Irma Gigli
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Imunologist
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Irma Giglibiology Degrees
Biology
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Immunology
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Biology
Irma Gigli's Degrees
- PhD Immunology Stanford University
- Masters Biomedical Sciences University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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Why Is Irma Gigli Influential?
(Suggest an Edit or Addition)According to Wikipedia, Irma Gigli is an emeritus professor at the University of Texas Health Science Center at Houston, and the Walter & Mary Mischer Distinguished Professor in Molecular Medicine, Hans J. Müller-Eberhard Chair in Immunology, and Director Emeritus of the IMM Center for Immunology & Autoimmune Diseases.
Irma Gigli's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum. (1966) (565)
- Modulation of the classical pathway C3 convertase by plasma proteins C4 binding protein and C3b inactivator. (1979) (334)
- The complement system of man. 3. (1972) (295)
- Complement dependent immune phagocytosis. I. Requirements for C'1, C'4, C'2, C'3. (1968) (268)
- Human C4-binding protein. II. Role in proteolysis of C4b by C3b- inactivator (1978) (256)
- Human C4-binding protein. I. Isolation and characterization (1978) (237)
- Interaction of plasma kallikrein with the C1 inhibitor. (1970) (187)
- Enhancement of random migration and chemotactic response of human leukocytes by ascorbic acid. (1974) (179)
- The stoichiometric measurement of the serum inhibition of the first component of complement by the inhibition of immune hemolysis. (1968) (163)
- The unactivated form of the first component of human complement, C1. (1976) (148)
- Two distinct cellular patterns in cutaneous necrotizing angiitis. (1976) (139)
- Effect of glucocorticosteroids on epidermal Langerhans cells (1982) (138)
- Altered erythrocyte C3b receptor expression, immune complexes, and complement activation in homosexual men in varying risk groups for acquired immune deficiency syndrome. (1986) (118)
- The extracellular neutral cysteine proteinase of Entamoeba histolytica degrades anaphylatoxins C3a and C5a. (1995) (113)
- Urticaria and arthralgias as manifestations of necrotizing angiitis (vasculitis). (1974) (106)
- Evidence for a role for anti‐Müllerian hormone in the suppression of follicle activation in mouse ovaries and bovine ovarian cortex grafted beneath the chick chorioallantoic membrane (2005) (103)
- The structure and enzymic activities of the C1r and C1s subcomponents of C1, the first component of human serum complement. (1977) (98)
- Phylogeny and function of the complement system. (1971) (90)
- Activation of the guinea pig alternative complement pathway by mouse IgA immune complexes (1982) (86)
- Cleavage of C3 by a neutral cysteine proteinase of Entamoeba histolytica. (1989) (86)
- The isolation and structure of C4, the fourth component of human complement. (1977) (82)
- The complement system of man. I. (1972) (77)
- Evolutionary relationships among proteins encoded by the regulator of complement activation gene cluster. (2000) (74)
- Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59. (1995) (72)
- Structural and functional differences between the H-2 controlled Ss and Slp proteins (1978) (71)
- Mechanism of tetracycline phototoxicity. (1984) (71)
- Activation of the complement system in patients with porphyrias after irradiation in vivo. (1984) (70)
- Activation of complement by pathogenic and nonpathogenic Entamoeba histolytica. (1986) (68)
- Graft-versus-host reaction. Cutaneous manifestations following bone marrow transplantation. (1977) (65)
- The complement system in necrotizing angiitis of the skin. Analysis of complement component activities in serum of patients with concomitant collagen-vascular diseases. (1974) (64)
- Lysis of complement-sensitive Entamoeba histolytica by activated terminal complement components. Initiation of complement activation by an extracellular neutral cysteine proteinase. (1990) (62)
- Expression and localization of proteins of the complement system in human skin. (1992) (61)
- Staining of Langerhans cells with monoclonal antibodies to macrophages and lymphoid cells. (1983) (58)
- The complement system of man (second of four parts). (1972) (58)
- Role of complement in porphyrin-induced photosensitivity. (1981) (58)
- Neonatal lupus erythematosus with heart block: family study of a patient with anti-SS-A and SS-B antibodies. (1983) (56)
- The interaction of human plasma fibronectin with a subunit of the first component of complement, C1q. (1982) (55)
- Generation of chemotactic activity in serum from patients with erythropoietic protoporphyria and porphyria cutanea tarda. (1981) (53)
- Participation of mast cells and complement in the immediate phase of hematoporphyrin-induced phototoxicity. (1984) (51)
- Inhibition by ɛ-Aminocaproic Acid of the Activation of the First Component of the Complement System (1975) (46)
- Langerhans cells: role in contact hypersensitivity and relationship to lymphoid dendritic cells and to macrophages. (1980) (43)
- Fluid phase destruction of C2hu by C1hu. I. Its enhancement and inhibition by homologous and heterologous C4. (1969) (43)
- Differential effects of protoporphyrin and uroporphyrin on murine mast cells. (1987) (40)
- The complement system of man. 4. (1972) (40)
- A neutrophil immobilizing factor derived from human leukocytes. II. Specificity of action on polymorphonuclear leukocyte mobility. (1973) (40)
- Erythropoietic protoporphyria. Photoactivation of the complement system. (1980) (39)
- The fourth component of human complement treated with amines or chaotropes or frozen-thawed (C4b-like C4): interaction with C4 binding protein and cleavage by C3b/C4b inactivator. (1982) (39)
- Effects of oxygen tension and supplements to the culture medium on activation and development of bovine follicles in vitro. (2006) (38)
- Effect of indomethacin on alteration of ATPase-positive Langerhans cell density and cutaneous sunburn reaction induced by ultraviolet-B radiation. (1983) (38)
- The Complement Cofactor Protein (SBP1) from the Barred Sand Bass (Paralabrax nebulifer) Mediates Overlapping Regulatory Activities of Both Human C4b Binding Protein and Factor H* (1998) (36)
- Delayed phase of hematoporphyrin-induced phototoxicity: modulation by complement, leukocytes, and antihistamines. (1985) (36)
- The effect of fibronectin on the processing of C1q- and C3b/bi-coated immune complexes by peripheral blood monocytes. (1986) (35)
- Phylogeny of C4b-C3b cleaving activity: similar fragmentation patterns of human C4b and C3b produced by lower animals. (1987) (35)
- Fibronectin binding to complement subcomponent C1q. Localization of their respective binding sites. (1985) (35)
- Cloning and characterization of a cDNA representing a putative complement-regulatory plasma protein from barred sand bass (Parablax neblifer). (1994) (35)
- A newly described control mechanism of complement activation in patients with mixed cryoglobulinemia (cryoglobulins and complement). (1980) (34)
- FLUID PHASE DESTRUCTION OF C2hu BY C1hu II. UNMASKING BY C4ihu OF C1hu SPECIFICITY FOR C2hu (1969) (33)
- Endocytosis and shedding of the decay accelerating factor on human polymorphonuclear cells. (1989) (32)
- Mechanism of action of the C4 nephritic factor. Deregulation of the classical pathway of C3 convertase (1981) (32)
- Receptors for complement of Langerhans cells. (1980) (31)
- A single chain precursor of C4 in human serum (1978) (29)
- Effect of glucocorticoids and gamma radiation on epidermal Langerhans cells. (1984) (29)
- Ancient Origin of Human Complement Factor H (1998) (28)
- Complement receptors on guinea pig epidermal Langerhans cells. (1980) (27)
- Regulation and deregulation of the fluid-phase classical pathway C3 convertase. (1985) (27)
- Phylogeny of regulatory proteins of the complement system. Isolation and characterization of a C4b/C3b inhibitor and a cofactor from sand bass plasma. (1989) (26)
- Lung injury induced by antibody fragments to angiotensin-converting enzyme. (1981) (25)
- Mechanism of killing of Giardia lamblia trophozoites by complement. (1987) (25)
- Histamine release from rodent and human mast cells induced by protoporphyrin and ultraviolet light: studies of the mechanism of mast‐cell activation in erythropoietic protoporphyria (1990) (25)
- Complement-derived chemotactic activity is generated in human serum containing uroporphyrin after irradiation with 405 nm light. (1981) (25)
- MODULATION OF FUNCTION OF THE ACTIVATED FIRST COMPONENT OF COMPLEMENT BY A FRAGMENT DERIVED FROM SERUM (1971) (24)
- Role of complement and polymorphonuclear cells in demethylchlortetracycline-induced phototoxicity in guinea pigs. Inhibition by decomplementation in vivo. (1983) (24)
- Cloning and recombinant expression of a barred sand bass (Paralabrax nebulifer) cDNA. The encoded protein displays structural homology and immunological crossreactivity to human complement/cofactor related plasma proteins. (1996) (23)
- PHOTOTOXICITY INDUCED BY HEMATOPORPHYRIN DERIVATIVE IN C5‐DEFICIENT, MAST CELL‐DEFICIENT AND LEUKOPENIC MICE (1986) (22)
- Conformational changes in complement component C4 induced by activation, treatment with amines, chaotropes, or freezing-thawing, detectable by radioiodination using lactoperoxidase. (1982) (22)
- Leprosy: altered complement receptors in disseminated disease. (1985) (21)
- The human C3b receptor: function and role in human diseases. (1990) (20)
- Mouse C3b/C4b inactivator: purification and properties. (1980) (20)
- Presence of a C4-Binding Protein (C4-bp) in Human Serum (1978) (18)
- Erythema nodosum type of lepra reaction. General consideration and report of three cases treated with long-term adrenocorticosteroid therapy. (1962) (18)
- Immunochemistry and immunobiology of the complement system. (1976) (17)
- Chido and Rogers antigenic determinant on the fourth component of human complement. (1982) (17)
- [Antigen fixation by circulating leukocytes in delayed local insulin allergy]. (1966) (15)
- Conservation of Plasma Regulatory Proteins of the Complement System in Evolution: Humans and Fish (2000) (15)
- Requirements for the binding of human plasma fibronectin to the C1q subunit of the first component of complement. (1983) (15)
- Killing of human melanoma cells by the membrane attack complex of human complement as a function of its molecular composition. (1987) (15)
- Dual effects of protoporphyrin and long wave ultraviolet light on histamine release from rat peritoneal and cutaneous mast cells. (1990) (15)
- Effect of combined topical glucocorticoids and ultraviolet B irradiation on epidermal Langerhans cells. (1984) (14)
- Hyperimmunoglobulin E syndrome. (1978) (13)
- Langerhans' cells in paracoccidioidomycosis. (1987) (13)
- Participation of an early component of complement and Hageman factor in C3 destruction by zymosan. (1975) (13)
- Langerhans cells and interdigitating cells in HIV-infection. (1993) (12)
- Fibronectin Binding to C1q Associated with Antigen‐Antibody Complexes in EDTA‐treated Plasma (1986) (12)
- Inhibition of the lytic effect of guinea pig complement by rabbit complement. (1969) (12)
- Blocking of the hemolytic expression of the classical complement sequence by products of complement activation via the alternate pathway. Materials responsible for the blocking phenomenon and their proposed mechanism of action. (1973) (11)
- Should we limit sugar in acne? (1961) (11)
- Control mechanisms of the classical and alternate complement sequences. (1974) (10)
- Inhibition of human peripheral blood lymphocyte function by protoporphyrin and longwave ultraviolet light. (1994) (10)
- Non‐newtonian behavior of polymers with log‐normal molecular weight distribution (1966) (8)
- The complement system in inflammation and host defence (1979) (8)
- Fluid phase destruction of C2 hu by C1 hu. 3. Changes in activity for synthetic substrates upon cell binding, heat inactivation and interaction with C1INH. (1972) (8)
- Effect of captopril on the vascular permeability changes induced by C5a, histamine and compound 48/80 (1985) (8)
- The expression of C3b receptors in the differentiation of discoid lupus erythematosus and systemic lupus erythematosus. (1990) (7)
- Differentiation of binding from complete activation by use of heterologous components of complement. (1972) (7)
- Deficiency of erythrocyte C3b receptor (CR1) in AIDS and AIDS-related syndromes (1986) (7)
- Inhibition of mast cell mediator secretion induced by protoporphyrin plus long-wave ultraviolet light: a morphometric and ultrastructural analysis. (1994) (6)
- Mechanism of complement action in rosette inhibition and lymphocytotoxicity of antilymphocyte serum. (1972) (6)
- Modulation of human cutaneous mast cell responsiveness by a single, low-dose, PUVA treatment. (1991) (6)
- Perturbations of Complement in Disease (1977) (4)
- C1, C4, and C2 components of the classical pathway of complement and regulatory proteins. (1988) (4)
- Langerhans cells in connective tissue diseases. (1987) (4)
- Protoporphyrin and long-wave ultraviolet light modulate metabolic events in rat peritoneal mast cells. (1992) (4)
- Interaction of the fourth component of human complement, treated with amines, chaotropes or frozen-thawed (C4b-like C4), with C4 binding protein and cleavage by C3b/C4b inactivator (1982) (4)
- FLUID PHASE DESTRUCTION OF C2hu BY C1hu (1969) (4)
- Complement activation in patients with mixed cryoglobulinemia (cryoglobulins and complement) (1986) (4)
- Restriction of the Substrate Specificity of C1 Human by Heat Inactivation or Cell Binding (1971) (4)
- A phagocytosis-enhancing factor in human plasma. (1976) (4)
- A theoretical interpretation of the BUECHE‐HARDING master curve (1967) (3)
- The ability of protoporphyrin plus long-wave ultraviolet light to inhibit calcium mobilization and mediator release in mast cells is not related to changes in phospholipid signaling pathways. (1991) (3)
- Inhibition by epsilon-aminocaproic acid of the activation of the first component of the complement system. (1975) (3)
- The Complement System (1981) (3)
- The complement cofactor protein (SBP1) from the barred sand bass (Paralabrax nebulifer) mediates overlapping regulatory activities of both human C4BP and factor H (1998) (3)
- Alterations in Fc epsilon RI induced by protoporphyrin plus long-wavelength ultraviolet light in mouse bone marrow-derived mast cells. (1993) (3)
- Interaction of DNA with the Early Components of Complement (1981) (2)
- Activation of complement by mouse iga immune complexes. Abstr. (1978) (2)
- FLUID PHASE DESTRUCTION OF C2hu BY C1hu (1969) (2)
- a conformational change in complement component C4 induced by activation or treatment with amines, chaotropes or freezing and thawing (1982) (2)
- [Hypersensitivity and immunologic tolerance in contact allergies]. (1982) (2)
- Interaction of pathogenic and nonpathogenic Entamoeba histolytica with human complement. (1987) (2)
- Eczematous and immunologic diseases. (1984) (2)
- Altered Erythrocyte C 3 b Receptor Expression , Immune Complexes , and Complement Activation in Homosexual Men in Varying Risk Groups for Acquired Immune Deficiency Syndrome (2013) (2)
- The role of complement in phototoxic reactions (2005) (1)
- Alteration in Complement Component Utilization Following the Interaction of C1̄hu with a Kallikrein Fragment (1971) (1)
- Release of Proinflammatory Peptides by Complement in Porphyrin-induced Photosensitivity (1981) (1)
- Simultaneous deficiencies of early components of complement (C) and hageman factor (Factor XII) (1973) (1)
- Phylogeny of the plasma regulatory proteins of the complement system. (1989) (1)
- [Complement and its role in immune reactions]. (1969) (1)
- Pulmonary Endothelial Cell Injury Induced by Antibody Fragments to Angiotensin Converting Enzyme (1982) (1)
- CR1 deficiency in patients with Hansen's disease. (1984) (1)
- [Distribution and inhibition of human esterolytic dermoproteinases]. (1969) (1)
- An explanation for the inefficiency of guinea pig complement in the cytolysis of sheep erythrocytes or rat mast cells sensitized with rabbit antiserum: a double block. (1969) (1)
- Workshop on immune mechanisms in cutaneous disorders. (1980) (1)
- Form 990 Return of Organization Exempt From Income Tax 2012 (2013) (0)
- Pharmaceutical Manipulations of the Complement Cascade (1988) (0)
- Killing of human melanoma cells by the membrane attack complex (MAC) as a function of its molecular composition (1986) (0)
- Abstracts of Papers Presented at the Third International Complement Workshop, Harvard Medical School, Boston, Massachusetts, June 3–5, 1968 (1968) (0)
- Principles of Immunology (Book) (1974) (0)
- Evolution relationships among SCR containing proteins (1998) (0)
- Cellular Selection and Regulatin in the Immune Response (Book) (1975) (0)
- Effect of indomethacin (IND) on alteration of Langerhans cell (LC) density induced by ultraviolet (UV)-B irradiation of guinea pigs (GPs) (1982) (0)
- ANALYSIS OF INTERACTIONS BETWEEN C3b, C3bi, FACTOR H, C4bp AND FACTOR I (1991) (0)
- Suppression of phototoxic reaction induced by demethylchlortetracycline (DMCT) in guinea pigs (GPs) depleted of complement and/or polymorphonuclear cells (PMNs) (1982) (0)
- C3 Destruction in Serum by Zymosan: Dependency on the Early Components of C and Hageman Factor (1973) (0)
- Complement proteins and receptors in the microenvironment of the skin (1998) (0)
- A study on the immunological properties of human uterine and placental contractile protein by immuneadherence (2005) (0)
- Acquired C1 inhibitor deficiency: postmortem diagnosis. (1990) (0)
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