)
- Hyperhomocysteinaemia and adverse events complicating coronary catheter interventions. (2000) (8)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2005) (8)
- Plan S: A threat to quality of science? (2019) (8)
- A phase I pharmacokinetic study of matuzumab in combination with paclitaxel in patients with EGFR-expressing advanced non-small cell lung cancer (2013) (8)
- Co-trimoxazole-induced liver and renal failure (2000) (8)
- SIGMA-1 Receptor Gene Variants Affect the Somatosensory Phenotype in Neuropathic Pain Patients. (2019) (8)
- Activation of the cell membrane angiotensin AT2 receptors in human leiomyosarcoma cells induces differentiation and apoptosis by a PPARγ - dependent mechanism. (2017) (8)
- Advances and challenges in hereditary cancer pharmacogenetics (2017) (8)
- Pioglitazone induces cell growth arrest and activates mitochondrial apoptosis in human uterine leiomyosarcoma cells by a peroxisome proliferator-activated receptor γ-independent mechanism (2016) (7)
- HLA-A*33:01 is strongly associated with drug-induced liver injury (DILI) due to terbinafine and several other unrelated compounds (2015) (7)
- Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults. (2010) (7)
- Genotype and phenotype relationship in drug metabolism. (2007) (7)
- Neurodegenerative effects of azithromycin in differentiated PC12 cells (2017) (7)
- Untersuchung zur klinischen Relevanz der Acetyliererphänotypisierung bei 196 Urotheltumorpatienten (1997) (6)
- Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis (2006) (6)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2006) (6)
- Linking pre-existing biorepositories for medical research: the PopGen 2.0 Network (2019) (6)
- Inflammation: Treatment Progress and Limitations (2017) (5)
- A functional serotonin transporter (SLC6A4) polymorphism modifies the association of smoking and diabetes with asymptomatic carotid atherosclerosis (2005) (5)
- The platelet glycoprotein Ia C807T polymorphism as risk factor for coronary catheter interventions. (2000) (5)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2005) (5)
- Analgetika und Koanalgetika: Anwendung, gesetzliche Grundlagen und Probleme (2013) (5)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2005) (5)
- Identification of twelve polymorphisms in the endothelin-1 gene by use of fluorescently labeled oligonucleotides and PCR with restriction fragment polymorphism analysis. (2004) (5)
- Kardiopulmonale Reanimation—CPR (2006) (4)
- Correction: A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics (2017) (4)
- The Pharmacogenetics of Immune-Modulating Therapy. (2018) (4)
- Dietary induction and reversal of obesity and insulin resistance is associated with changes in Fgf21 DNA methylation in liver of mice (2021) (4)
- Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation (2022) (3)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2004) (3)
- Pharmacogenomics in acute coronary syndrome (2008) (3)
- The Uncertainties of Metamizole Use (2021) (3)
- Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells (2017) (3)
- Influence of doxorubicin on gene expression and protein pattern in HeLa cells. (2004) (3)
- Safe and effective medicines for all: is personalized medicine the answer? (2010) (3)
- Dosisanpassung bei Leberinsuffizienz (2003) (3)
- Conference Scene: Pharmacogenomics at the second PharmSciFair 2009: adverse drug reactions and clinical implementation. (2009) (3)
- Germline variants in cancer therapy (2019) (3)
- A Polymorphism in Exon 7 of Human CYP 1 AJ : Population Frequency , Mutation Linkages , and Impact on Lung Cancer Susceptibility 1 (3)
- Targeting gene expression during the early bone healing period in the mandible: A base for bone tissue engineering. (2015) (3)
- Stand der Pharmakogenomik und deren zukünftige Rolle für die Arzneitherapie (2002) (3)
- Effects of a heterogeneous set of xenobiotics on RNA synthesis of yeast cells. (1995) (3)
- Limited Impact of 6-Mercaptopurine on Inflammation-Induced Chemokines Expression Profile in Primary Cultures of Enteric Nervous System (2021) (2)
- Involvement of medical students in a surgery congress: impact on learning motivation, decision-making for a career in surgery, and educational curriculum (2021) (2)
- High‐dose spironolactone lacks effectiveness in treatment of fibromyalgia (RCT) (2021) (2)
- P‐glycoprotein (MDR1/ABCB1) (2013) (2)
- Implication of arylamine N-acetyltransferase (NAT2) polymorphism on levels of tumour markers CEA, AFP, CA 125, CA 19.9, and CA 15.3 (1999) (2)
- Pharmakogenetik: Aktueller Stand – Fakten und Fiktionen (2017) (2)
- Pharmakogenetik (2017) (2)
- Stellungnahme der Sektion „Schock“ der DIVI zur Schocklage (2012) (2)
- Subject Index Vol. 50, 2004 (2004) (2)
- Arzneimitteltransporter: Bedeutung für die Klinik (2003) (2)
- Pharmacological Treatment of Pain: Future Trends and Novel Insights (2015) (2)
- Association between breast cancer and estrogen receptor gene polymorphism PVU II. (2006) (2)
- ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells. (2021) (2)
- Conference Scene: 5th Anniversary Meeting of the European Research Network Pharmacogenetics/Pharmacogenomics (2012) (2)
- [Status of pharmacogenomics and its future role in drug therapy]. (2002) (1)
- Abstract 5846: Drug resistance in chronic myeloid leukemia: Impact of methylation on gene expression in imatinib and nilotinib resistance (2018) (1)
- The G protein subunit beta3 and early complications after coronary catheter interventions. (2000) (1)
- Neue Fortbildungsreihe zur Notfallpharmakotherapie (2020) (1)
- Gene‐environment synergisms in bladder cancer risk: Arylamine n‐acetyltransferase type 2, smoking and occupation (1996) (1)
- Co-trimoxazole-induced liver and renal failure. Case report. (2000) (1)
- Abstracts of the 87th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) with contribution of the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e. V. (AGAH) (2021) (1)
- Pharmacogenetics of Phase II Drug Metabolizing Enzymes (2012) (1)
- Pharmacogenomics in acute coronary syndrome. (2008) (1)
- Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters. (2021) (1)
- Progress and Challenges in Pharmacogenomics (2021) (1)
- Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important? (2017) (1)
- Gliflozins for the Treatment of Congestive Heart Failure and Renal Failure in Type 2 Diabetes. (2021) (1)
- POLAR – „POLypharmazie, Arzneimittelwechselwirkungen und Risiken“ – wie können Daten aus der stationären Krankenversorgung zur Beurteilung beitragen? (2022) (1)
- [Hypoglycemic risk of insulinotropic drugs]. (2009) (1)
- 4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation. (2019) (1)
- Identification of putative drugs against viral respiratory infections by the pharmacovigilance analysis tool OpenVigil 2 (2020) (0)
- Contents Vol. 50, 2004 (2004) (0)
- DMD055202 718..725 (2014) (0)
- 4th ESPT summer school: precision medicine and personalised health. (2019) (0)
- Longitudinal analysis of the development of hepatic insulin resistance in diet-induced obese mice (2018) (0)
- N-acetyltransferase 2 and glutathione-S-transferase μ (GSTM1) in bladder cancer patients in an area of former coal, iron and steel industries (1996) (0)
- Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population (2019) (0)
- Pharmacogenetics in the Cardiovascular Field (2002) (0)
- The polymorphic enzymes N-acetyltransferase 2 and glutathione S-transferase M1 In bladder cancer patients (1997) (0)
- Drug interactions - basic information and aspects specific to intensive care medicine (2011) (0)
- Analgetika und Koanalgetika in der (2014) (0)
- Modulation of ABCB1 (MDR1) and ABCC2 (MRP2) expression dependent on genetic polymorphisms in renal cell carcinoma. (2004) (0)
- OV‐A‐2 (2006) (0)
- CRISPR/Cas9-induced knockout reveals the role of ABCB1 in the response to temozolomide, carmustine and lomustine in glioblastoma multiforme. (2022) (0)
- Molekulare Medizin ist Realität : Individuell optimierte Arzneitherapie auf Basis genetischer Tests (1999) (0)
- Pharmacogenomics — Der Weg zur optimalen Therapie? (2003) (0)
- Analgetika und Koanalgetika in der Schmerzmedizin (2019) (0)
- Behandlungsmöglichkeiten in Rettungsdienst und Notaufnahme (2023) (0)
- Analgetika und Koanalgetika in der Schmerztherapie (2015) (0)
- 4th ESPT Conference (2019) (0)
- Pharmakogenetik in der Kardiologie (2007) (0)
- Medikamenten-Pocket Schmerztherapie (2013) (0)
- Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI (2005) (0)
- Polypharmazie – Interaktionen bei älteren Menschen (2022) (0)
- Haemostasis in shock Part 2: physiology of haemostasis (2014) (0)
- Molekulare Pathologie (2000) (0)
- Hypoglykämie bei insulinotropen Substanzen (2009) (0)
- Bedeutung genetischer Polymorphismen für die Suszeptibilität und Therapie von kardiovaskulären Krankheiten (2003) (0)
- P-Glycoprotein Fluorescence Microscopy Signal Correlates to Protein Expression in Human Enterocytes and Clinical Activity Index in Ulcerative Colitis (2009) (0)
- Statement of DIVI Section "Shock" Regarding the Trendelenburg Position (2012) (0)
- Abstracts of the 88th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) (2022) (0)
- IgG- Fcγ- receptor polymorphisms in drug-induced-induced agranulocytosis (2004) (0)
- Challenges in pharmacogenetics (2013) (0)
- The hereditary anchored susceptibility to altered sensory nociception (2011) (0)
- 255 GENETIC POLYMORPHISMS IN TRP CHANNELS ARE ASSOCIATED WITH THE SOMATOSENSORY FUNCTION IN NEUROPATHIC PAIN PATIENTS (2010) (0)
- Elimination half-life of anti-Mullerian hormone in the human (2011) (0)
- University of Dundee Association of Liver Injury From Specific Drugs , or Groups of Drugs , With Polymorphisms in HLA and Other Genes in a Genome-wide Association Study (0)
- Challenges in Neuropharmacology (2019) (0)
- Acknowledgements (2005) (0)
- Pharmacogenomics of Bioavailability and Elimination (2005) (0)
- Workshop at WorldPharma2010, Copenhagen, Denmark: “Implementation and Obstacles of Pharmacogenetics in Clinical Practice”, July 20, 2010 (2009) (0)
- Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia. (2023) (0)
- PIII‐30 (2006) (0)
- Molecular-epidemiological aspects of carcinogenesis: the role of xenobiotic metabolizing enzymes. (2002) (0)
- Age and gender differences in the association between MPO 463>A and lung cancer. Results from the genetic susceptibility to environmental carcinogens pooled analysis (2006) (0)
- Highlights from the latest articles in breast cancer pharmacogenomics. (2012) (0)
- [Clinical relevance of acetylator phenotyping in 196 urothelial tumor patients]. (1997) (0)
- Title : Association of Liver Injury From Specific Drugs , or Groups of Drugs , With Polymorphisms in HLA and Other Genes in a Genome-wide Association Study (2016) (0)
- Pioglitazone induces cell growth arrest and activates mitochondrial apoptosis in human uterine leiomyosarcoma cells by a peroxisome proliferator-activated receptor γ-independent mechanism (2016) (0)
- Transcriptional and epigenetic regulation of metabolizing enzymes and transporter proteins in the human intestine as caused by prototypical inducers of metabolism and transport (2018) (0)
- P0180 Effect of pioglitazone on proliferation and apoptosis in human uterine leiomyosarcoma cells (2015) (0)
- PP123—Target gene evaluation of two mirnas differently expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients (2013) (0)
- Reviewers 2011 (2012) (0)
- Linking pre-existing biorepositories for medical research: the PopGen 2.0 Network (2019) (0)
- "Obviously, genetic traits … are only one, and sometimes only a small piece in the puzzle of complex pharmacokinetic/pharmacodynamic modeling. " (2013) (0)
- Cancer Therapy : Preclinical Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 ( OCT 1 ) (2014) (0)
- Over-Regulation of Clinical Trials - A UK Problem? (2018) (0)
- Genetic and Epigenetic Mechanisms of Tki Resistance (2017) (0)
- Replication of Genetic Markers Associated with Clozapine-Induced Agranulocytosis. (2006) (0)
- Correspondence (reply): In Reply. (2013) (0)
- A UK problem (2008) (0)
- CYP1A1 alleles in women with focal nodular hyperplasia of the liver (FNH). (2004) (0)
- Polymorphic cytochrome P450 2D6 as the responsible enzyme of activation (2018) (0)
- Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells (2022) (0)
- The impact of Cytochrome P 450 2 D 6 and UDP-glucuronosyltransferase 1 A 1 genotypes on the toxicity of antidepressants and tranquilizers (2008) (0)
- Salute to Our Reviewers. (2016) (0)
- A NOVEL DEFECT CYP3A4 GENOTYPE IDENTIFIED IN A KIDNEY TRANSPLANT PATIENT WITH SEVERELY DIMINISHED TACROLIMUS CLEARANCE (2014) (0)
- [Significance of drug transporter for the internal medicine clinic]. (2003) (0)
- TRP Gene Polymorphism and Disease Risk (2015) (0)
- The role of myeloperoxidase and NADPH oxidase polymorphisms in clozapine-induced agranulocytosis (2004) (0)
- Slow N-acetylation phenotype in urothellal cancer patients (1995) (0)
- Breast cancer and vitamin D receptor polymorphism (1999) (0)
- COMPARISON OF MICRO-RNA EXPRESSION PROFILES IN PATIENTS BEFORE AND AFTER LONG TERM IMATINIB THERAPY AND BETWEEN RESPONDERS/NON-RESPONDERS (2011) (0)
- Conference Scene: Pharmacogenomic highlights of the DGPT Annual Congress. (2012) (0)
- Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme (2013) (0)
- IDENTIFICATION AND CHARACTERIZATION OF A NOVEL CYP3A4 VARIANT RESULTING FROM MISSENSE MUTATION FOUND IN KIDNEY TRANSPLANTED PATIENT WITH DEFECTS IN TACROLIMUS CLEARANCE (2014) (0)
- Abstract 5951: Role of Endothelin-1 in Upregulation of LOX-1 Expression in Hypertensive Rats (2008) (0)
- Ethnics: relevance of the genotype with special focus on drug metabolising enzymes and transporters (2004) (0)
- 5th Anniversary meeting of the European Research Network Pharmacogenetics/Pharmacogenomics. 8-9 December 2011, Utrecht, The Netherlands. (2012) (0)
- SELECTED ORAL COMMUNICATION SESSION, SESSION 03: REPRODUCTIVE AGEING AND AMH, Monday 4 July 2011 10:00 - 11:30 (2011) (0)
- Expressed in Human Heart The ATP-binding Cassette Transporter ABCG2 (BCRP), a Marker for Side Population Stem Cells, Is (2013) (0)
- Abstract 1097: MicroRNA expression in white blood cells of CML patients: Differential expression in responders and non-responders to imatinib (2012) (0)
- In Reply. (2018) (0)
- Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients (2011) (0)
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What Schools Are Affiliated With Ingolf Cascorbi?
Ingolf Cascorbi is affiliated with the following schools:
