Ingrid Fleming
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Molecular medicine researcher
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Philosophy
Ingrid Fleming's Degrees
- PhD Molecular Medicine Stanford University
- Masters Biochemistry University of California, San Francisco
- Bachelors Biology University of California, San Francisco
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(Suggest an Edit or Addition)Ingrid Fleming's Published Works
Published Works
- Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation (1999) (3606)
- Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. (2003) (941)
- EDHF: bringing the concepts together. (2002) (868)
- Cytochrome P450 2C is an EDHF synthase in coronary arteries (1999) (780)
- Phosphorylation of Thr495 Regulates Ca2+/Calmodulin-Dependent Endothelial Nitric Oxide Synthase Activity (2001) (693)
- Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active Cardiomyocytes (2003) (574)
- Endothelial dysfunction in atherosclerosis. (1996) (508)
- Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. (1990) (504)
- Endothelial aging. (2005) (470)
- Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. (1996) (461)
- Signal transduction of eNOS activation. (1999) (454)
- Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries (2001) (453)
- Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. (2001) (424)
- Cytochrome p450 and vascular homeostasis. (2001) (390)
- Molecular mechanisms underlying the activation of eNOS (2010) (388)
- Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium (2005) (348)
- Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis) (2000) (325)
- Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. (1997) (319)
- Phosphorylation and activation of the endothelial nitric oxide synthase by fluid shear stress. (2000) (309)
- Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells (2005) (302)
- Activation and signaling by the AMP-activated protein kinase in endothelial cells. (2009) (298)
- An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice. (2000) (296)
- Ca2+-independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress. (1998) (278)
- Pulsatile Stretch and Shear Stress: Physical Stimuli Determining the Production of Endothelium-Derived Relaxing Factors (1998) (269)
- Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells. (1996) (243)
- Epoxyeicosatrienoic acids and endothelium-dependent responses (2010) (239)
- The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo. (2013) (238)
- Phosphorylation of Threonine 497 in Endothelial Nitric-oxide Synthase Coordinates the Coupling of l-Arginine Metabolism to Efficient Nitric Oxide Production* (2003) (235)
- MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A. (2012) (232)
- Cytochrome P450 2C is an EDHF synthase in coronary arteries. (2000) (228)
- Valproic acid inhibits angiogenesis in vitro and in vivo. (2004) (227)
- Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets (2021) (212)
- Inhibitors of Histone Deacetylation Downregulate the Expression of Endothelial Nitric Oxide Synthase and Compromise Endothelial Cell Function in Vasorelaxation and Angiogenesis (2002) (212)
- NO: the primary EDRF. (1999) (204)
- A transferable, beta‐naphthoflavone‐inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells. (1996) (194)
- Inhibition of Diet-Induced Atherosclerosis and Endothelial Dysfunction in Apolipoprotein E/Angiotensin II Type 1A Receptor Double-Knockout Mice (2004) (187)
- Incubation with endotoxin activates the L-arginine pathway in vascular tissue. (1990) (187)
- Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen-activated protein kinases. (1995) (181)
- Mechanisms of nitric oxide release from the vascular endothelium (1993) (180)
- Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis (2005) (177)
- Cytochrome P450 2C9‐derived epoxyeicosatrienoic acids induce angiogenesis via cross‐talk with the epidermal growth factor receptor (2003) (177)
- Regulation and functional consequences of endothelial nitric oxide formation. (1995) (174)
- Soluble Epoxide Hydrolase Is a Main Effector of Angiotensin II–Induced Hypertension (2005) (171)
- S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β (2017) (171)
- Vasodilator dysfunction in aged spontaneously hypertensive rats: changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production. (1998) (170)
- Epoxyeicosatrienoic Acids Regulate Trp Channel–Dependent Ca2+ Signaling and Hyperpolarization in Endothelial Cells (2007) (169)
- Signaling by the Angiotensin-Converting Enzyme (2006) (168)
- The effect of inhibitors of the l‐arginine/nitric oxide pathway on endotoxin‐induced loss of vascular responsiveness in anaesthetized rats (1991) (159)
- 11,12-Epoxyeicosatrienoic Acid-induced Inhibition of FOXO Factors Promotes Endothelial Proliferation by Down-Regulating p27Kip1* (2003) (156)
- Calcium-dependent and calcium-independent activation of the endothelial NO synthase. (1997) (154)
- Cytochrome P450 epoxygenases as EDHF synthase(s). (2004) (154)
- Intracellular alkalinization induced by bradykinin sustains activation of the constitutive nitric oxide synthase in endothelial cells. (1994) (153)
- Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation. (2008) (153)
- Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces. (2003) (151)
- Dephosphorylation of endothelial nitric oxide synthase contributes to the anti‐angiogenic effects of endostatin (2002) (142)
- Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries. (2000) (140)
- Evidence that an l‐arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin (1991) (140)
- Nucleotide Excision DNA Repair Is Associated With Age-Related Vascular Dysfunction (2012) (137)
- Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase (2009) (134)
- Epoxyeicosatrienoic acids, cell signaling and angiogenesis. (2007) (133)
- From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling. (2006) (131)
- Analysis of Dichlorodihydrofluorescein and Dihydrocalcein as Probes for the Detection of Intracellular Reactive Oxygen Species (2004) (130)
- 20-HETE–Induced Contraction of Small Coronary Arteries Depends on the Activation of Rho-Kinase (2003) (129)
- The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase (2003) (129)
- Inhibition of Cytochrome P450 2C9 Improves Endothelium-Dependent, Nitric Oxide–Mediated Vasodilatation in Patients With Coronary Artery Disease (2004) (129)
- Cytochrome P450 2C9 plays an important role in the regulation of exercise‐induced skeletal muscle blood flow and oxygen uptake in humans (2003) (126)
- Endothelium-derived epoxyeicosatrienoic acids and vascular function. (2006) (126)
- Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction. (2012) (125)
- Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase. (1999) (123)
- Angiotensin-Converting Enzyme Is Involved in Outside-In Signaling in Endothelial Cells (2004) (123)
- The eNOS signalosome and its link to endothelial dysfunction (2016) (122)
- Cytochrome P450 2C9-induced Endothelial Cell Proliferation Involves Induction of Mitogen-activated Protein (MAP) Kinase Phosphatase-1, Inhibition of the c-Jun N-terminal Kinase, and Up-regulation of Cyclin D1* (2002) (121)
- Pulsatile stretch in coronary arteries elicits release of endothelium-derived hyperpolarizing factor: a modulator of arterial compliance. (1998) (121)
- P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction. (2015) (120)
- Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response (2008) (118)
- AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats. (2008) (116)
- Vascular Gene Transfer of Phosphomimetic Endothelial Nitric Oxide Synthase (S1177D) Using Ultrasound-Enhanced Destruction of Plasmid-Loaded Microbubbles Improves Vasoreactivity (2002) (116)
- The Pharmacology of the Cytochrome P450 Epoxygenase/Soluble Epoxide Hydrolase Axis in the Vasculature and Cardiovascular Disease (2014) (114)
- Cytochrome P450 Epoxygenase Gene Function in Hypoxic Pulmonary Vasoconstriction and Pulmonary Vascular Remodeling (2006) (113)
- Vascular cytochrome p450 enzymes: physiology and pathophysiology. (2008) (113)
- The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells (2001) (113)
- Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis. (2008) (113)
- Dynamic Modulation of Interendothelial Gap Junctional Communication by 11,12-Epoxyeicosatrienoic Acid (2002) (113)
- Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF‐mediated Ca2+ changes and dilation in isolated resistance arteries (2000) (109)
- MicroRNA-223 Antagonizes Angiogenesis by Targeting &bgr;1 Integrin and Preventing Growth Factor Signaling in Endothelial Cells (2013) (108)
- Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCα (2005) (106)
- Angiotensin-converting enzyme inhibitor ramiprilat interferes with the sequestration of the B2 kinin receptor within the plasma membrane of native endothelial cells. (1999) (106)
- Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells. (1991) (105)
- Platelet Sarcoplasmic Endoplasmic Reticulum Ca2+-ATPase and &mgr;-Calpain Activity Are Altered in Type 2 Diabetes Mellitus and Restored by Rosiglitazone (2008) (104)
- Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy (2017) (102)
- AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets (2003) (96)
- 12-Epoxyeicosatrienoic Acid-induced Inhibition of FOXO Factors Promotes Endothelial Proliferation by Down-Regulating p 27 Kip 1 * (2003) (95)
- The ADMA/DDAH pathway is a critical regulator of endothelial cell motility (2007) (95)
- Vascular endothelium and blood flow. (2006) (93)
- Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes. (2015) (92)
- Anaphylactic shock depends on endothelial Gq/G11 (2009) (92)
- Cyclic Stretch Enhances the Expression and Activity of Coronary Endothelium-Derived Hyperpolarizing Factor Synthase (2001) (91)
- Inhibition of Endothelial Nitric Oxide Synthase Activity by Proline-Rich Tyrosine Kinase 2 in Response to Fluid Shear Stress and Insulin (2008) (90)
- AMP-Activated Protein Kinase Regulates Endothelial Cell Angiotensin-Converting Enzyme Expression via p53 and the Post-Transcriptional Regulation of microRNA-143/145 (2013) (89)
- Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. (2019) (89)
- Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction (2020) (85)
- Aged Spontaneously Hypertensive Rats Exhibit a Selective Loss of EDHF-Mediated Relaxation in the Renal Artery (2003) (83)
- Gab1, SHP2, and Protein Kinase A Are Crucial for the Activation of the Endothelial NO Synthase by Fluid Shear Stress (2005) (82)
- Amlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser1177 and Thr495. (2003) (81)
- Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. (2003) (80)
- Signaling via the Angiotensin-Converting Enzyme Enhances the Expression of Cyclooxygenase-2 in Endothelial Cells (2005) (80)
- Insulin Induces the Release of Vasodilator Compounds From Platelets by a Nitric Oxide–G Kinase–VAMP-3–dependent Pathway (2004) (80)
- Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition. (2010) (80)
- Signal transduction in endothelium-dependent vasodilatation. (1993) (79)
- Bradykinin‐induced relaxation of coronary microarteries: S‐nitrosothiols as EDHF? (2004) (79)
- Cytochrome P4502C9-Derived Epoxyeicosatrienoic Acids Induce the Expression of Cyclooxygenase-2 in Endothelial Cells (2004) (77)
- Interdependence of Calcium Signaling and Protein Tyrosine Phosphorylation in Human Endothelial Cells (*) (1996) (77)
- Nitric oxide and endotoxemia (1993) (75)
- Cystathionine &ggr; Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis (2019) (75)
- Nitric Oxide-Induced Activation of the AMP-Activated Protein Kinase α2 Subunit Attenuates IκB Kinase Activity and Inflammatory Responses in Endothelial Cells (2011) (73)
- Monoamine Oxidases Are Mediators of Endothelial Dysfunction in the Mouse Aorta (2013) (72)
- Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols (2012) (72)
- Müller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid (2014) (72)
- Fluid Shear Stress and NO Decrease the Activity of the Hydroxy-Methylglutaryl Coenzyme A Reductase in Endothelial Cells via the AMP-Activated Protein Kinase and FoxO1 (2007) (70)
- Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2 (2011) (69)
- The tissue renin–angiotensin system and intracellular signalling (2006) (66)
- Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages* (2015) (66)
- New fACEs to the renin-angiotensin system. (2005) (65)
- Lipocalin 2 from macrophages stimulated by tumor cell–derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis (2016) (65)
- Molecular Responses of Endothelial Tissue to Kinins (1996) (64)
- Insulin, Insulin Resistance, and Platelet Signaling in Diabetes (2009) (63)
- Inhibition of the production of endothelium‐derived hyperpolarizing factor by cannabinoid receptor agonists (1999) (63)
- DiscrEET regulators of homeostasis: epoxyeicosatrienoic acids, cytochrome P450 epoxygenases and vascular inflammation. (2007) (63)
- Interactions between thromboxane A₂, thromboxane/prostaglandin (TP) receptors, and endothelium-derived hyperpolarization. (2014) (61)
- CK2 Phosphorylates the Angiotensin-Converting Enzyme and Regulates Its Retention in the Endothelial Cell Plasma Membrane (2002) (61)
- Shear stress-induced activation of the AMP-activated protein kinase regulates FoxO1a and angiopoietin-2 in endothelial cells. (2008) (61)
- Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes. (2012) (60)
- Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. (2019) (60)
- Mechanisms of Increased Vascular Superoxide Production in an Experimental Model of Idiopathic Dilated Cardiomyopathy (2005) (59)
- Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats (2009) (57)
- Characterization of the endothelium-derived hyperpolarizing factor (EDHF) response in the human interlobar artery. (2003) (56)
- Control of nitric oxide and prostacyclin synthesis in endothelial cells. (1994) (55)
- EGFL7 ligates αvβ3 integrin to enhance vessel formation. (2013) (55)
- Chronic selective hypertriglyceridemia impairs endothelium-dependent vasodilatation in rats. (1999) (55)
- Soluble Epoxide Hydrolase Deficiency Attenuates Neointima Formation in the Femoral Cuff Model of Hyperlipidemic Mice (2010) (55)
- Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation (2011) (51)
- Leptin Potentiates Endothelium-Dependent Relaxation by Inducing Endothelial Expression of Neuronal NO Synthase (2012) (51)
- Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis. (2015) (51)
- The Biological Actions of 11,12-Epoxyeicosatrienoic Acid in Endothelial Cells Are Specific to the R/S-Enantiomer and Require the Gs Protein (2014) (51)
- NADPH Oxidase Accounts for Enhanced Superoxide Production and Impaired Endothelium-Dependent Smooth Muscle Relaxation in BK&bgr;1−/− Mice (2006) (51)
- miR-223-IGF-IR signalling in hypoxia- and load-induced right-ventricular failure: a novel therapeutic approach. (2016) (51)
- Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression. (2003) (50)
- Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCalpha. (2005) (50)
- Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS. (2019) (49)
- The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation. (2005) (48)
- Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats. (1993) (48)
- Cytochrome P450-Derived Epoxyeicosatrienoic Acids and Pulmonary Hypertension: Central Role of Transient Receptor Potential C6 Channels (2011) (48)
- Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype (2011) (48)
- Endothelial nitric oxide synthase (eNOS) in platelets: how is it regulated and what is it doing there? (2005) (47)
- Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells. (2008) (46)
- Cytochrome P450 Enzymes in Vascular Homeostasis (2001) (46)
- From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” (2016) (46)
- Cytochrome P450 2C9 is involved in flow‐dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure (2007) (46)
- A selective and sensitive method for quantification of endogenous polysulfide production in biological samples (2018) (46)
- Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice (2020) (45)
- Prevention of endothelial dysfunction in heart failure by vitamin E: attenuation of vascular superoxide anion formation and increase in soluble guanylyl cyclase expression. (2001) (45)
- AMPK α2 subunit is involved in platelet signaling, clot retraction, and thrombus stability. (2010) (44)
- Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation. (2014) (44)
- The factor in EDHF: Cytochrome P450 derived lipid mediators and vascular signaling. (2016) (44)
- Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques (2012) (44)
- Angiotensin-Converting Enzyme (ACE) Dimerization Is the Initial Step in the ACE Inhibitor-Induced ACE Signaling Cascade in Endothelial Cells (2006) (43)
- Hyperthyroidism enhances endothelium-dependent relaxation in the rat renal artery. (2003) (43)
- Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole. (2003) (43)
- The endothelial organ (1993) (42)
- Endothelium-derived bradykinin: implications for angiotensin-converting enzyme-inhibitor therapy. (1993) (42)
- Transforming Growth Factor-&bgr;–Activated Kinase 1 Regulates Angiogenesis via AMP-Activated Protein Kinase-&agr;1 and Redox Balance in Endothelial Cells (2013) (42)
- Endothelium‐Derived Kinins Account for the Immediate Response of Endothelial Cells to Bacterial Lipopoly saccharide (1992) (41)
- The extracellular regulated kinases (ERK) 1/2 mediate cannabinoid‐induced inhibition of gap junctional communication in endothelial cells (2002) (41)
- 5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia. (2014) (41)
- Deleted in Malignant Brain Tumors 1 is Present in the Vascular Extracellular Matrix and Promotes Angiogenesis (2012) (41)
- HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma. (2015) (39)
- The cytochrome P450 pathway in angiogenesis and endothelial cell biology (2011) (39)
- Impaired interaction of platelets with endothelial progenitor cells in patients with cardiovascular risk factors (2008) (39)
- Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. (1997) (38)
- Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas. (1993) (37)
- Unchanged NADPH Oxidase Activity in Nox1-Nox2-Nox4 Triple Knockout Mice: What Do NADPH-Stimulated Chemiluminescence Assays Really Detect? (2016) (37)
- The S1P2 receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes (2009) (37)
- Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy (2013) (36)
- Cytochrome P450 2C9-Induced Angiogenesis Is Dependent on EphB4 (2008) (36)
- Activation of the l arginine nitric oxide pathway is involved in vascular hyporeactivity induced by endotoxin (1991) (36)
- An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium. (1990) (36)
- EDHF: a cytochrome P450 metabolite in coronary arteries. (2000) (36)
- Cytochrome P450 2C expression and EDHF-mediated relaxation in porcine coronary arteries is increased by cortisol. (2002) (36)
- Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. (2020) (35)
- Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells (2018) (35)
- P 2 Y 2 and G q / G 11 control blood pressure by mediating endothelial mechanotransduction (2019) (35)
- The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice (2017) (34)
- Calcium signalling and autacoid production in endothelial cells are modulated by changes in tyrosine kinase and phosphatase activity. (1996) (34)
- Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside (2015) (34)
- Inhibition of the Soluble Epoxide Hydrolase by Tyrosine Nitration* (2009) (34)
- The F‐BAR protein NOSTRIN participates in FGF signal transduction and vascular development (2012) (33)
- The Na‐K‐ATPase is a target for an EDHF displaying characteristics similar to potassium ions in the porcine renal interlobar artery (2002) (33)
- Pro-inflammatory obesity in aged cannabinoid-2 receptor-deficient mice (2016) (33)
- Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH‐dependent lucigenin chemiluminescence in membrane assays (2017) (33)
- AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis (2017) (33)
- Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function. (2020) (32)
- Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug (2018) (32)
- Angiotensin-Converting Enzyme (ACE) Inhibitors Modulate Cellular Retinol-Binding Protein 1 and Adiponectin Expression in Adipocytes via the ACE-Dependent Signaling Cascade (2009) (32)
- Ca -Independent Activation of the Endothelial Nitric Oxide Synthase in Response to Tyrosine Phosphatase Inhibitors and Fluid Shear Stress (1998) (31)
- Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition (2019) (31)
- Calpain 1 cleaves and inactivates prostacyclin synthase in mesenteric arteries from diabetic mice (2016) (31)
- Paracrine functions of the coronary vascular endothelium (1996) (31)
- CYP4A11 polymorphism correlates with coronary endothelial dysfunction in patients with coronary artery disease--the ENCORE Trials. (2009) (31)
- Cytochrome P450-derived epoxyeicosatrienoic acids accelerate wound epithelialization and neovascularization in the hairless mouse ear wound model (2011) (31)
- β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function (2016) (31)
- 11,12-EET Stimulates the Association of BK Channel α and β1 Subunits in Mitochondria to Induce Pulmonary Vasoconstriction (2012) (31)
- Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients: Rescue by &agr;-Ketoglutarate and TET-TDG Functional Reactivation (2018) (30)
- cAMP Phosphodiesterase Inhibitors Increases Nitric Oxide Production by Modulating Dimethylarginine Dimethylaminohydrolases (2011) (29)
- Signaling via the Angiotensin-Converting Enzyme Results in the Phosphorylation of the Nonmuscle Myosin Heavy Chain IIA (2006) (29)
- Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5 (2015) (29)
- Adenoviral-mediated overexpression of DDAH improves vascular tone regulation (2010) (29)
- Cytochrome P450-dependent eicosanoid production and crosstalk (2011) (28)
- Increased cerebrospinal fluid calpain activity and microparticle levels in Alzheimer's disease (2015) (28)
- Ca2+-sensing Receptor Cleavage by Calpain Partially Accounts for Altered Vascular Reactivity in Mice Fed a High-fat Diet (2013) (28)
- Control and consequences of endothelial nitric oxide formation. (1995) (28)
- VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia (2018) (27)
- Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men[S] (2016) (27)
- Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation (2019) (27)
- Nitric oxide and endothelium-derived hyperpolarizing factor: formation and interactions. (1997) (27)
- Soluble epoxide hydrolase disruption as therapeutic target for wound healing. (2013) (26)
- Methylglyoxal Induces Platelet Hyperaggregation and Reduces Thrombus Stability by Activating PKC and Inhibiting PI3K/Akt Pathway (2013) (26)
- Nitric oxide formation in the vascular wall: regulation and functional implications. (1995) (26)
- Effect of endotoxin on circulating cyclic GMP in the rat. (1992) (25)
- Bobbing along on the crest of a wave: NO ascends hamster cheek pouch arterioles. (2003) (25)
- Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase (2018) (25)
- The effects of COX-2 selective and non-selective NSAIDs on the initiation and progression of atherosclerosis in ApoE−/− mice (2007) (24)
- Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection (2017) (23)
- Metformin reduces hyper-reactivity of platelets from patients with polycystic ovary syndrome by improving mitochondrial integrity (2015) (23)
- Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1. (2009) (23)
- Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2 (2017) (22)
- aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability (2018) (22)
- Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B (2017) (22)
- Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants (2021) (22)
- Regulation of NO Synthesis in Endothelial Cells (2008) (22)
- Angiopoietin‐2 mediates thrombin‐induced monocyte adhesion and endothelial permeability (2016) (21)
- Nitric oxide- and EDHF-mediated arteriolar tone in uremia is unaffected by selective inhibition of vascular cytochrome P450 2C9. (2005) (20)
- Nitric oxide, nitric oxide synthase, and hypertensive vascular disease (1999) (20)
- Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity. (2007) (20)
- Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension. (2005) (20)
- The number of cardiac myocytes in the hypertrophic and hypotrophic left ventricle of the obese and calorie‐restricted mouse heart (2014) (19)
- AKAP12 deficiency impairs VEGF‐induced endothelial cell migration and sprouting (2019) (19)
- Inhibition of Cytochrome P 450 2 C 9 Improves Endothelium-Dependent , Nitric Oxide – Mediated Vasodilatation in Patients With Coronary Artery Disease (2004) (19)
- Increased Cytochrome P4502E1 Expression and Altered Hydroxyeicosatetraenoic Acid Formation Mediate Diabetic Vascular Dysfunction (2010) (19)
- Platelet function and signaling in diabetes mellitus. (2012) (19)
- Stereological characterization of left ventricular cardiomyocytes, capillaries, and innervation in the nondiabetic, obese mouse. (2012) (19)
- Endothelium-derived hyperpolarizing factor, but not nitric oxide, is reversibly inhibited by brefeldin A. (1997) (18)
- VE-PTP inhibition elicits eNOS phosphorylation to blunt endothelial dysfunction and hypertension in diabetes. (2020) (18)
- Gab 1 , SHP 2 , and Protein Kinase A Are Crucial for the Activation of the Endothelial NO Synthase by Fluid Shear Stress (2005) (18)
- Platelet-Enriched MicroRNAs and Cardiovascular Homeostasis. (2017) (18)
- Role of cytochrome P450-derived, polyunsaturated fatty acid mediators in diabetes and the metabolic syndrome. (2019) (18)
- Tyrosine Phosphatase Inhibitors and Fluid Shear Stress-Independent Activation of the Endothelial Nitric Oxide Synthase in Response to 2 + Ca (1998) (17)
- Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation (2018) (17)
- All cut up! The consequences of calpain activation on platelet function. (2012) (16)
- Complementary Screening Techniques Yielded Fragments that Inhibit the Phosphatase Activity of Soluble Epoxide Hydrolase (2011) (16)
- Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction. (2019) (16)
- Myoendothelial gap junctions: the gap is there, but does EDHF go through it? (2000) (16)
- Molecular pharmacological profile of a novel thiazolinone‐based direct and selective 5‐lipoxygenase inhibitor (2012) (15)
- Mitochondrial fragmentation in human macrophages attenuates palmitate-induced inflammatory responses. (2018) (15)
- Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy (2018) (15)
- Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins (2019) (15)
- The soluble epoxide hydrolase determines cholesterol homeostasis by regulating AMPK and SREBP activity. (2016) (15)
- Angiogenesis and vascular stability in eicosanoids and cancer (2018) (15)
- Impaired vascular reactivity in the rat following endotoxin treatment can be endothelium independent, yet involves the L-arginine pathway (1990) (14)
- The F-BAR Protein NOSTRIN Dictates the Localization of the Muscarinic M3 Receptor and Regulates Cardiovascular Function. (2015) (14)
- Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity. (2019) (14)
- HIF‐2α attenuates lymphangiogenesis by up‐regulating IGFBP1 in hepatocellular carcinoma (2015) (14)
- Phosphorylation of vasodilator-stimulated phosphoprotein contributes to myocardial ischemic preconditioning (2018) (14)
- Role of the angiotensin-converting enzyme in the G-CSF-induced mobilization of progenitor cells (2018) (14)
- Epigenetic control of the angiotensin-converting enzyme in endothelial cells during inflammation (2019) (13)
- G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators (2021) (13)
- Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells (2018) (13)
- The role of calpain in diabetes-associated platelet hyperactivation. (2010) (13)
- Vascular cytochrome P450 in the regulation of renal function and vascular tone: EDHF, superoxide anions and blood pressure. (2001) (13)
- EVL regulates VEGF receptor‐2 internalization and signaling in developmental angiogenesis (2021) (12)
- Thrombin receptor expression is increased by angiotensin II in cultured and native vascular smooth muscle cells. (1998) (12)
- Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis. (2017) (12)
- Whatever happened to the epoxyeicosatrienoic Acid-like endothelium-derived hyperpolarizing factor? The identification of novel classes of lipid mediators and their role in vascular homeostasis. (2015) (12)
- Anomalous Kv7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2S and persulfidation in skeletal muscle (2020) (12)
- The Pharmacology of the Cytochrome P 450 Epoxygenase / Soluble Epoxide Hydrolase Axis in the Vasculature and Cardiovascular Disease (2014) (12)
- A Modified Aortic Ring Assay to Assess Angiogenic Potential In Vitro. (2016) (12)
- One miR level of control: microRNA-155 directly regulates endothelial nitric oxide synthase mRNA and protein levels. (2012) (11)
- Brain in the brawn: the neuronal nitric oxide synthase as a regulator of myogenic tone. (2003) (11)
- Activation of adenosine-monophosphate-activated protein kinase abolishes desflurane-induced preconditioning against myocardial infarction in vivo. (2011) (10)
- Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux. (2017) (10)
- Induced Hypertension − Soluble Epoxide Hydrolase Is a Main Effector of Angiotensin II (2005) (10)
- Oxidative post translational modifications: a focus on cysteine S-sulfhydration and the regulation of endothelial fitness. (2021) (10)
- Platelet communication with the vascular wall: role of platelet-derived microparticles and non-coding RNAs. (2018) (9)
- Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes (2020) (9)
- The role of eNOS on the compensatory regulation of vascular tonus by H2S in mouse carotid arteries. (2017) (9)
- Regulation of calpain 2 expression by miR-223 and miR-145. (2019) (9)
- Cirrhosis serum induces a nitric oxide-associated vascular hyporeactivity of aortic segments from healthy rats in vitro (2001) (9)
- Biology of Nitric Oxide Synthases (2011) (9)
- Association between arginase-containing platelet-derived microparticles and altered plasma arginine metabolism in polycystic ovary syndrome. (2019) (9)
- Can erythrocytes release biologically active NO? (2016) (9)
- ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function (2019) (8)
- Secreted modular calcium binding protein 1 binds/activates thrombin to account for platelet hyper-reactivity in diabetes. (2021) (8)
- New Lipid Mediators in Retinal Angiogenesis and Retinopathy (2019) (8)
- Mechanisms of Vascular Impairment During Endotoxaemia with special Reference to the Role of the L-arginine Pathway. (1991) (8)
- Fluid Shear Stress and NO Decrease the Activity of the Hydroxy-Methylglutaryl Coenzyme A Reductase in Endothelial Cells via the AMP-Activated Protein Kinase and FoxO 1 (2007) (8)
- Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis (2019) (8)
- Activation of NOS by Ca2+-Dependent and Ca2+-Independent Mechanisms (2000) (7)
- Redox Regulation of Calpains: Consequences on Vascular Function. (2019) (7)
- Pathophysiology of Chronic Venous Insufficiency (1996) (7)
- A novel APJ signaling cascade that regulates cardiovascular development. (2013) (7)
- Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion (2016) (6)
- Endothelium-Derived Hyperpolarizing Factor and Its Interaction with NO (2000) (6)
- Abstract 12476: Increased Cytochrome P4502E1 Expression and Altered Hydroxyeicosatetraenoic Acid Formation Mediate Diabetic Vascular Dysfunction: Rescue by Guanylyl-Cyclase Activation (2010) (6)
- The histone demethylase Jarid1b mediates angiotensin II‐induced endothelial dysfunction by controlling the 3′UTR of soluble epoxide hydrolase (2019) (6)
- Endothelial function is impaired in aortae from lipopolysaccharide (LPS)-treated rats (1990) (6)
- Realizing its potential: the intermediate conductance Ca2+-activated K+ channel (KCa3.1) and the regulation of blood pressure. (2006) (6)
- Kinin-mediated activation of endothelial no formation: possible role during myocardial ischemia. (1995) (6)
- , John and Pulmonary Vascular Remodeling Cytochrome P 450 Epoxygenase Gene Function in Hypoxic Pulmonary Vasoconstriction (2006) (5)
- [Communication between endothelial and smooth muscle cells]. (2003) (5)
- Double tribble: two TRIB3 variants, insulin, Akt, and eNOS. (2008) (5)
- The Role of the L-Arginine Nitric Oxide Pathway in Sepsis and Endotoxaemia with Special Reference to Vascular Impairment (1993) (5)
- Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer (2020) (5)
- To move or not to move? Cytochrome P450 products and cell migration. (2002) (5)
- Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease (2020) (5)
- Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats (2020) (5)
- MicroRNA-124 Alleviates Retinal Vasoregression via Regulating Microglial Polarization (2021) (5)
- A critical look at cardiovascular translational research. (1999) (4)
- Nitric Oxide and Regulation of Vascular Tone (2000) (4)
- Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARγ Modulator. (2021) (4)
- IL27Rα Deficiency Alters Endothelial Cell Function and Subverts Tumor Angiogenesis in Mammary Carcinoma (2019) (4)
- P186. Tyrosine phosphorylation of the nitric oxide synthase by PYK2 attenuates enzyme activity (2006) (4)
- Cytochrome P450-derived fatty acid epoxides and diols in angiogenesis and stem cell biology. (2021) (4)
- Mechanisms, therapeutic implications, and methodological challenges of gut microbiota and cardiovascular diseases: a position paper by the ESC Working Group on Coronary Pathophysiology and Microcirculation. (2022) (4)
- The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast Cancer (2021) (4)
- A critical look at cardiovascular translational research. (1999) (4)
- Cytochrome P 450 2 C 9-Induced Angiogenesis Is Dependent on EphB 4 (2008) (4)
- Identification of a cis-element regulating transcriptional activity in response to fluid shear stress in bovine aortic endothelial cells. (2003) (4)
- OUTSIDE-IN SIGNALLING BY THE ANGIOTENSIN CONVERTING ENZYME IN ENDOTHELIAL CELLS: A NOVEL SIGNALLING PATHWAY (2004) (4)
- Enhancement of cyclic GMP synthesis contributes to depression of vascular reactivity by endotoxin (1990) (4)
- Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome to Maintain Tumor-Promoting Inflammation. (2022) (3)
- Nitric oxide – and EDHF-mediated arteriolar tone in uremia is unaffected by selective inhibition of vascular cytochrome P 450 2 C 9 (2010) (3)
- Physiology of the endothelium: from a molecular point of view (2009) (3)
- The ADMA/DDAH pathway is a critical regulator of endothelial cell motility (2007) (3)
- Segregation and integration: roles played by caveolae and caveolins in the cardiovascular system. (2006) (3)
- Annexing AXL: Endothelial Cell Infection by the Zika Virus. (2016) (3)
- Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice (2022) (3)
- Vascular Effects of NO (1997) (3)
- Growth Factor Signaling in Endothelial Cells 1 Integrin and Preventing β MicroRNA-223 Antagonizes Angiogenesis by Targeting (2013) (2)
- Epoxyeicosatrienoic acids: regulators of vascular homeostasis (2006) (2)
- Prostaglandin H Synthase and Vascular Function (2001) (2)
- Energy and motion: AMP‐activated protein kinase α1 and its role in platelet activation (2014) (2)
- Regulation of Platelet Function by Flow-Induced Release of Endothelial Autacoids (1995) (2)
- Chapter 23 – NO Signaling Defects in Hypertension (2017) (2)
- Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function. (2022) (2)
- Correction: 11,12-EET Stimulates the Association of BK Channel α and β1 Subunits in Mitochondria to Induce Pulmonary Vasoconstriction (2012) (2)
- Nitric Oxide Inhibits Glomerular TGF- Signaling via SMOC-1 (2009) (2)
- MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity (2022) (2)
- Effect of Thrombin on the Metabolism and Function of Murine Macrophages (2022) (2)
- Development and Characterization of a Fluorescent Ligand for Leukotriene B4 Receptor 2 in Cells and Tissues. (2022) (2)
- Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery (2021) (2)
- Disruption of prostaglandin E2 signaling in cancer-associated fibroblasts limits mammary carcinoma growth but promotes metastasis. (2022) (2)
- AGMO Inhibitor Reduces 3T3-L1 Adipogenesis (2021) (2)
- Cyclin Y Is Expressed in Platelets and Modulates Integrin Outside-in Signaling (2020) (2)
- CYTOCHROME P450 2C‐DERIVED EPOXYEICOSATRIENOIC ACIDS REGULATE CA2+ SIGNALLING AND HYPERPOLARIZATION IN ENDOTHELIAL CELLS (2006) (2)
- Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD (2022) (2)
- Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux (2017) (2)
- Featured Articles Increased cerebrospinal fluid calpain activity and microparticle levels in Alzheimer's disease (2014) (1)
- Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy (2013) (1)
- EGFL 7 ligates a v b 3 integrin to enhance vessel formation (2013) (1)
- Human platelets are a source of collagen I. (2020) (1)
- Abstract 702: Angiotensin Converting Enzyme (ACE) Inhibitors Modulate Gene Expression in Human Endothelial Cells and Adipocytes via the ACE-Dependent Signaling (2006) (1)
- Who is afraid of being a reviewer? An A-Z of tips and tricks for peer review. (2021) (1)
- Incubation with endotoxin (ETX) induces vascular hyporeactivity which is reversed by NGmonomethyl-L-arginine (L-NMMA) (1990) (1)
- Coronary revascularization is regulated by epicardial and endocardial cues and forms a scaffold for cardiomyocyte repopulation (2020) (1)
- Epoxyeicosatrienoic acids act as second messengers in VEGF-induced angiogenesis (2006) (1)
- Translating GWAS Into the Flow-Regulated Modulation of Lipid Mediator Signaling. (2015) (1)
- the Endothelial Cell Plasma Membrane CK 2 Phosphorylates the Angiotensin-Converting Enzyme and Regulates Its Retention in (2002) (1)
- A spoonful of sugar helps the medicine go down… but platelet eNOS activity go up! (2005) (1)
- Apoptotic Cells induce Proliferation of Peritoneal Macrophages (2021) (1)
- EDHE: update on an alternative vasodilator with potential renal significance. (1998) (1)
- The AMP-activated protein kinase (AMPK) decreases endothelial angiotensin converting enzyme (ACE) expression by phosphorylation of p53 and post-transscriptional upregulation of microRNA (miR)-143/145 (2013) (1)
- A mlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser and Thr (2003) (1)
- Conference Calendar (2005) (0)
- The Intermediate Conductance Ca -Activated K Channel (KCa3.1) and the Regulation of Blood Pressure (2006) (0)
- aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability (2018) (0)
- diabetes Calpain inhibition stabilizes the platelet proteome and reactivity in (2012) (0)
- Cytochrome P450 epoxygenase inhibition attenuates hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling (2005) (0)
- Abstract 5559: Role of AMP-activated Protein Kinase in Ischemia-Reperfusion-Induced Barrier Failure in Endothelial Monolayers (2008) (0)
- Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts (2023) (0)
- Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells (2018) (0)
- Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice (2020) (0)
- A novel role for cystathionine γ lyase in the control of p53: impact on endothelial senescence and metabolic reprograming (2022) (0)
- The inhibition of soluble epoxide hydrolase protects from retinal vasoregression (2015) (0)
- The eNOS signalosome and its link to endothelial dysfunction (2016) (0)
- Into Functionally Active Cardiomyocytes Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor (2003) (0)
- 21Phosphorylation of eNOS on Tyrosine 656 contributes to endothelial dysfunction in vivo (2018) (0)
- Cytochrome P450 reductase contributes to NADPH-dependent signal in membrane assays used for measuring Nox activity (2018) (0)
- Molecular Mechanisms of Angiogenesis: A Brief Scientific History (2006) (0)
- 12,13‐dihydroxyoctadecenoic acid regulates hematopoietic stem cell and progenitor cell function in zebrafish and mouse (2012) (0)
- basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting frontiers in cardiovascular 69-81. (2016) (0)
- The AMP-activated protein kinase modifies gene expression in endothelial cells by interfering with protein lysine acetylation (2012) (0)
- Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth (2022) (0)
- Mechanisms of Shear Stress-Dependent Endothelial Nitric Oxide Release: Cardiovascular Implications (1995) (0)
- Angiotensin converting enzyme (ACE) inhibitors elicit the dimerization of ACE: an essential step for ACE‐dependent signaling in endothelial cells (2006) (0)
- P358The role of AMP-activated protein kinase in angiogenesis (2018) (0)
- Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation. (2023) (0)
- Cytochrome P450 2C9 induces the expression of EphB4 in endothelial cells (2006) (0)
- Correction: Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion (2017) (0)
- Regulation of the soluble epoxide hydrolase by peroxynitrite (2008) (0)
- Response to Pagano et al. (2015) (0)
- Vasoconstriction and Pulmonary Vascular Remodeling Cytochrome P450 Epoxygenase Gene Function in Hypoxic Pulmonary (2006) (0)
- Cytochrome P450 is the Source of NADPH-Dependent Signal in Cell-Free Assays for Nox Activity (2016) (0)
- Abstract 625: Cytochrome P450 2C9-induced Angiogenesis Involves the Expression of EphB4 and ephrinB2 in Endothelial Cells (2006) (0)
- 11,12-EET Regulates PPAR-γ Expression to Modulate TGF-β-Mediated Macrophage Polarization (2023) (0)
- miRNA-223 regulates platelet function by targeting + (2013) (0)
- Inhibition of the soluble epoxide hydrolase (sEH) alters vascular remodeling (2008) (0)
- Abstract 2616: Role of the Soluble Epoxide Hydrolase in Hypoxic Pulmonary Vasoconstriction and Pulmonary Vascular Remodeling (2008) (0)
- O.9.1Human secreted modular Ca2+-binding protein 1 is involved in inflammatory matrix remodelling through interference in cytokine signalling (2012) (0)
- Abstract 1332: Fluid Shear Stress-Dependent Activation of the AMP-Activated Protein Kinase Attenuates Ras-Dependent Signaling by Inhibiting the Activity and Expression of the Hydroxy-Methylglutaryl Coenzyme A Reductase in Endothelial Cells (2006) (0)
- Cystathionine gamma lyase expression/activity delays endothelial senescence (2022) (0)
- Abstract 1305: Epoxyeicosatrienoic Acids Are Part Of The Vascular Endothelial Growth Factor-activated Signaling Cascade In Endothelial Cells Resulting In The Formation Of Fully Functional Vessels (2007) (0)
- [YIA] Myeloid cell derived Interleukin-6 causes vascular dysfunction, inflammation and endothelin-1 expression in mice (2022) (0)
- Transfection of primary endothelial cells with siRNA v1 (2019) (0)
- Abstract 1307: TRPV4 Plays a Crucial Role in NO- and Prostacyclin-independent, Flow-induced Vasodilation (2006) (0)
- Abstract 303: The Shear Stress-Induced Activation of the AMP-Activated Protein Kinase Regulates FoxO1a and Angiopoietin-2 Expression in Endothelial Cells (2006) (0)
- Platelet Sarcoplasmic Endoplasmic Reticulum Ca 2 (cid:1) -ATPase and (cid:2) -Calpain Activity Are Altered in Type 2 Diabetes Mellitus and Restored by Rosiglitazone Molecular Cardiology (2007) (0)
- Lipid signaling mediators mEET TRP channels: highlighted presentations from the March 2010 Winter Eicosanoid Conference. (2011) (0)
- Cytochrome P450 epoxygenase inhibition attenuates hypoxia-induced pulmonary vasoconstriction and vascular remodelling in mice (2005) (0)
- Editorial on "Full-length dhh and N-terminal shh act as competitive antagonists to regulateangiogenesis and vascular permeability". (2021) (0)
- O75. Angiotensin II inactivates eNOS through tyrosine phosphorylation (2008) (0)
- Abstract 3660: Signal-Responsive Repression of Notch1 Signaling by the Sirt1 Deacetylase Regulates Sprouting Angiogenesis (2008) (0)
- P564L-cystathionine metabolism by cystathionine gamma lyase generates H2S to preserve endothelial cell function and decelerate atherosclerosis development in humans (2018) (0)
- Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men patient-oriented and epidemiological research (2020) (0)
- Hypoxic pulmonary vasoconstriction requires endothelial signal conduction via connexin 40 (2012) (0)
- The soluble epoxide hydrolase attenuates pathological vascularization by preventing astrocyte loss in a retinopathy of prematurity model in mice (2018) (0)
- Prostaglandins and Other Lipid Mediators (POLM), Special Issue of the 6th European Workshop on Lipid Mediators (2020) (0)
- Redox Control of Renal Metabolism and Transport Function by the NADPH Oxidase Nox4 (2017) (0)
- 865-1 Endothelium-derived hyperpolarizing factor is involved in flow-dependent dilation of peripheral conduit arteries in healthy volunteers (2004) (0)
- P377Inhibition of the soluble epoxide hydrolase attenuates diabetic retinopathy (2018) (0)
- sEH‐deficiency attenuates neointima formation in the femoral artery cuff model of hyperlipidemic mice (2009) (0)
- Abstract 147: The AMP-Activated Protein Kinase (AMPK) -Dependent Regulation of Endothelial Cell Angiotensin-Converting Enzyme (ACE) Expression Involves p53 and MicroRNA-143/145 (2012) (0)
- Dysregulation of Angiogenesis in the mdx Model of Duchenne Muscular Dystrophy (2021) (0)
- Abstract 1665: Angiotensin II Inactivates eNOS Through Tyrosine Phosphorylation (2008) (0)
- management of stem cell-like cells in acute myeloid leukemia 5-lipoxygenase is a candidate target for therapeutic (2014) (0)
- Abstract 453: The S1p2 Receptor Is Expressed In Human Platelets,is Linked To The Rhoa-rho Kinase Pathway And Is Degraded By {micro}-calpain In Type 2 Diabetes (2007) (0)
- Can erythrocytes release biologically active NO? (2016) (0)
- The role of calpain in regulating platelet physiology and crosstalk with the vasculature (2012) (0)
- Angiotensin converting enzyme (ACE) inhibitors induce an ACE-dependent signalling in endothelial cells via the initial dimerisation of ACE (2006) (0)
- Molecular Biology/Cell Biology/Human Genetics/Anatomy/ Embryology (2008) (0)
- Activation of AMP‐activated protein kinase protects endothelial barrier against reperfusion‐induced failure (2009) (0)
- Phosphorylation of NO synthase. Impact on endothelial function (2000) (0)
- Tumor and Stem Cell Biology 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell–like Cells in Acute Myeloid Leukemia (2014) (0)
- Abstract 662: The Acute Hypoxic Pulmonary Vasoconstrictor Response And Pulmonary Artery Pressure Are Modified By The Soluble Epoxide Hydrolase And Epoxyeicosatrienoic Acids. (2007) (0)
- Identification of septin-5 as a novel calpain substrate and its role in platelet secretion (2012) (0)
- PHARMREV007781 1106..1140 (2014) (0)
- Author Correction: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice (2022) (0)
- Cytochrome P450-Derived Lipid Mediators and Vascular Responses (2015) (0)
- Isolation of endothelial cells from umbillical vessels v1 (2019) (0)
- Cytochrome Inhibition of P450 epoxygenase attenuates hypoxia-induced pulmonary vasoconstriction and vascular remodeling in mice (2006) (0)
- Abstract P258: Effect of MicroRNA-223 on Hypoxic Pulmonary Hypertension (2011) (0)
- Coenzyme A Reductase in Endothelial Cells via the AMP-Activated Protein Kinase and Fluid Shear Stress and NO Decrease the Activity of the Hydroxy-Methylglutaryl (2007) (0)
- Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy (2018) (0)
- Ischemic heart disease : the next target for the angiotensin-converting enzyme inhibitors (2003) (0)
- The shear stress-induced activation of the AMP-activated protein kinase (AMPK) regulates FoxO1a activity and angiopoietin-2 expression in endothelial cells (2006) (0)
- Cytochrone P450 epoxygenase inhibition attenuates hypoxia-induced pulmonary vasoconstriction and vascular remodeling in mice (2005) (0)
- Abstract 19033: Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation (2016) (0)
- Angiotensin converting enzyme ( ACE ) inhibitors modulate CRBP 1 and adiponectin expression in adipocytes via the ACE-dependent signaling cascade (2008) (0)
- Müller Cells Regulate Notch Signaling And Retinal Angiogenesis Via The Soluble Epoxide Hydrolase‐Dependent Generation Of 19,20‐Dihydroxydocosapentaenoic Acid (2015) (0)
- Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells (2018) (0)
- Abstract 631: Complementary Roles for 3-mercaptopyruvate Sulfurtransferase and Cystathionine γ-lyase in Angiogenesis (2019) (0)
- Angiogenesis and vascular stability in eicosanoids and cancer (2018) (0)
- Abstract 1175: The Proline-Rich Tyrosine Kinase Attenuates eNOS Activity in Shear Stress-Stimulated Endothelial Cells by the Phosphorylation of Tyr657 (2006) (0)
- Vasostatin-2, angiogenesis and collateral function. (2023) (0)
- Vascular Biology and Medicine: 3rd European Meeting, Hamburg, September 2005: Abstracts (2005) (0)
- Conference Calendar (2005) (0)
- A prickly situation: competitive antagonism by different hedgehog proteins (0)
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What Schools Are Affiliated With Ingrid Fleming?
Ingrid Fleming is affiliated with the following schools: